BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 13354 CNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CC2)NC(=O)N(C)C)CC1 InChI=1S/C20H33Cl2N7O/c1-23-19-25-17(22)16(21)18(26-19)29-12-10-28(11-13-29)9-8-14-4-6-15(7-5-14)24-20(30)27(2)3/h14-15H,4-13H2,1-3H3,(H,24,30)(H,23,25,26) HLQCCYMMQYUZFZ-UHFFFAOYSA-N 6775 US8802672, 8 D(2) dopamine receptor Rattus norvegicus 35 US Patent 10.7270/Q2FF3R1T aid1800622 US8802672 Szalai, GB; Csongor, EA; Domany, G; Gyertyan, I; Kiss, B; Laszy, J; Saghy, K; Schmidt, E; Farkas, S; Komlodi, Z Richter Gedeon Nyrt. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25052177 242052768 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53835 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)CCC2=O)CC1 InChI=1S/C19H24F3N3O2/c20-19(21,22)15-4-3-5-16(14-15)24-12-10-23(11-13-24)8-1-2-9-25-17(26)6-7-18(25)27/h3-5,14H,1-2,6-13H2 PEQJTCZGJSKPGE-UHFFFAOYSA-N 29556 1-(m-trifluorophenyl)piperazine, 3 D(2) dopamine receptor Rattus norvegicus >30000 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42618268 81054985 ZINC13678543 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53836 FC(F)(F)c1cccc(c1)N1CCN(CC1)C1CCC(CC1)N1C(=O)CCC1=O InChI=1S/C21H26F3N3O2/c22-21(23,24)15-2-1-3-18(14-15)26-12-10-25(11-13-26)16-4-6-17(7-5-16)27-19(28)8-9-20(27)29/h1-3,14,16-17H,4-13H2 LRFXCMMDVYGXJF-UHFFFAOYSA-N 29557 1-(m-trifluorophenyl)piperazine, 4 D(2) dopamine receptor Rattus norvegicus >25000 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11292754 81054986 ZINC13678527 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53837 CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2cccc(c2)C(F)(F)F)C(=O)C1 InChI=1S/C22H30F3N3O2/c1-21(2)15-19(29)28(20(30)16-21)9-4-3-8-26-10-12-27(13-11-26)18-7-5-6-17(14-18)22(23,24)25/h5-7,14H,3-4,8-13,15-16H2,1-2H3 UDSHNEUEZSPXAV-UHFFFAOYSA-N 29558 1-(m-trifluorophenyl)piperazine, 5 D(2) dopamine receptor Rattus norvegicus 2340 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23661734 81054987 ZINC13678549 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53838 CC1(C)CC(=O)N(C2CCC(CC2)N2CCN(CC2)c2cccc(c2)C(F)(F)F)C(=O)C1 InChI=1S/C24H32F3N3O2/c1-23(2)15-21(31)30(22(32)16-23)19-8-6-18(7-9-19)28-10-12-29(13-11-28)20-5-3-4-17(14-20)24(25,26)27/h3-5,14,18-19H,6-13,15-16H2,1-2H3 SWCGWBOIEXHVNM-UHFFFAOYSA-N 29559 1-(m-trifluorophenyl)piperazine, 6 D(2) dopamine receptor Rattus norvegicus >10000 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11453751 81054988 ZINC13678537 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53839 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)CCCC2=O)CC1 InChI=1S/C20H26F3N3O2/c21-20(22,23)16-5-3-6-17(15-16)25-13-11-24(12-14-25)9-1-2-10-26-18(27)7-4-8-19(26)28/h3,5-6,15H,1-2,4,7-14H2 RGMHIFQLKSXUQM-UHFFFAOYSA-N 29560 1-(m-trifluorophenyl)piperazine, 7 D(2) dopamine receptor Rattus norvegicus >5000 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42618269 81054989 ZINC28876249 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53840 FC(F)(F)c1cccc(c1)N1CCN(CC1)C1CCC(CC1)N1C(=O)CCCC1=O InChI=1S/C22H28F3N3O2/c23-22(24,25)16-3-1-4-19(15-16)27-13-11-26(12-14-27)17-7-9-18(10-8-17)28-20(29)5-2-6-21(28)30/h1,3-4,15,17-18H,2,5-14H2 QPDOXFZMEXGLGN-UHFFFAOYSA-N 29561 1-(m-trifluorophenyl)piperazine, 8 D(2) dopamine receptor Rattus norvegicus >5000 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23661735 81054990 ZINC28876254 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53841 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)C3=C(CCCC3)C2=O)CC1 InChI=1S/C23H28F3N3O2/c24-23(25,26)17-6-5-7-18(16-17)28-14-12-27(13-15-28)10-3-4-11-29-21(30)19-8-1-2-9-20(19)22(29)31/h5-7,16H,1-4,8-15H2 HTUTXORRNIHWIV-UHFFFAOYSA-N 29562 1-(m-trifluorophenyl)piperazine, 9 D(2) dopamine receptor Rattus norvegicus >5000 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42618270 81054991 ZINC28876259 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53842 FC(F)(F)c1cccc(c1)N1CCN(CC1)C1CCC(CC1)N1C(=O)C2=C(CCCC2)C1=O InChI=1S/C25H30F3N3O2/c26-25(27,28)17-4-3-5-20(16-17)30-14-12-29(13-15-30)18-8-10-19(11-9-18)31-23(32)21-6-1-2-7-22(21)24(31)33/h3-5,16,18-19H,1-2,6-15H2 RERVVDVRYYKMKB-UHFFFAOYSA-N 29563 1-(m-trifluorophenyl)piperazine, 10 D(2) dopamine receptor Rattus norvegicus 2640 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42618271 81054992 ZINC28876265 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53843 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)C3CC=CCC3C2=O)CC1 InChI=1S/C23H28F3N3O2/c24-23(25,26)17-6-5-7-18(16-17)28-14-12-27(13-15-28)10-3-4-11-29-21(30)19-8-1-2-9-20(19)22(29)31/h1-2,5-7,16,19-20H,3-4,8-15H2 QNXBNMZKKDROGR-UHFFFAOYSA-N 29564 1-(m-trifluorophenyl)piperazine, 11 D(2) dopamine receptor Rattus norvegicus 2720 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42618272 81054993 ZINC28876268 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53844 FC(F)(F)c1cccc(c1)N1CCN(CC1)C1CCC(CC1)N1C(=O)C2CC=CCC2C1=O InChI=1S/C25H30F3N3O2/c26-25(27,28)17-4-3-5-20(16-17)30-14-12-29(13-15-30)18-8-10-19(11-9-18)31-23(32)21-6-1-2-7-22(21)24(31)33/h1-5,16,18-19,21-22H,6-15H2 OBKXULMELCPTCP-UHFFFAOYSA-N 29565 1-(m-trifluorophenyl)piperazine, 12 D(2) dopamine receptor Rattus norvegicus 4680 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42618273 81054994 ZINC28876290 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53845 CC1=C(C)C(=O)N(CCCCN2CCN(CC2)c2cccc(c2)C(F)(F)F)C1=O InChI=1S/C21H26F3N3O2/c1-15-16(2)20(29)27(19(15)28)9-4-3-8-25-10-12-26(13-11-25)18-7-5-6-17(14-18)21(22,23)24/h5-7,14H,3-4,8-13H2,1-2H3 BMSXPMKILQCSPH-UHFFFAOYSA-N 29566 1-(m-trifluorophenyl)piperazine, 13 D(2) dopamine receptor Rattus norvegicus 4370 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42618274 81054995 ZINC62233490 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 53846 CC1=C(C)C(=O)N(C2CCC(CC2)N2CCN(CC2)c2cccc(c2)C(F)(F)F)C1=O InChI=1S/C23H28F3N3O2/c1-15-16(2)22(31)29(21(15)30)19-8-6-18(7-9-19)27-10-12-28(13-11-27)20-5-3-4-17(14-20)23(24,25)26/h3-5,14,18-19H,6-13H2,1-2H3 PGBRELWAWYYWAN-UHFFFAOYSA-N 29567 1-(m-trifluorophenyl)piperazine, 14 D(2) dopamine receptor Rattus norvegicus 3600 Curated from the literature by BindingDB 10.1016/j.bmc.2007.07.029 10.7270/Q2G15Z6G 17825569 aid1799015 Paluchowska, MH; Bugno, R; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Lenda, T; Chojnacka-Wójcik, E Polish Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42618275 81054996 ZINC62233493 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025858 CN1CCc2cc(Cl)c(O)cc2[C@H]2[C@@H]1CCc1ccccc21 InChI=1S/C19H20ClNO/c1-21-9-8-13-10-16(20)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-17(19)21/h2-5,10-11,17,19,22H,6-9H2,1H3/t17-,19-/m0/s1 DMJWENQHWZZWDF-HKUYNNGSSA-N 50010711 (6aR,13bS )11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL56666::cis-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::cis-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol D(2) dopamine receptor Rattus norvegicus 9073 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010711&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14787976 103923457 CHEMBL56666 ZINC08586471 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157077 CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3 SNPPWIUOZRMYNY-UHFFFAOYSA-N 50048392 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one::BUPROPION::BUPROPION HYDROCHLORIDE::CHEMBL894::US9944618, Compound ID No. 176 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0014-2999(89)90363-4 10.7270/Q28C9TR3 2530094 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048392&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 444 103978858 3219 CHEMBL894 DB01156 7135 C06860 ZINC00057206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157078 CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1 InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3 WSEQXVZVJXJVFP-UHFFFAOYSA-N 25870 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile::CHEMBL549::CITALOPRAM::CITALOPRAM HYDROBROMIDE::Escitalopram::[3H]Citalopram::[3H]Cytalopram::[3H]Escitalopram::[3H]Lexapro D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0014-2999(89)90363-4 10.7270/Q28C9TR3 2530094 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68P 5I73,5I71,5I75 2771 56413158 3723 CHEMBL549 DB00215 4621 C07572 ZINC03800706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157079 Fc1ccc(cc1)C(OCCN1CCN(CCCc2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2 NAUWTFJOPJWYOT-UHFFFAOYSA-N 22165 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine::CHEMBL153260::CHEMBL281594::CHEMBL542933::CHEMBL543876::GBR 12909::GBR-12909::NCGC00015300::US9944618, Compound ID No. 175::Vanoxerine D(2) dopamine receptor Rattus norvegicus 270 PDSP Ki 10.1016/0014-2999(89)90363-4 10.7270/Q28C9TR3 2530094 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3455 49845980 64089 CHEMBL153260CHEMBL281594CHEMBL543876CHEMBL542933 ZINC22034135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157080 CN(C)CCCN1c2ccccc2CCc2ccccc12 InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3 BCGWQEUPMDMJNV-UHFFFAOYSA-N 50010859 CHEMBL11::IMIPRAMINE HYDROCHLORIDE::IMIPRAMINE PAMOATE::Imipramin D(2) dopamine receptor Rattus norvegicus 942 PDSP Ki 10.1016/0014-2999(89)90363-4 10.7270/Q28C9TR3 2530094 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search IXX 2Q72,7LWD,6G9B 3696 103923605 47499 CHEMBL11 DB00458 357 C07049 ZINC00020245 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157081 CN1CC(c2ccccc2)c2cccc(N)c2C1 InChI=1S/C16H18N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h2-9,14H,10-11,17H2,1H3 XXPANQJNYNUNES-UHFFFAOYSA-N 50005548 (+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::(+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::(-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::(Nomifensine) 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine (Nomifensine)::2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine(Nomifensine)::2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine::CHEMBL273575::NOMIFENSINE::NOMIFENSINE2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0014-2999(89)90363-4 10.7270/Q28C9TR3 2530094 Andersen, PH Novo Industri A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4528 103919027 116225 CHEMBL273575 DB04821 4792 ZINC19796035 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157139 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 313 PDSP Ki 10.1016/0024-3205(89)90523-7 10.7270/Q20Z71SN 2531826 Sanchez-Roa, PM; Grigoriadis, DE; Wilson, AA; Sharkey, J; Dannals, RF; Villemagne, VL; Wong, DF; Wagner, HN; Kuhar, MJ NIDA Addiction Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157140 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 0.97 PDSP Ki 10.1016/0024-3205(89)90523-7 10.7270/Q20Z71SN 2531826 Sanchez-Roa, PM; Grigoriadis, DE; Wilson, AA; Sharkey, J; Dannals, RF; Villemagne, VL; Wong, DF; Wagner, HN; Kuhar, MJ NIDA Addiction Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157141 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.04 PDSP Ki 10.1016/0024-3205(89)90523-7 10.7270/Q20Z71SN 2531826 Sanchez-Roa, PM; Grigoriadis, DE; Wilson, AA; Sharkey, J; Dannals, RF; Villemagne, VL; Wong, DF; Wagner, HN; Kuhar, MJ NIDA Addiction Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157142 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.65 PDSP Ki 10.1016/0024-3205(89)90523-7 10.7270/Q20Z71SN 2531826 Sanchez-Roa, PM; Grigoriadis, DE; Wilson, AA; Sharkey, J; Dannals, RF; Villemagne, VL; Wong, DF; Wagner, HN; Kuhar, MJ NIDA Addiction Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157143 CNc1cc(OC)c(cc1Cl)C(=O)NCCN(C)Cc1ccc(I)cc1 InChI=1S/C19H23ClIN3O2/c1-22-17-11-18(26-3)15(10-16(17)20)19(25)23-8-9-24(2)12-13-4-6-14(21)7-5-13/h4-7,10-11,22H,8-9,12H2,1-3H3,(H,23,25) SSXZAENYAVXXOA-UHFFFAOYSA-N 81950 CAS_130377::NSC_130377::Spectramide D(2) dopamine receptor Rattus norvegicus 0.13 PDSP Ki 10.1016/0024-3205(89)90523-7 10.7270/Q20Z71SN 2531826 Sanchez-Roa, PM; Grigoriadis, DE; Wilson, AA; Sharkey, J; Dannals, RF; Villemagne, VL; Wong, DF; Wagner, HN; Kuhar, MJ NIDA Addiction Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130377 131342524 ZINC14953604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157144 CNc1cc(OC)c(cc1Cl)C(=O)NCCN(C)Cc1ccc(I)cc1 InChI=1S/C19H23ClIN3O2/c1-22-17-11-18(26-3)15(10-16(17)20)19(25)23-8-9-24(2)12-13-4-6-14(21)7-5-13/h4-7,10-11,22H,8-9,12H2,1-3H3,(H,23,25) SSXZAENYAVXXOA-UHFFFAOYSA-N 81950 CAS_130377::NSC_130377::Spectramide D(2) dopamine receptor Rattus norvegicus 0.215 PDSP Ki 10.1016/0024-3205(89)90523-7 10.7270/Q20Z71SN 2531826 Sanchez-Roa, PM; Grigoriadis, DE; Wilson, AA; Sharkey, J; Dannals, RF; Villemagne, VL; Wong, DF; Wagner, HN; Kuhar, MJ NIDA Addiction Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130377 131342524 ZINC14953604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157145 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.02 PDSP Ki 10.1016/0024-3205(89)90523-7 10.7270/Q20Z71SN 2531826 Sanchez-Roa, PM; Grigoriadis, DE; Wilson, AA; Sharkey, J; Dannals, RF; Villemagne, VL; Wong, DF; Wagner, HN; Kuhar, MJ NIDA Addiction Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157146 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 6.58 PDSP Ki 10.1016/0024-3205(89)90523-7 10.7270/Q20Z71SN 2531826 Sanchez-Roa, PM; Grigoriadis, DE; Wilson, AA; Sharkey, J; Dannals, RF; Villemagne, VL; Wong, DF; Wagner, HN; Kuhar, MJ NIDA Addiction Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157147 NC1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2 ASXGAOFCKGHGMF-UHFFFAOYSA-N 81195 (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide::2-aminotetralin-6,7-diol;hydrobromide::6-Amino-5,6,7,8-tetrahydro-naphthalene-2,3-diol::6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::6-azanyl-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::ADTN::ADTN, (+)::CA inhibitor, 3::CHEMBL26736::MLS002172466::SMR001254097::cid_11957526::cid_3153 D(2) dopamine receptor Rattus norvegicus 1.07 PDSP Ki 10.1016/0024-3205(89)90523-7 10.7270/Q20Z71SN 2531826 Sanchez-Roa, PM; Grigoriadis, DE; Wilson, AA; Sharkey, J; Dannals, RF; Villemagne, VL; Wong, DF; Wagner, HN; Kuhar, MJ NIDA Addiction Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3153 252657735 CHEMBL26736 ZINC03872370 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157148 NC1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2 ASXGAOFCKGHGMF-UHFFFAOYSA-N 81195 (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide::2-aminotetralin-6,7-diol;hydrobromide::6-Amino-5,6,7,8-tetrahydro-naphthalene-2,3-diol::6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::6-azanyl-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::ADTN::ADTN, (+)::CA inhibitor, 3::CHEMBL26736::MLS002172466::SMR001254097::cid_11957526::cid_3153 D(2) dopamine receptor Rattus norvegicus 24.91 PDSP Ki 10.1016/0024-3205(89)90523-7 10.7270/Q20Z71SN 2531826 Sanchez-Roa, PM; Grigoriadis, DE; Wilson, AA; Sharkey, J; Dannals, RF; Villemagne, VL; Wong, DF; Wagner, HN; Kuhar, MJ NIDA Addiction Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3153 252657735 CHEMBL26736 ZINC03872370 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157154 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157155 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157157 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157158 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 1.6 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157160 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 5.1 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157161 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 5.8 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157163 CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 UEQUQVLFIPOEMF-GOSISDBHSA-N 35256 (S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon D(2) dopamine receptor Rattus norvegicus 4300 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154315 85753335 51137 ZINC00000855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157164 CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 UEQUQVLFIPOEMF-GOSISDBHSA-N 35256 (S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon D(2) dopamine receptor Rattus norvegicus 4600 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154315 85753335 51137 ZINC00000855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157166 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 2500 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157167 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 3300 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157169 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.35 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157170 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.56 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157172 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 160 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157173 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 205 PDSP Ki 10.1073/pnas.86.24.9762 10.7270/Q2W66J87 2532362 Grandy, DK; Marchionni, MA; Makam, H; Stofko, RE; Alfano, M; Frothingham, L; Fischer, JB; Burke-Howie, KJ; Bunzow, JR; Server, AC Oregon Health Sciences University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158515 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.6 PDSP Ki 10.1016/0024-3205(88)90493-6 10.7270/Q23J3BF5 3130534 Yasuda, Y; Kikuchi, T; Suzuki, S; Tsutsui, M; Yamada, K; Hiyama, T Tokushima Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158516 Cc1cccc(N2CCN(CCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1C InChI=1S/C24H29N3O2/c1-18-5-3-6-23(19(18)2)27-14-12-26(13-15-27)11-4-16-29-21-9-7-20-8-10-24(28)25-22(20)17-21/h3,5-10,17H,4,11-16H2,1-2H3,(H,25,28) RRLWEQBPSAFVAS-UHFFFAOYSA-N 82065 CAS_163839::NSC_163839::OPC-4392 D(2) dopamine receptor Rattus norvegicus 5.8 PDSP Ki 10.1016/0024-3205(88)90493-6 10.7270/Q23J3BF5 3130534 Yasuda, Y; Kikuchi, T; Suzuki, S; Tsutsui, M; Yamada, K; Hiyama, T Tokushima Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 163839 131342639 268 ZINC05116306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158517 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 150 PDSP Ki 10.1016/0024-3205(88)90493-6 10.7270/Q23J3BF5 3130534 Yasuda, Y; Kikuchi, T; Suzuki, S; Tsutsui, M; Yamada, K; Hiyama, T Tokushima Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157262 CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3 SNPPWIUOZRMYNY-UHFFFAOYSA-N 50048392 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one::BUPROPION::BUPROPION HYDROCHLORIDE::CHEMBL894::US9944618, Compound ID No. 176 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1111/j.1471-4159.1985.tb08803.x 10.7270/Q27H1H2F 2580950 Hyttel, J; Larsen, JJ Lundbeck AIS http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048392&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 444 103978858 3219 CHEMBL894 DB01156 7135 C06860 ZINC00057206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157263 CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1 InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3 WSEQXVZVJXJVFP-UHFFFAOYSA-N 25870 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile::CHEMBL549::CITALOPRAM::CITALOPRAM HYDROBROMIDE::Escitalopram::[3H]Citalopram::[3H]Cytalopram::[3H]Escitalopram::[3H]Lexapro D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1111/j.1471-4159.1985.tb08803.x 10.7270/Q27H1H2F 2580950 Hyttel, J; Larsen, JJ Lundbeck AIS http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68P 5I73,5I71,5I75 2771 56413158 3723 CHEMBL549 DB00215 4621 C07572 ZINC03800706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157264 COc1ccc2C(CN(C)Cc2c1)c1ccc(Cl)c(Cl)c1 InChI=1S/C17H17Cl2NO/c1-20-9-12-7-13(21-2)4-5-14(12)15(10-20)11-3-6-16(18)17(19)8-11/h3-8,15H,9-10H2,1-2H3 ZJDCGVDEEHWEIG-UHFFFAOYSA-N 50021895 4-(3,4-Dichloro-phenyl)-7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline::4-(3,4-Dichloro-phenyl)-7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline(Diclofensive)::CHEMBL287257::DICLOFENSINE,(+)::DICLOFENSINE,(-)::Diclofensine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1111/j.1471-4159.1985.tb08803.x 10.7270/Q27H1H2F 2580950 Hyttel, J; Larsen, JJ Lundbeck AIS http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021895&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68871 103932585 CHEMBL287257 ZINC29230278 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158582 CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 UEQUQVLFIPOEMF-GOSISDBHSA-N 35256 (S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0028-3908(88)90149-9 10.7270/Q2B27SSW 3419539 de Boer, TH; Maura, G; Raiteri, M; de Vos, CJ; Wieringa, J; Pinder, RM Organon International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154315 85753335 51137 ZINC00000855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158583 CN1CCN2C(C1)c1ccccc1Cc1cccnc21 InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3 RONZAEMNMFQXRA-UHFFFAOYSA-N 50115644 (+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::2-methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::CHEMBL654::MIRTAZAPINE::ORG 3770::REMERON D(2) dopamine receptor Rattus norvegicus 3981.07 PDSP Ki 10.1016/0028-3908(88)90149-9 10.7270/Q2B27SSW 3419539 de Boer, TH; Maura, G; Raiteri, M; de Vos, CJ; Wieringa, J; Pinder, RM Organon International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4205 104009532 6950 CHEMBL654 DB00370 7241 C07570 ZINC19702119 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158584 CN1CCN2C(C1)c1ccccc1Cc1cccnc21 InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3 RONZAEMNMFQXRA-UHFFFAOYSA-N 50115644 (+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::2-methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::CHEMBL654::MIRTAZAPINE::ORG 3770::REMERON D(2) dopamine receptor Rattus norvegicus 5011.87 PDSP Ki 10.1016/0028-3908(88)90149-9 10.7270/Q2B27SSW 3419539 de Boer, TH; Maura, G; Raiteri, M; de Vos, CJ; Wieringa, J; Pinder, RM Organon International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4205 104009532 6950 CHEMBL654 DB00370 7241 C07570 ZINC19702119 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158585 CN1CCN2C(C1)c1ccccc1Cc1cccnc21 InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3 RONZAEMNMFQXRA-UHFFFAOYSA-N 50115644 (+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::2-methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::CHEMBL654::MIRTAZAPINE::ORG 3770::REMERON D(2) dopamine receptor Rattus norvegicus 3981.07 PDSP Ki 10.1016/0028-3908(88)90149-9 10.7270/Q2B27SSW 3419539 de Boer, TH; Maura, G; Raiteri, M; de Vos, CJ; Wieringa, J; Pinder, RM Organon International http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4205 104009532 6950 CHEMBL654 DB00370 7241 C07570 ZINC19702119 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156048 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 24 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156050 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 5.3 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156053 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 2.8 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156055 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 56 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156057 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 2.8 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156058 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 474 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156059 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/p-1/t3-,5-,6-,9-/m1/s1 XKMLYUALXHKNFT-UUOKFMHZSA-M 81874 Dopamine+ (GTP+)::Dopamine+GTP::NPA+ (GTP+) D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91898390 131342448 15996 C03517 ZINC60094177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157265 Fc1ccc(cc1)C(OCCN1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C28H30F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-15,28H,16-22H2/b7-4+ DASHZBBQOARCMQ-QPJJXVBHSA-N 22199 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine::CHEMBL112280::CHEMBL286991::GBR 12935 Analogue, 36::GBR-13,069 D(2) dopamine receptor Rattus norvegicus 810 PDSP Ki 10.1111/j.1471-4159.1985.tb08803.x 10.7270/Q27H1H2F 2580950 Hyttel, J; Larsen, JJ Lundbeck AIS http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22199&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5974189 49846014 CHEMBL112280CHEMBL286991 ZINC22454217 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157266 CN[C@H]1C[C@@H](c2ccccc12)c1ccc(Cl)c(Cl)c1 InChI=1S/C16H15Cl2N/c1-19-16-9-13(11-4-2-3-5-12(11)16)10-6-7-14(17)15(18)8-10/h2-8,13,16,19H,9H2,1H3/t13-,16+/m1/s1 SVFXPTLYMIXFRX-CJNGLKHVSA-N 81946 CAS_96850-13-4::LU 19,005::LU 19-005 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1111/j.1471-4159.1985.tb08803.x 10.7270/Q27H1H2F 2580950 Hyttel, J; Larsen, JJ Lundbeck AIS http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2794225 131342520 ZINC00001565 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157267 C(CN1CCN(C\C=C\c2ccccc2)CC1)OC(c1ccccc1)c1ccccc1 InChI=1S/C28H32N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-17,28H,18-24H2/b13-10+ XFBDGHFDKJITGC-JLHYYAGUSA-N 81954 1-(2-Benzhydryloxy-ethyl)-4-((E)-3-phenyl-allyl)-piperazine dihydrochloride::CAS_67469-75-4::Lu 2-098 D(2) dopamine receptor Rattus norvegicus 2500 PDSP Ki 10.1111/j.1471-4159.1985.tb08803.x 10.7270/Q27H1H2F 2580950 Hyttel, J; Larsen, JJ Lundbeck AIS http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5788723 131342528 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157268 CN(C)C[C@@H]1C2CCC(CC2)[C@@H]1c1ccc(Cl)c(Cl)c1 InChI=1S/C17H23Cl2N/c1-20(2)10-14-11-3-5-12(6-4-11)17(14)13-7-8-15(18)16(19)9-13/h7-9,11-12,14,17H,3-6,10H2,1-2H3/t11?,12?,14-,17-/m1/s1 JOQQHMGSIKNGAF-HLFYOVGASA-N 50026952 (cis) [3-(3,4-Dichloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]-dimethyl-amine(LR 5182)::CHEMBL322067::LR 5182::[(2R,3S)-3-(3,4-Dichloro-phenyl)-bicyclo[2.2.2]oct-2-ylmethyl]-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 570 PDSP Ki 10.1111/j.1471-4159.1985.tb08803.x 10.7270/Q27H1H2F 2580950 Hyttel, J; Larsen, JJ Lundbeck AIS http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44024 103936536 CHEMBL322067 ZINC38140594 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157269 CNCCC(Oc1ccccc1OC)c1ccccc1 InChI=1S/C17H21NO2/c1-18-13-12-15(14-8-4-3-5-9-14)20-17-11-7-6-10-16(17)19-2/h3-11,15,18H,12-13H2,1-2H3 ITJNARMNRKSWTA-UHFFFAOYSA-N 22417 3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine::CHEMBL295467::LY 135252::LY 94939::LY135252::LY139602::Nisoxetine::Nisoxetine Inhibitor::US9944618, Compound ID No. 177::[3-(2-methoxyphenoxy)-3-phenylpropyl](methyl)amine::[3H]Nisoxetine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1111/j.1471-4159.1985.tb08803.x 10.7270/Q27H1H2F 2580950 Hyttel, J; Larsen, JJ Lundbeck AIS http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22417&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 41U 4XNU 4500 49846232 73410 CHEMBL295467 DB09186 4637 ZINC01849597 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157270 CN1CC(c2ccccc2)c2cccc(N)c2C1 InChI=1S/C16H18N2/c1-18-10-14(12-6-3-2-4-7-12)13-8-5-9-16(17)15(13)11-18/h2-9,14H,10-11,17H2,1H3 XXPANQJNYNUNES-UHFFFAOYSA-N 50005548 (+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::(+/-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::(-)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::(Nomifensine) 2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine::2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine (Nomifensine)::2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine(Nomifensine)::2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine::CHEMBL273575::NOMIFENSINE::NOMIFENSINE2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-8-ylamine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1111/j.1471-4159.1985.tb08803.x 10.7270/Q27H1H2F 2580950 Hyttel, J; Larsen, JJ Lundbeck AIS http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4528 103919027 116225 CHEMBL273575 DB04821 4792 ZINC19796035 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157271 CNCCCC1(SC(C)(C)c2ccccc12)c1ccccc1 InChI=1S/C20H25NS/c1-19(2)17-12-7-8-13-18(17)20(22-19,14-9-15-21-3)16-10-5-4-6-11-16/h4-8,10-13,21H,9,14-15H2,1-3H3 FKHYYOUFMJBLAF-UHFFFAOYSA-N 50021217 CHEMBL52247::Talsupram::[3-(3,3-Dimethyl-1-phenyl-1,3-dihydro-benzo[c]thiophen-1-yl)-propyl]-methyl-amine(Talsupram) D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1111/j.1471-4159.1985.tb08803.x 10.7270/Q27H1H2F 2580950 Hyttel, J; Larsen, JJ Lundbeck AIS http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021217&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 33014 103931929 CHEMBL52247 DB09191 ZINC01999272 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156065 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.5 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156066 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.8 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156074 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Rattus norvegicus 2.4 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156076 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 576 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156079 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.8 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156083 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus 9560 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156087 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.069 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156090 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 9.2 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156091 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 4.8 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156092 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3N(CCCN3CCN(C)CC3)c2c1 InChI=1S/C22H30N4O2S2/c1-23(2)30(27,28)18-9-10-22-20(17-18)26(19-7-4-5-8-21(19)29-22)12-6-11-25-15-13-24(3)14-16-25/h4-5,7-10,17H,6,11-16H2,1-3H3 VZYCZNZBPPHOFY-UHFFFAOYSA-N 81793 CAS_316-81-4::NSC_92178::Thioproperazine D(2) dopamine receptor Rattus norvegicus 0.21 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81793&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9429 131342367 DB01622 ZINC22446685 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156093 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 3.3 PDSP Ki 10.1038/350610a0 10.7270/Q24T6GVD 1840645 Van Tol, HH; Bunzow, JR; Guan, HC; Sunahara, RK; Seeman, P; Niznik, HB; Civelli, O University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158657 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 27 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158658 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 3.1 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158659 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 12 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158660 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.7 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158661 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 211 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158662 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Rattus norvegicus 8.3 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158663 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 3.1 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158664 COc1ccc2Sc3ccccc3N(C[C@@H](C)CN(C)C)c2c1 InChI=1S/C19H24N2OS/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21/h5-11,14H,12-13H2,1-4H3/t14-/m0/s1 VRQVVMDWGGWHTJ-AWEZNQCLSA-N 50339137 CHEMBL1323355::Dextromepromazine::Levomepromazine D(2) dopamine receptor Rattus norvegicus 15 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50339137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50339137&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 165002 125089239 CHEMBL1323355 ZINC00057400 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158665 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 19 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158666 CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 UEQUQVLFIPOEMF-GOSISDBHSA-N 35256 (S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon D(2) dopamine receptor Rattus norvegicus 879 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154315 85753335 51137 ZINC00000855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158667 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) IENZQIKPVFGBNW-UHFFFAOYSA-N 29568 CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin D(2) dopamine receptor Rattus norvegicus 8786 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search XRA 3OWX 4893 81054997 8364 CHEMBL2 DB00457 503 C07368 ZINC00601304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158668 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.3 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158669 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 518 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158670 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 23 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158671 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(=O)(=O)CC InChI=1S/C17H26N2O4S/c1-4-19-10-6-7-13(19)12-18-17(20)15-11-14(24(21,22)5-2)8-9-16(15)23-3/h8-9,11,13H,4-7,10,12H2,1-3H3,(H,18,20)/t13-/m0/s1 UNRHXEPDKXPRTM-ZDUSSCGKSA-N 50019957 5-Ethanesulfonyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-benzamide((S)-sultopride)::CHEMBL278044::Sultopride D(2) dopamine receptor Rattus norvegicus 2.4 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 29010876 103930880 CHEMBL278044 C11708 ZINC00967922 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158672 CCN(CC)CCNC(=O)c1cc(ccc1OC)S(C)(=O)=O InChI=1S/C15H24N2O4S/c1-5-17(6-2)10-9-16-15(18)13-11-12(22(4,19)20)7-8-14(13)21-3/h7-8,11H,5-6,9-10H2,1-4H3,(H,16,18) JTVPZMFULRWINT-UHFFFAOYSA-N 82073 CAS_51012-32-9::NSC_5467::Tiapride D(2) dopamine receptor Rattus norvegicus 77 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82073&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5467 131342647 ZINC01542927 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158673 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 BLGXFZZNTVWLAY-SCYLSFHTSA-N 50013515 (+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester D(2) dopamine receptor Rattus norvegicus 158 PDSP Ki 10.1016/0006-8993(87)90040-0 10.7270/Q2T43RMR 3828800 Imafuku, J St, Marianna University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8969 103925641 48565 CHEMBL15245 DB01392 102 C09256 ZINC03860825 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156315 CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) NTJOBXMMWNYJFB-UHFFFAOYSA-N 81790 Amisulpride::CAS_71675-85-9::NSC_2159::US10167256, Amisulpride::US10259786, Amisulpride D(2) dopamine receptor Rattus norvegicus 1.7 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2159 131342364 64045 DB06288 963 ZINC01846088 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156316 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 24 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156317 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 5.3 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156318 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 2.8 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156319 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 56 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156320 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.3 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156321 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 474 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156322 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)NP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H17N6O13P3/c11-10-13-7-4(8(19)14-10)12-2-16(7)9-6(18)5(17)3(28-9)1-27-32(25,26)29-31(23,24)15-30(20,21)22/h2-3,5-6,9,17-18H,1H2,(H,25,26)(H3,11,13,14,19)(H4,15,20,21,22,23,24)/t3-,5-,6-,9-/m1/s1 UQABYHGXWYXDTK-UUOKFMHZSA-N 81791 Dopamine + GPP(NH)p::GPP(NH)P(+)::GPP(NH)p(-)::Guanylyl imidodiphosphate D(2) dopamine receptor Rattus norvegicus 1705 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 36735 131342365 C02058 ZINC37868676 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156323 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.45 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156324 CCS(=O)(=O)c1cc(C(=O)NCC2CCCN2CC2CC2)c(OC)cc1I InChI=1S/C19H27IN2O4S/c1-3-27(24,25)18-9-15(17(26-2)10-16(18)20)19(23)21-11-14-5-4-8-22(14)12-13-6-7-13/h9-10,13-14H,3-8,11-12H2,1-2H3,(H,21,23) QICCKJBXMXZXJQ-UHFFFAOYSA-N 81796 CAS_122245::Iodosulpride::NSC_122245 D(2) dopamine receptor Rattus norvegicus 0.61 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122245 131342370 ZINC14953439 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156325 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50028421 9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline; compound with methanesulfonic acid::CHEMBL1275::LY-127809::PERGOLIDE MESYLATE::Pergolide::Permax D(2) dopamine receptor Rattus norvegicus 21 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103937709 8021 CHEMBL1275 DB01186 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156326 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Rattus norvegicus 2.4 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156327 CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 WIKYUJGCLQQFNW-UHFFFAOYSA-N 78434 2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid::Compazine::Compro::MLS001148133::PROCHLORPERAZINE::SMR000653454::cid_91499 D(2) dopamine receptor Rattus norvegicus 4.7 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P77 3M0W 4917 252655190 8435 DB00433 C07403 ZINC19796018 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156328 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 576 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156329 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.8 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156330 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus 9560 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156331 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.06 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156332 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 85 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156333 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 9.2 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156334 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3N(CCCN3CCN(C)CC3)c2c1 InChI=1S/C22H30N4O2S2/c1-23(2)30(27,28)18-9-10-22-20(17-18)26(19-7-4-5-8-21(19)29-22)12-6-11-25-15-13-24(3)14-16-25/h4-5,7-10,17H,6,11-16H2,1-3H3 VZYCZNZBPPHOFY-UHFFFAOYSA-N 81793 CAS_316-81-4::NSC_92178::Thioproperazine D(2) dopamine receptor Rattus norvegicus 0.21 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81793&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9429 131342367 DB01622 ZINC22446685 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156335 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 3.3 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156336 C[NH+](C)C1CCc2cc(O)c(O)cc2C1 InChI=1S/C12H17NO2/c1-13(2)10-4-3-8-6-11(14)12(15)7-9(8)5-10/h6-7,10,14-15H,3-5H2,1-2H3/p+1 JWLJBTDXCBIGBW-UHFFFAOYSA-O 50025206 (6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dimethyl-ammonium::TL99 D(2) dopamine receptor Rattus norvegicus 18 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025206&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299913 103935110 ZINC05965207 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156337 CCCN(CCC)C1C=Cc2c(OC)cccc2C1C InChI=1S/C18H27NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-11,14,17H,5-6,12-13H2,1-4H3 YNNTVNSZMGTKJL-UHFFFAOYSA-N 81792 CAS_5311190::NSC_5311190::UH232::UH232(+) D(2) dopamine receptor Rattus norvegicus 40 PDSP Ki 10.1038/347146a0 10.7270/Q2CC0Z5N 1975644 Sokoloff, P; Giros, B; Martres, MP; Bouthenet, ML; Schwartz, JC U. 109 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54592327 131342366 ZINC14953308 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156380 C1CN(CCN1)c1cccc2OCCOc12 InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2 WVLHGCRWEHCIOT-UHFFFAOYSA-N 50035057 (eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine::1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine::CHEMBL282614::Eltoprazine D(2) dopamine receptor Rattus norvegicus 1100 PDSP Ki 10.1515/dmdi.1990.8.1-2.85 10.7270/Q27M06DV 1982626 Schipper, J; Tulp, MT; Sijbesma, H Duphar B.V. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035057&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65853 103943127 CHEMBL282614 ZINC00001347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157698 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 10 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157699 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(Br)c1OC InChI=1S/C15H20Br2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 JNFBCMWINGLNPB-VIFPVBQESA-N 50026053 3,5-Dibromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 36569::CHEMBL303334 D(2) dopamine receptor Rattus norvegicus 16 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033771 103935787 CHEMBL303334 ZINC26160354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157700 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)ccc1OC InChI=1S/C17H26N2O3/c1-4-12-8-9-14(22-3)15(16(12)20)17(21)18-11-13-7-6-10-19(13)5-2/h8-9,13,20H,4-7,10-11H2,1-3H3,(H,18,21)/t13-/m0/s1 YMTZSXGHAFKWEQ-ZDUSSCGKSA-N 50026059 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 37843::CHEMBL23403 D(2) dopamine receptor Rattus norvegicus 1.7 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026059&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55217 103935793 CHEMBL23403 ZINC05688578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157701 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Br)c1OC InChI=1S/C17H25BrN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 YKRGOSHQVJQEJE-LBPRGKRZSA-N 50026044 3-Bromo-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::A 37850::CHEMBL161668 D(2) dopamine receptor Rattus norvegicus 4.4 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10430157 103935778 CHEMBL161668 ZINC02021189 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157702 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 1.5 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157703 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 89 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157704 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.31 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157705 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.4 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157706 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 4.2 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157707 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 134 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157708 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Rattus norvegicus 2030 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157709 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 730 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157710 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 1 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157711 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 6.1 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157712 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 8 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157713 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(Br)c1OC InChI=1S/C15H20Br2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 JNFBCMWINGLNPB-VIFPVBQESA-N 50026053 3,5-Dibromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 36569::CHEMBL303334 D(2) dopamine receptor Rattus norvegicus 16 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033771 103935787 CHEMBL303334 ZINC26160354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157714 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(Br)c1OC InChI=1S/C15H20Br2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 JNFBCMWINGLNPB-VIFPVBQESA-N 50026053 3,5-Dibromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 36569::CHEMBL303334 D(2) dopamine receptor Rattus norvegicus 26 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033771 103935787 CHEMBL303334 ZINC26160354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157715 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)ccc1OC InChI=1S/C17H26N2O3/c1-4-12-8-9-14(22-3)15(16(12)20)17(21)18-11-13-7-6-10-19(13)5-2/h8-9,13,20H,4-7,10-11H2,1-3H3,(H,18,21)/t13-/m0/s1 YMTZSXGHAFKWEQ-ZDUSSCGKSA-N 50026059 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 37843::CHEMBL23403 D(2) dopamine receptor Rattus norvegicus 3.2 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026059&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55217 103935793 CHEMBL23403 ZINC05688578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157716 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)ccc1OC InChI=1S/C17H26N2O3/c1-4-12-8-9-14(22-3)15(16(12)20)17(21)18-11-13-7-6-10-19(13)5-2/h8-9,13,20H,4-7,10-11H2,1-3H3,(H,18,21)/t13-/m0/s1 YMTZSXGHAFKWEQ-ZDUSSCGKSA-N 50026059 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 37843::CHEMBL23403 D(2) dopamine receptor Rattus norvegicus 2.9 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026059&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55217 103935793 CHEMBL23403 ZINC05688578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157717 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Br)c1OC InChI=1S/C17H25BrN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 YKRGOSHQVJQEJE-LBPRGKRZSA-N 50026044 3-Bromo-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::A 37850::CHEMBL161668 D(2) dopamine receptor Rattus norvegicus 1 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10430157 103935778 CHEMBL161668 ZINC02021189 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157718 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Br)c1OC InChI=1S/C17H25BrN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 YKRGOSHQVJQEJE-LBPRGKRZSA-N 50026044 3-Bromo-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::A 37850::CHEMBL161668 D(2) dopamine receptor Rattus norvegicus 2.3 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10430157 103935778 CHEMBL161668 ZINC02021189 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157719 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(CC)c1OC InChI=1S/C19H30N2O3/c1-5-13-11-14(6-2)18(24-4)16(17(13)22)19(23)20-12-15-9-8-10-21(15)7-3/h11,15,22H,5-10,12H2,1-4H3,(H,20,23)/t15-/m0/s1 CLYMXDQVLPUPJD-HNNXBMFYSA-N 50026051 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Diethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 38120::CHEMBL62429 D(2) dopamine receptor Rattus norvegicus 1.5 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55901 103935785 CHEMBL62429 ZINC05688553 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157720 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(CC)c1OC InChI=1S/C19H30N2O3/c1-5-13-11-14(6-2)18(24-4)16(17(13)22)19(23)20-12-15-9-8-10-21(15)7-3/h11,15,22H,5-10,12H2,1-4H3,(H,20,23)/t15-/m0/s1 CLYMXDQVLPUPJD-HNNXBMFYSA-N 50026051 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Diethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 38120::CHEMBL62429 D(2) dopamine receptor Rattus norvegicus 1.8 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55901 103935785 CHEMBL62429 ZINC05688553 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157721 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 41 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157722 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 17 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157723 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 1490 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157724 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 433 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157725 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.6 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157726 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.92 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157727 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 5.5 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157728 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 12 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157729 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 205 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157730 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 235 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157731 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 26 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157732 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 32 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157733 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Rattus norvegicus 1640 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157734 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Rattus norvegicus 1570 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157735 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 122 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157736 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 233 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155227 NC1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2 ASXGAOFCKGHGMF-UHFFFAOYSA-N 81195 (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide::2-aminotetralin-6,7-diol;hydrobromide::6-Amino-5,6,7,8-tetrahydro-naphthalene-2,3-diol::6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::6-azanyl-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::ADTN::ADTN, (+)::CA inhibitor, 3::CHEMBL26736::MLS002172466::SMR001254097::cid_11957526::cid_3153 D(2) dopamine receptor Rattus norvegicus 6.1 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3153 252657735 CHEMBL26736 ZINC03872370 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155228 NC1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2 ASXGAOFCKGHGMF-UHFFFAOYSA-N 81195 (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide::2-aminotetralin-6,7-diol;hydrobromide::6-Amino-5,6,7,8-tetrahydro-naphthalene-2,3-diol::6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::6-azanyl-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::ADTN::ADTN, (+)::CA inhibitor, 3::CHEMBL26736::MLS002172466::SMR001254097::cid_11957526::cid_3153 D(2) dopamine receptor Rattus norvegicus 24 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3153 252657735 CHEMBL26736 ZINC03872370 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155229 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 15 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155230 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 83 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155231 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 54 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155232 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155233 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 16 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155234 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 7 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155235 CN(C)CCCSc1ccccc1NC(=O)\C=C\c1ccccc1 InChI=1S/C20H24N2OS/c1-22(2)15-8-16-24-19-12-7-6-11-18(19)21-20(23)14-13-17-9-4-3-5-10-17/h3-7,9-14H,8,15-16H2,1-2H3,(H,21,23)/b14-13+ RSUVYMGADVXGOU-BUHFOSPRSA-N 50016900 (E)-N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-3-phenyl-acrylamide::CHEMBL18786::CINANSERIN::N-(2-(3-(dimethylamino)propylthio)phenyl)cinnamamide::N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-3-phenyl-acrylamide::N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-3-phenyl-acrylamide (cinanserin)::N-[2-(3-Dimethylamino-propylsulfanyl)-phenyl]-3-phenyl-acrylamide(Cinanserin)::acs.jmedchem.1c00409_ST.370 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016900&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5475158 103928234 CHEMBL18786 ZINC01714738 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155236 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 608 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155237 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 253 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155238 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 594 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155239 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 51 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155240 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 23 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155241 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 7.9 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155242 OC(=O)c1ccccc1C(=O)Nc1cccc2ccccc12 InChI=1S/C18H13NO3/c20-17(14-9-3-4-10-15(14)18(21)22)19-16-11-5-7-12-6-1-2-8-13(12)16/h1-11H,(H,19,20)(H,21,22) JXTHEWSKYLZVJC-UHFFFAOYSA-N 81777 CAS_132-66-1::NPA::NPA,(+)::NPA,(-)::NSC_8594 D(2) dopamine receptor Rattus norvegicus 4.8 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E7O 7QPC,7WKW,7Y9U 8594 131342351 60833 C06374 ZINC00028113 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155243 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 8 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155244 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 24 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155245 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 2367 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155246 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 5560 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155247 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus 1621 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155248 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 6.6 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155249 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155250 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 636 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155251 CCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1 BGRJTUBHPOOWDU-LLVKDONJSA-N 81775 Sulpiride-R::Sulpiride-d::Sulpiride-high,(-)::Sulpiride-low,(-) D(2) dopamine receptor Rattus norvegicus 329 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 643497 131342349 64122 960 ZINC00020229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155252 CCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1 BGRJTUBHPOOWDU-LLVKDONJSA-N 81775 Sulpiride-R::Sulpiride-d::Sulpiride-high,(-)::Sulpiride-low,(-) D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.7270/Q2RR1WQK 1356154 Levant, B; Grigoriadis, DE; DeSouza, EB DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 643497 131342349 64122 960 ZINC00020229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155274 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1cccc2ccoc12 InChI=1S/C19H18ClNO2/c1-21-7-5-13-9-17(20)18(22)10-15(13)16(11-21)14-4-2-3-12-6-8-23-19(12)14/h2-4,6,8-10,16,22H,5,7,11H2,1H3/t16-/m1/s1 RUSANBIFMAXXSJ-MRXNPFEDSA-N 50010709 5-Benzofuran-7-yl-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL71600::NNC-112::NNC-112,(-) D(2) dopamine receptor Rattus norvegicus 898 PDSP Ki 10.1016/0014-2999(92)90578-r 10.7270/Q2H70D9P 1397049 Andersen, PH; Gronvald, FC; Hohlweg, R; Hansen, LB; Guddal, E; Braestrup, C; Nielsen, EB Novo Nordisk http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010709&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130424 103923455 CHEMBL71600 ZINC05966869 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157737 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 57 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 157738 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 67 PDSP Ki 10.1111/j.1600-0773.1986.tb00071.x 10.7270/Q2PG1Q7V 2869639 Hall, H; Sallemark, M; Jerning, E Astra Läkemedel AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155275 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1cccc2ccoc12 InChI=1S/C19H18ClNO2/c1-21-7-5-13-9-17(20)18(22)10-15(13)16(11-21)14-4-2-3-12-6-8-23-19(12)14/h2-4,6,8-10,16,22H,5,7,11H2,1H3/t16-/m1/s1 RUSANBIFMAXXSJ-MRXNPFEDSA-N 50010709 5-Benzofuran-7-yl-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL71600::NNC-112::NNC-112,(-) D(2) dopamine receptor Rattus norvegicus 988 PDSP Ki 10.1016/0014-2999(92)90578-r 10.7270/Q2H70D9P 1397049 Andersen, PH; Gronvald, FC; Hohlweg, R; Hansen, LB; Guddal, E; Braestrup, C; Nielsen, EB Novo Nordisk http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010709&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130424 103923455 CHEMBL71600 ZINC05966869 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155276 CN1CCc2cc(c(O)cc2C(C1)c1cccc2CCOc12)[N+]([O-])=O InChI=1S/C19H20N2O4/c1-20-7-5-13-9-17(21(23)24)18(22)10-15(13)16(11-20)14-4-2-3-12-6-8-25-19(12)14/h2-4,9-10,16,22H,5-8,11H2,1H3 XZPSYCOYKJRHKE-UHFFFAOYSA-N 81779 CAS_164252::NNC-687::NSC_164252 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0014-2999(92)90578-r 10.7270/Q2H70D9P 1397049 Andersen, PH; Gronvald, FC; Hohlweg, R; Hansen, LB; Guddal, E; Braestrup, C; Nielsen, EB Novo Nordisk http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81779&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840885 131342353 ZINC31476325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155277 CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc2CCOc12 InChI=1S/C19H20ClNO2/c1-21-7-5-13-9-17(20)18(22)10-15(13)16(11-21)14-4-2-3-12-6-8-23-19(12)14/h2-4,9-10,16,22H,5-8,11H2,1H3 SKMVRXPBCSTNKE-UHFFFAOYSA-N 81778 CAS_132421::NNC-756::NSC_132421 D(2) dopamine receptor Rattus norvegicus 942 PDSP Ki 10.1016/0014-2999(92)90578-r 10.7270/Q2H70D9P 1397049 Andersen, PH; Gronvald, FC; Hohlweg, R; Hansen, LB; Guddal, E; Braestrup, C; Nielsen, EB Novo Nordisk http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14958952 131342352 ZINC03781602 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155278 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 900 PDSP Ki 10.1016/0014-2999(92)90578-r 10.7270/Q2H70D9P 1397049 Andersen, PH; Gronvald, FC; Hohlweg, R; Hansen, LB; Guddal, E; Braestrup, C; Nielsen, EB Novo Nordisk http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155279 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 895 PDSP Ki 10.1016/0014-2999(92)90578-r 10.7270/Q2H70D9P 1397049 Andersen, PH; Gronvald, FC; Hohlweg, R; Hansen, LB; Guddal, E; Braestrup, C; Nielsen, EB Novo Nordisk http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155280 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus 9300 PDSP Ki 10.1016/0014-2999(92)90578-r 10.7270/Q2H70D9P 1397049 Andersen, PH; Gronvald, FC; Hohlweg, R; Hansen, LB; Guddal, E; Braestrup, C; Nielsen, EB Novo Nordisk http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155307 CN(C)CCON=C(C=Cc1ccc(O)cc1)c1ccccc1F InChI=1S/C19H21FN2O2/c1-22(2)13-14-24-21-19(17-5-3-4-6-18(17)20)12-9-15-7-10-16(23)11-8-15/h3-12,23H,13-14H2,1-2H3 VAIOZOCLKVMIMN-UHFFFAOYSA-N 81780 CAS_6438382::NSC_6438382::SR 46349B D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.7270/Q27S7M7Z 1501121 Rinaldi-Carmona, M; Congy, C; Santucci, V; Simiand, J; Gautret, B; Neliat, G; Labeeuw, B; Le Fur, G; Soubrie, P; Breliere, JC Sanofi Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81780&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5486684 131342354 ZINC14953472 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156596 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 8912.5 PDSP Ki 10.7270/Q26M359X 2017157 Neve, KA Medical Research Service http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156699 Nc1cc(Cl)c(NC2=NCCN2)c(Cl)c1 InChI=1S/C9H10Cl2N4/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2,12H2,(H2,13,14,15) IEJXVRYNEISIKR-UHFFFAOYSA-N 81926 Aminoclonidine, p::CAS_66711-21-5::NSC_51763::p-AMINOCLONIDINE D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81926&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2216 131342500 2789 DB00964 C07668 ZINC00057175 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156700 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 2.5 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156701 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 2 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156702 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 2.2 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156703 Clc1cccc(Cl)c1N=C1NCCN1 InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14) GJSURZIOUXUGAL-UHFFFAOYSA-N 50016897 2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form) D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search CLU 2PNC,7AWW 2803 103928231 46632 516 ZINC00896484 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156704 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 5.4 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156705 C1CN=C(N1)C1COc2ccccc2O1 InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) HPMRFMKYPGXPEP-UHFFFAOYSA-N 50019848 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54459 103930771 5862 CHEMBL10316 C10968 ZINC00900630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156706 CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 UEQUQVLFIPOEMF-GOSISDBHSA-N 35256 (S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon D(2) dopamine receptor Rattus norvegicus 3200 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154315 85753335 51137 ZINC00000855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156707 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.11 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156708 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.1 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156709 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.12 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156710 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 23 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156711 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 42 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156712 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 42 PDSP Ki 10.7270/Q2TD9VV5 2138666 Neve, KA; Henningsen, RA; Kinzie, JM; De Paulis, T; Schmidt, DE; Kessler, RM; Janowsky, A Department of Veterans Affairs Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156946 c1ccccc1 InChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H UHOVQNZJYSORNB-UHFFFAOYSA-N 50167939 3,4-DNH::5-Hydroxy Tryptamine::BM 613::Benzen::Benzine::Benzol::Bicarburet of hydrogen::CHEMBL277500::Cc-34,(+/-)::Coal naphtha::Mineral naphtha::Phene::Pyrobenzol::Pyrobenzole::[6]annulene::benzene::benzole::cyclohexatriene::erythro-Phenyl-2-piperidyl-carbinol,(-)::phenyl hydride::trans-N, N-Dimethylphenylcyclopropylamine::trans-N-Methylphenylcyclopropylamine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SBC 2BKZ 241 104053118 16716 CHEMBL277500 C01407 ZINC00967532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156947 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156948 NC1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2 ASXGAOFCKGHGMF-UHFFFAOYSA-N 81195 (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide::2-aminotetralin-6,7-diol;hydrobromide::6-Amino-5,6,7,8-tetrahydro-naphthalene-2,3-diol::6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::6-azanyl-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::ADTN::ADTN, (+)::CA inhibitor, 3::CHEMBL26736::MLS002172466::SMR001254097::cid_11957526::cid_3153 D(2) dopamine receptor Rattus norvegicus 1370 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3153 252657735 CHEMBL26736 ZINC03872370 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156949 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 98 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156950 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 6700 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156951 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 0.9 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156952 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 4.6 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156953 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 90 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156954 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.72 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156955 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 660 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156956 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Rattus norvegicus 0.34 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156957 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Rattus norvegicus 100 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156958 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Rattus norvegicus 0.84 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156959 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2.6 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156960 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 400 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156961 CCCN1CCCC2Cc3[nH]ncc3CC12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15) FTSUPYGMFAPCFZ-UHFFFAOYSA-N 81873 CAS_55397::LY-171555::NSC_55397::QUINPIROLE D(2) dopamine receptor Rattus norvegicus 720 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81873&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1257 131342447 ZINC08584336 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156962 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50028421 9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline; compound with methanesulfonic acid::CHEMBL1275::LY-127809::PERGOLIDE MESYLATE::Pergolide::Permax D(2) dopamine receptor Rattus norvegicus 7.8 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103937709 8021 CHEMBL1275 DB01186 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156963 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 RGCVKNLCSQQDEP-UHFFFAOYSA-N 50130273 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine D(2) dopamine receptor Rattus norvegicus 0.95 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4748 104021707 8028 CHEMBL567 DB00850 209 C07427 ZINC19228902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156964 N1c2ccccc2Sc2ccccc12 InChI=1S/C12H9NS/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H WJFKNYWRSNBZNX-UHFFFAOYSA-N 50012855 10H-Phenothiazin::10H-phenothiazine::CHEMBL828::cid_7108::dibenzo-1,4-thiazine::phenothiazine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7108 103925105 37931 CHEMBL828 ZINC00028150 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156965 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Rattus norvegicus 0.38 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156966 CC(CN1c2ccccc2Sc2ccccc12)N(C)C InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3 PWWVAXIEGOYWEE-UHFFFAOYSA-N 50017696 (2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine::10-(2-Dimethylaminopropyl)phenothiazine::10-[2-(dimethylamino)propyl]phenothiazine::CHEMBL643::N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine::N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine::PROMETHAZINE::med.21724, Compound 16::proazamine D(2) dopamine receptor Rattus norvegicus 260 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017696&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ZM7 7MQU 4927 103928964 8461 CHEMBL643 DB01069 7282 C07404 ZINC00056647 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156967 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 895 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156968 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus 9300 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158145 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 3.6 PDSP Ki 10.7270/Q2NK3CHS 2905002 Chipkin, RE; Iorio, LC; Coffin, VL; McQuade, RD; Berger, JG; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158146 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 359 PDSP Ki 10.7270/Q2NK3CHS 2905002 Chipkin, RE; Iorio, LC; Coffin, VL; McQuade, RD; Berger, JG; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158147 CN1CCc2cc(Cl)c(O)cc2[C@@H]2[C@@H]1CCc1ccccc21 InChI=1S/C19H20ClNO/c1-21-9-8-13-10-16(20)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-17(19)21/h2-5,10-11,17,19,22H,6-9H2,1H3/t17-,19+/m0/s1 DMJWENQHWZZWDF-PKOBYXMFSA-N 50004823 (6aS,13bR)-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::(6aS,13bR)-11-chloro-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol::11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL298406::Ecopipam::SCH 39166::trans-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol D(2) dopamine receptor Rattus norvegicus 4268 PDSP Ki 10.7270/Q2NK3CHS 2905002 Chipkin, RE; Iorio, LC; Coffin, VL; McQuade, RD; Berger, JG; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 107930 103918370 CHEMBL298406 3304 ZINC00003897 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158148 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 0.8 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158149 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 0.8 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158150 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 0.3 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158151 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 0.7 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158152 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.3 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158153 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158154 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/p-1/t3-,5-,6-,9-/m1/s1 XKMLYUALXHKNFT-UUOKFMHZSA-M 81874 Dopamine+ (GTP+)::Dopamine+GTP::NPA+ (GTP+) D(2) dopamine receptor Rattus norvegicus 5300 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91898390 131342448 15996 C03517 ZINC60094177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158155 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/p-1/t3-,5-,6-,9-/m1/s1 XKMLYUALXHKNFT-UUOKFMHZSA-M 81874 Dopamine+ (GTP+)::Dopamine+GTP::NPA+ (GTP+) D(2) dopamine receptor Rattus norvegicus 9000 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91898390 131342448 15996 C03517 ZINC60094177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158156 Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/p-1/t3-,5-,6-,9+/m1/s1 XKMLYUALXHKNFT-BDXYJKHTSA-M 81995 Dopamine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 2900 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91898396 131342569 C03517 ZINC49767488 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158157 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 300 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158158 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 490 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158159 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/p-1/t3-,5-,6-,9-/m1/s1 XKMLYUALXHKNFT-UUOKFMHZSA-M 81874 Dopamine+ (GTP+)::Dopamine+GTP::NPA+ (GTP+) D(2) dopamine receptor Rattus norvegicus 6.5 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91898390 131342448 15996 C03517 ZINC60094177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158160 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/p-1/t3-,5-,6-,9-/m1/s1 XKMLYUALXHKNFT-UUOKFMHZSA-M 81874 Dopamine+ (GTP+)::Dopamine+GTP::NPA+ (GTP+) D(2) dopamine receptor Rattus norvegicus 18 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91898390 131342448 15996 C03517 ZINC60094177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158161 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 24 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 158162 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 70 PDSP Ki 10.7270/Q2HT2MTH 2958621 Lin, C; McGonigle, P; Molinoff, PB University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155742 NC(=N)NC(=O)c1nc(Cl)c(N)nc1N InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15) XSDQTOBWRPYKKA-UHFFFAOYSA-N 16173 3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinamide;hydrochloride::3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide::Amiloride::Amipramidin::CHEMBL945 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.3109/10799899109064686 10.7270/Q2TH8K5J 1661335 Garritsen, A; Ijzerman, AP; Tulp, MT; Cragoe, EJ; Soudijn, W Center for Bio-Pharmaceutical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search AMR 4NTX,1F5L 16231 46516430 2639 CHEMBL945 2421 C06821 ZINC04340269 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155743 NC(NC(=O)c1nc(Cl)c(N)nc1N)=NCc1ccccc1 InChI=1S/C13H14ClN7O/c14-9-11(16)20-10(15)8(19-9)12(22)21-13(17)18-6-7-4-2-1-3-5-7/h1-5H,6H2,(H4,15,16,20)(H3,17,18,21,22) KXDROGADUISDGY-UHFFFAOYSA-N 81819 Benzamil::CAS_1937-37-7::CHEMBL212579::NSC_108107 D(2) dopamine receptor Rattus norvegicus 7600 PDSP Ki 10.3109/10799899109064686 10.7270/Q2TH8K5J 1661335 Garritsen, A; Ijzerman, AP; Tulp, MT; Cragoe, EJ; Soudijn, W Center for Bio-Pharmaceutical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 108107 131342393 CHEMBL212579 4145 ZINC13548421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 155744 NC(=N)NC(=O)c1nc(Cl)c(nc1N)N1CCCCCC1 InChI=1S/C12H18ClN7O/c13-8-10(20-5-3-1-2-4-6-20)18-9(14)7(17-8)11(21)19-12(15)16/h1-6H2,(H2,14,18)(H4,15,16,19,21) RQQJJXVETXFINY-UHFFFAOYSA-N 81818 CAS_1794::CHEMBL1909810::HMA::NSC_1794 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.3109/10799899109064686 10.7270/Q2TH8K5J 1661335 Garritsen, A; Ijzerman, AP; Tulp, MT; Cragoe, EJ; Soudijn, W Center for Bio-Pharmaceutical Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1794 131342392 CHEMBL1909810 1192 ZINC03871091 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156969 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.11 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156970 CCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1 BGRJTUBHPOOWDU-LLVKDONJSA-N 81775 Sulpiride-R::Sulpiride-d::Sulpiride-high,(-)::Sulpiride-low,(-) D(2) dopamine receptor Rattus norvegicus 1300 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 643497 131342349 64122 960 ZINC00020229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156971 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 34 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156972 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 9.5 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 156973 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1 InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8- GFBKORZTTCHDGY-UWVJOHFNSA-N 78576 CIS-THIOTHIXENE::MLS000028463::SMR000058396::THIOTHIXENE::cid_941651::med.21724, Compound Thiothixene D(2) dopamine receptor Rattus norvegicus 0.66 PDSP Ki 10.1016/0024-3205(85)90028-1 10.7270/Q2HX1B5B 2415793 Andersen, PH; Gronvald, FC; Jansen, JA Université Catholique de Louvain http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941651 252655323 DB01623 212 ZINC30690433 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163406 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT D(2) dopamine receptor Rattus norvegicus 7950 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163407 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163408 CC(C)NCC(O)COc1ccccc1CC=C InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3 PAZJSJFMUHDSTF-UHFFFAOYSA-N 25764 ALPRENOLOL,(+)::ALPRENOLOL,(-)::Alfeprol::Alpheprol::Alprenolol::CHEMBL266195::{2-hydroxy-3-[2-(prop-2-en-1-yl)phenoxy]propyl}(propan-2-yl)amine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search JTZ 3NYA,6OBA,6PS2,6PRZ 2119 56413052 51211 CHEMBL266195 DB00866 563 ZINC00086599 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163409 CC(C)NCC(O)COc1ccccc1CC=C InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3 PAZJSJFMUHDSTF-UHFFFAOYSA-N 25764 ALPRENOLOL,(+)::ALPRENOLOL,(-)::Alfeprol::Alpheprol::Alprenolol::CHEMBL266195::{2-hydroxy-3-[2-(prop-2-en-1-yl)phenoxy]propyl}(propan-2-yl)amine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search JTZ 3NYA,6OBA,6PS2,6PRZ 2119 56413052 51211 CHEMBL266195 DB00866 563 ZINC00086599 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163410 CC(C)NCC(O)COc1ccccc1CC=C InChI=1S/C15H23NO2/c1-4-7-13-8-5-6-9-15(13)18-11-14(17)10-16-12(2)3/h4-6,8-9,12,14,16-17H,1,7,10-11H2,2-3H3 PAZJSJFMUHDSTF-UHFFFAOYSA-N 25764 ALPRENOLOL,(+)::ALPRENOLOL,(-)::Alfeprol::Alpheprol::Alprenolol::CHEMBL266195::{2-hydroxy-3-[2-(prop-2-en-1-yl)phenoxy]propyl}(propan-2-yl)amine D(2) dopamine receptor Rattus norvegicus 6860 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search JTZ 3NYA,6OBA,6PS2,6PRZ 2119 56413052 51211 CHEMBL266195 DB00866 563 ZINC00086599 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163411 CC(C)NCC(O)COc1ccc(CC(N)=O)cc1 InChI=1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18) METKIMKYRPQLGS-UHFFFAOYSA-N 25753 2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide::Artrenolol::Atenolol::CHEMBL24::Tenormin::Tenormine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25753&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2TN 2NUV,2OTF,2OUB 2249 56413041 2904 CHEMBL24 DB00335 548 ZINC00113415 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163412 CN1CCc2cc3OCOc3cc2[C@H]1[C@@H]1OC(=O)c2c1ccc1OCOc21 InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1 IYGYMKDQCDOMRE-ZWKOTPCHSA-N 50000693 (R)-6-((S)-6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one::(R)-6-((S)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuro[5,4-d][1,3]dioxol-8(6H)-one::(bicuculline) 6-Methyl-5-(8-oxo-6,8-dihydro-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium::6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one::6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one (Bicuculline)::6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one(bicuculline)::Bicuculline,(+)::CHEMBL417990::bicuculline D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search H0Z 6HUK 10237 103915241 3092 CHEMBL417990 2312 C09364 ZINC19899011 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163413 CN1CCc2cc3OCOc3cc2[C@H]1[C@@H]1OC(=O)c2c1ccc1OCOc21 InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1 IYGYMKDQCDOMRE-ZWKOTPCHSA-N 50000693 (R)-6-((S)-6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one::(R)-6-((S)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuro[5,4-d][1,3]dioxol-8(6H)-one::(bicuculline) 6-Methyl-5-(8-oxo-6,8-dihydro-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium::6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one::6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one (Bicuculline)::6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one(bicuculline)::Bicuculline,(+)::CHEMBL417990::bicuculline D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search H0Z 6HUK 10237 103915241 3092 CHEMBL417990 2312 C09364 ZINC19899011 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163414 CN1CCc2cc3OCOc3cc2[C@H]1[C@@H]1OC(=O)c2c1ccc1OCOc21 InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18H,4-5,8-9H2,1H3/t17-,18+/m0/s1 IYGYMKDQCDOMRE-ZWKOTPCHSA-N 50000693 (R)-6-((S)-6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one::(R)-6-((S)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)isobenzofuro[5,4-d][1,3]dioxol-8(6H)-one::(bicuculline) 6-Methyl-5-(8-oxo-6,8-dihydro-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-6-yl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium::6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one::6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one (Bicuculline)::6-(6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6H-furo[3',4':3,4]benzo[1,2-d][1,3]dioxol-8-one(bicuculline)::Bicuculline,(+)::CHEMBL417990::bicuculline D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search H0Z 6HUK 10237 103915241 3092 CHEMBL417990 2312 C09364 ZINC19899011 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163415 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.28 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163416 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.34 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163417 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.53 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163418 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor Rattus norvegicus 0.1 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163419 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor Rattus norvegicus 0.12 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163420 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor Rattus norvegicus 0.1 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163421 C1CN=C(N1)C1COc2ccccc2O1 InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) HPMRFMKYPGXPEP-UHFFFAOYSA-N 50019848 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54459 103930771 5862 CHEMBL10316 C10968 ZINC00900630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163422 C1CN=C(N1)C1COc2ccccc2O1 InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) HPMRFMKYPGXPEP-UHFFFAOYSA-N 50019848 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54459 103930771 5862 CHEMBL10316 C10968 ZINC00900630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163423 C1CN=C(N1)C1COc2ccccc2O1 InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) HPMRFMKYPGXPEP-UHFFFAOYSA-N 50019848 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54459 103930771 5862 CHEMBL10316 C10968 ZINC00900630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163424 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 583 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163425 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 555 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163426 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 519 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163427 CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 UEQUQVLFIPOEMF-GOSISDBHSA-N 35256 (S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon D(2) dopamine receptor Rattus norvegicus 1690 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154315 85753335 51137 ZINC00000855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163428 CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 UEQUQVLFIPOEMF-GOSISDBHSA-N 35256 (S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon D(2) dopamine receptor Rattus norvegicus 674 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154315 85753335 51137 ZINC00000855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163429 CN1CCN2[C@H](C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1 UEQUQVLFIPOEMF-GOSISDBHSA-N 35256 (S)-mianserin::Lerivon::MIANSERIN::MIANSERIN (+)::MIANSERIN (-)::Tolvon D(2) dopamine receptor Rattus norvegicus 1700 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154315 85753335 51137 ZINC00000855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163430 NCc1cc(=O)[nH]o1 InChI=1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7) ZJQHPWUVQPJPQT-UHFFFAOYSA-N 23183 5-(aminomethyl)-1,2-oxazol-3-ol::Agarin::CHEMBL273481::Muscimol::Pantherine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4266 49846996 CHEMBL273481 4259 C08311 ZINC22064260 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163431 NCc1cc(=O)[nH]o1 InChI=1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7) ZJQHPWUVQPJPQT-UHFFFAOYSA-N 23183 5-(aminomethyl)-1,2-oxazol-3-ol::Agarin::CHEMBL273481::Muscimol::Pantherine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4266 49846996 CHEMBL273481 4259 C08311 ZINC22064260 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163432 NCc1cc(=O)[nH]o1 InChI=1S/C4H6N2O2/c5-2-3-1-4(7)6-8-3/h1H,2,5H2,(H,6,7) ZJQHPWUVQPJPQT-UHFFFAOYSA-N 23183 5-(aminomethyl)-1,2-oxazol-3-ol::Agarin::CHEMBL273481::Muscimol::Pantherine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4266 49846996 CHEMBL273481 4259 C08311 ZINC22064260 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163433 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163434 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163435 Oc1ccc2C[C@H]3N(CC=C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O InChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1 UZHSEJADLWPNLE-GRGSLBFTSA-N 50000788 (morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol::(naloxone) 4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::(naloxone)4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one (naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one( Naloxone)::4-allyl-10,17-dihydroxy-(1S,5R,13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(Naxolone)::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one::4-allyl-10,17-dihydroxy-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(naloxone)C2H2O4::Analog of 14-(Arylhydroxyamino)codeinone::NALOXONE::NARCAN::SUBOXONE::[17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydroxymorphinan-6-one D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000788&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5284596 103915330 7459 DB01183 1676 C07252 ZINC00389747 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163436 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) IENZQIKPVFGBNW-UHFFFAOYSA-N 29568 CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search XRA 3OWX 4893 81054997 8364 CHEMBL2 DB00457 503 C07368 ZINC00601304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163437 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) IENZQIKPVFGBNW-UHFFFAOYSA-N 29568 CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search XRA 3OWX 4893 81054997 8364 CHEMBL2 DB00457 503 C07368 ZINC00601304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163438 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) IENZQIKPVFGBNW-UHFFFAOYSA-N 29568 CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search XRA 3OWX 4893 81054997 8364 CHEMBL2 DB00457 503 C07368 ZINC00601304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163439 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 930 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163440 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 389 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163441 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 734 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163442 OC(=O)C(O)(c1ccccc1)c1ccccc1 InChI=1S/C14H12O3/c15-13(16)14(17,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,17H,(H,15,16) UKXSKSHDVLQNKG-UHFFFAOYSA-N 81768 BENZYLIC ACID::CAS_6581-06-2::NSC_5311391::Quinuclidinyl benzilate D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81768&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 0UT 4HNC 6463 131342342 ZINC06645452 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163443 OC(=O)C(O)(c1ccccc1)c1ccccc1 InChI=1S/C14H12O3/c15-13(16)14(17,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,17H,(H,15,16) UKXSKSHDVLQNKG-UHFFFAOYSA-N 81768 BENZYLIC ACID::CAS_6581-06-2::NSC_5311391::Quinuclidinyl benzilate D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81768&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 0UT 4HNC 6463 131342342 ZINC06645452 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163444 OC(=O)C(O)(c1ccccc1)c1ccccc1 InChI=1S/C14H12O3/c15-13(16)14(17,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,17H,(H,15,16) UKXSKSHDVLQNKG-UHFFFAOYSA-N 81768 BENZYLIC ACID::CAS_6581-06-2::NSC_5311391::Quinuclidinyl benzilate D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81768&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 0UT 4HNC 6463 131342342 ZINC06645452 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163445 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 4650 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163446 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C InChI=1S/C17H23NO/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17/h4-6,11-12,16,19H,1,7-10H2,2-3H3/t12-,16+,17-/m0/s1 LGQCVMYAEFTEFN-VUCTXSBTSA-N 50001031 3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL330376::SKF 10,047 (+)::SKF 10,047 (-)::SKF 10047 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44330991 103915564 CHEMBL330376 ZINC00000523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163447 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C InChI=1S/C17H23NO/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17/h4-6,11-12,16,19H,1,7-10H2,2-3H3/t12-,16+,17-/m0/s1 LGQCVMYAEFTEFN-VUCTXSBTSA-N 50001031 3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL330376::SKF 10,047 (+)::SKF 10,047 (-)::SKF 10047 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44330991 103915564 CHEMBL330376 ZINC00000523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163448 C[C@H]1[C@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C InChI=1S/C17H23NO/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17/h4-6,11-12,16,19H,1,7-10H2,2-3H3/t12-,16+,17-/m0/s1 LGQCVMYAEFTEFN-VUCTXSBTSA-N 50001031 3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL330376::SKF 10,047 (+)::SKF 10,047 (-)::SKF 10047 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44330991 103915564 CHEMBL330376 ZINC00000523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163449 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.05 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163450 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.04 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163451 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.06 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163452 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 8.2 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163453 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 10.2 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163454 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 10.5 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163455 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1cc(Cl)cc(Cl)c1 InChI=1S/C15H17Cl2NO2/c1-18-12-2-3-13(18)8-14(7-12)20-15(19)9-4-10(16)6-11(17)5-9/h4-6,12-14H,2-3,7-8H2,1H3/t12-,13+,14+ MNJNPLVXBISNSX-WDNDVIMCSA-N 82561 CAS_40796-97-2::TROPANYL 3,5-DICHLOROBENZOATE::Tropanyl-3,5 dichlorobenzoate D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 671690 136350531 C02089 ZINC00033131 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163456 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1cc(Cl)cc(Cl)c1 InChI=1S/C15H17Cl2NO2/c1-18-12-2-3-13(18)8-14(7-12)20-15(19)9-4-10(16)6-11(17)5-9/h4-6,12-14H,2-3,7-8H2,1H3/t12-,13+,14+ MNJNPLVXBISNSX-WDNDVIMCSA-N 82561 CAS_40796-97-2::TROPANYL 3,5-DICHLOROBENZOATE::Tropanyl-3,5 dichlorobenzoate D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 671690 136350531 C02089 ZINC00033131 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 163457 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1cc(Cl)cc(Cl)c1 InChI=1S/C15H17Cl2NO2/c1-18-12-2-3-13(18)8-14(7-12)20-15(19)9-4-10(16)6-11(17)5-9/h4-6,12-14H,2-3,7-8H2,1H3/t12-,13+,14+ MNJNPLVXBISNSX-WDNDVIMCSA-N 82561 CAS_40796-97-2::TROPANYL 3,5-DICHLOROBENZOATE::Tropanyl-3,5 dichlorobenzoate D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/syn.890150302 10.7270/Q2MS3R8Z 8278895 Kessler, RM; Votaw, JR; de Paulis, T; Bingham, DR; Ansari, MS; Mason, NS; Holburn, G; Schmidt, DE; Votaw, DB; Manning, RG Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 671690 136350531 C02089 ZINC00033131 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159771 Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3 PMXMIIMHBWHSKN-UHFFFAOYSA-N 50252513 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE D(2) dopamine receptor Rattus norvegicus 3.5 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search K4I 115237 104105311 CHEMBL1621 DB01267 7258 ZINC04214700 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159772 Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3 PMXMIIMHBWHSKN-UHFFFAOYSA-N 50252513 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE D(2) dopamine receptor Rattus norvegicus 3.9 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search K4I 115237 104105311 CHEMBL1621 DB01267 7258 ZINC04214700 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159773 Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3 PMXMIIMHBWHSKN-UHFFFAOYSA-N 50252513 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE D(2) dopamine receptor Rattus norvegicus 6.7 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search K4I 115237 104105311 CHEMBL1621 DB01267 7258 ZINC04214700 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159774 Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3 PMXMIIMHBWHSKN-UHFFFAOYSA-N 50252513 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE D(2) dopamine receptor Rattus norvegicus 4.6 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search K4I 115237 104105311 CHEMBL1621 DB01267 7258 ZINC04214700 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159775 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 73 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159776 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 102 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159777 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 99 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159778 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 152 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159779 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.5 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159780 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.65 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159781 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.7 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159782 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159783 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 1.7 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159784 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 1.9 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159785 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 2 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159786 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3.1 PDSP Ki 10.7270/Q2CR5RW8 7520908 Leysen, JE; Janssen, PM; Megens, AA; Schotte, A Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159810 CCCN(CCC)C1Cc2c[nH]c3ccc(C(C)=O)c(C1)c23 InChI=1S/C19H26N2O/c1-4-8-21(9-5-2)15-10-14-12-20-18-7-6-16(13(3)22)17(11-15)19(14)18/h6-7,12,15,20H,4-5,8-11H2,1-3H3 CKYZLYQSDNLGPT-UHFFFAOYSA-N 50094670 1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]indol-6-yl)-ethanone::CHEMBL276031::LY 293284::LY-293284::LY-293384 D(2) dopamine receptor Rattus norvegicus 1000 PDSP Ki 10.7270/Q2805146 7523657 Foreman, MM; Fuller, RW; Rasmussen, K; Nelson, DL; Calligaro, DO; Zhang, L; Barrett, JE; Booher, RN; Paget, CJ; Flaugh, ME Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094670&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18922713 103992546 CHEMBL276031 ZINC00005321 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161180 CN1CCc2cc(c(O)cc2C(C1)c1cccc2CCOc12)[N+]([O-])=O InChI=1S/C19H20N2O4/c1-20-7-5-13-9-17(21(23)24)18(22)10-15(13)16(11-20)14-4-2-3-12-6-8-25-19(12)14/h2-4,9-10,16,22H,5-8,11H2,1H3 XZPSYCOYKJRHKE-UHFFFAOYSA-N 81779 CAS_164252::NNC-687::NSC_164252 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/BF02245691 10.7270/Q29P3047 7855175 Karlsson, P; Farde, L; Halldin, C; Swahn, CG; Sedvall, G; Foged, C; Hansen, KT; Skrumsager, B Karolinska Institutet http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81779&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840885 131342353 ZINC31476325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161181 CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc2CCOc12 InChI=1S/C19H20ClNO2/c1-21-7-5-13-9-17(20)18(22)10-15(13)16(11-21)14-4-2-3-12-6-8-23-19(12)14/h2-4,9-10,16,22H,5-8,11H2,1H3 SKMVRXPBCSTNKE-UHFFFAOYSA-N 81778 CAS_132421::NNC-756::NSC_132421 D(2) dopamine receptor Rattus norvegicus 942 PDSP Ki 10.1007/BF02245691 10.7270/Q29P3047 7855175 Karlsson, P; Farde, L; Halldin, C; Swahn, CG; Sedvall, G; Foged, C; Hansen, KT; Skrumsager, B Karolinska Institutet http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14958952 131342352 ZINC03781602 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161182 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 895 PDSP Ki 10.1007/BF02245691 10.7270/Q29P3047 7855175 Karlsson, P; Farde, L; Halldin, C; Swahn, CG; Sedvall, G; Foged, C; Hansen, KT; Skrumsager, B Karolinska Institutet http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160225 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 46.5 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160226 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 18.3 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160227 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.9 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160228 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160229 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.3 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160230 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Rattus norvegicus 0.8 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160231 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160232 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Rattus norvegicus 0.4 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160233 Cc1cccc(N2CCN(CCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1C InChI=1S/C24H29N3O2/c1-18-5-3-6-23(19(18)2)27-14-12-26(13-15-27)11-4-16-29-21-9-7-20-8-10-24(28)25-22(20)17-21/h3,5-10,17H,4,11-16H2,1-2H3,(H,25,28) RRLWEQBPSAFVAS-UHFFFAOYSA-N 82065 CAS_163839::NSC_163839::OPC-4392 D(2) dopamine receptor Rattus norvegicus 19.8 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 163839 131342639 268 ZINC05116306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160234 Cc1cccc(N2CCN(CCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1C InChI=1S/C24H29N3O2/c1-18-5-3-6-23(19(18)2)27-14-12-26(13-15-27)11-4-16-29-21-9-7-20-8-10-24(28)25-22(20)17-21/h3,5-10,17H,4,11-16H2,1-2H3,(H,25,28) RRLWEQBPSAFVAS-UHFFFAOYSA-N 82065 CAS_163839::NSC_163839::OPC-4392 D(2) dopamine receptor Rattus norvegicus 18 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 163839 131342639 268 ZINC05116306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 160235 Cc1cccc(N2CCN(CCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1C InChI=1S/C24H29N3O2/c1-18-5-3-6-23(19(18)2)27-14-12-26(13-15-27)11-4-16-29-21-9-7-20-8-10-24(28)25-22(20)17-21/h3,5-10,17H,4,11-16H2,1-2H3,(H,25,28) RRLWEQBPSAFVAS-UHFFFAOYSA-N 82065 CAS_163839::NSC_163839::OPC-4392 D(2) dopamine receptor Rattus norvegicus 9.8 PDSP Ki 10.7270/Q29S1PJ5 7616416 Kikuchi, T; Tottori, K; Uwahodo, Y; Hirose, T; Miwa, T; Oshiro, Y; Morita, S Third Tokushima Institute of New Drug Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 163839 131342639 268 ZINC05116306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 162786 Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3 MOZPSIXKYJUTKI-UHFFFAOYSA-N 29525 3H-GR113808::CHEMBL518682::GR 113808::[3H] GR 113808::[3H]GR113808 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1111/j.1476-5381.1994.tb14064.x 10.7270/Q2BG2MHG 8012715 Gale, JD; Grossman, CJ; Whitehead, JW; Oxford, AW; Bunce, KT; Humphrey, PP Glaxo Group Research Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 119376 81054954 73380 CHEMBL518682 259 ZINC00598220 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161700 CCNC(=O)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 InChI=1S/C23H29F2N3O/c1-2-26-23(29)28-16-14-27(15-17-28)13-3-4-22(18-5-9-20(24)10-6-18)19-7-11-21(25)12-8-19/h5-12,22H,2-4,13-17H2,1H3,(H,26,29) NNAIYOXJNVGUOM-UHFFFAOYSA-N 50311786 Amperozide::CHEMBL1079935 D(2) dopamine receptor Rattus norvegicus 501.18 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50311786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50311786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73333 104146147 CHEMBL1079935 DB08927 ZINC04214849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161701 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 1.25 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161702 CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3 XRYLGRGAWQSVQW-UHFFFAOYSA-N 22872 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methyl-piperazine;maleate::1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine::1-{6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine::CHEMBL64249::CLOROTEPINE (+)::CLOROTEPINE(-)::Clothepin::OCTOCLOTHEPIN,(+)::OCTOCLOTHEPIN,(-)::Octoclothepin::Octoclothepine D(2) dopamine receptor Rattus norvegicus 1.58 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1238 49846686 CHEMBL64249 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161703 CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3 XRYLGRGAWQSVQW-UHFFFAOYSA-N 22872 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methyl-piperazine;maleate::1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine::1-{6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine::CHEMBL64249::CLOROTEPINE (+)::CLOROTEPINE(-)::Clothepin::OCTOCLOTHEPIN,(+)::OCTOCLOTHEPIN,(-)::Octoclothepin::Octoclothepine D(2) dopamine receptor Rattus norvegicus 12.58 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1238 49846686 CHEMBL64249 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161704 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 56.23 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161705 CN1CCN(CC1)C1=Nc2cc(F)ccc2Cc2ccccc12 InChI=1S/C19H20FN3/c1-22-8-10-23(11-9-22)19-17-5-3-2-4-14(17)12-15-6-7-16(20)13-18(15)21-19/h2-7,13H,8-12H2,1H3 OBWGMKKHCLHVIE-UHFFFAOYSA-N 50040241 3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine(fluperlapine)::CHEMBL63756::Fluperlapine D(2) dopamine receptor Rattus norvegicus 316.22 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 49381 103972301 CHEMBL63756 279 C10967 ZINC26247473 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161706 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Rattus norvegicus 0.5 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161707 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.5 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161708 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Rattus norvegicus 7.94 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161709 CC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3 DKMFBWQBDIGMHM-UHFFFAOYSA-N 81771 CAS_3575-80-2::MELPERONE::NSC_15387 D(2) dopamine receptor Rattus norvegicus 199.52 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15387 131342345 DB09224 ZINC00001672 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161710 CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O InChI=1S/C21H26N2OS2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(26(2)24)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 SLVMESMUVMCQIY-UHFFFAOYSA-N 50131440 10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine::2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine::CHEMBL1088::MESORIDAZINE::NC-123::Serentil::TPS-23 D(2) dopamine receptor Rattus norvegicus 7.94 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4078 104022598 6780 CHEMBL1088 DB00933 7227 C07143 ZINC03831042 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161711 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Rattus norvegicus 15.84 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161712 CN1CCN(CC1)C1=Nc2ccccc2Cc2ccccc12 InChI=1S/C19H21N3/c1-21-10-12-22(13-11-21)19-17-8-4-2-6-15(17)14-16-7-3-5-9-18(16)20-19/h2-9H,10-14H2,1H3 PWRPUAKXMQAFCJ-UHFFFAOYSA-N 50102325 6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::CHEMBL340801::Perlapine D(2) dopamine receptor Rattus norvegicus 501.18 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16106 103998865 CHEMBL340801 ZINC27303430 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161713 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 RGCVKNLCSQQDEP-UHFFFAOYSA-N 50130273 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine D(2) dopamine receptor Rattus norvegicus 0.63 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4748 104021707 8028 CHEMBL567 DB00850 209 C07427 ZINC19228902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161714 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Rattus norvegicus 2.51 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161715 CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C20H24ClN3S/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24/h2-3,5-8,15H,4,9-14H2,1H3 WIKYUJGCLQQFNW-UHFFFAOYSA-N 78434 2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid::2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid::Compazine::Compro::MLS001148133::PROCHLORPERAZINE::SMR000653454::cid_91499 D(2) dopamine receptor Rattus norvegicus 5.01 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search P77 3M0W 4917 252655190 8435 DB00433 C07403 ZINC19796018 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161716 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.99 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161717 CN1CCN(CC1)C1=Cc2cc(Cl)ccc2C(=CC#N)c2ccccc12 InChI=1S/C22H20ClN3/c1-25-10-12-26(13-11-25)22-15-16-14-17(23)6-7-18(16)20(8-9-24)19-4-2-3-5-21(19)22/h2-8,14-15H,10-13H2,1H3 UJCYUJOQBXHJFH-UHFFFAOYSA-N 81769 CAS_79781-95-6::NSC_3052780::RILAPINE D(2) dopamine receptor Rattus norvegicus 39.81 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81769&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6446980 131342343 ZINC14953573 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161718 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 1.58 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161719 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.06 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161720 CN1CCN(CC1)C1=Nc2cscc2C(=CC#N)c2cscc12 InChI=1S/C17H16N4S2/c1-20-4-6-21(7-5-20)17-15-10-22-8-13(15)12(2-3-18)14-9-23-11-16(14)19-17/h2,8-11H,4-7H2,1H3 RVQVUMIXBGFJLZ-UHFFFAOYSA-N 81770 CAS_82650-83-7::NSC_3086153::TENILAPINE D(2) dopamine receptor Rattus norvegicus 1584.89 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81770&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6510284 131342344 ZINC60027294 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161721 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 7.94 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161722 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1 InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8- GFBKORZTTCHDGY-UWVJOHFNSA-N 78576 CIS-THIOTHIXENE::MLS000028463::SMR000058396::THIOTHIXENE::cid_941651::med.21724, Compound Thiothixene D(2) dopamine receptor Rattus norvegicus 0.63 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941651 252655323 DB01623 212 ZINC30690433 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161723 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2 ZFZPJDFBJFHYIV-UHFFFAOYSA-N 50007692 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL1204189::CHEMBL35057::TIOSPERONE D(2) dopamine receptor Rattus norvegicus 0.5 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55752 103920962 CHEMBL1204189CHEMBL35057 101 ZINC01915508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161724 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Rattus norvegicus 0.19 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161725 CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3 HDOZVRUNCMBHFH-UHFFFAOYSA-N 35255 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine D(2) dopamine receptor Rattus norvegicus 1 PDSP Ki 10.7270/Q2154FJQ 7908055 Roth, BL; Craigo, SC; Choudhary, MS; Uluer, A; Monsma, FJ; Shen, Y; Meltzer, HY; Sibley, DR Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ZOT 6A94 5736 85753334 32316 CHEMBL285802 DB09225 103 ZINC00002264 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 161752 Cc1cccc(NC(=O)N[C@@H]2N=C(c3ccccc3)c3ccccc3N(CC(=O)c3ccccc3C)C2=O)c1 InChI=1S/C32H28N4O3/c1-21-11-10-15-24(19-21)33-32(39)35-30-31(38)36(20-28(37)25-16-7-6-12-22(25)2)27-18-9-8-17-26(27)29(34-30)23-13-4-3-5-14-23/h3-19,30H,20H2,1-2H3,(H2,33,35,39)/t30-/m0/s1 YCXFHPUBGMMWJQ-PMERELPUSA-N 50056101 1-[(R)-2-Oxo-1-(2-oxo-2-o-tolyl-ethyl)-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-m-tolyl-urea::CHEMBL115121::YM022::YM022 Racemate D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.7270/Q2WD3Z2F 7910212 Nishida, A; Miyata, K; Tsutsumi, R; Yuki, H; Akuzawa, S; Kobayashi, A; Kamato, T; Ito, H; Yamano, M; Katuyama, Y Yamanouchi Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056101&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122130 103952505 CHEMBL115121 888 ZINC03786250 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 162970 CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCCCCCc2n1 InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3 XVGOZDAJGBALKS-UHFFFAOYSA-N 50160807 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,6,7,8,9,10-hexahydro-cycloocta[b]pyridine::AD-5423::Blonanserin::CHEMBL178803 D(2) dopamine receptor Rattus norvegicus 14.8 PDSP Ki 10.7270/Q2TH8K60 8093723 Oka, M; Noda, Y; Ochi, Y; Furukawa, K; Une, T; Kurumiya, S; Hino, K; Karasawa, T Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 125564 104047267 CHEMBL178803 DB09223 ZINC00597434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 162971 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 8.66 PDSP Ki 10.7270/Q2TH8K60 8093723 Oka, M; Noda, Y; Ochi, Y; Furukawa, K; Une, T; Kurumiya, S; Hino, K; Karasawa, T Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 162972 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 149 PDSP Ki 10.7270/Q2TH8K60 8093723 Oka, M; Noda, Y; Ochi, Y; Furukawa, K; Une, T; Kurumiya, S; Hino, K; Karasawa, T Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 162973 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 8.79 PDSP Ki 10.7270/Q2TH8K60 8093723 Oka, M; Noda, Y; Ochi, Y; Furukawa, K; Une, T; Kurumiya, S; Hino, K; Karasawa, T Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159510 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT D(2) dopamine receptor Rattus norvegicus 1655 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159511 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 540 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159512 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 1.8 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159513 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159514 OCCC1CCN(CCC=C2c3ccc(F)cc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C24H25F4NOS/c25-18-4-5-20-19(2-1-10-29-11-7-16(8-12-29)9-13-30)21-14-17(24(26,27)28)3-6-22(21)31-23(20)15-18/h2-6,14-16,30H,1,7-13H2 CCUOZZURYIZOKX-UHFFFAOYSA-N 81490 CAS_60197-32-2::CIS PIFLUTIXOL::NSC_68714::Piflutixol::cis piflutixol-(Z) D(2) dopamine receptor Rattus norvegicus 1 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81490&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5477380 131342064 ZINC01570576 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159515 CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 InChI=1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3 AAOVKJBEBIDNHE-UHFFFAOYSA-N 50000766 CHEMBL12::DIAZEPAM::US9271961, Diazepam D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search DZP 6HUP,2BXF,6X3X 3016 103915310 49575 CHEMBL12 DB00829 3364 C06948 ZINC00006427 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159516 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 2627 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159517 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Rattus norvegicus 0.8 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159518 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Rattus norvegicus 94 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159519 NCCCC(O)=O InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7) BTCSSZJGUNDROE-UHFFFAOYSA-N 24183 4-amino-n-[2,3-3H]butyric acid::4-aminobutanoic acid::Aminalon::CHEMBL96::GABA::Gamma-Aminobutyric acid::[3H]GABA::cid_119 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ABU 5LTV,2YOE,1M19,6SSI,1QUR,7OPM,6JDW,4M3C,4ATQ,6PLO,6PLV,4MS3,4EUO,7QNB,7QNA,6D6U,7K2O,1M1A,3IP9,6EB3,4K17,7PBZ,6HUO,6HUP,7PBD,6A96,8DD2,8DD3,4RLG,6D6T,7Y7W,6DW1,6DW0,1S32,6X3W,6X3V,6X3U,6X3T,6X3Z,6X3X,5T4J,2JT9,4PCR,2OKJ,2OKK,7QN7,3V5A,6HUJ,5OE1,6DN6,5LRV,3USU,7T0Z,6PLZ,6PLX,6PLY,6PLP,6PLQ,6PLW,6PLU,5ODM,6X40,5X03,7X4Y,4I30 119 53786180 16865 CHEMBL96 DB02530 1067 C00334 ZINC01532620 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159520 N[C@@H](CCC(O)=O)C(O)=O InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1 WHUUTDBJXJRKMK-VKHMYHEASA-N 17657 (2S)-2-aminopentanedioic acid::(S)-Glu::D-Glutamate::Glutamate::L-Glu::L-Glutamate::L-Glutamic acid::L-[14C(U)]glutamate::L-gluatmate D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17657&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GGL 5BPU,2DBW,7F5X,7WXX,1BX9,1AXD,1GUL,7WJ4,8AO0,3THS,1FAV,7FIN,7ULF,5ONJ,2M5P,2M5Q 33032 46517819 18237 DB00142 1369 C00302 ZINC01482113 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159521 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.8 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159522 NCCc1cnc[nH]1 InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8) NTYJJOPFIAHURM-UHFFFAOYSA-N 7966 2-(1H-imidazol-4-yl)ethan-1-amine::CHEMBL544208::CHEMBL90::Ceplene::Ergotidine::HISTAMINE DIHYDROCHLORIDE::Histamine::L-histamine::Peremin::[3H]histamine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1AVN,1IKE,1JQD,1KAR,1NP1,1QFT,1QFV,1U18 774 11108702 18295 CHEMBL90CHEMBL544208 DB00667 1247 ZINC18217584 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159523 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 397 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159524 CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3cn(C)c4cccc(C2=C1)c34 InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15+,19-/m1/s1 KPJZHOPZRAFDTN-ZRGWGRIASA-N 50031942 (6aR,9R)-4,6a,7-Trimethyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (1-hydroxymethyl-propyl)-amide::(6aR,9R)-4,7-Dimethyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid ((S)-1-hydroxymethyl-propyl)-amide::(6aR,9R)-4-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (1-hydroxymethyl-propyl)-amide::(6aR,9R)-5,7-Dimethyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid diethylamide::(methylsergide)4,7-Dimethyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (1-hydroxymethyl-propyl)-amide::4,7-Dimethyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (1-hydroxymethyl-propyl)-amide::CHEMBL1065::METHYSERGIDE::Sansert D(2) dopamine receptor Rattus norvegicus 116 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search H8J 6DRZ 9681 103940495 584020 CHEMBL1065 134 C07199 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159525 NCC(O)c1ccc(O)c(O)c1 InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2 SFLSHLFXELFNJZ-UHFFFAOYSA-N 35234 DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LNR 3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH 951 85753313 33569 484 ZINC00057624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159526 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2 RGCVKNLCSQQDEP-UHFFFAOYSA-N 50130273 2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol::2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine::2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol::4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol::4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperazineethanol::CHEMBL567::Chlorpiprazine::PERPHENAZINE::Perfenazine::Perphenazin::Trilafon::gamma-(4-(beta-hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine D(2) dopamine receptor Rattus norvegicus 1.3 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4748 104021707 8028 CHEMBL567 DB00850 209 C07427 ZINC19228902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159527 CN1CCc2cc(Cl)c(O)cc2[C@@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m0/s1 GOTMKOSCLKVOGG-HNNXBMFYSA-N 82248 CAS_73445-63-3::SCH 23388 (S-enantiomer) D(2) dopamine receptor Rattus norvegicus 988 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82248&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603800 136350220 ZINC02017840 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159528 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 760 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159529 CN1C2CC(CC1C1OC21)OC(=O)C(CO)c1ccccc1 InChI=1S/C17H21NO4/c1-18-13-7-11(8-14(18)16-15(13)22-16)21-17(20)12(9-19)10-5-3-2-4-6-10/h2-6,11-16,19H,7-9H2,1H3 STECJAGHUSJQJN-UHFFFAOYSA-N 50015720 (hyoscine)3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9-aza-tricyclo[3.3.1.0*2,4*]non-7-yl ester::3-hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9-aza-tricyclo[3.3.1.0*2,4*]non-7-yl ester::9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl 3-hydroxy-2-phenylpropanoate::Benzotropine3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9-aza-tricyclo[3.3.1.0*2,4*]non-7-yl ester::CHEMBL13030::ChEMBL_11434::SCOPOLAMINE D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50015720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50015720&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5184 103927410 CHEMBL13030 330 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159530 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.12 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159531 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 1102 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159532 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 10 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159533 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 9.1 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159534 OCCC1CCN(CC\C=C2/c3ccc(F)cc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C24H25F4NOS/c25-18-4-5-20-19(2-1-10-29-11-7-16(8-12-29)9-13-30)21-14-17(24(26,27)28)3-6-22(21)31-23(20)15-18/h2-6,14-16,30H,1,7-13H2/b19-2+ CCUOZZURYIZOKX-FQJNFEMKSA-N 82246 trans piflutixol-(E) D(2) dopamine receptor Rattus norvegicus 73 PDSP Ki 10.1016/0024-3205(84)90540-x 10.7270/Q2JD4V9M 6387355 Billard, W; Ruperto, V; Crosby, G; Iorio, LC; Barnett, A Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82246&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5477380 136350218 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159562 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 680 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159564 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 3.1 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159566 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 2.3 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159568 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.72 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159570 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.61 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159572 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 310 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159574 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 210 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159576 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/p-1/t3-,5-,6-,9-/m1/s1 XKMLYUALXHKNFT-UUOKFMHZSA-M 81874 Dopamine+ (GTP+)::Dopamine+GTP::NPA+ (GTP+) D(2) dopamine receptor Rattus norvegicus 1300 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91898390 131342448 15996 C03517 ZINC60094177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159577 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]1O InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/p-1/t3-,5-,6-,9-/m1/s1 XKMLYUALXHKNFT-UUOKFMHZSA-M 81874 Dopamine+ (GTP+)::Dopamine+GTP::NPA+ (GTP+) D(2) dopamine receptor Rattus norvegicus 2900 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91898390 131342448 15996 C03517 ZINC60094177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159578 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Rattus norvegicus 1.8 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159580 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Rattus norvegicus 0.76 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159582 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Rattus norvegicus 220 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159584 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Rattus norvegicus 65 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159586 CCCN(CCC)CCc1ccc(O)c(O)c1 InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3 LMYSNFBROWBKMB-UHFFFAOYSA-N 50019396 4-(2-Dipropylamino-ethyl)-benzene-1,2-diol::4-(2-Dipropylamino-ethyl)-benzene-1,2-diol (N,N-dipropyldopamine)::CHEMBL15564::N,N-di-n-Propyldopamine D(2) dopamine receptor Rattus norvegicus 130 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019396&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3106 103930360 CHEMBL15564 ZINC02539818 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159588 CCCN(CCC)CCc1ccc(O)c(O)c1 InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3 LMYSNFBROWBKMB-UHFFFAOYSA-N 50019396 4-(2-Dipropylamino-ethyl)-benzene-1,2-diol::4-(2-Dipropylamino-ethyl)-benzene-1,2-diol (N,N-dipropyldopamine)::CHEMBL15564::N,N-di-n-Propyldopamine D(2) dopamine receptor Rattus norvegicus 130 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019396&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3106 103930360 CHEMBL15564 ZINC02539818 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159590 Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19) MRBDMNSDAVCSSF-UHFFFAOYSA-N 31046 3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430 D(2) dopamine receptor Rattus norvegicus 1500 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5775 252615298 DB00692 ZINC00020251 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159591 Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19) MRBDMNSDAVCSSF-UHFFFAOYSA-N 31046 3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430 D(2) dopamine receptor Rattus norvegicus 750 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5775 252615298 DB00692 ZINC00020251 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159593 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 720 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159594 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 580 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159596 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.08 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159598 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.08 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159599 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 180 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159601 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 320 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159603 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 7.9 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 159605 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 16 PDSP Ki 10.7270/Q2902291 6655559 Zahniser, NR; Dubocovich, ML University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 172290 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 125 PDSP Ki 10.1016/0893-133X(94)00129-N 10.7270/Q2445K1M 8822531 Bymaster, FP; Calligaro, DO; Falcone, JF; Marsh, RD; Moore, NA; Tye, NC; Seeman, P; Wong, DT Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 172291 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1 PDSP Ki 10.1016/0893-133X(94)00129-N 10.7270/Q2445K1M 8822531 Bymaster, FP; Calligaro, DO; Falcone, JF; Marsh, RD; Moore, NA; Tye, NC; Seeman, P; Wong, DT Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 172293 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Rattus norvegicus 11 PDSP Ki 10.1016/0893-133X(94)00129-N 10.7270/Q2445K1M 8822531 Bymaster, FP; Calligaro, DO; Falcone, JF; Marsh, RD; Moore, NA; Tye, NC; Seeman, P; Wong, DT Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 172294 CN1CC2C(C1)c1cc(Cl)ccc1Oc1ccccc21 InChI=1S/C17H16ClNO/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19/h2-8,14-15H,9-10H2,1H3 VSWBSWWIRNCQIJ-UHFFFAOYSA-N 84994 CAS_163091::NSC_163091::ORG-5222 D(2) dopamine receptor Rattus norvegicus 1 PDSP Ki 10.1016/0893-133X(94)00129-N 10.7270/Q2445K1M 8822531 Bymaster, FP; Calligaro, DO; Falcone, JF; Marsh, RD; Moore, NA; Tye, NC; Seeman, P; Wong, DT Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903970 136351094 71255 DB06216 ZINC11677376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 172295 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Rattus norvegicus 160 PDSP Ki 10.1016/0893-133X(94)00129-N 10.7270/Q2445K1M 8822531 Bymaster, FP; Calligaro, DO; Falcone, JF; Marsh, RD; Moore, NA; Tye, NC; Seeman, P; Wong, DT Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 172296 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Rattus norvegicus 275 PDSP Ki 10.1016/0893-133X(94)00129-N 10.7270/Q2445K1M 8822531 Bymaster, FP; Calligaro, DO; Falcone, JF; Marsh, RD; Moore, NA; Tye, NC; Seeman, P; Wong, DT Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 172297 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3 PDSP Ki 10.1016/0893-133X(94)00129-N 10.7270/Q2445K1M 8822531 Bymaster, FP; Calligaro, DO; Falcone, JF; Marsh, RD; Moore, NA; Tye, NC; Seeman, P; Wong, DT Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171142 Cc1nc[nH]c1CC1CCc2c(C)c3ccccc3n2C1=O InChI=1S/C18H19N3O/c1-11-14-5-3-4-6-17(14)21-16(11)8-7-13(18(21)22)9-15-12(2)19-10-20-15/h3-6,10,13H,7-9H2,1-2H3,(H,19,20) AEKQMJRJRAHOAP-UHFFFAOYSA-N 84928 CAS_125368::FK 1052::NSC_125368 D(2) dopamine receptor Rattus norvegicus 0.01 PDSP Ki 10.7270/Q2CV4G73 8496821 Nagakura, Y; Kadowaki, M; Tokoro, K; Tomoi, M; Mori, J; Kohsaka, M Fujisawa Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84928&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 125368 136351028 ZINC11616570 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170119 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 2.6 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170120 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 142.5 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170121 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 170 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170122 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.06 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170123 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.02 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170124 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)NP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H17N6O13P3/c11-10-13-7-4(8(19)14-10)12-2-16(7)9-6(18)5(17)3(28-9)1-27-32(25,26)29-31(23,24)15-30(20,21)22/h2-3,5-6,9,17-18H,1H2,(H,25,26)(H3,11,13,14,19)(H4,15,20,21,22,23,24)/t3-,5-,6-,9-/m1/s1 UQABYHGXWYXDTK-UUOKFMHZSA-N 81791 Dopamine + GPP(NH)p::GPP(NH)P(+)::GPP(NH)p(-)::Guanylyl imidodiphosphate D(2) dopamine receptor Rattus norvegicus 2380 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 36735 131342365 C02058 ZINC37868676 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170125 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 15.5 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171293 Clc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1 InChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2 QWGDMFLQWFTERH-UHFFFAOYSA-N 22870 13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-piperazin-1-yldibenzo[b,f][1,4]oxazepine::Amoxapine::Asendin::CHEMBL1113::Demolox D(2) dopamine receptor Rattus norvegicus 20 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2170 49846684 2675 CHEMBL1113 DB00543 201 ZINC00000931 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171294 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171295 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)c(c1)C(F)(F)F InChI=1S/C22H22ClF4NO2/c23-19-8-5-16(14-18(19)22(25,26)27)21(30)9-12-28(13-10-21)11-1-2-20(29)15-3-6-17(24)7-4-15/h3-8,14,30H,1-2,9-13H2 LZFSKNPPWIFMFL-UHFFFAOYSA-N 81487 CAS_10457-91-7::CLOFLUPEROL::NSC_25293 D(2) dopamine receptor Rattus norvegicus 56 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81487&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25293 131342061 ZINC00538335 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171296 Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)C(=O)NC1CCCCC1 InChI=1S/C21H30FN3O2/c22-18-10-8-17(9-11-18)20(26)7-4-12-24-13-15-25(16-14-24)21(27)23-19-5-2-1-3-6-19/h8-11,19H,1-7,12-16H2,(H,23,27) LVCCSKJMBMJXHF-UHFFFAOYSA-N 84947 CAS_128995::FG 5803::NSC_128995 D(2) dopamine receptor Rattus norvegicus 501 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128996 136351047 ZINC60027295 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171297 CN1CCN(CC1)C1=Nc2cc(F)ccc2Cc2ccccc12 InChI=1S/C19H20FN3/c1-22-8-10-23(11-9-22)19-17-5-3-2-4-14(17)12-15-6-7-16(20)13-18(15)21-19/h2-7,13H,8-12H2,1H3 OBWGMKKHCLHVIE-UHFFFAOYSA-N 50040241 3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine(fluperlapine)::CHEMBL63756::Fluperlapine D(2) dopamine receptor Rattus norvegicus 316 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 49381 103972301 CHEMBL63756 279 C10967 ZINC26247473 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171298 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Rattus norvegicus 0.5 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171299 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.5 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171300 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Rattus norvegicus 8 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171301 CC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C16H22FNO/c1-13-8-11-18(12-9-13)10-2-3-16(19)14-4-6-15(17)7-5-14/h4-7,13H,2-3,8-12H2,1H3 DKMFBWQBDIGMHM-UHFFFAOYSA-N 81771 CAS_3575-80-2::MELPERONE::NSC_15387 D(2) dopamine receptor Rattus norvegicus 199 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15387 131342345 DB09224 ZINC00001672 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171302 CN1CCCCC1CCN1c2ccccc2Sc2ccc(cc12)S(C)=O InChI=1S/C21H26N2OS2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(26(2)24)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 SLVMESMUVMCQIY-UHFFFAOYSA-N 50131440 10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylsulfinyl)-10H-phenothiazine::2-Methanesulfinyl-10-[2-(1-methyl-piperidin-2-yl)-ethyl]-10H-phenothiazine::CHEMBL1088::MESORIDAZINE::NC-123::Serentil::TPS-23 D(2) dopamine receptor Rattus norvegicus 5 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4078 104022598 6780 CHEMBL1088 DB00933 7227 C07143 ZINC03831042 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171303 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Rattus norvegicus 45 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171304 CN1CCN(CC1)C1=Nc2ccccc2Cc2ccccc12 InChI=1S/C19H21N3/c1-21-10-12-22(13-11-21)19-17-8-4-2-6-15(17)14-16-7-3-5-9-18(16)20-19/h2-9H,10-14H2,1H3 PWRPUAKXMQAFCJ-UHFFFAOYSA-N 50102325 6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::CHEMBL340801::Perlapine D(2) dopamine receptor Rattus norvegicus 501 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16106 103998865 CHEMBL340801 ZINC27303430 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171305 Fc1ccc(cc1)C(CCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc(F)cc1 InChI=1S/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34) YVUQSNJEYSNKRX-UHFFFAOYSA-N 50334150 1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one::1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one(Pimozide)::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::1-{1-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Pimozide)::CHEMBL1423::MCN-JR-6238::N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)benzenamine::NCGC00015802::Orap::PIMOZIDE1-{1-[4,4-BIS-(4-FLUORO-PHENYL)-BUTYL]-PIPERIDIN-4-YL}-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE::Pimozide::R-6238 D(2) dopamine receptor Rattus norvegicus 2.5 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50334150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50334150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1II 7WLL 16362 125084252 8212 CHEMBL1423 DB01100 90 C07566 ZINC19796084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171306 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Rattus norvegicus 329 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171307 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 1.5 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171308 CN(C)CCC=C1c2ccccc2C=Nc2ccc(Cl)cc12 InChI=1S/C19H19ClN2/c1-22(2)11-5-8-17-16-7-4-3-6-14(16)13-21-19-10-9-15(20)12-18(17)19/h3-4,6-10,12-13H,5,11H2,1-2H3 KGRYJYZBJQLPFW-UHFFFAOYSA-N 84946 CAS_170154::NSC_170154::RMI 81,582 D(2) dopamine receptor Rattus norvegicus 79 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5834968 136351046 ZINC05573060 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171309 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.06 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171310 CN1CCN(CC1)C1=Nc2cscc2C(=CC#N)c2cscc12 InChI=1S/C17H16N4S2/c1-20-4-6-21(7-5-20)17-15-10-22-8-13(15)12(2-3-18)14-9-23-11-16(14)19-17/h2,8-11H,4-7H2,1H3 RVQVUMIXBGFJLZ-UHFFFAOYSA-N 81770 CAS_82650-83-7::NSC_3086153::TENILAPINE D(2) dopamine receptor Rattus norvegicus 1584 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81770&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6510284 131342344 ZINC60027294 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171311 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 7.9 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171312 CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1 InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8- GFBKORZTTCHDGY-UWVJOHFNSA-N 78576 CIS-THIOTHIXENE::MLS000028463::SMR000058396::THIOTHIXENE::cid_941651::med.21724, Compound Thiothixene D(2) dopamine receptor Rattus norvegicus 0.63 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941651 252655323 DB01623 212 ZINC30690433 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171313 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2 ZFZPJDFBJFHYIV-UHFFFAOYSA-N 50007692 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL1204189::CHEMBL35057::TIOSPERONE D(2) dopamine receptor Rattus norvegicus 0.5 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55752 103920962 CHEMBL1204189CHEMBL35057 101 ZINC01915508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171314 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Rattus norvegicus 0.2 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171315 CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3 HDOZVRUNCMBHFH-UHFFFAOYSA-N 35255 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine D(2) dopamine receptor Rattus norvegicus 1 PDSP Ki 10.1007/bf02311185 10.7270/Q2VT1QKB 8524985 Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ZOT 6A94 5736 85753334 32316 CHEMBL285802 DB09225 103 ZINC00002264 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170126 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 7700 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170127 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.37 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170128 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.28 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170129 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 71.6 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170130 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 57 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170131 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Rattus norvegicus 0.02 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 170132 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Rattus norvegicus 0.03 PDSP Ki 10.7270/Q2S75DWP 8301592 Tang, L; Todd, RD; Heller, A; O'Malley, KL Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171378 Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17+/m1/s1 BGOQGUHWXBGXJW-PBHICJAKSA-N 50010685 (+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine::(6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL43345::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 43.2 PDSP Ki 10.1021/jm950707+ 10.7270/Q2736PF6 8558526 Ghosh, D; Snyder, SE; Watts, VJ; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010685&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14708665 103923431 CHEMBL43345 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171379 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 0.92 PDSP Ki 10.1021/jm950707+ 10.7270/Q2736PF6 8558526 Ghosh, D; Snyder, SE; Watts, VJ; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171380 Oc1ccc2[C@@H]3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2/t13-/m0/s1 ZQTSNGJHMUKLOM-ZDUSSCGKSA-N 50117181 (S)-2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL124561::Dinapsoline, (+/-)::Dinapsoline, (R)(+) D(2) dopamine receptor Rattus norvegicus 31.3 PDSP Ki 10.1021/jm950707+ 10.7270/Q2736PF6 8558526 Ghosh, D; Snyder, SE; Watts, VJ; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816455 104010781 CHEMBL124561 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171457 NC(SCCCc1cnc[nH]1)=NCCc1ccc(I)cc1 InChI=1S/C15H19IN4S/c16-13-5-3-12(4-6-13)7-8-19-15(17)21-9-1-2-14-10-18-11-20-14/h3-6,10-11H,1-2,7-9H2,(H2,17,19)(H,18,20) UBHYDQAARZKHEZ-UHFFFAOYSA-N 22913 CHEMBL1237146::CHEMBL498770::Iodophenpropit::{[3-(1H-imidazol-5-yl)propyl]sulfanyl}-N''-[2-(4-iodophenyl)ethyl]methanimidamide D(2) dopamine receptor Rattus norvegicus 4500 PDSP Ki 10.1111/j.1476-5381.1995.tb15071.x 10.7270/Q2ZK5F64 8564266 Leurs, R; Tulp, MT; Menge, WM; Adolfs, MJ; Zuiderveld, OP; Timmerman, H Vrije Universiteit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22913&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3035746 49846727 CHEMBL498770CHEMBL1237146 ZINC14979644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171458 NC(SCCCc1cnc[nH]1)=NCCc1ccc(I)cc1 InChI=1S/C15H19IN4S/c16-13-5-3-12(4-6-13)7-8-19-15(17)21-9-1-2-14-10-18-11-20-14/h3-6,10-11H,1-2,7-9H2,(H2,17,19)(H,18,20) UBHYDQAARZKHEZ-UHFFFAOYSA-N 22913 CHEMBL1237146::CHEMBL498770::Iodophenpropit::{[3-(1H-imidazol-5-yl)propyl]sulfanyl}-N''-[2-(4-iodophenyl)ethyl]methanimidamide D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1111/j.1476-5381.1995.tb15071.x 10.7270/Q2ZK5F64 8564266 Leurs, R; Tulp, MT; Menge, WM; Adolfs, MJ; Zuiderveld, OP; Timmerman, H Vrije Universiteit http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22913&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3035746 49846727 CHEMBL498770CHEMBL1237146 ZINC14979644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 171609 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.2 PDSP Ki 10.1007/bf00168557 10.7270/Q2Q52N48 8584042 Borsini, F; Giraldo, E; Monferini, E; Antonini, G; Parenti, M; Bietti, G; Donetti, A Boehringer Ingelheim Italia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 172120 CC(N)Cc1c[nH]c2ccc(OCc3cccs3)cc12 InChI=1S/C16H18N2OS/c1-11(17)7-12-9-18-16-5-4-13(8-15(12)16)19-10-14-3-2-6-20-14/h2-6,8-9,11,18H,7,10,17H2,1H3 ALFGDCNSEBJYSP-UHFFFAOYSA-N 82472 BW-723C86::CAS_5311036::NSC_5311036 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/0166-4328(96)00087-3 10.7270/Q2RX99ND 8788493 Baxter, GS SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4284720 136350443 ZINC03995822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173538 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 790 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173539 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 13 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173540 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 XMXHEBAFVSFQEX-UHFFFAOYSA-N 50034043 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE D(2) dopamine receptor Rattus norvegicus 54 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71360 103942259 65173 CHEMBL14376 DB04946 87 ZINC01548097 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173541 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Rattus norvegicus 52.3 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173542 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Rattus norvegicus 329 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173543 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 20 PDSP Ki 10.1016/s0014-2999(96)00840-0 10.7270/Q2DF6PR7 8997630 Kongsamut, S; Roehr, JE; Cai, J; Hartman, HB; Weissensee, P; Kerman, LL; Tang, L; Sandrasagra, A Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173671 NCCc1c[nH]c2ccc(O)cc12 InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 QZAYGJVTTNCVMB-UHFFFAOYSA-N 10755 14C-5-hydroxy tryptamine creatinine disulfate::2-imino-1-methylimidazolidin-4-one; 3-(2-aminoethyl)-1H-indol-5-ol; bis(sulfuric acid)::5-HT::5-Hydroxy Tryptamine::5-hydroxy tryptamine creatinine disulfate::CHEMBL535832::Serotonin::[3H]-5-HT D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=10755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=10755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SRO 7WB7,7CFP,7BS9,3Q6K,3ADV,7YS6,6DG8,6DG7,7E2Y,7CFQ,2YMD,5MT3,5MT9,7TX8,7LI9,7LIA,6Y5A,7WC4,5MAM,6HIO,6HIN,6HIQ,7E32,3NK1,6KHN,2QEH,7BS2,3BRN,7MGW,4DUF,4DUE,7DAL,4DTW,7XTA,7XTB,7XT9,7XT8 5202 172097186 28790 CHEMBL535832 C00780 ZINC00057058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173672 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 1110 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173673 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 1400 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173675 [NH3+][C@@H]1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2/p+1/t8-/m1/s1 ASXGAOFCKGHGMF-MRVPVSSYSA-O 50091032 6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl-ammonium(R(+)ADTN)::Aminotetralin-6,7-dihydroxy-(+) D(2) dopamine receptor Rattus norvegicus 59 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332855 103989453 ZINC03872369 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173676 N[C@H]1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2/t8-/m0/s1 ASXGAOFCKGHGMF-QMMMGPOBSA-N 85046 Aminotetralin-6,7-dihydroxy-(-) D(2) dopamine receptor Rattus norvegicus 930 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23760136 136351146 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173678 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 1270 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173680 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 68 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173681 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 1210 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173683 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 210 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173684 Clc1cccc(Cl)c1N=C1NCCN1 InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14) GJSURZIOUXUGAL-UHFFFAOYSA-N 50016897 2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2)::2-(2,6-dichloroanilino)-2-imidazoline::CLONIDINE::N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine::clonidine (amino form) D(2) dopamine receptor Rattus norvegicus 1980 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016897&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search CLU 2PNC,7AWW 2803 103928231 46632 516 ZINC00896484 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173686 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 420 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173688 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 192 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173689 CNCC(O)c1ccc(O)c(O)c1 InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3 UCTWMZQNUQWSLP-UHFFFAOYSA-N 84342 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol::4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, 1::4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride::4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol;hydrochloride::4-[2-(methylamino)-1-oxidanyl-ethyl]benzene-1,2-diol;hydrochloride::DL-ADRENALINE HYDROCHLORIDE::EPINEPHRINE::EPINEPHRINE,(+)::MLS001333244::SMR000058236::cid_5924 D(2) dopamine receptor Rattus norvegicus 427 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ALE 7BTS,4A7U,7BRN,2HKK,4LDO 838 252659436 C02012 ZINC00039090 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173690 OCCN1CCN(CC\C=C2/c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5+ NJMYODHXAKYRHW-BLLMUTORSA-N 50026957 (cis) 2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol(Flupentixol)::(trans-flupenthixol)2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::2-(4-{3-[2-Trifluoromethyl-thioxanthen-(9E)-ylidene]-propyl}-piperazin-1-yl)-ethanol::2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::FLUPENTHIXOL, Alpha::FLUPENTHIXOL2-{4-[3-(2-Trifluoromethyl-thioxanthen-9-ylidene)-propyl]-piperazin-1-yl}-ethanol::Flupenthixol::Flupenthixol, Beta D(2) dopamine receptor Rattus norvegicus 300 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281878 103936541 968 ZINC28643021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173691 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Rattus norvegicus 26 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173694 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 39 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173695 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 775 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173696 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 35 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173697 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Rattus norvegicus 270 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173698 Cc1ccc(cc1)C1(O)CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C22H26FNO2/c1-17-4-8-19(9-5-17)22(26)12-15-24(16-13-22)14-2-3-21(25)18-6-10-20(23)11-7-18/h4-11,26H,2-3,12-16H2,1H3 AGAHNABIDCTLHW-UHFFFAOYSA-N 81486 CAS_1050-79-9::MOPERONE::NSC_4249 D(2) dopamine receptor Rattus norvegicus 880 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81486&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4249 131342060 ZINC00538026 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173700 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173702 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 460 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173704 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Rattus norvegicus 23 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173706 NCC(O)c1ccc(O)c(O)c1 InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2 SFLSHLFXELFNJZ-UHFFFAOYSA-N 35234 DL-[7-3H]norepinephrine::NOREPINEPHRINE::Noradrenaline,(+)::[3H]NE D(2) dopamine receptor Rattus norvegicus 2250 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35234&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LNR 3HCD,4Y4J,6M2R,3DYE,6M0Z,2QEO,4PAH 951 85753313 33569 484 ZINC00057624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173708 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Rattus norvegicus 220 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173709 Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C InChI=1S/C16H24N2O/c1-10-8-13(16(3,4)5)15(19)11(2)12(10)9-14-17-6-7-18-14/h8,19H,6-7,9H2,1-5H3,(H,17,18) WYWIFABBXFUGLM-UHFFFAOYSA-N 30712 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethyl-phenol;hydrochloride::6-tert-butyl-3-(4,5-dihydro-1H-imidazol-2-ylmethyl)-2,4-dimethylphenol;hydrochloride::MLS000038040::Oxymetazoline::SMR000059324::cid_66259 D(2) dopamine receptor Rattus norvegicus 1256 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30712&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search J5C 7EJK 4636 252614969 DB00935 C07363 ZINC00057435 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173710 Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19) MRBDMNSDAVCSSF-UHFFFAOYSA-N 31046 3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430 D(2) dopamine receptor Rattus norvegicus 3000 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5775 252615298 DB00692 ZINC00020251 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173711 CCN(CC)CCNC(=O)c1ccc(N)cc1 InChI=1S/C13H21N3O/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17) REQCZEXYDRLIBE-UHFFFAOYSA-N 39344 4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride::4-azanyl-N-[2-(diethylamino)ethyl]benzamide;hydrochloride::MLS000069436::PROCAINAMIDE::PROCAINAMIDE HYDROCHLORIDE::SMR000059079::cid_66068 D(2) dopamine receptor Rattus norvegicus 2500 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4913 252620239 DB01035 C07401 ZINC01530756 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173712 C1CN(CCN1)c1ccc2ccccc2n1 InChI=1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2 XRXDAJYKGWNHTQ-UHFFFAOYSA-N 50014407 2-(piperazin-1-yl)quinoline::2-Piperazin-1-yl-quinoline::2-Piperazin-1-yl-quinoline (Quipazine)::2-Piperazin-1-yl-quinoline(Quipazine)::CHEMBL18772::QUIPAZINE D(2) dopamine receptor Rattus norvegicus 3920 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014407&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5011 103926392 CHEMBL18772 173 ZINC19376338 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173713 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 880 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173716 CN1C[C@H](CSc2ccccn2)C[C@@H]2Cc3c(O)cccc3C[C@@H]12 InChI=1S/C20H24N2OS/c1-22-12-14(13-24-20-7-2-3-8-21-20)9-16-10-17-15(11-18(16)22)5-4-6-19(17)23/h2-8,14,16,18,23H,9-13H2,1H3/t14-,16-,18-/m1/s1 OZUQRMYHPWAQQC-QGPMSJSTSA-N 85047 SDZ GLC 756 D(2) dopamine receptor Rattus norvegicus 7 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840900 136351147 ZINC03826945 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173718 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 15 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173719 O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26) JVGBTTIJPBFLTE-UHFFFAOYSA-N 50020192 8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine D(2) dopamine receptor Rattus norvegicus 68 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5268 103931109 CHEMBL300555 53 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173722 CCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1 BGRJTUBHPOOWDU-LLVKDONJSA-N 81775 Sulpiride-R::Sulpiride-d::Sulpiride-high,(-)::Sulpiride-low,(-) D(2) dopamine receptor Rattus norvegicus 4284 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 643497 131342349 64122 960 ZINC00020229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173725 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 7342 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173726 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 160 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173727 CCCN1CCCC2Cc3c(CC12)ccc(O)c3O InChI=1S/C16H23NO2/c1-2-7-17-8-3-4-12-9-13-11(10-14(12)17)5-6-15(18)16(13)19/h5-6,12,14,18-19H,2-4,7-10H2,1H3 HZPDHOOVQQYBJP-UHFFFAOYSA-N 85049 TL304 D(2) dopamine receptor Rattus norvegicus 5320 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10332890 136351149 ZINC87722589 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173728 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Rattus norvegicus 850 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173729 OC1(CCN(CC1)C(F)CCC(=O)c1ccccc1)c1cccc(c1)C(F)(F)F InChI=1S/C22H23F4NO2/c23-20(10-9-19(28)16-5-2-1-3-6-16)27-13-11-21(29,12-14-27)17-7-4-8-18(15-17)22(24,25)26/h1-8,15,20,29H,9-14H2 ZIRLJRABDORTEO-UHFFFAOYSA-N 81493 CAS_749-13-3::TRIFLUORPERIDOL D(2) dopamine receptor Rattus norvegicus 200 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21514163 131342067 ZINC70463268 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173730 COc1ccccc1N1CCN(CCCNc2c(C)c(=O)n(C)c(=O)n2C)CC1 InChI=1S/C21H31N5O3/c1-16-19(23(2)21(28)24(3)20(16)27)22-10-7-11-25-12-14-26(15-13-25)17-8-5-6-9-18(17)29-4/h5-6,8-9,22H,7,10-15H2,1-4H3 HIHZDNKKIUQQSC-UHFFFAOYSA-N 50033112 6-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propylamino}-1,3,5-trimethyl-1H-pyrimidine-2,4-dione::CHEMBL420060::Urapidil-5-methyl D(2) dopamine receptor Rattus norvegicus 969 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033112&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5640 103941453 CHEMBL420060 489 ZINC02012436 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173731 COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccccc1 InChI=1S/C25H27NO5/c1-27-21-13-8-14-22(28-2)25(21)29-16-15-26-17-23-24(18-9-4-3-5-10-18)31-20-12-7-6-11-19(20)30-23/h3-14,23-24,26H,15-17H2,1-2H3 UVEKKXRFQCNLQE-UHFFFAOYSA-N 81444 CAS_185453::NSC_185453::WB 4101::WB-4101 D(2) dopamine receptor Rattus norvegicus 237 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14743454 131342018 ZINC14953628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173732 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 BLGXFZZNTVWLAY-SCYLSFHTSA-N 50013515 (+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester D(2) dopamine receptor Rattus norvegicus 926 PDSP Ki 10.1002/(SICI)1098-2396(199702)25:2 10.7270/Q2WH2NH6 9021894 Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH University of Toronto http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8969 103925641 48565 CHEMBL15245 DB01392 102 C09256 ZINC03860825 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175177 CN(C)C1CCc2[nH]c3ccc(NC(=O)c4ccc(F)cc4)cc3c2C1 InChI=1S/C21H22FN3O/c1-25(2)16-8-10-20-18(12-16)17-11-15(7-9-19(17)24-20)23-21(26)13-3-5-14(22)6-4-13/h3-7,9,11,16,24H,8,10,12H2,1-2H3,(H,23,26) GKWHICIUSVVNGX-UHFFFAOYSA-N 85195 CAS_5311097::LY 344864::NSC_5311097 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/s0024-3205(97)00885-0 10.7270/Q2F47MNN 9395253 Phebus, LA; Johnson, KW; Zgombick, JM; Gilbert, PJ; Van Belle, K; Mancuso, V; Nelson, DL; Calligaro, DO; Kiefer, AD; Branchek, TA; Flaugh, ME Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18971832 136351295 21 ZINC13831212 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173979 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 82 PDSP Ki 10.7270/Q20863TN 9103528 Tang, AH; Franklin, SR; Himes, CS; Smith, MW; Tenbrink, RE Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173980 Fc1ccc(cc1)N1CCN(CCC2OCCc3ccccc23)CC1 InChI=1S/C21H25FN2O/c22-18-5-7-19(8-6-18)24-14-12-23(13-15-24)11-9-21-20-4-2-1-3-17(20)10-16-25-21/h1-8,21H,9-16H2 UKOCGOXTVCIACM-UHFFFAOYSA-N 85067 CAS_170856-41-4::CHEMBL81330::PNU 96415E::PNU-96415E D(2) dopamine receptor Rattus norvegicus 199 PDSP Ki 10.7270/Q20863TN 9103528 Tang, AH; Franklin, SR; Himes, CS; Smith, MW; Tenbrink, RE Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9909648 136351167 CHEMBL81330 ZINC04632523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 174125 CC(N)Cc1c[nH]c2ccc(OCc3cccs3)cc12 InChI=1S/C16H18N2OS/c1-11(17)7-12-9-18-16-5-4-13(8-15(12)16)19-10-14-3-2-6-20-14/h2-6,8-9,11,18H,7,10,17H2,1H3 ALFGDCNSEBJYSP-UHFFFAOYSA-N 82472 BW-723C86::CAS_5311036::NSC_5311036 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/s0028-3908(96)00171-2 10.7270/Q2GB22KM 9144661 Kennett, GA; Ainsworth, K; Trail, B; Blackburn, TP SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4284720 136350443 ZINC03995822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173025 Cc1nc2C(O)CCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3 PMXMIIMHBWHSKN-UHFFFAOYSA-N 50252513 3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::9-OH-risperidone::9-hydroxy risperidone::CHEMBL1621::Invega::PALIPERIDONE D(2) dopamine receptor Rattus norvegicus 4 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search K4I 115237 104105311 CHEMBL1621 DB01267 7258 ZINC04214700 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173026 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 1.3 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173027 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 150 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173028 Fc1ccc(cc1)C(CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1)c1ccc(F)cc1 InChI=1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35) QOYHHIBFXOOADH-UHFFFAOYSA-N 26948 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL46516::FLUSPIRILENE::NCGC00015424::cid_3396::med.21724, Compound Fluspirilene::spiropiperidine analogue, 1 D(2) dopamine receptor Rattus norvegicus 1.5 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3396 57298659 CHEMBL46516 DB04842 85 ZINC00537755 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173029 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.4 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173030 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Rattus norvegicus 17 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173031 CN1CC2C(C1)c1cc(Cl)ccc1Oc1ccccc21 InChI=1S/C17H16ClNO/c1-19-9-14-12-4-2-3-5-16(12)20-17-7-6-11(18)8-13(17)15(14)10-19/h2-8,14-15H,9-10H2,1H3 VSWBSWWIRNCQIJ-UHFFFAOYSA-N 84994 CAS_163091::NSC_163091::ORG-5222 D(2) dopamine receptor Rattus norvegicus 2 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903970 136351094 71255 DB06216 ZINC11677376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173032 NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N1CCCCC1 InChI=1S/C21H30FN3O2/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25/h6-9H,1-5,10-16H2,(H2,23,27) AXKPFOAXAHJUAG-UHFFFAOYSA-N 81483 CAS_1893-33-0::NSC_4830::PIPAMPERONE D(2) dopamine receptor Rattus norvegicus 93 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4830 131342057 DB09286 92 ZINC21297287 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173033 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Rattus norvegicus 310 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173034 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3.3 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173035 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Rattus norvegicus 7.4 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173036 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Rattus norvegicus 9.7 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173037 CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3 HDOZVRUNCMBHFH-UHFFFAOYSA-N 35255 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin::2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin::2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine::CHEMBL285802::Nipolept::Zoleptil::zotepine D(2) dopamine receptor Rattus norvegicus 13 PDSP Ki 10.1007/bf02245606 10.7270/Q2610XV6 8935801 Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Janssen Research Foundation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ZOT 6A94 5736 85753334 32316 CHEMBL285802 DB09225 103 ZINC00002264 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175563 CCNC(=O)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 InChI=1S/C23H29F2N3O/c1-2-26-23(29)28-16-14-27(15-17-28)13-3-4-22(18-5-9-20(24)10-6-18)19-7-11-21(25)12-8-19/h5-12,22H,2-4,13-17H2,1H3,(H,26,29) NNAIYOXJNVGUOM-UHFFFAOYSA-N 50311786 Amperozide::CHEMBL1079935 D(2) dopamine receptor Rattus norvegicus 140 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50311786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50311786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73333 104146147 CHEMBL1079935 DB08927 ZINC04214849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175564 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 36 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175565 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 36 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175566 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.82 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175567 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.82 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175568 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Rattus norvegicus 2.1 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175569 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Rattus norvegicus 2.1 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175570 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Rattus norvegicus 69 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175571 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Rattus norvegicus 69 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175572 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Rattus norvegicus 2000 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175573 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Rattus norvegicus 2000 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175574 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 0.44 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175575 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 0.44 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175576 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Rattus norvegicus 0.45 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175577 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Rattus norvegicus 0.45 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175578 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Rattus norvegicus 2.8 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 175579 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Rattus norvegicus 2.8 PDSP Ki 10.1016/S0893-133X(97)00112-7 10.7270/Q2SF2TQB 9430133 Arnt, J; Skarsfeldt, T H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173347 NS(=O)(=O)c1ccc(cc1)N1CCN(CC[C@H]2OCCc3ccccc23)CC1 InChI=1S/C21H27N3O3S/c22-28(25,26)19-7-5-18(6-8-19)24-14-12-23(13-15-24)11-9-21-20-4-2-1-3-17(20)10-16-27-21/h1-8,21H,9-16H2,(H2,22,25,26)/t21-/m1/s1 WNUQCGWXPNGORO-OAQYLSRUSA-N 50051563 4-[4-((R)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]-benzenesulfonamide::CHEMBL81649::U-101387 D(2) dopamine receptor Rattus norvegicus 5147 PDSP Ki 10.7270/Q2SQ8XX9 8968364 Merchant, KM; Gill, GS; Harris, DW; Huff, RM; Eaton, MJ; Lookingland, K; Lutzke, BS; Mccall, RB; Piercey, MF; Schreur, PJ; Sethy, VH; Smith, MW; Svensson, KA; Tang, AH; Vonvoigtlander, PF; Tenbrink, RE Pharmacia and Upjohn, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811059 103948558 CHEMBL81649 ZINC05162669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173408 CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21) NTJOBXMMWNYJFB-UHFFFAOYSA-N 81790 Amisulpride::CAS_71675-85-9::NSC_2159::US10167256, Amisulpride::US10259786, Amisulpride D(2) dopamine receptor Rattus norvegicus 21 PDSP Ki 10.7270/Q2NZ865X 8996185 Schoemaker, H; Claustre, Y; Fage, D; Rouquier, L; Chergui, K; Curet, O; Oblin, A; Gonon, F; Carter, C; Benavides, J; Scatton, B Synthélabo Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2159 131342364 64045 DB06288 963 ZINC01846088 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173409 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 430 PDSP Ki 10.7270/Q2NZ865X 8996185 Schoemaker, H; Claustre, Y; Fage, D; Rouquier, L; Chergui, K; Curet, O; Oblin, A; Gonon, F; Carter, C; Benavides, J; Scatton, B Synthélabo Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 173410 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2 PDSP Ki 10.7270/Q2NZ865X 8996185 Schoemaker, H; Claustre, Y; Fage, D; Rouquier, L; Chergui, K; Curet, O; Oblin, A; Gonon, F; Carter, C; Benavides, J; Scatton, B Synthélabo Recherche http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178588 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 69.9 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178589 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 380 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178590 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 9.4 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178591 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 2.67 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178592 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 4.37 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178593 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178594 Cc1c(O)ccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1C InChI=1S/C25H33N3O3/c1-18-19(2)24(29)9-8-23(18)28-14-12-27(13-15-28)11-3-4-16-31-21-7-5-20-6-10-25(30)26-22(20)17-21/h5,7-9,17,29H,3-4,6,10-16H2,1-2H3,(H,26,30) PAUGKXWLDIKBPI-UHFFFAOYSA-N 85413 7-{4-[4-(4-hydroxy-2,3-dimethylphenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one::DM 1451 D(2) dopamine receptor Rattus norvegicus 0.21 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85413&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56947066 136351513 ZINC87722819 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178595 Cc1c(O)ccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1C InChI=1S/C25H33N3O3/c1-18-19(2)24(29)9-8-23(18)28-14-12-27(13-15-28)11-3-4-16-31-21-7-5-20-6-10-25(30)26-22(20)17-21/h5,7-9,17,29H,3-4,6,10-16H2,1-2H3,(H,26,30) PAUGKXWLDIKBPI-UHFFFAOYSA-N 85413 7-{4-[4-(4-hydroxy-2,3-dimethylphenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one::DM 1451 D(2) dopamine receptor Rattus norvegicus 0.96 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85413&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56947066 136351513 ZINC87722819 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178596 Cc1c(O)ccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1C InChI=1S/C25H33N3O3/c1-18-19(2)24(29)9-8-23(18)28-14-12-27(13-15-28)11-3-4-16-31-21-7-5-20-6-10-25(30)26-22(20)17-21/h5,7-9,17,29H,3-4,6,10-16H2,1-2H3,(H,26,30) PAUGKXWLDIKBPI-UHFFFAOYSA-N 85413 7-{4-[4-(4-hydroxy-2,3-dimethylphenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one::DM 1451 D(2) dopamine receptor Rattus norvegicus 4.1 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85413&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56947066 136351513 ZINC87722819 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178597 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.07 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178598 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.22 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178599 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.79 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178600 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.41 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178601 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Rattus norvegicus 0.52 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178602 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Rattus norvegicus 1.71 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178603 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Rattus norvegicus 4.7 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178604 Cc1cccc(N2CCN(CCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1C InChI=1S/C24H29N3O2/c1-18-5-3-6-23(19(18)2)27-14-12-26(13-15-27)11-4-16-29-21-9-7-20-8-10-24(28)25-22(20)17-21/h3,5-10,17H,4,11-16H2,1-2H3,(H,25,28) RRLWEQBPSAFVAS-UHFFFAOYSA-N 82065 CAS_163839::NSC_163839::OPC-4392 D(2) dopamine receptor Rattus norvegicus 3.5 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 163839 131342639 268 ZINC05116306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178605 Cc1cccc(N2CCN(CCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1C InChI=1S/C24H29N3O2/c1-18-5-3-6-23(19(18)2)27-14-12-26(13-15-27)11-4-16-29-21-9-7-20-8-10-24(28)25-22(20)17-21/h3,5-10,17H,4,11-16H2,1-2H3,(H,25,28) RRLWEQBPSAFVAS-UHFFFAOYSA-N 82065 CAS_163839::NSC_163839::OPC-4392 D(2) dopamine receptor Rattus norvegicus 90.9 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 163839 131342639 268 ZINC05116306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178606 Cc1cccc(N2CCN(CCCOc3ccc4ccc(=O)[nH]c4c3)CC2)c1C InChI=1S/C24H29N3O2/c1-18-5-3-6-23(19(18)2)27-14-12-26(13-15-27)11-4-16-29-21-9-7-20-8-10-24(28)25-22(20)17-21/h3,5-10,17H,4,11-16H2,1-2H3,(H,25,28) RRLWEQBPSAFVAS-UHFFFAOYSA-N 82065 CAS_163839::NSC_163839::OPC-4392 D(2) dopamine receptor Rattus norvegicus 88 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 163839 131342639 268 ZINC05116306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178607 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 47 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178608 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.07 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178609 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.26 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178610 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 0.21 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178611 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 78 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181073 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 0.05 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181074 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) BVPWJMCABCPUQY-UHFFFAOYSA-N 50132693 4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide(Clebopride)::4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide::CHEMBL325109::Clebopride D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2780 104023670 CHEMBL325109 ZINC00608261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181075 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 88 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181076 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.2 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181077 OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 PLDUPXSUYLZYBN-UHFFFAOYSA-N 78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17 D(2) dopamine receptor Rattus norvegicus 0.25 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3372 252655189 DB00623 C07010 ZINC19203912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181078 OCCN1CCN(CC\C=C2\c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C23H25F3N2OS/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29/h1-2,4-8,16,29H,3,9-15H2/b18-5- NJMYODHXAKYRHW-DVZOWYKESA-N 79172 2-[4-[(3Z)-3-[2-(trifluoromethyl)-9-thioxanthenylidene]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[(3Z)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[(3Z)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazino]ethanol;hydrochloride::Fluphenthixol::MLS001332581::SMR000875208::cid_10140115::cis-(Z)-Flupenthixol dihydrochloride D(2) dopamine receptor Rattus norvegicus 0.25 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281881 252655887 C11191 ZINC29489118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181079 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.44 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181080 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 2705 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181081 Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 InChI=1S/C17H19N3O/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15/h2-8,11,21H,9-10,12H2,1H3,(H,18,19) MRBDMNSDAVCSSF-UHFFFAOYSA-N 31046 3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride::3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid::3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid::MLS000069487::PHENTOLAMINE::PHENTOLAMINE MESYLATE::SMR000059054::cid_5775::cid_91430 D(2) dopamine receptor Rattus norvegicus 1772 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5775 252615298 DB00692 ZINC00020251 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181082 CC(C)NCC(O)COc1cccc2[nH]ccc12 InChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3 JZQKKSLKJUAGIC-UHFFFAOYSA-N 50019443 1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol::1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol((-)-Pindolol)::1-(1H-Indol-4-yloxy)-3-isopropylamino-propan-2-ol(pindolol)::1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol::LB-46::PINDOLOL::PINDOLOL,(-)::PRINODOLOL::VISKAZIDE::VISKEN D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4828 103930398 8214 DB00960 91 C07445 ZINC00056646 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181083 CC(C)NCC(O)COc1cccc2ccccc12 InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3 AQHHHDLHHXJYJD-UHFFFAOYSA-N 25761 Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SNP 1DY4,6EKZ,6PS5,5FUK 4946 56413049 8499 CHEMBL27 DB00571 564 C07407 ZINC00056556 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181084 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 569 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181085 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.01 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181086 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 6.4 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181087 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Rattus norvegicus 0.41 PDSP Ki 10.1002/1098-2396(20001215)38:4 10.7270/Q2SN07HX 11044891 Luedtke, RR; Freeman, RA; Boundy, VA; Martin, MW; Huang, Y; Mach, RH University of North Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178612 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 340 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178613 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Rattus norvegicus 0.59 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 178614 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.07 PDSP Ki 10.1016/S0893-133X(98)00099-2 10.7270/Q2ZP44NW 10327430 Lawler, CP; Prioleau, C; Lewis, MM; Mak, C; Jiang, D; Schetz, JA; Gonzalez, AM; Sibley, DR; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 182427 CC(CF)NCC(O)COc1cccc2[nH]c3ccccc3c12 InChI=1S/C18H21FN2O2/c1-12(9-19)20-10-13(22)11-23-17-8-4-7-16-18(17)14-5-2-3-6-15(14)21-16/h2-8,12-13,20-22H,9-11H2,1H3 QHLGXPUIUKSADT-UHFFFAOYSA-N 85818 Fluorocarazolol,(R)::Fluorocarazolol,(S) D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s002130100844 10.7270/Q22V2DPJ 11512051 Roth, BL; Ernsberger, P; Steinberg, SA; Rao, S; Rauser, L; Savage, J; Hufeisen, S; Berridge, MS; Muzic, RF Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133038 136351918 ZINC06036510 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 182428 CC(CF)NCC(O)COc1cccc2[nH]c3ccccc3c12 InChI=1S/C18H21FN2O2/c1-12(9-19)20-10-13(22)11-23-17-8-4-7-16-18(17)14-5-2-3-6-15(14)21-16/h2-8,12-13,20-22H,9-11H2,1H3 QHLGXPUIUKSADT-UHFFFAOYSA-N 85818 Fluorocarazolol,(R)::Fluorocarazolol,(S) D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s002130100844 10.7270/Q22V2DPJ 11512051 Roth, BL; Ernsberger, P; Steinberg, SA; Rao, S; Rauser, L; Savage, J; Hufeisen, S; Berridge, MS; Muzic, RF Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133038 136351918 ZINC06036510 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 180051 Fc1cccc2OC3CNCC3Oc12 InChI=1S/C10H10FNO2/c11-6-2-1-3-7-10(6)14-9-5-12-4-8(9)13-7/h1-3,8-9,12H,4-5H2 XSOUHEXVEOQRKJ-UHFFFAOYSA-N 85595 CAS_105182-45-4::Fluparoxan::NSC_72036 D(2) dopamine receptor Rattus norvegicus 3162.27 PDSP Ki 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X 10.7270/Q2XK8D4N 10611634 Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10219795 136351695 41 ZINC11680328 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 180052 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.99 PDSP Ki 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X 10.7270/Q2XK8D4N 10611634 Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 180054 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 BLGXFZZNTVWLAY-SCYLSFHTSA-N 50013515 (+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester D(2) dopamine receptor Rattus norvegicus 501.18 PDSP Ki 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X 10.7270/Q2XK8D4N 10611634 Millan, MJ; Newman-Tancredi, A; Audinot, V; Cussac, D; Lejeune, F; Nicolas, JP; Coge, F; Galizzi, JP; Boutin, JA; Rivet, JM; Dekeyne, A; Gobert, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8969 103925641 48565 CHEMBL15245 DB01392 102 C09256 ZINC03860825 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181230 Nc1ncnc2nc(cc(-c3cccc(Br)c3)c12)-c1ccc(nc1)N1CCOCC1 InChI=1S/C22H19BrN6O/c23-16-3-1-2-14(10-16)17-11-18(28-22-20(17)21(24)26-13-27-22)15-4-5-19(25-12-15)29-6-8-30-9-7-29/h1-5,10-13H,6-9H2,(H2,24,26,27,28) RQCXKDWOCUJWQZ-UHFFFAOYSA-N 50094703 5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine::5-(3-bromophenyl)-7-(6-morpholin-4-ylpyridin-3-yl)pyrido[2,3-d]pyrimidin-4-ylamine::ABT-702::CHEMBL66089 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.7270/Q2DF6PSP 11082453 Jarvis, MF; Yu, H; Kohlhaas, K; Alexander, K; Lee, CH; Jiang, M; Bhagwat, SS; Williams, M; Kowaluk, EA Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094703&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1973 103992579 CHEMBL66089 5131 ZINC21288919 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 179148 CN(C)CCC=C1c2ccccc2CCc2ccccc12 InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3 KRMDCWKBEZIMAB-UHFFFAOYSA-N 50020712 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene::10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine::3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine::3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine::3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine::5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene::5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene::5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene::AMITRIPTYLINE::Amitriptylin::CHEMBL629 D(2) dopamine receptor Rattus norvegicus 850 PDSP Ki 10.1023/a:1006986824213 10.7270/Q2WQ02CP 10379421 Sanchez, C; Hyttel, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020712&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TP0 8Y93,5HA9,3APV 2160 103931468 2666 CHEMBL629 DB00321 200 C06824 ZINC00968257 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 179149 CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3 SNPPWIUOZRMYNY-UHFFFAOYSA-N 50048392 2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one::BUPROPION::BUPROPION HYDROCHLORIDE::CHEMBL894::US9944618, Compound ID No. 176 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1023/a:1006986824213 10.7270/Q2WQ02CP 10379421 Sanchez, C; Hyttel, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048392&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 444 103978858 3219 CHEMBL894 DB01156 7135 C06860 ZINC00057206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 179150 CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1 InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3 WSEQXVZVJXJVFP-UHFFFAOYSA-N 25870 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile::CHEMBL549::CITALOPRAM::CITALOPRAM HYDROBROMIDE::Escitalopram::[3H]Citalopram::[3H]Cytalopram::[3H]Escitalopram::[3H]Lexapro D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1023/a:1006986824213 10.7270/Q2WQ02CP 10379421 Sanchez, C; Hyttel, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68P 5I73,5I71,5I75 2771 56413158 3723 CHEMBL549 DB00215 4621 C07572 ZINC03800706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 179151 CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1 InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3 RTHCYVBBDHJXIQ-UHFFFAOYSA-N 30130 CHEMBL1201082::CHEMBL41::Fluoxetin::Fluoxetine::Prozac::US9120771, Fluoxetine::cid_62857 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1023/a:1006986824213 10.7270/Q2WQ02CP 10379421 Sanchez, C; Hyttel, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30130&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search RFX 4MM8,3GWV 3386 85147891 5118 CHEMBL1201082CHEMBL41 DB00472 203 ZINC01530638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 179152 COCCCC\C(=N/OCCN)c1ccc(cc1)C(F)(F)F InChI=1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18/h5-8H,2-4,9-11,19H2,1H3/b20-14+ CJOFXWAVKWHTFT-XSFVSMFZSA-N 50028091 (1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one O-(2-aminoethyl)oxime::CHEMBL814::FLUVOXAMINE D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1023/a:1006986824213 10.7270/Q2WQ02CP 10379421 Sanchez, C; Hyttel, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028091&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search FVX 6AWP,4MM9,4ENH 5324346 103937470 5138 CHEMBL814 7189 C07571 ZINC03872605 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 179153 CN(CCCN1c2ccccc2CCc2ccccc12)CC(=O)c1ccc(Cl)cc1 InChI=1S/C26H27ClN2O/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3 SAPNXPWPAUFAJU-UHFFFAOYSA-N 82437 CAS_23047-25-8::Lofepramine::NSC_3947::US8629135, SW-06 D(2) dopamine receptor Rattus norvegicus 6700 PDSP Ki 10.1023/a:1006986824213 10.7270/Q2WQ02CP 10379421 Sanchez, C; Hyttel, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82437&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3947 136350408 47782 ZINC01542929 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 179154 CCc1nn(CCCN2CCN(CC2)c2cccc(Cl)c2)c(=O)n1CCOc1ccccc1 InChI=1S/C25H32ClN5O2/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22/h3-6,8-11,20H,2,7,12-19H2,1H3 VRBKIVRKKCLPHA-UHFFFAOYSA-N 50069447 1-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one::2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-ethyl-4-(2-phenoxyethyl)-2,4-dihydro-3H-1,2,4-triazol-3-one::CHEMBL623::NEFAZODONE::US9138393, Nefazodone HCl::US9144538, Nefazodone HCl D(2) dopamine receptor Rattus norvegicus 180 PDSP Ki 10.1023/a:1006986824213 10.7270/Q2WQ02CP 10379421 Sanchez, C; Hyttel, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4449 103963508 7494 CHEMBL623 DB01149 7247 C07256 ZINC00538065 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 179155 Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1 InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 22416 (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine::(3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine::CHEMBL490::PAROXETINE::US09969700, Paroxetine::US9944618, Compound ID No. 182::[3H]Paroxetine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1023/a:1006986824213 10.7270/Q2WQ02CP 10379421 Sanchez, C; Hyttel, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22416&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8PR 6F6I,7OIH,6DZW,6AWN,4JLT,3V5W,4MM4,6VRH,5I6X,4L9I 43815 49846231 7936 CHEMBL490 DB00715 4561 C07415 ZINC00527386 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 179156 CN[C@@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c2ccccc12 InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17+/m0/s1 VGKDLMBJGBXTGI-YVEFUNNKSA-N 82217 CHEMBL284994::CP-52003::SERTRALINE::[4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-methyl-amine D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1023/a:1006986824213 10.7270/Q2WQ02CP 10379421 Sanchez, C; Hyttel, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82217&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9882979 136350189 CHEMBL284994 ZINC03831445 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 179157 COc1ccc(cc1)C(CN(C)C)C1(O)CCCCC1 InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3 PNVNVHUZROJLTJ-UHFFFAOYSA-N 82071 CAS_93413-69-5::CAS_99300-78-4::NSC_62923::VENLAFAXINE::Venlafaxine hydrochloride::WY-45030::WY-45655 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1023/a:1006986824213 10.7270/Q2WQ02CP 10379421 Sanchez, C; Hyttel, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82071&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search VFX 8F4W 5656 131342645 DB00285 C07187 ZINC00896698 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181749 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 35 PDSP Ki 10.7270/Q2BG2MJX 11171942 Strange, PG University of Reading http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181750 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.53 PDSP Ki 10.7270/Q2BG2MJX 11171942 Strange, PG University of Reading http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181751 CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 WXPNDRBBWZMPQG-UHFFFAOYSA-N 82479 CAS_132539-06-1::NSC_4585::OLANZAPINE::USRE49340, Rank 2 D(2) dopamine receptor Rattus norvegicus 7.5 PDSP Ki 10.7270/Q2BG2MJX 11171942 Strange, PG University of Reading http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 136350450 47 ZINC03873830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181752 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Rattus norvegicus 105 PDSP Ki 10.7270/Q2BG2MJX 11171942 Strange, PG University of Reading http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181753 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1 PDSP Ki 10.7270/Q2BG2MJX 11171942 Strange, PG University of Reading http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181754 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Rattus norvegicus 54 PDSP Ki 10.7270/Q2BG2MJX 11171942 Strange, PG University of Reading http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181755 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 1.3 PDSP Ki 10.7270/Q2BG2MJX 11171942 Strange, PG University of Reading http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181756 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Rattus norvegicus 0.38 PDSP Ki 10.7270/Q2BG2MJX 11171942 Strange, PG University of Reading http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181757 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 2.5 PDSP Ki 10.7270/Q2BG2MJX 11171942 Strange, PG University of Reading http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 181758 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.7270/Q2BG2MJX 11171942 Strange, PG University of Reading http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 182027 C(N1CCN(CC1)c1ncccn1)c1ccc2OCOc2c1 InChI=1S/C16H18N4O2/c1-4-17-16(18-5-1)20-8-6-19(7-9-20)11-13-2-3-14-15(10-13)22-12-21-14/h1-5,10H,6-9,11-12H2 OQDPVLVUJFGPGQ-UHFFFAOYSA-N 85092 CAS_3605-01-4::NSC_4850::Piribedil D(2) dopamine receptor Rattus norvegicus 181.97 PDSP Ki 10.7270/Q2W957RF 11356907 Millan, MJ; Cussac, D; Milligan, G; Carr, C; Audinot, V; Gobert, A; Lejeune, F; Rivet, JM; Brocco, M; Duqueyroix, D; Nicolas, JP; Boutin, JA; Newman-Tancredi, A Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4850 136351192 ZINC19537374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 180871 CCCN(CCC)C1CCc2cc(CS(=O)(=O)c3ccc(OC)cc3)ccc2C1 InChI=1S/C24H33NO3S/c1-4-14-25(15-5-2)22-9-8-20-16-19(6-7-21(20)17-22)18-29(26,27)24-12-10-23(28-3)11-13-24/h6-7,10-13,16,22H,4-5,8-9,14-15,17-18H2,1-3H3 HUXFXXWYIRBVJR-UHFFFAOYSA-N 50240797 6-((4-methoxyphenylsulfonyl)methyl)-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine::CHEMBL334529::GR-218231::GR218231::[6-(4-Methoxy-benzenesulfonylmethyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dipropyl-amine D(2) dopamine receptor Rattus norvegicus 79.43 PDSP Ki 10.7270/Q2ZC81DX 10869410 Millan, MJ; Gobert, A; Newman-Tancredi, A; Lejeune, F; Cussac, D; Rivet, JM; Audinot, V; Dubuffet, T; Lavielle, G Centre de Recherches de Croissy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24840389 104098462 CHEMBL334529 ZINC06013412 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 180874 OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1 InChI=1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2 LLBLNMUONVVVPG-UHFFFAOYSA-N 50050467 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol::3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole::4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol::CHEMBL445102::L-741626::L741,626 D(2) dopamine receptor Rattus norvegicus 6.31 PDSP Ki 10.7270/Q2ZC81DX 10869410 Millan, MJ; Gobert, A; Newman-Tancredi, A; Lejeune, F; Cussac, D; Rivet, JM; Audinot, V; Dubuffet, T; Lavielle, G Centre de Recherches de Croissy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133633 103947637 CHEMBL445102 177 ZINC00006788 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 180877 O=C(NCCCCN1C[C@@H]2COc3ccc(cc3[C@H]2C1)C#N)c1ccc(cc1)-c1ccccc1 InChI=1S/C29H29N3O2/c30-17-21-8-13-28-26(16-21)27-19-32(18-25(27)20-34-28)15-5-4-14-31-29(33)24-11-9-23(10-12-24)22-6-2-1-3-7-22/h1-3,6-13,16,25,27H,4-5,14-15,18-20H2,(H,31,33)/t25-,27+/m1/s1 QQJHRQZZCNYDMX-VPUSJEBWSA-N 85672 S33084 D(2) dopamine receptor Rattus norvegicus 50.12 PDSP Ki 10.7270/Q2ZC81DX 10869410 Millan, MJ; Gobert, A; Newman-Tancredi, A; Lejeune, F; Cussac, D; Rivet, JM; Audinot, V; Dubuffet, T; Lavielle, G Centre de Recherches de Croissy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9868452 136351772 ZINC03941217 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 180942 O=C(NC1CC[C@H](CCN2CCc3cc(ccc3C2)C#N)CC1)c1ccnc2ccccc12 InChI=1S/C28H30N4O/c29-18-21-5-8-23-19-32(16-13-22(23)17-21)15-12-20-6-9-24(10-7-20)31-28(33)26-11-14-30-27-4-2-1-3-25(26)27/h1-5,8,11,14,17,20,24H,6-7,9-10,12-13,15-16,19H2,(H,31,33)/t20-,24? OLWRVVHPJFLNPW-WVZUTIKQSA-N 50167898 CHEMBL85606::N-((1r,4r)-4-(2-(6-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)quinoline-4-carboxamide::N-(-4-(2-(6-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)quinoline-4-carboxamide::Quinoline-4-carboxylic acid {4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-cyclohexyl}-amide::SB-277011::SB-277011-A::trans-N-[4-[2-(6-cyano-1,2,3,4-tetrahydroisoquinolin-2yl)-ethyl]cyclo-hexyl]-4-quinolinecarboxamide::trans-N-[4-[2-(6-cyano-1,2,3,4-tetrahydroisoquinolin-2yl)ethyl]-cyclohexyl]-4-quinolininecarboxamide D(2) dopamine receptor Rattus norvegicus 2818.38 PDSP Ki 10.7270/Q2K35S7G 10945872 Reavill, C; Taylor, SG; Wood, MD; Ashmeade, T; Austin, NE; Avenell, KY; Boyfield, I; Branch, CL; Cilia, J; Coldwell, MC; Hadley, MS; Hunter, AJ; Jeffrey, P; Jewitt, F; Johnson, CN; Jones, DN; Medhurst, AD; Middlemiss, DN; Nash, DJ; Riley, GJ; Routledge, C; Stemp, G; Thewlis, KM; Trail, B; Vong, AK; Hagan, JJ SmithKline Beecham Pharmaceuticals Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167898&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311096 104053095 CHEMBL85606 143 ZINC26574567 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 184870 COc1ccc2ccccc2c1CCCCN1CCN(C[C@@H](N2CCN(CC2)C(C)C)c2ccc(F)cc2)CC1 InChI=1S/C34H47FN4O/c1-27(2)38-22-24-39(25-23-38)33(29-11-14-30(35)15-12-29)26-37-20-18-36(19-21-37)17-7-6-10-32-31-9-5-4-8-28(31)13-16-34(32)40-3/h4-5,8-9,11-16,27,33H,6-7,10,17-26H2,1-3H3/t33-/m1/s1 SLGLZEJKMBCODK-MGBGTMOVSA-N 86058 MCL0129 D(2) dopamine receptor Rattus norvegicus 1000 PDSP Ki 10.1124/jpet.102.044826 10.7270/Q2FQ9V5W 12538838 Chaki, S; Hirota, S; Funakoshi, T; Suzuki, Y; Suetake, S; Okubo, T; Ishii, T; Nakazato, A; Okuyama, S Taisho Pharmaceutical Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86058&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6918688 136352158 ZINC22453554 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187600 Oc1ccc2[C@@H]3CNCc4ccc(F)c(Cc2c1O)c34 InChI=1S/C16H14FNO2/c17-13-3-1-8-6-18-7-12-9-2-4-14(19)16(20)10(9)5-11(13)15(8)12/h1-4,12,18-20H,5-7H2/t12-/m0/s1 SEHKHMIKGHOJEI-LBPRGKRZSA-N 86463 (+)-6-fluorodinapsoline hydrobromide::CAS_0::NSC_0 D(2) dopamine receptor Rattus norvegicus 7 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86463&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340605 136352512 ZINC13479465 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187601 Oc1cc(Cl)c2[C@@H]3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H14ClNO2/c17-12-5-13(19)16(20)10-4-8-2-1-3-9-6-18-7-11(14(8)9)15(10)12/h1-3,5,11,18-20H,4,6-7H2/t11-/m1/s1 GDDGUUOQOYOFPC-LLVKDONJSA-N 86455 (+/-)-11-chlorodinapsoline hydrobromide::CAS_0::NSC_0 D(2) dopamine receptor Rattus norvegicus 16 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86455&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340597 136352504 ZINC13479444 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187602 Oc1cc(c2[C@@H]3CNCc4cccc(Cc2c1O)c34)N(=O)=O InChI=1S/C16H14N2O4/c19-13-5-12(18(21)22)15-10(16(13)20)4-8-2-1-3-9-6-17-7-11(15)14(8)9/h1-3,5,11,17,19-20H,4,6-7H2/t11-/m1/s1 SSSFLCBJDVGFJA-LLVKDONJSA-N 86469 (+/-)-11-nitrodinapsoline hydrobromide::CAS_0::NSC_0 D(2) dopamine receptor Rattus norvegicus 1100 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86469&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340610 136352518 C06058 ZINC13479447 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187604 CN1C[C@H]2c3ccc(O)c(O)c3Cc3cccc(C1)c23 InChI=1S/C17H17NO2/c1-18-8-11-4-2-3-10-7-13-12(14(9-18)16(10)11)5-6-15(19)17(13)20/h2-6,14,19-20H,7-9H2,1H3/t14-/m0/s1 QKJKRFHJKGBUTP-AWEZNQCLSA-N 86466 (+/-)-2-methyldinapsoline hydrobromide::CAS_0::NSC_0 D(2) dopamine receptor Rattus norvegicus 70 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340607 136352515 ZINC13479449 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187607 CCCCC1NC[C@H]2c3ccc(O)c(O)c3Cc3cccc1c23 InChI=1S/C20H23NO2/c1-2-3-7-17-14-6-4-5-12-10-15-13(8-9-18(22)20(15)23)16(11-21-17)19(12)14/h4-6,8-9,16-17,21-23H,2-3,7,10-11H2,1H3/t16-,17?/m0/s1 JESNJOJDSRVNBV-BHWOMJMDSA-N 86458 (+/-)-3-n-butyldinapsoline hydrobromide D(2) dopamine receptor Rattus norvegicus 93 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340600 136352507 ZINC13479457 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187608 Oc1ccc2[C@@H]3CNC(c4cccc(Cc2c1O)c34)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F InChI=1S/C20H14F9NO2/c21-17(22,18(23,24)19(25,26)20(27,28)29)16-10-3-1-2-8-6-11-9(4-5-13(31)15(11)32)12(7-30-16)14(8)10/h1-5,12,16,30-32H,6-7H2/t12-,16?/m0/s1 RCJRFPWQKVARQW-HKALDPMFSA-N 86470 (+/-)-3-perfluorobutyldinapsoline hydrobromide::CAS_0::NSC_0 D(2) dopamine receptor Rattus norvegicus 78 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340611 136352519 ZINC89464688 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187609 CC1(C)c2cccc3CNC[C@@H](c4ccc(O)c(O)c14)c23 InChI=1S/C18H19NO2/c1-18(2)13-5-3-4-10-8-19-9-12(15(10)13)11-6-7-14(20)17(21)16(11)18/h3-7,12,19-21H,8-9H2,1-2H3/t12-/m0/s1 NHTSDWPOZRWTAX-LBPRGKRZSA-N 86457 (+/-)-7,7'-dimethyldinapsoline hydrobromide::CAS_0::NSC_0 D(2) dopamine receptor Rattus norvegicus 390 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340599 136352506 ZINC13479434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187610 CCC1c2cccc3CNC[C@@H](c4ccc(O)c(O)c14)c23 InChI=1S/C18H19NO2/c1-2-11-12-5-3-4-10-8-19-9-14(16(10)12)13-6-7-15(20)18(21)17(11)13/h3-7,11,14,19-21H,2,8-9H2,1H3/t11?,14-/m0/s1 RPHXSTFLDZRMMM-IAXJKZSUSA-N 86460 (+/-)-7-ethyldinapsoline hydrobromide D(2) dopamine receptor Rattus norvegicus 440 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86460&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340602 136352509 ZINC13479438 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187611 COC(=O)CC1c2cccc3CNC[C@@H](c4ccc(O)c(O)c14)c23 InChI=1S/C19H19NO4/c1-24-16(22)7-13-11-4-2-3-10-8-20-9-14(17(10)11)12-5-6-15(21)19(23)18(12)13/h2-6,13-14,20-21,23H,7-9H2,1H3/t13?,14-/m0/s1 XBILGIMPJNNKOD-KZUDCZAMSA-N 86471 (+/-)-7-methoxycarbonylmethyldinapsoline D(2) dopamine receptor Rattus norvegicus 990 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340612 136352520 ZINC96135317 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187612 CC1c2cccc3CNC[C@@H](c4ccc(O)c(O)c14)c23 InChI=1S/C17H17NO2/c1-9-11-4-2-3-10-7-18-8-13(16(10)11)12-5-6-14(19)17(20)15(9)12/h2-6,9,13,18-20H,7-8H2,1H3/t9?,13-/m0/s1 HQWKOCKQSDIRSK-NCWAPJAISA-N 86465 (+/-)-7-methyldinapsoline hydrobromide D(2) dopamine receptor Rattus norvegicus 160 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340606 136352514 ZINC13479432 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187613 Oc1ccc2C3CNCc4ccc(F)c(Cc2c1O)c34 InChI=1S/C16H14FNO2/c17-13-3-1-8-6-18-7-12-9-2-4-14(19)16(20)10(9)5-11(13)15(8)12/h1-4,12,18-20H,5-7H2 SEHKHMIKGHOJEI-UHFFFAOYSA-N 86464 (-)-6-fluorodinapsoline hydrobromide::CAS_0::NSC_0 D(2) dopamine receptor Rattus norvegicus 170 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86464&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10423309 136352513 ZINC13479465 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187614 Oc1ccc2C3CNCc4cccc(Sc2c1O)c34 InChI=1S/C15H13NO2S/c17-11-5-4-9-10-7-16-6-8-2-1-3-12(13(8)10)19-15(9)14(11)18/h1-5,10,16-18H,6-7H2 BBDBLYVUGIMODC-UHFFFAOYSA-N 86461 1,2,3,11b-Tetrahydro[1]benzothiopyrano[4,3,2-de]isoquinolin-8,9-diol D(2) dopamine receptor Rattus norvegicus 34.5 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86461&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340603 136352510 ZINC13479427 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187615 Oc1ccc2c3cncc4c(F)ccc([nH]c2c1O)c34 InChI=1S/C15H9FN2O2/c16-10-2-3-11-13-8(5-17-6-9(10)13)7-1-4-12(19)15(20)14(7)18-11/h1-6,18-20H TYYMFSFOBIQMIB-UHFFFAOYSA-N 86468 4-fluoro-2,3,7,11b-tetrahydro-1H-pyrido[3,4,5-k]acridin-8,9-diol D(2) dopamine receptor Rattus norvegicus 160 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340609 136352517 ZINC87723409 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187616 Oc1ccc2[C@@H]3CNCc4c(F)ccc(Cc2c1O)c34 InChI=1S/C16H14FNO2/c17-13-3-1-8-5-10-9(2-4-14(19)16(10)20)11-6-18-7-12(13)15(8)11/h1-4,11,18-20H,5-7H2/t11-/m0/s1 JXSUIOSNLYNZRX-NSHDSACASA-N 86459 4-fluorodinapsoline hydrobromide::CAS_0::NSC_0 D(2) dopamine receptor Rattus norvegicus 28 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340601 136352508 ZINC13479471 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187617 Oc1ccc2[C@@H]3CNCc4c(O)ccc(Cc2c1O)c34 InChI=1S/C16H15NO3/c18-13-3-1-8-5-10-9(2-4-14(19)16(10)20)11-6-17-7-12(13)15(8)11/h1-4,11,17-20H,5-7H2/t11-/m0/s1 BODQFERAMYJCGI-NSHDSACASA-N 86456 4-hydroxydinapsoline hydrobromide D(2) dopamine receptor Rattus norvegicus 15 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340598 136352505 ZINC13479467 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187620 Oc1ccc2C3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2 ZQTSNGJHMUKLOM-UHFFFAOYSA-N 50117182 2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL120995::Dinapsoline, (+/-) D(2) dopamine receptor Rattus norvegicus 56 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5249490 104010782 CHEMBL120995 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187622 Oc1ccc2[C@@H]3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2/t13-/m0/s1 ZQTSNGJHMUKLOM-ZDUSSCGKSA-N 50117181 (S)-2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL124561::Dinapsoline, (+/-)::Dinapsoline, (R)(+) D(2) dopamine receptor Rattus norvegicus 38 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816455 104010781 CHEMBL124561 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187623 Oc1ccc2[C@H]3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2/t13-/m1/s1 ZQTSNGJHMUKLOM-CYBMUJFWSA-N 50117183 2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL123642::Dinapsoline, (S)(-) D(2) dopamine receptor Rattus norvegicus 1500 PDSP Ki 10.1016/j.bmc.2003.11.015 10.7270/Q2FF3QX2 14759732 Sit, SY; Xie, K; Jacutin-Porte, S; Boy, KM; Seanz, J; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Verdoorn, T; Johnson, G; Nichols, DE; Mailman, RB Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10923047 104010783 CHEMBL123642 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183816 Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H QYDURWHTEIUTEI-UHFFFAOYSA-N 50129952 2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-8-yl)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one::8-[5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxy-phenyl]-5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one::Amentoflavone::CHEMBL63354::cid_5281600 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s00213-002-1073-7 10.7270/Q25D8QDD 12110997 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL Westfälische Wilhelms-Universitä Muenster, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281600 104021411 2631 CHEMBL63354 ZINC03984030 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183817 CC(C)C(=O)[C@]12C(=O)C(CC=C(C)C)C(=O)[C@@](CC=C(C)C)(C[C@H](CC=C(C)C)[C@@]1(C)CCC=C(C)C)C2=O InChI=1S/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-28H,12,16-17,19-21H2,1-11H3/t27-,28?,33+,34+,35+/m0/s1 GQRREYKSPJMLAW-CWRBZUMDSA-N 50242259 CHEMBL516641::HYPERFORIN D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s00213-002-1073-7 10.7270/Q25D8QDD 12110997 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL Westfälische Wilhelms-Universitä Muenster, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242259&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91935559 104099004 CHEMBL516641 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183818 Cc1cc(O)c2c3c1c1c(CO)cc(O)c4c1c1c5c(c(O)cc(O)c5c4=O)c4c(O)cc(O)c(c4c31)c2=O InChI=1S/C30H16O9/c1-7-2-9(32)19-23-15(7)16-8(6-31)3-10(33)20-24(16)28-26-18(12(35)5-14(37)22(26)30(20)39)17-11(34)4-13(36)21(29(19)38)25(17)27(23)28/h2-5,31-37H,6H2,1H3 YXBUQQDFTYOHQI-UHFFFAOYSA-N 50333880 CHEMBL1614664::Hypericin::Pseudohypericin D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s00213-002-1073-7 10.7270/Q25D8QDD 12110997 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL Westfälische Wilhelms-Universitä Muenster, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50333880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50333880&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281751 125083982 CHEMBL1614664 C10392 ZINC03917574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183819 OCC1OC(Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)C(O)C(O)C1O InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-25,27-30H,6H2 DPFYPHSPTUZJJT-UHFFFAOYSA-N 86036 CAS_5318390::CAS_97331::Hyperoside::Miquelianin::NSC_5318390::NSC_97331 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s00213-002-1073-7 10.7270/Q25D8QDD 12110997 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL Westfälische Wilhelms-Universitä Muenster, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86036&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5378597 136352136 ZINC05004613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183820 OCC1OC(O)C(Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)C(O)C1O InChI=1S/C21H20O12/c22-6-13-15(27)17(29)20(21(30)32-13)33-19-16(28)14-11(26)4-8(23)5-12(14)31-18(19)7-1-2-9(24)10(25)3-7/h1-5,13,15,17,20-25,27-30H,6H2 JDCKEYDYTNBCCS-UHFFFAOYSA-N 84979 Isoquercitrin D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s00213-002-1073-7 10.7270/Q25D8QDD 12110997 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL Westfälische Wilhelms-Universitä Muenster, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84979&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339948 136351079 ZINC86865007 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183821 OCC1OC(Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)C(O)C(O)C1O InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-25,27-30H,6H2 DPFYPHSPTUZJJT-UHFFFAOYSA-N 86036 CAS_5318390::CAS_97331::Hyperoside::Miquelianin::NSC_5318390::NSC_97331 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s00213-002-1073-7 10.7270/Q25D8QDD 12110997 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL Westfälische Wilhelms-Universitä Muenster, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86036&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5378597 136352136 ZINC05004613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183822 Cc1cc(O)c2c3c1c1c(CO)cc(O)c4c1c1c5c(c(O)cc(O)c5c4=O)c4c(O)cc(O)c(c4c31)c2=O InChI=1S/C30H16O9/c1-7-2-9(32)19-23-15(7)16-8(6-31)3-10(33)20-24(16)28-26-18(12(35)5-14(37)22(26)30(20)39)17-11(34)4-13(36)21(29(19)38)25(17)27(23)28/h2-5,31-37H,6H2,1H3 YXBUQQDFTYOHQI-UHFFFAOYSA-N 50333880 CHEMBL1614664::Hypericin::Pseudohypericin D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s00213-002-1073-7 10.7270/Q25D8QDD 12110997 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL Westfälische Wilhelms-Universitä Muenster, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50333880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50333880&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5281751 125083982 CHEMBL1614664 C10392 ZINC03917574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183823 Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H REFJWTPEDVJJIY-UHFFFAOYSA-N 7460 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one::2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate::CHEMBL50::Quercetin::Quercetin (10)::Quercetin (21)::Quercetin (Qur)::US11021454, Compound Quercetin::US9180183, Quercetin::med.21724, Compound 4 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s00213-002-1073-7 10.7270/Q25D8QDD 12110997 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL Westfälische Wilhelms-Universitä Muenster, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7460&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search QUE 3BPT,2HCK,3LJ0,4LMU,5FLI,5FLJ,3CF8,4DFU,4MRA,4WNJ,2O3P,2MS6,5AUW,3BXX,6M89,3LM5,1GP6,6AWS,6QCN,6QCD,7VUM,6B1D,2N6C,1E8W,2C9Z,5XG4,5A4V,2UXH,1H1I,2JJ2,6TTA,6IJD,3NVY 5280343 11108251 16243 CHEMBL50 DB04216 5346 C00389 ZINC03869685 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183824 C[C@@H]1O[C@@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O InChI=1S/C21H20O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-18,21-24,26-29H,1H3/t7-,15-,17+,18+,21-/m0/s1 XHIUPRGKXRAZCR-HQBVPOQASA-N 84978 Quercitrin::cid_5280459 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s00213-002-1073-7 10.7270/Q25D8QDD 12110997 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL Westfälische Wilhelms-Universitä Muenster, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84978&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5280459 136351078 17558 C02757 ZINC04175638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183825 C[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3c(O)c4c(cc(O)cc4=O)oc3-c3ccc(O)c(O)c3)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O InChI=1S/C27H30O16/c1-8-17(32)20(35)22(37)26(40-8)39-7-15-18(33)21(36)23(38)27(42-15)43-25-19(34)16-13(31)5-10(28)6-14(16)41-24(25)9-2-3-11(29)12(30)4-9/h2-6,8,15,17-18,20-23,26-30,32-38H,7H2,1H3/t8-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1 HRFGZDXDXWODFE-NVPNHPEKSA-N 50217942 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside::3-Rhamnoglucosylquercetin::3-Rutinosyl quercetin::CHEMBL226335::cid_5280805::rutin D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1007/s00213-002-1073-7 10.7270/Q25D8QDD 12110997 Butterweck, V; Nahrstedt, A; Evans, J; Hufeisen, S; Rauser, L; Savage, J; Popadak, B; Ernsberger, P; Roth, BL Westfälische Wilhelms-Universitä Muenster, http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50217942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50217942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search RUT 1RY8 5280805 104091802 28527 CHEMBL226335 C02757 ZINC04096846 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185213 Cc1ccc2CN[C@H]3CCc4cc(O)c(O)cc4[C@@H]3c2c1 InChI=1S/C18H19NO2/c1-10-2-3-12-9-19-15-5-4-11-7-16(20)17(21)8-14(11)18(15)13(12)6-10/h2-3,6-8,15,18-21H,4-5,9H2,1H3/t15-,18-/m0/s1 DUJBUFXUMONRHW-YJBOKZPZSA-N 86179 Dihydrexidine, 2-methyl D(2) dopamine receptor Rattus norvegicus 302 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340488 136352279 ZINC87723271 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185214 CCCN1Cc2c(C)cccc2[C@@H]2[C@@H]1CCc1cc(O)c(O)cc21 InChI=1S/C21H25NO2/c1-3-9-22-12-17-13(2)5-4-6-15(17)21-16-11-20(24)19(23)10-14(16)7-8-18(21)22/h4-6,10-11,18,21,23-24H,3,7-9,12H2,1-2H3/t18-,21-/m0/s1 IURHNFGBYOFFDB-RXVVDRJESA-N 86182 Dihydrexidine, 4-methyl-N-propyl D(2) dopamine receptor Rattus norvegicus 9 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340490 136352282 ZINC49180814 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185215 Oc1cc2CCC3NCc4ccccc4C3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2 BGOQGUHWXBGXJW-UHFFFAOYSA-N 50049047 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL101446::Dihydrexidine::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 58.1 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60759 103979425 CHEMBL101446 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185216 CCCN1Cc2ccccc2[C@@H]2[C@@H]1CCc1cc(O)c(O)cc21 InChI=1S/C20H23NO2/c1-2-9-21-12-14-5-3-4-6-15(14)20-16-11-19(23)18(22)10-13(16)7-8-17(20)21/h3-6,10-11,17,20,22-23H,2,7-9,12H2,1H3/t17-,20-/m0/s1 VNVHTKVGILYCGH-PXNSSMCTSA-N 86181 Dihydrexidine, N-propyl D(2) dopamine receptor Rattus norvegicus 25.7 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340489 136352281 ZINC87723273 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185217 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 0.74 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185218 Cc1cccc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc12 InChI=1S/C18H19NO2/c1-10-3-2-4-12-14(10)9-19-15-6-5-11-7-16(20)17(21)8-13(11)18(12)15/h2-4,7-8,15,18-21H,5-6,9H2,1H3/t15-,18-/m0/s1 LYRRSOZNQRVMQC-YJBOKZPZSA-N 86176 Dihydrexidine, 4-methyl D(2) dopamine receptor Rattus norvegicus 674 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86176&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340485 136352276 ZINC89464521 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185219 CCCN1Cc2c(C)cccc2[C@@H]2[C@@H]1CCc1cc(O)c(O)cc21 InChI=1S/C21H25NO2/c1-3-9-22-12-17-13(2)5-4-6-15(17)21-16-11-20(24)19(23)10-14(16)7-8-18(21)22/h4-6,10-11,18,21,23-24H,3,7-9,12H2,1-2H3/t18-,21-/m0/s1 IURHNFGBYOFFDB-RXVVDRJESA-N 86182 Dihydrexidine, 4-methyl-N-propyl D(2) dopamine receptor Rattus norvegicus 229 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340490 136352282 ZINC49180814 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185220 Oc1cc2CCC3NCc4ccccc4C3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2 BGOQGUHWXBGXJW-UHFFFAOYSA-N 50049047 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL101446::Dihydrexidine::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 180 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60759 103979425 CHEMBL101446 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185221 Oc1cc2CCC3NCc4ccccc4C3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2 BGOQGUHWXBGXJW-UHFFFAOYSA-N 50049047 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL101446::Dihydrexidine::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 1490 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60759 103979425 CHEMBL101446 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185222 CCCN1Cc2ccccc2[C@@H]2[C@@H]1CCc1cc(O)c(O)cc21 InChI=1S/C20H23NO2/c1-2-9-21-12-14-5-3-4-6-15(14)20-16-11-19(23)18(22)10-13(16)7-8-17(20)21/h3-6,10-11,17,20,22-23H,2,7-9,12H2,1H3/t17-,20-/m0/s1 VNVHTKVGILYCGH-PXNSSMCTSA-N 86181 Dihydrexidine, N-propyl D(2) dopamine receptor Rattus norvegicus 434 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340489 136352281 ZINC87723273 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185223 Oc1ccc2[C@@H]3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2/t13-/m0/s1 ZQTSNGJHMUKLOM-ZDUSSCGKSA-N 50117181 (S)-2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL124561::Dinapsoline, (+/-)::Dinapsoline, (R)(+) D(2) dopamine receptor Rattus norvegicus 53 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816455 104010781 CHEMBL124561 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185224 Cc1ccc2Cc3c(O)c(O)ccc3[C@@H]3CNCc1c23 InChI=1S/C17H17NO2/c1-9-2-3-10-6-12-11(4-5-15(19)17(12)20)14-8-18-7-13(9)16(10)14/h2-5,14,18-20H,6-8H2,1H3/t14-/m0/s1 SOZRZRILJRQXRJ-AWEZNQCLSA-N 86184 Dinapsoline,(+/-)-4-Methyl D(2) dopamine receptor Rattus norvegicus 36 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86184&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340492 136352284 ZINC13478205 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185225 Cc1ccc2Cc3c(O)c(O)ccc3[C@@H]3CN(CC=C)Cc1c23 InChI=1S/C20H21NO2/c1-3-8-21-10-16-12(2)4-5-13-9-15-14(17(11-21)19(13)16)6-7-18(22)20(15)23/h3-7,17,22-23H,1,8-11H2,2H3/t17-/m0/s1 XQEGLESCYZVFOV-KRWDZBQOSA-N 86177 Dinapsoline,(+/-)-4-Methyl-N-allyl D(2) dopamine receptor Rattus norvegicus 36 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340486 136352277 ZINC13478209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185226 CCCN1C[C@H]2c3ccc(O)c(O)c3Cc3ccc(C)c(C1)c23 InChI=1S/C20H23NO2/c1-3-8-21-10-16-12(2)4-5-13-9-15-14(17(11-21)19(13)16)6-7-18(22)20(15)23/h4-7,17,22-23H,3,8-11H2,1-2H3/t17-/m0/s1 WBHGBBBSTOWRHE-KRWDZBQOSA-N 86183 Dinapsoline,(+/-)-4-Methyl-N-propyl D(2) dopamine receptor Rattus norvegicus 23 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340491 136352283 ZINC13478213 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185227 Cc1ccc2CNC[C@H]3c4ccc(O)c(O)c4Cc1c23 InChI=1S/C17H17NO2/c1-9-2-3-10-7-18-8-14-11-4-5-15(19)17(20)13(11)6-12(9)16(10)14/h2-5,14,18-20H,6-8H2,1H3/t14-/m0/s1 TVOXNLCISKSFLL-AWEZNQCLSA-N 86186 Dinapsoline,(+/-)-6-Methyl D(2) dopamine receptor Rattus norvegicus 190 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86186&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340494 136352286 ZINC13478201 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185228 Oc1ccc2[C@@H]3CN(CC=C)Cc4cccc(Cc2c1O)c34 InChI=1S/C19H19NO2/c1-2-8-20-10-13-5-3-4-12-9-15-14(16(11-20)18(12)13)6-7-17(21)19(15)22/h2-7,16,21-22H,1,8-11H2/t16-/m0/s1 COYZPLPXUJOQSU-INIZCTEOSA-N 86185 Dinapsoline,(+/-)-N-allyl D(2) dopamine receptor Rattus norvegicus 81 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86185&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340493 136352285 ZINC13478194 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185229 CCCN1C[C@H]2c3ccc(O)c(O)c3Cc3cccc(C1)c23 InChI=1S/C19H21NO2/c1-2-8-20-10-13-5-3-4-12-9-15-14(16(11-20)18(12)13)6-7-17(21)19(15)22/h3-7,16,21-22H,2,8-11H2,1H3/t16-/m0/s1 VKSXADRMMBMNET-INIZCTEOSA-N 86178 (+/-)-2-propyldinapsoline hydrobromide::Dinapsoline,(+/-)-N-propyl D(2) dopamine receptor Rattus norvegicus 39 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86178&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340487 136352278 ZINC13478198 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185279 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185280 Oc1cc2CCC3NCc4ccccc4C3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2 BGOQGUHWXBGXJW-UHFFFAOYSA-N 50049047 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL101446::Dihydrexidine::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 24 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60759 103979425 CHEMBL101446 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185281 Oc1ccc2[C@@H]3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2/t13-/m0/s1 ZQTSNGJHMUKLOM-ZDUSSCGKSA-N 50117181 (S)-2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL124561::Dinapsoline, (+/-)::Dinapsoline, (R)(+) D(2) dopamine receptor Rattus norvegicus 25 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816455 104010781 CHEMBL124561 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185282 Cc1ccc2Cc3c(O)c(O)ccc3[C@@H]3CNCc1c23 InChI=1S/C17H17NO2/c1-9-2-3-10-6-12-11(4-5-15(19)17(12)20)14-8-18-7-13(9)16(10)14/h2-5,14,18-20H,6-8H2,1H3/t14-/m0/s1 SOZRZRILJRQXRJ-AWEZNQCLSA-N 86184 Dinapsoline,(+/-)-4-Methyl D(2) dopamine receptor Rattus norvegicus 19 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86184&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340492 136352284 ZINC13478205 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185283 Cc1ccc2Cc3c(O)c(O)ccc3[C@@H]3CN(CC=C)Cc1c23 InChI=1S/C20H21NO2/c1-3-8-21-10-16-12(2)4-5-13-9-15-14(17(11-21)19(13)16)6-7-18(22)20(15)23/h3-7,17,22-23H,1,8-11H2,2H3/t17-/m0/s1 XQEGLESCYZVFOV-KRWDZBQOSA-N 86177 Dinapsoline,(+/-)-4-Methyl-N-allyl D(2) dopamine receptor Rattus norvegicus 49 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340486 136352277 ZINC13478209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185284 CCCN1C[C@H]2c3ccc(O)c(O)c3Cc3ccc(C)c(C1)c23 InChI=1S/C20H23NO2/c1-3-8-21-10-16-12(2)4-5-13-9-15-14(17(11-21)19(13)16)6-7-18(22)20(15)23/h4-7,17,22-23H,3,8-11H2,1-2H3/t17-/m0/s1 WBHGBBBSTOWRHE-KRWDZBQOSA-N 86183 Dinapsoline,(+/-)-4-Methyl-N-propyl D(2) dopamine receptor Rattus norvegicus 21 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340491 136352283 ZINC13478213 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185285 Cc1ccc2CNC[C@H]3c4ccc(O)c(O)c4Cc1c23 InChI=1S/C17H17NO2/c1-9-2-3-10-7-18-8-14-11-4-5-15(19)17(20)13(11)6-12(9)16(10)14/h2-5,14,18-20H,6-8H2,1H3/t14-/m0/s1 TVOXNLCISKSFLL-AWEZNQCLSA-N 86186 Dinapsoline,(+/-)-6-Methyl D(2) dopamine receptor Rattus norvegicus 57 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86186&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340494 136352286 ZINC13478201 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185286 Oc1ccc2[C@@H]3CN(CC=C)Cc4cccc(Cc2c1O)c34 InChI=1S/C19H19NO2/c1-2-8-20-10-13-5-3-4-12-9-15-14(16(11-20)18(12)13)6-7-17(21)19(15)22/h2-7,16,21-22H,1,8-11H2/t16-/m0/s1 COYZPLPXUJOQSU-INIZCTEOSA-N 86185 Dinapsoline,(+/-)-N-allyl D(2) dopamine receptor Rattus norvegicus 110 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86185&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340493 136352285 ZINC13478194 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 185287 CCCN1C[C@H]2c3ccc(O)c(O)c3Cc3cccc(C1)c23 InChI=1S/C19H21NO2/c1-2-8-20-10-13-5-3-4-12-9-15-14(16(11-20)18(12)13)6-7-17(21)19(15)22/h3-7,16,21-22H,2,8-11H2,1H3/t16-/m0/s1 VKSXADRMMBMNET-INIZCTEOSA-N 86178 (+/-)-2-propyldinapsoline hydrobromide::Dinapsoline,(+/-)-N-propyl D(2) dopamine receptor Rattus norvegicus 60 PDSP Ki 10.1016/S0968-0896(02)00561-8 10.7270/Q2CV4G90 12628671 Qandil, AM; Lewis, MM; Jassen, A; Leonard, SK; Mailman, RB; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86178&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340487 136352278 ZINC13478198 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186478 CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 ZUXABONWMNSFBN-UHFFFAOYSA-N 22869 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene::CLOZARIL::Clozapine::Leponex::US10259786, Clozapine D(2) dopamine receptor Rattus norvegicus 7600 PDSP Ki 10.1016/s0024-3205(03)00272-8 10.7270/Q2KD1WHW 12757844 Patel, S; Krause, SM; Hamill, T; Chaudhary, A; Burns, DH; Gibson, RA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 49846683 38 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 184038 O=C1Nc2cccc3ccc(CCCCN4CCC(=CC4)c4ccccc4)c1c23 InChI=1S/C26H26N2O/c29-26-25-22(13-12-21-10-6-11-23(27-26)24(21)25)9-4-5-16-28-17-14-20(15-18-28)19-7-2-1-3-8-19/h1-3,6-8,10-14H,4-5,9,15-18H2,(H,27,29) XEPBAFXWHAJWLF-UHFFFAOYSA-N 86039 DR4004 D(2) dopamine receptor Rattus norvegicus 104.71 PDSP Ki 10.1016/S0960-894X(02)00485-7 10.7270/Q2NG4P6T 12182857 Kikuchi, C; Hiranuma, T; Koyama, M Meiji Seika Kaisha, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340439 136352139 ZINC87723189 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186778 Oc1cc2[C@@H](CN(CC=C)CCc2c(Br)c1O)c1ccccc1 InChI=1S/C19H20BrNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m0/s1 KKZGFVAZUKHFAC-INIZCTEOSA-N 50004919 (R)(+)-BrAPB::CHEMBL286424::S-(-)-6-Br-APD3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus 209 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004919&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603729 103918466 CHEMBL286424 ZINC02530682 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186779 CN1CCc2c(Cl)c(O)c(O)cc2[C@H](C1)c1cccc(C)c1 InChI=1S/C18H20ClNO2/c1-11-4-3-5-12(8-11)15-10-20(2)7-6-13-14(15)9-16(21)18(22)17(13)19/h3-5,8-9,15,21-22H,6-7,10H2,1-2H3/t15-/m1/s1 JXMYTVOBSFOHAF-OAHLLOKOSA-N 86271 MCL-201 D(2) dopamine receptor Rattus norvegicus 2136 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86271&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SK9 7JVP 9995976 136352371 64001 ZINC03996039 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186780 CN1CCc2c(Cl)c(O)c(O)cc2[C@@H](C1)c1cccc(C)c1 InChI=1S/C18H20ClNO2/c1-11-4-3-5-12(8-11)15-10-20(2)7-6-13-14(15)9-16(21)18(22)17(13)19/h3-5,8-9,15,21-22H,6-7,10H2,1-2H3/t15-/m0/s1 JXMYTVOBSFOHAF-HNNXBMFYSA-N 86278 MCL-202 D(2) dopamine receptor Rattus norvegicus 515 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GBU 7CRH 6604003 136352378 64001 ZINC02511851 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186781 CN1CCc2c(Br)c(O)c(O)cc2[C@@H](C1)c1cccc(C)c1 InChI=1S/C18H20BrNO2/c1-11-4-3-5-12(8-11)15-10-20(2)7-6-13-14(15)9-16(21)18(22)17(13)19/h3-5,8-9,15,21-22H,6-7,10H2,1-2H3/t15-/m0/s1 KAWHMWCFXIXOBJ-HNNXBMFYSA-N 86275 MCL-203 D(2) dopamine receptor Rattus norvegicus 440 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86275&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340520 136352375 ZINC87723298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186782 Cc1cccc(c1)C1CN(CC=C)CCc2c(Br)c(O)c(O)cc12 InChI=1S/C20H22BrNO2/c1-3-8-22-9-7-15-16(11-18(23)20(24)19(15)21)17(12-22)14-6-4-5-13(2)10-14/h3-6,10-11,17,23-24H,1,7-9,12H2,2H3 TVRLDESCELGMME-UHFFFAOYSA-N 86266 MCL-204 D(2) dopamine receptor Rattus norvegicus 83.8 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86266&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340513 136352366 ZINC89464562 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186783 Cc1cccc(c1)C1CNCCc2c(Br)c(O)c(O)cc12 InChI=1S/C17H18BrNO2/c1-10-3-2-4-11(7-10)14-9-19-6-5-12-13(14)8-15(20)17(21)16(12)18/h2-4,7-8,14,19-21H,5-6,9H2,1H3 HGQXWXQQBNFBJT-UHFFFAOYSA-N 86270 MCL-205 D(2) dopamine receptor Rattus norvegicus 1072 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86270&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340516 136352370 ZINC89464577 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186784 CN1CCc2c(Cl)c(O)c(O)cc2C(C1)c1ccc(C)cc1 InChI=1S/C18H20ClNO2/c1-11-3-5-12(6-4-11)15-10-20(2)8-7-13-14(15)9-16(21)18(22)17(13)19/h3-6,9,15,21-22H,7-8,10H2,1-2H3 WGXCRBHBCVCFFQ-UHFFFAOYSA-N 86268 MCL-206 D(2) dopamine receptor Rattus norvegicus 362 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86268&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340515 136352368 ZINC89464570 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186785 CN1CCc2c(Cl)c(O)c(O)cc2C(C1)c1ccccc1C InChI=1S/C18H20ClNO2/c1-11-5-3-4-6-12(11)15-10-20(2)8-7-13-14(15)9-16(21)18(22)17(13)19/h3-6,9,15,21-22H,7-8,10H2,1-2H3 SXTBQXMNBBGFOM-UHFFFAOYSA-N 86276 CAS_0::MCL-207::NSC_0 D(2) dopamine receptor Rattus norvegicus 226 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86276&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340521 136352376 ZINC89464590 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186786 Cc1cccc(c1)C1CNCCc2c(Cl)c(O)c(O)cc12 InChI=1S/C17H18ClNO2/c1-10-3-2-4-11(7-10)14-9-19-6-5-12-13(14)8-15(20)17(21)16(12)18/h2-4,7-8,14,19-21H,5-6,9H2,1H3 QCRYFTXYPJTHHB-UHFFFAOYSA-N 86269 MCL-209 D(2) dopamine receptor Rattus norvegicus 5000 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86269&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357641 136352369 ZINC27187244 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186787 Cc1cccc(c1)C1CN(CC=C)CCc2c(Cl)c(O)c(O)cc12 InChI=1S/C20H22ClNO2/c1-3-8-22-9-7-15-16(11-18(23)20(24)19(15)21)17(12-22)14-6-4-5-13(2)10-14/h3-6,10-11,17,23-24H,1,7-9,12H2,2H3 HLNOXCRCYMOMLA-UHFFFAOYSA-N 86277 MCL-210 D(2) dopamine receptor Rattus norvegicus 119 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020353 136352377 64004 ZINC07992840 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186788 CN1CCc2c(cc(O)c(O)c2Br)[C@@H](C1)c1cccc(c1)C(F)(F)F InChI=1S/C18H17BrF3NO2/c1-23-6-5-12-13(8-15(24)17(25)16(12)19)14(9-23)10-3-2-4-11(7-10)18(20,21)22/h2-4,7-8,14,24-25H,5-6,9H2,1H3/t14-/m0/s1 FTKZFGGKMRGKQD-AWEZNQCLSA-N 86273 MCL-211 D(2) dopamine receptor Rattus norvegicus 1048 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340518 136352373 ZINC87723295 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186789 CN1CCc2c(Br)c(O)c(O)cc2C(C1)c1ccc(C)cc1 InChI=1S/C18H20BrNO2/c1-11-3-5-12(6-4-11)15-10-20(2)8-7-13-14(15)9-16(21)18(22)17(13)19/h3-6,9,15,21-22H,7-8,10H2,1-2H3 LBIPTTYQIBCFPG-UHFFFAOYSA-N 86264 MCL-212 D(2) dopamine receptor Rattus norvegicus 1031 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86264&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340511 136352364 ZINC89464558 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186790 Cc1ccc(cc1)C1CN(CC=C)CCc2c(Br)c(O)c(O)cc12 InChI=1S/C20H22BrNO2/c1-3-9-22-10-8-15-16(11-18(23)20(24)19(15)21)17(12-22)14-6-4-13(2)5-7-14/h3-7,11,17,23-24H,1,8-10,12H2,2H3 MOEBYVAWAFLVIS-UHFFFAOYSA-N 86281 MCL-213 D(2) dopamine receptor Rattus norvegicus 1705 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340524 136352381 ZINC87723307 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186791 CN1CCc2c(Br)c(O)c(O)cc2C(C1)c1ccccc1C InChI=1S/C18H20BrNO2/c1-11-5-3-4-6-12(11)15-10-20(2)8-7-13-14(15)9-16(21)18(22)17(13)19/h3-6,9,15,21-22H,7-8,10H2,1-2H3 ZKZLBHXLUDHZTB-UHFFFAOYSA-N 86267 MCL-214 D(2) dopamine receptor Rattus norvegicus 409 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86267&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340514 136352367 ZINC87723292 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186792 Cc1ccccc1C1CN(CC=C)CCc2c(Br)c(O)c(O)cc12 InChI=1S/C20H22BrNO2/c1-3-9-22-10-8-15-16(11-18(23)20(24)19(15)21)17(12-22)14-7-5-4-6-13(14)2/h3-7,11,17,23-24H,1,8-10,12H2,2H3 LKNDWNGHBUERDE-UHFFFAOYSA-N 86265 MCL-215 D(2) dopamine receptor Rattus norvegicus 239 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86265&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340512 136352365 ZINC87723288 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186793 Cc1ccccc1C1CNCCc2c(Br)c(O)c(O)cc12 InChI=1S/C17H18BrNO2/c1-10-4-2-3-5-11(10)14-9-19-7-6-12-13(14)8-15(20)17(21)16(12)18/h2-5,8,14,19-21H,6-7,9H2,1H3 ASXMASABHPVLSJ-UHFFFAOYSA-N 86280 MCL-216 D(2) dopamine receptor Rattus norvegicus 19.5 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340523 136352380 ZINC89464597 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186794 Oc1cc2C(CN(CC=C)CCc2c(Br)c1O)c1ccccc1C(F)(F)F InChI=1S/C20H19BrF3NO2/c1-2-8-25-9-7-13-14(10-17(26)19(27)18(13)21)15(11-25)12-5-3-4-6-16(12)20(22,23)24/h2-6,10,15,26-27H,1,7-9,11H2 PHGKHKLVMARJOV-UHFFFAOYSA-N 86272 MCL-217 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86272&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340517 136352372 ZINC89464582 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186795 Oc1cc2[C@@H](CNCCc2c(Br)c1O)c1cccc(c1)C(F)(F)F InChI=1S/C17H15BrF3NO2/c18-15-11-4-5-22-8-13(12(11)7-14(23)16(15)24)9-2-1-3-10(6-9)17(19,20)21/h1-3,6-7,13,22-24H,4-5,8H2/t13-/m0/s1 JXTPLVZCJWMJQJ-ZDUSSCGKSA-N 86274 MCL-218 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86274&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340519 136352374 ZINC89464585 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186796 CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3 GOTMKOSCLKVOGG-UHFFFAOYSA-N 86180 CAS_87075-17-0::NSC_5018::SCH 23390::SCH23390::US9359372, SCH23390 D(2) dopamine receptor Rattus norvegicus 1210 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86180&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5018 136352280 73297 ZINC02017840 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186797 Oc1cc2CCNCC(c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2 JUDKOGFHZYMDMF-UHFFFAOYSA-N 50004923 (+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1242 103918470 CHEMBL505308CHEMBL286080CHEMBL542700 935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186798 Oc1cc2CCN(CC=C)CC(c3ccccc3)c2cc1O InChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2 QBUVZVXIRYFENV-UHFFFAOYSA-N 50004918 (+/-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride::CHEMBL288090::CHEMBL552611::SKF 77434 D(2) dopamine receptor Rattus norvegicus 1000 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1241 103918465 63988 CHEMBL552611CHEMBL288090 ZINC03870332 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186799 Oc1cc2C(CNCCc2c(Cl)c1O)c1ccccc1 InChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2 GHWJEDJMOVUXEC-UHFFFAOYSA-N 86282 6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide::CAS_1218::CHEMBL553503::NSC_1218::SKF 81297::cid_11957706 D(2) dopamine receptor Rattus norvegicus 1272 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SK0 7LJC,7JV5 1218 136352382 CHEMBL553503 938 ZINC03783980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186800 Oc1cc2C(CN(CC=C)CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2 HJWHHQIVUHOBQN-UHFFFAOYSA-N 50004917 3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide(Cl-APB)::CHEMBL35354::CHEMBL544115::RS(+/-)-6-Cl-APB3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SKF 82958 D(2) dopamine receptor Rattus norvegicus 264 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1225 103918464 CHEMBL35354CHEMBL544115 ZINC03870318 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 186801 CN1CCc2c(Cl)c(O)c(O)cc2C(C1)c1cccc(C)c1 InChI=1S/C18H20ClNO2/c1-11-4-3-5-12(8-11)15-10-20(2)7-6-13-14(15)9-16(21)18(22)17(13)19/h3-5,8-9,15,21-22H,6-7,10H2,1-2H3 JXMYTVOBSFOHAF-UHFFFAOYSA-N 50274531 6-Chloro-3-methyl-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide::6-chloro-3-methyl-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide::CHEMBL520992::CHEMBL574558::SKF-83959 D(2) dopamine receptor Rattus norvegicus 920 PDSP Ki 10.1016/s0014-2999(03)02008-9 10.7270/Q2DN43MQ 12921854 Neumeyer, JL; Kula, NS; Bergman, J; Baldessarini, RJ Harvard University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SK9 7JVP 133538 104118280 63996 CHEMBL574558CHEMBL520992 ZINC03996039 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183411 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 0.72 PDSP Ki 10.1124/jpet.301.3.1166 10.7270/Q2V69H4V 12023552 Mottola, DM; Kilts, JD; Lewis, MM; Connery, HS; Walker, QD; Jones, SR; Booth, RG; Hyslop, DK; Piercey, M; Wightman, RM; Lawler, CP; Nichols, DE; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183412 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 1.2 PDSP Ki 10.1124/jpet.301.3.1166 10.7270/Q2V69H4V 12023552 Mottola, DM; Kilts, JD; Lewis, MM; Connery, HS; Walker, QD; Jones, SR; Booth, RG; Hyslop, DK; Piercey, M; Wightman, RM; Lawler, CP; Nichols, DE; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183413 Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17+/m1/s1 BGOQGUHWXBGXJW-PBHICJAKSA-N 50010685 (+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine::(6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL43345::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 14 PDSP Ki 10.1124/jpet.301.3.1166 10.7270/Q2V69H4V 12023552 Mottola, DM; Kilts, JD; Lewis, MM; Connery, HS; Walker, QD; Jones, SR; Booth, RG; Hyslop, DK; Piercey, M; Wightman, RM; Lawler, CP; Nichols, DE; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010685&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14708665 103923431 CHEMBL43345 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183414 Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17+/m1/s1 BGOQGUHWXBGXJW-PBHICJAKSA-N 50010685 (+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine::(6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL43345::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 50 PDSP Ki 10.1124/jpet.301.3.1166 10.7270/Q2V69H4V 12023552 Mottola, DM; Kilts, JD; Lewis, MM; Connery, HS; Walker, QD; Jones, SR; Booth, RG; Hyslop, DK; Piercey, M; Wightman, RM; Lawler, CP; Nichols, DE; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010685&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14708665 103923431 CHEMBL43345 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183415 CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 InChI=1S/C20H23NO2/c1-2-9-21-12-14-5-3-4-6-15(14)20-16-11-19(23)18(22)10-13(16)7-8-17(20)21/h3-6,10-11,17,20,22-23H,2,7-9,12H2,1H3/t17-,20-/m1/s1 VNVHTKVGILYCGH-YLJYHZDGSA-N 50010684 (6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL299161::N-n-propyldihydrexidine, N-Pr-DHX D(2) dopamine receptor Rattus norvegicus 6.5 PDSP Ki 10.1124/jpet.301.3.1166 10.7270/Q2V69H4V 12023552 Mottola, DM; Kilts, JD; Lewis, MM; Connery, HS; Walker, QD; Jones, SR; Booth, RG; Hyslop, DK; Piercey, M; Wightman, RM; Lawler, CP; Nichols, DE; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9904738 103923430 CHEMBL299161 ZINC13478187 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183416 CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 InChI=1S/C20H23NO2/c1-2-9-21-12-14-5-3-4-6-15(14)20-16-11-19(23)18(22)10-13(16)7-8-17(20)21/h3-6,10-11,17,20,22-23H,2,7-9,12H2,1H3/t17-,20-/m1/s1 VNVHTKVGILYCGH-YLJYHZDGSA-N 50010684 (6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL299161::N-n-propyldihydrexidine, N-Pr-DHX D(2) dopamine receptor Rattus norvegicus 20 PDSP Ki 10.1124/jpet.301.3.1166 10.7270/Q2V69H4V 12023552 Mottola, DM; Kilts, JD; Lewis, MM; Connery, HS; Walker, QD; Jones, SR; Booth, RG; Hyslop, DK; Piercey, M; Wightman, RM; Lawler, CP; Nichols, DE; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9904738 103923430 CHEMBL299161 ZINC13478187 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183417 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 48 PDSP Ki 10.1124/jpet.301.3.1166 10.7270/Q2V69H4V 12023552 Mottola, DM; Kilts, JD; Lewis, MM; Connery, HS; Walker, QD; Jones, SR; Booth, RG; Hyslop, DK; Piercey, M; Wightman, RM; Lawler, CP; Nichols, DE; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 183418 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 5000 PDSP Ki 10.1124/jpet.301.3.1166 10.7270/Q2V69H4V 12023552 Mottola, DM; Kilts, JD; Lewis, MM; Connery, HS; Walker, QD; Jones, SR; Booth, RG; Hyslop, DK; Piercey, M; Wightman, RM; Lawler, CP; Nichols, DE; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 188387 Oc1cc2CCC3NCc4ccccc4C3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2 BGOQGUHWXBGXJW-UHFFFAOYSA-N 50049047 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL101446::Dihydrexidine::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 50 PDSP Ki 10.1111/j.1527-3458.2004.tb00024.x 10.7270/Q2Z89B0M 15492773 Salmi, P; Isacson, R; Kull, B Karolinska Institutet http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60759 103979425 CHEMBL101446 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 188897 ONC=Nc1ccc(N2CCOCC2)c(Cl)c1 InChI=1S/C11H14ClN3O2/c12-10-7-9(13-8-14-16)1-2-11(10)15-3-5-17-6-4-15/h1-2,7-8,16H,3-6H2,(H,13,14) ZTXADXBIGLLOFX-UHFFFAOYSA-N 86694 N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyformamidine::TS-011 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1124/jpet.105.083964 10.7270/Q2MW2FQQ 15831442 Miyata, N; Seki, T; Tanaka, Y; Omura, T; Taniguchi, K; Doi, M; Bandou, K; Kametani, S; Sato, M; Okuyama, S; Cambj-Sapunar, L; Harder, DR; Roman, RJ Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86694&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816527 136352743 ZINC06746071 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187661 CCCN(CCC)CCc1cccc2NC(=O)Cc12 InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19) UHSKFQJFRQCDBE-UHFFFAOYSA-N 50020680 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE D(2) dopamine receptor Rattus norvegicus 1148.15 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5095 103931441 8888 CHEMBL589 DB00268 7295 C07564 ZINC00002041 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187662 CCCC1CC2=C(OCC=N2)C2(NC(=O)CC(O)=O)C=CCCC12 InChI=1S/C18H24N2O4/c1-2-5-12-10-14-17(24-9-8-19-14)18(7-4-3-6-13(12)18)20-15(21)11-16(22)23/h4,7-8,12-13H,2-3,5-6,9-11H2,1H3,(H,20,21)(H,22,23) BSBXGNLUQCQTGK-UHFFFAOYSA-N 86474 (+-)-trans-3,4,4a,5,6,10b-hexahydro-9-carbamoyl- 4-propyl-2H-naphth[1,2-b]-1,4-oxazine::S31411 (+-) D(2) dopamine receptor Rattus norvegicus 724.44 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91899089 136352523 C01656 ZINC87723425 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187663 CCCN1CCO[C@H]2[C@H]1CCc1ccc(cc21)C(N)=O InChI=1S/C16H22N2O2/c1-2-7-18-8-9-20-15-13-10-12(16(17)19)4-3-11(13)5-6-14(15)18/h3-4,10,14-15H,2,5-9H2,1H3,(H2,17,19)/t14-,15-/m1/s1 XKTRZPQOQOCNJU-HUUCEWRRSA-N 86473 S32504 (+) D(2) dopamine receptor Rattus norvegicus 457.09 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15389743 136352522 ZINC40819117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 187664 CCCC1CC2=C(OCC=N2)[C@]2(NC(=O)CC(O)=O)C=CCCC12 InChI=1S/C18H24N2O4/c1-2-5-12-10-14-17(24-9-8-19-14)18(7-4-3-6-13(12)18)20-15(21)11-16(22)23/h4,7-8,12-13H,2-3,5-6,9-11H2,1H3,(H,20,21)(H,22,23)/t12?,13?,18-/m0/s1 BSBXGNLUQCQTGK-KJBLDROHSA-N 86472 (-)-trans-3,4,4a,5,6,10b-hexahydro-9-carbamoyl- 4-propyl-2H-naphth[1,2-b]-1,4-oxazine::S32601 (-) D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1124/jpet.103.062398 10.7270/Q29S1PM2 14978194 Millan, MJ; Cussac, D; Gobert, A; Lejeune, F; Rivet, JM; Mannoury La Cour, C; Newman-Tancredi, A; Peglion, JL Institut de Recherches Servier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91899088 136352521 C01656 ZINC87723419 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 189003 COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2[N+]([O-])=O)CC1 InChI=1S/C26H34N4O4/c1-34-25-14-8-7-13-24(25)28-18-15-27(16-19-28)17-20-29(26(31)21-9-3-2-4-10-21)22-11-5-6-12-23(22)30(32)33/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3 HVMKWKIPLGPYAR-UHFFFAOYSA-N 85833 N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]- ethyl]-N-(2-nitrophenyl)cyclohexanecarboxamide::Rec 15/3079 D(2) dopamine receptor Rattus norvegicus 870.96 PDSP Ki 10.1124/jpet.105.087809 10.7270/Q2VD6X2V 15951403 Corradetti, R; Mlinar, B; Falsini, C; Pugliese, AM; Cilia, A; Destefani, C; Testa, R Universit&aagrove; di Firenze http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85833&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9847377 136351933 ZINC65731062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 189004 COc1ccccc1N(CCN1CCN(CC1)c1ccccc1OC)C(=O)C1CCCCC1 InChI=1S/C27H37N3O3/c1-32-25-14-8-6-12-23(25)29-19-16-28(17-20-29)18-21-30(24-13-7-9-15-26(24)33-2)27(31)22-10-4-3-5-11-22/h6-9,12-15,22H,3-5,10-11,16-21H2,1-2H3 QQLBAAQRZXVWPZ-UHFFFAOYSA-N 86709 Rec 27/0074 D(2) dopamine receptor Rattus norvegicus 316.23 PDSP Ki 10.1124/jpet.105.087809 10.7270/Q2VD6X2V 15951403 Corradetti, R; Mlinar, B; Falsini, C; Pugliese, AM; Cilia, A; Destefani, C; Testa, R Universit&aagrove; di Firenze http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86709&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9868460 136352758 ZINC13981002 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 189005 COc1ccc(Br)c(c1)N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2OC(F)(F)F)CC1 InChI=1S/C27H33BrF3N3O3/c1-36-21-11-12-22(28)24(19-21)33-16-13-32(14-17-33)15-18-34(26(35)20-7-3-2-4-8-20)23-9-5-6-10-25(23)37-27(29,30)31/h5-6,9-12,19-20H,2-4,7-8,13-18H2,1H3 IRNNHEZQBOQPHZ-UHFFFAOYSA-N 86710 Rec 27/0224 D(2) dopamine receptor Rattus norvegicus 4786.30 PDSP Ki 10.1124/jpet.105.087809 10.7270/Q2VD6X2V 15951403 Corradetti, R; Mlinar, B; Falsini, C; Pugliese, AM; Cilia, A; Destefani, C; Testa, R Universit&aagrove; di Firenze http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86710&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57340712 136352759 ZINC89464940 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 189006 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.60 PDSP Ki 10.1124/jpet.105.087809 10.7270/Q2VD6X2V 15951403 Corradetti, R; Mlinar, B; Falsini, C; Pugliese, AM; Cilia, A; Destefani, C; Testa, R Universit&aagrove; di Firenze http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 189007 COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3 SBPRIAGPYFYCRT-UHFFFAOYSA-N 86708 CAS_146714-97-8::CHEMBL31354::CHEMBL514874::CHEMBL537403::NSC_104911::WAY 100,635 D(2) dopamine receptor Rattus norvegicus 346.74 PDSP Ki 10.1124/jpet.105.087809 10.7270/Q2VD6X2V 15951403 Corradetti, R; Mlinar, B; Falsini, C; Pugliese, AM; Cilia, A; Destefani, C; Testa, R Universit&aagrove; di Firenze http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86708&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5684 136352757 CHEMBL537403CHEMBL514874CHEMBL31354 ZINC52541473 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 189059 COc1cccc(C(O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC InChI=1S/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3 HXTGXYRHXAGCFP-UHFFFAOYSA-N 50232153 (1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol::(2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol::CHEMBL257283::MDL 100907::MDL-100907 D(2) dopamine receptor Rattus norvegicus >10000 PDSP Ki 10.1038/sj.npp.1300819 10.7270/Q2KW5DMS 15999145 Pehek, EA; Nocjar, C; Roth, BL; Byrd, TA; Mabrouk, OS Case Western Reserve University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50232153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50232153&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60858 104055427 CHEMBL257283 ZINC01851117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 188383 Oc1cc2CCC3NCc4ccccc4C3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2 BGOQGUHWXBGXJW-UHFFFAOYSA-N 50049047 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL101446::Dihydrexidine::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 660 PDSP Ki 10.1111/j.1527-3458.2004.tb00024.x 10.7270/Q2Z89B0M 15492773 Salmi, P; Isacson, R; Kull, B Karolinska Institutet http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60759 103979425 CHEMBL101446 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 188384 Oc1cc2CCC3NCc4ccccc4C3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2 BGOQGUHWXBGXJW-UHFFFAOYSA-N 50049047 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL101446::Dihydrexidine::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 122 PDSP Ki 10.1111/j.1527-3458.2004.tb00024.x 10.7270/Q2Z89B0M 15492773 Salmi, P; Isacson, R; Kull, B Karolinska Institutet http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60759 103979425 CHEMBL101446 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 188385 Oc1cc2CCC3NCc4ccccc4C3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2 BGOQGUHWXBGXJW-UHFFFAOYSA-N 50049047 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL101446::Dihydrexidine::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 43.2 PDSP Ki 10.1111/j.1527-3458.2004.tb00024.x 10.7270/Q2Z89B0M 15492773 Salmi, P; Isacson, R; Kull, B Karolinska Institutet http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60759 103979425 CHEMBL101446 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 188386 Oc1cc2CCC3NCc4ccccc4C3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2 BGOQGUHWXBGXJW-UHFFFAOYSA-N 50049047 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL101446::Dihydrexidine::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus 43.8 PDSP Ki 10.1111/j.1527-3458.2004.tb00024.x 10.7270/Q2Z89B0M 15492773 Salmi, P; Isacson, R; Kull, B Karolinska Institutet http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60759 103979425 CHEMBL101446 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 261438 CNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CC2)NC(C)=O)CC1 InChI=1S/C19H30Cl2N6O/c1-13(28)23-15-5-3-14(4-6-15)7-8-26-9-11-27(12-10-26)18-16(20)17(21)24-19(22-2)25-18/h14-15H,3-12H2,1-2H3,(H,23,28)(H,22,24,25) URZKYHFMOZUGKN-UHFFFAOYSA-N 129716 US8802672, 1 D(2) dopamine receptor Rattus norvegicus 35 US Patent 10.7270/Q2FF3R1T aid1800622 US8802672 Szalai, GB; Csongor, EA; Domany, G; Gyertyan, I; Kiss, B; Laszy, J; Saghy, K; Schmidt, E; Farkas, S; Komlodi, Z Richter Gedeon Nyrt. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=129716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=129716&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25014898 225156057 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 261439 CNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CC2)NC(N)=O)CC1 InChI=1S/C18H29Cl2N7O/c1-22-18-24-15(20)14(19)16(25-18)27-10-8-26(9-11-27)7-6-12-2-4-13(5-3-12)23-17(21)28/h12-13H,2-11H2,1H3,(H3,21,23,28)(H,22,24,25) SEBCYHBUMNSZTL-UHFFFAOYSA-N 129717 US8802672, 2 D(2) dopamine receptor Rattus norvegicus 35 US Patent 10.7270/Q2FF3R1T aid1800622 US8802672 Szalai, GB; Csongor, EA; Domany, G; Gyertyan, I; Kiss, B; Laszy, J; Saghy, K; Schmidt, E; Farkas, S; Komlodi, Z Richter Gedeon Nyrt. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=129717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=129717&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25052016 225156058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 261440 CCNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CC2)NC(C)=O)CC1 InChI=1S/C20H32Cl2N6O/c1-3-23-20-25-18(22)17(21)19(26-20)28-12-10-27(11-13-28)9-8-15-4-6-16(7-5-15)24-14(2)29/h15-16H,3-13H2,1-2H3,(H,24,29)(H,23,25,26) NTEASVXKHYIMOF-UHFFFAOYSA-N 129718 US8802672, 6 D(2) dopamine receptor Rattus norvegicus 35 US Patent 10.7270/Q2FF3R1T aid1800622 US8802672 Szalai, GB; Csongor, EA; Domany, G; Gyertyan, I; Kiss, B; Laszy, J; Saghy, K; Schmidt, E; Farkas, S; Komlodi, Z Richter Gedeon Nyrt. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=129718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=129718&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25052020 225156059 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 261441 CNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CC2)NC(=O)N2CCOCC2)CC1 InChI=1S/C22H35Cl2N7O2/c1-25-21-27-19(24)18(23)20(28-21)30-10-8-29(9-11-30)7-6-16-2-4-17(5-3-16)26-22(32)31-12-14-33-15-13-31/h16-17H,2-15H2,1H3,(H,26,32)(H,25,27,28) AXVHZOULLRVZMO-UHFFFAOYSA-N 129719 US8802672, 7 D(2) dopamine receptor Rattus norvegicus 10 US Patent 10.7270/Q2FF3R1T aid1800622 US8802672 Szalai, GB; Csongor, EA; Domany, G; Gyertyan, I; Kiss, B; Laszy, J; Saghy, K; Schmidt, E; Farkas, S; Komlodi, Z Richter Gedeon Nyrt. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=129719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=129719&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25052021 225156060 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 261442 CCNC(=O)NC1CCC(CCN2CCN(CC2)c2nc(NC)nc(Cl)c2Cl)CC1 InChI=1S/C20H33Cl2N7O/c1-3-24-20(30)25-15-6-4-14(5-7-15)8-9-28-10-12-29(13-11-28)18-16(21)17(22)26-19(23-2)27-18/h14-15H,3-13H2,1-2H3,(H,23,26,27)(H2,24,25,30) WTAMPQCWYMBLRF-UHFFFAOYSA-N 129720 US8802672, 10 D(2) dopamine receptor Rattus norvegicus 10 US Patent 10.7270/Q2FF3R1T aid1800622 US8802672 Szalai, GB; Csongor, EA; Domany, G; Gyertyan, I; Kiss, B; Laszy, J; Saghy, K; Schmidt, E; Farkas, S; Komlodi, Z Richter Gedeon Nyrt. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=129720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=129720&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25052179 225156061 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 261443 CNc1nc(Cl)c(Cl)c(n1)N1CCN(CCC2CCC(CCC(N)=O)CC2)CC1 InChI=1S/C20H32Cl2N6O/c1-24-20-25-18(22)17(21)19(26-20)28-12-10-27(11-13-28)9-8-15-4-2-14(3-5-15)6-7-16(23)29/h14-15H,2-13H2,1H3,(H2,23,29)(H,24,25,26) SBHRHPDWHIVMGX-UHFFFAOYSA-N 129721 US8802672, 11 D(2) dopamine receptor Rattus norvegicus 10 US Patent 10.7270/Q2FF3R1T aid1800622 US8802672 Szalai, GB; Csongor, EA; Domany, G; Gyertyan, I; Kiss, B; Laszy, J; Saghy, K; Schmidt, E; Farkas, S; Komlodi, Z Richter Gedeon Nyrt. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=129721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=129721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86766850 225156062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 261444 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 96 US Patent 10.7270/Q2FF3R1T aid1800622 US8802672 Szalai, GB; Csongor, EA; Domany, G; Gyertyan, I; Kiss, B; Laszy, J; Saghy, K; Schmidt, E; Farkas, S; Komlodi, Z Richter Gedeon Nyrt. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 261445 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 13 US Patent 10.7270/Q2FF3R1T aid1800622 US8802672 Szalai, GB; Csongor, EA; Domany, G; Gyertyan, I; Kiss, B; Laszy, J; Saghy, K; Schmidt, E; Farkas, S; Komlodi, Z Richter Gedeon Nyrt. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347128 O=c1ccc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]1 InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-10,17-18H,1-2,11-16H2,(H,26,29) ZKIAIYBUSXZPLP-UHFFFAOYSA-N 194780 7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one::OPC 34712::Rexulti::US9206167, 1::USRE48059, Compound of Example 1::brexpiprazole D(2) dopamine receptor Rattus norvegicus 0.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194780&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73160133 318150541 DB09128 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347129 Cc1cc(=O)[nH]c2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc12 InChI=1S/C25H27N3O2S/c1-18-16-25(29)26-22-17-19(6-7-20(18)22)30-14-3-9-27-10-12-28(13-11-27)23-4-2-5-24-21(23)8-15-31-24/h2,4-8,15-17H,3,9-14H2,1H3,(H,26,29) KDRNGVINVOICBB-UHFFFAOYSA-N 194782 US9206167, 3::USRE48059, Compound of Example 3 D(2) dopamine receptor Rattus norvegicus 0.5 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 77162561 318150543 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347130 Cc1cc(=O)[nH]c2cc(OCCCCN3CCN(CC3)c3cccc4sccc34)ccc12 InChI=1S/C26H29N3O2S/c1-19-17-26(30)27-23-18-20(7-8-21(19)23)31-15-3-2-10-28-11-13-29(14-12-28)24-5-4-6-25-22(24)9-16-32-25/h4-9,16-18H,2-3,10-15H2,1H3,(H,27,30) UDHIXAYFUPCVNQ-UHFFFAOYSA-N 194783 US9206167, 4::USRE48059, Compound of Example 4 D(2) dopamine receptor Rattus norvegicus 0.5 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194783&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 77162627 318150544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347131 Cc1cc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]c1=O InChI=1S/C25H27N3O2S/c1-18-16-19-6-7-20(17-22(19)26-25(18)29)30-14-3-9-27-10-12-28(13-11-27)23-4-2-5-24-21(23)8-15-31-24/h2,4-8,15-17H,3,9-14H2,1H3,(H,26,29) NHZKQPUHNXXGKW-UHFFFAOYSA-N 194784 US9206167, 5::USRE48059, Compound of Example 5 D(2) dopamine receptor Rattus norvegicus 0.6 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194784&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172714 318150545 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347132 Cc1cc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]c1=O InChI=1S/C26H29N3O2S/c1-19-17-20-7-8-21(18-23(20)27-26(19)30)31-15-3-2-10-28-11-13-29(14-12-28)24-5-4-6-25-22(24)9-16-32-25/h4-9,16-18H,2-3,10-15H2,1H3,(H,27,30) PHLDMSHQFGMHOE-UHFFFAOYSA-N 194785 US9206167, 6::USRE48059, Compound of Example 6 D(2) dopamine receptor Rattus norvegicus 0.8 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 74375865 318150546 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347133 O=c1ccc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]1 InChI=1S/C24H25N3O2S/c28-24-8-6-18-5-7-19(17-21(18)25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-20(22)9-16-30-23/h1,3-9,16-17H,2,10-15H2,(H,25,28) VDRZDRCYBDVYFF-UHFFFAOYSA-N 194786 US9206167, 7::USRE48059, Compound of Example 7 D(2) dopamine receptor Rattus norvegicus 0.5 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73160134 318150547 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347134 O=C1CCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C24H27N3O2S/c28-24-8-6-18-5-7-19(17-21(18)25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-20(22)9-16-30-23/h1,3-5,7,9,16-17H,2,6,8,10-15H2,(H,25,28) OESURDJKQAMNOQ-UHFFFAOYSA-N 194789 US9206167, 10::USRE48059, Compound of Example 10 D(2) dopamine receptor Rattus norvegicus 0.4 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194789&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978815 318150550 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347135 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C25H29N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-6,8,10,17-18H,1-2,7,9,11-16H2,(H,26,29) LAWOHKNPRBDADQ-UHFFFAOYSA-N 194790 US9206167, 11::US9206167, 12::USRE48059, Compound of Example 12 D(2) dopamine receptor Rattus norvegicus 0.1 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11857245 318150551 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347136 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C25H29N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-6,8,10,17-18H,1-2,7,9,11-16H2,(H,26,29) LAWOHKNPRBDADQ-UHFFFAOYSA-N 194790 US9206167, 11::US9206167, 12::USRE48059, Compound of Example 12 D(2) dopamine receptor Rattus norvegicus 0.1 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11857245 318150551 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347137 O=C1CCc2ccc(OC\C=C/CN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h1-6,8,10,17-18H,7,9,11-16H2,(H,26,29)/b2-1- PFDUTSYNBVBRFL-UPHRSURJSA-N 194792 US9206167, 13::USRE48059, Compound of Example 13 D(2) dopamine receptor Rattus norvegicus 2.4 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24968724 318150552 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347138 CC(CCOc1ccc2CCC(=O)Nc2c1)CN1CCN(CC1)c1cccc2sccc12 InChI=1S/C26H31N3O2S/c1-19(9-15-31-21-7-5-20-6-8-26(30)27-23(20)17-21)18-28-11-13-29(14-12-28)24-3-2-4-25-22(24)10-16-32-25/h2-5,7,10,16-17,19H,6,8-9,11-15,18H2,1H3,(H,27,30) MAKRXTXQAUBBSF-UHFFFAOYSA-N 194793 US9206167, 14::USRE48059, Compound of Example 14 D(2) dopamine receptor Rattus norvegicus 3.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194793&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24968725 318150553 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347139 O=C1CCc2ccc(OC\C=C\CN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h1-6,8,10,17-18H,7,9,11-16H2,(H,26,29)/b2-1+ PFDUTSYNBVBRFL-OWOJBTEDSA-N 194794 US9206167, 15::USRE48059, Compound of Example 15 D(2) dopamine receptor Rattus norvegicus 0.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194794&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24968726 318150554 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347140 CC1CC(=O)Nc2cc(OCCCCN3CCN(CC3)c3cccc4sccc34)ccc12 InChI=1S/C26H31N3O2S/c1-19-17-26(30)27-23-18-20(7-8-21(19)23)31-15-3-2-10-28-11-13-29(14-12-28)24-5-4-6-25-22(24)9-16-32-25/h4-9,16,18-19H,2-3,10-15,17H2,1H3,(H,27,30) FASXOXVOBCJFBS-UHFFFAOYSA-N 194795 US9206167, 16::USRE48059, Compound of Example 16 D(2) dopamine receptor Rattus norvegicus 0.7 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194795&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885300 318150555 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347141 O=C1CCc2ccc(OCCOCCN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C25H29N3O3S/c29-25-7-5-19-4-6-20(18-22(19)26-25)31-16-15-30-14-13-27-9-11-28(12-10-27)23-2-1-3-24-21(23)8-17-32-24/h1-4,6,8,17-18H,5,7,9-16H2,(H,26,29) MOISFIHQAJXBGP-UHFFFAOYSA-N 194796 US9206167, 17::USRE48059, Compound of Example 17 D(2) dopamine receptor Rattus norvegicus 2.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885287 318150556 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347142 CN1C(=O)CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc12 InChI=1S/C26H31N3O2S/c1-27-24-19-21(9-7-20(24)8-10-26(27)30)31-17-3-2-12-28-13-15-29(16-14-28)23-5-4-6-25-22(23)11-18-32-25/h4-7,9,11,18-19H,2-3,8,10,12-17H2,1H3 PUJLFURZMNJZQS-UHFFFAOYSA-N 194797 US9206167, 18::USRE48059, Compound of Example 18 D(2) dopamine receptor Rattus norvegicus 2.6 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978816 318150557 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347143 O=C1CCc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc2N1 InChI=1S/C24H27N3O2S/c28-24-8-5-18-17-19(6-7-21(18)25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-20(22)9-16-30-23/h1,3-4,6-7,9,16-17H,2,5,8,10-15H2,(H,25,28) SVNKBCHDVYMMAY-UHFFFAOYSA-N 194798 US9206167, 19::USRE48059, Compound of Example 19 D(2) dopamine receptor Rattus norvegicus 1.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194798&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978817 318150558 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347144 O=C1CCc2cc(OCCCCN3CCN(CC3)c3cccc4sccc34)ccc2N1 InChI=1S/C25H29N3O2S/c29-25-9-6-19-18-20(7-8-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-5,7-8,10,17-18H,1-2,6,9,11-16H2,(H,26,29) VPHRLRRZHMPEBH-UHFFFAOYSA-N 194799 US9206167, 20::USRE48059, Compound of Example 20 D(2) dopamine receptor Rattus norvegicus 1.5 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66886115 318150559 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347145 O=C1CCc2ccccc2N1CCCCCN1CCN(CC1)c1cccc2sccc12 InChI=1S/C26H31N3OS/c30-26-12-11-21-7-2-3-8-23(21)29(26)15-5-1-4-14-27-16-18-28(19-17-27)24-9-6-10-25-22(24)13-20-31-25/h2-3,6-10,13,20H,1,4-5,11-12,14-19H2 UYLAEYTXDWXVNM-UHFFFAOYSA-N 194801 US9206167, 22::USRE48059, Compound of Example 22 D(2) dopamine receptor Rattus norvegicus 4 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66884093 318150561 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347146 O=C1N(CCCCN2CCN(CC2)c2cccc3sccc23)CCc2ccccc12 InChI=1S/C25H29N3OS/c29-25-21-7-2-1-6-20(21)10-14-28(25)13-4-3-12-26-15-17-27(18-16-26)23-8-5-9-24-22(23)11-19-30-24/h1-2,5-9,11,19H,3-4,10,12-18H2 QZMDTGLDHUBNDE-UHFFFAOYSA-N 194802 US9206167, 23::USRE48059, Compound of Example 23 D(2) dopamine receptor Rattus norvegicus 0.7 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885601 318150562 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347147 O=C1N(CCCCCN2CCN(CC2)c2cccc3sccc23)CCc2ccccc12 InChI=1S/C26H31N3OS/c30-26-22-8-3-2-7-21(22)11-15-29(26)14-5-1-4-13-27-16-18-28(19-17-27)24-9-6-10-25-23(24)12-20-31-25/h2-3,6-10,12,20H,1,4-5,11,13-19H2 GNAVDNPHMGSLMD-UHFFFAOYSA-N 194803 US9206167, 24::USRE48059, Compound of Example 24 D(2) dopamine receptor Rattus norvegicus 5 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66884834 318150563 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347148 CN1CCc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc2C1=O InChI=1S/C25H29N3O2S/c1-26-11-8-19-18-20(6-7-21(19)25(26)29)30-16-3-10-27-12-14-28(15-13-27)23-4-2-5-24-22(23)9-17-31-24/h2,4-7,9,17-18H,3,8,10-16H2,1H3 XFIBBCPMZFVKIB-UHFFFAOYSA-N 194805 US9206167, 26::USRE48059, Compound of Example 26 D(2) dopamine receptor Rattus norvegicus 3.5 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885771 318150565 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347149 CCN1CCc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc2C1=O InChI=1S/C26H31N3O2S/c1-2-28-12-9-20-19-21(7-8-22(20)26(28)30)31-17-4-11-27-13-15-29(16-14-27)24-5-3-6-25-23(24)10-18-32-25/h3,5-8,10,18-19H,2,4,9,11-17H2,1H3 HGQRBZGJYMFYOO-UHFFFAOYSA-N 194806 US9206167, 27::USRE48059, Compound of Example 27 D(2) dopamine receptor Rattus norvegicus 4.9 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885975 318150566 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347150 O=C1NCCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc12 InChI=1S/C24H27N3O2S/c28-24-21-17-19(6-5-18(21)7-9-25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-20(22)8-16-30-23/h1,3-6,8,16-17H,2,7,9-15H2,(H,25,28) ZCVYWZZKFYUXJC-UHFFFAOYSA-N 194807 US10501452, Compound C::US9206167, 28::USRE48059, Compound of Example 28 D(2) dopamine receptor Rattus norvegicus 1.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978818 318150567 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347151 CN1CCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O InChI=1S/C25H29N3O2S/c1-26-11-8-19-6-7-20(18-22(19)25(26)29)30-16-3-10-27-12-14-28(15-13-27)23-4-2-5-24-21(23)9-17-31-24/h2,4-7,9,17-18H,3,8,10-16H2,1H3 RDOLSJCBVSDISX-UHFFFAOYSA-N 194808 US10501452, Compound B::US9206167, 30::USRE48059, Compound of Example 30 D(2) dopamine receptor Rattus norvegicus 0.7 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978936 318150568 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347152 CCN1CCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O InChI=1S/C26H31N3O2S/c1-2-28-12-9-20-7-8-21(19-23(20)26(28)30)31-17-4-11-27-13-15-29(16-14-27)24-5-3-6-25-22(24)10-18-32-25/h3,5-8,10,18-19H,2,4,9,11-17H2,1H3 HOTLVLKNIWVDRD-UHFFFAOYSA-N 194809 US9206167, 31::USRE48059, Compound of Example 31 D(2) dopamine receptor Rattus norvegicus 1.4 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885795 318150569 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347153 CN1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O InChI=1S/C26H31N3O2S/c1-27-12-9-20-7-8-21(19-23(20)26(27)30)31-17-3-2-11-28-13-15-29(16-14-28)24-5-4-6-25-22(24)10-18-32-25/h4-8,10,18-19H,2-3,9,11-17H2,1H3 IIQHIUSOYHIMSR-UHFFFAOYSA-N 194810 US9206167, 32::USRE48059, Compound of Example 32 D(2) dopamine receptor Rattus norvegicus 1.5 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978937 318150570 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347154 O=C1NCCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc12 InChI=1S/C25H29N3O2S/c29-25-22-18-20(7-6-19(22)8-10-26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)9-17-31-24/h3-7,9,17-18H,1-2,8,10-16H2,(H,26,29) JJQVVHYUPXCLCP-UHFFFAOYSA-N 194811 US9206167, 33::USRE48059, Compound of Example 33 D(2) dopamine receptor Rattus norvegicus 1.1 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978938 318150571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347155 O=c1n(CCCCN2CCN(CC2)c2cccc3sccc23)ccc2ccccc12 InChI=1S/C25H27N3OS/c29-25-21-7-2-1-6-20(21)10-14-28(25)13-4-3-12-26-15-17-27(18-16-26)23-8-5-9-24-22(23)11-19-30-24/h1-2,5-11,14,19H,3-4,12-13,15-18H2 JYXRPFUZHOBUIE-UHFFFAOYSA-N 194812 US9206167, 34::USRE48059, Compound of Example 34 D(2) dopamine receptor Rattus norvegicus 1.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194812&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885503 318150572 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347156 O=c1[nH]ccc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc12 InChI=1S/C24H25N3O2S/c28-24-21-17-19(6-5-18(21)7-9-25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-20(22)8-16-30-23/h1,3-9,16-17H,2,10-15H2,(H,25,28) KBDPNEXGRBZDFM-UHFFFAOYSA-N 194813 US9206167, 35::USRE48059, Compound of Example 35 D(2) dopamine receptor Rattus norvegicus 1.6 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172715 318150573 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347157 Cn1ccc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2c1=O InChI=1S/C25H27N3O2S/c1-26-11-8-19-6-7-20(18-22(19)25(26)29)30-16-3-10-27-12-14-28(15-13-27)23-4-2-5-24-21(23)9-17-31-24/h2,4-9,11,17-18H,3,10,12-16H2,1H3 CVMRJJLVIWWJTQ-UHFFFAOYSA-N 194814 US9206167, 36::USRE48059, Compound of Example 36 D(2) dopamine receptor Rattus norvegicus 1 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978940 318150574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347158 CCn1ccc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2c1=O InChI=1S/C26H29N3O2S/c1-2-28-12-9-20-7-8-21(19-23(20)26(28)30)31-17-4-11-27-13-15-29(16-14-27)24-5-3-6-25-22(24)10-18-32-25/h3,5-10,12,18-19H,2,4,11,13-17H2,1H3 PDNXHLGRGCXECB-UHFFFAOYSA-N 194815 US9206167, 37::USRE48059, Compound of Example 37 D(2) dopamine receptor Rattus norvegicus 1.9 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885504 318150575 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347159 COc1ccc2ccn(CCCCN3CCN(CC3)c3cccc4sccc34)c(=O)c2c1 InChI=1S/C26H29N3O2S/c1-31-21-8-7-20-9-13-29(26(30)23(20)19-21)12-3-2-11-27-14-16-28(17-15-27)24-5-4-6-25-22(24)10-18-32-25/h4-10,13,18-19H,2-3,11-12,14-17H2,1H3 VNFXFHGUVVNZTJ-UHFFFAOYSA-N 194816 US9206167, 38::USRE48059, Compound of Example 38 D(2) dopamine receptor Rattus norvegicus 1.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66884823 318150576 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347160 Oc1ccc2ccn(CCCCN3CCN(CC3)c3cccc4sccc34)c(=O)c2c1 InChI=1S/C25H27N3O2S/c29-20-7-6-19-8-12-28(25(30)22(19)18-20)11-2-1-10-26-13-15-27(16-14-26)23-4-3-5-24-21(23)9-17-31-24/h3-9,12,17-18,29H,1-2,10-11,13-16H2 RHGQBJJYWPWFSG-UHFFFAOYSA-N 194817 US9206167, 39::USRE48059, Compound of Example 39 D(2) dopamine receptor Rattus norvegicus 1.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885761 318150577 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347161 O=c1[nH]ccc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc12 InChI=1S/C24H25N3O2S/c28-24-20-6-5-19(17-18(20)7-9-25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-21(22)8-16-30-23/h1,3-9,16-17H,2,10-15H2,(H,25,28) KFNYOATUSDCRLT-UHFFFAOYSA-N 194818 US9206167, 40::USRE48059, Compound of Example 40 D(2) dopamine receptor Rattus norvegicus 4.8 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 77162624 318150578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347162 Cn1ccc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc2c1=O InChI=1S/C25H27N3O2S/c1-26-11-8-19-18-20(6-7-21(19)25(26)29)30-16-3-10-27-12-14-28(15-13-27)23-4-2-5-24-22(23)9-17-31-24/h2,4-9,11,17-18H,3,10,12-16H2,1H3 FQLPASRHPPCIMN-UHFFFAOYSA-N 194819 US9206167, 41::USRE48059, Compound of Example 41 D(2) dopamine receptor Rattus norvegicus 1.9 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885615 318150579 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347163 CC1CN(CCCOc2ccc3CCC(=O)Nc3c2)CCN1c1cccc2sccc12 InChI=1S/C25H29N3O2S/c1-18-17-27(12-13-28(18)23-4-2-5-24-21(23)10-15-31-24)11-3-14-30-20-8-6-19-7-9-25(29)26-22(19)16-20/h2,4-6,8,10,15-16,18H,3,7,9,11-14,17H2,1H3,(H,26,29) QFULDVZQWPDVTC-UHFFFAOYSA-N 194754 US9206167, 64 D(2) dopamine receptor Rattus norvegicus 3.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194754&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172689 318150515 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347164 CC1CN(CCN1CCCCOc1ccc2CCC(=O)Nc2c1)c1cccc2sccc12 InChI=1S/C26H31N3O2S/c1-19-18-29(24-5-4-6-25-22(24)11-16-32-25)14-13-28(19)12-2-3-15-31-21-9-7-20-8-10-26(30)27-23(20)17-21/h4-7,9,11,16-17,19H,2-3,8,10,12-15,18H2,1H3,(H,27,30) OACWYMMALIJANL-UHFFFAOYSA-N 194755 US9206167, 68 D(2) dopamine receptor Rattus norvegicus 1 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172690 318150516 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347165 CC1CN(CCN1CCCCOc1ccc2ccc(=O)[nH]c2c1)c1cccc2sccc12 194756 US9206167, 69 D(2) dopamine receptor Rattus norvegicus 0.8 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194756&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172691 318150517 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347166 C(COc1cccc2cccnc12)CN1CCN(CC1)c1cccc2sccc12 InChI=1S/C24H25N3OS/c1-5-19-6-3-11-25-24(19)22(8-1)28-17-4-12-26-13-15-27(16-14-26)21-7-2-9-23-20(21)10-18-29-23/h1-3,5-11,18H,4,12-17H2 HPWPNAWXBNRTHL-UHFFFAOYSA-N 194757 US9206167, 73 D(2) dopamine receptor Rattus norvegicus 4 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194757&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172692 318150518 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347167 CC(=O)N1CCCc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc12 InChI=1S/C26H31N3O2S/c1-20(30)29-12-3-5-21-19-22(8-9-24(21)29)31-17-4-11-27-13-15-28(16-14-27)25-6-2-7-26-23(25)10-18-32-26/h2,6-10,18-19H,3-5,11-17H2,1H3 MMOJTMXHMRXIIU-UHFFFAOYSA-N 194758 US9206167, 79 D(2) dopamine receptor Rattus norvegicus 4.7 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194758&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172693 318150519 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347168 C(COc1ccc2CCNCc2c1)CN1CCN(CC1)c1cccc2sccc12 InChI=1S/C24H29N3OS/c1-3-23(22-8-16-29-24(22)4-1)27-13-11-26(12-14-27)10-2-15-28-21-6-5-19-7-9-25-18-20(19)17-21/h1,3-6,8,16-17,25H,2,7,9-15,18H2 FRUDQTZRVOVULE-UHFFFAOYSA-N 194759 US9206167, 80 D(2) dopamine receptor Rattus norvegicus 1.5 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194759&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66886030 318150520 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347169 CC(=O)N1CCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2C1 InChI=1S/C26H31N3O2S/c1-20(30)29-11-8-21-6-7-23(18-22(21)19-29)31-16-3-10-27-12-14-28(15-13-27)25-4-2-5-26-24(25)9-17-32-26/h2,4-7,9,17-18H,3,8,10-16,19H2,1H3 DNHQZUHOZJMFSD-UHFFFAOYSA-N 194760 US9206167, 81 D(2) dopamine receptor Rattus norvegicus 0.8 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194760&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172694 318150521 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347170 C(COc1ccc2cccnc2c1)CN1CCN(CC1)c1cccc2sccc12 InChI=1S/C24H25N3OS/c1-5-23(21-9-17-29-24(21)6-1)27-14-12-26(13-15-27)11-3-16-28-20-8-7-19-4-2-10-25-22(19)18-20/h1-2,4-10,17-18H,3,11-16H2 LPOWYKJTFOKPSK-UHFFFAOYSA-N 194762 US9206167, 84 D(2) dopamine receptor Rattus norvegicus 2.4 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194762&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172696 318150523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347171 C(CCN1CCN(CC1)c1cccc2sccc12)COc1ccc2cccnc2c1 InChI=1S/C25H27N3OS/c1(2-17-29-21-9-8-20-5-4-11-26-23(20)19-21)12-27-13-15-28(16-14-27)24-6-3-7-25-22(24)10-18-30-25/h3-11,18-19H,1-2,12-17H2 BXJAQPIJTACZJF-UHFFFAOYSA-N 194761 US9206167, 85 D(2) dopamine receptor Rattus norvegicus 2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194761&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172695 318150522 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347172 CC(=O)N1CCc2ccc(COCCCCN3CCN(CC3)c3cccc4sccc34)cc2C1 InChI=1S/C28H35N3O2S/c1-22(32)31-12-9-24-8-7-23(19-25(24)20-31)21-33-17-3-2-11-29-13-15-30(16-14-29)27-5-4-6-28-26(27)10-18-34-28/h4-8,10,18-19H,2-3,9,11-17,20-21H2,1H3 FZXUJLPYLIQVQU-UHFFFAOYSA-N 194764 US9206167, 90 D(2) dopamine receptor Rattus norvegicus 0.4 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172698 318150525 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347173 Fc1cc2CCNC(=O)c2cc1COCCCCN1CCN(CC1)c1cccc2sccc12 InChI=1S/C26H30FN3O2S/c27-23-17-19-6-8-28-26(31)22(19)16-20(23)18-32-14-2-1-9-29-10-12-30(13-11-29)24-4-3-5-25-21(24)7-15-33-25/h3-5,7,15-17H,1-2,6,8-14,18H2,(H,28,31) QMQQGNVMQBEIOF-UHFFFAOYSA-N 194765 US9206167, 91 D(2) dopamine receptor Rattus norvegicus 1.4 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194765&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172699 318150526 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347174 CN1CCc2cc(F)c(COCCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O InChI=1S/C27H32FN3O2S/c1-29-10-7-20-18-24(28)21(17-23(20)27(29)32)19-33-15-3-2-9-30-11-13-31(14-12-30)25-5-4-6-26-22(25)8-16-34-26/h4-6,8,16-18H,2-3,7,9-15,19H2,1H3 WAJUKWCONSQXQF-UHFFFAOYSA-N 194766 US9206167, 92 D(2) dopamine receptor Rattus norvegicus 1.7 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172700 318150527 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347175 Fc1cc(OCCCN2CCN(CC2)c2cccc3sccc23)cc2CCC(=O)Nc12 InChI=1S/C24H26FN3O2S/c25-20-16-18(15-17-5-6-23(29)26-24(17)20)30-13-2-8-27-9-11-28(12-10-27)21-3-1-4-22-19(21)7-14-31-22/h1,3-4,7,14-16H,2,5-6,8-13H2,(H,26,29) VGMMKAWLAFTFHD-UHFFFAOYSA-N 194767 US9206167, 116 D(2) dopamine receptor Rattus norvegicus 4.5 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194767&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172701 318150528 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347176 Cc1cccc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)c(=O)[nH]c12 InChI=1S/C25H27N3O2S/c1-18-5-2-6-19-17-22(25(29)26-24(18)19)30-15-4-10-27-11-13-28(14-12-27)21-7-3-8-23-20(21)9-16-31-23/h2-3,5-9,16-17H,4,10-15H2,1H3,(H,26,29) VVRUSUSURLOZQA-UHFFFAOYSA-N 194768 US9206167, 117 D(2) dopamine receptor Rattus norvegicus 4.7 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194768&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172702 318150529 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347177 Fc1cc(OCCCN2CCN(CC2)c2cccc3sccc23)cc2ccc(=O)[nH]c12 InChI=1S/C24H24FN3O2S/c25-20-16-18(15-17-5-6-23(29)26-24(17)20)30-13-2-8-27-9-11-28(12-10-27)21-3-1-4-22-19(21)7-14-31-22/h1,3-7,14-16H,2,8-13H2,(H,26,29) ZFZUJZBNGFMIEE-UHFFFAOYSA-N 194769 US9206167, 118 D(2) dopamine receptor Rattus norvegicus 3.5 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194769&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172703 318150530 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347178 O=C1CCc2c(N1)cccc2OCCCN1CCN(CC1)c1cccc2sccc12 InChI=1S/C24H27N3O2S/c28-24-9-8-18-20(25-24)4-1-6-22(18)29-16-3-11-26-12-14-27(15-13-26)21-5-2-7-23-19(21)10-17-30-23/h1-2,4-7,10,17H,3,8-9,11-16H2,(H,25,28) TZHCOSMLWPDCNG-UHFFFAOYSA-N 194770 US9206167, 122 D(2) dopamine receptor Rattus norvegicus 3.3 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194770&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172704 318150531 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347179 CC(=O)Oc1ccc(OCCCN2CCN(CC2)c2cccc3sccc23)c2NC(=O)CCc12 InChI=1S/C26H29N3O4S/c1-18(30)33-22-7-8-23(26-20(22)6-9-25(31)27-26)32-16-3-11-28-12-14-29(15-13-28)21-4-2-5-24-19(21)10-17-34-24/h2,4-5,7-8,10,17H,3,6,9,11-16H2,1H3,(H,27,31) WPVSYMLDMYTFFM-UHFFFAOYSA-N 194771 US9206167, 128 D(2) dopamine receptor Rattus norvegicus 1.3 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172705 318150532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347180 OCc1cc2CCC(=O)Nc2cc1OCCCN1CCN(CC1)c1cccc2sccc12 InChI=1S/C25H29N3O3S/c29-17-19-15-18-5-6-25(30)26-21(18)16-23(19)31-13-2-8-27-9-11-28(12-10-27)22-3-1-4-24-20(22)7-14-32-24/h1,3-4,7,14-16,29H,2,5-6,8-13,17H2,(H,26,30) KVJMESRMJOEXDV-UHFFFAOYSA-N 194772 US9206167, 139 D(2) dopamine receptor Rattus norvegicus 0.2 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194772&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172706 318150533 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347181 CC(=O)Nc1ccc(OCCCN2CCN(CC2)c2cccc3sccc23)c2CCC(=O)Nc12 InChI=1S/C26H30N4O3S/c1-18(31)27-21-7-8-23(20-6-9-25(32)28-26(20)21)33-16-3-11-29-12-14-30(15-13-29)22-4-2-5-24-19(22)10-17-34-24/h2,4-5,7-8,10,17H,3,6,9,11-16H2,1H3,(H,27,31)(H,28,32) NXFPGCRBHMXTFS-UHFFFAOYSA-N 194773 US9206167, 155 D(2) dopamine receptor Rattus norvegicus 2.3 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194773&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172707 318150534 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347182 Clc1cc2CCC(=O)Nc2c(Cl)c1OCCCN1CCN(CC1)c1cccc2sccc12 InChI=1S/C24H25Cl2N3O2S/c25-18-15-16-5-6-21(30)27-23(16)22(26)24(18)31-13-2-8-28-9-11-29(12-10-28)19-3-1-4-20-17(19)7-14-32-20/h1,3-4,7,14-15H,2,5-6,8-13H2,(H,27,30) JZSNKKRPZJCHQV-UHFFFAOYSA-N 194774 US9206167, 163 D(2) dopamine receptor Rattus norvegicus 2.8 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172708 318150535 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347183 Fc1cc(OCCCCN2CCN(CC2)c2cccc3sccc23)cc2ccc(=O)[nH]c12 InChI=1S/C25H26FN3O2S/c26-21-17-19(16-18-6-7-24(30)27-25(18)21)31-14-2-1-9-28-10-12-29(13-11-28)22-4-3-5-23-20(22)8-15-32-23/h3-8,15-17H,1-2,9-14H2,(H,27,30) OHNZSCWKWZLLOG-UHFFFAOYSA-N 194775 US9206167, 184::USRE48059, Compound of Example 118 D(2) dopamine receptor Rattus norvegicus 2.6 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172709 318150536 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347184 Cc1cc(=O)[nH]c2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc12 InChI=1S/C26H29N3O2S/c1-19-17-26(30)27-23-8-7-20(18-22(19)23)31-15-3-2-10-28-11-13-29(14-12-28)24-5-4-6-25-21(24)9-16-32-25/h4-9,16-18H,2-3,10-15H2,1H3,(H,27,30) XVWAQKVKYOOITD-UHFFFAOYSA-N 194776 US9206167, 185 D(2) dopamine receptor Rattus norvegicus 2.7 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194776&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172710 318150537 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347185 O=C1CCc2cccc(OCCCCN3CCN(CC3)c3cccc4sccc34)c2N1 InChI=1S/C25H29N3O2S/c29-24-10-9-19-5-3-7-22(25(19)26-24)30-17-2-1-12-27-13-15-28(16-14-27)21-6-4-8-23-20(21)11-18-31-23/h3-8,11,18H,1-2,9-10,12-17H2,(H,26,29) CBNYHELABKZQEM-UHFFFAOYSA-N 194777 US9206167, 186 D(2) dopamine receptor Rattus norvegicus 2.3 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172711 318150538 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347186 O=c1ccc2cccc(OCCCCN3CCN(CC3)c3cccc4sccc34)c2[nH]1 InChI=1S/C25H27N3O2S/c29-24-10-9-19-5-3-7-22(25(19)26-24)30-17-2-1-12-27-13-15-28(16-14-27)21-6-4-8-23-20(21)11-18-31-23/h3-11,18H,1-2,12-17H2,(H,26,29) UUYQVYOWXJXSAJ-UHFFFAOYSA-N 194778 US9206167, 188 D(2) dopamine receptor Rattus norvegicus 1.6 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172712 318150539 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 347187 Oc1ccc(OCCCN2CCN(CC2)c2cccc3sccc23)c2NC(=O)CCc12 InChI=1S/C24H27N3O3S/c28-20-6-7-21(24-18(20)5-8-23(29)25-24)30-15-2-10-26-11-13-27(14-12-26)19-3-1-4-22-17(19)9-16-31-22/h1,3-4,6-7,9,16,28H,2,5,8,10-15H2,(H,25,29) VEWLDOIUSVOMEI-UHFFFAOYSA-N 194779 US9206167, 190 D(2) dopamine receptor Rattus norvegicus 0.8 7.4 25.00 C US Patent 10.7270/Q2XD10GS aid1801971 US9206167 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Otsuka Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194779&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172713 318150540 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000630 OC1CCN(CCCCCOc2ccc3oc(cc(=O)c3c2)C2CCCCC2)CC1 InChI=1S/C25H35NO4/c27-20-11-14-26(15-12-20)13-5-2-6-16-29-21-9-10-24-22(17-21)23(28)18-25(30-24)19-7-3-1-4-8-19/h9-10,17-20,27H,1-8,11-16H2 DHWCLSSOUOPVES-UHFFFAOYSA-N 50000575 2-Cyclohexyl-6-[5-(4-hydroxy-piperidin-1-yl)-pentyloxy]-chromen-4-one::CHEMBL37149 D(2) dopamine receptor Rattus norvegicus 12000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983041 103915123 CHEMBL37149 ZINC12356334 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000631 CN(C)CCCCCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C24H29NO3/c1-25(2)15-9-4-3-5-10-16-27-20-13-14-23-21(17-20)22(26)18-24(28-23)19-11-7-6-8-12-19/h6-8,11-14,17-18H,3-5,9-10,15-16H2,1-2H3 JQMFSLWEODIEAO-UHFFFAOYSA-N 50000576 6-(7-Dimethylamino-heptyloxy)-2-phenyl-chromen-4-one::CHEMBL37186 D(2) dopamine receptor Rattus norvegicus 12000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982954 103915124 CHEMBL37186 ZINC13454301 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000635 OC1CCN(CCCCCCCOc2cccc3oc(cc(=O)c23)-c2ccccc2)CC1 InChI=1S/C27H33NO4/c29-22-14-17-28(18-15-22)16-7-2-1-3-8-19-31-24-12-9-13-25-27(24)23(30)20-26(32-25)21-10-5-4-6-11-21/h4-6,9-13,20,22,29H,1-3,7-8,14-19H2 AMINWDBXDFTOJB-UHFFFAOYSA-N 50000580 5-[7-(4-Hydroxy-piperidin-1-yl)-heptyloxy]-2-phenyl-chromen-4-one::CHEMBL38294 D(2) dopamine receptor Rattus norvegicus 2400 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000580&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285332 103915128 CHEMBL38294 ZINC13454272 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000637 O=c1cc(oc2ccc(OCCCCCCN3CCCCC3)cc12)-c1cccs1 InChI=1S/C24H29NO3S/c26-21-18-23(24-9-8-16-29-24)28-22-11-10-19(17-20(21)22)27-15-7-2-1-4-12-25-13-5-3-6-14-25/h8-11,16-18H,1-7,12-15H2 ASAIZTYPKBAHRO-UHFFFAOYSA-N 50000582 6-(6-Piperidin-1-yl-hexyloxy)-2-thiophen-2-yl-chromen-4-one::CHEMBL36491 D(2) dopamine receptor Rattus norvegicus 1400 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000582&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983048 103915130 CHEMBL36491 ZINC13454482 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000643 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2Cl)CC1 InChI=1S/C26H30ClNO4/c27-23-8-4-3-7-21(23)26-18-24(30)22-17-20(9-10-25(22)32-26)31-16-6-2-1-5-13-28-14-11-19(29)12-15-28/h3-4,7-10,17-19,29H,1-2,5-6,11-16H2 LLQGADIELBOEGZ-UHFFFAOYSA-N 50000583 2-(2-Chloro-phenyl)-6-[6-(4-hydroxy-piperidin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL289767 D(2) dopamine receptor Rattus norvegicus 4100 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000583&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983027 103915131 CHEMBL289767 ZINC13454411 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000645 OC1CCN(CCCCCCOc2ccc3c(c2)oc(cc3=O)-c2ccccc2)CC1 InChI=1S/C26H31NO4/c28-21-12-15-27(16-13-21)14-6-1-2-7-17-30-22-10-11-23-24(29)19-25(31-26(23)18-22)20-8-4-3-5-9-20/h3-5,8-11,18-19,21,28H,1-2,6-7,12-17H2 OXULVTWMNORDCF-UHFFFAOYSA-N 50000587 7-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-phenyl-chromen-4-one::CHEMBL39809 D(2) dopamine receptor Rattus norvegicus 6000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982994 103915135 CHEMBL39809 ZINC12356394 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000647 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2cccc(F)c2)CC1 InChI=1S/C26H30FNO4/c27-20-7-5-6-19(16-20)26-18-24(30)23-17-22(8-9-25(23)32-26)31-15-4-2-1-3-12-28-13-10-21(29)11-14-28/h5-9,16-18,21,29H,1-4,10-15H2 XPPJXWWWTLEKQE-UHFFFAOYSA-N 50000590 2-(3-Fluoro-phenyl)-6-[6-(4-hydroxy-piperidin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL38460 D(2) dopamine receptor Rattus norvegicus 11000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000590&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983030 103915138 CHEMBL38460 ZINC13454421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000653 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccncc2)CC1 InChI=1S/C25H30N2O4/c28-20-9-14-27(15-10-20)13-3-1-2-4-16-30-21-5-6-24-22(17-21)23(29)18-25(31-24)19-7-11-26-12-8-19/h5-8,11-12,17-18,20,28H,1-4,9-10,13-16H2 GPVSHWFCGTYUGK-UHFFFAOYSA-N 50000596 6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-pyridin-4-yl-chromen-4-one::CHEMBL289924 D(2) dopamine receptor Rattus norvegicus 6900 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000596&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983038 103915144 CHEMBL289924 ZINC12356391 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000656 CCN(CC)CCCCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C25H31NO3/c1-3-26(4-2)16-10-5-6-11-17-28-21-14-15-24-22(18-21)23(27)19-25(29-24)20-12-8-7-9-13-20/h7-9,12-15,18-19H,3-6,10-11,16-17H2,1-2H3 PALDCHIOOFOOFB-UHFFFAOYSA-N 50000595 6-(6-Diethylamino-hexyloxy)-2-phenyl-chromen-4-one::CHEMBL38323 D(2) dopamine receptor Rattus norvegicus 3600 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982970 103915143 CHEMBL38323 ZINC13454363 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000658 CCOC(=O)C1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C29H35NO5/c1-2-33-29(32)23-14-17-30(18-15-23)16-8-3-4-9-19-34-24-12-13-27-25(20-24)26(31)21-28(35-27)22-10-6-5-7-11-22/h5-7,10-13,20-21,23H,2-4,8-9,14-19H2,1H3 ZXEKOBFUIBKWPJ-UHFFFAOYSA-N 50000597 1-[6-(4-Oxo-2-phenyl-4H-chromen-6-yloxy)-hexyl]-piperidine-4-carboxylic acid ethyl ester::CHEMBL38708 D(2) dopamine receptor Rattus norvegicus 2800 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000597&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982979 103915145 CHEMBL38708 ZINC13454401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000660 CN(C)CCOc1ccc2c(c1)oc(cc2=O)-c1ccccc1 InChI=1S/C19H19NO3/c1-20(2)10-11-22-15-8-9-16-17(21)13-18(23-19(16)12-15)14-6-4-3-5-7-14/h3-9,12-13H,10-11H2,1-2H3 SMIVWJCBSIJRRL-UHFFFAOYSA-N 50000602 7-(2-Dimethylamino-ethoxy)-2-phenyl-chromen-4-one::CHEMBL37088 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121180 103915150 CHEMBL37088 ZINC05957935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000664 OC1CCN(CCCCCCOc2cccc3c2oc(cc3=O)-c2ccccc2)CC1 InChI=1S/C26H31NO4/c28-21-13-16-27(17-14-21)15-6-1-2-7-18-30-24-12-8-11-22-23(29)19-25(31-26(22)24)20-9-4-3-5-10-20/h3-5,8-12,19,21,28H,1-2,6-7,13-18H2 AWSGYSUHPNLJPO-UHFFFAOYSA-N 50000574 8-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-phenyl-chromen-4-one::CHEMBL291300 D(2) dopamine receptor Rattus norvegicus 940 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982997 103915122 CHEMBL291300 ZINC12356401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000666 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2cccc(Cl)c2)CC1 InChI=1S/C26H30ClNO4/c27-20-7-5-6-19(16-20)26-18-24(30)23-17-22(8-9-25(23)32-26)31-15-4-2-1-3-12-28-13-10-21(29)11-14-28/h5-9,16-18,21,29H,1-4,10-15H2 SLVDSHANYGRJLH-UHFFFAOYSA-N 50000598 2-(3-Chloro-phenyl)-6-[6-(4-hydroxy-piperidin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL38514 D(2) dopamine receptor Rattus norvegicus 6400 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000598&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983029 103915146 CHEMBL38514 ZINC13454418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000668 O=c1cc(oc2ccc(OCCCCCCN3CCCCC3)cc12)-c1ccccc1 InChI=1S/C26H31NO3/c28-24-20-26(21-11-5-3-6-12-21)30-25-14-13-22(19-23(24)25)29-18-10-2-1-7-15-27-16-8-4-9-17-27/h3,5-6,11-14,19-20H,1-2,4,7-10,15-18H2 CQUBQMZYVNPVPN-UHFFFAOYSA-N 50000592 2-Phenyl-6-(6-piperidin-1-yl-hexyloxy)-chromen-4-one::CHEMBL40676 D(2) dopamine receptor Rattus norvegicus 4500 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000592&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982965 103915140 CHEMBL40676 ZINC13454334 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000670 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2cccs2)CC1 InChI=1S/C24H29NO4S/c26-18-9-12-25(13-10-18)11-3-1-2-4-14-28-19-7-8-22-20(16-19)21(27)17-23(29-22)24-6-5-15-30-24/h5-8,15-18,26H,1-4,9-14H2 IYZKNKNHPCKKSN-UHFFFAOYSA-N 50000604 6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-thiophen-2-yl-chromen-4-one::CHEMBL36928 D(2) dopamine receptor Rattus norvegicus 4000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000604&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983028 103915152 CHEMBL36928 ZINC13454414 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000672 OC1CCN(CCCCOc2cccc3oc(cc(=O)c23)-c2ccccc2)CC1 InChI=1S/C24H27NO4/c26-19-11-14-25(15-12-19)13-4-5-16-28-21-9-6-10-22-24(21)20(27)17-23(29-22)18-7-2-1-3-8-18/h1-3,6-10,17,19,26H,4-5,11-16H2 NIXHGJLLEYNHAV-UHFFFAOYSA-N 50000599 5-[4-(4-Hydroxy-piperidin-1-yl)-butoxy]-2-phenyl-chromen-4-one::CHEMBL40016 D(2) dopamine receptor Rattus norvegicus 9500 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000599&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18959714 103915147 CHEMBL40016 ZINC12356284 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000673 OC1CCN(CCCCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C28H35NO4/c30-23-14-17-29(18-15-23)16-8-3-1-2-4-9-19-32-24-12-13-27-25(20-24)26(31)21-28(33-27)22-10-6-5-7-11-22/h5-7,10-13,20-21,23,30H,1-4,8-9,14-19H2 LPJXCFFEPQABJE-UHFFFAOYSA-N 50000609 6-[8-(4-Hydroxy-piperidin-1-yl)-octyloxy]-2-phenyl-chromen-4-one::CHEMBL39615 D(2) dopamine receptor Rattus norvegicus 8900 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000609&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18959739 103915157 CHEMBL39615 ZINC13454325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000675 O=c1cc(oc2ccc(OCCCCCCN3CCNCC3c3ncccn3)cc12)-c1ccccc1 InChI=1S/C29H32N4O3/c34-26-20-28(22-9-4-3-5-10-22)36-27-12-11-23(19-24(26)27)35-18-7-2-1-6-16-33-17-15-30-21-25(33)29-31-13-8-14-32-29/h3-5,8-14,19-20,25,30H,1-2,6-7,15-18,21H2 IMSBLSSUHKSGTN-UHFFFAOYSA-N 50000606 2-Phenyl-6-[6-(2-pyrimidin-2-yl-piperazin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL39584 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000606&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285702 103915154 CHEMBL39584 ZINC29327971 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000677 CN(C)CCCCCCCCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C27H35NO3/c1-28(2)18-12-7-5-3-4-6-8-13-19-30-23-16-17-26-24(20-23)25(29)21-27(31-26)22-14-10-9-11-15-22/h9-11,14-17,20-21H,3-8,12-13,18-19H2,1-2H3 BPNSQEIRCIDVME-UHFFFAOYSA-N 50000593 6-(10-Dimethylamino-decyloxy)-2-phenyl-chromen-4-one::CHEMBL36966 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000593&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982957 103915141 CHEMBL36966 ZINC13454311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000687 COc1c(oc2ccc(OCCCCCCN3CCC(O)CC3)cc2c1=O)-c1ccccc1 InChI=1S/C27H33NO5/c1-31-27-25(30)23-19-22(11-12-24(23)33-26(27)20-9-5-4-6-10-20)32-18-8-3-2-7-15-28-16-13-21(29)14-17-28/h4-6,9-12,19,21,29H,2-3,7-8,13-18H2,1H3 GLPQOACEPRECSA-UHFFFAOYSA-N 50000613 6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-3-methoxy-2-phenyl-chromen-4-one::CHEMBL37470 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000613&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983055 103915161 CHEMBL37470 ZINC13454497 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000693 O=c1cc(oc2ccc(OCCCCCCN3CCCCCC3)cc12)-c1ccccc1 InChI=1S/C27H33NO3/c29-25-21-27(22-12-6-5-7-13-22)31-26-15-14-23(20-24(25)26)30-19-11-4-3-10-18-28-16-8-1-2-9-17-28/h5-7,12-15,20-21H,1-4,8-11,16-19H2 YRWAQBPKMXQEMV-UHFFFAOYSA-N 50000603 6-(6-Azepan-1-yl-hexyloxy)-2-phenyl-chromen-4-one::CHEMBL432859 D(2) dopamine receptor Rattus norvegicus 2300 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000603&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982966 103915151 CHEMBL432859 ZINC13454340 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000694 Cc1c(oc2ccc(OCCC\C=C\CN3CCC(O)CC3)cc2c1=O)-c1ccccc1 InChI=1S/C27H31NO4/c1-20-26(30)24-19-23(11-12-25(24)32-27(20)21-9-5-4-6-10-21)31-18-8-3-2-7-15-28-16-13-22(29)14-17-28/h2,4-7,9-12,19,22,29H,3,8,13-18H2,1H3/b7-2+ CKLFEYSBTIDHIS-FARCUNLSSA-N 50000594 6-[6-(4-Hydroxy-piperidin-1-yl)-hex-4-enyloxy]-3-methyl-2-phenyl-chromen-4-one::CHEMBL440606 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285740 103915142 CHEMBL440606 ZINC29328844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000699 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)C2CCCCC2)CC1 InChI=1S/C26H37NO4/c28-21-12-15-27(16-13-21)14-6-1-2-7-17-30-22-10-11-25-23(18-22)24(29)19-26(31-25)20-8-4-3-5-9-20/h10-11,18-21,28H,1-9,12-17H2 VCYLVMUSUVMOGL-UHFFFAOYSA-N 50000619 2-Cyclohexyl-6-[6-(4-hydroxy-piperidin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL39583 D(2) dopamine receptor Rattus norvegicus 25000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000619&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983042 103915167 CHEMBL39583 ZINC13454447 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000701 OC1CCN(CCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C25H29NO4/c27-20-11-14-26(15-12-20)13-5-2-6-16-29-21-9-10-24-22(17-21)23(28)18-25(30-24)19-7-3-1-4-8-19/h1,3-4,7-10,17-18,20,27H,2,5-6,11-16H2 OFMBGQSIBSOXBL-UHFFFAOYSA-N 50000589 6-[5-(4-Hydroxy-piperidin-1-yl)-pentyloxy]-2-phenyl-chromen-4-one::CHEMBL38047 D(2) dopamine receptor Rattus norvegicus 5100 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000589&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18959700 103915137 CHEMBL38047 ZINC13454314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000702 CN(C)CCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C21H23NO3/c1-22(2)12-6-7-13-24-17-10-11-20-18(14-17)19(23)15-21(25-20)16-8-4-3-5-9-16/h3-5,8-11,14-15H,6-7,12-13H2,1-2H3 RNSJXWMAYUTWOI-UHFFFAOYSA-N 50000601 6-(4-Dimethylamino-butoxy)-2-phenyl-chromen-4-one::CHEMBL287894 D(2) dopamine receptor Rattus norvegicus 4200 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982951 103915149 CHEMBL287894 ZINC13454287 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000704 OC1CCN(CCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C23H25NO4/c25-18-9-12-24(13-10-18)11-4-14-27-19-7-8-22-20(15-19)21(26)16-23(28-22)17-5-2-1-3-6-17/h1-3,5-8,15-16,18,25H,4,9-14H2 MBZZPQUBYDXAHT-UHFFFAOYSA-N 50000626 6-[3-(4-Hydroxy-piperidin-1-yl)-propoxy]-2-phenyl-chromen-4-one::CHEMBL38264 D(2) dopamine receptor Rattus norvegicus 3400 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000626&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285419 103915174 CHEMBL38264 ZINC12356249 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000710 OC1CCCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)C1 InChI=1S/C26H31NO4/c28-21-11-8-15-27(19-21)14-6-1-2-7-16-30-22-12-13-25-23(17-22)24(29)18-26(31-25)20-9-4-3-5-10-20/h3-5,9-10,12-13,17-18,21,28H,1-2,6-8,11,14-16,19H2 HMQKIWOBTLZLLA-UHFFFAOYSA-N 50000600 6-[6-(3-Hydroxy-piperidin-1-yl)-hexyloxy]-2-phenyl-chromen-4-one::CHEMBL40278 D(2) dopamine receptor Rattus norvegicus 5500 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000600&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982961 103915148 CHEMBL40278 ZINC13454350 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000711 O=c1cc(oc2ccc(OCCCCCCN3CCNCC3c3ccccn3)cc12)-c1ccccc1 InChI=1S/C30H33N3O3/c34-28-21-30(23-10-4-3-5-11-23)36-29-14-13-24(20-25(28)29)35-19-9-2-1-8-17-33-18-16-31-22-27(33)26-12-6-7-15-32-26/h3-7,10-15,20-21,27,31H,1-2,8-9,16-19,22H2 FOTDOIGKSDTJRO-UHFFFAOYSA-N 50000615 2-Phenyl-6-[6-(2-pyridin-2-yl-piperazin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL37468 D(2) dopamine receptor Rattus norvegicus 3000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000615&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285300 103915163 CHEMBL37468 ZINC29322308 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000712 O=c1cc(oc2ccc(OCCCCCCN3CCCCC3)cc12)C1CCCC1 InChI=1S/C25H35NO3/c27-23-19-25(20-10-4-5-11-20)29-24-13-12-21(18-22(23)24)28-17-9-2-1-6-14-26-15-7-3-8-16-26/h12-13,18-20H,1-11,14-17H2 KGKQZJYUVGMBOX-UHFFFAOYSA-N 50000623 2-Cyclopentyl-6-(6-piperidin-1-yl-hexyloxy)-chromen-4-one::CHEMBL288466 D(2) dopamine receptor Rattus norvegicus 3200 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000623&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983054 103915171 CHEMBL288466 ZINC13454468 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000715 O=c1cc(oc2ccc(OCCCCCCN3CCCCC3)cc12)-c1ccncc1 InChI=1S/C25H30N2O3/c28-23-19-25(20-10-12-26-13-11-20)30-24-9-8-21(18-22(23)24)29-17-7-2-1-4-14-27-15-5-3-6-16-27/h8-13,18-19H,1-7,14-17H2 ADPUUXSSYIILOK-UHFFFAOYSA-N 50000620 6-(6-Piperidin-1-yl-hexyloxy)-2-pyridin-4-yl-chromen-4-one::CHEMBL290612 D(2) dopamine receptor Rattus norvegicus 1800 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000620&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983050 103915168 CHEMBL290612 ZINC13454488 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000716 OC1CCN(CCCCCOc2ccc3c(c2)oc(cc3=O)-c2ccccc2)CC1 InChI=1S/C25H29NO4/c27-20-11-14-26(15-12-20)13-5-2-6-16-29-21-9-10-22-23(28)18-24(30-25(22)17-21)19-7-3-1-4-8-19/h1,3-4,7-10,17-18,20,27H,2,5-6,11-16H2 MERGDWKYNIQHBP-UHFFFAOYSA-N 50000627 7-[5-(4-Hydroxy-piperidin-1-yl)-pentyloxy]-2-phenyl-chromen-4-one::CHEMBL39941 D(2) dopamine receptor Rattus norvegicus 5900 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000627&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982993 103915175 CHEMBL39941 ZINC12356336 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000717 OCCC1CC(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CCN1 InChI=1S/C28H35NO4/c30-16-14-23-18-21(13-15-29-23)8-4-1-2-7-17-32-24-11-12-27-25(19-24)26(31)20-28(33-27)22-9-5-3-6-10-22/h3,5-6,9-12,19-21,23,29-30H,1-2,4,7-8,13-18H2 ILHCFXHHSGJCMQ-UHFFFAOYSA-N 50000573 6-{6-[2-(2-Hydroxy-ethyl)-piperidin-4-yl]-hexyloxy}-2-phenyl-chromen-4-one::CHEMBL39713 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285462 103915121 CHEMBL39713 ZINC29322959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000722 CN(C)CCCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C22H25NO3/c1-23(2)13-7-4-8-14-25-18-11-12-21-19(15-18)20(24)16-22(26-21)17-9-5-3-6-10-17/h3,5-6,9-12,15-16H,4,7-8,13-14H2,1-2H3 DKSDLSUPQYIZAA-UHFFFAOYSA-N 50000625 6-(5-Dimethylamino-pentyloxy)-2-phenyl-chromen-4-one::CHEMBL38392 D(2) dopamine receptor Rattus norvegicus 8200 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000625&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982952 103915173 CHEMBL38392 ZINC13454293 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000723 O=c1cc(oc2ccc(OCCCCCCN3CCOCC3)cc12)-c1ccccc1 InChI=1S/C25H29NO4/c27-23-19-25(20-8-4-3-5-9-20)30-24-11-10-21(18-22(23)24)29-15-7-2-1-6-12-26-13-16-28-17-14-26/h3-5,8-11,18-19H,1-2,6-7,12-17H2 LMLOVKBFKXDYEE-UHFFFAOYSA-N 50000586 6-(6-Morpholin-4-yl-hexyloxy)-2-phenyl-chromen-4-one::CHEMBL38322 D(2) dopamine receptor Rattus norvegicus 18000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982971 103915134 CHEMBL38322 ZINC13454366 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000724 OC1CCN(CCCCCCCCOc2ccc3c(c2)oc(cc3=O)-c2ccccc2)CC1 InChI=1S/C28H35NO4/c30-23-14-17-29(18-15-23)16-8-3-1-2-4-9-19-32-24-12-13-25-26(31)21-27(33-28(25)20-24)22-10-6-5-7-11-22/h5-7,10-13,20-21,23,30H,1-4,8-9,14-19H2 VLRNLXJDYGVNIK-UHFFFAOYSA-N 50000633 7-[8-(4-Hydroxy-piperidin-1-yl)-octyloxy]-2-phenyl-chromen-4-one::CHEMBL35714 D(2) dopamine receptor Rattus norvegicus 2800 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000633&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982996 103915181 CHEMBL35714 ZINC13454494 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000733 CN(CCCCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1)Cc1ccccc1 InChI=1S/C29H31NO3/c1-30(22-23-12-6-4-7-13-23)18-10-2-3-11-19-32-25-16-17-28-26(20-25)27(31)21-29(33-28)24-14-8-5-9-15-24/h4-9,12-17,20-21H,2-3,10-11,18-19,22H2,1H3 XXTUDZIPHKNILV-UHFFFAOYSA-N 50000578 6-[6-(Benzyl-methyl-amino)-hexyloxy]-2-phenyl-chromen-4-one::CHEMBL38809 D(2) dopamine receptor Rattus norvegicus 1800 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982969 103915126 CHEMBL38809 ZINC13454357 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000735 OC1CCN(CCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C24H27NO4/c26-19-10-13-25(14-11-19)12-4-5-15-28-20-8-9-23-21(16-20)22(27)17-24(29-23)18-6-2-1-3-7-18/h1-3,6-9,16-17,19,26H,4-5,10-15H2 GUFWLMZMZSIYHJ-UHFFFAOYSA-N 50000630 6-[4-(4-Hydroxy-piperidin-1-yl)-butoxy]-2-phenyl-chromen-4-one::CHEMBL37508 D(2) dopamine receptor Rattus norvegicus 6800 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000630&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18959716 103915178 CHEMBL37508 ZINC12356285 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000738 COc1ccc(cc1)-c1cc(=O)c2cc(OCCCCCN3CCC(O)CC3)ccc2o1 InChI=1S/C26H31NO5/c1-30-21-7-5-19(6-8-21)26-18-24(29)23-17-22(9-10-25(23)32-26)31-16-4-2-3-13-27-14-11-20(28)12-15-27/h5-10,17-18,20,28H,2-4,11-16H2,1H3 HGUUVZKRCZAQKY-UHFFFAOYSA-N 50000612 6-[5-(4-Hydroxy-piperidin-1-yl)-pentyloxy]-2-(4-methoxy-phenyl)-chromen-4-one::CHEMBL38023 D(2) dopamine receptor Rattus norvegicus 4200 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000612&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983036 103915160 CHEMBL38023 ZINC13454441 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000739 Cc1c(oc2ccc(OCCCCCCN3CCC(O)CC3)cc2c1=O)-c1ccccc1 InChI=1S/C27H33NO4/c1-20-26(30)24-19-23(11-12-25(24)32-27(20)21-9-5-4-6-10-21)31-18-8-3-2-7-15-28-16-13-22(29)14-17-28/h4-6,9-12,19,22,29H,2-3,7-8,13-18H2,1H3 RFUIYSLMVBVREF-UHFFFAOYSA-N 50000638 6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-3-methyl-2-phenyl-chromen-4-one::CHEMBL38862 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9890959 103915186 CHEMBL38862 ZINC01533379 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000740 NCCCCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C21H23NO3/c22-12-6-1-2-7-13-24-17-10-11-20-18(14-17)19(23)15-21(25-20)16-8-4-3-5-9-16/h3-5,8-11,14-15H,1-2,6-7,12-13,22H2 CTQGVUFBEMLQKE-UHFFFAOYSA-N 50000588 6-(6-Amino-hexyloxy)-2-phenyl-chromen-4-one::CHEMBL36675 D(2) dopamine receptor Rattus norvegicus 8200 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000588&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982984 103915136 CHEMBL36675 ZINC13454504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000744 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2cccnc2)CC1 InChI=1S/C25H30N2O4/c28-20-9-13-27(14-10-20)12-3-1-2-4-15-30-21-7-8-24-22(16-21)23(29)17-25(31-24)19-6-5-11-26-18-19/h5-8,11,16-18,20,28H,1-4,9-10,12-15H2 GNOWCEMSRMWHRN-UHFFFAOYSA-N 50000639 6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-pyridin-3-yl-chromen-4-one::CHEMBL39203 D(2) dopamine receptor Rattus norvegicus 3800 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000639&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983033 103915187 CHEMBL39203 ZINC13454430 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000745 Clc1ccccc1-c1cc(=O)c2cc(OCCCCCCN3CCCCC3)ccc2o1 InChI=1S/C26H30ClNO3/c27-23-11-5-4-10-21(23)26-19-24(29)22-18-20(12-13-25(22)31-26)30-17-9-2-1-6-14-28-15-7-3-8-16-28/h4-5,10-13,18-19H,1-3,6-9,14-17H2 KHUROPCMDYNJNA-UHFFFAOYSA-N 50000622 2-(2-Chloro-phenyl)-6-(6-piperidin-1-yl-hexyloxy)-chromen-4-one::CHEMBL37138 D(2) dopamine receptor Rattus norvegicus 2200 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000622&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983047 103915170 CHEMBL37138 ZINC13454477 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000747 O=c1cc(oc2ccc(OCCCCCCN3CCCCC3)cc12)C1CCCCC1 InChI=1S/C26H37NO3/c28-24-20-26(21-11-5-3-6-12-21)30-25-14-13-22(19-23(24)25)29-18-10-2-1-7-15-27-16-8-4-9-17-27/h13-14,19-21H,1-12,15-18H2 PINMZOXVOLYEEJ-UHFFFAOYSA-N 50000644 2-Cyclohexyl-6-(6-piperidin-1-yl-hexyloxy)-chromen-4-one::CHEMBL412640 D(2) dopamine receptor Rattus norvegicus 7700 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983046 103915192 CHEMBL412640 ZINC13454472 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000750 CN(C)CCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C20H21NO3/c1-21(2)11-6-12-23-16-9-10-19-17(13-16)18(22)14-20(24-19)15-7-4-3-5-8-15/h3-5,7-10,13-14H,6,11-12H2,1-2H3 ZYNLWVKBNSEHTK-UHFFFAOYSA-N 50000628 6-(3-Dimethylamino-propoxy)-2-phenyl-chromen-4-one::CHEMBL38983 D(2) dopamine receptor Rattus norvegicus 3600 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000628&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982950 103915176 CHEMBL38983 ZINC13454282 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000755 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)C2CCC2)CC1 InChI=1S/C24H33NO4/c26-19-10-13-25(14-11-19)12-3-1-2-4-15-28-20-8-9-23-21(16-20)22(27)17-24(29-23)18-6-5-7-18/h8-9,16-19,26H,1-7,10-15H2 CTUFOSUSILTDOK-UHFFFAOYSA-N 50000621 2-Cyclobutyl-6-[6-(4-hydroxy-piperidin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL40115 D(2) dopamine receptor Rattus norvegicus 14000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000621&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983039 103915169 CHEMBL40115 ZINC12356283 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000756 OC1CCN(CCCCCOc2cccc3oc(cc(=O)c23)-c2ccccc2)CC1 InChI=1S/C25H29NO4/c27-20-12-15-26(16-13-20)14-5-2-6-17-29-22-10-7-11-23-25(22)21(28)18-24(30-23)19-8-3-1-4-9-19/h1,3-4,7-11,18,20,27H,2,5-6,12-17H2 AUSXRTGVWVREMJ-UHFFFAOYSA-N 50000640 5-[5-(4-Hydroxy-piperidin-1-yl)-pentyloxy]-2-phenyl-chromen-4-one::CHEMBL412429 D(2) dopamine receptor Rattus norvegicus 5100 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000640&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18959702 103915188 CHEMBL412429 ZINC12356339 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000759 OC1CCN(CCCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C27H33NO4/c29-22-13-16-28(17-14-22)15-7-2-1-3-8-18-31-23-11-12-26-24(19-23)25(30)20-27(32-26)21-9-5-4-6-10-21/h4-6,9-12,19-20,22,29H,1-3,7-8,13-18H2 FHRQHMSKFPTJSL-UHFFFAOYSA-N 50000637 6-[7-(4-Hydroxy-piperidin-1-yl)-heptyloxy]-2-phenyl-chromen-4-one::CHEMBL39638 D(2) dopamine receptor Rattus norvegicus 6500 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18959715 103915185 CHEMBL39638 ZINC13454322 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000762 O=c1cc(oc2ccc(OCCCCCCN3CCCCC3)cc12)-c1cccnc1 InChI=1S/C25H30N2O3/c28-23-18-25(20-9-8-12-26-19-20)30-24-11-10-21(17-22(23)24)29-16-7-2-1-4-13-27-14-5-3-6-15-27/h8-12,17-19H,1-7,13-16H2 CCDAXHSDQCUZEE-UHFFFAOYSA-N 50000585 6-(6-Piperidin-1-yl-hexyloxy)-2-pyridin-3-yl-chromen-4-one::CHEMBL39163 D(2) dopamine receptor Rattus norvegicus 2300 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000585&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983049 103915133 CHEMBL39163 ZINC13454485 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000764 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccc(Cl)cc2)CC1 InChI=1S/C26H30ClNO4/c27-20-7-5-19(6-8-20)26-18-24(30)23-17-22(9-10-25(23)32-26)31-16-4-2-1-3-13-28-14-11-21(29)12-15-28/h5-10,17-18,21,29H,1-4,11-16H2 GFJGJSGIMWXSNX-UHFFFAOYSA-N 50000608 2-(4-Chloro-phenyl)-6-[6-(4-hydroxy-piperidin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL39202 D(2) dopamine receptor Rattus norvegicus 11000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000608&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983034 103915156 CHEMBL39202 ZINC13454435 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000768 O=C1NCN(c2ccccc2)C11CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C34H37N3O4/c38-30-24-32(26-11-5-3-6-12-26)41-31-16-15-28(23-29(30)31)40-22-10-2-1-9-19-36-20-17-34(18-21-36)33(39)35-25-37(34)27-13-7-4-8-14-27/h3-8,11-16,23-24H,1-2,9-10,17-22,25H2,(H,35,39) HJPDDBRFRIQQEK-UHFFFAOYSA-N 50000624 8-[6-(4-Oxo-2-phenyl-4H-chromen-6-yloxy)-hexyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL39053 D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000624&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982981 103915172 CHEMBL39053 ZINC29331498 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000769 COc1ccc(cc1)-c1cc(=O)c2cc(OCCCCCCN3CCC(O)CC3)ccc2o1 InChI=1S/C27H33NO5/c1-31-22-8-6-20(7-9-22)27-19-25(30)24-18-23(10-11-26(24)33-27)32-17-5-3-2-4-14-28-15-12-21(29)13-16-28/h6-11,18-19,21,29H,2-5,12-17H2,1H3 SBRZBEXACNXDPV-UHFFFAOYSA-N 50000641 6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-(4-methoxy-phenyl)-chromen-4-one::CHEMBL288148 D(2) dopamine receptor Rattus norvegicus 3700 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000641&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983037 103915189 CHEMBL288148 ZINC13454444 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000771 O=c1cc(oc2ccc(OCCCCCCN3CCCCC3)cc12)C1CCC1 InChI=1S/C24H33NO3/c26-22-18-24(19-9-8-10-19)28-23-12-11-20(17-21(22)23)27-16-7-2-1-4-13-25-14-5-3-6-15-25/h11-12,17-19H,1-10,13-16H2 CUWDNZRRHPYUSF-UHFFFAOYSA-N 50000643 2-Cyclobutyl-6-(6-piperidin-1-yl-hexyloxy)-chromen-4-one::CHEMBL37256 D(2) dopamine receptor Rattus norvegicus 5500 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983053 103915191 CHEMBL37256 ZINC13454462 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000772 CN(C)CCCCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C23H27NO3/c1-24(2)14-8-3-4-9-15-26-19-12-13-22-20(16-19)21(25)17-23(27-22)18-10-6-5-7-11-18/h5-7,10-13,16-17H,3-4,8-9,14-15H2,1-2H3 XAJUVMJPSQZNDC-UHFFFAOYSA-N 50000605 6-(6-Dimethylamino-hexyloxy)-2-phenyl-chromen-4-one::CHEMBL38585 D(2) dopamine receptor Rattus norvegicus 5600 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000605&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982953 103915153 CHEMBL38585 ZINC13454297 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000777 CN(C)CCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C19H19NO3/c1-20(2)10-11-22-15-8-9-18-16(12-15)17(21)13-19(23-18)14-6-4-3-5-7-14/h3-9,12-13H,10-11H2,1-2H3 WTEHNPYGYVPIBD-UHFFFAOYSA-N 50000616 6-(2-Dimethylamino-ethoxy)-2-phenyl-chromen-4-one::CHEMBL418239 D(2) dopamine receptor Rattus norvegicus 4500 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000616&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982949 103915164 CHEMBL418239 ZINC13454277 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000780 Clc1ccc(cc1)N1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C31H33ClN2O3/c32-25-10-12-26(13-11-25)34-19-17-33(18-20-34)16-6-1-2-7-21-36-27-14-15-30-28(22-27)29(35)23-31(37-30)24-8-4-3-5-9-24/h3-5,8-15,22-23H,1-2,6-7,16-21H2 MUONKNLCAXBBSN-UHFFFAOYSA-N 50000646 6-{6-[4-(4-Chloro-phenyl)-piperazin-1-yl]-hexyloxy}-2-phenyl-chromen-4-one::CHEMBL38547 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000646&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982976 103915194 CHEMBL38547 ZINC13454384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000784 Cc1c(oc2ccc(OCCCCCCN3CCC(O)CC3)cc2c1=O)C1CCCCC1 InChI=1S/C27H39NO4/c1-20-26(30)24-19-23(11-12-25(24)32-27(20)21-9-5-4-6-10-21)31-18-8-3-2-7-15-28-16-13-22(29)14-17-28/h11-12,19,21-22,29H,2-10,13-18H2,1H3 MJJLENAWKXKSDR-UHFFFAOYSA-N 50000631 2-Cyclohexyl-6-[6-(4-hydroxy-piperidin-1-yl)-hexyloxy]-3-methyl-chromen-4-one::CHEMBL40113 D(2) dopamine receptor Rattus norvegicus 4700 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000631&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983043 103915179 CHEMBL40113 ZINC13454452 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000786 OC1CCN(CCCCCCCOc2ccc3c(c2)oc(cc3=O)-c2ccccc2)CC1 InChI=1S/C27H33NO4/c29-22-13-16-28(17-14-22)15-7-2-1-3-8-18-31-23-11-12-24-25(30)20-26(32-27(24)19-23)21-9-5-4-6-10-21/h4-6,9-12,19-20,22,29H,1-3,7-8,13-18H2 WEIVNWQRFIAOTQ-UHFFFAOYSA-N 50000610 7-[7-(4-Hydroxy-piperidin-1-yl)-heptyloxy]-2-phenyl-chromen-4-one::CHEMBL38952 D(2) dopamine receptor Rattus norvegicus 4000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000610&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982995 103915158 CHEMBL38952 ZINC13454491 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000789 CC(C)Cc1cc(=O)c2cc(OCCCCCN3CCC(O)CC3)ccc2o1 InChI=1S/C23H33NO4/c1-17(2)14-20-16-22(26)21-15-19(6-7-23(21)28-20)27-13-5-3-4-10-24-11-8-18(25)9-12-24/h6-7,15-18,25H,3-5,8-14H2,1-2H3 SIQDVGDODFEIPG-UHFFFAOYSA-N 50000581 6-[5-(4-Hydroxy-piperidin-1-yl)-pentyloxy]-2-isobutyl-chromen-4-one::CHEMBL39480 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983044 103915129 CHEMBL39480 ZINC13454454 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000795 CC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C27H33NO3/c1-21-13-16-28(17-14-21)15-7-2-3-8-18-30-23-11-12-26-24(19-23)25(29)20-27(31-26)22-9-5-4-6-10-22/h4-6,9-12,19-21H,2-3,7-8,13-18H2,1H3 INEIYXTWSFMWAQ-UHFFFAOYSA-N 50000634 6-[6-(4-Methyl-piperidin-1-yl)-hexyloxy]-2-phenyl-chromen-4-one::CHEMBL289702 D(2) dopamine receptor Rattus norvegicus 570 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000634&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982968 103915182 CHEMBL289702 ZINC13454354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000796 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccc(F)cc2)CC1 InChI=1S/C26H30FNO4/c27-20-7-5-19(6-8-20)26-18-24(30)23-17-22(9-10-25(23)32-26)31-16-4-2-1-3-13-28-14-11-21(29)12-15-28/h5-10,17-18,21,29H,1-4,11-16H2 IFCWRTLMQGRKJJ-UHFFFAOYSA-N 50000577 2-(4-Fluoro-phenyl)-6-[6-(4-hydroxy-piperidin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL38565 D(2) dopamine receptor Rattus norvegicus 3800 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000577&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983035 103915125 CHEMBL38565 ZINC13454438 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000802 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)C2CCCC2)CC1 InChI=1S/C25H35NO4/c27-20-11-14-26(15-12-20)13-5-1-2-6-16-29-21-9-10-24-22(17-21)23(28)18-25(30-24)19-7-3-4-8-19/h9-10,17-20,27H,1-8,11-16H2 OLDFLCQPXMVTBT-UHFFFAOYSA-N 50000636 2-Cyclopentyl-6-[6-(4-hydroxy-piperidin-1-yl)-hexyloxy]-chromen-4-one::CHEMBL37150 D(2) dopamine receptor Rattus norvegicus 21000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983040 103915184 CHEMBL37150 ZINC12356333 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000803 CN(C)CCCCCCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C25H31NO3/c1-26(2)16-10-5-3-4-6-11-17-28-21-14-15-24-22(18-21)23(27)19-25(29-24)20-12-8-7-9-13-20/h7-9,12-15,18-19H,3-6,10-11,16-17H2,1-2H3 KBVFWKXRUWFQFO-UHFFFAOYSA-N 50000629 6-(8-Dimethylamino-octyloxy)-2-phenyl-chromen-4-one::CHEMBL286353 D(2) dopamine receptor Rattus norvegicus 2800 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000629&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982955 103915177 CHEMBL286353 ZINC13454304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000816 CCOC(=O)C1CCCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)C1 InChI=1S/C29H35NO5/c1-2-33-29(32)23-13-10-17-30(21-23)16-8-3-4-9-18-34-24-14-15-27-25(19-24)26(31)20-28(35-27)22-11-6-5-7-12-22/h5-7,11-12,14-15,19-20,23H,2-4,8-10,13,16-18,21H2,1H3 DBWCTMRDXGQFNM-UHFFFAOYSA-N 50000607 1-[6-(4-Oxo-2-phenyl-4H-chromen-6-yloxy)-hexyl]-piperidine-3-carboxylic acid ethyl ester::CHEMBL38896 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000607&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982978 103915155 CHEMBL38896 ZINC13454398 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000822 OC1(CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1)c1ccc(Cl)cc1 InChI=1S/C32H34ClNO4/c33-26-12-10-25(11-13-26)32(36)16-19-34(20-17-32)18-6-1-2-7-21-37-27-14-15-30-28(22-27)29(35)23-31(38-30)24-8-4-3-5-9-24/h3-5,8-15,22-23,36H,1-2,6-7,16-21H2 NWIUHJOQNRALHQ-UHFFFAOYSA-N 50000614 6-{6-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-hexyloxy}-2-phenyl-chromen-4-one::CHEMBL289896 D(2) dopamine receptor Rattus norvegicus 990 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982980 103915162 CHEMBL289896 ZINC13454404 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000823 O=c1cc(oc2ccc(OCCCCCCN3CCOCC3)cc12)C1CCCCC1 InChI=1S/C25H35NO4/c27-23-19-25(20-8-4-3-5-9-20)30-24-11-10-21(18-22(23)24)29-15-7-2-1-6-12-26-13-16-28-17-14-26/h10-11,18-20H,1-9,12-17H2 CWRBRGDSLCSBPC-UHFFFAOYSA-N 50000648 2-Cyclohexyl-6-(6-morpholin-4-yl-hexyloxy)-chromen-4-one::CHEMBL287975 D(2) dopamine receptor Rattus norvegicus 14000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983045 103915196 CHEMBL287975 ZINC13454458 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000825 OC1CCN(CCCOc2cccc3oc(cc(=O)c23)-c2ccccc2)CC1 InChI=1S/C23H25NO4/c25-18-10-13-24(14-11-18)12-5-15-27-20-8-4-9-21-23(20)19(26)16-22(28-21)17-6-2-1-3-7-17/h1-4,6-9,16,18,25H,5,10-15H2 ROUAURUVDJAXOE-UHFFFAOYSA-N 50000635 5-[3-(4-Hydroxy-piperidin-1-yl)-propoxy]-2-phenyl-chromen-4-one::CHEMBL38665 D(2) dopamine receptor Rattus norvegicus 8400 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000635&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18959727 103915183 CHEMBL38665 ZINC12356242 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000826 Clc1ccc(cc1)C1=CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C32H32ClNO3/c33-27-12-10-24(11-13-27)25-16-19-34(20-17-25)18-6-1-2-7-21-36-28-14-15-31-29(22-28)30(35)23-32(37-31)26-8-4-3-5-9-26/h3-5,8-16,22-23H,1-2,6-7,17-21H2 NGOGKKBBHCVORF-UHFFFAOYSA-N 50000642 6-{6-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-hexyloxy}-2-phenyl-chromen-4-one::CHEMBL39001 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982982 103915190 CHEMBL39001 ZINC13454407 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000828 CN(CCO)CCCCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C24H29NO4/c1-25(14-15-26)13-7-2-3-8-16-28-20-11-12-23-21(17-20)22(27)18-24(29-23)19-9-5-4-6-10-19/h4-6,9-12,17-18,26H,2-3,7-8,13-16H2,1H3 GIIVHFWCPKIQJN-UHFFFAOYSA-N 50000649 6-{6-[(2-Hydroxy-ethyl)-methyl-amino]-hexyloxy}-2-phenyl-chromen-4-one::CHEMBL38897 D(2) dopamine receptor Rattus norvegicus 4500 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982977 103915197 CHEMBL38897 ZINC13454389 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000832 CN(C)CCCCCCCCCOc1ccc2oc(cc(=O)c2c1)-c1ccccc1 InChI=1S/C26H33NO3/c1-27(2)17-11-6-4-3-5-7-12-18-29-22-15-16-25-23(19-22)24(28)20-26(30-25)21-13-9-8-10-14-21/h8-10,13-16,19-20H,3-7,11-12,17-18H2,1-2H3 FWYUTSUWWZVOGD-UHFFFAOYSA-N 50000611 6-(9-Dimethylamino-nonyloxy)-2-phenyl-chromen-4-one::CHEMBL35828 D(2) dopamine receptor Rattus norvegicus 2200 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000611&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982956 103915159 CHEMBL35828 ZINC13454307 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000839 O=c1[nH]c2ccccc2n1C1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C33H35N3O4/c37-30-23-32(24-10-4-3-5-11-24)40-31-15-14-26(22-27(30)31)39-21-9-2-1-8-18-35-19-16-25(17-20-35)36-29-13-7-6-12-28(29)34-33(36)38/h3-7,10-15,22-23,25H,1-2,8-9,16-21H2,(H,34,38) VQTYANOITYVNNB-UHFFFAOYSA-N 50000632 1-{1-[6-(4-Oxo-2-phenyl-4H-chromen-6-yloxy)-hexyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL288623 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000632&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982983 103915180 CHEMBL288623 ZINC29334608 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000840 OCCC1CN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CCN1 InChI=1S/C27H34N2O4/c30-16-12-22-20-29(15-13-28-22)14-6-1-2-7-17-32-23-10-11-26-24(18-23)25(31)19-27(33-26)21-8-4-3-5-9-21/h3-5,8-11,18-19,22,28,30H,1-2,6-7,12-17,20H2 AMGPQKPUEYAJPL-UHFFFAOYSA-N 50000617 6-{6-[3-(2-Hydroxy-ethyl)-piperazin-1-yl]-hexyloxy}-2-phenyl-chromen-4-one::CHEMBL291132 D(2) dopamine receptor Rattus norvegicus 8300 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285320 103915165 CHEMBL291132 ZINC29321663 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000842 OC1CCN(CCCCOc2ccc3c(c2)oc(cc3=O)-c2ccccc2)CC1 InChI=1S/C24H27NO4/c26-19-10-13-25(14-11-19)12-4-5-15-28-20-8-9-21-22(27)17-23(29-24(21)16-20)18-6-2-1-3-7-18/h1-3,6-9,16-17,19,26H,4-5,10-15H2 XZTTUHFKZWBHFM-UHFFFAOYSA-N 50000579 7-[4-(4-Hydroxy-piperidin-1-yl)-butoxy]-2-phenyl-chromen-4-one::CHEMBL288933 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000579&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982992 103915127 CHEMBL288933 ZINC12356292 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000846 OC1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1 InChI=1S/C26H31NO4/c28-21-12-15-27(16-13-21)14-6-1-2-7-17-30-22-10-11-25-23(18-22)24(29)19-26(31-25)20-8-4-3-5-9-20/h3-5,8-11,18-19,21,28H,1-2,6-7,12-17H2 PUWFNZHXXZYRIS-UHFFFAOYSA-N 50000645 6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-phenyl-chromen-4-one::CHEMBL39445 D(2) dopamine receptor Rattus norvegicus 3700 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000645&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15230909 103915193 CHEMBL39445 ZINC13454318 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000849 OC1CCN(CCCCCCOc2cccc3oc(cc(=O)c23)-c2ccccc2)CC1 InChI=1S/C26H31NO4/c28-21-13-16-27(17-14-21)15-6-1-2-7-18-30-23-11-8-12-24-26(23)22(29)19-25(31-24)20-9-4-3-5-10-20/h3-5,8-12,19,21,28H,1-2,6-7,13-18H2 GPKJUEQFPWFURK-UHFFFAOYSA-N 50000647 5-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-phenyl-chromen-4-one::CHEMBL434593 D(2) dopamine receptor Rattus norvegicus 6100 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18959733 103915195 CHEMBL434593 ZINC12356393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000851 COc1cccc(c1)-c1cc(=O)c2cc(OCCCCCCN3CCC(O)CC3)ccc2o1 InChI=1S/C27H33NO5/c1-31-22-8-6-7-20(17-22)27-19-25(30)24-18-23(9-10-26(24)33-27)32-16-5-3-2-4-13-28-14-11-21(29)12-15-28/h6-10,17-19,21,29H,2-5,11-16H2,1H3 GNEPIPMEKRICGH-UHFFFAOYSA-N 50000591 6-[6-(4-Hydroxy-piperidin-1-yl)-hexyloxy]-2-(3-methoxy-phenyl)-chromen-4-one::CHEMBL39233 D(2) dopamine receptor Rattus norvegicus 9500 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983032 103915139 CHEMBL39233 ZINC13454427 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000854 O=c1cc(oc2ccc(OCCCCCCN3CCCC3)cc12)-c1ccccc1 InChI=1S/C25H29NO3/c27-23-19-25(20-10-4-3-5-11-20)29-24-13-12-21(18-22(23)24)28-17-9-2-1-6-14-26-15-7-8-16-26/h3-5,10-13,18-19H,1-2,6-9,14-17H2 YCIQIBGSBXHPCA-UHFFFAOYSA-N 50000584 2-Phenyl-6-(6-pyrrolidin-1-yl-hexyloxy)-chromen-4-one::CHEMBL40897 D(2) dopamine receptor Rattus norvegicus 2300 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000584&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14982964 103915132 CHEMBL40897 ZINC13454329 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000857 COc1cccc(c1)-c1cc(=O)c2cc(OCCCCCN3CCC(O)CC3)ccc2o1 InChI=1S/C26H31NO5/c1-30-21-7-5-6-19(16-21)26-18-24(29)23-17-22(8-9-25(23)32-26)31-15-4-2-3-12-27-13-10-20(28)11-14-27/h5-9,16-18,20,28H,2-4,10-15H2,1H3 POPCAXNXWKGYAL-UHFFFAOYSA-N 50000618 6-[5-(4-Hydroxy-piperidin-1-yl)-pentyloxy]-2-(3-methoxy-phenyl)-chromen-4-one::CHEMBL37410 D(2) dopamine receptor Rattus norvegicus 6200 ChEMBL 10.1021/jm00087a005 10.7270/Q2XG9Q38 1315869 Erickson, RH; Natalie, KJ; Bock, W; Lu, Z; Farzin, F; Sherrill, RG; Meloni, DJ; Patch, RJ; Rzesotarski, WJ; Clifton, J Nova Pharmaceutical Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14983031 103915166 CHEMBL37410 ZINC13454424 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000089 CN(CCN1CCCCCC1)CCc1ccc(Cl)c(Cl)c1 InChI=1S/C17H26Cl2N2/c1-20(12-13-21-9-4-2-3-5-10-21)11-8-15-6-7-16(18)17(19)14-15/h6-7,14H,2-5,8-13H2,1H3 UPBDZILZTPVMPX-UHFFFAOYSA-N 50000066 (2-Azepan-1-yl-ethyl)-[2-(3,4-dichloro-phenyl)-ethyl]-methyl-amine::CHEMBL356688 D(2) dopamine receptor Rattus norvegicus 6752.0 ChEMBL 10.1021/jm00079a004 10.7270/Q2BP01RW 1310114 de Costa, BR; Radesca, L; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000066&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5026275 103914764 CHEMBL356688 ZINC22448836 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000092 CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3 ASGIQUHBAVIOTI-UHFFFAOYSA-N 50000069 CHEMBL20377::[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-ethyl)-amine D(2) dopamine receptor Rattus norvegicus 1112 ChEMBL 10.1021/jm00079a004 10.7270/Q2BP01RW 1310114 de Costa, BR; Radesca, L; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000069&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126388 103914767 CHEMBL20377 ZINC22441678 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000100 CN(CCN1CCCCC1)CCc1ccc(Cl)c(Cl)c1 InChI=1S/C16H24Cl2N2/c1-19(11-12-20-8-3-2-4-9-20)10-7-14-5-6-15(17)16(18)13-14/h5-6,13H,2-4,7-12H2,1H3 DIQGETYKBHZBFV-UHFFFAOYSA-N 50000068 CHEMBL142700::[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-piperidin-1-yl-ethyl)-amine D(2) dopamine receptor Rattus norvegicus 1209 ChEMBL 10.1021/jm00079a004 10.7270/Q2BP01RW 1310114 de Costa, BR; Radesca, L; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000068&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9883360 103914766 CHEMBL142700 ZINC22924867 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000102 C[C@@H](CN1CCCC1)N(C)CCc1ccc(Cl)c(Cl)c1 InChI=1S/C16H24Cl2N2/c1-13(12-20-8-3-4-9-20)19(2)10-7-14-5-6-15(17)16(18)11-14/h5-6,11,13H,3-4,7-10,12H2,1-2H3/t13-/m0/s1 DBYCCKZCPWSDEM-ZDUSSCGKSA-N 50000067 CHEMBL347514::[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(1-methyl-2-pyrrolidin-1-yl-ethyl)-amine D(2) dopamine receptor Rattus norvegicus 11235 ChEMBL 10.1021/jm00079a004 10.7270/Q2BP01RW 1310114 de Costa, BR; Radesca, L; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15113312 103914765 CHEMBL347514 ZINC22924849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000105 CCN(CC)CCN(C)CCc1ccc(Cl)c(Cl)c1 InChI=1S/C15H24Cl2N2/c1-4-19(5-2)11-10-18(3)9-8-13-6-7-14(16)15(17)12-13/h6-7,12H,4-5,8-11H2,1-3H3 ZYPGNXDQORXUEH-UHFFFAOYSA-N 50000070 CHEMBL143178::N-[2-(3,4-Dichloro-phenyl)-ethyl]-N',N'-diethyl-N-methyl-ethane-1,2-diamine D(2) dopamine receptor Rattus norvegicus 3006 ChEMBL 10.1021/jm00079a004 10.7270/Q2BP01RW 1310114 de Costa, BR; Radesca, L; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000070&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15113308 103914768 CHEMBL143178 ZINC22924829 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000113 CN(CCN1CCCC1)CCc1cccc(Cl)c1 InChI=1S/C15H23ClN2/c1-17(11-12-18-8-2-3-9-18)10-7-14-5-4-6-15(16)13-14/h4-6,13H,2-3,7-12H2,1H3 QVJINWATNLFUKY-UHFFFAOYSA-N 50000074 CHEMBL142596::[2-(3-Chloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-ethyl)-amine D(2) dopamine receptor Rattus norvegicus 6497 ChEMBL 10.1021/jm00079a004 10.7270/Q2BP01RW 1310114 de Costa, BR; Radesca, L; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000074&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15113306 103914772 CHEMBL142596 ZINC22778717 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000118 CCN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 InChI=1S/C16H24Cl2N2/c1-2-19(11-12-20-8-3-4-9-20)10-7-14-5-6-15(17)16(18)13-14/h5-6,13H,2-4,7-12H2,1H3 NMEAEGORKFOIDR-UHFFFAOYSA-N 50000065 CHEMBL141501::[2-(3,4-Dichloro-phenyl)-ethyl]-ethyl-(2-pyrrolidin-1-yl-ethyl)-amine D(2) dopamine receptor Rattus norvegicus 1665 ChEMBL 10.1021/jm00079a004 10.7270/Q2BP01RW 1310114 de Costa, BR; Radesca, L; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9796923 103914763 CHEMBL141501 ZINC22454093 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50000119 CN(CCN1CCCC1)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C14H20Cl2N2/c1-17(8-9-18-6-2-3-7-18)11-12-4-5-13(15)14(16)10-12/h4-5,10H,2-3,6-9,11H2,1H3 FVDIBFWPKYGJJP-UHFFFAOYSA-N 50000078 (3,4-Dichloro-benzyl)-methyl-(2-pyrrolidin-1-yl-ethyl)-amine::CHEMBL143089 D(2) dopamine receptor Rattus norvegicus 1301 ChEMBL 10.1021/jm00079a004 10.7270/Q2BP01RW 1310114 de Costa, BR; Radesca, L; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000078&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15113313 103914776 CHEMBL143089 ZINC22778702 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002892 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(cc12)C(F)(F)F InChI=1S/C25H26F4N4O/c26-19-2-4-20(5-3-19)33-16-22(21-6-1-18(15-23(21)33)25(27,28)29)17-7-10-31(11-8-17)13-14-32-12-9-30-24(32)34/h1-6,15-17H,7-14H2,(H,30,34) OIEXLUYLHWCBJN-UHFFFAOYSA-N 50001771 1-(2-{4-[1-(4-Fluoro-phenyl)-6-trifluoromethyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL341669 D(2) dopamine receptor Rattus norvegicus 260 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11754649 103916144 CHEMBL341669 ZINC13731165 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002901 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(Cl)cc3)c3cc(C)ccc23)C1=O InChI=1S/C28H35ClN4O/c1-20(2)32-17-16-31(28(32)34)15-14-30-12-10-22(11-13-30)26-19-33(24-7-5-23(29)6-8-24)27-18-21(3)4-9-25(26)27/h4-9,18-20,22H,10-17H2,1-3H3 QMJKMWYSEUGRLA-UHFFFAOYSA-N 50001780 1-(2-{4-[1-(4-Chloro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL144165 D(2) dopamine receptor Rattus norvegicus 620 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001780&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10073825 103916153 CHEMBL144165 ZINC13731180 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002905 CC(C)NC(=O)NCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(C)ccc12 InChI=1S/C26H33FN4O/c1-18(2)29-26(32)28-12-15-30-13-10-20(11-14-30)24-17-31(22-7-5-21(27)6-8-22)25-16-19(3)4-9-23(24)25/h4-9,16-18,20H,10-15H2,1-3H3,(H2,28,29,32) VINVVWQQTYVRCW-UHFFFAOYSA-N 50001783 1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-urea::CHEMBL144951 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001783&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10365753 103916156 CHEMBL144951 ZINC13731213 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002906 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3cccc(c3)C(F)(F)F)c3cc(C)ccc23)C1=O InChI=1S/C29H35F3N4O/c1-20(2)35-16-15-34(28(35)37)14-13-33-11-9-22(10-12-33)26-19-36(27-17-21(3)7-8-25(26)27)24-6-4-5-23(18-24)29(30,31)32/h4-8,17-20,22H,9-16H2,1-3H3 KHMNDCKIIWBMLG-UHFFFAOYSA-N 50001777 1-Isopropyl-3-(2-{4-[6-methyl-1-(3-trifluoromethyl-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL356320 D(2) dopamine receptor Rattus norvegicus 3200 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10097929 103916150 CHEMBL356320 ZINC13731193 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002907 CC(C)NC(=O)N(C)CCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 InChI=1S/C26H32ClFN4O/c1-18(2)29-26(33)30(3)14-15-31-12-10-19(11-13-31)24-17-32(22-7-5-21(28)6-8-22)25-16-20(27)4-9-23(24)25/h4-9,16-19H,10-15H2,1-3H3,(H,29,33) OOQIOHUDMXBFGA-UHFFFAOYSA-N 50001785 1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-1-methyl-urea::CHEMBL144252 D(2) dopamine receptor Rattus norvegicus 74 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10322519 103916158 CHEMBL144252 ZINC13731205 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002910 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3cccc(F)c3)c3cc(C)ccc23)C1=O InChI=1S/C28H35FN4O/c1-20(2)32-16-15-31(28(32)34)14-13-30-11-9-22(10-12-30)26-19-33(24-6-4-5-23(29)18-24)27-17-21(3)7-8-25(26)27/h4-8,17-20,22H,9-16H2,1-3H3 KVWQLRMPAWIIEC-UHFFFAOYSA-N 50001788 1-(2-{4-[1-(3-Fluoro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL358994 D(2) dopamine receptor Rattus norvegicus 3200 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001788&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10344317 103916161 CHEMBL358994 ZINC13731190 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002914 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3F)c3cc(C)ccc23)C1=O InChI=1S/C28H35FN4O/c1-20(2)32-17-16-31(28(32)34)15-14-30-12-10-22(11-13-30)24-19-33(26-7-5-4-6-25(26)29)27-18-21(3)8-9-23(24)27/h4-9,18-20,22H,10-17H2,1-3H3 YVFUGTZUCVMFPR-UHFFFAOYSA-N 50001781 1-(2-{4-[1-(2-Fluoro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL357186 D(2) dopamine receptor Rattus norvegicus 730 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001781&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10389629 103916154 CHEMBL357186 ZINC13731187 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002915 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(F)cc12 InChI=1S/C24H26F2N4O/c25-18-1-4-20(5-2-18)30-16-22(21-6-3-19(26)15-23(21)30)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) KQKWCYWIRKGLKQ-UHFFFAOYSA-N 50001790 1-(2-{4-[6-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL344276 D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10365032 103916163 CHEMBL344276 ZINC13731171 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002916 CNC(=O)N(C)CCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 InChI=1S/C24H28ClFN4O/c1-27-24(31)28(2)13-14-29-11-9-17(10-12-29)22-16-30(20-6-4-19(26)5-7-20)23-15-18(25)3-8-21(22)23/h3-8,15-17H,9-14H2,1-2H3,(H,27,31) RGLSIOAWUHXTFV-UHFFFAOYSA-N 50001791 1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-1,3-dimethyl-urea::CHEMBL144457 D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10026395 103916164 CHEMBL144457 ZINC13731202 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002927 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-21-22(16-30(23(21)15-18)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) KAVXLKNTCZXGHC-UHFFFAOYSA-N 50001772 1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL423009 D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001772&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9889487 103916145 CHEMBL423009 ZINC13731159 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002930 CC(C)c1ccc2c(cn(-c3ccc(F)cc3)c2c1)C1CCN(CCN2CCNC2=O)CC1 InChI=1S/C27H33FN4O/c1-19(2)21-3-8-24-25(18-32(26(24)17-21)23-6-4-22(28)5-7-23)20-9-12-30(13-10-20)15-16-31-14-11-29-27(31)33/h3-8,17-20H,9-16H2,1-2H3,(H,29,33) ZQUAUCQTMBQTQA-UHFFFAOYSA-N 50001773 1-(2-{4-[1-(4-Fluoro-phenyl)-6-isopropyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL143782 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001773&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10003806 103916146 CHEMBL143782 ZINC13731177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002931 Cc1ccc2c(cn(-c3ccc(F)cc3)c2c1)C1CCN(CCN2CCNC2=O)CC1 InChI=1S/C25H29FN4O/c1-18-2-7-22-23(17-30(24(22)16-18)21-5-3-20(26)4-6-21)19-8-11-28(12-9-19)14-15-29-13-10-27-25(29)31/h2-7,16-17,19H,8-15H2,1H3,(H,27,31) HTLQTFJVKLZPQC-UHFFFAOYSA-N 50001796 1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL144086 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742887 103916169 CHEMBL144086 ZINC13731156 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002932 CN(C)C(=O)NCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 InChI=1S/C24H28ClFN4O/c1-28(2)24(31)27-11-14-29-12-9-17(10-13-29)22-16-30(20-6-4-19(26)5-7-20)23-15-18(25)3-8-21(22)23/h3-8,15-17H,9-14H2,1-2H3,(H,27,31) MPFZVQLLBTWGHH-UHFFFAOYSA-N 50001784 3-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-1,1-dimethyl-urea::CHEMBL422480 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001784&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10321160 103916157 CHEMBL422480 ZINC13731208 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002934 CC(C)N1CCN(CCN2CCC(CC2)c2c[nH]c3cc(C)ccc23)C1=O InChI=1S/C22H32N4O/c1-16(2)26-13-12-25(22(26)27)11-10-24-8-6-18(7-9-24)20-15-23-21-14-17(3)4-5-19(20)21/h4-5,14-16,18,23H,6-13H2,1-3H3 QGVAEWBRFSNZBU-UHFFFAOYSA-N 50001793 1-Isopropyl-3-{2-[4-(6-methyl-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-imidazolidin-2-one::CHEMBL145460 D(2) dopamine receptor Rattus norvegicus 590 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001793&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10361700 103916166 CHEMBL145460 ZINC13731216 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002937 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(F)ccc23)C1=O InChI=1S/C27H32F2N4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)25-18-33(23-6-3-21(28)4-7-23)26-17-22(29)5-8-24(25)26/h3-8,17-20H,9-16H2,1-2H3 APNZRLLPQMBJPZ-UHFFFAOYSA-N 50001789 1-(2-{4-[6-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL359046 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001789&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10457262 103916162 CHEMBL359046 ZINC13731168 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002938 CN(C)C(=O)NCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2cc(C)ccc12 InChI=1S/C25H31FN4O/c1-18-4-9-22-23(17-30(24(22)16-18)21-7-5-20(26)6-8-21)19-10-13-29(14-11-19)15-12-27-25(31)28(2)3/h4-9,16-17,19H,10-15H2,1-3H3,(H,27,31) QEVSWQMOAUIMSD-UHFFFAOYSA-N 50001787 3-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-1,1-dimethyl-urea::CHEMBL342104 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001787&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025272 103916160 CHEMBL342104 ZINC13731211 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002942 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3)c3cc(Cl)ccc23)C1=O InChI=1S/C27H33ClN4O/c1-20(2)31-17-16-30(27(31)33)15-14-29-12-10-21(11-13-29)25-19-32(23-6-4-3-5-7-23)26-18-22(28)8-9-24(25)26/h3-9,18-21H,10-17H2,1-2H3 DRSRXSCHUHUFBD-UHFFFAOYSA-N 50001798 1-{2-[4-(6-Chloro-1-phenyl-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-3-isopropyl-imidazolidin-2-one::CHEMBL145763 D(2) dopamine receptor Rattus norvegicus 290 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001798&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10322234 103916171 CHEMBL145763 ZINC13731196 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002944 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3)c3cc(C)ccc23)C1=O InChI=1S/C28H36N4O/c1-21(2)31-18-17-30(28(31)33)16-15-29-13-11-23(12-14-29)26-20-32(24-7-5-4-6-8-24)27-19-22(3)9-10-25(26)27/h4-10,19-21,23H,11-18H2,1-3H3 NVDGVHLBFYZKSO-UHFFFAOYSA-N 50001792 1-Isopropyl-3-{2-[4-(6-methyl-1-phenyl-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-imidazolidin-2-one::CHEMBL343899 D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11744188 103916165 CHEMBL343899 ZINC13731183 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002946 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccccc3F)c3cc(Cl)ccc23)C1=O InChI=1S/C27H32ClFN4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)23-18-33(25-6-4-3-5-24(25)29)26-17-21(28)7-8-22(23)26/h3-8,17-20H,9-16H2,1-2H3 PHKYJSDVXODLTC-UHFFFAOYSA-N 50001795 1-(2-{4-[6-Chloro-1-(2-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL145706 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001795&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10457974 103916168 CHEMBL145706 ZINC13731199 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005068 COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC(C1)N2Cc1ccccc1 InChI=1S/C22H26ClN3O2/c1-28-21-12-20(24)19(23)11-18(21)22(27)25-15-9-16-7-8-17(10-15)26(16)13-14-5-3-2-4-6-14/h2-6,11-12,15-17H,7-10,13,24H2,1H3,(H,25,27) BQHYHGXYIOWFJL-UHFFFAOYSA-N 50123807 4-Amino-N-(8-benzoyl-8-aza-bicyclo[3.2.1]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(8-benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-5-chloro-2-methoxy-benzamide::BRL-25594::CHEMBL164919 D(2) dopamine receptor Rattus norvegicus 0.280000 ChEMBL 10.1016/0960-894X(95)00115-A 10.7270/Q2R78FP7 Langlois, M; Yang, D; Bremont, B; Shen, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10069545 104016219 CHEMBL164919 ZINC12356281 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002947 Cc1c(C2=CCN(CCN3CCNC3=O)CC2)c2ccccc2n1-c1ccc(F)cc1 InChI=1S/C25H27FN4O/c1-18-24(19-10-13-28(14-11-19)16-17-29-15-12-27-25(29)31)22-4-2-3-5-23(22)30(18)21-8-6-20(26)7-9-21/h2-10H,11-17H2,1H3,(H,27,31) QNKNONFOUXSKRI-UHFFFAOYSA-N 50001776 1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL422840 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001776&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10409784 103916149 CHEMBL422840 ZINC13731222 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002955 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(ccc23)C(F)(F)F)C1=O InChI=1S/C28H32F4N4O/c1-19(2)35-16-15-34(27(35)37)14-13-33-11-9-20(10-12-33)25-18-36(23-6-4-22(29)5-7-23)26-17-21(28(30,31)32)3-8-24(25)26/h3-8,17-20H,9-16H2,1-2H3 GAIGLAXWAMZODA-UHFFFAOYSA-N 50001799 1-(2-{4-[1-(4-Fluoro-phenyl)-6-trifluoromethyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL144184 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10075243 103916172 CHEMBL144184 ZINC13731162 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002956 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H27FN4O/c25-19-5-7-20(8-6-19)29-17-22(21-3-1-2-4-23(21)29)18-9-12-27(13-10-18)15-16-28-14-11-26-24(28)30/h1-8,17-18H,9-16H2,(H,26,30) QPOLRENOYJQNEP-UHFFFAOYSA-N 50001778 (Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL12780 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742071 103916151 CHEMBL12780 ZINC13452450 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002960 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(ccc23)C(C)C)C1=O InChI=1S/C30H39FN4O/c1-21(2)24-5-10-27-28(20-35(29(27)19-24)26-8-6-25(31)7-9-26)23-11-13-32(14-12-23)15-16-33-17-18-34(22(3)4)30(33)36/h5-10,19-23H,11-18H2,1-4H3 KSBIMIXXUPKBLA-UHFFFAOYSA-N 50001779 1-(2-{4-[1-(4-Fluoro-phenyl)-6-isopropyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL142908 D(2) dopamine receptor Rattus norvegicus 2000 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001779&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10323306 103916152 CHEMBL142908 ZINC13731174 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002962 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(Cl)ccc23)C1=O InChI=1S/C27H32ClFN4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)25-18-33(23-6-4-22(29)5-7-23)26-17-21(28)3-8-24(25)26/h3-8,17-20H,9-16H2,1-2H3 NIMNILHFXBBMBV-UHFFFAOYSA-N 50001782 (Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL331545 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9826570 103916155 CHEMBL331545 ZINC00598062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002964 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(C)ccc23)C1=O InChI=1S/C28H35FN4O/c1-20(2)32-17-16-31(28(32)34)15-14-30-12-10-22(11-13-30)26-19-33(24-7-5-23(29)6-8-24)27-18-21(3)4-9-25(26)27/h4-9,18-20,22H,10-17H2,1-3H3 KGASELUWIGUZKN-UHFFFAOYSA-N 50001794 1-(2-{4-[1-(4-Fluoro-phenyl)-6-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL144325 D(2) dopamine receptor Rattus norvegicus 190 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001794&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10004551 103916167 CHEMBL144325 ZINC00604377 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002965 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002967 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002974 CC(C)N1CCN(CCN2CCC(CC2)c2c[nH]c3cc(Cl)ccc23)C1=O InChI=1S/C21H29ClN4O/c1-15(2)26-12-11-25(21(26)27)10-9-24-7-5-16(6-8-24)19-14-23-20-13-17(22)3-4-18(19)20/h3-4,13-16,23H,5-12H2,1-2H3 LSMDWDOOOHZEDU-UHFFFAOYSA-N 50001774 1-{2-[4-(6-Chloro-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-3-isopropyl-imidazolidin-2-one::CHEMBL357178 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11741028 103916147 CHEMBL357178 ZINC13731219 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002976 Cc1c(C2CCN(CCN3CCNC3=O)CC2)c2ccccc2n1-c1ccc(F)cc1 InChI=1S/C25H29FN4O/c1-18-24(19-10-13-28(14-11-19)16-17-29-15-12-27-25(29)31)22-4-2-3-5-23(22)30(18)21-8-6-20(26)7-9-21/h2-9,19H,10-17H2,1H3,(H,27,31) OOHASZCAJGUYFP-UHFFFAOYSA-N 50001797 1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL423024 D(2) dopamine receptor Rattus norvegicus 380 ChEMBL 10.1021/jm00104a006 10.7270/Q2G73CNK 1336053 Perregaard, J; Andersen, K; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10387431 103916170 CHEMBL423024 ZINC13731225 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002978 CN1CCC(CC1)n1cc(-c2ccc(F)cc2)c2cc(C)ccc12 InChI=1S/C21H23FN2/c1-15-3-8-21-19(13-15)20(16-4-6-17(22)7-5-16)14-24(21)18-9-11-23(2)12-10-18/h3-8,13-14,18H,9-12H2,1-2H3 UJOWBALLYUQQQK-UHFFFAOYSA-N 50001801 3-(4-Fluoro-phenyl)-5-methyl-1-(1-methyl-piperidin-4-yl)-1H-indole::CHEMBL344335 D(2) dopamine receptor Rattus norvegicus 540 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10426286 103916174 CHEMBL344335 ZINC13731247 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002980 Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H27FN4O/c25-19-7-5-18(6-8-19)22-17-29(23-4-2-1-3-21(22)23)20-9-12-27(13-10-20)15-16-28-14-11-26-24(28)30/h1-8,17,20H,9-16H2,(H,26,30) TWERGYLJSRWLJS-UHFFFAOYSA-N 50001802 1-(2-{4-[3-(4-Fluoro-phenyl)-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL359031 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10409070 103916175 CHEMBL359031 ZINC13731231 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002983 Cc1cccc2c(cn(C3=CCN(CCN4CCNC4=O)CC3)c12)-c1ccc(F)cc1 InChI=1S/C25H27FN4O/c1-18-3-2-4-22-23(19-5-7-20(26)8-6-19)17-30(24(18)22)21-9-12-28(13-10-21)15-16-29-14-11-27-25(29)31/h2-9,17H,10-16H2,1H3,(H,27,31) PQNSPAOOWUBCML-UHFFFAOYSA-N 50001805 1-(2-{4-[3-(4-Fluoro-phenyl)-7-methyl-indol-1-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL141667 D(2) dopamine receptor Rattus norvegicus 530 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10341964 103916178 CHEMBL141667 ZINC13731256 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002985 Cc1c(-c2ccc(F)cc2)c2cc(C)ccc2n1C1=CCN(CCN2CCNC2=O)CC1 InChI=1S/C26H29FN4O/c1-18-3-8-24-23(17-18)25(20-4-6-21(27)7-5-20)19(2)31(24)22-9-12-29(13-10-22)15-16-30-14-11-28-26(30)32/h3-9,17H,10-16H2,1-2H3,(H,28,32) REEDEDPSJLIHLC-UHFFFAOYSA-N 50001807 1-(2-{4-[3-(4-Fluoro-phenyl)-2,5-dimethyl-indol-1-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL143617 D(2) dopamine receptor Rattus norvegicus 6300 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10048445 103916180 CHEMBL143617 ZINC27524528 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002986 CC(C)N1CCN(CCN2CCC(CC2)n2cc(-c3ccc(F)cc3)c3cc(C)ccc23)C1=O InChI=1S/C28H35FN4O/c1-20(2)32-17-16-31(28(32)34)15-14-30-12-10-24(11-13-30)33-19-26(22-5-7-23(29)8-6-22)25-18-21(3)4-9-27(25)33/h4-9,18-20,24H,10-17H2,1-3H3 AOVJKFZMDSJQDY-UHFFFAOYSA-N 50001808 1-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL145712 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9956013 103916181 CHEMBL145712 ZINC00604452 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002987 Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-3-6-21-22(17-1-4-19(26)5-2-17)16-30(23(21)15-18)20-7-10-28(11-8-20)13-14-29-12-9-27-24(29)31/h1-6,15-16,20H,7-14H2,(H,27,31) IXWMONQJSSRIPH-UHFFFAOYSA-N 50001806 1-(2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL422130 D(2) dopamine receptor Rattus norvegicus 37 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10094822 103916179 CHEMBL422130 ZINC13731228 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002998 Cc1cccc2c(cn(C3CCN(CCN4CCNC4=O)CC3)c12)-c1ccc(F)cc1 InChI=1S/C25H29FN4O/c1-18-3-2-4-22-23(19-5-7-20(26)8-6-19)17-30(24(18)22)21-9-12-28(13-10-21)15-16-29-14-11-27-25(29)31/h2-8,17,21H,9-16H2,1H3,(H,27,31) BTXNBVXZBBDLMA-UHFFFAOYSA-N 50001814 1-(2-{4-[3-(4-Fluoro-phenyl)-7-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL144901 D(2) dopamine receptor Rattus norvegicus 370 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10047772 103916187 CHEMBL144901 ZINC13731245 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003001 Cc1ccc2n(cc(-c3ccc(F)cc3)c2c1)C1=CCN(CCN2CCNC2=O)CC1 InChI=1S/C25H27FN4O/c1-18-2-7-24-22(16-18)23(19-3-5-20(26)6-4-19)17-30(24)21-8-11-28(12-9-21)14-15-29-13-10-27-25(29)31/h2-8,16-17H,9-15H2,1H3,(H,27,31) NCIFROQGTVGVHM-UHFFFAOYSA-N 50001811 1-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL343034 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9931837 103916184 CHEMBL343034 ZINC13731253 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003002 CN1CCC(CC1)n1c(C)c(-c2ccc(F)cc2)c2cc(C)ccc12 InChI=1S/C22H25FN2/c1-15-4-9-21-20(14-15)22(17-5-7-18(23)8-6-17)16(2)25(21)19-10-12-24(3)13-11-19/h4-9,14,19H,10-13H2,1-3H3 JHXVZNYMJMMPEI-UHFFFAOYSA-N 50001809 3-(4-Fluoro-phenyl)-2,5-dimethyl-1-(1-methyl-piperidin-4-yl)-1H-indole::CHEMBL144362 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10427137 103916182 CHEMBL144362 ZINC00015635 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003004 Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C24H26ClFN4O/c25-18-3-6-23-21(15-18)22(17-1-4-19(26)5-2-17)16-30(23)20-7-10-28(11-8-20)13-14-29-12-9-27-24(29)31/h1-6,15-16,20H,7-14H2,(H,27,31) NPMRTXFAPRHTBW-UHFFFAOYSA-N 50001816 1-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL357019 D(2) dopamine receptor Rattus norvegicus 410 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10003405 103916189 CHEMBL357019 ZINC13731237 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003006 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(Cl)ccc23)C1=O InChI=1S/C27H32ClFN4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)25-18-33(23-6-4-22(29)5-7-23)26-17-21(28)3-8-24(25)26/h3-8,17-20H,9-16H2,1-2H3 NIMNILHFXBBMBV-UHFFFAOYSA-N 50001782 (Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL331545 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9826570 103916155 CHEMBL331545 ZINC00598062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003008 Cc1ccc2n(cc(-c3ccc(F)cc3)c2c1)C1CCN(CCN2CCNC2=O)CC1 InChI=1S/C25H29FN4O/c1-18-2-7-24-22(16-18)23(19-3-5-20(26)6-4-19)17-30(24)21-8-11-28(12-9-21)14-15-29-13-10-27-25(29)31/h2-7,16-17,21H,8-15H2,1H3,(H,27,31) LZSPHUKWGNMGSE-UHFFFAOYSA-N 50001803 1-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL144767 D(2) dopamine receptor Rattus norvegicus 920 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10364835 103916176 CHEMBL144767 ZINC00604451 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003009 CN(C)C(=O)NCCN1CCC(CC1)n1cc(-c2ccc(F)cc2)c2cc(C)ccc12 InChI=1S/C25H31FN4O/c1-18-4-9-24-22(16-18)23(19-5-7-20(26)8-6-19)17-30(24)21-10-13-29(14-11-21)15-12-27-25(31)28(2)3/h4-9,16-17,21H,10-15H2,1-3H3,(H,27,31) BYYHVUKATBOAAS-UHFFFAOYSA-N 50001817 3-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-1,1-dimethyl-urea::CHEMBL144710 D(2) dopamine receptor Rattus norvegicus 260 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10093723 103916190 CHEMBL144710 ZINC13731250 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003012 Cc1c(-c2ccc(F)cc2)c2cc(C)ccc2n1C1CCN(CCN2CCNC2=O)CC1 InChI=1S/C26H31FN4O/c1-18-3-8-24-23(17-18)25(20-4-6-21(27)7-5-20)19(2)31(24)22-9-12-29(13-10-22)15-16-30-14-11-28-26(30)32/h3-8,17,22H,9-16H2,1-2H3,(H,28,32) OUEICZGYFSHCOY-UHFFFAOYSA-N 50001800 1-(2-{4-[3-(4-Fluoro-phenyl)-2,5-dimethyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL343444 D(2) dopamine receptor Rattus norvegicus 6900 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9845791 103916173 CHEMBL343444 ZINC00604455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003014 CNC(=O)N(C)CCN1CCC(CC1)n1cc(-c2ccc(F)cc2)c2cc(C)ccc12 InChI=1S/C25H31FN4O/c1-18-4-9-24-22(16-18)23(19-5-7-20(26)8-6-19)17-30(24)21-10-12-29(13-11-21)15-14-28(3)25(31)27-2/h4-9,16-17,21H,10-15H2,1-3H3,(H,27,31) AVFXKVJXVWBTJZ-UHFFFAOYSA-N 50001813 1-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-1,3-dimethyl-urea::CHEMBL356799 D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10047887 103916186 CHEMBL356799 ZINC00604456 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003021 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003027 Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccc(cc12)C(F)(F)F InChI=1S/C25H26F4N4O/c26-19-4-1-17(2-5-19)22-16-33(23-6-3-18(15-21(22)23)25(27,28)29)20-7-10-31(11-8-20)13-14-32-12-9-30-24(32)34/h1-6,15-16,20H,7-14H2,(H,30,34) PNJBDZLOVISXIH-UHFFFAOYSA-N 50001815 1-(2-{4-[3-(4-Fluoro-phenyl)-5-trifluoromethyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL355917 D(2) dopamine receptor Rattus norvegicus 2500 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10254306 103916188 CHEMBL355917 ZINC13731240 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003031 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003032 Cc1cccc2n(cc(-c3ccc(F)cc3)c12)C1CCN(CCN2CCNC2=O)CC1 InChI=1S/C25H29FN4O/c1-18-3-2-4-23-24(18)22(19-5-7-20(26)8-6-19)17-30(23)21-9-12-28(13-10-21)15-16-29-14-11-27-25(29)31/h2-8,17,21H,9-16H2,1H3,(H,27,31) UFCWWRYYWMLFPE-UHFFFAOYSA-N 50001804 1-(2-{4-[3-(4-Fluoro-phenyl)-4-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL342730 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001804&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10409893 103916177 CHEMBL342730 ZINC13731242 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003034 Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccc(F)cc12 InChI=1S/C24H26F2N4O/c25-18-3-1-17(2-4-18)22-16-30(23-6-5-19(26)15-21(22)23)20-7-10-28(11-8-20)13-14-29-12-9-27-24(29)31/h1-6,15-16,20H,7-14H2,(H,27,31) FKZJBKNKELKMSE-UHFFFAOYSA-N 50001812 1-(2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL144318 D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001812&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10477439 103916185 CHEMBL144318 ZINC13731234 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003036 CN1CCN(CC1)n1cc(-c2ccc(F)cc2)c2cc(C)ccc12 InChI=1S/C20H22FN3/c1-15-3-8-20-18(13-15)19(16-4-6-17(21)7-5-16)14-24(20)23-11-9-22(2)10-12-23/h3-8,13-14H,9-12H2,1-2H3 DEZIQNCPVPFWEE-UHFFFAOYSA-N 50001810 3-(4-Fluoro-phenyl)-5-methyl-1-(4-methyl-piperazin-1-yl)-1H-indole::CHEMBL141721 D(2) dopamine receptor Rattus norvegicus 3900 ChEMBL 10.1021/jm00104a007 10.7270/Q2BK1B8P 1336054 Andersen, K; Perregaard, J; Arnt, J; Nielsen, JB; Begtrup, M H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10245637 103916183 CHEMBL141721 ZINC13731259 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005279 CN1CCc2cccc(O)c2CC1 InChI=1S/C11H15NO/c1-12-7-5-9-3-2-4-11(13)10(9)6-8-12/h2-4,13H,5-8H2,1H3 CFWMKBWIBFWFRU-UHFFFAOYSA-N 50003339 3-Methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-6-ol::CHEMBL129387 D(2) dopamine receptor Rattus norvegicus 15000 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10058069 103917312 CHEMBL129387 ZINC12355887 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005280 COc1cccc2CCN(C)CCc12 InChI=1S/C12H17NO/c1-13-8-6-10-4-3-5-12(14-2)11(10)7-9-13/h3-5H,6-9H2,1-2H3 MIPZIIZDMHWHQJ-UHFFFAOYSA-N 50003340 6-Methoxy-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL127959 D(2) dopamine receptor Rattus norvegicus 2300 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10397680 103917313 CHEMBL127959 ZINC13728512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005282 CCCN1CCc2c(Br)ccc(OC)c2CC1 InChI=1S/C14H20BrNO/c1-3-8-16-9-6-11-12(7-10-16)14(17-2)5-4-13(11)15/h4-5H,3,6-10H2,1-2H3 WPMMOWKJPCOCHT-UHFFFAOYSA-N 50003342 6-Bromo-9-methoxy-3-propyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL440340 D(2) dopamine receptor Rattus norvegicus 680 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15039833 103917315 CHEMBL440340 ZINC13728503 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005287 CCN1CCc2cccc(O)c2CC1 InChI=1S/C12H17NO/c1-2-13-8-6-10-4-3-5-12(14)11(10)7-9-13/h3-5,14H,2,6-9H2,1H3 HTCXSPINZBVTNI-UHFFFAOYSA-N 50003341 3-Ethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-6-ol::CHEMBL129249 D(2) dopamine receptor Rattus norvegicus 14000 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10261961 103917314 CHEMBL129249 ZINC13728518 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005288 CCCN1CCc2cccc(O)c2CC1 InChI=1S/C13H19NO/c1-2-8-14-9-6-11-4-3-5-13(15)12(11)7-10-14/h3-5,15H,2,6-10H2,1H3 HBPJBRCEAWPEIH-UHFFFAOYSA-N 50003346 3-Propyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-6-ol::CHEMBL127221 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10420494 103917319 CHEMBL127221 ZINC13728497 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005291 CCCCN1CCc2cccc(O)c2CC1 InChI=1S/C14H21NO/c1-2-3-9-15-10-7-12-5-4-6-14(16)13(12)8-11-15/h4-6,16H,2-3,7-11H2,1H3 LLOMAHVTVGHSNN-UHFFFAOYSA-N 50003343 3-Butyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-6-ol::CHEMBL132112 D(2) dopamine receptor Rattus norvegicus 12000 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10376148 103917316 CHEMBL132112 ZINC13728506 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005292 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 5800 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005294 CCCN1CCc2cccc(OC)c2CC1 InChI=1S/C14H21NO/c1-3-9-15-10-7-12-5-4-6-14(16-2)13(12)8-11-15/h4-6H,3,7-11H2,1-2H3 ATLRIVSFIOMEDL-UHFFFAOYSA-N 50003348 6-Methoxy-3-propyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL128722 D(2) dopamine receptor Rattus norvegicus 3600 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10420986 103917321 CHEMBL128722 ZINC13728500 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005296 CCN1CCc2cccc(OC)c2CC1 InChI=1S/C13H19NO/c1-3-14-9-7-11-5-4-6-13(15-2)12(11)8-10-14/h4-6H,3,7-10H2,1-2H3 CUQCQXGIZXDFAR-UHFFFAOYSA-N 50003347 3-Ethyl-6-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL339061 D(2) dopamine receptor Rattus norvegicus 2200 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10352916 103917320 CHEMBL339061 ZINC13728515 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005297 CCCN1CCc2ccc(O)cc2CC1 InChI=1S/C13H19NO/c1-2-7-14-8-5-11-3-4-13(15)10-12(11)6-9-14/h3-4,10,15H,2,5-9H2,1H3 RZURICYHBFWBJM-UHFFFAOYSA-N 50003344 3-Propyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL129676 D(2) dopamine receptor Rattus norvegicus 10000 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10013191 103917317 CHEMBL129676 ZINC13728509 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50005300 COc1cccc2CCN(CC3CC3)CCc12 InChI=1S/C15H21NO/c1-17-15-4-2-3-13-7-9-16(10-8-14(13)15)11-12-5-6-12/h2-4,12H,5-11H2,1H3 KRJGVDZHHOXNSY-UHFFFAOYSA-N 50003345 3-Cyclopropylmethyl-6-methoxy-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL129293 D(2) dopamine receptor Rattus norvegicus 7600 ChEMBL 10.1021/jm00100a002 10.7270/Q2QN65QF 1433207 Wikstrom, H; Andersson, B; Elebring, T; Lagerkvist, S; Hallnemo, G; Pettersson, I; Jovall, PA; Svensson, K; Ekman, A; Carlsson, A University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10036886 103917318 CHEMBL129293 ZINC12355904 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002144 C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1 MQHGACGPMGUHSJ-HXUWFJFHSA-N 50055724 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyridin-2-yl-piperazine::CHEMBL418937::PD-137789 D(2) dopamine receptor Rattus norvegicus 412 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10904165 103952206 CHEMBL418937 ZINC26575034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002153 C(CN1CCN(CC1)c1ccccn1)[C@@H]1CCC(=CC1)c1ccccc1 InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m0/s1 MQHGACGPMGUHSJ-FQEVSTJZSA-N 50281606 1-[2-((R)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyridin-2-yl-piperazine::CHEMBL348547::PD-137821 D(2) dopamine receptor Rattus norvegicus 545 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281606&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372627 104123280 CHEMBL348547 ZINC27715109 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002155 CN1CCC=C2[C@@H]1CCc1sc(N)nc21 InChI=1S/C11H15N3S/c1-14-6-2-3-7-8(14)4-5-9-10(7)13-11(12)15-9/h3,8H,2,4-6H2,1H3,(H2,12,13)/t8-/m0/s1 XFJSSDHKIXXJLM-QMMMGPOBSA-N 50279805 (S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-2-ylamine::CHEMBL348012 D(2) dopamine receptor Rattus norvegicus 2920 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44367326 104121509 CHEMBL348012 ZINC05140806 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50001103 CN1CCN(CC1)C1=Cn2cccc2Sc2ccccc12 InChI=1S/C17H19N3S/c1-18-9-11-19(12-10-18)15-13-20-8-4-7-17(20)21-16-6-3-2-5-14(15)16/h2-8,13H,9-12H2,1H3 JFLBTRDHDHTNGX-UHFFFAOYSA-N 50137976 9-(4-Methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL367045 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137976&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9796255 104028114 CHEMBL367045 ZINC28014373 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003430 CN1CCC(=CC1)c1cn(-c2ccc(F)cc2)c2ccccc12 InChI=1S/C20H19FN2/c1-22-12-10-15(11-13-22)19-14-23(17-8-6-16(21)7-9-17)20-5-3-2-4-18(19)20/h2-10,14H,11-13H2,1H3 QVTIYLFSBMCCJG-UHFFFAOYSA-N 50001989 1-(4-Fluoro-phenyl)-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL417614 D(2) dopamine receptor Rattus norvegicus 1.6 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001989&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006440 103916342 CHEMBL417614 ZINC13452410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003431 CN1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3ccc(Cl)cc23)C1=O InChI=1S/C25H28ClFN4O/c1-28-12-14-30(25(28)32)15-13-29-10-8-18(9-11-29)23-17-31(21-5-3-20(27)4-6-21)24-7-2-19(26)16-22(23)24/h2-7,16-18H,8-15H2,1H3 NPXVUDZHAJFOPS-UHFFFAOYSA-N 50001991 1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-methyl-imidazolidin-2-one::CHEMBL275496 D(2) dopamine receptor Rattus norvegicus 6.5 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001991&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006464 103916344 CHEMBL275496 ZINC13452509 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003433 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003435 Fc1ccc(cc1)-n1cc(C2=CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)C#N InChI=1S/C25H24FN5O/c26-20-2-4-21(5-3-20)31-17-23(22-15-18(16-27)1-6-24(22)31)19-7-10-29(11-8-19)13-14-30-12-9-28-25(30)32/h1-7,15,17H,8-14H2,(H,28,32) XIIDUDUKMUCPBP-UHFFFAOYSA-N 50001993 1-(4-Fluoro-phenyl)-3-{1-[2-(2-oxo-imidazolidin-1-yl)-ethyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1H-indole-5-carbonitrile::CHEMBL268970 D(2) dopamine receptor Rattus norvegicus 2.1 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006444 103916346 CHEMBL268970 ZINC13452436 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003436 OCCN1CCN(CC1)c1cn(-c2ccc(F)cc2)c2ccc(cc12)C(F)(F)F InChI=1S/C21H21F4N3O/c22-16-2-4-17(5-3-16)28-14-20(27-9-7-26(8-10-27)11-12-29)18-13-15(21(23,24)25)1-6-19(18)28/h1-6,13-14,29H,7-12H2 NCZRXRGIUPSHIH-UHFFFAOYSA-N 50001994 2-{4-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-indol-3-yl]-piperazin-1-yl}-ethanol::CHEMBL12843 D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3065056 103916347 CHEMBL12843 ZINC13452396 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003441 Fc1ccc(cc1)-n1cc(c2cc(Cl)ccc12)C1(CCN(CCN2CCNC2=O)CC1)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C38H33Cl2F2N5O/c39-25-1-11-35-31(21-25)33(23-46(35)29-7-3-27(41)4-8-29)38(13-16-44(17-14-38)19-20-45-18-15-43-37(45)48)34-24-47(30-9-5-28(42)6-10-30)36-12-2-26(40)22-32(34)36/h1-12,21-24H,13-20H2,(H,43,48) DHBZKQDTEBHPAI-UHFFFAOYSA-N 50001999 1-(2-{4,4-Bis-[5-chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL275547 D(2) dopamine receptor Rattus norvegicus 760 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001999&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006470 103916352 CHEMBL275547 ZINC49600164 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003442 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)C#N InChI=1S/C25H26FN5O/c26-20-2-4-21(5-3-20)31-17-23(22-15-18(16-27)1-6-24(22)31)19-7-10-29(11-8-19)13-14-30-12-9-28-25(30)32/h1-6,15,17,19H,7-14H2,(H,28,32) RHASQCTWMNDBBX-UHFFFAOYSA-N 50002000 1-(4-Fluoro-phenyl)-3-{1-[2-(2-oxo-imidazolidin-1-yl)-ethyl]-piperidin-4-yl}-1H-indole-5-carbonitrile::CHEMBL12453 D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002000&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11059092 103916353 CHEMBL12453 ZINC13452476 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003444 Fc1ccc(cc1)-n1cc(C2CCN(CCCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C25H28ClFN4O/c26-19-2-7-24-22(16-19)23(17-31(24)21-5-3-20(27)4-6-21)18-8-13-29(14-9-18)11-1-12-30-15-10-28-25(30)32/h2-7,16-18H,1,8-15H2,(H,28,32) CXAQDXCWRCDSDO-UHFFFAOYSA-N 50002004 1-(3-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-propyl)-imidazolidin-2-one::CHEMBL267549 D(2) dopamine receptor Rattus norvegicus 3.4 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002004&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006460 103916357 CHEMBL267549 ZINC13452489 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003445 Fc1ccc(cc1)-n1cc(C2CCN(CCCCCCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C28H34ClFN4O/c29-22-5-10-27-25(19-22)26(20-34(27)24-8-6-23(30)7-9-24)21-11-16-32(17-12-21)14-3-1-2-4-15-33-18-13-31-28(33)35/h5-10,19-21H,1-4,11-18H2,(H,31,35) ARCMZUUOXKBRHF-UHFFFAOYSA-N 50002005 1-(6-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-hexyl)-imidazolidin-2-one::CHEMBL13051 D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002005&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006463 103916358 CHEMBL13051 ZINC13452504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003446 Fc1ccc(cc1)-n1cc(C2=CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H24ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-7,15-16H,8-14H2,(H,27,31) PFOLMILRZUSKJO-UHFFFAOYSA-N 50002002 1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL12186 D(2) dopamine receptor Rattus norvegicus 2.3 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002002&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006442 103916355 CHEMBL12186 ZINC13452432 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003447 CS(=O)(=O)c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C25H29FN4O3S/c1-34(32,33)21-6-7-24-22(16-21)23(17-30(24)20-4-2-19(26)3-5-20)18-8-11-28(12-9-18)14-15-29-13-10-27-25(29)31/h2-7,16-18H,8-15H2,1H3,(H,27,31) WWUPTACXJJHODT-UHFFFAOYSA-N 50002003 1-(2-{4-[1-(4-Fluoro-phenyl)-5-methanesulfonyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL274176 D(2) dopamine receptor Rattus norvegicus 5.8 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002003&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9873473 103916356 CHEMBL274176 ZINC13452481 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003452 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCN(C3=O)c3ccccc3)CC2)c2cc(Cl)ccc12 InChI=1S/C30H30ClFN4O/c31-23-6-11-29-27(20-23)28(21-36(29)26-9-7-24(32)8-10-26)22-12-14-33(15-13-22)16-17-34-18-19-35(30(34)37)25-4-2-1-3-5-25/h1-11,20-22H,12-19H2 ZKSRUFVYVYEELI-UHFFFAOYSA-N 50002006 1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-phenyl-imidazolidin-2-one::CHEMBL12848 D(2) dopamine receptor Rattus norvegicus 92 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002006&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006467 103916359 CHEMBL12848 ZINC13452517 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003453 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H27FN4O/c25-19-5-7-20(8-6-19)29-17-22(21-3-1-2-4-23(21)29)18-9-12-27(13-10-18)15-16-28-14-11-26-24(28)30/h1-8,17-18H,9-16H2,(H,26,30) QPOLRENOYJQNEP-UHFFFAOYSA-N 50001778 (Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL12780 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742071 103916151 CHEMBL12780 ZINC13452450 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003454 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003457 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 7.5 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003458 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 410 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003459 Fc1ccc(cc1)-n1cc(C2CCNCC2)c2cc(Cl)ccc12 InChI=1S/C19H18ClFN2/c20-14-1-6-19-17(11-14)18(13-7-9-22-10-8-13)12-23(19)16-4-2-15(21)3-5-16/h1-6,11-13,22H,7-10H2 YCXCLZSLZGBCTA-UHFFFAOYSA-N 50002009 5-Chloro-1-(4-fluoro-phenyl)-3-piperidin-4-yl-1H-indole::CHEMBL273235 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002009&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9862272 103916362 CHEMBL273235 ZINC13452441 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003461 CN1CCC(=CC1)c1cn(-c2ccc(F)cc2)c2ccc(cc12)[N+]([O-])=O InChI=1S/C20H18FN3O2/c1-22-10-8-14(9-11-22)19-13-23(16-4-2-15(21)3-5-16)20-7-6-17(24(25)26)12-18(19)20/h2-8,12-13H,9-11H2,1H3 XMEYKENMGPBBQT-UHFFFAOYSA-N 50002011 1-(4-Fluoro-phenyl)-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-5-nitro-1H-indole::CHEMBL12648 D(2) dopamine receptor Rattus norvegicus 0.760000 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002011&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3065055 103916364 CHEMBL12648 ZINC13452426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003466 Fc1ccc(cc1)-n1cc(C2CCN(CCCCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C26H30ClFN4O/c27-20-3-8-25-23(17-20)24(18-32(25)22-6-4-21(28)5-7-22)19-9-14-30(15-10-19)12-1-2-13-31-16-11-29-26(31)33/h3-8,17-19H,1-2,9-16H2,(H,29,33) LILXYDLYNDJABW-UHFFFAOYSA-N 50001992 1-(4-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-butyl)-imidazolidin-2-one::CHEMBL274648 D(2) dopamine receptor Rattus norvegicus 78 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001992&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006461 103916345 CHEMBL274648 ZINC13452494 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003467 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)C(F)(F)F InChI=1S/C25H26F4N4O/c26-19-2-4-20(5-3-19)33-16-22(21-15-18(25(27,28)29)1-6-23(21)33)17-7-10-31(11-8-17)13-14-32-12-9-30-24(32)34/h1-6,15-17H,7-14H2,(H,30,34) WYZQZAVJYFIRQK-UHFFFAOYSA-N 50001997 1-(2-{4-[1-(4-Fluoro-phenyl)-5-trifluoromethyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL12910 D(2) dopamine receptor Rattus norvegicus 1.9 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001997&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006458 103916350 CHEMBL12910 ZINC13452471 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003470 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3ccc(Cl)cc23)C1=O InChI=1S/C27H32ClFN4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)25-18-33(23-6-4-22(29)5-7-23)26-8-3-21(28)17-24(25)26/h3-8,17-20H,9-16H2,1-2H3 ZGDSCXWBGXHUHE-UHFFFAOYSA-N 50002007 1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL274861 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002007&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006465 103916360 CHEMBL274861 ZINC13452513 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003471 COc1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C25H29FN4O2/c1-32-21-6-7-24-22(16-21)23(17-30(24)20-4-2-19(26)3-5-20)18-8-11-28(12-9-18)14-15-29-13-10-27-25(29)31/h2-7,16-18H,8-15H2,1H3,(H,27,31) KTOKSMAKXHBMJM-UHFFFAOYSA-N 50002014 1-(2-{4-[1-(4-Fluoro-phenyl)-5-methoxy-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL13048 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002014&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006459 103916367 CHEMBL13048 ZINC13452485 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003474 Fc1ccc(cc1)-n1cc(C2CCN(CCCCCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C27H32ClFN4O/c28-21-4-9-26-24(18-21)25(19-33(26)23-7-5-22(29)6-8-23)20-10-15-31(16-11-20)13-2-1-3-14-32-17-12-30-27(32)34/h4-9,18-20H,1-3,10-17H2,(H,30,34) AFKBRSCMNVQDCS-UHFFFAOYSA-N 50002010 1-(5-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-pentyl)-imidazolidin-2-one::CHEMBL418160 D(2) dopamine receptor Rattus norvegicus 4.2 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002010&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006462 103916363 CHEMBL418160 ZINC13452499 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003476 CN1CCC(=CC1)c1cn(-c2ccc(F)cc2)c2ccc(F)cc12 InChI=1S/C20H18F2N2/c1-23-10-8-14(9-11-23)19-13-24(17-5-2-15(21)3-6-17)20-7-4-16(22)12-18(19)20/h2-8,12-13H,9-11H2,1H3 ZFOGIHQMXAYDAX-UHFFFAOYSA-N 50001996 5-Fluoro-1-(4-fluoro-phenyl)-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL268974 D(2) dopamine receptor Rattus norvegicus 0.740000 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006441 103916349 CHEMBL268974 ZINC13452421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003477 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(F)ccc12 InChI=1S/C24H26F2N4O/c25-18-1-4-20(5-2-18)30-16-22(21-15-19(26)3-6-23(21)30)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) UEWDNBBZGQGYEW-UHFFFAOYSA-N 50002001 1-(2-{4-[5-Fluoro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL269679 D(2) dopamine receptor Rattus norvegicus 4.7 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002001&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006455 103916354 CHEMBL269679 ZINC13452455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003480 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Br)ccc12 InChI=1S/C24H26BrFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) YJMZMRGHNASRLZ-UHFFFAOYSA-N 50002013 1-(2-{4-[5-Bromo-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL12235 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002013&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006456 103916366 CHEMBL12235 ZINC13452461 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003481 OCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C21H22ClFN2O/c22-16-1-6-21-19(13-16)20(15-7-9-24(10-8-15)11-12-26)14-25(21)18-4-2-17(23)3-5-18/h1-6,13-15,26H,7-12H2 ANOQQUDEPUAIRE-UHFFFAOYSA-N 50001995 2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethanol::CHEMBL430151 D(2) dopamine receptor Rattus norvegicus 4.5 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006448 103916348 CHEMBL430151 ZINC13452446 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003482 CN1CCC(=CC1)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C20H18ClFN2/c1-23-10-8-14(9-11-23)19-13-24(17-5-3-16(22)4-6-17)20-7-2-15(21)12-18(19)20/h2-8,12-13H,9-11H2,1H3 VMZWFUNEODYUEN-UHFFFAOYSA-N 50002015 5-Chloro-1-(4-fluoro-phenyl)-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL12507 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002015&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15648963 103916368 CHEMBL12507 ZINC13452416 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003483 Clc1ccc2[nH]cc(C3CCN(CCN4CCNC4=O)CC3)c2c1 InChI=1S/C18H23ClN4O/c19-14-1-2-17-15(11-14)16(12-21-17)13-3-6-22(7-4-13)9-10-23-8-5-20-18(23)24/h1-2,11-13,21H,3-10H2,(H,20,24) UFIWZMXMDVOAMC-UHFFFAOYSA-N 50002016 1-{2-[4-(5-Chloro-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-imidazolidin-2-one::CHEMBL13053 D(2) dopamine receptor Rattus norvegicus 810 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002016&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006472 103916369 CHEMBL13053 ZINC12356109 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003485 CN1CCN(CC1)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C19H19ClFN3/c1-22-8-10-23(11-9-22)19-13-24(16-5-3-15(21)4-6-16)18-7-2-14(20)12-17(18)19/h2-7,12-13H,8-11H2,1H3 LSIVEFHSNHEZSG-UHFFFAOYSA-N 50001990 5-Chloro-1-(4-fluoro-phenyl)-3-(4-methyl-piperazin-1-yl)-1H-indole::CHEMBL273516 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001990&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006415 103916343 CHEMBL273516 ZINC13452401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003488 Fc1ccc(cc1)-n1cc(N2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C23H25ClFN5O/c24-17-1-6-21-20(15-17)22(16-30(21)19-4-2-18(25)3-5-19)28-12-9-27(10-13-28)11-14-29-8-7-26-23(29)31/h1-6,15-16H,7-14H2,(H,26,31) YWEZQLWOBZAAFY-UHFFFAOYSA-N 50001998 1-(2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL275494 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001998&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006416 103916351 CHEMBL275494 ZINC13452405 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003489 Cc1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C25H29FN4O/c1-18-2-7-24-22(16-18)23(17-30(24)21-5-3-20(26)4-6-21)19-8-11-28(12-9-19)14-15-29-13-10-27-25(29)31/h2-7,16-17,19H,8-15H2,1H3,(H,27,31) ARZIOMWQBRPJMY-UHFFFAOYSA-N 50002008 1-(2-{4-[1-(4-Fluoro-phenyl)-5-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL267304 D(2) dopamine receptor Rattus norvegicus 3.7 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002008&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006457 103916361 CHEMBL267304 ZINC13452466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003537 CC1SC(C)(C)C(=O)N1CCCCN1CCN(CC1)c1csc2cc(F)ccc12 InChI=1S/C22H30FN3OS2/c1-16-26(21(27)22(2,3)29-16)9-5-4-8-24-10-12-25(13-11-24)19-15-28-20-14-17(23)6-7-18(19)20/h6-7,14-16H,4-5,8-13H2,1-3H3 IWOQWCKSTOAOMQ-UHFFFAOYSA-N 50002107 3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-2,5,5-trimethyl-thiazolidin-4-one::CHEMBL89934 D(2) dopamine receptor Rattus norvegicus 520 ChEMBL 10.1021/jm00092a024 10.7270/Q2TH8KMC 1353116 Hrib, NJ; Jurcak, JG; Bregna, DE; Dunn, RW; Geyer, HM; Hartman, HB; Roehr, JE; Rogers, KL; Rush, DK; Szczepanik, AM Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131396 103916416 CHEMBL89934 ZINC03793084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003539 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00092a024 10.7270/Q2TH8KMC 1353116 Hrib, NJ; Jurcak, JG; Bregna, DE; Dunn, RW; Geyer, HM; Hartman, HB; Roehr, JE; Rogers, KL; Rush, DK; Szczepanik, AM Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003545 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 790.0 ChEMBL 10.1021/jm00092a024 10.7270/Q2TH8KMC 1353116 Hrib, NJ; Jurcak, JG; Bregna, DE; Dunn, RW; Geyer, HM; Hartman, HB; Roehr, JE; Rogers, KL; Rush, DK; Szczepanik, AM Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002501 CCCN(CCC)[C@H]1CCn2cccc2C1 InChI=1S/C14H24N2/c1-3-8-15(9-4-2)14-7-11-16-10-5-6-13(16)12-14/h5-6,10,14H,3-4,7-9,11-12H2,1-2H3/t14-/m0/s1 BCXCDTKLXHURCX-AWEZNQCLSA-N 50366327 CHEMBL192037 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1016/S0960-894X(00)80003-7 10.7270/Q2MS3T7B Gmeiner, P; Sommer, J; Mierau, J; Hofner, G TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15720219 160845429 CHEMBL192037 ZINC05833146 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002502 NC1Cc2cnn3cccc(C1)c23 InChI=1S/C10H11N3/c11-9-4-7-2-1-3-13-10(7)8(5-9)6-12-13/h1-3,6,9H,4-5,11H2 PRZSHWXHGWAKRK-UHFFFAOYSA-N 50282000 4,5-Dihydro-3H-pyrazolo[4,5,1-ij]quinolin-4-ylamine::CHEMBL433233 D(2) dopamine receptor Rattus norvegicus 2800 ChEMBL 10.1016/S0960-894X(00)80003-7 10.7270/Q2MS3T7B Gmeiner, P; Sommer, J; Mierau, J; Hofner, G TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50282000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50282000&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283224 104123674 CHEMBL433233 ZINC29247944 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002503 CCCNC1Cc2cnn3cccc(C1)c23 InChI=1S/C13H17N3/c1-2-5-14-12-7-10-4-3-6-16-13(10)11(8-12)9-15-16/h3-4,6,9,12,14H,2,5,7-8H2,1H3 VYXFGMDFSNPGEX-UHFFFAOYSA-N 50281999 (4,5-Dihydro-3H-pyrazolo[4,5,1-ij]quinolin-4-yl)-propyl-amine::CHEMBL34022 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1016/S0960-894X(00)80003-7 10.7270/Q2MS3T7B Gmeiner, P; Sommer, J; Mierau, J; Hofner, G TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281999&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283225 104123673 CHEMBL34022 ZINC29247953 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50001444 Nc1nc2CC[C@@H](Cc2s1)N1CCN(CC1)c1ccccn1 InChI=1S/C16H21N5S/c17-16-19-13-5-4-12(11-14(13)22-16)20-7-9-21(10-8-20)15-3-1-2-6-18-15/h1-3,6,12H,4-5,7-11H2,(H2,17,19)/t12-/m0/s1 FPNSOJRXMGJRFL-LBPRGKRZSA-N 50279867 (S)-6-(4-Pyridin-2-yl-piperazin-1-yl)-4,5,6,7-tetrahydro-benzothiazol-2-ylamine::CHEMBL56584 D(2) dopamine receptor Rattus norvegicus 800 ChEMBL 10.1016/S0960-894X(00)80249-8 10.7270/Q2ZC83BV Jaen, JC; Caprathe, BW; Wise, LD; Smith, SJ; Pugsley, TA; Heffner, TG; Meltzer, LT TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15681504 104121571 CHEMBL56584 ZINC29554524 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50001449 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1016/S0960-894X(00)80249-8 10.7270/Q2ZC83BV Jaen, JC; Caprathe, BW; Wise, LD; Smith, SJ; Pugsley, TA; Heffner, TG; Meltzer, LT TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003649 Clc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H25ClN2/c24-21-9-10-23-22(16-21)20(17-25-23)8-4-5-13-26-14-11-19(12-15-26)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,25H,4-5,8,12-15H2 WWBXRAAWXACMHT-UHFFFAOYSA-N 50002160 5-Chloro-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL132446 D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002160&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10340978 103916466 CHEMBL132446 ZINC13728613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003650 COc1ccc2c(CCCCN3CCC(=CC3)c3ccccc3)c[nH]c2c1 InChI=1S/C24H28N2O/c1-27-22-10-11-23-21(18-25-24(23)17-22)9-5-6-14-26-15-12-20(13-16-26)19-7-3-2-4-8-19/h2-4,7-8,10-12,17-18,25H,5-6,9,13-16H2,1H3 PUZDYVQNYUCMKE-UHFFFAOYSA-N 50002175 6-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL130659 D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002175&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10475895 103916481 CHEMBL130659 ZINC13728616 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003651 Fc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H25FN2/c24-21-9-10-23-22(16-21)20(17-25-23)8-4-5-13-26-14-11-19(12-15-26)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,25H,4-5,8,12-15H2 CHPQXURJLAVZHE-UHFFFAOYSA-N 50002158 5-Fluoro-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL338710 D(2) dopamine receptor Rattus norvegicus 1.6 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10475149 103916464 CHEMBL338710 ZINC13728610 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003655 C(CCc1c[nH]c2ccccc12)CN1CCC=CC1 InChI=1S/C17H22N2/c1-5-11-19(12-6-1)13-7-4-8-15-14-18-17-10-3-2-9-16(15)17/h1-3,5,9-10,14,18H,4,6-8,11-13H2 RNGZXDOUGRHLBQ-UHFFFAOYSA-N 50002161 3-[4-(3,6-Dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL130605 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002161&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10446977 103916467 CHEMBL130605 ZINC13728598 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003656 C(Cc1c[nH]c2ccccc12)N1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c1-2-6-17(7-3-1)18-10-13-23(14-11-18)15-12-19-16-22-21-9-5-4-8-20(19)21/h1-10,16,22H,11-15H2 ANEFQMOYWNJZFI-UHFFFAOYSA-N 50002163 3-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-1H-indole::CHEMBL127609 D(2) dopamine receptor Rattus norvegicus 81 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002163&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086288 103916469 CHEMBL127609 ZINC13728571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003657 Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 HGEYJZMMUGWEOT-UHFFFAOYSA-N 50002173 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole D(2) dopamine receptor Rattus norvegicus 0.880000 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 219050 103916479 48558 CHEMBL431367 52 ZINC01548439 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003661 COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C24H28N2O/c1-27-22-10-11-24-23(17-22)21(18-25-24)9-5-6-14-26-15-12-20(13-16-26)19-7-3-2-4-8-19/h2-4,7-8,10-12,17-18,25H,5-6,9,13-16H2,1H3 OUSYTGMUXWLOBH-UHFFFAOYSA-N 50002177 5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::5-methoxy-3-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-1H-indole::CHEMBL130327 D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10408477 103916483 CHEMBL130327 ZINC13582350 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003663 Fc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H25FN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-12,17,25H,3-5,13-16H2 WOQPWODQIGGKJL-UHFFFAOYSA-N 50002171 3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL64344 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10452645 103916477 CHEMBL64344 ZINC13728583 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003665 C(CN1CCC(=CC1)c1ccccc1)Cc1c[nH]c2ccccc12 InChI=1S/C22H24N2/c1-2-7-18(8-3-1)19-12-15-24(16-13-19)14-6-9-20-17-23-22-11-5-4-10-21(20)22/h1-5,7-8,10-12,17,23H,6,9,13-16H2 XDNNWNKVOIAXTP-UHFFFAOYSA-N 50002170 3-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-1H-indole::CHEMBL131841 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10089397 103916476 CHEMBL131841 ZINC13728574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003667 Cn1cc(CCCCN2CCC(=CC2)c2ccccc2)c2ccccc12 InChI=1S/C24H28N2/c1-25-19-22(23-12-5-6-13-24(23)25)11-7-8-16-26-17-14-21(15-18-26)20-9-3-2-4-10-20/h2-6,9-10,12-14,19H,7-8,11,15-18H2,1H3 XJWCIRDJJRTWNX-UHFFFAOYSA-N 50002159 1-Methyl-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL131356 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002159&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10474937 103916465 CHEMBL131356 ZINC13728604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003668 Oc1ccc2c(CCCCN3CCC(=CC3)c3ccccc3)c[nH]c2c1 InChI=1S/C23H26N2O/c26-21-9-10-22-20(17-24-23(22)16-21)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 KELIDAHPKTUDBD-UHFFFAOYSA-N 50002169 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indol-6-ol::CHEMBL130502 D(2) dopamine receptor Rattus norvegicus 2.5 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10315634 103916475 CHEMBL130502 ZINC13728619 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003671 Clc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H25ClN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-12,17,25H,3-5,13-16H2 VDPNPEDMQPLESI-UHFFFAOYSA-N 50002166 3-{4-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL130501 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10386308 103916472 CHEMBL130501 ZINC13728589 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003672 Clc1ccccc1C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H25ClN2/c24-22-10-3-1-8-20(22)18-12-15-26(16-13-18)14-6-5-7-19-17-25-23-11-4-2-9-21(19)23/h1-4,8-12,17,25H,5-7,13-16H2 WWMBSJAUCLHJCQ-UHFFFAOYSA-N 50002165 3-{4-[4-(2-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL131711 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10250440 103916471 CHEMBL131711 ZINC13728592 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003673 C(CCc1c[nH]c2ccccc12)CN1CCC(=CC1)c1ccccc1 InChI=1S/C23H26N2/c1-2-8-19(9-3-1)20-13-16-25(17-14-20)15-7-6-10-21-18-24-23-12-5-4-11-22(21)23/h1-5,8-9,11-13,18,24H,6-7,10,14-17H2 AACJICLCLVMZKK-UHFFFAOYSA-N 50002172 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL44231 D(2) dopamine receptor Rattus norvegicus 105 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6917760 103916478 CHEMBL44231 ZINC02541533 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003674 Fc1ccccc1C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H25FN2/c24-22-10-3-1-8-20(22)18-12-15-26(16-13-18)14-6-5-7-19-17-25-23-11-4-2-9-21(19)23/h1-4,8-12,17,25H,5-7,13-16H2 FNJKJLLZOPKWHV-UHFFFAOYSA-N 50002174 3-{4-[4-(2-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL132270 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10247167 103916480 CHEMBL132270 ZINC13728586 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003676 Cc1[nH]c2ccccc2c1CCCCN1CCC(=CC1)c1ccccc1 InChI=1S/C24H28N2/c1-19-22(23-12-5-6-13-24(23)25-19)11-7-8-16-26-17-14-21(15-18-26)20-9-3-2-4-10-20/h2-6,9-10,12-14,25H,7-8,11,15-18H2,1H3 VPAZYSLQUPECFV-UHFFFAOYSA-N 50002162 2-Methyl-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL338849 D(2) dopamine receptor Rattus norvegicus 5.4 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002162&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10407449 103916468 CHEMBL338849 ZINC13728607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003677 C(CCc1c[nH]c2ccccc12)CN1CCC(CC1)c1ccccc1 InChI=1S/C23H28N2/c1-2-8-19(9-3-1)20-13-16-25(17-14-20)15-7-6-10-21-18-24-23-12-5-4-11-22(21)23/h1-5,8-9,11-12,18,20,24H,6-7,10,13-17H2 JHLJHQQFPBTTJE-UHFFFAOYSA-N 50002164 3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole::CHEMBL59335 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002164&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10451707 103916470 CHEMBL59335 ZINC13728601 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003679 C(CCN1CCC(=CC1)c1ccccc1)CCc1c[nH]c2ccccc12 InChI=1S/C24H28N2/c1-3-9-20(10-4-1)21-14-17-26(18-15-21)16-8-2-5-11-22-19-25-24-13-7-6-12-23(22)24/h1,3-4,6-7,9-10,12-14,19,25H,2,5,8,11,15-18H2 RDMGNUHCWDMCMI-UHFFFAOYSA-N 50002167 3-[5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-pentyl]-1H-indole::CHEMBL419957 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002167&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10091199 103916473 CHEMBL419957 ZINC13728577 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003680 C(CCCc1c[nH]c2ccccc12)CCN1CCC(=CC1)c1ccccc1 InChI=1S/C25H30N2/c1(4-12-23-20-26-25-14-8-7-13-24(23)25)2-9-17-27-18-15-22(16-19-27)21-10-5-3-6-11-21/h3,5-8,10-11,13-15,20,26H,1-2,4,9,12,16-19H2 IAKOYHDOZKAROP-UHFFFAOYSA-N 50002176 3-[6-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-hexyl]-1H-indole::CHEMBL130614 D(2) dopamine receptor Rattus norvegicus 4.3 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002176&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977979 103916482 CHEMBL130614 ZINC13728580 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003682 COc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C24H28N2O/c1-27-22-11-9-19(10-12-22)20-13-16-26(17-14-20)15-5-4-6-21-18-25-24-8-3-2-7-23(21)24/h2-3,7-13,18,25H,4-6,14-17H2,1H3 KKBZGGCJLOKSKV-UHFFFAOYSA-N 50002168 3-{4-[4-(4-Methoxy-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL339954 D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002168&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10092189 103916474 CHEMBL339954 ZINC13728595 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008741 Oc1ccc2CC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m1/s1 DWUAAOIZQFTYQP-MRXNPFEDSA-N 50061669 (R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL134807::CHEMBL64553 D(2) dopamine receptor Rattus norvegicus 0.160000 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378389 103957219 CHEMBL134807CHEMBL64553 ZINC13527706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008742 C(N1CCN(CC1)c1ccccc1)c1ccccc1 InChI=1S/C17H20N2/c1-3-7-16(8-4-1)15-18-11-13-19(14-12-18)17-9-5-2-6-10-17/h1-10H,11-15H2 VEJWDLHOLWGRLH-UHFFFAOYSA-N 50069919 1-Benzyl-4-phenyl-piperazine::CHEMBL101032 D(2) dopamine receptor Rattus norvegicus 124 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069919&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 511484 103963881 CHEMBL101032 ZINC12629325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008745 CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1Cl InChI=1S/C16H19ClN2O3S/c1-23(20,21)19-16-11-14(7-8-15(16)17)22-10-9-18-12-13-5-3-2-4-6-13/h2-8,11,18-19H,9-10,12H2,1H3 GJAYJBGLRYDTKW-UHFFFAOYSA-N 50069921 CHEMBL99913::N-[5-(2-Benzylamino-ethoxy)-2-chloro-phenyl]-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332565 103963883 CHEMBL99913 ZINC26752280 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008746 CS(=O)(=O)Nc1cc(OCCNCc2cccs2)ccc1F InChI=1S/C14H17FN2O3S2/c1-22(18,19)17-14-9-11(4-5-13(14)15)20-7-6-16-10-12-3-2-8-21-12/h2-5,8-9,16-17H,6-7,10H2,1H3 ORNYDPYZWVONOG-UHFFFAOYSA-N 50069913 CHEMBL101910::N-(2-Fluoro-5-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-phenyl)-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069913&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332613 103963875 CHEMBL101910 ZINC26820138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008748 Oc1ccccc1OCCNCc1ccccc1 InChI=1S/C15H17NO2/c17-14-8-4-5-9-15(14)18-11-10-16-12-13-6-2-1-3-7-13/h1-9,16-17H,10-12H2 VNAZBTWTBGIYND-UHFFFAOYSA-N 50069906 2-(2-Benzylamino-ethoxy)-phenol::CHEMBL101285 D(2) dopamine receptor Rattus norvegicus 9.6 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069906&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332581 103963868 CHEMBL101285 ZINC26750210 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008752 Oc1ccccc1N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-9-5-4-8-16(17)19-12-10-18(11-13-19)14-15-6-2-1-3-7-15/h1-9,20H,10-14H2 FPVKDWNGSLXDRY-UHFFFAOYSA-N 50069916 2-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL100952 D(2) dopamine receptor Rattus norvegicus 65 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069916&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8529065 103963878 CHEMBL100952 ZINC53165591 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008755 Oc1ccc2OC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C16H17NO3/c18-13-6-7-15-16(8-13)20-14(11-19-15)10-17-9-12-4-2-1-3-5-12/h1-8,14,17-18H,9-11H2/t14-/m0/s1 DYWYWIOQKKRAST-AWEZNQCLSA-N 50061642 (S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]dioxin-6-ol; oxalic acid::CHEMBL300571::CHEMBL423890 D(2) dopamine receptor Rattus norvegicus 0.350000 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10612157 103957192 CHEMBL300571CHEMBL423890 ZINC13775979 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120576 Oc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2 VBTFJGYCISLKEQ-UHFFFAOYSA-N 50069914 3-(2-Benzylamino-ethoxy)-phenol::CHEMBL64508 D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069914&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11776546 103963876 CHEMBL64508 ZINC12355952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120577 CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1F InChI=1S/C16H19FN2O3S/c1-23(20,21)19-16-11-14(7-8-15(16)17)22-10-9-18-12-13-5-3-2-4-6-13/h2-8,11,18-19H,9-10,12H2,1H3 HEHPXIHFYMLODY-UHFFFAOYSA-N 50069912 CHEMBL323118::N-[5-(2-Benzylamino-ethoxy)-2-fluoro-phenyl]-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069912&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332646 103963874 CHEMBL323118 ZINC26743453 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120604 CS(=O)(=O)Nc1cc(OCCNCc2cccs2)ccc1Cl InChI=1S/C14H17ClN2O3S2/c1-22(18,19)17-14-9-11(4-5-13(14)15)20-7-6-16-10-12-3-2-8-21-12/h2-5,8-9,16-17H,6-7,10H2,1H3 RGVJFPMOLSXLGJ-UHFFFAOYSA-N 50069908 CHEMBL102490::N-(2-Chloro-5-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-phenyl)-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 6 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069908&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332701 103963870 CHEMBL102490 ZINC26823792 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120646 Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-4-7-16(13-17)19-11-9-18(10-12-19)14-15-5-2-1-3-6-15/h1-8,13,20H,9-12,14H2 BISVFNHMXVNVMG-UHFFFAOYSA-N 50069907 1-benzyl-4-(3-hydroxyphenyl)piperazine::3-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL88365 D(2) dopamine receptor Rattus norvegicus 95 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015867 103963869 CHEMBL88365 ZINC26638652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50574999 C(COc1ccccc1)NCc1ccccc1 InChI=1S/C15H17NO/c1-3-7-14(8-4-1)13-16-11-12-17-15-9-5-2-6-10-15/h1-10,16H,11-13H2 XTNXLNGNJZRBRW-UHFFFAOYSA-N 50069917 Benzyl-(2-phenoxy-ethyl)-amine::CHEMBL103951 D(2) dopamine receptor Rattus norvegicus 241 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20256387 103963879 CHEMBL103951 ZINC26816095 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50575000 CS(=O)(=O)Nc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C16H20N2O3S/c1-22(19,20)18-15-8-5-9-16(12-15)21-11-10-17-13-14-6-3-2-4-7-14/h2-9,12,17-18H,10-11,13H2,1H3 ZMVMIDCCNZYMFG-UHFFFAOYSA-N 50069918 CHEMBL99849::N-[3-(2-Benzylamino-ethoxy)-phenyl]-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332686 103963880 CHEMBL99849 ZINC26752574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008743 Oc1ccccc1OCCNCc1ccccc1 InChI=1S/C15H17NO2/c17-14-8-4-5-9-15(14)18-11-10-16-12-13-6-2-1-3-7-13/h1-9,16-17H,10-12H2 VNAZBTWTBGIYND-UHFFFAOYSA-N 50069906 2-(2-Benzylamino-ethoxy)-phenol::CHEMBL101285 D(2) dopamine receptor Rattus norvegicus 191 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069906&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332581 103963868 CHEMBL101285 ZINC26750210 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008744 CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1Cl InChI=1S/C16H19ClN2O3S/c1-23(20,21)19-16-11-14(7-8-15(16)17)22-10-9-18-12-13-5-3-2-4-6-13/h2-8,11,18-19H,9-10,12H2,1H3 GJAYJBGLRYDTKW-UHFFFAOYSA-N 50069921 CHEMBL99913::N-[5-(2-Benzylamino-ethoxy)-2-chloro-phenyl]-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 3.00 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332565 103963883 CHEMBL99913 ZINC26752280 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008747 C(N1CCN(CC1)c1ccccc1)c1ccccc1 InChI=1S/C17H20N2/c1-3-7-16(8-4-1)15-18-11-13-19(14-12-18)17-9-5-2-6-10-17/h1-10H,11-15H2 VEJWDLHOLWGRLH-UHFFFAOYSA-N 50069919 1-Benzyl-4-phenyl-piperazine::CHEMBL101032 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069919&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 511484 103963881 CHEMBL101032 ZINC12629325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008750 CS(=O)(=O)Nc1cc(OCCNCc2ccccc2)ccc1F InChI=1S/C16H19FN2O3S/c1-23(20,21)19-16-11-14(7-8-15(16)17)22-10-9-18-12-13-5-3-2-4-6-13/h2-8,11,18-19H,9-10,12H2,1H3 HEHPXIHFYMLODY-UHFFFAOYSA-N 50069912 CHEMBL323118::N-[5-(2-Benzylamino-ethoxy)-2-fluoro-phenyl]-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 7.9 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069912&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332646 103963874 CHEMBL323118 ZINC26743453 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008751 Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-4-7-16(13-17)19-11-9-18(10-12-19)14-15-5-2-1-3-6-15/h1-8,13,20H,9-12,14H2 BISVFNHMXVNVMG-UHFFFAOYSA-N 50069907 1-benzyl-4-(3-hydroxyphenyl)piperazine::3-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL88365 D(2) dopamine receptor Rattus norvegicus 95.1 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015867 103963869 CHEMBL88365 ZINC26638652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008754 Oc1ccc2CC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m1/s1 DWUAAOIZQFTYQP-MRXNPFEDSA-N 50061669 (R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL134807::CHEMBL64553 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378389 103957219 CHEMBL134807CHEMBL64553 ZINC13527706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50009009 CCN1CCCC[C@@H](C1)NC(=O)c1cc(Cl)c(NC)cc1OC InChI=1S/C17H26ClN3O2/c1-4-21-8-6-5-7-12(11-21)20-17(22)13-9-14(18)15(19-2)10-16(13)23-3/h9-10,12,19H,4-8,11H2,1-3H3,(H,20,22)/t12-/m0/s1 QCORICSISJGQIZ-LBPRGKRZSA-N 50450877 CHEMBL2093035 D(2) dopamine receptor Rattus norvegicus 367 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450877&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70687144 225145215 CHEMBL2093035 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50009011 CCN1CCN(C)C[C@@H](C1)NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C16H25ClN4O2/c1-4-21-6-5-20(2)9-11(10-21)19-16(22)12-7-13(17)14(18)8-15(12)23-3/h7-8,11H,4-6,9-10,18H2,1-3H3,(H,19,22)/t11-/m0/s1 ATMCNNNBGDVDQH-NSHDSACASA-N 50450876 CHEMBL2093034 D(2) dopamine receptor Rattus norvegicus 517 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450876&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10882378 225145214 CHEMBL2093034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50009031 CCN1CCCC[C@@H](C1)NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C16H24ClN3O2/c1-3-20-7-5-4-6-11(10-20)19-16(21)12-8-13(17)14(18)9-15(12)22-2/h8-9,11H,3-7,10,18H2,1-2H3,(H,19,21)/t11-/m0/s1 UREJLDJPNXRLEF-NSHDSACASA-N 50450878 CHEMBL2093036 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50450878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50450878&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70693406 225145216 CHEMBL2093036 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006885 Fc1ccc(CN2CN(c3ccccc3)C3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)C2=O)cc1 InChI=1S/C30H31F2N3O2/c31-25-12-8-23(9-13-25)21-34-22-35(27-5-2-1-3-6-27)30(29(34)37)16-19-33(20-17-30)18-4-7-28(36)24-10-14-26(32)15-11-24/h1-3,5-6,8-15H,4,7,16-22H2 OANMKJFCXAFBPM-UHFFFAOYSA-N 50004800 3-(4-Fluoro-benzyl)-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL538404 D(2) dopamine receptor Rattus norvegicus 0.069000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14816751 103918347 CHEMBL538404 ZINC13448530 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006888 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CN(CCc1ccccc1)C2=O)c1ccccc1 InChI=1S/C31H34FN3O2/c32-27-15-13-26(14-16-27)29(36)12-7-20-33-22-18-31(19-23-33)30(37)34(21-17-25-8-3-1-4-9-25)24-35(31)28-10-5-2-6-11-28/h1-6,8-11,13-16H,7,12,17-24H2 BBIKLYNFXVJLRQ-UHFFFAOYSA-N 50004803 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-phenethyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL337149 D(2) dopamine receptor Rattus norvegicus 0.035000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121351 103918350 CHEMBL337149 ZINC13448523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006889 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CN(Cc1ccccc1I)C2=O)c1ccccc1 InChI=1S/C30H31FIN3O2/c31-25-14-12-23(13-15-25)28(36)11-6-18-33-19-16-30(17-20-33)29(37)34(21-24-7-4-5-10-27(24)32)22-35(30)26-8-2-1-3-9-26/h1-5,7-10,12-15H,6,11,16-22H2 OJTMBEATTITROZ-UHFFFAOYSA-N 50004804 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(2-iodo-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL135500 D(2) dopamine receptor Rattus norvegicus 0.063000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004804&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121339 103918351 CHEMBL135500 ZINC27429368 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006890 CCCCN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C27H34FN3O2/c1-2-3-18-30-21-31(24-8-5-4-6-9-24)27(26(30)33)15-19-29(20-16-27)17-7-10-25(32)22-11-13-23(28)14-12-22/h4-6,8-9,11-14H,2-3,7,10,15-21H2,1H3 MUDRMLJUTREPSJ-UHFFFAOYSA-N 50004805 3-Butyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL136852 D(2) dopamine receptor Rattus norvegicus 0.036000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121346 103918352 CHEMBL136852 ZINC13448508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006891 Cc1ccc(CN2CN(c3ccccc3)C3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)C2=O)cc1 InChI=1S/C31H34FN3O2/c1-24-9-11-25(12-10-24)22-34-23-35(28-6-3-2-4-7-28)31(30(34)37)17-20-33(21-18-31)19-5-8-29(36)26-13-15-27(32)16-14-26/h2-4,6-7,9-16H,5,8,17-23H2,1H3 NUEVBZLYKCHOPY-UHFFFAOYSA-N 50004806 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(4-methyl-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL134545 D(2) dopamine receptor Rattus norvegicus 0.067000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121343 103918353 CHEMBL134545 ZINC13448542 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006893 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CN(Cc1ccccc1)C2=O)c1ccccc1 InChI=1S/C30H32FN3O2/c31-26-15-13-25(14-16-26)28(35)12-7-19-32-20-17-30(18-21-32)29(36)33(22-24-8-3-1-4-9-24)23-34(30)27-10-5-2-6-11-27/h1-6,8-11,13-16H,7,12,17-23H2 JASOLEMXZHFMTL-UHFFFAOYSA-N 50004808 3-Benzyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL134400 D(2) dopamine receptor Rattus norvegicus 0.023000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121350 103918355 CHEMBL134400 ZINC13448520 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006900 CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C24H28FN3O2/c1-26-18-28(21-6-3-2-4-7-21)24(23(26)30)13-16-27(17-14-24)15-5-8-22(29)19-9-11-20(25)12-10-19/h2-4,6-7,9-12H,5,8,13-18H2,1H3 QHJLPOSPWKZACG-UHFFFAOYSA-N 50004813 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one (N-methylspiperone,NMSP)::CHEMBL267932 D(2) dopamine receptor Rattus norvegicus 0.118000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 119146 103918360 CHEMBL267932 196 ZINC02572278 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006901 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CN(Cc1ccc(I)cc1)C2=O)c1ccccc1 InChI=1S/C30H31FIN3O2/c31-25-12-10-24(11-13-25)28(36)7-4-18-33-19-16-30(17-20-33)29(37)34(21-23-8-14-26(32)15-9-23)22-35(30)27-5-2-1-3-6-27/h1-3,5-6,8-15H,4,7,16-22H2 BKFRBKWZTZFMJW-UHFFFAOYSA-N 50004811 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(4-iodo-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL335714 D(2) dopamine receptor Rattus norvegicus 0.213000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121340 103918358 CHEMBL335714 ZINC27424817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006902 CCCCCN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C28H36FN3O2/c1-2-3-7-19-31-22-32(25-9-5-4-6-10-25)28(27(31)34)16-20-30(21-17-28)18-8-11-26(33)23-12-14-24(29)15-13-23/h4-6,9-10,12-15H,2-3,7-8,11,16-22H2,1H3 DGNKTCJDFITHNL-UHFFFAOYSA-N 50004802 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-pentyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL135316 D(2) dopamine receptor Rattus norvegicus 0.062000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121348 103918349 CHEMBL135316 ZINC13448514 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006904 COc1ccc(CN2CN(c3ccccc3)C3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)C2=O)cc1 InChI=1S/C31H34FN3O3/c1-38-28-15-9-24(10-16-28)22-34-23-35(27-6-3-2-4-7-27)31(30(34)37)17-20-33(21-18-31)19-5-8-29(36)25-11-13-26(32)14-12-25/h2-4,6-7,9-16H,5,8,17-23H2,1H3 ARMCHIDXFRTTKY-UHFFFAOYSA-N 50004812 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(4-methoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL335606 D(2) dopamine receptor Rattus norvegicus 0.087000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004812&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121345 103918359 CHEMBL335606 ZINC13448549 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006908 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CN(Cc1cccc(F)c1)C2=O)c1ccccc1 InChI=1S/C30H31F2N3O2/c31-25-13-11-24(12-14-25)28(36)10-5-17-33-18-15-30(16-19-33)29(37)34(21-23-6-4-7-26(32)20-23)22-35(30)27-8-2-1-3-9-27/h1-4,6-9,11-14,20H,5,10,15-19,21-22H2 DXZKTRNEOISOCA-UHFFFAOYSA-N 50004801 3-(3-Fluoro-benzyl)-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL137648 D(2) dopamine receptor Rattus norvegicus 0.023000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3248000 103918348 CHEMBL137648 ZINC03995320 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006909 [O-][N+](=O)c1ccc(CN2CN(c3ccccc3)C3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)C2=O)cc1 InChI=1S/C30H31FN4O4/c31-25-12-10-24(11-13-25)28(36)7-4-18-32-19-16-30(17-20-32)29(37)33(22-34(30)26-5-2-1-3-6-26)21-23-8-14-27(15-9-23)35(38)39/h1-3,5-6,8-15H,4,7,16-22H2 LUQXMQICZKCESV-UHFFFAOYSA-N 50004809 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(4-nitro-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL337181 D(2) dopamine receptor Rattus norvegicus 0.119000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121338 103918356 CHEMBL337181 ZINC13448536 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006913 CC(C)CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C27H34FN3O2/c1-21(2)19-30-20-31(24-7-4-3-5-8-24)27(26(30)33)14-17-29(18-15-27)16-6-9-25(32)22-10-12-23(28)13-11-22/h3-5,7-8,10-13,21H,6,9,14-20H2,1-2H3 ZQBJFINZRZWLFI-UHFFFAOYSA-N 50004807 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-isobutyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL334349 D(2) dopamine receptor Rattus norvegicus 0.039000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121347 103918354 CHEMBL334349 ZINC13448511 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006914 CCCN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C26H32FN3O2/c1-2-16-29-20-30(23-7-4-3-5-8-23)26(25(29)32)14-18-28(19-15-26)17-6-9-24(31)21-10-12-22(27)13-11-21/h3-5,7-8,10-13H,2,6,9,14-20H2,1H3 JDQUIRXNINRFHQ-UHFFFAOYSA-N 50004819 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1-phenyl-3-propyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL135917 D(2) dopamine receptor Rattus norvegicus 0.029000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 380265 103918366 CHEMBL135917 ZINC01640741 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006915 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CN(Cc1ccccc1F)C2=O)c1ccccc1 InChI=1S/C30H31F2N3O2/c31-25-14-12-23(13-15-25)28(36)11-6-18-33-19-16-30(17-20-33)29(37)34(21-24-7-4-5-10-27(24)32)22-35(30)26-8-2-1-3-9-26/h1-5,7-10,12-15H,6,11,16-22H2 HTULAWDUXVEOJC-UHFFFAOYSA-N 50004816 3-(2-Fluoro-benzyl)-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL137309 D(2) dopamine receptor Rattus norvegicus 0.043000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121352 103918363 CHEMBL137309 ZINC13448527 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006917 COc1ccccc1CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C31H34FN3O3/c1-38-29-12-6-5-8-25(29)22-34-23-35(27-9-3-2-4-10-27)31(30(34)37)17-20-33(21-18-31)19-7-11-28(36)24-13-15-26(32)16-14-24/h2-6,8-10,12-16H,7,11,17-23H2,1H3 ROIJHJVHNPMWIT-UHFFFAOYSA-N 50004810 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(2-methoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL135722 D(2) dopamine receptor Rattus norvegicus 0.047000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121344 103918357 CHEMBL135722 ZINC13448546 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006918 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.058000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006919 Cc1ccccc1CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C31H34FN3O2/c1-24-8-5-6-9-26(24)22-34-23-35(28-10-3-2-4-11-28)31(30(34)37)17-20-33(21-18-31)19-7-12-29(36)25-13-15-27(32)16-14-25/h2-6,8-11,13-16H,7,12,17-23H2,1H3 MRXPMPSDRAGQAV-UHFFFAOYSA-N 50004817 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(2-methyl-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL135832 D(2) dopamine receptor Rattus norvegicus 0.033000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121342 103918364 CHEMBL135832 ZINC13448539 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006921 CC(C)CCN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C28H36FN3O2/c1-22(2)14-18-31-21-32(25-7-4-3-5-8-25)28(27(31)34)15-19-30(20-16-28)17-6-9-26(33)23-10-12-24(29)13-11-23/h3-5,7-8,10-13,22H,6,9,14-21H2,1-2H3 ZMEQPYVPTDYEEM-UHFFFAOYSA-N 50004815 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(3-methyl-butyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL344399 D(2) dopamine receptor Rattus norvegicus 0.063000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121349 103918362 CHEMBL344399 ZINC13448517 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006925 [O-][N+](=O)c1ccccc1CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C30H31FN4O4/c31-25-14-12-23(13-15-25)28(36)11-6-18-32-19-16-30(17-20-32)29(37)33(22-34(30)26-8-2-1-3-9-26)21-24-7-4-5-10-27(24)35(38)39/h1-5,7-10,12-15H,6,11,16-22H2 DOYHXPOZCLMQII-UHFFFAOYSA-N 50004814 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-(2-nitro-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL135860 D(2) dopamine receptor Rattus norvegicus 0.120000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15121341 103918361 CHEMBL135860 ZINC13448533 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50006926 CCN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C25H30FN3O2/c1-2-28-19-29(22-7-4-3-5-8-22)25(24(28)31)14-17-27(18-15-25)16-6-9-23(30)20-10-12-21(26)13-11-20/h3-5,7-8,10-13H,2,6,9,14-19H2,1H3 PQBVNXQHADVWCG-UHFFFAOYSA-N 50004818 3-Ethyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL136942 D(2) dopamine receptor Rattus norvegicus 0.057000 ChEMBL 10.1021/jm00081a002 10.7270/Q2B85725 1531364 Mach, RH; Jackson, JR; Luedtke, RR; Ivins, KJ; Molinoff, PB; Ehrenkaufer, RL University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13497176 103918365 CHEMBL136942 ZINC13448505 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007047 Oc1cc2C(CN(CC=C)CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2 HJWHHQIVUHOBQN-UHFFFAOYSA-N 50004917 3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide(Cl-APB)::CHEMBL35354::CHEMBL544115::RS(+/-)-6-Cl-APB3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SKF 82958 D(2) dopamine receptor Rattus norvegicus 336 ChEMBL 10.1021/jm00086a016 10.7270/Q26H4GCW 1533424 Neumeyer, JL; Kula, NS; Baldessarini, RJ; Baindur, N Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1225 103918464 CHEMBL35354CHEMBL544115 ZINC03870318 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007048 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00086a016 10.7270/Q26H4GCW 1533424 Neumeyer, JL; Kula, NS; Baldessarini, RJ; Baindur, N Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007052 Oc1cc2CCNC[C@@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m0/s1 JUDKOGFHZYMDMF-AWEZNQCLSA-N 50004920 CHEMBL284746::S(-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus 720000 ChEMBL 10.1021/jm00086a016 10.7270/Q26H4GCW 1533424 Neumeyer, JL; Kula, NS; Baldessarini, RJ; Baindur, N Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004920&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603799 103918467 CHEMBL284746 ZINC01572556 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007055 Oc1cc2CCNCC(c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2 JUDKOGFHZYMDMF-UHFFFAOYSA-N 50004923 (+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514 D(2) dopamine receptor Rattus norvegicus 720000 ChEMBL 10.1021/jm00086a016 10.7270/Q26H4GCW 1533424 Neumeyer, JL; Kula, NS; Baldessarini, RJ; Baindur, N Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1242 103918470 CHEMBL505308CHEMBL286080CHEMBL542700 935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007056 Oc1cc2CCN(CC=C)CC(c3ccccc3)c2cc1O InChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2 QBUVZVXIRYFENV-UHFFFAOYSA-N 50004918 (+/-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride::CHEMBL288090::CHEMBL552611::SKF 77434 D(2) dopamine receptor Rattus norvegicus 2425 ChEMBL 10.1021/jm00086a016 10.7270/Q26H4GCW 1533424 Neumeyer, JL; Kula, NS; Baldessarini, RJ; Baindur, N Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1241 103918465 63988 CHEMBL552611CHEMBL288090 ZINC03870332 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007059 Oc1cc2CCN(CC=C)C[C@@H](c3ccccc3)c2cc1O InChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2/t17-/m0/s1 QBUVZVXIRYFENV-KRWDZBQOSA-N 50004924 CHEMBL286120::S-(-)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus 5000 ChEMBL 10.1021/jm00086a016 10.7270/Q26H4GCW 1533424 Neumeyer, JL; Kula, NS; Baldessarini, RJ; Baindur, N Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603997 103918471 63988 CHEMBL286120 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007060 Oc1cc2[C@H](CN(CC=C)CCc2c(Br)c1O)c1ccccc1 InChI=1S/C19H20BrNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m1/s1 KKZGFVAZUKHFAC-MRXNPFEDSA-N 50004921 (R)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)6-Br-APB)::CHEMBL34095::R-(+)6-Br-APD3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus 511.0 ChEMBL 10.1021/jm00086a016 10.7270/Q26H4GCW 1533424 Neumeyer, JL; Kula, NS; Baldessarini, RJ; Baindur, N Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10452020 103918468 CHEMBL34095 ZINC02530683 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007062 Oc1cc2C(CN(CC=C)CCc2c(Br)c1O)c1ccccc1 InChI=1S/C19H20BrNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2 KKZGFVAZUKHFAC-UHFFFAOYSA-N 50004922 3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide(Br-APB)::CHEMBL32145::CHEMBL544114::RS-(+/-)-6-Br-APD3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus 701 ChEMBL 10.1021/jm00086a016 10.7270/Q26H4GCW 1533424 Neumeyer, JL; Kula, NS; Baldessarini, RJ; Baindur, N Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004922&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5016 103918469 CHEMBL544114CHEMBL32145 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007064 Oc1cc2CCN(CC=C)C[C@H](c3ccccc3)c2cc1O InChI=1S/C19H21NO2/c1-2-9-20-10-8-15-11-18(21)19(22)12-16(15)17(13-20)14-6-4-3-5-7-14/h2-7,11-12,17,21-22H,1,8-10,13H2/t17-/m1/s1 QBUVZVXIRYFENV-QGZVFWFLSA-N 50004925 CHEMBL284473::R-(+)-APD3-Allyl-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus 1415 ChEMBL 10.1021/jm00086a016 10.7270/Q26H4GCW 1533424 Neumeyer, JL; Kula, NS; Baldessarini, RJ; Baindur, N Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004925&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720693 103918472 63988 CHEMBL284473 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007066 Oc1cc2[C@@H](CN(CC=C)CCc2c(Br)c1O)c1ccccc1 InChI=1S/C19H20BrNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m0/s1 KKZGFVAZUKHFAC-INIZCTEOSA-N 50004919 (R)(+)-BrAPB::CHEMBL286424::S-(-)-6-Br-APD3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus >5000 ChEMBL 10.1021/jm00086a016 10.7270/Q26H4GCW 1533424 Neumeyer, JL; Kula, NS; Baldessarini, RJ; Baindur, N Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004919&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603729 103918466 CHEMBL286424 ZINC02530682 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008158 O=c1[nH]c2cccc(N3CCN(Cc4ccccc4)CC3)c2[nH]1 InChI=1S/C18H20N4O/c23-18-19-15-7-4-8-16(17(15)20-18)22-11-9-21(10-12-22)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H2,19,20,23) MKJHGVZTPBBKML-UHFFFAOYSA-N 50071854 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL315864 D(2) dopamine receptor Rattus norvegicus 45.8 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18414156 103965564 CHEMBL315864 ZINC26648578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008159 Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-4-7-16(13-17)19-11-9-18(10-12-19)14-15-5-2-1-3-6-15/h1-8,13,20H,9-12,14H2 BISVFNHMXVNVMG-UHFFFAOYSA-N 50069907 1-benzyl-4-(3-hydroxyphenyl)piperazine::3-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL88365 D(2) dopamine receptor Rattus norvegicus 95 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015867 103963869 CHEMBL88365 ZINC26638652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008160 C(N1CCN(CC1)c1cccc2[nH]cnc12)c1ccccc1 InChI=1S/C18H20N4/c1-2-5-15(6-3-1)13-21-9-11-22(12-10-21)17-8-4-7-16-18(17)20-14-19-16/h1-8,14H,9-13H2,(H,19,20) ZNBOBGDGUIWKPE-UHFFFAOYSA-N 50071852 4-(4-Benzyl-piperazin-1-yl)-1H-benzoimidazole::CHEMBL88837 D(2) dopamine receptor Rattus norvegicus 107 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323762 103965562 CHEMBL88837 ZINC26579141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008161 Clc1ccc2[nH]ccc2c1N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H20ClN3/c20-17-6-7-18-16(8-9-21-18)19(17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-9,21H,10-14H2 IRFLVVGRMBDQSJ-UHFFFAOYSA-N 50071858 4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole::CHEMBL311539 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323978 103965568 CHEMBL311539 ZINC26580242 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008163 Brc1ccc(N2CCN(Cc3ccccc3)CC2)c2cc[nH]c12 InChI=1S/C19H20BrN3/c20-17-6-7-18(16-8-9-21-19(16)17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-9,21H,10-14H2 RBUDKKJLRVBPDA-UHFFFAOYSA-N 50071853 4-(4-Benzyl-piperazin-1-yl)-7-bromo-1H-indole::CHEMBL90476 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323962 103965563 CHEMBL90476 ZINC26650889 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008164 C(N1CCN(CC1)c1cccc2[nH]ccc12)c1ccccc1 InChI=1S/C19H21N3/c1-2-5-16(6-3-1)15-21-11-13-22(14-12-21)19-8-4-7-18-17(19)9-10-20-18/h1-10,20H,11-15H2 JLZIBIQTDGMAFZ-UHFFFAOYSA-N 50071857 4-(4-Benzyl-piperazin-1-yl)-1H-indole::CHEMBL328051 D(2) dopamine receptor Rattus norvegicus 3.2 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2728532 103965567 CHEMBL328051 ZINC53006914 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008165 FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H19F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H,23,24) PSWUORNVMIRUSW-UHFFFAOYSA-N 50071855 4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-benzoimidazole::CHEMBL88289 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323763 103965565 CHEMBL88289 ZINC26579142 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010574 CC[C@@H]1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C12H17NO3/c1-2-7-5-9-8(11(6-13)16-7)3-4-10(14)12(9)15/h3-4,7,11,14-15H,2,5-6,13H2,1H3/t7-,11+/m1/s1 YNUUJSAVGPCWBG-HQJQHLMTSA-N 50453079 CHEMBL2115213 D(2) dopamine receptor Rattus norvegicus 3530 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453079&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15696481 225145841 CHEMBL2115213 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010580 CC[C@H]1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C12H17NO3/c1-2-7-5-9-8(11(6-13)16-7)3-4-10(14)12(9)15/h3-4,7,11,14-15H,2,5-6,13H2,1H3/t7-,11-/m0/s1 YNUUJSAVGPCWBG-CPCISQLKSA-N 50453080 CHEMBL2114209 D(2) dopamine receptor Rattus norvegicus 5130 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453080&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15696482 225145842 CHEMBL2114209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010582 COc1ccc(CC2Cc3c(O)c(O)ccc3[C@H](CN)O2)cc1 InChI=1S/C18H21NO4/c1-22-12-4-2-11(3-5-12)8-13-9-15-14(17(10-19)23-13)6-7-16(20)18(15)21/h2-7,13,17,20-21H,8-10,19H2,1H3/t13?,17-/m0/s1 XSPPZAPYKHJYHP-RUINGEJQSA-N 50007143 1-Aminomethyl-3-(4-methoxy-benzyl)-isochroman-5,6-diol::CHEMBL87897 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007143&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320218 103920426 CHEMBL87897 ZINC26576269 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010587 NC[C@@H]1OCCc2c(O)c(O)ccc12 InChI=1S/C10H13NO3/c11-5-9-6-1-2-8(12)10(13)7(6)3-4-14-9/h1-2,9,12-13H,3-5,11H2/t9-/m0/s1 JBSRTZUQAXYSQB-VIFPVBQESA-N 50007135 1-Aminomethyl-isochroman-5,6-diol::CHEMBL87958 D(2) dopamine receptor Rattus norvegicus 2850 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007135&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13864380 103920418 CHEMBL87958 ZINC11422303 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010592 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14?,15-/m0/s1 SUHGRZPINGKYNV-LOACHALJSA-N 50007134 1-Aminomethyl-3-phenyl-isochroman-5,6-diol::CHEMBL315468 D(2) dopamine receptor Rattus norvegicus 776 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007134&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14809027 103920417 CHEMBL315468 ZINC06885604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010594 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)c1cccc(O)c1 InChI=1S/C16H17NO4/c17-8-15-11-4-5-13(19)16(20)12(11)7-14(21-15)9-2-1-3-10(18)6-9/h1-6,14-15,18-20H,7-8,17H2/t14?,15-/m0/s1 SVFKIIFLKICBPG-LOACHALJSA-N 50007137 1-Aminomethyl-3-(3-hydroxy-phenyl)-isochroman-5,6-diol::CHEMBL87734 D(2) dopamine receptor Rattus norvegicus 590 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007137&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320357 103920420 CHEMBL87734 ZINC26575470 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010599 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)c1ccc(I)cc1 InChI=1S/C16H16INO3/c17-10-3-1-9(2-4-10)14-7-12-11(15(8-18)21-14)5-6-13(19)16(12)20/h1-6,14-15,19-20H,7-8,18H2/t14?,15-/m0/s1 IFTXVACPDRUAPN-LOACHALJSA-N 50007152 1-Aminomethyl-3-(4-iodo-phenyl)-isochroman-5,6-diol::CHEMBL313304 D(2) dopamine receptor Rattus norvegicus 1055 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007152&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320061 103920435 CHEMBL313304 ZINC26575639 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010607 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)C(c1ccccc1)c1ccccc1 InChI=1S/C23H23NO3/c24-14-21-17-11-12-19(25)23(26)18(17)13-20(27-21)22(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-12,20-22,25-26H,13-14,24H2/t20?,21-/m0/s1 ILWGLMLPVXFDGW-LBAQZLPGSA-N 50007141 1-Aminomethyl-3-benzhydryl-isochroman-5,6-diol::CHEMBL87172 D(2) dopamine receptor Rattus norvegicus 2610 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007141&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320256 103920424 CHEMBL87172 ZINC26576775 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010608 NC[C@@H]1OC(CC#C)Cc2c(O)c(O)ccc12 InChI=1S/C13H15NO3/c1-2-3-8-6-10-9(12(7-14)17-8)4-5-11(15)13(10)16/h1,4-5,8,12,15-16H,3,6-7,14H2/t8?,12-/m0/s1 LWUHQVZWIKZZFZ-MYIOLCAUSA-N 50007151 1-Aminomethyl-3-prop-2-ynyl-isochroman-5,6-diol::CHEMBL315849 D(2) dopamine receptor Rattus norvegicus 1070 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007151&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320123 103920434 CHEMBL315849 ZINC26575532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010615 CN(CC=C)C[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C20H29NO3/c1-3-11-21(2)13-19-15-9-10-17(22)20(23)16(15)12-18(24-19)14-7-5-4-6-8-14/h3,9-10,14,18-19,22-23H,1,4-8,11-13H2,2H3/t18?,19-/m0/s1 JJNYVWDKXCESON-GGYWPGCISA-N 50007124 1-[(Allyl-methyl-amino)-methyl]-3-cyclohexyl-isochroman-5,6-diol::CHEMBL84557 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007124&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319915 103920407 CHEMBL84557 ZINC26569466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010616 NC[C@H]1O[C@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m1/s1 SUHGRZPINGKYNV-HUUCEWRRSA-N 50007136 1-Aminomethyl-3-phenyl-isochroman-5,6-diol::CHEMBL83080 D(2) dopamine receptor Rattus norvegicus 4610.0 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007136&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14809026 103920419 CHEMBL83080 ZINC04637270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010626 Oc1ccc2[C@H](CNC3CC3)OC(Cc2c1O)C1CCCCC1 InChI=1S/C19H27NO3/c21-16-9-8-14-15(19(16)22)10-17(12-4-2-1-3-5-12)23-18(14)11-20-13-6-7-13/h8-9,12-13,17-18,20-22H,1-7,10-11H2/t17?,18-/m0/s1 JMLFTEUVKWTNSN-ZVAWYAOSSA-N 50007138 3-Cyclohexyl-1-cyclopropylaminomethyl-isochroman-5,6-diol::CHEMBL86669 D(2) dopamine receptor Rattus norvegicus 636 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007138&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320328 103920421 CHEMBL86669 ZINC26576882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010627 COc1cccc(c1)C1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C17H19NO4/c1-21-11-4-2-3-10(7-11)15-8-13-12(16(9-18)22-15)5-6-14(19)17(13)20/h2-7,15-16,19-20H,8-9,18H2,1H3/t15?,16-/m0/s1 GKRQKKOXKDSLTJ-LYKKTTPLSA-N 50007139 1-Aminomethyl-3-(3-methoxy-phenyl)-isochroman-5,6-diol::CHEMBL315005 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007139&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319976 103920422 CHEMBL315005 ZINC26571642 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010632 Oc1ccc2[C@H](CNCc3ccccc3)OC(Cc2c1O)C1CCCCC1 InChI=1S/C23H29NO3/c25-20-12-11-18-19(23(20)26)13-21(17-9-5-2-6-10-17)27-22(18)15-24-14-16-7-3-1-4-8-16/h1,3-4,7-8,11-12,17,21-22,24-26H,2,5-6,9-10,13-15H2/t21?,22-/m0/s1 CDEXVBIHAFJWIQ-KEKNWZKVSA-N 50007132 1-(Benzylamino-methyl)-3-cyclohexyl-isochroman-5,6-diol::CHEMBL315516 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007132&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320304 103920415 CHEMBL315516 ZINC26575010 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010636 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus 6870 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011699 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2 ZFZPJDFBJFHYIV-UHFFFAOYSA-N 50007692 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL1204189::CHEMBL35057::TIOSPERONE D(2) dopamine receptor Rattus norvegicus 8.4 ChEMBL 10.1021/jm00115a024 10.7270/Q29Z93VX 1683407 Cipollina, JA; Ruediger, EH; New, JS; Wire, ME; Shepherd, TA; Smith, DW; Yevich, JP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55752 103920962 CHEMBL1204189CHEMBL35057 101 ZINC01915508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011700 OC(CCN1C(=O)CC2(CCCC2)CC1=O)CN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H32N4O3S/c29-18(7-10-28-21(30)15-24(16-22(28)31)8-3-4-9-24)17-26-11-13-27(14-12-26)23-19-5-1-2-6-20(19)32-25-23/h1-2,5-6,18,29H,3-4,7-17H2 CDXMFKTZKATLJB-UHFFFAOYSA-N 50007688 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-3-hydroxy-butyl]-8-aza-spiro[4.5]decane-7,9-dione (HCl)::CHEMBL326775 D(2) dopamine receptor Rattus norvegicus 111 ChEMBL 10.1021/jm00115a024 10.7270/Q29Z93VX 1683407 Cipollina, JA; Ruediger, EH; New, JS; Wire, ME; Shepherd, TA; Smith, DW; Yevich, JP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007688&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15068023 103920958 CHEMBL326775 ZINC13650173 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011702 OC1CCC2(C1)CC(=O)N(CCCCN1CCN(CC1)c1nsc3ccccc13)C(=O)C2 InChI=1S/C24H32N4O3S/c29-18-7-8-24(15-18)16-21(30)28(22(31)17-24)10-4-3-9-26-11-13-27(14-12-26)23-19-5-1-2-6-20(19)32-25-23/h1-2,5-6,18,29H,3-4,7-17H2 OXWHAAOUFXSEQT-UHFFFAOYSA-N 50007693 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2-hydroxy-8-aza-spiro[4.5]decane-7,9-dione (HCl)::CHEMBL114451 D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1021/jm00115a024 10.7270/Q29Z93VX 1683407 Cipollina, JA; Ruediger, EH; New, JS; Wire, ME; Shepherd, TA; Smith, DW; Yevich, JP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9825310 103920963 CHEMBL114451 ZINC13650159 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011712 O=C1CCC2(C1)CC(=O)N(CCCCN1CCN(CC1)c1nsc3ccccc13)C(=O)C2 InChI=1S/C24H30N4O3S/c29-18-7-8-24(15-18)16-21(30)28(22(31)17-24)10-4-3-9-26-11-13-27(14-12-26)23-19-5-1-2-6-20(19)32-25-23/h1-2,5-6H,3-4,7-17H2 VJBRVSZHSPYQNJ-UHFFFAOYSA-N 50007694 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-2,7,9-trione (HCl)::CHEMBL115367 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1021/jm00115a024 10.7270/Q29Z93VX 1683407 Cipollina, JA; Ruediger, EH; New, JS; Wire, ME; Shepherd, TA; Smith, DW; Yevich, JP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007694&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15068020 103920964 CHEMBL115367 ZINC13650164 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011719 OC1C(=O)N(CCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)CC11CCCC1 InChI=1S/C24H32N4O3S/c29-20-17-24(9-3-4-10-24)21(30)23(31)28(20)12-6-5-11-26-13-15-27(16-14-26)22-18-7-1-2-8-19(18)32-25-22/h1-2,7-8,21,30H,3-6,9-17H2 JFLFNSMJIVQGSO-UHFFFAOYSA-N 50007690 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-6-hydroxy-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL115486 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm00115a024 10.7270/Q29Z93VX 1683407 Cipollina, JA; Ruediger, EH; New, JS; Wire, ME; Shepherd, TA; Smith, DW; Yevich, JP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007690&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15068025 103920960 CHEMBL115486 ZINC03798527 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011721 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)C1OC(=O)CC11CCCC1 InChI=1S/C24H32N4O3S/c29-20-17-24(9-3-4-10-24)21(31-20)23(30)25-11-5-6-12-27-13-15-28(16-14-27)22-18-7-1-2-8-19(18)32-26-22/h1-2,7-8,21H,3-6,9-17H2,(H,25,30) OKYUOPQSBVIWPC-UHFFFAOYSA-N 50007691 3-Oxo-2-oxa-spiro[4.4]nonane-1-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide (1.4HCl)::CHEMBL321591 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm00115a024 10.7270/Q29Z93VX 1683407 Cipollina, JA; Ruediger, EH; New, JS; Wire, ME; Shepherd, TA; Smith, DW; Yevich, JP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007691&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15068036 103920961 CHEMBL321591 ZINC13650171 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010640 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1 SUHGRZPINGKYNV-GJZGRUSLSA-N 50007129 (1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol::1-Aminomethyl-3-phenyl-isochroman-5,6-diol::A-70108::CHEMBL86931 D(2) dopamine receptor Rattus norvegicus 10200 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122324 103920412 CHEMBL86931 6077 ZINC03787668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010643 OCCCNC[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C19H29NO4/c21-10-4-9-20-12-18-14-7-8-16(22)19(23)15(14)11-17(24-18)13-5-2-1-3-6-13/h7-8,13,17-18,20-23H,1-6,9-12H2/t17?,18-/m0/s1 CUYXSVNDDNBRBL-ZVAWYAOSSA-N 50007131 3-Cyclohexyl-1-[(3-hydroxy-propylamino)-methyl]-isochroman-5,6-diol::CHEMBL85552 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007131&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319988 103920414 CHEMBL85552 ZINC26573613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010647 Oc1ccc2[C@H](CNCC#C)OC(Cc2c1O)C1CCCCC1 InChI=1S/C19H25NO3/c1-2-10-20-12-18-14-8-9-16(21)19(22)15(14)11-17(23-18)13-6-4-3-5-7-13/h1,8-9,13,17-18,20-22H,3-7,10-12H2/t17?,18-/m0/s1 OTQGSZPQJUEZOA-ZVAWYAOSSA-N 50007144 3-Cyclohexyl-1-prop-2-ynylaminomethyl-isochroman-5,6-diol::CHEMBL420788 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007144&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320303 103920427 CHEMBL420788 ZINC26573906 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010648 CN(CC#C)C[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C20H27NO3/c1-3-11-21(2)13-19-15-9-10-17(22)20(23)16(15)12-18(24-19)14-7-5-4-6-8-14/h1,9-10,14,18-19,22-23H,4-8,11-13H2,2H3/t18?,19-/m0/s1 ORJBNDRHLGFVFW-GGYWPGCISA-N 50007142 3-Cyclohexyl-1-[(methyl-prop-2-ynyl-amino)-methyl]-isochroman-5,6-diol::CHEMBL315535 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007142&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320002 103920425 CHEMBL315535 ZINC26569605 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010655 NC[C@@H]1OC(Cc2ccccc2)Cc2c(O)c(O)ccc12 InChI=1S/C17H19NO3/c18-10-16-13-6-7-15(19)17(20)14(13)9-12(21-16)8-11-4-2-1-3-5-11/h1-7,12,16,19-20H,8-10,18H2/t12?,16-/m0/s1 XVBBSQGJSIEXFQ-INSVYWFGSA-N 50007150 1-Aminomethyl-3-benzyl-isochroman-5,6-diol::CHEMBL87910 D(2) dopamine receptor Rattus norvegicus 1470 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320076 103920433 CHEMBL87910 ZINC26575753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010663 NC[C@@H]1OC(COCc2ccccc2)Cc2c(O)c(O)ccc12 InChI=1S/C18H21NO4/c19-9-17-14-6-7-16(20)18(21)15(14)8-13(23-17)11-22-10-12-4-2-1-3-5-12/h1-7,13,17,20-21H,8-11,19H2/t13?,17-/m0/s1 JAZQRIDSKRIHDH-RUINGEJQSA-N 50007153 1-Aminomethyl-3-benzyloxymethyl-isochroman-5,6-diol::CHEMBL86325 D(2) dopamine receptor Rattus norvegicus 386 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007153&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320257 103920436 CHEMBL86325 ZINC26576776 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010672 NC[C@@H]1OC(CCc2ccccc2)Cc2c(O)c(O)ccc12 InChI=1S/C18H21NO3/c19-11-17-14-8-9-16(20)18(21)15(14)10-13(22-17)7-6-12-4-2-1-3-5-12/h1-5,8-9,13,17,20-21H,6-7,10-11,19H2/t13?,17-/m0/s1 KIARRRIAGXQGBT-RUINGEJQSA-N 50007128 1-Aminomethyl-3-phenethyl-isochroman-5,6-diol::CHEMBL84983 D(2) dopamine receptor Rattus norvegicus 670 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007128&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320001 103920411 CHEMBL84983 ZINC26569603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010674 CCCCCCC1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C16H25NO3/c1-2-3-4-5-6-11-9-13-12(15(10-17)20-11)7-8-14(18)16(13)19/h7-8,11,15,18-19H,2-6,9-10,17H2,1H3/t11?,15-/m0/s1 HMYHFTUKXYGDQG-MHTVFEQDSA-N 50007146 1-Aminomethyl-3-hexyl-isochroman-5,6-diol::CHEMBL420972 D(2) dopamine receptor Rattus norvegicus 782 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007146&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320116 103920429 CHEMBL420972 ZINC26573749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010676 NC[C@@H]1OC2(CCCCC2)Cc2c(O)c(O)ccc12 InChI=1S/C15H21NO3/c16-9-13-10-4-5-12(17)14(18)11(10)8-15(19-13)6-2-1-3-7-15/h4-5,13,17-18H,1-3,6-9,16H2/t13-/m0/s1 MWZPAYJAPPEPRS-ZDUSSCGKSA-N 50007145 1-Aminomethyl-isochroman-5,6-diol spirocyclohexane::CHEMBL420604 D(2) dopamine receptor Rattus norvegicus 6680 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007145&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15696487 103920428 CHEMBL420604 ZINC13823830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033950 CCCN1CCC=C2C1CCc1sc(N)nc21 InChI=1S/C13H19N3S/c1-2-7-16-8-3-4-9-10(16)5-6-11-12(9)15-13(14)17-11/h4,10H,2-3,5-8H2,1H3,(H2,14,15) VOPHHPYKMCJUCP-UHFFFAOYSA-N 50007571 6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-2-ylamine::CHEMBL91453 D(2) dopamine receptor Rattus norvegicus 860 ChEMBL 10.1021/jm00113a010 10.7270/Q2V125FC 1680195 Caprathe, BW; Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT; Parvez, M Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14233815 103920841 CHEMBL91453 ZINC13824112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010685 NC[C@@H]1OC(COc2ccccc2)Cc2c(O)c(O)ccc12 InChI=1S/C17H19NO4/c18-9-16-13-6-7-15(19)17(20)14(13)8-12(22-16)10-21-11-4-2-1-3-5-11/h1-7,12,16,19-20H,8-10,18H2/t12?,16-/m0/s1 KOHDNXKBNHHXKQ-INSVYWFGSA-N 50007130 1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol::CHEMBL86576 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007130&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320267 103920413 CHEMBL86576 ZINC26576192 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010686 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)c1ccc(Br)cc1 InChI=1S/C16H16BrNO3/c17-10-3-1-9(2-4-10)14-7-12-11(15(8-18)21-14)5-6-13(19)16(12)20/h1-6,14-15,19-20H,7-8,18H2/t14?,15-/m0/s1 LDLAWZLGWDENOK-LOACHALJSA-N 50007123 1-Aminomethyl-3-(4-bromo-phenyl)-isochroman-5,6-diol::CHEMBL415080 D(2) dopamine receptor Rattus norvegicus 358 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007123&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320092 103920406 CHEMBL415080 ZINC26570699 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50652618 CCCN1CCC=C2C1CCc1sc(N)nc21 InChI=1S/C13H19N3S/c1-2-7-16-8-3-4-9-10(16)5-6-11-12(9)15-13(14)17-11/h4,10H,2-3,5-8H2,1H3,(H2,14,15) VOPHHPYKMCJUCP-UHFFFAOYSA-N 50007571 6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-2-ylamine::CHEMBL91453 D(2) dopamine receptor Rattus norvegicus 2197 ChEMBL 10.1021/jm00113a010 10.7270/Q2V125FC 1680195 Caprathe, BW; Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT; Parvez, M Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14233815 103920841 CHEMBL91453 ZINC13824112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010984 Clc1ccc(CCN[C@@H]2CCCC[C@@H]2N2CCCC2)cc1Cl InChI=1S/C18H26Cl2N2/c19-15-8-7-14(13-16(15)20)9-10-21-17-5-1-2-6-18(17)22-11-3-4-12-22/h7-8,13,17-18,21H,1-6,9-12H2/t17-,18+/m1/s1 NREHOBGKKWFKES-MSOLQXFVSA-N 50007314 CHEMBL104834::[2-(3,4-Dichloro-phenyl)-ethyl]-(2-pyrrolidin-1-yl-cyclohexyl)-amine D(2) dopamine receptor Rattus norvegicus 8514 ChEMBL 10.1021/jm00114a015 10.7270/Q2VX0FGB 1656044 Radesca, L; Bowen, WD; Di Paolo, L; de Costa, BR National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9905985 103920589 CHEMBL104834 ZINC19365786 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013215 CCN1CCC[C@H]1CNC(=O)c1cc(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 QAECXZXKVURFMR-LBPRGKRZSA-N 50007522 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide::5-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2,3-dimethoxybenzamide::CHEMBL289330 D(2) dopamine receptor Rattus norvegicus 0.760000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9907436 103920797 CHEMBL289330 ZINC03780178 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013216 CCN1CCC[C@@H]1CNC(=O)c1c(O)c(CCCF)cc(OC)c1OC InChI=1S/C19H29FN2O4/c1-4-22-10-6-8-14(22)12-21-19(24)16-17(23)13(7-5-9-20)11-15(25-2)18(16)26-3/h11,14,23H,4-10,12H2,1-3H3,(H,21,24)/t14-/m1/s1 CUVDIPGTXCBTQZ-CQSZACIVSA-N 50453046 CHEMBL2114461 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894967 225145823 CHEMBL2114461 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013219 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CCF)cc(OC)c1OC InChI=1S/C18H27FN2O4/c1-4-21-9-5-6-13(21)11-20-18(23)15-16(22)12(7-8-19)10-14(24-2)17(15)25-3/h10,13,22H,4-9,11H2,1-3H3,(H,20,23)/t13-/m0/s1 NCDPKFAUDDDXBP-ZDUSSCGKSA-N 50008786 CHEMBL43506::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-(2-fluoro-ethyl)-2-hydroxy-5,6-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.770 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14910582 103921915 CHEMBL43506 ZINC13821891 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011092 C(CN1CCN(CC1)c1ccccc1)Cc1ccc2ccccc2c1 InChI=1S/C23H26N2/c1-2-10-23(11-3-1)25-17-15-24(16-18-25)14-6-7-20-12-13-21-8-4-5-9-22(21)19-20/h1-5,8-13,19H,6-7,14-18H2 ZDMWBBFQNAAKPP-UHFFFAOYSA-N 50007397 1-(3-Naphthalen-2-yl-propyl)-4-phenyl-piperazine::CHEMBL112037 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00116a003 10.7270/Q2MC8XZR 1662725 Glennon, RA; Yousif, MY; Ismaiel, AM; el-Ashmawy, MB; Herndon, JL; Fischer, JB; Server, AC; Howie, KJ Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15723897 103920672 CHEMBL112037 ZINC13447127 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011097 OC1(CCN(CCCc2ccccc2)CC1)c1ccccc1 InChI=1S/C20H25NO/c22-20(19-11-5-2-6-12-19)13-16-21(17-14-20)15-7-10-18-8-3-1-4-9-18/h1-6,8-9,11-12,22H,7,10,13-17H2 ZZUJERGWKSXINO-UHFFFAOYSA-N 50007398 4-Phenyl-1-(3-phenyl-propyl)-piperidin-4-ol::4-phenyl-1-(3-phenylpropyl)piperidin-4-ol::CHEMBL115508 D(2) dopamine receptor Rattus norvegicus 1250 ChEMBL 10.1021/jm00116a003 10.7270/Q2MC8XZR 1662725 Glennon, RA; Yousif, MY; Ismaiel, AM; el-Ashmawy, MB; Herndon, JL; Fischer, JB; Server, AC; Howie, KJ Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15723894 103920673 CHEMBL115508 ZINC12356051 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011105 C(CCc1ccccc1)CN1CCN(CC1)c1ccccc1 InChI=1S/C20H26N2/c1-3-9-19(10-4-1)11-7-8-14-21-15-17-22(18-16-21)20-12-5-2-6-13-20/h1-6,9-10,12-13H,7-8,11,14-18H2 BGDZXIKVCVQJFR-UHFFFAOYSA-N 50007401 1-Phenyl-4-(4-phenyl-butyl)-piperazine::CHEMBL85879 D(2) dopamine receptor Rattus norvegicus 45 ChEMBL 10.1021/jm00116a003 10.7270/Q2MC8XZR 1662725 Glennon, RA; Yousif, MY; Ismaiel, AM; el-Ashmawy, MB; Herndon, JL; Fischer, JB; Server, AC; Howie, KJ Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007401&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15723883 103920676 CHEMBL85879 ZINC13447108 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011108 C(CCN1CCC(CC1)c1ccccc1)CCc1ccccc1 InChI=1S/C22H29N/c1-4-10-20(11-5-1)12-6-3-9-17-23-18-15-22(16-19-23)21-13-7-2-8-14-21/h1-2,4-5,7-8,10-11,13-14,22H,3,6,9,12,15-19H2 IOOPAUYHVADGIS-UHFFFAOYSA-N 50007396 4-Phenyl-1-(5-phenyl-pentyl)-piperidine::CHEMBL112474 D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm00116a003 10.7270/Q2MC8XZR 1662725 Glennon, RA; Yousif, MY; Ismaiel, AM; el-Ashmawy, MB; Herndon, JL; Fischer, JB; Server, AC; Howie, KJ Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007396&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126229 103920671 CHEMBL112474 ZINC13447117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011115 C(CCc1ccccc1)CN1CCC(CC1)c1ccccc1 InChI=1S/C21H27N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-13,21H,7-8,11,14-18H2 HQGDPZPNAXRCSA-UHFFFAOYSA-N 50007400 4-Phenyl-1-(4-phenyl-butyl)-piperidine::4-Phenyl-1-(4-phenyl-butyl)-piperidine: maleate::CHEMBL1788131::CHEMBL325238 D(2) dopamine receptor Rattus norvegicus 165 ChEMBL 10.1021/jm00116a003 10.7270/Q2MC8XZR 1662725 Glennon, RA; Yousif, MY; Ismaiel, AM; el-Ashmawy, MB; Herndon, JL; Fischer, JB; Server, AC; Howie, KJ Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007400&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3035672 103920675 CHEMBL325238CHEMBL1788131 ZINC02557962 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011116 C(CN1CCC(CC1)c1ccccc1)Cc1ccccc1 InChI=1S/C20H25N/c1-3-8-18(9-4-1)10-7-15-21-16-13-20(14-17-21)19-11-5-2-6-12-19/h1-6,8-9,11-12,20H,7,10,13-17H2 NICAAVHYYGSEJF-UHFFFAOYSA-N 50007393 4-Phenyl-1-(3-phenyl-propyl)-piperidine::CHEMBL112124 D(2) dopamine receptor Rattus norvegicus 335 ChEMBL 10.1021/jm00116a003 10.7270/Q2MC8XZR 1662725 Glennon, RA; Yousif, MY; Ismaiel, AM; el-Ashmawy, MB; Herndon, JL; Fischer, JB; Server, AC; Howie, KJ Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44341349 103920668 CHEMBL112124 ZINC13447114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011119 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1021/jm00116a003 10.7270/Q2MC8XZR 1662725 Glennon, RA; Yousif, MY; Ismaiel, AM; el-Ashmawy, MB; Herndon, JL; Fischer, JB; Server, AC; Howie, KJ Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013220 CCN1CCC[C@@H]1CNC(=O)c1cc(CCF)cc(OC)c1OC InChI=1S/C18H27FN2O3/c1-4-21-9-5-6-14(21)12-20-18(22)15-10-13(7-8-19)11-16(23-2)17(15)24-3/h10-11,14H,4-9,12H2,1-3H3,(H,20,22)/t14-/m1/s1 ARAWZUUSXRTRLM-CQSZACIVSA-N 50453047 CHEMBL2114460 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14910565 225145824 CHEMBL2114460 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013223 CCCc1cc(OC)c(OC)c(c1)C(=O)NC[C@@H]1CCCN1CC InChI=1S/C19H30N2O3/c1-5-8-14-11-16(18(24-4)17(12-14)23-3)19(22)20-13-15-9-7-10-21(15)6-2/h11-12,15H,5-10,13H2,1-4H3,(H,20,22)/t15-/m0/s1 VZDSICGZEIITJX-HNNXBMFYSA-N 50008787 CHEMBL43552::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-5-propyl-benzamide D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008787&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14910585 103921916 CHEMBL43552 ZINC13821893 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013224 CCN1CCC[C@H]1CNC(=O)c1cc(CCCF)cc(OC)c1OC InChI=1S/C19H29FN2O3/c1-4-22-10-6-8-15(22)13-21-19(23)16-11-14(7-5-9-20)12-17(24-2)18(16)25-3/h11-12,15H,4-10,13H2,1-3H3,(H,21,23)/t15-/m0/s1 CRDCKDWZBHLFAS-HNNXBMFYSA-N 50008785 CHEMBL42953::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(3-fluoro-propyl)-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(3-fluoro-propyl)-2,3-dimethoxy-benzamide (FP-epidepride) D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10043596 103921914 CHEMBL42953 ZINC05650383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013225 CCN1CCC[C@H]1CNC(=O)c1cc(CCF)cc(OC)c1OC InChI=1S/C18H27FN2O3/c1-4-21-9-5-6-14(21)12-20-18(22)15-10-13(7-8-19)11-16(23-2)17(15)24-3/h10-11,14H,4-9,12H2,1-3H3,(H,20,22)/t14-/m0/s1 ARAWZUUSXRTRLM-AWEZNQCLSA-N 50008784 CHEMBL288704::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(2-fluoro-ethyl)-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008784&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14910564 103921913 CHEMBL288704 ZINC13821889 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013228 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013229 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013230 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor Rattus norvegicus 0.660000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013231 CCCc1cc(OC)c(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1O InChI=1S/C19H30N2O4/c1-5-8-13-11-15(24-3)18(25-4)16(17(13)22)19(23)20-12-14-9-7-10-21(14)6-2/h11,14,22H,5-10,12H2,1-4H3,(H,20,23)/t14-/m0/s1 XGLIHZCJAFMECG-AWEZNQCLSA-N 50008788 CHEMBL42260::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-5,6-dimethoxy-3-propyl-benzamide D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008788&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668308 103921917 CHEMBL42260 ZINC13821895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013233 CCN1CCC[C@H]1CNC(=O)c1cccc(OC)c1OC InChI=1S/C16H24N2O3/c1-4-18-10-6-7-12(18)11-17-16(19)13-8-5-9-14(20-2)15(13)21-3/h5,8-9,12H,4,6-7,10-11H2,1-3H3,(H,17,19)/t12-/m0/s1 RCZDXFJAMRSBKF-LBPRGKRZSA-N 50007523 CHEMBL295621::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007523&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14416349 103920798 CHEMBL295621 ZINC13820636 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013236 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.990000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013239 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CCCF)cc(OC)c1OC InChI=1S/C19H29FN2O4/c1-4-22-10-6-8-14(22)12-21-19(24)16-17(23)13(7-5-9-20)11-15(25-2)18(16)26-3/h11,14,23H,4-10,12H2,1-3H3,(H,21,24)/t14-/m0/s1 CUVDIPGTXCBTQZ-AWEZNQCLSA-N 50008783 CHEMBL42448::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-(3-fluoro-propyl)-2-hydroxy-5,6-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.250000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008783&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894966 103921912 CHEMBL42448 ZINC06385020 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010001 FC(F)(F)c1nc2c(OCCNCc3ccccc3)cc(Cl)cc2[nH]1 InChI=1S/C17H15ClF3N3O/c18-12-8-13-15(24-16(23-13)17(19,20)21)14(9-12)25-7-6-22-10-11-4-2-1-3-5-11/h1-5,8-9,22H,6-7,10H2,(H,23,24) MMZIPJNBJQJCBM-UHFFFAOYSA-N 50081105 Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine::CHEMBL86504 D(2) dopamine receptor Rattus norvegicus 0.710000 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081105&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9820680 103981159 CHEMBL86504 ZINC03926703 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010003 Clc1cc(OCCNCc2ccccc2)c2[nH]c(=S)[nH]c2c1 InChI=1S/C16H16ClN3OS/c17-12-8-13-15(20-16(22)19-13)14(9-12)21-7-6-18-10-11-4-2-1-3-5-11/h1-5,8-9,18H,6-7,10H2,(H2,19,20,22) HMFWWORRYDWEDS-UHFFFAOYSA-N 50081107 4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazole-2-thione::CHEMBL89037 D(2) dopamine receptor Rattus norvegicus 4.5 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9949531 103981161 CHEMBL89037 ZINC01547101 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010005 S=c1[nH]c2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C16H17N3OS/c21-16-18-13-7-4-8-14(15(13)19-16)20-10-9-17-11-12-5-2-1-3-6-12/h1-8,17H,9-11H2,(H2,18,19,21) IMYFITBNCNWHTL-UHFFFAOYSA-N 50081108 4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazole-2-thione::CHEMBL327782 D(2) dopamine receptor Rattus norvegicus 0.180000 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081108&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817774 103981162 CHEMBL327782 ZINC01547096 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011150 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 3045 ChEMBL 10.1021/jm00105a029 10.7270/Q2GM867T 1671414 Iorio, MA; Frigeni, V; Bowman, ER; Harris, LS; May, EL; Aceto, MD Istituto Superiore di Sanità http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011151 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.2 ChEMBL 10.1021/jm00105a029 10.7270/Q2GM867T 1671414 Iorio, MA; Frigeni, V; Bowman, ER; Harris, LS; May, EL; Aceto, MD Istituto Superiore di Sanità http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011152 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 302 ChEMBL 10.1021/jm00105a029 10.7270/Q2GM867T 1671414 Iorio, MA; Frigeni, V; Bowman, ER; Harris, LS; May, EL; Aceto, MD Istituto Superiore di Sanità http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011154 CCC(=O)O[C@]1(CCN(CCCC(=O)c2ccc(F)cc2)CC1C)c1ccccc1 InChI=1S/C25H30FNO3/c1-3-24(29)30-25(21-8-5-4-6-9-21)15-17-27(18-19(25)2)16-7-10-23(28)20-11-13-22(26)14-12-20/h4-6,8-9,11-14,19H,3,7,10,15-18H2,1-2H3/t19?,25-/m0/s1 REXOMGWVBIKJKZ-BIAFCPFJSA-N 50007421 CHEMBL59245::Propionic acid 1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-3-methyl-4-phenyl-piperidin-4-yl ester D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm00105a029 10.7270/Q2GM867T 1671414 Iorio, MA; Frigeni, V; Bowman, ER; Harris, LS; May, EL; Aceto, MD Istituto Superiore di Sanità http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44301589 103920696 CHEMBL59245 ZINC13860901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011156 CCC(=O)O[C@@]1(CCN(CCCC(=O)c2ccc(F)cc2)C[C@H]1C)c1ccccc1 InChI=1S/C25H30FNO3/c1-3-24(29)30-25(21-8-5-4-6-9-21)15-17-27(18-19(25)2)16-7-10-23(28)20-11-13-22(26)14-12-20/h4-6,8-9,11-14,19H,3,7,10,15-18H2,1-2H3/t19-,25-/m1/s1 REXOMGWVBIKJKZ-KBMIEXCESA-N 50007420 CHEMBL418289::Propionic acid 1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-3-methyl-4-phenyl-piperidin-4-yl ester D(2) dopamine receptor Rattus norvegicus 147 ChEMBL 10.1021/jm00105a029 10.7270/Q2GM867T 1671414 Iorio, MA; Frigeni, V; Bowman, ER; Harris, LS; May, EL; Aceto, MD Istituto Superiore di Sanità http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007420&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44301815 103920695 CHEMBL418289 ZINC29559244 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010259 O[C@@H](COc1ccccc1)CN1CCC(CC1)c1ccc(Oc2ccccc2)cc1 InChI=1S/C26H29NO3/c28-23(20-29-24-7-3-1-4-8-24)19-27-17-15-22(16-18-27)21-11-13-26(14-12-21)30-25-9-5-2-6-10-25/h1-14,22-23,28H,15-20H2/t23-/m1/s1 FXLWBYZTEVJBSX-HSZRJFAPSA-N 50082319 (R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-yl]-propan-2-ol; hydrochloride::CHEMBL554228 D(2) dopamine receptor Rattus norvegicus 4640 ChEMBL 10.1016/s0960-894x(99)00516-8 10.7270/Q2D21Z3B 10571163 Annoura, H; Nakanishi, K; Uesugi, M; Fukunaga, A; Miyajima, A; Tamura-Horikawa, Y; Tamura, S Institute for Bio-Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332705 103982122 CHEMBL554228 ZINC13836164 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011468 O=c1[nH]c2ccc(CCN3CCN(CC3)c3cccc4ccccc34)cc2o1 InChI=1S/C23H23N3O2/c27-23-24-20-9-8-17(16-22(20)28-23)10-11-25-12-14-26(15-13-25)21-7-3-5-18-4-1-2-6-19(18)21/h1-9,16H,10-15H2,(H,24,27) DPNXNSJFFDGJRR-UHFFFAOYSA-N 50007556 6-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-3H-benzooxazol-2-one::CHEMBL55362 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9820887 103920826 CHEMBL55362 ZINC01484352 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011476 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 172 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011479 Cc1sc(N)nc1-c1ccc(CCN2CCN(CC2)c2cccc3ccccc23)cc1 InChI=1S/C26H28N4S/c1-19-25(28-26(27)31-19)22-11-9-20(10-12-22)13-14-29-15-17-30(18-16-29)24-8-4-6-21-5-2-3-7-23(21)24/h2-12H,13-18H2,1H3,(H2,27,28) IBCPOBSZTPUMBP-UHFFFAOYSA-N 50007561 5-Methyl-4-{4-[2-(4-naphthalen-1-yl-piperazin-1-yl)-ethyl]-phenyl}-thiazol-2-ylamine::CHEMBL292201 D(2) dopamine receptor Rattus norvegicus 159 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14726996 103920831 CHEMBL292201 ZINC00607479 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010387 Fc1ccc(cc1)C(=O)CCCN1CCN(CC2CC(=O)c3ccc(F)cc3C2)CC1 InChI=1S/C25H28F2N2O2/c26-21-5-3-19(4-6-21)24(30)2-1-9-28-10-12-29(13-11-28)17-18-14-20-16-22(27)7-8-23(20)25(31)15-18/h3-8,16,18H,1-2,9-15,17H2 MHWRZIBDNNXDFT-UHFFFAOYSA-N 50453055 CHEMBL72649 D(2) dopamine receptor Rattus norvegicus 78 ChEMBL 10.1021/jm00111a046 10.7270/Q2930VPR 1676759 Cortizo, L; Santana, L; Ravina, E; Orallo, F; Fontenla, JA; Castro, E; Calleja, JM; de Ceballos, ML University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453055&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10432606 225145832 CHEMBL72649 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011481 Nc1nc(cs1)-c1ccc(CCN2CCN(CC2)c2cccc3ccccc23)cc1 InChI=1S/C25H26N4S/c26-25-27-23(18-30-25)21-10-8-19(9-11-21)12-13-28-14-16-29(17-15-28)24-7-3-5-20-4-1-2-6-22(20)24/h1-11,18H,12-17H2,(H2,26,27) IHLXCIWXJLTTDK-UHFFFAOYSA-N 50007562 4-{4-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-phenyl}-thiazol-2-ylamine::CHEMBL300849 D(2) dopamine receptor Rattus norvegicus 72 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14726992 103920832 CHEMBL300849 ZINC00596828 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011490 C(Cc1ccc(cc1)-c1csnn1)N1CCN(CC1)c1cccc2ccccc12 InChI=1S/C24H24N4S/c1-2-6-22-20(4-1)5-3-7-24(22)28-16-14-27(15-17-28)13-12-19-8-10-21(11-9-19)23-18-29-26-25-23/h1-11,18H,12-17H2 VFLATHBHSNDSHU-UHFFFAOYSA-N 50007560 1-Naphthalen-1-yl-4-[2-(4-[1,2,3]thiadiazol-4-yl-phenyl)-ethyl]-piperazine::CHEMBL53565 D(2) dopamine receptor Rattus norvegicus 83 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14727030 103920830 CHEMBL53565 ZINC13822244 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011493 O=c1[nH]c(cs1)-c1ccc(CCN2CCN(CC2)c2cccc3ccccc23)cc1 InChI=1S/C25H25N3OS/c29-25-26-23(18-30-25)21-10-8-19(9-11-21)12-13-27-14-16-28(17-15-27)24-7-3-5-20-4-1-2-6-22(20)24/h1-11,18H,12-17H2,(H,26,29) JJQKCJJTQLIHNU-UHFFFAOYSA-N 50007565 4-{4-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-phenyl}-thiazol-2-ol::CHEMBL55055 D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15054215 103920835 CHEMBL55055 ZINC00607480 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011499 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011500 CCN1C(=O)Cc2cc(CCN3CCN(CC3)c3cccc4ccccc34)ccc12 InChI=1S/C26H29N3O/c1-2-29-24-11-10-20(18-22(24)19-26(29)30)12-13-27-14-16-28(17-15-27)25-9-5-7-21-6-3-4-8-23(21)25/h3-11,18H,2,12-17,19H2,1H3 SZIFDVUATXWDDZ-UHFFFAOYSA-N 50007563 1-Ethyl-5-[2-(4-naphthalen-1-yl-piperazin-1-yl)-ethyl]-1,3-dihydro-indol-2-one::CHEMBL56536 D(2) dopamine receptor Rattus norvegicus 81.2 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14581412 103920833 CHEMBL56536 ZINC13822236 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011502 CNc1nc(cs1)-c1ccc(CCN2CCN(CC2)c2cccc3ccccc23)cc1 InChI=1S/C26H28N4S/c1-27-26-28-24(19-31-26)22-11-9-20(10-12-22)13-14-29-15-17-30(18-16-29)25-8-4-6-21-5-2-3-7-23(21)25/h2-12,19H,13-18H2,1H3,(H,27,28) NMRBIVALVIFCPC-UHFFFAOYSA-N 50007564 CHEMBL55806::Methyl-(4-{4-[2-(4-naphthalen-1-yl-piperazin-1-yl)-ethyl]-phenyl}-thiazol-2-yl)-amine D(2) dopamine receptor Rattus norvegicus 155 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14727008 103920834 CHEMBL55806 ZINC13822238 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011503 O=C1Cc2cc(CCN3CCN(CC3)c3cccc4ccccc34)ccc2N1 InChI=1S/C24H25N3O/c28-24-17-20-16-18(8-9-22(20)25-24)10-11-26-12-14-27(15-13-26)23-7-3-5-19-4-1-2-6-21(19)23/h1-9,16H,10-15,17H2,(H,25,28) GEJKYGSJUJTWOZ-UHFFFAOYSA-N 50007559 5-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-1,3-dihydro-indol-2-one::CHEMBL54786 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11176199 103920829 CHEMBL54786 ZINC03782398 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011504 Cc1nc(cs1)-c1ccc(CCN2CCN(CC2)c2cccc3ccccc23)cc1 InChI=1S/C26H27N3S/c1-20-27-25(19-30-20)23-11-9-21(10-12-23)13-14-28-15-17-29(18-16-28)26-8-4-6-22-5-2-3-7-24(22)26/h2-12,19H,13-18H2,1H3 PYMOZSUFJZTWLN-UHFFFAOYSA-N 50007566 1-{2-[4-(2-Methyl-thiazol-4-yl)-phenyl]-ethyl}-4-naphthalen-1-yl-piperazine::CHEMBL54910 D(2) dopamine receptor Rattus norvegicus 108 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14727012 103920836 CHEMBL54910 ZINC13822242 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011508 CC1(C)C(=O)Nc2ccc(CCN3CCN(CC3)c3cccc4ccccc34)cc12 InChI=1S/C26H29N3O/c1-26(2)22-18-19(10-11-23(22)27-25(26)30)12-13-28-14-16-29(17-15-28)24-9-5-7-20-6-3-4-8-21(20)24/h3-11,18H,12-17H2,1-2H3,(H,27,30) YYWPITZZELMSNP-UHFFFAOYSA-N 50007557 3,3-Dimethyl-5-[2-(4-naphthalen-1-yl-piperazin-1-yl)-ethyl]-1,3-dihydro-indol-2-one::CHEMBL294702 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298215 103920827 CHEMBL294702 ZINC13822234 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011510 O=c1[nH]c2ccc(CCN3CCN(CC3)c3cccc4ccccc34)cc2s1 InChI=1S/C23H23N3OS/c27-23-24-20-9-8-17(16-22(20)28-23)10-11-25-12-14-26(15-13-25)21-7-3-5-18-4-1-2-6-19(18)21/h1-9,16H,10-15H2,(H,24,27) ZUYFWNWIYZNXLQ-UHFFFAOYSA-N 50007558 6-[2-(4-Naphthalen-1-yl-piperazin-1-yl)-ethyl]-3H-benzothiazol-2-one::CHEMBL292163 D(2) dopamine receptor Rattus norvegicus 112 ChEMBL 10.1021/jm00110a016 10.7270/Q2Q52NK3 1676427 Lowe, JA; Seeger, TF; Nagel, AA; Howard, HR; Seymour, PA; Heym, JH; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11361267 103920828 CHEMBL292163 ZINC13822232 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011516 CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3 XRYLGRGAWQSVQW-UHFFFAOYSA-N 22872 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methyl-piperazine;maleate::1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine::1-{6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine::CHEMBL64249::CLOROTEPINE (+)::CLOROTEPINE(-)::Clothepin::OCTOCLOTHEPIN,(+)::OCTOCLOTHEPIN,(-)::Octoclothepin::Octoclothepine D(2) dopamine receptor Rattus norvegicus 2.4 ChEMBL 10.1021/jm00111a015 10.7270/Q2KD1WVC 1676758 Bogeso, KP; Liljefors, T; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1238 49846686 CHEMBL64249 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011520 CN1CCN(CC1)[C@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m0/s1 XRYLGRGAWQSVQW-KRWDZBQOSA-N 50007568 1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL303313::OCTOCLOTHEPIN-S D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm00111a015 10.7270/Q2KD1WVC 1676758 Bogeso, KP; Liljefors, T; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12765746 103920838 CHEMBL303313 ZINC19368911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011521 CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m1/s1 XRYLGRGAWQSVQW-QGZVFWFLSA-N 50007567 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL64875::OCTOCLOTHEPIN-R D(2) dopamine receptor Rattus norvegicus 6.6 ChEMBL 10.1021/jm00111a015 10.7270/Q2KD1WVC 1676758 Bogeso, KP; Liljefors, T; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603950 103920837 CHEMBL64875 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010519 CNC[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C17H25NO3/c1-18-10-16-12-7-8-14(19)17(20)13(12)9-15(21-16)11-5-3-2-4-6-11/h7-8,11,15-16,18-20H,2-6,9-10H2,1H3/t15?,16-/m0/s1 CQTDHZQZXNNVLA-LYKKTTPLSA-N 50007125 3-Cyclohexyl-1-methylaminomethyl-isochroman-5,6-diol::CHEMBL315750 D(2) dopamine receptor Rattus norvegicus 724 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007125&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320024 103920408 CHEMBL315750 ZINC26574942 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010522 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCCCC1 InChI=1S/C18H27NO3/c19-11-17-13-8-9-15(20)18(21)14(13)10-16(22-17)12-6-4-2-1-3-5-7-12/h8-9,12,16-17,20-21H,1-7,10-11,19H2/t16?,17-/m0/s1 NYSMWUFTIPGKQH-DJNXLDHESA-N 50007127 1-Aminomethyl-3-cyclooctyl-isochroman-5,6-diol::CHEMBL85689 D(2) dopamine receptor Rattus norvegicus 342 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007127&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320026 103920410 CHEMBL85689 ZINC26574069 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010530 CCCCC1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C14H21NO3/c1-2-3-4-9-7-11-10(13(8-15)18-9)5-6-12(16)14(11)17/h5-6,9,13,16-17H,2-4,7-8,15H2,1H3/t9?,13-/m0/s1 MMVLDBWARAYRHY-NCWAPJAISA-N 50007133 1-Aminomethyl-3-butyl-isochroman-5,6-diol::CHEMBL431220 D(2) dopamine receptor Rattus norvegicus 825 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007133&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320129 103920416 CHEMBL431220 ZINC26574347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010535 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C16H23NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h6-7,10,14-15,18-19H,1-5,8-9,17H2/t14?,15-/m0/s1 BOKASTZDGGZFET-LOACHALJSA-N 50007148 1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol::CHEMBL314459 D(2) dopamine receptor Rattus norvegicus 1120 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007148&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320050 103920431 CHEMBL314459 ZINC26575279 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010546 Oc1ccc2[C@H](CNCC=C)OC(Cc2c1O)C1CCCCC1 InChI=1S/C19H27NO3/c1-2-10-20-12-18-14-8-9-16(21)19(22)15(14)11-17(23-18)13-6-4-3-5-7-13/h2,8-9,13,17-18,20-22H,1,3-7,10-12H2/t17?,18-/m0/s1 NOOMHYKWRAKBNS-ZVAWYAOSSA-N 50007140 1-Allylaminomethyl-3-cyclohexyl-isochroman-5,6-diol::CHEMBL419680 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007140&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320327 103920423 CHEMBL419680 ZINC26577121 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010556 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C20H27NO3/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20/h1-2,11-13,17-18,22-23H,3-10,21H2/t11-,12+,13-,17-,18?,20?/m0/s1 QLJOSZATCBCBDR-UAKDSABFSA-N 50007147 3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol::CHEMBL313530 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007147&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 64638 103920430 CHEMBL313530 ZINC03871344 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010566 NC[C@@H]1OC(CC2CCCC2)Cc2c(O)c(O)ccc12 InChI=1S/C16H23NO3/c17-9-15-12-5-6-14(18)16(19)13(12)8-11(20-15)7-10-3-1-2-4-10/h5-6,10-11,15,18-19H,1-4,7-9,17H2/t11?,15-/m0/s1 LRRXEOSYJLVRAV-MHTVFEQDSA-N 50007149 1-Aminomethyl-3-cyclopentylmethyl-isochroman-5,6-diol::CHEMBL85409 D(2) dopamine receptor Rattus norvegicus 427 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007149&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320378 103920432 CHEMBL85409 ZINC26576518 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010567 CC(C)(C)C1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C14H21NO3/c1-14(2,3)12-6-9-8(11(7-15)18-12)4-5-10(16)13(9)17/h4-5,11-12,16-17H,6-7,15H2,1-3H3/t11-,12?/m0/s1 OOZQGBSETLAPCT-PXYINDEMSA-N 50007126 1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol::CHEMBL82899 D(2) dopamine receptor Rattus norvegicus 8190 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007126&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320053 103920409 CHEMBL82899 ZINC26571262 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011695 OC(CCN1C(=O)CC2(CCC(O)C2)CC1=O)CN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H32N4O4S/c29-17-5-7-24(13-17)14-21(31)28(22(32)15-24)8-6-18(30)16-26-9-11-27(12-10-26)23-19-3-1-2-4-20(19)33-25-23/h1-4,17-18,29-30H,5-16H2 FEPIVRHFKXOYNY-UHFFFAOYSA-N 50007689 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-3-hydroxy-butyl]-2-hydroxy-8-aza-spiro[4.5]decane-7,9-dione (HCl.0.2H2O)::CHEMBL114131 D(2) dopamine receptor Rattus norvegicus 491 ChEMBL 10.1021/jm00115a024 10.7270/Q29Z93VX 1683407 Cipollina, JA; Ruediger, EH; New, JS; Wire, ME; Shepherd, TA; Smith, DW; Yevich, JP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007689&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15068024 103920959 CHEMBL114131 ZINC13650179 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50017550 CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)c1c[nH]c2ccccc12 InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3/t11-,12+,13+ ZNRGQMMCGHDTEI-ITGUQSILSA-N 50108392 (3-ENDO)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL 1H-INDOLE-3-CARBOXYLATE::CHEMBL56564 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(01)00693-x 10.7270/Q20R9PX0 11755351 Iriepa, I; Villasante, FJ; Galvez, E; Labeaga, L; Innerarity, A; Orjales, A Universidad de Alcal£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108392&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TKT 6HIS,2WNC,5OAJ 656665 104003611 CHEMBL56564 C02089 ZINC18130447 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015640 CCCN1CCO[C@@H]2[C@@H]1COc1ccc(O)cc21 InChI=1S/C14H19NO3/c1-2-5-15-6-7-17-14-11-8-10(16)3-4-13(11)18-9-12(14)15/h3-4,8,12,14,16H,2,5-7,9H2,1H3/t12-,14-/m0/s1 YOILXOMTHPUMRG-JSGCOSHPSA-N 50090831 (-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::CHEMBL97424 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00163a068 10.7270/Q2BK1B94 1967318 DeWald, HA; Heffner, TG; Jaen, JC; Lustgarten, DM; McPhail, AT; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090831&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 115107 103989292 CHEMBL97424 952 ZINC26729865 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015642 CCCN(CCC)C1COc2ccc(O)cc2C1 InChI=1S/C15H23NO2/c1-3-7-16(8-4-2)13-9-12-10-14(17)5-6-15(12)18-11-13/h5-6,10,13,17H,3-4,7-9,11H2,1-2H3 COYBCQFIVNQGKW-UHFFFAOYSA-N 50010587 3-Dipropylamino-chroman-6-ol::CHEMBL69414 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00163a068 10.7270/Q2BK1B94 1967318 DeWald, HA; Heffner, TG; Jaen, JC; Lustgarten, DM; McPhail, AT; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86146 103923363 CHEMBL69414 ZINC05647677 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015646 CCCN1CCO[C@H]2[C@H]1COc1ccc(O)cc21 InChI=1S/C14H19NO3/c1-2-5-15-6-7-17-14-11-8-10(16)3-4-13(11)18-9-12(14)15/h3-4,8,12,14,16H,2,5-7,9H2,1H3/t12-,14-/m1/s1 YOILXOMTHPUMRG-TZMCWYRMSA-N 50010586 (+)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(4aR,10aR)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(Racemic)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(trans)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol (PD 128907)::1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::CHEMBL70565::PD 128,907 D(2) dopamine receptor Rattus norvegicus 409 ChEMBL 10.1021/jm00163a068 10.7270/Q2BK1B94 1967318 DeWald, HA; Heffner, TG; Jaen, JC; Lustgarten, DM; McPhail, AT; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6O 7CMV 5311346 103923362 CHEMBL70565 ZINC25726114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015647 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm00163a068 10.7270/Q2BK1B94 1967318 DeWald, HA; Heffner, TG; Jaen, JC; Lustgarten, DM; McPhail, AT; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015650 CN1CCN(CC1)C1=Cc2ccccc2C(=C)c2ccc(Cl)cc12 InChI=1S/C21H21ClN2/c1-15-18-6-4-3-5-16(18)13-21(24-11-9-23(2)10-12-24)20-14-17(22)7-8-19(15)20/h3-8,13-14H,1,9-12H2,2H3 YVKWMORDCBVMMB-UHFFFAOYSA-N 50010592 1-(8-Chloro-5-methylene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL72162 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm00164a053 10.7270/Q2348JCH 1967652 Davis, DA; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010592&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312605 103923367 CHEMBL72162 ZINC26379106 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015653 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 2770 ChEMBL 10.1021/jm00164a053 10.7270/Q2348JCH 1967652 Davis, DA; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015657 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccccc12 InChI=1S/C18H20N4/c1-21-10-12-22(13-11-21)18-14-6-2-3-7-15(14)19-16-8-4-5-9-17(16)20-18/h2-9,19H,10-13H2,1H3 VQHITFFJBFOMBG-UHFFFAOYSA-N 50010591 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL73538 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00164a053 10.7270/Q2348JCH 1967652 Davis, DA; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search WEC 8E9X,8E9W 16103 103923366 CHEMBL73538 ZINC26377671 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015660 CN1CCN(CC1)C1=Cc2ccccc2C(=C(C)C)c2ccc(Cl)cc12 InChI=1S/C23H25ClN2/c1-16(2)23-19-7-5-4-6-17(19)14-22(26-12-10-25(3)11-13-26)21-15-18(24)8-9-20(21)23/h4-9,14-15H,10-13H2,1-3H3 HYAGQWNRZOZWBC-UHFFFAOYSA-N 50010596 1-(8-Chloro-5-isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL73082 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00164a053 10.7270/Q2348JCH 1967652 Davis, DA; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010596&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312870 103923371 CHEMBL73082 ZINC26380875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015661 CN1CCN(CC1)C1=Cc2cc(Cl)ccc2C(=C)c2ccccc12 InChI=1S/C21H21ClN2/c1-15-18-8-7-17(22)13-16(18)14-21(20-6-4-3-5-19(15)20)24-11-9-23(2)10-12-24/h3-8,13-14H,1,9-12H2,2H3 PRRVUGWDILXJOU-UHFFFAOYSA-N 50010595 1-(2-Chloro-5-methylene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL355107 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00164a053 10.7270/Q2348JCH 1967652 Davis, DA; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44379650 103923370 CHEMBL355107 ZINC27892892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015671 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Rattus norvegicus 218 ChEMBL 10.1021/jm00164a053 10.7270/Q2348JCH 1967652 Davis, DA; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015672 CN1CCN(CC1)C1=Cc2ccccc2C(=C)c2ccccc12 InChI=1S/C21H22N2/c1-16-18-8-4-3-7-17(18)15-21(20-10-6-5-9-19(16)20)23-13-11-22(2)12-14-23/h3-10,15H,1,11-14H2,2H3 NBFZVLQBKCNVGZ-UHFFFAOYSA-N 50010598 1-Methyl-4-(5-methylene-5H-dibenzo[a,d]cyclohepten-10-yl)-piperazine::CHEMBL91310 D(2) dopamine receptor Rattus norvegicus 305 ChEMBL 10.1021/jm00164a053 10.7270/Q2348JCH 1967652 Davis, DA; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010598&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323851 103923373 CHEMBL91310 ZINC13738219 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015673 CN1CCN(CC1)C1=Cc2ccccc2C(=C(C)C)c2ccccc12 InChI=1S/C23H26N2/c1-17(2)23-19-9-5-4-8-18(19)16-22(20-10-6-7-11-21(20)23)25-14-12-24(3)13-15-25/h4-11,16H,12-15H2,1-3H3 NJUSHLPQKJYNMD-UHFFFAOYSA-N 50010597 1-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL88870 D(2) dopamine receptor Rattus norvegicus 4750 ChEMBL 10.1021/jm00164a053 10.7270/Q2348JCH 1967652 Davis, DA; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010597&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323876 103923372 CHEMBL88870 ZINC13738222 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015674 CN1CCN(CC1)C1=Cc2cc(Cl)ccc2C(=C(C)C)c2ccccc12 InChI=1S/C23H25ClN2/c1-16(2)23-19-9-8-18(24)14-17(19)15-22(20-6-4-5-7-21(20)23)26-12-10-25(3)11-13-26/h4-9,14-15H,10-13H2,1-3H3 QCJIDMPIJUWNKR-UHFFFAOYSA-N 50010593 1-(2-Chloro-5-isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL328246 D(2) dopamine receptor Rattus norvegicus 5000 ChEMBL 10.1021/jm00164a053 10.7270/Q2348JCH 1967652 Davis, DA; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010593&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323870 103923368 CHEMBL328246 ZINC13738221 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015691 Oc1cccc(c1)C1CCC2CCCCN2C1 InChI=1S/C15H21NO.C2H2O4/c17-15-6-3-4-12(10-15)13-7-8-14-5-1-2-9-16(14)11-13;3-1(4)2(5)6/h3-4,6,10,13-14,17H,1-2,5,7-9,11H2;(H,3,4)(H,5,6) IXLZJCYTLAFFMV-UHFFFAOYSA-N 50452756 CHEMBL2051756 D(2) dopamine receptor Rattus norvegicus 40000 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452756&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70686325 225145739 CHEMBL2051756 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015696 Oc1cccc(c1)[C@H]1CCCN2CCCC12 InChI=1S/C14H19NO/c16-12-5-1-4-11(10-12)13-6-2-8-15-9-3-7-14(13)15/h1,4-5,10,13-14,16H,2-3,6-9H2/t13-,14?/m1/s1 WOXUXMJHVREOKX-KWCCSABGSA-N 50010613 3-(Octahydro-indolizin-8-yl)-phenol::CHEMBL7850 D(2) dopamine receptor Rattus norvegicus 45 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010613&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720757 103923387 CHEMBL7850 ZINC25976231 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015698 Oc1cccc(c1)C1CCCN2CCCC12 InChI=1S/C14H19NO/c16-12-5-1-4-11(10-12)13-6-2-8-15-9-3-7-14(13)15/h1,4-5,10,13-14,16H,2-3,6-9H2 WOXUXMJHVREOKX-UHFFFAOYSA-N 50010616 (+)-3-(Octahydro-indolizin-8-yl)-phenol::(-)-3-(Octahydro-indolizin-8-yl)-phenol::3-(Octahydro-indolizin-8-yl)-phenol::CHEMBL268240::isomer-13-(Octahydro-indolizin-8-yl)-phenol::isomer-23-(Octahydro-indolizin-8-yl)-phenol D(2) dopamine receptor Rattus norvegicus 75 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010616&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720753 103923390 CHEMBL268240 ZINC25979781 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015702 Oc1cccc(c1)[C@@H]1CCCN2CCCC12 InChI=1S/C14H19NO/c16-12-5-1-4-11(10-12)13-6-2-8-15-9-3-7-14(13)15/h1,4-5,10,13-14,16H,2-3,6-9H2/t13-,14?/m0/s1 WOXUXMJHVREOKX-LSLKUGRBSA-N 50010620 3-(Octahydro-indolizin-8-yl)-phenol::CHEMBL8074 D(2) dopamine receptor Rattus norvegicus 170 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010620&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720755 103923394 CHEMBL8074 ZINC25979588 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015703 Oc1cccc(c1)C1CCCN2CCCCC12 InChI=1S/C15H21NO/c17-13-6-3-5-12(11-13)14-7-4-10-16-9-2-1-8-15(14)16/h3,5-6,11,14-15,17H,1-2,4,7-10H2 RUTLNJGVITWMQE-UHFFFAOYSA-N 50010614 3-(Octahydro-quinolizin-1-yl)-phenol::CHEMBL7381::isomer-13-(Octahydro-quinolizin-1-yl)-phenol::isomer-23-(Octahydro-quinolizin-1-yl)-phenol D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720739 103923388 CHEMBL7381 ZINC34133358 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015705 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 3400 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015706 CCCN(CCc1ccsc1)C1CCc2c(O)cccc2C1 InChI=1S/C19H25NOS/c1-2-10-20(11-8-15-9-12-22-14-15)17-6-7-18-16(13-17)4-3-5-19(18)21/h3-5,9,12,14,17,21H,2,6-8,10-11,13H2,1H3 RHRKSVACMIQFDY-UHFFFAOYSA-N 50010621 6-[Propyl-(2-thiophen-3-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL7806 D(2) dopamine receptor Rattus norvegicus 8.8 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010621&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128054 103923395 CHEMBL7806 ZINC05833419 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015707 CCCN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m0/s1 HTSNFXAICLXZMA-ZDUSSCGKSA-N 50010618 (+)-3-(1-Propyl-piperidin-3-yl)-phenol::3-((R)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(-)::CHEMBL7393::cid_202478 D(2) dopamine receptor Rattus norvegicus 23000 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 202478 103923392 CHEMBL7393 ZINC00000393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015708 Oc1cccc(c1)C1=CCCN2CCCCC12 InChI=1S/C15H19NO/c17-13-6-3-5-12(11-13)14-7-4-10-16-9-2-1-8-15(14)16/h3,5-7,11,15,17H,1-2,4,8-10H2 UTPPZLWOQNHIMZ-UHFFFAOYSA-N 50010615 3-(3,6,7,8,9,9a-Hexahydro-4H-quinolizin-1-yl)-phenol::CHEMBL7449 D(2) dopamine receptor Rattus norvegicus 5300 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010615&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720735 103923389 CHEMBL7449 ZINC25974459 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015800 CN1CCc2cccc-3c2[C@@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m0/s1 VMWNQDUVQKEIOC-ZDUSSCGKSA-N 29643 (6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrochloride::(S)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::Apomorphine,(+)::CHEMBL416288::MLS000028867::S(+)-10,11-DIHYDROXYAPORPHINE HYDROCHLORIDE::SMR000058671::US10864248, Compound 1::cid_6852389 D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5RL 5ER4 736083 252614855 CHEMBL416288 ZINC02858765 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015801 CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H23NO3/c1-3-7-21-8-6-13-9-14(24-2)11-15-18(13)16(21)10-12-4-5-17(22)20(23)19(12)15/h4-5,9,11,16,22-23H,3,6-8,10H2,1-2H3/t16-/m1/s1 WNNMRMNAGNMVEW-MRXNPFEDSA-N 50010692 (R)-(-)-2-methoxy-N-npropylnorapomorphine::(R)-2-methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53294 D(2) dopamine receptor Rattus norvegicus 0.170000 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130907 103923438 CHEMBL53294 ZINC00011666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015803 CN1CCc2cc(Cl)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H16ClNO2/c1-19-5-4-10-6-11(18)8-12-15(10)13(19)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,20-21H,4-5,7H2,1H3/t13-/m1/s1 PJHOITVCPYOEFT-CYBMUJFWSA-N 50010693 2-Chloro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL431946 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14659294 103923439 CHEMBL431946 ZINC29481710 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015805 CCCN1CCc2cc(O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO3/c1-2-6-20-7-5-12-8-13(21)10-14-17(12)15(20)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,21-23H,2,5-7,9H2,1H3/t15-/m1/s1 HLRBSTGXOFUEHW-OAHLLOKOSA-N 52987 (6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol;hydrate;hydrobromide::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::CHEMBL288096::MLS000860063::R( )-2,10,11-Trihydroxy-N-propyl-noraporphine hydrobromide hydrate::SMR000326921::cid_23640911 D(2) dopamine receptor Rattus norvegicus 0.053000 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603798 252633121 CHEMBL288096 ZINC13111190 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015808 COc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C18H19NO3/c1-19-6-5-11-7-12(22-2)9-13-16(11)14(19)8-10-3-4-15(20)18(21)17(10)13/h3-4,7,9,14,20-21H,5-6,8H2,1-2H3/t14-/m1/s1 QGJWYJSOGNAUCY-CQSZACIVSA-N 50010697 (R)-(-)-2-methoxyapomorphine::(R)-2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-methoxyapomorphine::CHEMBL53445 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010697&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 195499 103923443 CHEMBL53445 ZINC03646006 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015812 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 0.800000 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015817 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015818 CN1CCc2cc(O)cc-3c2[C@@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO3/c1-18-5-4-10-6-11(19)8-12-15(10)13(18)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,19-21H,4-5,7H2,1H3/t13-/m0/s1 QNBCPLWFVGLFHO-ZDUSSCGKSA-N 50010699 (+)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::CHEMBL54183 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010699&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15627811 103923445 CHEMBL54183 ZINC03874842 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015819 CN1CCc2cc(O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO3/c1-18-5-4-10-6-11(19)8-12-15(10)13(18)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,19-21H,4-5,7H2,1H3/t13-/m1/s1 QNBCPLWFVGLFHO-CYBMUJFWSA-N 50010698 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::CHEMBL19130 D(2) dopamine receptor Rattus norvegicus 0.380000 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010698&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603797 103923444 CHEMBL19130 ZINC01561184 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015820 CN1CCc2cc(Br)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H16BrNO2/c1-19-5-4-10-6-11(18)8-12-15(10)13(19)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,20-21H,4-5,7H2,1H3/t13-/m1/s1 SETZXJXEHHDPBP-CYBMUJFWSA-N 50010696 (R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL276326 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010696&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15627832 103923442 CHEMBL276326 ZINC28220764 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015830 COc1cc2CCN(C)[C@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C18H19NO3/c1-19-6-5-11-7-12(22-2)9-13-16(11)14(19)8-10-3-4-15(20)18(21)17(10)13/h3-4,7,9,14,20-21H,5-6,8H2,1-2H3/t14-/m0/s1 QGJWYJSOGNAUCY-AWEZNQCLSA-N 50010694 2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL301761 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm00168a040 10.7270/Q2K35SMD 1971309 Gao, YG; Baldessarini, RJ; Kula, NS; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010694&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14659271 103923440 CHEMBL301761 ZINC29478807 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015888 CCN1CCCC1CNC(=O)c1cc(Br)ccc1OC InChI=1S/C15H21BrN2O2/c1-3-18-8-4-5-12(18)10-17-15(19)13-9-11(16)6-7-14(13)20-2/h6-7,9,12H,3-5,8,10H2,1-2H3,(H,17,19) QQORREJGDAZEMQ-UHFFFAOYSA-N 50010718 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-benzamide::CHEMBL75447 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010718&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5323852 103923464 CHEMBL75447 ZINC26384767 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015889 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(O)c1OC InChI=1S/C15H21BrN2O4/c1-3-18-6-4-5-9(18)8-17-15(21)12-13(20)10(16)7-11(19)14(12)22-2/h7,9,19-20H,3-6,8H2,1-2H3,(H,17,21)/t9-/m0/s1 MRDDDUTZQYNACV-VIFPVBQESA-N 50010719 3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,5-dihydroxy-6-methoxy-benzamide::CHEMBL77492 D(2) dopamine receptor Rattus norvegicus 1.9 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010719&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9976590 103923465 CHEMBL77492 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015890 CCN1CCC[C@H]1CNC(=O)c1cc(Br)cc2CCOc12 InChI=1S/C16H21BrN2O2/c1-2-19-6-3-4-13(19)10-18-16(20)14-9-12(17)8-11-5-7-21-15(11)14/h8-9,13H,2-7,10H2,1H3,(H,18,20)/t13-/m0/s1 VRMUQJZSWAAYCB-ZDUSSCGKSA-N 50010720 5-Bromo-2,3-dihydro-benzofuran-7-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL301532 D(2) dopamine receptor Rattus norvegicus 7.2 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010720&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14528122 103923466 CHEMBL301532 ZINC29472310 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015891 CCN1CCC[C@H]1CNC(=O)c1cc(Br)cc2OCCOc12 InChI=1S/C16H21BrN2O3/c1-2-19-5-3-4-12(19)10-18-16(20)13-8-11(17)9-14-15(13)22-7-6-21-14/h8-9,12H,2-7,10H2,1H3,(H,18,20)/t12-/m0/s1 HLCGFTMEOUITRD-LBPRGKRZSA-N 50010721 7-Bromo-2,3-dihydro-benzo[1,4]dioxine-5-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL419832 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14762916 103923467 CHEMBL419832 ZINC26397004 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015892 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015893 CCN1CCCC1CNC(=O)c1cc(Br)c(OC)cc1OC InChI=1S/C16H23BrN2O3/c1-4-19-7-5-6-11(19)10-18-16(20)12-8-13(17)15(22-3)9-14(12)21-2/h8-9,11H,4-7,10H2,1-3H3,(H,18,20) YDOSDFAGGFOMLV-UHFFFAOYSA-N 50010723 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,4-dimethoxy-benzamide::CHEMBL74970 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010723&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13505099 103923469 CHEMBL74970 ZINC26388910 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015895 COc1cc(Br)cc(C(=O)NC2CCN(Cc3ccccc3)CC2)c1OC InChI=1S/C21H25BrN2O3/c1-26-19-13-16(22)12-18(20(19)27-2)21(25)23-17-8-10-24(11-9-17)14-15-6-4-3-5-7-15/h3-7,12-13,17H,8-11,14H2,1-2H3,(H,23,25) SZYKUFQJFLQMPU-UHFFFAOYSA-N 50007514 CHEMBL75842::N-(1-Benzyl-piperidin-4-yl)-5-bromo-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15167710 103920789 CHEMBL75842 ZINC13820634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015896 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015897 CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(OC)c1OC InChI=1S/C16H24N2O4/c1-4-18-9-5-6-11(18)10-17-16(20)14-12(19)7-8-13(21-2)15(14)22-3/h7-8,11,19H,4-6,9-10H2,1-3H3,(H,17,20)/t11-/m0/s1 DQDAHRKHWVTGOB-NSHDSACASA-N 50010724 CHEMBL305916::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 8.8 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14416355 103923470 CHEMBL305916 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015898 CCN1CCCC1CNC(=O)c1cc(Br)cc(O)c1OC InChI=1S/C15H21BrN2O3/c1-3-18-6-4-5-11(18)9-17-15(20)12-7-10(16)8-13(19)14(12)21-2/h7-8,11,19H,3-6,9H2,1-2H3,(H,17,20) UVEHPRQRFSJENI-UHFFFAOYSA-N 50010727 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-3-hydroxy-2-methoxy-benzamide::CHEMBL76266 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010727&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14762910 103923473 CHEMBL76266 ZINC26385148 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015899 CCN1CCCC1CNC(=O)c1cc(Br)cc(OC)c1O InChI=1S/C15H21BrN2O3/c1-3-18-6-4-5-11(18)9-17-15(20)12-7-10(16)8-13(21-2)14(12)19/h7-8,11,19H,3-6,9H2,1-2H3,(H,17,20) UDVCHWOEHQSXMW-UHFFFAOYSA-N 50010725 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-methoxy-benzamide::CHEMBL307491 D(2) dopamine receptor Rattus norvegicus 8210 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010725&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14762914 103923471 CHEMBL307491 ZINC26384761 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015900 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 WGLPSCZHULDZSS-JTQLQIEISA-N 50007517 (S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-5,6-dimethoxybenzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-5,6-dimethoxy-benzamide::CHEMBL76402 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977478 103920792 CHEMBL76402 ZINC03776019 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015901 COc1cccc(C(=O)NC2CC3CCC(C2)N3Cc2ccccc2)c1OC InChI=1S/C23H28N2O3/c1-27-21-10-6-9-20(22(21)28-2)23(26)24-17-13-18-11-12-19(14-17)25(18)15-16-7-4-3-5-8-16/h3-10,17-19H,11-15H2,1-2H3,(H,24,26) PCIWCYUKRZFCMF-UHFFFAOYSA-N 50010728 CHEMBL75876::N-(8-Benzyl-8-aza-bicyclo[3.2.1]oct-3-yl)-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.7 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010728&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3065828 103923474 CHEMBL75876 ZINC04214580 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015902 CCN1CCCC1CNC(=O)c1cccc(OC)c1OC InChI=1S/C16H24N2O3/c1-4-18-10-6-7-12(18)11-17-16(19)13-8-5-9-14(20-2)15(13)21-3/h5,8-9,12H,4,6-7,10-11H2,1-3H3,(H,17,19) RCZDXFJAMRSBKF-UHFFFAOYSA-N 50010726 CHEMBL75887::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 52 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5323845 103923472 CHEMBL75887 ZINC26380389 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50017012 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50017024 CCCN(CCC)[C@H]1CCc2nn3ccccc3c2C1 InChI=1S/C17H25N3/c1-3-10-19(11-4-2)14-8-9-16-15(13-14)17-7-5-6-12-20(17)18-16/h5-7,12,14H,3-4,8-11,13H2,1-2H3/t14-/m0/s1 PWWITWFCENNJEP-AWEZNQCLSA-N 50116767 CHEMBL310867::Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indazol-2-yl-amine D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116767&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10084583 104010406 CHEMBL310867 ZINC13817114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50022428 CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)ccc1OC InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 CANPFCFJURGKAX-JTQLQIEISA-N 50012961 (-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::CHEMBL267723::N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide (IBZM)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide( (S)-(-)IBZM) D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1016/j.bmcl.2003.08.063 10.7270/Q27M07BC 14592497 Baldwin, RM; Fu, X; Kula, NS; Baldessarini, RJ; Amici, L; Innis, RB; Tamagnan, GD Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 107995 103925209 CHEMBL267723 ZINC03786360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50018582 Oc1ccc2CC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m1/s1 DWUAAOIZQFTYQP-MRXNPFEDSA-N 50061669 (R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL134807::CHEMBL64553 D(2) dopamine receptor Rattus norvegicus 0.200000 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378389 103957219 CHEMBL134807CHEMBL64553 ZINC13527706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50019078 CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H23NO3/c1-3-7-21-8-6-13-9-14(24-2)11-15-18(13)16(21)10-12-4-5-17(22)20(23)19(12)15/h4-5,9,11,16,22-23H,3,6-8,10H2,1-2H3/t16-/m1/s1 WNNMRMNAGNMVEW-MRXNPFEDSA-N 50010692 (R)-(-)-2-methoxy-N-npropylnorapomorphine::(R)-2-methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53294 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm00174a002 10.7270/Q2G15ZS3 2147956 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130907 103923438 CHEMBL53294 ZINC00011666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50019080 CCCN1CCc2cc(N)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H22N2O2/c1-2-6-21-7-5-12-8-13(20)10-14-17(12)15(21)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,22-23H,2,5-7,9,20H2,1H3/t15-/m1/s1 GBWRVNBURCRHGS-OAHLLOKOSA-N 50013060 (R)-2-amino-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Amino-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL107041 D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1021/jm00174a002 10.7270/Q2G15ZS3 2147956 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013060&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14728697 103925283 CHEMBL107041 ZINC26849692 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50019084 CCCN1CCc2cc(O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO3/c1-2-6-20-7-5-12-8-13(21)10-14-17(12)15(20)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,21-23H,2,5-7,9H2,1H3/t15-/m1/s1 HLRBSTGXOFUEHW-OAHLLOKOSA-N 52987 (6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol;hydrate;hydrobromide::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::CHEMBL288096::MLS000860063::R( )-2,10,11-Trihydroxy-N-propyl-noraporphine hydrobromide hydrate::SMR000326921::cid_23640911 D(2) dopamine receptor Rattus norvegicus 0.320000 ChEMBL 10.1021/jm00174a002 10.7270/Q2G15ZS3 2147956 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603798 252633121 CHEMBL288096 ZINC13111190 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50019085 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm00174a002 10.7270/Q2G15ZS3 2147956 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50019089 CCCN1CCc2cc(F)cc-3c2[C@H]1Cc1ccc2OCOc2c-31 InChI=1S/C20H20FNO2/c1-2-6-22-7-5-13-8-14(21)10-15-18(13)16(22)9-12-3-4-17-20(19(12)15)24-11-23-17/h3-4,8,10,16H,2,5-7,9,11H2,1H3/t16-/m1/s1 QLNBXWPJNSJICB-MRXNPFEDSA-N 50013062 11-fluoro-7-propyl-(6aR)-6a,7,8,9-tetrahydro-6H-benzo[de][1,3]dioxolo[5',4':5,6]benzo[g]quinoline::CHEMBL106886 D(2) dopamine receptor Rattus norvegicus 98 ChEMBL 10.1021/jm00174a002 10.7270/Q2G15ZS3 2147956 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013062&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14728694 103925285 CHEMBL106886 ZINC26839205 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50019091 CCCN1CCc2cc(N)cc-3c2[C@H]1Cc1ccc2OCOc2c-31 InChI=1S/C20H22N2O2/c1-2-6-22-7-5-13-8-14(21)10-15-18(13)16(22)9-12-3-4-17-20(19(12)15)24-11-23-17/h3-4,8,10,16H,2,5-7,9,11,21H2,1H3/t16-/m1/s1 RZOTXAGRCRSXDN-MRXNPFEDSA-N 50013063 7-propyl-(6aR)-6a,7,8,9-tetrahydro-6H-benzo[de][1,3]dioxolo[5',4':5,6]benzo[g]quinolin-11-amine::CHEMBL107519 D(2) dopamine receptor Rattus norvegicus 704 ChEMBL 10.1021/jm00174a002 10.7270/Q2G15ZS3 2147956 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013063&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14728692 103925286 CHEMBL107519 ZINC26841502 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50019092 CCCN1CCc2cc(F)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H20FNO2/c1-2-6-21-7-5-12-8-13(20)10-14-17(12)15(21)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,22-23H,2,5-7,9H2,1H3/t15-/m1/s1 TVIUJNLDORXPPC-OAHLLOKOSA-N 50013061 (R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL106622 D(2) dopamine receptor Rattus norvegicus 0.071000 ChEMBL 10.1021/jm00174a002 10.7270/Q2G15ZS3 2147956 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013061&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131213 103925284 CHEMBL106622 ZINC26841490 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50019094 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 67 ChEMBL 10.1021/jm00174a002 10.7270/Q2G15ZS3 2147956 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50019095 CCCN1CCc2cc(Br)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H20BrNO2/c1-2-6-21-7-5-12-8-13(20)10-14-17(12)15(21)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,22-23H,2,5-7,9H2,1H3/t15-/m1/s1 NZSGOEUDQMTJJY-OAHLLOKOSA-N 50013059 (R)-2-bromo-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Bromo-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL322574 D(2) dopamine receptor Rattus norvegicus 0.890000 ChEMBL 10.1021/jm00174a002 10.7270/Q2G15ZS3 2147956 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Research Biochemicals Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013059&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25053021 103925282 CHEMBL322574 ZINC26841496 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015692 CCCN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m0/s1 HTSNFXAICLXZMA-ZDUSSCGKSA-N 50010618 (+)-3-(1-Propyl-piperidin-3-yl)-phenol::3-((R)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(-)::CHEMBL7393::cid_202478 D(2) dopamine receptor Rattus norvegicus 98 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 202478 103923392 CHEMBL7393 ZINC00000393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015693 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025853 CN1CCc2cc(Cl)c(O)cc2C2C1CCc1ccccc21 InChI=1S/C19H20ClNO/c1-21-9-8-13-10-16(20)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-17(19)21/h2-5,10-11,17,19,22H,6-9H2,1H3 DMJWENQHWZZWDF-UHFFFAOYSA-N 50017815 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL59139::trans-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol D(2) dopamine receptor Rattus norvegicus 4115.0 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9861622 103929068 CHEMBL59139 ZINC08586471 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025854 CN1CCc2cc(Cl)c(O)cc2[C@H]2[C@H]1CCc1ccccc21 InChI=1S/C19H20ClNO/c1-21-9-8-13-10-16(20)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-17(19)21/h2-5,10-11,17,19,22H,6-9H2,1H3/t17-,19+/m1/s1 DMJWENQHWZZWDF-MJGOQNOKSA-N 50010715 (6aS,13bS)11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL58422::trans-(+) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol D(2) dopamine receptor Rattus norvegicus 3046 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010715&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14787977 103923461 CHEMBL58422 ZINC29562295 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025857 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 648.0 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025861 CN1CCc2cc(Cl)c(O)cc2[C@H]2[C@@H]1CCc1ccccc21 InChI=1S/C19H20ClNO/c1-21-9-8-13-10-16(20)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-17(19)21/h2-5,10-11,17,19,22H,6-9H2,1H3/t17-,19-/m0/s1 DMJWENQHWZZWDF-HKUYNNGSSA-N 50010711 (6aR,13bS )11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL56666::cis-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::cis-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol D(2) dopamine receptor Rattus norvegicus 9070 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010711&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14787976 103923457 CHEMBL56666 ZINC08586471 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025863 COc1cc2[C@@H]3[C@H](CCc4ccccc34)N(C)CCc2cc1O InChI=1S/C20H23NO2/c1-21-10-9-14-11-18(22)19(23-2)12-16(14)20-15-6-4-3-5-13(15)7-8-17(20)21/h3-6,11-12,17,20,22H,7-10H2,1-2H3/t17-,20+/m0/s1 PFFDGIPVWUVXJJ-FXAWDEMLSA-N 50017817 12-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-11-ol::CHEMBL294215 D(2) dopamine receptor Rattus norvegicus 6400 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15069443 103929070 CHEMBL294215 ZINC29563728 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025865 CN1CCc2cc(O)c(O)cc2[C@@H]2[C@@H]1CCc1ccccc21 InChI=1S/C19H21NO2/c1-20-9-8-13-10-17(21)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-16(19)20/h2-5,10-11,16,19,21-22H,6-9H2,1H3/t16-,19+/m0/s1 AWVUOGSYHGHVNB-QFBILLFUSA-N 50017816 7-Methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalene-11,12-diol::CHEMBL56100 D(2) dopamine receptor Rattus norvegicus 2414 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300069 103929069 CHEMBL56100 ZINC29554139 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025867 CN1CCc2cc(O)c(O)cc2[C@H]2[C@@H]1CCc1ccccc21 InChI=1S/C19H21NO2/c1-20-9-8-13-10-17(21)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-16(19)20/h2-5,10-11,16,19,21-22H,6-9H2,1H3/t16-,19-/m0/s1 AWVUOGSYHGHVNB-LPHOPBHVSA-N 50017819 7-Methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalene-11,12-diol::CHEMBL301003 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299993 103929072 CHEMBL301003 ZINC29549773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025868 CN1CCc2ccc(O)cc2[C@@H]2[C@@H]1CCc1ccccc21 InChI=1S/C19H21NO/c1-20-11-10-14-6-8-15(21)12-17(14)19-16-5-3-2-4-13(16)7-9-18(19)20/h2-6,8,12,18-19,21H,7,9-11H2,1H3/t18-,19+/m0/s1 ZLMLFAVUUTUWRO-RBUKOAKNSA-N 50017820 7-Methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL294221 D(2) dopamine receptor Rattus norvegicus 7873.0 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017820&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11208237 103929073 CHEMBL294221 ZINC29558446 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025869 CN1CCc2cc(C)c(O)cc2[C@@H]2[C@@H]1CCc1ccccc21 InChI=1S/C20H23NO/c1-13-11-15-9-10-21(2)18-8-7-14-5-3-4-6-16(14)20(18)17(15)12-19(13)22/h3-6,11-12,18,20,22H,7-10H2,1-2H3/t18-,20+/m0/s1 QRMYWIZKOVBILG-AZUAARDMSA-N 50017818 7,11-Dimethyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL58205 D(2) dopamine receptor Rattus norvegicus 1505 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15069446 103929071 CHEMBL58205 ZINC29563731 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025872 COc1cc2CCN(C)[C@H]3CCc4ccccc4[C@@H]3c2cc1O InChI=1S/C20H23NO2/c1-21-10-9-14-11-19(23-2)18(22)12-16(14)20-15-6-4-3-5-13(15)7-8-17(20)21/h3-6,11-12,17,20,22H,7-10H2,1-2H3/t17-,20+/m0/s1 JJXGGSUCGLJFTO-FXAWDEMLSA-N 50017821 12-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-11-ol::CHEMBL292451 D(2) dopamine receptor Rattus norvegicus 2477 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017821&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15069442 103929074 CHEMBL292451 ZINC29558437 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025873 COc1cc2[C@H]3[C@H](CCc4ccccc34)N(C)CCc2cc1O InChI=1S/C20H23NO2/c1-21-10-9-14-11-18(22)19(23-2)12-16(14)20-15-6-4-3-5-13(15)7-8-17(20)21/h3-6,11-12,17,20,22H,7-10H2,1-2H3/t17-,20-/m0/s1 PFFDGIPVWUVXJJ-PXNSSMCTSA-N 50017822 12-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-11-ol::CHEMBL442740 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299917 103929075 CHEMBL442740 ZINC29552291 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025874 CN1CCc2cc(Cl)c(O)cc2[C@@H]2[C@@H]1CCc1ccccc21 InChI=1S/C19H20ClNO/c1-21-9-8-13-10-16(20)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-17(19)21/h2-5,10-11,17,19,22H,6-9H2,1H3/t17-,19+/m0/s1 DMJWENQHWZZWDF-PKOBYXMFSA-N 50004823 (6aS,13bR)-11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::(6aS,13bR)-11-chloro-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepin-12-ol::11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL298406::Ecopipam::SCH 39166::trans-(-) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol D(2) dopamine receptor Rattus norvegicus 514 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 107930 103918370 CHEMBL298406 3304 ZINC00003897 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025879 CN1CCc2cc(Cl)c(O)cc2[C@@H]2[C@H]1CCc1ccccc21 InChI=1S/C19H20ClNO/c1-21-9-8-13-10-16(20)18(22)11-15(13)19-14-5-3-2-4-12(14)6-7-17(19)21/h2-5,10-11,17,19,22H,6-9H2,1H3/t17-,19-/m1/s1 DMJWENQHWZZWDF-IEBWSBKVSA-N 50010712 (6aR,13bR)11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL294012::cis-(+) 11-Chloro-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol D(2) dopamine receptor Rattus norvegicus 16317 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010712&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6101909 103923458 CHEMBL294012 ZINC29555292 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025882 COc1cc2CCN(C)[C@H]3CCc4ccccc4[C@H]3c2cc1O InChI=1S/C20H23NO2/c1-21-10-9-14-11-19(23-2)18(22)12-16(14)20-15-6-4-3-5-13(15)7-8-17(20)21/h3-6,11-12,17,20,22H,7-10H2,1-2H3/t17-,20-/m0/s1 JJXGGSUCGLJFTO-PXNSSMCTSA-N 50017823 11-Methoxy-7-methyl-5,6a,7,8,9,13b-hexahydro-6H-7-aza-benzo[6,7]cyclohepta[1,2-a]naphthalen-12-ol::CHEMBL294186 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00128a038 10.7270/Q2VQ31P4 2666667 Berger, JG; Chang, WK; Clader, JW; Hou, D; Chipkin, RE; McPhail, AT Schering-Plough Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299940 103929076 CHEMBL294186 ZINC29556435 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015694 CCCN(CCc1ccsc1)C1CCc2c(O)cccc2C1 InChI=1S/C19H25NOS/c1-2-10-20(11-8-15-9-12-22-14-15)17-6-7-18-16(13-17)4-3-5-19(18)21/h3-5,9,12,14,17,21H,2,6-8,10-11,13H2,1H3 RHRKSVACMIQFDY-UHFFFAOYSA-N 50010621 6-[Propyl-(2-thiophen-3-yl-ethyl)-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL7806 D(2) dopamine receptor Rattus norvegicus 0.620000 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010621&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128054 103923395 CHEMBL7806 ZINC05833419 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025021 NC(=O)c1ccc2[C@@H](CCN3CCC(=CC3)c3c[nH]c4c(F)cccc34)OCCc2c1 InChI=1S/C25H26FN3O2/c26-22-3-1-2-20-21(15-28-24(20)22)16-6-10-29(11-7-16)12-8-23-19-5-4-18(25(27)30)14-17(19)9-13-31-23/h1-6,14-15,23,28H,7-13H2,(H2,27,30)/t23-/m1/s1 PNTQCYZWFHYKJG-HSZRJFAPSA-N 50451852 CHEMBL1159649 D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46905266 225145496 CHEMBL1159649 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025023 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3ccc(F)c4ccoc34)OCCc2c1 InChI=1S/C25H25FN2O3/c26-22-4-3-20(24-21(22)9-14-31-24)16-5-10-28(11-6-16)12-7-23-19-2-1-18(25(27)29)15-17(19)8-13-30-23/h1-5,9,14-15,23H,6-8,10-13H2,(H2,27,29) IVJVVSGUEHDXJN-UHFFFAOYSA-N 50451853 CHEMBL2112307 D(2) dopamine receptor Rattus norvegicus 52 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50451853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50451853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9802224 225145497 CHEMBL2112307 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50024000 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1021/jm00124a024 10.7270/Q23B5Z48 2522993 Harrold, MW; Wallace, RA; Farooqui, T; Wallace, LJ; Uretsky, N; Miller, DD Ohio State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025152 Clc1cncc(n1)N1CCNCC1 InChI=1S/C8H11ClN4/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13/h5-6,10H,1-4H2 CJAWPFJGFFNXQI-UHFFFAOYSA-N 50017452 2-chloro-6-piperazin-1-ylpyrazine::6'-Chloro-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl::6'-Chloro-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl(MK-212)::CHEMBL269521::L-630,571::MK 212::MK-212 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017452&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 107992 103928720 CHEMBL269521 165 ZINC01571800 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025155 CC(C)Oc1ccccc1N1CCNCC1 InChI=1S/C13H20N2O/c1-11(2)16-13-6-4-3-5-12(13)15-9-7-14-8-10-15/h3-6,11,14H,7-10H2,1-2H3 QJULELIONYLITF-UHFFFAOYSA-N 50017448 1-(2-Isopropoxy-phenyl)-piperazine::CHEMBL9669 D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017448&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10944016 103928716 CHEMBL9669 ZINC26001539 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025162 CCc1ccccc1N1CCNCC1 InChI=1S/C12H18N2/c1-2-11-5-3-4-6-12(11)14-9-7-13-8-10-14/h3-6,13H,2,7-10H2,1H3 LMQFWBCKQMNEEH-UHFFFAOYSA-N 50017453 1-(2-Ethyl-phenyl)-piperazine::CHEMBL9467 D(2) dopamine receptor Rattus norvegicus 449.0 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2736460 103928721 CHEMBL9467 ZINC02168450 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025164 CCCc1ccccc1N1CCNCC1 InChI=1S/C13H20N2/c1-2-5-12-6-3-4-7-13(12)15-10-8-14-9-11-15/h3-4,6-7,14H,2,5,8-11H2,1H3 FHIDPEUFJOUCRS-UHFFFAOYSA-N 50017451 1-(2-Propyl-phenyl)-piperazine::CHEMBL9870 D(2) dopamine receptor Rattus norvegicus 379 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017451&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10774576 103928719 CHEMBL9870 ZINC26002737 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025165 CC(C)c1ccccc1N1CCNCC1 InChI=1S/C13H20N2/c1-11(2)12-5-3-4-6-13(12)15-9-7-14-8-10-15/h3-6,11,14H,7-10H2,1-2H3 JQQVFOBGUYOMQP-UHFFFAOYSA-N 50017450 1-(2-Isopropyl-phenyl)-piperazine::CHEMBL276156 D(2) dopamine receptor Rattus norvegicus 111 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017450&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3608822 103928718 CHEMBL276156 ZINC03716182 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025169 Clc1ccccc1N1CCNCC1 InChI=1S/C10H13ClN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2 PWZDJIUQHUGFRJ-UHFFFAOYSA-N 50001901 1-(2-Chloro-phenyl)-piperazine::CHEMBL9841 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001901&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 415628 103916268 CHEMBL9841 ZINC00015872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025174 Oc1ccccc1N1CCNCC1 InChI=1S/C10H14N2O/c13-10-4-2-1-3-9(10)12-7-5-11-6-8-12/h1-4,11,13H,5-8H2 UORNTHBBLYBAJJ-UHFFFAOYSA-N 50017456 2-Piperazin-1-yl-phenol::CHEMBL266250 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70530 103928724 CHEMBL266250 ZINC00157416 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025183 Fc1cccc(c1)N1CCNCC1 InChI=1S/C10H13FN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2 KIFCSMQTGWVMOD-UHFFFAOYSA-N 50017455 1-(3-Fluoro-phenyl)-piperazine::CHEMBL269784 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017455&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 77418 103928723 CHEMBL269784 ZINC02529848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025185 CCCCOc1ccccc1N1CCNCC1 InChI=1S/C14H22N2O/c1-2-3-12-17-14-7-5-4-6-13(14)16-10-8-15-9-11-16/h4-7,15H,2-3,8-12H2,1H3 YNPHKRWUIFAKLL-UHFFFAOYSA-N 50017460 1-(2-Butoxy-phenyl)-piperazine::CHEMBL9452 D(2) dopamine receptor Rattus norvegicus 244 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017460&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14479837 103928728 CHEMBL9452 ZINC25997855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025187 [O-][N+](=O)c1cccc(c1)N1CCNCC1 InChI=1S/C10H13N3O2/c14-13(15)10-3-1-2-9(8-10)12-6-4-11-5-7-12/h1-3,8,11H,4-7H2 LHHZRIYUOZPKSG-UHFFFAOYSA-N 50017449 1-(3-Nitro-phenyl)-piperazine::CHEMBL267153 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017449&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2760216 103928717 CHEMBL267153 ZINC04244898 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025206 N#Cc1ccccc1N1CCNCC1 InChI=1S/C11H13N3/c12-9-10-3-1-2-4-11(10)14-7-5-13-6-8-14/h1-4,13H,5-8H2 FRICBZWJFIRJOB-UHFFFAOYSA-N 50017458 2-Piperazin-1-yl-benzonitrile::CHEMBL275943 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2735875 103928726 CHEMBL275943 ZINC02390001 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025209 CCOc1ccccc1N1CCNCC1 InChI=1S/C12H18N2O/c1-2-15-12-6-4-3-5-11(12)14-9-7-13-8-10-14/h3-6,13H,2,7-10H2,1H3 FBQIUSDQWOLCNY-UHFFFAOYSA-N 50017454 1-(2-Ethoxy-phenyl)-piperazine::CHEMBL273923 D(2) dopamine receptor Rattus norvegicus 144 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017454&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 83357 103928722 CHEMBL273923 ZINC00120262 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023031 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm00171a017 10.7270/Q23J3BXF 2391685 Lannoye, GS; Moerlein, SM; Parkinson, D; Welch, MJ Washington University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025234 CCCCc1ccccc1N1CCNCC1 InChI=1S/C14H22N2/c1-2-3-6-13-7-4-5-8-14(13)16-11-9-15-10-12-16/h4-5,7-8,15H,2-3,6,9-12H2,1H3 XJZVCNGBKRTGFO-UHFFFAOYSA-N 50017459 1-(2-Butyl-phenyl)-piperazine::CHEMBL9921 D(2) dopamine receptor Rattus norvegicus 841 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14479835 103928727 CHEMBL9921 ZINC26002752 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025235 Cc1ccccc1N1CCNCC1 InChI=1S/C11H16N2/c1-10-4-2-3-5-11(10)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 WICKLEOONJPMEQ-UHFFFAOYSA-N 50001903 1-o-Tolyl-piperazine::CHEMBL9746 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001903&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91965 103916270 CHEMBL9746 ZINC00066076 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025239 FC(F)(F)c1cccc(c1)N1CCNCC1 InChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2 KKIMDKMETPPURN-UHFFFAOYSA-N 50007406 1-(3-(trifluoromethyl)phenyl)piperazine::1-(3-Trifluoromethyl-phenyl)-piperazine::1-(3-Trifluoromethyl-phenyl)-piperazine(TFMPP)::CHEMBL274866::TFMPP D(2) dopamine receptor Rattus norvegicus 530 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007406&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4296 103920681 CHEMBL274866 ZINC00056464 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025244 C1CN(CCN1)c1ccccc1 InChI=1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2 YZTJYBJCZXZGCT-UHFFFAOYSA-N 50001898 1-Phenyl-piperazine::CHEMBL9434::PHENYLPIPERAZINE D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001898&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search VU9 7FMY 7096 103916265 CHEMBL9434 ZINC00120271 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025246 COc1ccccc1N1CCNCC1 InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 VNZLQLYBRIOLFZ-UHFFFAOYSA-N 50001862 (N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl)-piperazine::1-(2-Methoxy-phenyl)-piperazine::2-METHOXYPHENYLPIPERAZINE::4-(2-Methoxy-phenyl)-piperazin-1-ium::CHEMBL9666 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1346 103916229 CHEMBL9666 280 ZINC00012687 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025251 Fc1ccccc1N1CCNCC1 InChI=1S/C10H13FN2/c11-9-3-1-2-4-10(9)13-7-5-12-6-8-13/h1-4,12H,5-8H2 IVTZRJKKXSKXKO-UHFFFAOYSA-N 50017457 1-(2-Fluoro-phenyl)-piperazine::CHEMBL9429 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70529 103928725 CHEMBL9429 ZINC00155125 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025266 Clc1cccc(c1)N1CCNCC1 InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2 VHFVKMTVMIZMIK-UHFFFAOYSA-N 50001915 1-(3-chlorophenyl)piperazine::CHEMBL478::m-Chlorophenylpiperazine::mCPP D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00125a020 10.7270/Q2HD7TNH 2565400 Martin, GE; Elgin, RJ; Mathiasen, JR; Davis, CB; Kesslick, JM; Baldy, WJ; Shank, RP; DiStefano, DL; Fedde, CL; Scott, MK McNeil Pharmaceutical and Janssen Research Foundation Worldwide http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001915&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1355 103916282 10588 CHEMBL478 142 C11738 ZINC00004285 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025397 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 2770 ChEMBL 10.1021/jm00130a006 10.7270/Q27W6B5D 2571728 Rupard, JH; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025398 CN1CCN(CC1)C1=Cc2ccccc2C(=C(C)C)c2ccc(Cl)cc12 InChI=1S/C23H25ClN2/c1-16(2)23-19-7-5-4-6-17(19)14-22(26-12-10-25(3)11-13-26)21-15-18(24)8-9-20(21)23/h4-9,14-15H,10-13H2,1-3H3 HYAGQWNRZOZWBC-UHFFFAOYSA-N 50010596 1-(8-Chloro-5-isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL73082 D(2) dopamine receptor Rattus norvegicus 4750 ChEMBL 10.1021/jm00130a006 10.7270/Q27W6B5D 2571728 Rupard, JH; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010596&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312870 103923371 CHEMBL73082 ZINC26380875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025402 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccccc12 InChI=1S/C18H20N4/c1-21-10-12-22(13-11-21)18-14-6-2-3-7-15(14)19-16-8-4-5-9-17(16)20-18/h2-9,19H,10-13H2,1H3 VQHITFFJBFOMBG-UHFFFAOYSA-N 50010591 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL73538 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00130a006 10.7270/Q27W6B5D 2571728 Rupard, JH; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search WEC 8E9X,8E9W 16103 103923366 CHEMBL73538 ZINC26377671 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025403 C\C=C1\c2ccccc2C=C(N2CCN(C)CC2)c2cc(Cl)ccc12 InChI=1S/C22H23ClN2/c1-3-18-19-7-5-4-6-16(19)14-22(25-12-10-24(2)11-13-25)21-15-17(23)8-9-20(18)21/h3-9,14-15H,10-13H2,1-2H3/b18-3- GPGQEGGSDSKZFR-ZUWFHJRGSA-N 50017517 1-(8-Chloro-5-ethylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL308843 D(2) dopamine receptor Rattus norvegicus 6970 ChEMBL 10.1021/jm00130a006 10.7270/Q27W6B5D 2571728 Rupard, JH; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312603 103928785 CHEMBL308843 ZINC26378860 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025407 CN1CCN(CC1)C1=Cc2ccccc2C(=C)c2ccc(Cl)cc12 InChI=1S/C21H21ClN2/c1-15-18-6-4-3-5-16(18)13-21(24-11-9-23(2)10-12-24)20-14-17(22)7-8-19(15)20/h3-8,13-14H,1,9-12H2,2H3 YVKWMORDCBVMMB-UHFFFAOYSA-N 50010592 1-(8-Chloro-5-methylene-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL72162 D(2) dopamine receptor Rattus norvegicus 305 ChEMBL 10.1021/jm00130a006 10.7270/Q27W6B5D 2571728 Rupard, JH; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010592&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312605 103923367 CHEMBL72162 ZINC26379106 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025409 CC1c2ccccc2C=C(N2CCN(C)CC2)c2cc(Cl)ccc12 InChI=1S/C21H23ClN2/c1-15-18-6-4-3-5-16(18)13-21(24-11-9-23(2)10-12-24)20-14-17(22)7-8-19(15)20/h3-8,13-15H,9-12H2,1-2H3 ASIRPKXJTMFOPA-UHFFFAOYSA-N 50017518 1-(8-Chloro-5-methyl-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL72220 D(2) dopamine receptor Rattus norvegicus 2650 ChEMBL 10.1021/jm00130a006 10.7270/Q27W6B5D 2571728 Rupard, JH; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312604 103928786 CHEMBL72220 ZINC26378866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025413 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Rattus norvegicus 218 ChEMBL 10.1021/jm00130a006 10.7270/Q27W6B5D 2571728 Rupard, JH; de Paulis, T; Janowsky, A; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023249 CN1CCc2cccc-3c2[C@@H]1Cc1cccc(O)c-31 InChI=1S/C17H17NO/c1-18-9-8-11-4-2-6-13-16(11)14(18)10-12-5-3-7-15(19)17(12)13/h2-7,14,19H,8-10H2,1H3/t14-/m0/s1 PCGXWSCASZVBJT-AWEZNQCLSA-N 50016005 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL157879 D(2) dopamine receptor Rattus norvegicus 2242 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016005&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370629 103927686 CHEMBL157879 ZINC27706848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023254 CN1CCc2cccc-3c2[C@@H]1Cc1c(Br)ccc(O)c-31 InChI=1S/C17H16BrNO/c1-19-8-7-10-3-2-4-11-16(10)14(19)9-12-13(18)5-6-15(20)17(11)12/h2-6,14,20H,7-9H2,1H3/t14-/m0/s1 YDXYUMUNNLVNQU-AWEZNQCLSA-N 50016008 8-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL346017 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016008&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370645 103927689 CHEMBL346017 ZINC27655914 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023257 CN1CCc2cccc-3c2[C@H]1Cc1c(Br)ccc(O)c-31 InChI=1S/C17H16BrNO/c1-19-8-7-10-3-2-4-11-16(10)14(19)9-12-13(18)5-6-15(20)17(11)12/h2-6,14,20H,7-9H2,1H3/t14-/m1/s1 YDXYUMUNNLVNQU-CQSZACIVSA-N 50016010 8-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL155833 D(2) dopamine receptor Rattus norvegicus 449.0 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016010&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370749 103927691 CHEMBL155833 ZINC27656786 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023260 CN1CCc2cccc-3c2[C@@H]1Cc1ccc(Br)c(O)c-31 InChI=1S/C17H16BrNO/c1-19-8-7-10-3-2-4-12-15(10)14(19)9-11-5-6-13(18)17(20)16(11)12/h2-6,14,20H,7-9H2,1H3/t14-/m0/s1 LOSIOYLXOVSGIE-AWEZNQCLSA-N 50016009 10-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL345822 D(2) dopamine receptor Rattus norvegicus 2930 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016009&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370718 103927690 CHEMBL345822 ZINC27706040 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023262 CN1CCc2cccc-3c2[C@H]1Cc1c(Br)cc(Br)c(O)c-31 InChI=1S/C17H15Br2NO/c1-20-6-5-9-3-2-4-10-15(9)14(20)7-11-12(18)8-13(19)17(21)16(10)11/h2-4,8,14,21H,5-7H2,1H3/t14-/m1/s1 RAIOTDNIRNEUDH-CQSZACIVSA-N 50016012 8,10-Dibromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL155883 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016012&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370643 103927693 CHEMBL155883 ZINC27656783 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023263 CN1CCc2cccc-3c2[C@H]1Cc1c(Cl)ccc(O)c-31 InChI=1S/C17H16ClNO/c1-19-8-7-10-3-2-4-11-16(10)14(19)9-12-13(18)5-6-15(20)17(11)12/h2-6,14,20H,7-9H2,1H3/t14-/m1/s1 SZKXJANEEVRYQY-CQSZACIVSA-N 50016006 8-Chloro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL153960 D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016006&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370651 103927687 CHEMBL153960 ZINC27656344 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023264 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023268 COc1cccc2C[C@@H]3N(C)CCc4cccc(c34)-c12 InChI=1S/C18H19NO/c1-19-10-9-12-5-3-7-14-17(12)15(19)11-13-6-4-8-16(20-2)18(13)14/h3-8,15H,9-11H2,1-2H3/t15-/m0/s1 HJSGUUPPOBQDHU-HNNXBMFYSA-N 50016014 11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL155246 D(2) dopamine receptor Rattus norvegicus 829 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016014&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370646 103927695 CHEMBL155246 ZINC27656090 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023269 CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C17H17NO/c1-18-9-8-11-4-2-6-13-16(11)14(18)10-12-5-3-7-15(19)17(12)13/h2-7,14,19H,8-10H2,1H3/t14-/m1/s1 PCGXWSCASZVBJT-CQSZACIVSA-N 50016013 (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL119455::R-(-)-11-hydroxy-aporphine D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016013&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015045 103927694 CHEMBL119455 ZINC00002530 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023270 COc1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 InChI=1S/C18H19NO/c1-19-10-9-12-5-3-7-14-17(12)15(19)11-13-6-4-8-16(20-2)18(13)14/h3-8,15H,9-11H2,1-2H3/t15-/m1/s1 HJSGUUPPOBQDHU-OAHLLOKOSA-N 50016007 (R)-11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::11-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL117841 D(2) dopamine receptor Rattus norvegicus 2162 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016007&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13994412 103927688 CHEMBL117841 ZINC13757611 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023272 COc1ccc2C[C@@H]3N(C)CCc4cc5OCOc5c(c34)-c2c1O InChI=1S/C19H19NO4/c1-20-6-5-11-8-14-19(24-9-23-14)17-15(11)12(20)7-10-3-4-13(22-2)18(21)16(10)17/h3-4,8,12,21H,5-7,9H2,1-2H3/t12-/m0/s1 LODGIKWNLDQZBM-LBPRGKRZSA-N 50016018 (S)-11-methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-12-ol::11-Methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-12-ol (Bulbocapnine)::Bulbocapnine::CHEMBL157912 D(2) dopamine receptor Rattus norvegicus 14047 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016018&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12441 103927699 CHEMBL157912 C09367 ZINC00000103 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023273 CCCN1CCC[C@@H]2Cc3nc(N)ncc3C[C@@H]12 InChI=1S/C14H22N4/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12/h9-10,13H,2-8H2,1H3,(H2,15,16,17)/t10-,13-/m1/s1 TUFADSGTJUOBEH-ZWNOBZJWSA-N 50016017 (5aR,9aR)-6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine::(5aR,9aR)-6-propyl-5,5a,6,7,8,9,9a,10-octahydropyrido[2,3-g]quinazolin-2-amine::6-Propyl-5,5a,6,7,8,9,9a,10-octahydro-pyrido[2,3-g]quinazolin-2-ylamine(Quinelorane)::CHEMBL155731::Quinelorane::Quinerolane D(2) dopamine receptor Rattus norvegicus 151 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016017&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57242 103927698 CHEMBL155731 954 ZINC00005041 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023276 CN1CCc2cccc-3c2[C@H]1Cc1ccc(Cl)c(O)c-31 InChI=1S/C17H16ClNO/c1-19-8-7-10-3-2-4-12-15(10)14(19)9-11-5-6-13(18)17(20)16(11)12/h2-6,14,20H,7-9H2,1H3/t14-/m1/s1 QWRGYVDBJAIMPS-CQSZACIVSA-N 50016016 10-Chloro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL345907 D(2) dopamine receptor Rattus norvegicus 803 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016016&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370725 103927697 CHEMBL345907 ZINC27709590 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023278 CN1CCc2cccc-3c2[C@@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m0/s1 VMWNQDUVQKEIOC-ZDUSSCGKSA-N 29643 (6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrochloride::(S)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::Apomorphine,(+)::CHEMBL416288::MLS000028867::S(+)-10,11-DIHYDROXYAPORPHINE HYDROCHLORIDE::SMR000058671::US10864248, Compound 1::cid_6852389 D(2) dopamine receptor Rattus norvegicus 680 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5RL 5ER4 736083 252614855 CHEMBL416288 ZINC02858765 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023279 COc1ccc2C[C@H]3N(C)CCc4cccc(c34)-c2c1O InChI=1S/C18H19NO2/c1-19-9-8-11-4-3-5-13-16(11)14(19)10-12-6-7-15(21-2)18(20)17(12)13/h3-7,14,20H,8-10H2,1-2H3/t14-/m1/s1 DZUOQMBJJSBONO-CQSZACIVSA-N 50016019 10-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol(apocideine)::CHEMBL154709 D(2) dopamine receptor Rattus norvegicus 2080 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12545 103927700 CHEMBL154709 ZINC02033971 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025466 CCCNC1CCc2[nH]ncc2C1 InChI=1S/C10H17N3/c1-2-5-11-9-3-4-10-8(6-9)7-12-13-10/h7,9,11H,2-6H2,1H3,(H,12,13) PYXYUOJSCYNCKM-UHFFFAOYSA-N 50017539 CHEMBL80414::Propyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine D(2) dopamine receptor Rattus norvegicus 65 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017539&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14539719 103928807 CHEMBL80414 ZINC26466659 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025468 CSCCCNC1CCc2[nH]ncc2C1 InChI=1S/C11H19N3S/c1-15-6-2-5-12-10-3-4-11-9(7-10)8-13-14-11/h8,10,12H,2-7H2,1H3,(H,13,14) QUJDNNNGGPPYGI-UHFFFAOYSA-N 50017540 (3-Methylsulfanyl-propyl)-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine::CHEMBL310820 D(2) dopamine receptor Rattus norvegicus 2030 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017540&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14539723 103928808 CHEMBL310820 ZINC26466489 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025475 C(Cc1cccs1)NC1CCc2[nH]ncc2C1 InChI=1S/C13H17N3S/c1-2-12(17-7-1)5-6-14-11-3-4-13-10(8-11)9-15-16-13/h1-2,7,9,11,14H,3-6,8H2,(H,15,16) JBGKPAYHRKFYTB-UHFFFAOYSA-N 50017545 (4,5,6,7-Tetrahydro-2H-indazol-5-yl)-(2-thiophen-2-yl-ethyl)-amine::CHEMBL311366 D(2) dopamine receptor Rattus norvegicus 9160 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14539722 103928813 CHEMBL311366 ZINC26473361 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025476 CCCCN(CCC)C1CCc2[nH]ncc2C1 InChI=1S/C14H25N3/c1-3-5-9-17(8-4-2)13-6-7-14-12(10-13)11-15-16-14/h11,13H,3-10H2,1-2H3,(H,15,16) SMDLVEZTAYYBNM-UHFFFAOYSA-N 50017541 Butyl-propyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine::CHEMBL78548 D(2) dopamine receptor Rattus norvegicus 330 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017541&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14539725 103928809 CHEMBL78548 ZINC26480597 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025477 C(Cc1ccccc1)NC1CCc2[nH]ncc2C1 InChI=1S/C15H19N3/c1-2-4-12(5-3-1)8-9-16-14-6-7-15-13(10-14)11-17-18-15/h1-5,11,14,16H,6-10H2,(H,17,18) OVLLSQWJAWLJFE-UHFFFAOYSA-N 50017548 CHEMBL81400::Phenethyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine D(2) dopamine receptor Rattus norvegicus 15310 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14539721 103928816 CHEMBL81400 ZINC26486749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025478 CCCN(CCc1cccs1)C1CCc2[nH]ncc2C1 InChI=1S/C16H23N3S/c1-2-8-19(9-7-15-4-3-10-20-15)14-5-6-16-13(11-14)12-17-18-16/h3-4,10,12,14H,2,5-9,11H2,1H3,(H,17,18) PMFQVFIYEWDCCD-UHFFFAOYSA-N 50017547 CHEMBL421512::Propyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-(2-thiophen-2-yl-ethyl)-amine D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017547&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44316823 103928815 CHEMBL421512 ZINC26471392 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025479 CCNC1CCc2[nH]ncc2C1 InChI=1S/C9H15N3/c1-2-10-8-3-4-9-7(5-8)6-11-12-9/h6,8,10H,2-5H2,1H3,(H,11,12) DDFOVLJCDZCIIF-UHFFFAOYSA-N 50017544 CHEMBL77421::Ethyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine D(2) dopamine receptor Rattus norvegicus 610 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14539718 103928812 CHEMBL77421 ZINC26400640 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025480 CCCN(CCc1ccccc1)C1CCc2[nH]ncc2C1 InChI=1S/C18H25N3/c1-2-11-21(12-10-15-6-4-3-5-7-15)17-8-9-18-16(13-17)14-19-20-18/h3-7,14,17H,2,8-13H2,1H3,(H,19,20) ANIKEXZTCGXTKJ-UHFFFAOYSA-N 50017542 CHEMBL80437::Phenethyl-propyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017542&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44316827 103928810 CHEMBL80437 ZINC26473373 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025484 CCCNC1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13) FASDKYOPVNHBLU-UHFFFAOYSA-N 50017550 CHEMBL76399::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine (Pramipexole, PPX)::Pramipexole D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017550&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 4885 103928818 CHEMBL76399 ZINC03831352 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025485 CCCN(C)C1CCc2[nH]ncc2C1 InChI=1S/C11H19N3/c1-3-6-14(2)10-4-5-11-9(7-10)8-12-13-11/h8,10H,3-7H2,1-2H3,(H,12,13) UICRRSDXFBSSOI-UHFFFAOYSA-N 50017546 CHEMBL311225::Methyl-propyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine D(2) dopamine receptor Rattus norvegicus 1233 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017546&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20546768 103928814 CHEMBL311225 ZINC26466559 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025487 CCCN(CCCSC)C1CCc2[nH]ncc2C1 InChI=1S/C14H25N3S/c1-3-7-17(8-4-9-18-2)13-5-6-14-12(10-13)11-15-16-14/h11,13H,3-10H2,1-2H3,(H,15,16) KMCVLDJICNZCPD-UHFFFAOYSA-N 50017551 (3-Methylsulfanyl-propyl)-propyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine::CHEMBL80206 D(2) dopamine receptor Rattus norvegicus 310 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017551&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44316485 103928819 CHEMBL80206 ZINC26468277 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025489 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Rattus norvegicus 1.6 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023283 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023284 CN1CCc2cccc-3c2[C@@H]1Cc1cc(Br)cc(O)c-31 InChI=1S/C17H16BrNO/c1-19-6-5-10-3-2-4-13-16(10)14(19)8-11-7-12(18)9-15(20)17(11)13/h2-4,7,9,14,20H,5-6,8H2,1H3/t14-/m0/s1 KHTGEMLTFUDITR-AWEZNQCLSA-N 50016015 9-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL157735 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016015&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370719 103927696 CHEMBL157735 ZINC27706044 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023285 CN1CCc2cccc-3c2[C@H]1Cc1ccc(Br)c(O)c-31 InChI=1S/C17H16BrNO/c1-19-8-7-10-3-2-4-12-15(10)14(19)9-11-5-6-13(18)17(20)16(11)12/h2-6,14,20H,7-9H2,1H3/t14-/m1/s1 LOSIOYLXOVSGIE-CQSZACIVSA-N 50016011 (R)-10-bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::10-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL155884 D(2) dopamine receptor Rattus norvegicus 664.0 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016011&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370644 103927692 CHEMBL155884 ZINC27656785 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50023286 CN1CCc2cccc-3c2[C@H]1Cc1cc(Br)cc(O)c-31 InChI=1S/C17H16BrNO/c1-19-6-5-10-3-2-4-13-16(10)14(19)8-11-7-12(18)9-15(20)17(11)13/h2-4,7,9,14,20H,5-6,8H2,1H3/t14-/m1/s1 KHTGEMLTFUDITR-CQSZACIVSA-N 50016020 9-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL154989 D(2) dopamine receptor Rattus norvegicus 2579 ChEMBL 10.1021/jm00164a022 10.7270/Q2XS5TCP 2405158 Schaus, JM; Titus, RD; Foreman, MM; Mason, NR; Truex, LL Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370706 103927701 CHEMBL154989 ZINC27655165 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50025490 CCCCNC1CCc2[nH]ncc2C1 InChI=1S/C11H19N3/c1-2-3-6-12-10-4-5-11-9(7-10)8-13-14-11/h8,10,12H,2-7H2,1H3,(H,13,14) XIWDNPJISURRAQ-UHFFFAOYSA-N 50017549 Butyl-(4,5,6,7-tetrahydro-2H-indazol-5-yl)-amine::CHEMBL307076 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00130a027 10.7270/Q2445KGF 2571732 McQuaid, LA; Latz, JE; Clemens, JA; Fuller, RW; Wong, DT; Mason, NR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14539720 103928817 CHEMBL307076 ZINC26404280 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030072 COc1ccc(cc1OC)[C@H](O)[C@@H](C)N1CCN(CC1)c1cccccc1=O InChI=1S/C22H28N2O4/c1-16(22(26)17-9-10-20(27-2)21(15-17)28-3)23-11-13-24(14-12-23)18-7-5-4-6-8-19(18)25/h4-10,15-16,22,26H,11-14H2,1-3H3/t16-,22-/m1/s1 VHWWMFMKKRWURA-OPAMFIHVSA-N 50026172 2-{4-[2-(3,4-Dimethoxy-phenyl)-2-hydroxy-1-methyl-ethyl]-piperazin-1-yl}-cyclohepta-2,4,6-trienone::2-{4-[2-Hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-ethyl]-piperazin-1-yl}-cyclohepta-2,4,6-trienone::CHEMBL57437 D(2) dopamine receptor Rattus norvegicus 1050 ChEMBL 10.1021/jm00152a004 10.7270/Q2N29VZH 3950903 Bagli, J; Bogri, T; Voith, K; Lee, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13298570 103935906 CHEMBL57437 ZINC29562721 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030073 COc1ccc(cc1OC)C(O)CN1CCN(CC1)c1cccccc1=O InChI=1S/C21H26N2O4.ClH/c1-26-20-9-8-16(14-21(20)27-2)19(25)15-22-10-12-23(13-11-22)17-6-4-3-5-7-18(17)24;/h3-9,14,19,25H,10-13,15H2,1-2H3;1H UIOUCVPFPQUSAS-UHFFFAOYSA-N 50452265 CHEMBL2115477 D(2) dopamine receptor Rattus norvegicus 1500 ChEMBL 10.1021/jm00152a004 10.7270/Q2N29VZH 3950903 Bagli, J; Bogri, T; Voith, K; Lee, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452265&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13298563 225145632 CHEMBL2115477 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030074 COc1ccc(cc1OC)[C@H](O)CN1CCN(CC1)c1cccccc1=O InChI=1S/C21H26N2O4/c1-26-20-9-8-16(14-21(20)27-2)19(25)15-22-10-12-23(13-11-22)17-6-4-3-5-7-18(17)24/h3-9,14,19,25H,10-13,15H2,1-2H3/t19-/m1/s1 SGEKLKJQLHJVDK-LJQANCHMSA-N 50452267 Ciladopa D(2) dopamine receptor Rattus norvegicus 2200 ChEMBL 10.1021/jm00152a004 10.7270/Q2N29VZH 3950903 Bagli, J; Bogri, T; Voith, K; Lee, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452267&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133371 225145634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030075 COc1ccc(cc1OC)[C@@H](O)CN1CCN(CC1)c1cccccc1=O InChI=1S/C21H26N2O4/c1-26-20-9-8-16(14-21(20)27-2)19(25)15-22-10-12-23(13-11-22)17-6-4-3-5-7-18(17)24/h3-9,14,19,25H,10-13,15H2,1-2H3/t19-/m0/s1 SGEKLKJQLHJVDK-IBGZPJMESA-N 50452266 CHEMBL2115071 D(2) dopamine receptor Rattus norvegicus 16590 ChEMBL 10.1021/jm00152a004 10.7270/Q2N29VZH 3950903 Bagli, J; Bogri, T; Voith, K; Lee, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452266&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13298564 225145633 CHEMBL2115071 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030086 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Rattus norvegicus 0.532 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030121 COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CC(C)(CC2C1)c1ccccc1 InChI=1S/C23H28ClN3O2/c1-23(15-6-4-3-5-7-15)13-17-10-16(8-9-27(17)14-23)26-22(28)18-11-19(24)20(25)12-21(18)29-2/h3-7,11-12,16-17H,8-10,13-14,25H2,1-2H3,(H,26,28) CNZZVIOBKWRMHA-UHFFFAOYSA-N 50020152 4-Amino-5-chloro-2-methoxy-N-(2-methyl-2-phenyl-octahydro-indolizin-7-yl)-benzamide::CHEMBL45531 D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm00117a008 10.7270/Q2X92985 2900897 King, FD; Hadley, MS; McClelland, CM Beecham Pharmaceuticals Research Division http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020152&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14127577 103931075 CHEMBL45531 ZINC36093050 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029143 CN1C[C@H](c2ccc(O)c(O)c2)c2cccc(N)c2C1 InChI=1S/C16H18N2O2/c1-18-8-12(10-5-6-15(19)16(20)7-10)11-3-2-4-14(17)13(11)9-18/h2-7,12,19-20H,8-9,17H2,1H3/t12-/m1/s1 ODIYTWXTFQEXKZ-GFCCVEGCSA-N 50452157 CHEMBL2092951 D(2) dopamine receptor Rattus norvegicus 99100 ChEMBL 10.1021/jm00367a006 10.7270/Q21J9BBG 6317860 Dandridge, PA; Kaiser, C; Brenner, M; Gaitanopoulos, D; Davis, LD; Webb, RL; Foley, JJ; Sarau, HM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452157&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70695507 225145591 CHEMBL2092951 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030161 OCCN1CCN(Cc2ccc([nH]2)-c2ccc(F)cc2)CC1 InChI=1S/C17H22FN3O/c18-15-3-1-14(2-4-15)17-6-5-16(19-17)13-21-9-7-20(8-10-21)11-12-22/h1-6,19,22H,7-13H2 NDOBIDITDVWVQA-UHFFFAOYSA-N 50020171 2-{4-[5-(4-Fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-piperazin-1-yl}-ethanol::CHEMBL299283 D(2) dopamine receptor Rattus norvegicus 31000 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198559 103931088 CHEMBL299283 ZINC29568525 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030162 Fc1ccc(cc1)N1CCN(Cc2ccc([nH]2)-c2ccc(F)cc2)CC1 InChI=1S/C21H21F2N3/c22-17-3-1-16(2-4-17)21-10-7-19(24-21)15-25-11-13-26(14-12-25)20-8-5-18(23)6-9-20/h1-10,24H,11-15H2 XYUUPGPKUVPULM-UHFFFAOYSA-N 50020172 1-(4-Fluoro-phenyl)-4-[5-(4-fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-piperazine::CHEMBL57901 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198556 103931089 CHEMBL57901 ZINC29569127 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030164 COc1ccccc1N1CCN(Cc2ccc([nH]2)-c2c(F)cccc2F)CC1 InChI=1S/C22H23F2N3O/c1-28-21-8-3-2-7-20(21)27-13-11-26(12-14-27)15-16-9-10-19(25-16)22-17(23)5-4-6-18(22)24/h2-10,25H,11-15H2,1H3 YDLINVBRACGETC-UHFFFAOYSA-N 50020173 1-[5-(2,6-Difluoro-phenyl)-1H-pyrrol-2-ylmethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL56548 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198550 103931090 CHEMBL56548 ZINC29560333 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030165 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030167 COc1ccccc1N1CCN(Cc2ccc(-c3ccccc3)n2-c2ccccc2)CC1 InChI=1S/C28H29N3O/c1-32-28-15-9-8-14-27(28)30-20-18-29(19-21-30)22-25-16-17-26(23-10-4-2-5-11-23)31(25)24-12-6-3-7-13-24/h2-17H,18-22H2,1H3 RQSSEWYSSIWKJW-UHFFFAOYSA-N 50020175 1-(1,5-Diphenyl-1H-pyrrol-2-ylmethyl)-4-(2-methoxy-phenyl)-piperazine::CHEMBL300993 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020175&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198554 103931092 CHEMBL300993 ZINC29564196 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030169 CCS(=O)(=O)c1ccc(OC)c(c1)-c1ccc(CN2CCN(CC2)c2ccccc2OC)[nH]1 InChI=1S/C25H31N3O4S/c1-4-33(29,30)20-10-12-24(31-2)21(17-20)22-11-9-19(26-22)18-27-13-15-28(16-14-27)23-7-5-6-8-25(23)32-3/h5-12,17,26H,4,13-16,18H2,1-3H3 BGDYEYPXORXJHR-UHFFFAOYSA-N 50019956 1-[5-(5-Ethanesulfonyl-2-methoxy-phenyl)-1H-pyrrol-2-ylmethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL60648 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900360 103930879 CHEMBL60648 ZINC29566166 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030171 Fc1ccc(cc1)C(=O)C1CCN(Cc2ccc([nH]2)-c2ccc(F)cc2)CC1 InChI=1S/C23H22F2N2O/c24-19-5-1-16(2-6-19)22-10-9-21(26-22)15-27-13-11-18(12-14-27)23(28)17-3-7-20(25)8-4-17/h1-10,18,26H,11-15H2 OYMIKHJIDQRXLJ-UHFFFAOYSA-N 50020176 (4-Fluoro-phenyl)-{1-[5-(4-fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-piperidin-4-yl}-methanone::CHEMBL59171 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020176&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198562 103931093 CHEMBL59171 ZINC29569129 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030173 Fc1ccc(cc1)-c1ccc(CN2CCN(CC2)c2cccc3ccoc23)[nH]1 InChI=1S/C23H22FN3O/c24-19-6-4-17(5-7-19)21-9-8-20(25-21)16-26-11-13-27(14-12-26)22-3-1-2-18-10-15-28-23(18)22/h1-10,15,25H,11-14,16H2 PGNHBJGIQAEIHD-UHFFFAOYSA-N 50020174 1-Benzofuran-7-yl-4-[5-(4-fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-piperazine::CHEMBL292187::Elopiprazole D(2) dopamine receptor Rattus norvegicus 0.450000 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 208917 103931091 CHEMBL292187 ZINC53098495 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030175 C(N1CCN(CC1)c1cccc2OCCCOc12)c1ccc([nH]1)-c1ccccc1 InChI=1S/C24H27N3O2/c1-2-6-19(7-3-1)21-11-10-20(25-21)18-26-12-14-27(15-13-26)22-8-4-9-23-24(22)29-17-5-16-28-23/h1-4,6-11,25H,5,12-18H2 FUNCKYBIXPVXIG-UHFFFAOYSA-N 50020177 1-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-6-yl)-4-(5-phenyl-1H-pyrrol-2-ylmethyl)-piperazine::CHEMBL61294 D(2) dopamine receptor Rattus norvegicus 0.680000 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198557 103931094 CHEMBL61294 ZINC29566140 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030176 COc1ccccc1N1CCN(Cc2ccc([nH]2)-c2ccc(cc2)C(C)C)CC1 InChI=1S/C25H31N3O/c1-19(2)20-8-10-21(11-9-20)23-13-12-22(26-23)18-27-14-16-28(17-15-27)24-6-4-5-7-25(24)29-3/h4-13,19,26H,14-18H2,1-3H3 GXFASNXOTFQSAP-UHFFFAOYSA-N 50020179 1-[5-(4-Isopropyl-phenyl)-1H-pyrrol-2-ylmethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL432330 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198547 103931096 CHEMBL432330 ZINC29567592 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030177 COc1ccccc1N1CCN(Cc2ccc([nH]2)-c2ccccc2OC)CC1 InChI=1S/C23H27N3O2/c1-27-22-9-5-3-7-19(22)20-12-11-18(24-20)17-25-13-15-26(16-14-25)21-8-4-6-10-23(21)28-2/h3-12,24H,13-17H2,1-2H3 JKBRWESDCBVYOF-UHFFFAOYSA-N 50020181 1-(2-Methoxy-phenyl)-4-[5-(2-methoxy-phenyl)-1H-pyrrol-2-ylmethyl]-piperazine::CHEMBL60593 D(2) dopamine receptor Rattus norvegicus 6.5 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198549 103931098 CHEMBL60593 ZINC29566159 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030179 COc1ccccc1N1CCN(Cc2ccc([nH]2)-c2ccccc2)CC1 InChI=1S/C22H25N3O/c1-26-22-10-6-5-9-21(22)25-15-13-24(14-16-25)17-19-11-12-20(23-19)18-7-3-2-4-8-18/h2-12,23H,13-17H2,1H3 MRUAJTDSBABAGD-UHFFFAOYSA-N 50020182 1-(2-Methoxy-phenyl)-4-(5-phenyl-1H-pyrrol-2-ylmethyl)-piperazine::CHEMBL61365 D(2) dopamine receptor Rattus norvegicus 0.760000 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198545 103931099 CHEMBL61365 ZINC29563129 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030182 CCCn1c(CN2CCN(CC2)c2ccccc2OC)ccc1-c1ccc(F)cc1 InChI=1S/C25H30FN3O/c1-3-14-29-22(12-13-23(29)20-8-10-21(26)11-9-20)19-27-15-17-28(18-16-27)24-6-4-5-7-25(24)30-2/h4-13H,3,14-19H2,1-2H3 OHWHMRUDEFTPDT-UHFFFAOYSA-N 50020183 1-[5-(4-Fluoro-phenyl)-1-propyl-1H-pyrrol-2-ylmethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL291553 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300912 103931100 CHEMBL291553 ZINC29566173 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030183 Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)c1cccc2ccoc12 InChI=1S/C21H22FN3O2/c22-18-6-4-17(5-7-18)21(26)23-9-10-24-11-13-25(14-12-24)19-3-1-2-16-8-15-27-20(16)19/h1-8,15H,9-14H2,(H,23,26) OETSERFTYLQOCP-UHFFFAOYSA-N 50020178 CHEMBL294633::CHEMBL555633::N-[2-(4-Benzofuran-7-yl-piperazin-1-yl)-ethyl]-4-fluoro-benzamide D(2) dopamine receptor Rattus norvegicus 7.1 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020178&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9999042 103931095 CHEMBL555633CHEMBL294633 ZINC12356235 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030185 COc1ccccc1N1CCN(Cc2ccc(-c3ccc(F)cc3)n2CCO)CC1 InChI=1S/C24H28FN3O2/c1-30-24-5-3-2-4-23(24)27-14-12-26(13-15-27)18-21-10-11-22(28(21)16-17-29)19-6-8-20(25)9-7-19/h2-11,29H,12-18H2,1H3 FYHOYGUHSFBYTB-UHFFFAOYSA-N 50020184 2-{2-(4-Fluoro-phenyl)-5-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-pyrrol-1-yl}-ethanol::CHEMBL59457 D(2) dopamine receptor Rattus norvegicus 52 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020184&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198553 103931101 CHEMBL59457 ZINC29566700 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030186 COc1ccccc1N1CCN(Cc2ccc([nH]2)-c2ccc(F)cc2)CC1 InChI=1S/C22H24FN3O/c1-27-22-5-3-2-4-21(22)26-14-12-25(13-15-26)16-19-10-11-20(24-19)17-6-8-18(23)9-7-17/h2-11,24H,12-16H2,1H3 VHRUYTMJYBYBCS-UHFFFAOYSA-N 50019961 1-[5-(4-Fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL418140 D(2) dopamine receptor Rattus norvegicus 0.960000 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900359 103930884 CHEMBL418140 ZINC29566169 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030187 COc1ccccc1C1CCN(Cc2ccc([nH]2)-c2ccccc2)CC1 InChI=1S/C23H26N2O/c1-26-23-10-6-5-9-21(23)18-13-15-25(16-14-18)17-20-11-12-22(24-20)19-7-3-2-4-8-19/h2-12,18,24H,13-17H2,1H3 CHUWNLPOBRVCIL-UHFFFAOYSA-N 50020185 4-(2-Methoxy-phenyl)-1-(5-phenyl-1H-pyrrol-2-ylmethyl)-piperidine::CHEMBL57945 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020185&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198560 103931102 CHEMBL57945 ZINC29563744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030189 Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1cccc2ccoc12 InChI=1S/C22H23FN2O2/c23-19-8-6-17(7-9-19)21(26)5-2-11-24-12-14-25(15-13-24)20-4-1-3-18-10-16-27-22(18)20/h1,3-4,6-10,16H,2,5,11-15H2 HUACSDTUNPSEBC-UHFFFAOYSA-N 50020180 4-(4-Benzofuran-7-yl-piperazin-1-yl)-1-(4-fluoro-phenyl)-butan-1-one::CHEMBL541077::CHEMBL58613 D(2) dopamine receptor Rattus norvegicus 5.1 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020180&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10316830 103931097 CHEMBL58613CHEMBL541077 ZINC13738312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030191 Fc1ccc(cc1)-c1ccc(CN2CCC(CC2)c2ccccc2)[nH]1 InChI=1S/C22H23FN2/c23-20-8-6-19(7-9-20)22-11-10-21(24-22)16-25-14-12-18(13-15-25)17-4-2-1-3-5-17/h1-11,18,24H,12-16H2 GPEDENYUQYAAIH-UHFFFAOYSA-N 50020186 1-[5-(4-Fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-4-phenyl-piperidine::CHEMBL292642 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020186&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198561 103931103 CHEMBL292642 ZINC29567532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030192 OC1(CCN(Cc2ccc([nH]2)-c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C22H22ClFN2O/c23-18-5-3-17(4-6-18)22(27)11-13-26(14-12-22)15-20-9-10-21(25-20)16-1-7-19(24)8-2-16/h1-10,25,27H,11-15H2 KBCLXZNRFSYDIG-UHFFFAOYSA-N 50019958 4-(4-Chloro-phenyl)-1-[5-(4-fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-piperidin-4-ol::CHEMBL59186 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900355 103930881 CHEMBL59186 ZINC29568698 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030193 Fc1ccc(cc1)-c1ccc(CN2CCN(CC2)c2cccc(c2)C(F)(F)F)[nH]1 InChI=1S/C22H21F4N3/c23-18-6-4-16(5-7-18)21-9-8-19(27-21)15-28-10-12-29(13-11-28)20-3-1-2-17(14-20)22(24,25)26/h1-9,14,27H,10-13,15H2 QLTKTGNZPRTRJR-UHFFFAOYSA-N 50020188 1-[5-(4-Fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL411722 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020188&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198555 103931105 CHEMBL411722 ZINC29560023 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030194 COc1ccccc1N1CCN(Cc2ccc([nH]2)-c2ccc(cc2)C(F)(F)F)CC1 InChI=1S/C23H24F3N3O/c1-30-22-5-3-2-4-21(22)29-14-12-28(13-15-29)16-19-10-11-20(27-19)17-6-8-18(9-7-17)23(24,25)26/h2-11,27H,12-16H2,1H3 WUVWCDVPHNGEEU-UHFFFAOYSA-N 50020187 1-(2-Methoxy-phenyl)-4-[5-(4-trifluoromethyl-phenyl)-1H-pyrrol-2-ylmethyl]-piperazine::CHEMBL58962 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020187&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198546 103931104 CHEMBL58962 ZINC29568958 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030195 COc1ccccc1N1CCN(Cc2ccc(-c3ccc(F)cc3)n2C)CC1 InChI=1S/C23H26FN3O/c1-25-20(11-12-21(25)18-7-9-19(24)10-8-18)17-26-13-15-27(16-14-26)22-5-3-4-6-23(22)28-2/h3-12H,13-17H2,1-2H3 SBUKRQHOQWLSOZ-UHFFFAOYSA-N 50020189 1-[5-(4-Fluoro-phenyl)-1-methyl-1H-pyrrol-2-ylmethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL57985 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020189&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198551 103931106 CHEMBL57985 ZINC29566986 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030196 Fc1ccc(cc1)C(=O)N1CCN(Cc2ccc([nH]2)-c2ccc(F)cc2)CC1 InChI=1S/C22H21F2N3O/c23-18-5-1-16(2-6-18)21-10-9-20(25-21)15-26-11-13-27(14-12-26)22(28)17-3-7-19(24)8-4-17/h1-10,25H,11-15H2 ZKSNUHKBDLQEIL-UHFFFAOYSA-N 50020190 (4-Fluoro-phenyl)-{4-[5-(4-fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-piperazin-1-yl}-methanone::CHEMBL58099 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020190&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198567 103931107 CHEMBL58099 ZINC29564206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030197 COc1ccccc1N1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C21H25FN2O2/c1-26-21-7-3-2-5-19(21)24-15-13-23(14-16-24)12-4-6-20(25)17-8-10-18(22)11-9-17/h2-3,5,7-11H,4,6,12-16H2,1H3 IRYFCWPNDIUQOW-UHFFFAOYSA-N 50019959 1-(4-Fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one::1-(4-Fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one(fluanisone)::CHEMBL58792::Fluanisone D(2) dopamine receptor Rattus norvegicus 2.4 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15139 103930882 CHEMBL58792 ZINC04213325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030198 COc1ccccc1N1CCN(CCNC(=O)c2ccc(F)cc2)CC1 InChI=1S/C20H24FN3O2/c1-26-19-5-3-2-4-18(19)24-14-12-23(13-15-24)11-10-22-20(25)16-6-8-17(21)9-7-16/h2-9H,10-15H2,1H3,(H,22,25) GTATVXRFYOQYFS-UHFFFAOYSA-N 50019960 4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL58377 D(2) dopamine receptor Rattus norvegicus 4.3 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13318472 103930883 CHEMBL58377 ZINC52969696 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031344 CCN1CCC[C@H]1CNC(=O)c1cc(I)ccc1OC InChI=1S/C15H21IN2O2/c1-3-18-8-4-5-12(18)10-17-15(19)13-9-11(16)6-7-14(13)20-2/h6-7,9,12H,3-5,8,10H2,1-2H3,(H,17,19)/t12-/m0/s1 JHMTYLJMPBFCTD-LBPRGKRZSA-N 50012967 CHEMBL49897::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide (iodopride)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide(iodopride) D(2) dopamine receptor Rattus norvegicus 1.5 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977544 103925215 CHEMBL49897 ZINC06385022 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031346 CCN1CCC[C@@H]1CNC(=O)c1cc(I)ccc1OC InChI=1S/C15H21IN2O2/c1-3-18-8-4-5-12(18)10-17-15(19)13-9-11(16)6-7-14(13)20-2/h6-7,9,12H,3-5,8,10H2,1-2H3,(H,17,19)/t12-/m1/s1 JHMTYLJMPBFCTD-GFCCVEGCSA-N 50452484 CHEMBL2115023 D(2) dopamine receptor Rattus norvegicus 145 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452484&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3082754 225145692 CHEMBL2115023 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031349 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 1900 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031350 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 1860 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031351 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030199 COc1ccccc1N1CCN(Cc2ccc([nH]2)-c2cccc(Cl)c2)CC1 InChI=1S/C22H24ClN3O/c1-27-22-8-3-2-7-21(22)26-13-11-25(12-14-26)16-19-9-10-20(24-19)17-5-4-6-18(23)15-17/h2-10,15,24H,11-14,16H2,1H3 MMOBVFCLEWJYLP-UHFFFAOYSA-N 50020191 1-[5-(3-Chloro-phenyl)-1H-pyrrol-2-ylmethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL301035 D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1021/jm00118a011 10.7270/Q2SJ1JMB 2902226 van Wijngaarden, I; Kruse, CG; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020191&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198548 103931108 CHEMBL301035 ZINC29566952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030208 O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26) JVGBTTIJPBFLTE-UHFFFAOYSA-N 50020192 8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine D(2) dopamine receptor Rattus norvegicus 1.45 ChEMBL 10.1021/jm00118a017 10.7270/Q2NV9H7W 2902227 Nikam, SS; Martin, AR; Nelson, DL University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5268 103931109 CHEMBL300555 53 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031461 OCCN1CCN(CC1)[C@@H]1C[C@H](c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2/t19-,21+/m0/s1 JSBWGXQXCRYYTG-PZJWPPBQSA-N 50019966 2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL95636::Tefludazine D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71240 103930889 CHEMBL95636 ZINC22463345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031462 Fc1ccc(cc1)[C@@H]1C[C@@H](N2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H29FN4O/c25-19-7-5-18(6-8-19)22-17-23(21-4-2-1-3-20(21)22)28-14-11-27(12-15-28)13-16-29-10-9-26-24(29)30/h1-8,22-23H,9-17H2,(H,26,30)/t22-,23+/m0/s1 GHAMYXPEZSUOCU-XZOQPEGZSA-N 50020232 1-(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one(Irindalone)::CHEMBL73461::Irindalone D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020232&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65845 103931146 CHEMBL73461 ZINC22463226 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029308 Fc1ccc2[nH]c3CN(CCc4ccc5ccccc5n4)CCc3c2c1 InChI=1S/C22H20FN3/c23-16-6-8-21-19(13-16)18-10-12-26(14-22(18)25-21)11-9-17-7-5-15-3-1-2-4-20(15)24-17/h1-8,13,25H,9-12,14H2 HCVJCBSIUZWNIM-UHFFFAOYSA-N 50019732 6-Fluoro-2-(2-quinolin-2-yl-ethyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12662 D(2) dopamine receptor Rattus norvegicus 216 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019732&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15599293 103930655 CHEMBL12662 ZINC34602041 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029309 Fc1ccc(cc1)C(CCCN1CCc2c(C1)[nH]c1ccccc21)c1ccc(F)cc1 InChI=1S/C27H26F2N2/c28-21-11-7-19(8-12-21)23(20-9-13-22(29)14-10-20)5-3-16-31-17-15-25-24-4-1-2-6-26(24)30-27(25)18-31/h1-2,4,6-14,23,30H,3,5,15-18H2 LCERGTRVKSJRQA-UHFFFAOYSA-N 50019734 2-[4,4-Bis-(4-fluoro-phenyl)-butyl]-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12416 D(2) dopamine receptor Rattus norvegicus 145 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268084 103930657 CHEMBL12416 ZINC36093021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029310 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029311 Fc1ccc2[nH]c3CN(CCCCc4ccnc5ccccc45)CCc3c2c1 InChI=1S/C24H24FN3/c25-18-8-9-23-21(15-18)20-11-14-28(16-24(20)27-23)13-4-3-5-17-10-12-26-22-7-2-1-6-19(17)22/h1-2,6-10,12,15,27H,3-5,11,13-14,16H2 AEBCLIZNJBUUSQ-UHFFFAOYSA-N 50019733 6-Fluoro-2-(4-quinolin-4-yl-butyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL13120 D(2) dopamine receptor Rattus norvegicus 194 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019733&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268143 103930656 CHEMBL13120 ZINC36093032 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029312 FC(F)(F)c1cccc(c1)N1CCN(CCCN2CCc3c(C2)[nH]c2ccccc32)CC1 InChI=1S/C25H29F3N4/c26-25(27,28)19-5-3-6-20(17-19)32-15-13-30(14-16-32)10-4-11-31-12-9-22-21-7-1-2-8-23(21)29-24(22)18-31/h1-3,5-8,17,29H,4,9-16,18H2 AGWOUMXKBMIRJT-UHFFFAOYSA-N 50019735 2-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-propyl}-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12726 D(2) dopamine receptor Rattus norvegicus 407 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268163 103930658 CHEMBL12726 ZINC36093026 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029313 Clc1cccc(c1)N1CCN(CCCn2c3CN(CCc4ccccn4)CCc3c3ccccc23)CC1 InChI=1S/C31H36ClN5/c32-25-7-5-9-27(23-25)36-21-19-34(20-22-36)15-6-16-37-30-11-2-1-10-28(30)29-13-18-35(24-31(29)37)17-12-26-8-3-4-14-33-26/h1-5,7-11,14,23H,6,12-13,15-22,24H2 LHEHOKKOUQZWGF-UHFFFAOYSA-N 50019737 9-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-2-(2-pyridin-2-yl-ethyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12429 D(2) dopamine receptor Rattus norvegicus 213 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268158 103930660 CHEMBL12429 ZINC36093031 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029314 Clc1ccc2[nH]c3CN(CCc4ccncc4)CCc3c2c1 InChI=1S/C18H18ClN3/c19-14-1-2-17-16(11-14)15-6-10-22(12-18(15)21-17)9-5-13-3-7-20-8-4-13/h1-4,7-8,11,21H,5-6,9-10,12H2 IECKPENINRJPEF-UHFFFAOYSA-N 50019736 6-Chloro-2-(2-pyridin-4-yl-ethyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL273618 D(2) dopamine receptor Rattus norvegicus 768 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019736&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268205 103930659 CHEMBL273618 ZINC36093025 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029316 Fc1ccc2[nH]c3CN(CCCCc4ccncc4)CCc3c2c1 InChI=1S/C20H22FN3/c21-16-4-5-19-18(13-16)17-8-12-24(14-20(17)23-19)11-2-1-3-15-6-9-22-10-7-15/h4-7,9-10,13,23H,1-3,8,11-12,14H2 OHEFAVHDCYKXAO-UHFFFAOYSA-N 50019739 6-Fluoro-2-(4-pyridin-4-yl-butyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL267773 D(2) dopamine receptor Rattus norvegicus 720 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019739&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268199 103930662 CHEMBL267773 ZINC36093024 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029317 Fc1ccc(cc1)C(=O)CCCn1c2CN(CCc3ccccn3)CCc2c2ccccc12 InChI=1S/C28H28FN3O/c29-22-12-10-21(11-13-22)28(33)9-5-17-32-26-8-2-1-7-24(26)25-15-19-31(20-27(25)32)18-14-23-6-3-4-16-30-23/h1-4,6-8,10-13,16H,5,9,14-15,17-20H2 HXVCXSCIXOEWNA-UHFFFAOYSA-N 50019740 1-(4-Fluoro-phenyl)-4-[2-(2-pyridin-2-yl-ethyl)-1,2,3,4-tetrahydro-beta-carbolin-9-yl]-butan-1-one::CHEMBL416708 D(2) dopamine receptor Rattus norvegicus 118 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019740&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268248 103930663 CHEMBL416708 ZINC36093020 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029318 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029319 C[C@H]1CN(CCCn2c3ccccc3c3ccccc23)C[C@@H](C)N1 InChI=1S/C21H27N3/c1-16-14-23(15-17(2)22-16)12-7-13-24-20-10-5-3-8-18(20)19-9-4-6-11-21(19)24/h3-6,8-11,16-17,22H,7,12-15H2,1-2H3/t16-,17+ GUDVQJXODNJRIJ-CALCHBBNSA-N 50019742 9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9H-carbazole::9-(3-(3,5-dimethylpiperazin-1-yl)propyl)-9H-carbazole::9-[3-((3R,5R)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-((3R,5S)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-((3S,5R)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole (Rimcazole) (BW234U)::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole(rimcazole)::CHEMBL275707::RIMCAZOLE D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019742&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53389 103930665 CHEMBL275707 ZINC22920326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029320 C(CCc1ccnc2ccccc12)CN1CCc2c(C1)[nH]c1ccccc21 InChI=1S/C24H25N3/c1-3-10-22-19(8-1)18(12-14-25-22)7-5-6-15-27-16-13-21-20-9-2-4-11-23(20)26-24(21)17-27/h1-4,8-12,14,26H,5-7,13,15-17H2 ZVHBEVLGJGQNKG-UHFFFAOYSA-N 50019741 2-(4-Quinolin-4-yl-butyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12312 D(2) dopamine receptor Rattus norvegicus 172 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019741&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15599288 103930664 CHEMBL12312 ZINC34602036 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029321 C(Cc1ccccn1)N1CCc2c(C1)n(Cc1ccccc1)c1ccccc21 InChI=1S/C25H25N3/c1-2-8-20(9-3-1)18-28-24-12-5-4-11-22(24)23-14-17-27(19-25(23)28)16-13-21-10-6-7-15-26-21/h1-12,15H,13-14,16-19H2 QHDUKKOEVFYFNN-UHFFFAOYSA-N 50019743 9-Benzyl-2-(2-pyridin-2-yl-ethyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL267775 D(2) dopamine receptor Rattus norvegicus 185 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019743&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20134447 103930666 CHEMBL267775 ZINC36093027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029322 C(CCCN1CCc2c(C1)[nH]c1ccccc21)CCCc1ccncc1 InChI=1S/C23H29N3/c1(2-4-8-19-11-14-24-15-12-19)3-7-16-26-17-13-21-20-9-5-6-10-22(20)25-23(21)18-26/h5-6,9-12,14-15,25H,1-4,7-8,13,16-18H2 FOMPIZYPMSVLBB-UHFFFAOYSA-N 50019744 2-(7-Pyridin-4-yl-heptyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12347 D(2) dopamine receptor Rattus norvegicus 252 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019744&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15599285 103930667 CHEMBL12347 ZINC34602033 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029323 C(CN1CCN(CC1)c1ncccn1)CN1CCc2c(C1)[nH]c1ccccc21 InChI=1S/C22H28N6/c1-2-6-20-18(5-1)19-7-12-27(17-21(19)25-20)11-4-10-26-13-15-28(16-14-26)22-23-8-3-9-24-22/h1-3,5-6,8-9,25H,4,7,10-17H2 ATPAOWGTPARMOQ-UHFFFAOYSA-N 50019745 2-[3-(4-Pyrimidin-2-yl-piperazin-1-yl)-propyl]-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL275278 D(2) dopamine receptor Rattus norvegicus 574 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019745&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13852816 103930668 CHEMBL275278 ZINC34169719 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029324 Clc1cccc(c1)N1CCN(CCCn2c3CN(CCCc4cccnc4)CCc3c3ccccc23)CC1 InChI=1S/C32H38ClN5/c33-27-9-3-10-28(23-27)37-21-19-35(20-22-37)16-6-17-38-31-12-2-1-11-29(31)30-13-18-36(25-32(30)38)15-5-8-26-7-4-14-34-24-26/h1-4,7,9-12,14,23-24H,5-6,8,13,15-22,25H2 MYITWYAKEJQAFS-UHFFFAOYSA-N 50019746 9-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-2-(3-pyridin-3-yl-propyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12564 D(2) dopamine receptor Rattus norvegicus 306 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019746&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268210 103930669 CHEMBL12564 ZINC36093023 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029325 Fc1ccc(cc1)C(N1CCN(CCCN2CCc3c(C2)[nH]c2ccccc32)CC1)c1ccc(F)cc1 InChI=1S/C31H34F2N4/c32-25-10-6-23(7-11-25)31(24-8-12-26(33)13-9-24)37-20-18-35(19-21-37)15-3-16-36-17-14-28-27-4-1-2-5-29(27)34-30(28)22-36/h1-2,4-13,31,34H,3,14-22H2 LDFFNESLZJXVMY-UHFFFAOYSA-N 50019747 2-(3-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl}-propyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12460 D(2) dopamine receptor Rattus norvegicus 143 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019747&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13852817 103930670 CHEMBL12460 ZINC22441693 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029326 OC1(CCN(CCCn2c3CN(CCc4ccccn4)CCc3c3ccccc23)CC1)c1ccc(Cl)cc1 InChI=1S/C32H37ClN4O/c33-26-11-9-25(10-12-26)32(38)15-22-35(23-16-32)18-5-19-37-30-8-2-1-7-28(30)29-14-21-36(24-31(29)37)20-13-27-6-3-4-17-34-27/h1-4,6-12,17,38H,5,13-16,18-24H2 QUSHWYMMZWAFBH-UHFFFAOYSA-N 50019748 4-(4-Chloro-phenyl)-1-{3-[2-(2-pyridin-2-yl-ethyl)-1,2,3,4-tetrahydro-beta-carbolin-9-yl]-propyl}-piperidin-4-ol::CHEMBL12491 D(2) dopamine receptor Rattus norvegicus 91 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019748&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20134451 103930671 CHEMBL12491 ZINC36093022 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029328 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029330 C(CCc1ccc2ccccc2n1)CN1CCc2c(C1)[nH]c1ccccc21 InChI=1S/C24H25N3/c1-3-10-22-18(7-1)12-13-19(25-22)8-5-6-15-27-16-14-21-20-9-2-4-11-23(20)26-24(21)17-27/h1-4,7,9-13,26H,5-6,8,14-17H2 WKXZOEAHOWJCTL-UHFFFAOYSA-N 50019738 2-(4-Quinolin-2-yl-butyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12533 D(2) dopamine receptor Rattus norvegicus 83 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019738&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15599290 103930661 CHEMBL12533 ZINC34602038 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029331 C(Cc1ccc2ccccc2n1)N1CCc2c(C1)[nH]c1ccccc21 InChI=1S/C22H21N3/c1-3-7-20-16(5-1)9-10-17(23-20)11-13-25-14-12-19-18-6-2-4-8-21(18)24-22(19)15-25/h1-10,24H,11-15H2 CJBOQCANXATUMA-UHFFFAOYSA-N 50019750 2-(2-Quinolin-2-yl-ethyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL274781 D(2) dopamine receptor Rattus norvegicus 116 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019750&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15599287 103930673 CHEMBL274781 ZINC34602035 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029332 FC(F)(F)c1ccc(CN2CCN(CCCN3CCc4c(C3)[nH]c3ccccc43)CC2)cc1 InChI=1S/C26H31F3N4/c27-26(28,29)21-8-6-20(7-9-21)18-33-16-14-31(15-17-33)11-3-12-32-13-10-23-22-4-1-2-5-24(22)30-25(23)19-32/h1-2,4-9,30H,3,10-19H2 NXFMXOKIVYLELN-UHFFFAOYSA-N 50019752 2-{3-[4-(4-Trifluoromethyl-benzyl)-piperazin-1-yl]-propyl}-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12755 D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019752&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44268178 103930675 CHEMBL12755 ZINC36093030 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029333 C(CN1CCc2c(C1)[nH]c1ccccc21)Cc1cccnc1 InChI=1S/C19H21N3/c1-2-8-18-16(7-1)17-9-12-22(14-19(17)21-18)11-4-6-15-5-3-10-20-13-15/h1-3,5,7-8,10,13,21H,4,6,9,11-12,14H2 OPKWRJFGFHYVMY-UHFFFAOYSA-N 50019751 2-(3-Pyridin-3-yl-propyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL274410 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019751&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20155411 103930674 CHEMBL274410 ZINC36093029 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029334 C(CN1CCc2c(C1)[nH]c1ccccc21)Cc1ccncc1 InChI=1S/C19H21N3/c1-2-6-18-16(5-1)17-9-13-22(14-19(17)21-18)12-3-4-15-7-10-20-11-8-15/h1-2,5-8,10-11,21H,3-4,9,12-14H2 LGZZWINDXDHJPI-UHFFFAOYSA-N 50019753 2-(3-Pyridin-4-yl-propyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL440456 D(2) dopamine receptor Rattus norvegicus 1120 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019753&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20155409 103930676 CHEMBL440456 ZINC36093028 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029335 C(CCc1ccncc1)CN1CCc2c(C1)[nH]c1ccccc21 InChI=1S/C20H23N3/c1-2-7-19-17(6-1)18-10-14-23(15-20(18)22-19)13-4-3-5-16-8-11-21-12-9-16/h1-2,6-9,11-12,22H,3-5,10,13-15H2 RZPOTXDVVTUINK-UHFFFAOYSA-N 50019749 2-(4-Pyridin-4-yl-butyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL274446 D(2) dopamine receptor Rattus norvegicus 525 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019749&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15599286 103930672 CHEMBL274446 ZINC34602034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030389 CC1(CC(=O)N(CCCCN2CCN(CC2)c2ncccn2)C1=O)c1ccccc1 InChI=1S/C23H29N5O2.C7H8O3S/c1-23(19-8-3-2-4-9-19)18-20(29)28(21(23)30)13-6-5-12-26-14-16-27(17-15-26)22-24-10-7-11-25-22;1-6-2-4-7(5-3-6)11(8,9)10/h2-4,7-11H,5-6,12-18H2,1H3;2-5H,1H3,(H,8,9,10) FSCBLMAAPDAHSC-UHFFFAOYSA-N 50452297 CHEMBL2114399 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452297&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71458100 225145643 CHEMBL2114399 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030390 CC1(CC(=O)N(CCCCN2CCN(CC2)c2ncccn2)C1=O)c1ccccc1 InChI=1S/C23H29N5O2.ClH/c1-23(19-8-3-2-4-9-19)18-20(29)28(21(23)30)13-6-5-12-26-14-16-27(17-15-26)22-24-10-7-11-25-22;/h2-4,7-11H,5-6,12-18H2,1H3;1H YDZYHWAFOJBMIM-UHFFFAOYSA-N 50452296 CHEMBL2115344 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452296&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71458132 225145642 CHEMBL2115344 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50617683 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.2 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030619 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030622 Oc1cccc2[C@@H]3CCCN[C@H]3CCc12 InChI=1S/C13H17NO/c15-13-5-1-3-9-10-4-2-8-14-12(10)7-6-11(9)13/h1,3,5,10,12,14-15H,2,4,6-8H2/t10?,12-/m0/s1 RWDHALOKAOEZPC-KFJBMODSSA-N 50047143 1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol::BDBM50452346::CHEMBL56519 D(2) dopamine receptor Rattus norvegicus 92 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047143&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9882257 103977831 CHEMBL24357CHEMBL56519 ZINC12355899 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030631 CCCN1CCC[C@@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m0/s1 ANYSYRVXKLTFPB-DZGCQCFKSA-N 50452347 CHEMBL306162 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039960 225145660 CHEMBL306162 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030632 CCCN1CCCC2C1CCc1ccc(O)cc21 InChI=1S/C16H23NO/c1-2-9-17-10-3-4-14-15-11-13(18)7-5-12(15)6-8-16(14)17/h5,7,11,14,16,18H,2-4,6,8-10H2,1H3 LGRLJXCJYMYBLM-UHFFFAOYSA-N 50018643 (R,R)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol::(S,S)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol::4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol::CHEMBL67583::rac-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 25.0 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039976 103929735 CHEMBL67583 ZINC26275274 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030634 Oc1cccc2[C@H]3CCCN[C@@H]3CCc12 InChI=1S/C13H17NO/c15-13-5-1-3-9-10-4-2-8-14-12(10)7-6-11(9)13/h1,3,5,10,12,14-15H,2,4,6-8H2/t10-,12-/m1/s1 RWDHALOKAOEZPC-ZYHUDNBSSA-N 50452344 CHEMBL2114055 D(2) dopamine receptor Rattus norvegicus 1550 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 125678 225145657 CHEMBL2114055 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030637 Oc1cccc(c1)[C@@H]1CCCNC1 InChI=1S/C11H15NO/c13-11-5-1-3-9(7-11)10-4-2-6-12-8-10/h1,3,5,7,10,12-13H,2,4,6,8H2/t10-/m1/s1 HYUOAVGLJXTEGX-SNVBAGLBSA-N 50452348 CHEMBL8033 D(2) dopamine receptor Rattus norvegicus 1750 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937954 225145661 CHEMBL8033 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030638 CCCN1CCC[C@H]2[C@@H]1CCc1c(O)cccc21 InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m1/s1 ANYSYRVXKLTFPB-HIFRSBDPSA-N 50452345 CHEMBL2114053 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039962 225145658 CHEMBL2114053 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030639 CCCCN1CCCC2C1CCc1ccc(O)cc21 InChI=1S/C17H25NO/c1-2-3-10-18-11-4-5-15-16-12-14(19)8-6-13(16)7-9-17(15)18/h6,8,12,15,17,19H,2-5,7,9-11H2,1H3 ZIUSEXYMNHXTCK-UHFFFAOYSA-N 50018644 CHEMBL68432::rac-4-Butyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 10400 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039982 103929736 CHEMBL68432 ZINC26275263 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030640 CCCN1CCC[C@@H]2[C@@H]1CCc1c(O)cccc21 InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15-/m0/s1 ANYSYRVXKLTFPB-ZFWWWQNUSA-N 50273466 (+/-)-trans-4-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-7-ol::4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol::CHEMBL450863 D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039958 104117587 CHEMBL450863 ZINC05833784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029667 C[S+](C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClNS2/c1-21(2)11-5-10-19-14-6-3-4-7-16(14)20-17-9-8-13(18)12-15(17)19/h3-4,6-9,12H,5,10-11H2,1-2H3/q+1 FWKTXSPMNPROHO-UHFFFAOYSA-N 50019878 CHEMBL44394::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-sulfonium; iodide D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00392a019 10.7270/Q2FB51ZZ 2887659 Harrold, MW; Chang, YA; Wallace, RA; Farooqui, T; Wallace, LJ; Uretsky, N; Miller, DD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019878&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44289163 103930801 CHEMBL44394 ZINC29389247 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029668 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm00392a019 10.7270/Q2FB51ZZ 2887659 Harrold, MW; Chang, YA; Wallace, RA; Farooqui, T; Wallace, LJ; Uretsky, N; Miller, DD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029669 C[N+](C)(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H22ClN2S/c1-21(2,3)12-6-11-20-15-7-4-5-8-17(15)22-18-10-9-14(19)13-16(18)20/h4-5,7-10,13H,6,11-12H2,1-3H3/q+1 RGKWYLVIZNCRIY-UHFFFAOYSA-N 50019879 CHEMBL279905::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-trimethyl-ammonium; iodide D(2) dopamine receptor Rattus norvegicus 2150 ChEMBL 10.1021/jm00392a019 10.7270/Q2FB51ZZ 2887659 Harrold, MW; Chang, YA; Wallace, RA; Farooqui, T; Wallace, LJ; Uretsky, N; Miller, DD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019879&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9683 103930802 CHEMBL279905 ZINC01677751 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029722 CCn1[nH]c(C)c(C(=N)c2cccc(Cl)c2)c1=O InChI=1S/C13H14ClN3O/c1-3-17-13(18)11(8(2)16-17)12(15)9-5-4-6-10(14)7-9/h4-7,15-16H,3H2,1-2H3 UUXXSEMFXKVEAB-UHFFFAOYSA-N 50019908 4-[(3-Chloro-phenyl)-imino-methyl]-2-ethyl-5-methyl-2H-pyrazol-3-ol::CHEMBL3144764 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019908&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044084 103930831 CHEMBL3144764CHEMBL301339 ZINC29483850 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029723 CC(=O)\N=C(\c1c(C)[nH]n(C)c1=O)c1cccc(Cl)c1 InChI=1S/C14H14ClN3O2/c1-8-12(14(20)18(3)17-8)13(16-9(2)19)10-5-4-6-11(15)7-10/h4-7,17H,1-3H3 IQRITSAKDYQQCU-UHFFFAOYSA-N 50019909 CHEMBL3144632::N-[(3-Chloro-phenyl)-(5-hydroxy-1,3-dimethyl-1H-pyrazol-4-yl)-methylene]-acetamide D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019909&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044085 103930832 CHEMBL3144632CHEMBL51212 ZINC29481032 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029724 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 2.8 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029725 Cc1[nH]n(C)c(=O)c1C(=N)c1ccccc1 InChI=1S/C12H13N3O/c1-8-10(12(16)15(2)14-8)11(13)9-6-4-3-5-7-9/h3-7,13-14H,1-2H3 NVHVNTYRUUWBGD-UHFFFAOYSA-N 50019910 4-(Imino-phenyl-methyl)-2,5-dimethyl-2H-pyrazol-3-ol::CHEMBL3144759 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019910&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044086 103930833 CHEMBL3144759CHEMBL300639 ZINC29480142 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029726 CCn1[nH]c(C)c(C(=N)c2ccccc2)c1=O InChI=1S/C13H15N3O/c1-3-16-13(17)11(9(2)15-16)12(14)10-7-5-4-6-8-10/h4-8,14-15H,3H2,1-2H3 KPNLZQWEHKUZFE-UHFFFAOYSA-N 50019911 2-Ethyl-4-(imino-phenyl-methyl)-5-methyl-2H-pyrazol-3-ol::CHEMBL3144620 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019911&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044087 103930834 CHEMBL3144620CHEMBL50105 ZINC29479408 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029727 Cc1[nH]n(C)c(=O)c1C(=N)c1ccc(F)cc1 InChI=1S/C12H12FN3O/c1-7-10(12(17)16(2)15-7)11(14)8-3-5-9(13)6-4-8/h3-6,14-15H,1-2H3 XYGRRLYVLKIKIY-UHFFFAOYSA-N 50019912 4-[(4-Fluoro-phenyl)-imino-methyl]-2,5-dimethyl-2H-pyrazol-3-ol::CHEMBL3144805 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019912&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044088 103930835 CHEMBL3144805CHEMBL432311 ZINC29480146 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029729 Cc1[nH]n(C)c(=O)c1C(=N)c1cccc(Br)c1 InChI=1S/C12H12BrN3O/c1-7-10(12(17)16(2)15-7)11(14)8-4-3-5-9(13)6-8/h3-6,14-15H,1-2H3 RGFNDQQWOWFIEC-UHFFFAOYSA-N 50019914 4-[(3-Bromo-phenyl)-imino-methyl]-2,5-dimethyl-2H-pyrazol-3-ol::CHEMBL3144748 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019914&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044090 103930837 CHEMBL3144748CHEMBL299610 ZINC29487665 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029730 CC(C)n1[nH]c(C)c(C(=N)c2cccc(Cl)c2)c1=O InChI=1S/C14H16ClN3O/c1-8(2)18-14(19)12(9(3)17-18)13(16)10-5-4-6-11(15)7-10/h4-8,16-17H,1-3H3 WBZDQZRPVGANAG-UHFFFAOYSA-N 50019915 4-[(3-Chloro-phenyl)-imino-methyl]-2-isopropyl-5-methyl-2H-pyrazol-3-ol::CHEMBL3144634 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019915&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044091 103930838 CHEMBL3144634CHEMBL52516 ZINC29489080 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029731 Cc1[nH]n(C)c(=O)c1C(=N)c1cccc(Cl)c1 InChI=1S/C12H12ClN3O/c1-7-10(12(17)16(2)15-7)11(14)8-4-3-5-9(13)6-8/h3-6,14-15H,1-2H3 GQGIZIKPIPCGCO-UHFFFAOYSA-N 50019913 4-[(3-Chloro-phenyl)-imino-methyl]-2,5-dimethyl-2H-pyrazol-3-ol::CHEMBL3144745 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019913&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044089 103930836 CHEMBL3144745CHEMBL297709 ZINC29481319 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029733 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029734 CCCn1[nH]c(C)c(C(=N)c2cccc(Cl)c2)c1=O InChI=1S/C14H16ClN3O/c1-3-7-18-14(19)12(9(2)17-18)13(16)10-5-4-6-11(15)8-10/h4-6,8,16-17H,3,7H2,1-2H3 QVFFDHPJAWMQJW-UHFFFAOYSA-N 50019918 4-[(3-Chloro-phenyl)-imino-methyl]-5-methyl-2-propyl-2H-pyrazol-3-ol::CHEMBL3144637 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044094 103930841 CHEMBL3144637CHEMBL53937 ZINC29483844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029735 Cc1[nH]n(C)c(=O)c1C(=N)c1ccc(cc1)C(F)(F)F InChI=1S/C13H12F3N3O/c1-7-10(12(20)19(2)18-7)11(17)8-3-5-9(6-4-8)13(14,15)16/h3-6,17-18H,1-2H3 DIEYTRHFEACLSQ-UHFFFAOYSA-N 50019917 4-[Imino-(4-trifluoromethyl-phenyl)-methyl]-2,5-dimethyl-2H-pyrazol-3-ol::CHEMBL3144756 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044093 103930840 CHEMBL3144756CHEMBL300064 ZINC29479865 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029736 Cc1[nH]n(C)c(=O)c1\C(=N\C(=O)C(Cl)Cl)c1cccc(Cl)c1 InChI=1S/C14H12Cl3N3O2/c1-7-10(14(22)20(2)19-7)11(18-13(21)12(16)17)8-4-3-5-9(15)6-8/h3-6,12,19H,1-2H3 SDBCYPPQUUWMKW-UHFFFAOYSA-N 50019916 2,2-Dichloro-N-[(3-chloro-phenyl)-(5-hydroxy-1,3-dimethyl-1H-pyrazol-4-yl)-methylene]-acetamide::CHEMBL3144642 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019916&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044092 103930839 CHEMBL3144642CHEMBL54184 ZINC29482680 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029737 Cc1[nH]n(C)c(=O)c1C(=N)c1cccc(F)c1 InChI=1S/C12H12FN3O/c1-7-10(12(17)16(2)15-7)11(14)8-4-3-5-9(13)6-8/h3-6,14-15H,1-2H3 YBFYHKCKVQQBHD-UHFFFAOYSA-N 50019920 4-[(3-Fluoro-phenyl)-imino-methyl]-2,5-dimethyl-2H-pyrazol-3-ol::CHEMBL3144629 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019920&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044096 103930843 CHEMBL3144629CHEMBL53394 ZINC29484616 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029738 Cc1[nH]n(C)c(=O)c1\C(=N\C(=O)C(F)(F)F)c1cccc(Cl)c1 InChI=1S/C14H11ClF3N3O2/c1-7-10(12(22)21(2)20-7)11(19-13(23)14(16,17)18)8-4-3-5-9(15)6-8/h3-6,20H,1-2H3 QTCDJYBABCSOEQ-UHFFFAOYSA-N 50019919 CHEMBL3144848::N-[(3-Chloro-phenyl)-(5-hydroxy-1,3-dimethyl-1H-pyrazol-4-yl)-methylene]-2,2,2-trifluoro-acetamide D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a021 10.7270/Q29K497N 2888897 Wise, LD; Butler, DE; DeWald, HA; Lustgarten, DM; Pattison, IC; Schweiss, DN; Coughenour, LL; Downs, DA; Heffner, TG; Pugsley, TA Warner-Lambert/Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019919&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 136044095 103930842 CHEMBL3144848CHEMBL300248 ZINC29481035 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030933 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm00402a036 10.7270/Q2KW5F21 2968456 Banzatti, C; Carfagna, N; Commisso, R; Heidempergher, F; Pegrassi, L; Melloni, P CNS Line http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030934 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00402a036 10.7270/Q2KW5F21 2968456 Banzatti, C; Carfagna, N; Commisso, R; Heidempergher, F; Pegrassi, L; Melloni, P CNS Line http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029858 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm00397a032 10.7270/Q25T3JGG 2892936 DeWald, HA; Beeson, NW; Hershenson, FM; Wise, LD; Downs, DA; Heffner, TG; Coughenour, LL; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029876 CCC1CN2C(=N1)c1c(N=C2C)c(C)nn1C InChI=1S/C12H17N5/c1-5-9-6-17-8(3)13-10-7(2)15-16(4)11(10)12(17)14-9/h9H,5-6H2,1-4H3 YFAVYALYCRERKH-UHFFFAOYSA-N 50019968 7-Ethyl-1,3,5-trimethyl-6,7-dihydro-1H-1,2,4,5a,8-pentaaza-as-indacene::CHEMBL143865 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00397a032 10.7270/Q25T3JGG 2892936 DeWald, HA; Beeson, NW; Hershenson, FM; Wise, LD; Downs, DA; Heffner, TG; Coughenour, LL; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019968&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 146009 103930891 CHEMBL143865 ZINC05933030 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029885 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029899 O=C1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1ncccc1-c1ccccc1 InChI=1S/C26H32N4O2S/c31-24-26(12-4-5-13-26)33-25(32)30(24)16-7-6-15-28-17-19-29(20-18-28)23-22(11-8-14-27-23)21-9-2-1-3-10-21/h1-3,8-11,14H,4-7,12-13,15-20H2 FUPHESAHOIDKIG-UHFFFAOYSA-N 50019986 3-{4-[4-(3-Phenyl-pyridin-2-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione::CHEMBL348578 D(2) dopamine receptor Rattus norvegicus 236 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019986&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14183680 103930909 CHEMBL348578 ZINC27704871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029900 Cc1nnc(o1)-c1cccnc1N1CCN(CCCCN2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C25H34N6O3/c1-19-27-28-24(34-19)20-7-6-10-26-23(20)30-15-13-29(14-16-30)11-4-5-12-31-21(32)17-25(18-22(31)33)8-2-3-9-25/h6-7,10H,2-5,8-9,11-18H2,1H3 KPWDDKVILBTFCD-UHFFFAOYSA-N 50019988 8-(4-{4-[3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-pyridin-2-yl]-piperazin-1-yl}-butyl)-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL158010 D(2) dopamine receptor Rattus norvegicus 610 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019988&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771049 103930911 CHEMBL158010 ZINC27706758 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029902 COC(=O)c1cccnc1N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C22H30N4O4S/c1-30-19(27)17-7-6-10-23-18(17)25-15-13-24(14-16-25)11-4-5-12-26-20(28)22(31-21(26)29)8-2-3-9-22/h6-7,10H,2-5,8-9,11-16H2,1H3 MZCOGVHKALYHMZ-UHFFFAOYSA-N 50019990 2-{4-[4-(2,4-Dioxo-1-thia-3-aza-spiro[4.4]non-3-yl)-butyl]-piperazin-1-yl}-nicotinic acid methyl ester::CHEMBL156549 D(2) dopamine receptor Rattus norvegicus 138 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019990&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771016 103930913 CHEMBL156549 ZINC27709218 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029903 Cc1cccnc1N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C21H30N4O2S/c1-17-7-6-10-22-18(17)24-15-13-23(14-16-24)11-4-5-12-25-19(26)21(28-20(25)27)8-2-3-9-21/h6-7,10H,2-5,8-9,11-16H2,1H3 VXRZEXSNWGRGGI-UHFFFAOYSA-N 50019992 3-{4-[4-(3-Methyl-pyridin-2-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione::CHEMBL157677 D(2) dopamine receptor Rattus norvegicus 630 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019992&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771020 103930915 CHEMBL157677 ZINC27706955 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029904 Cc1cccnc1N1CCN(CCCCN2C(=O)CC(C)(C)CC2=O)CC1 InChI=1S/C21H32N4O2/c1-17-7-6-8-22-20(17)24-13-11-23(12-14-24)9-4-5-10-25-18(26)15-21(2,3)16-19(25)27/h6-8H,4-5,9-16H2,1-3H3 WECVLPMJJAUVSU-UHFFFAOYSA-N 50019991 4,4-Dimethyl-1-{4-[4-(3-methyl-pyridin-2-yl)-piperazin-1-yl]-butyl}-piperidine-2,6-dione::CHEMBL155918 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019991&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771022 103930914 CHEMBL155918 ZINC27712598 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029905 [O-][N+](=O)c1cccnc1N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C20H27N5O4S/c26-18-20(7-1-2-8-20)30-19(27)24(18)11-4-3-10-22-12-14-23(15-13-22)17-16(25(28)29)6-5-9-21-17/h5-6,9H,1-4,7-8,10-15H2 WFEOSUOHPMGASR-UHFFFAOYSA-N 50019993 3-{4-[4-(3-Nitro-pyridin-2-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione::CHEMBL350035 D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14183678 103930916 CHEMBL350035 ZINC27715532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029906 CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2ncccc2Cl)C(=O)C1 InChI=1S/C20H29ClN4O2/c1-20(2)14-17(26)25(18(27)15-20)9-4-3-8-23-10-12-24(13-11-23)19-16(21)6-5-7-22-19/h5-7H,3-4,8-15H2,1-2H3 VXLBZLIRRKSIMG-UHFFFAOYSA-N 50019994 1-{4-[4-(3-Chloro-pyridin-2-yl)-piperazin-1-yl]-butyl}-4,4-dimethyl-piperidine-2,6-dione::CHEMBL348099 D(2) dopamine receptor Rattus norvegicus 360 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771024 103930917 CHEMBL348099 ZINC27711671 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029908 COc1cccc(n1)N1CCN(CCCCN2C(=O)CC(C)(C)CC2=O)CC1 InChI=1S/C21H32N4O3/c1-21(2)15-19(26)25(20(27)16-21)10-5-4-9-23-11-13-24(14-12-23)17-7-6-8-18(22-17)28-3/h6-8H,4-5,9-16H2,1-3H3 OBCWRHFHKMQBHO-UHFFFAOYSA-N 50019996 1-{4-[4-(6-Methoxy-pyridin-2-yl)-piperazin-1-yl]-butyl}-4,4-dimethyl-piperidine-2,6-dione::CHEMBL158302 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771035 103930919 CHEMBL158302 ZINC27706824 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029909 CO\N=C/c1cccnc1N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C22H31N5O3S/c1-30-24-17-18-7-6-10-23-19(18)26-15-13-25(14-16-26)11-4-5-12-27-20(28)22(31-21(27)29)8-2-3-9-22/h6-7,10,17H,2-5,8-9,11-16H2,1H3/b24-17- SULWINHUDLUHEP-ULJHMMPZSA-N 50019997 2-{4-[4-(2,4-Dioxo-1-thia-3-aza-spiro[4.4]non-3-yl)-butyl]-piperazin-1-yl}-pyridine-3-carbaldehyde O-methyl-oxime::CHEMBL158308 D(2) dopamine receptor Rattus norvegicus 428.0 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019997&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371003 103930920 CHEMBL158308 ZINC27704373 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029910 CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2ncccc2-c2ccccc2)C(=O)C1 InChI=1S/C26H34N4O2/c1-26(2)19-23(31)30(24(32)20-26)14-7-6-13-28-15-17-29(18-16-28)25-22(11-8-12-27-25)21-9-4-3-5-10-21/h3-5,8-12H,6-7,13-20H2,1-2H3 WXONACZIXYFYMN-UHFFFAOYSA-N 50019998 4,4-Dimethyl-1-{4-[4-(3-phenyl-pyridin-2-yl)-piperazin-1-yl]-butyl}-piperidine-2,6-dione::CHEMBL156285 D(2) dopamine receptor Rattus norvegicus 109 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019998&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14183683 103930921 CHEMBL156285 ZINC27711667 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029912 O=Cc1cccnc1N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C21H28N4O3S/c26-16-17-6-5-9-22-18(17)24-14-12-23(13-15-24)10-3-4-11-25-19(27)21(29-20(25)28)7-1-2-8-21/h5-6,9,16H,1-4,7-8,10-15H2 ZJBQDVPBSVJESO-UHFFFAOYSA-N 50019999 2-{4-[4-(2,4-Dioxo-1-thia-3-aza-spiro[4.4]non-3-yl)-butyl]-piperazin-1-yl}-pyridine-3-carbaldehyde::CHEMBL348377 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019999&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771014 103930922 CHEMBL348377 ZINC27711546 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029913 Nc1cccnc1N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C20H29N5O2S/c21-16-6-5-9-22-17(16)24-14-12-23(13-15-24)10-3-4-11-25-18(26)20(28-19(25)27)7-1-2-8-20/h5-6,9H,1-4,7-8,10-15,21H2 FHCGDVCJIXAEFB-UHFFFAOYSA-N 50020001 3-{4-[4-(3-Amino-pyridin-2-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione::CHEMBL347481 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020001&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371590 103930924 CHEMBL347481 ZINC27713290 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029914 Oc1csc(=O)n1CCCCN1CCN(CC1)c1ncccc1C#N InChI=1S/C17H21N5O2S/c18-12-14-4-3-5-19-16(14)21-10-8-20(9-11-21)6-1-2-7-22-15(23)13-25-17(22)24/h3-5,13,23H,1-2,6-11H2 OEVUGJNPERVHFY-UHFFFAOYSA-N 50020000 2-{4-[4-(2,4-Dioxo-thiazolidin-3-yl)-butyl]-piperazin-1-yl}-nicotinonitrile::CHEMBL156565 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020000&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54146638 103930923 CHEMBL156565 ZINC27713197 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029915 [O-][N+](=O)c1cccnc1N1CCN(CCCCN2C(=O)COCC2=O)CC1 InChI=1S/C17H23N5O5/c23-15-12-27-13-16(24)21(15)7-2-1-6-19-8-10-20(11-9-19)17-14(22(25)26)4-3-5-18-17/h3-5H,1-2,6-13H2 RTBFPRRGWFDRQC-UHFFFAOYSA-N 50019995 4-{4-[4-(3-Nitro-pyridin-2-yl)-piperazin-1-yl]-butyl}-morpholine-3,5-dione::CHEMBL156701 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771041 103930918 CHEMBL156701 ZINC27705595 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029918 O=C1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1ncccc1C#N InChI=1S/C21H27N5O2S/c22-16-17-6-5-9-23-18(17)25-14-12-24(13-15-25)10-3-4-11-26-19(27)21(29-20(26)28)7-1-2-8-21/h5-6,9H,1-4,7-8,10-15H2 BALZWNJGDNTUFK-UHFFFAOYSA-N 50020002 2-{4-[4-(2,4-Dioxo-1-thia-3-aza-spiro[4.4]non-3-yl)-butyl]-piperazin-1-yl}-nicotinonitrile::CHEMBL348150 D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020002&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135066 103930925 CHEMBL348150 ZINC27704521 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029919 COC(=O)c1cccnc1N1CCN(CCCCN2C(=O)CC(C)(C)CC2=O)CC1 InChI=1S/C22H32N4O4/c1-22(2)15-18(27)26(19(28)16-22)10-5-4-9-24-11-13-25(14-12-24)20-17(21(29)30-3)7-6-8-23-20/h6-8H,4-5,9-16H2,1-3H3 IUXBJUBDZZSWDM-UHFFFAOYSA-N 50019985 2-{4-[4-(4,4-Dimethyl-2,6-dioxo-piperidin-1-yl)-butyl]-piperazin-1-yl}-nicotinic acid methyl ester::CHEMBL155935 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019985&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771043 103930908 CHEMBL155935 ZINC27712153 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029920 COc1cccnc1N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C21H30N4O3S/c1-28-17-7-6-10-22-18(17)24-15-13-23(14-16-24)11-4-5-12-25-19(26)21(29-20(25)27)8-2-3-9-21/h6-7,10H,2-5,8-9,11-16H2,1H3 JELPGWKOZZCYSJ-UHFFFAOYSA-N 50020004 3-{4-[4-(3-Methoxy-pyridin-2-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione::CHEMBL346695 D(2) dopamine receptor Rattus norvegicus 79 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020004&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771018 103930927 CHEMBL346695 ZINC27707538 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029921 O=C1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1ccccn1 InChI=1S/C20H28N4O2S/c25-18-20(8-2-3-9-20)27-19(26)24(18)12-6-5-11-22-13-15-23(16-14-22)17-7-1-4-10-21-17/h1,4,7,10H,2-3,5-6,8-9,11-16H2 XJCLLYNUVSXDGL-UHFFFAOYSA-N 50020005 3-[4-(4-Pyridin-2-yl-piperazin-1-yl)-butyl]-1-thia-3-aza-spiro[4.4]nonane-2,4-dione::CHEMBL345600 D(2) dopamine receptor Rattus norvegicus 620 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020005&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371741 103930928 CHEMBL345600 ZINC27655451 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029922 Clc1cccnc1N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C20H27ClN4O2S/c21-16-6-5-9-22-17(16)24-14-12-23(13-15-24)10-3-4-11-25-18(26)20(28-19(25)27)7-1-2-8-20/h5-6,9H,1-4,7-8,10-15H2 PTBHTCKFKFQPHA-UHFFFAOYSA-N 50020003 3-{4-[4-(3-Chloro-pyridin-2-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione::CHEMBL349112 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020003&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771026 103930926 CHEMBL349112 ZINC27709213 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029925 COc1cccc(n1)N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C21H30N4O3S/c1-28-18-8-6-7-17(22-18)24-15-13-23(14-16-24)11-4-5-12-25-19(26)21(29-20(25)27)9-2-3-10-21/h6-8H,2-5,9-16H2,1H3 VHXGXZOTDILKRA-UHFFFAOYSA-N 50020006 3-{4-[4-(6-Methoxy-pyridin-2-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione::CHEMBL156354 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020006&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771033 103930929 CHEMBL156354 ZINC27707532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029927 Clc1cccnc1N1CCN(CCCCN2C(=O)COCC2=O)CC1 InChI=1S/C17H23ClN4O3/c18-14-4-3-5-19-17(14)21-10-8-20(9-11-21)6-1-2-7-22-15(23)12-25-13-16(22)24/h3-5H,1-2,6-13H2 ZCRKSGUDNFSNIX-UHFFFAOYSA-N 50019989 4-{4-[4-(3-Chloro-pyridin-2-yl)-piperazin-1-yl]-butyl}-morpholine-3,5-dione::CHEMBL155845 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019989&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771037 103930912 CHEMBL155845 ZINC27704387 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029931 Cc1cccnc1N1CCN(CCCCN2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C23H34N4O2/c1-19-7-6-10-24-22(19)26-15-13-25(14-16-26)11-4-5-12-27-20(28)17-23(18-21(27)29)8-2-3-9-23/h6-7,10H,2-5,8-9,11-18H2,1H3 UAMYAAMXKHZTHX-UHFFFAOYSA-N 50020008 8-{4-[4-(3-Methyl-pyridin-2-yl)-piperazin-1-yl]-butyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL158066 D(2) dopamine receptor Rattus norvegicus 476.0 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020008&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771030 103930931 CHEMBL158066 ZINC27706763 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029932 O=Cc1cccnc1N1CCN(CCCCN2C(=O)COCC2=O)CC1 InChI=1S/C18H24N4O4/c23-12-15-4-3-5-19-18(15)21-10-8-20(9-11-21)6-1-2-7-22-16(24)13-26-14-17(22)25/h3-5,12H,1-2,6-11,13-14H2 VRWHAGFNMQIDTP-UHFFFAOYSA-N 50020007 2-{4-[4-(3,5-Dioxo-morpholin-4-yl)-butyl]-piperazin-1-yl}-pyridine-3-carbaldehyde::CHEMBL434077 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020007&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13771039 103930930 CHEMBL434077 ZINC27706753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029933 O=C1COCC(=O)N1CCCCN1CCN(CC1)c1ncccc1-c1ccccc1 InChI=1S/C23H28N4O3/c28-21-17-30-18-22(29)27(21)12-5-4-11-25-13-15-26(16-14-25)23-20(9-6-10-24-23)19-7-2-1-3-8-19/h1-3,6-10H,4-5,11-18H2 ZYEYMMNRQTZSCP-UHFFFAOYSA-N 50019987 4-{4-[4-(3-Phenyl-pyridin-2-yl)-piperazin-1-yl]-butyl}-morpholine-3,5-dione::CHEMBL347631 D(2) dopamine receptor Rattus norvegicus >41 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14371235 103930910 CHEMBL347631 ZINC27704383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029934 Oc1csc(=O)n1CCCCN1CCN(CC1)c1ccccn1 InChI=1S/C16H22N4O2S/c21-15-13-23-16(22)20(15)8-4-3-7-18-9-11-19(12-10-18)14-5-1-2-6-17-14/h1-2,5-6,13,21H,3-4,7-12H2 GEASSBFJSTWXEZ-UHFFFAOYSA-N 50020009 3-[4-(4-Pyridin-2-yl-piperazin-1-yl)-butyl]-thiazolidine-2,4-dione::CHEMBL158359 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020009&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53833413 103930932 CHEMBL158359 ZINC27707199 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029935 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm00398a021 10.7270/Q2222SR2 2894466 New, JS; Yevich, JP; Temple, DL; New, KB; Gross, SM; Schlemmer, RF; Eison, MS; Taylor, DP; Riblet, LA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035719 CCc1ccc(cc1)N1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C19H23NO/c1-2-15-8-10-18(11-9-15)20-12-4-6-17(14-20)16-5-3-7-19(21)13-16/h3,5,7-11,13,17,21H,2,4,6,12,14H2,1H3/t17-/m0/s1 YGJRBOZFNLVISM-KRWDZBQOSA-N 50453369 CHEMBL48218 D(2) dopamine receptor Rattus norvegicus 90.0 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453369&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44293187 225145930 CHEMBL48218 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035721 CC(C)N1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-11(2)15-8-4-6-13(10-15)12-5-3-7-14(16)9-12/h3,5,7,9,11,13,16H,4,6,8,10H2,1-2H3/t13-/m0/s1 VRNBZJJBPKLDAO-ZDUSSCGKSA-N 50367444 CHEMBL432125 D(2) dopamine receptor Rattus norvegicus 1080 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937968 160846546 CHEMBL432125 ZINC13651752 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035722 CN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C12H17NO/c1-13-7-3-5-11(9-13)10-4-2-6-12(14)8-10/h2,4,6,8,11,14H,3,5,7,9H2,1H3/t11-/m1/s1 DKJJTEBJFLYIIS-LLVKDONJSA-N 50452349 CHEMBL46256 D(2) dopamine receptor Rattus norvegicus 290 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937959 225145662 CHEMBL46256 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035724 CC(C)N1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-11(2)15-8-4-6-13(10-15)12-5-3-7-14(16)9-12/h3,5,7,9,11,13,16H,4,6,8,10H2,1-2H3/t13-/m1/s1 VRNBZJJBPKLDAO-CYBMUJFWSA-N 50367442 CHEMBL424223 D(2) dopamine receptor Rattus norvegicus 450 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937970 160846544 CHEMBL424223 ZINC13651753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035725 CCN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C13H19NO/c1-2-14-8-4-6-12(10-14)11-5-3-7-13(15)9-11/h3,5,7,9,12,15H,2,4,6,8,10H2,1H3/t12-/m0/s1 GQOCTCQZVMEJSY-LBPRGKRZSA-N 50367447 CHEMBL47750 D(2) dopamine receptor Rattus norvegicus 540 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937962 160846549 CHEMBL47750 ZINC13651750 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035726 CN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C12H17NO/c1-13-7-3-5-11(9-13)10-4-2-6-12(14)8-10/h2,4,6,8,11,14H,3,5,7,9H2,1H3/t11-/m0/s1 DKJJTEBJFLYIIS-NSHDSACASA-N 50367446 CHEMBL49617 D(2) dopamine receptor Rattus norvegicus 610 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937957 160846548 CHEMBL49617 ZINC13651748 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035727 CCc1ccc(cc1)N1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C19H23NO/c1-2-15-8-10-18(11-9-15)20-12-4-6-17(14-20)16-5-3-7-19(21)13-16/h3,5,7-11,13,17,21H,2,4,6,12,14H2,1H3/t17-/m1/s1 YGJRBOZFNLVISM-QGZVFWFLSA-N 50453368 CHEMBL47900 D(2) dopamine receptor Rattus norvegicus 1360 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453368&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44293168 225145929 CHEMBL47900 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035729 CCCCN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m0/s1 ITXBDHMIXPKNIE-AWEZNQCLSA-N 50367443 CHEMBL45778 D(2) dopamine receptor Rattus norvegicus 430 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937973 160846545 CHEMBL45778 ZINC13651754 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035734 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 417 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035743 CCCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m1/s1 ITXBDHMIXPKNIE-CQSZACIVSA-N 50367440 CHEMBL48219 D(2) dopamine receptor Rattus norvegicus 560 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937975 160846542 CHEMBL48219 ZINC13651755 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035744 Oc1cccc(c1)[C@@H]1CCCNC1 InChI=1S/C11H15NO/c13-11-5-1-3-9(7-11)10-4-2-6-12-8-10/h1,3,5,7,10,12-13H,2,4,6,8H2/t10-/m1/s1 HYUOAVGLJXTEGX-SNVBAGLBSA-N 50452348 CHEMBL8033 D(2) dopamine receptor Rattus norvegicus 240 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937954 225145661 CHEMBL8033 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035745 CCCN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m0/s1 HTSNFXAICLXZMA-ZDUSSCGKSA-N 50010618 (+)-3-(1-Propyl-piperidin-3-yl)-phenol::3-((R)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(-)::CHEMBL7393::cid_202478 D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 202478 103923392 CHEMBL7393 ZINC00000393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035746 CCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C13H19NO/c1-2-14-8-4-6-12(10-14)11-5-3-7-13(15)9-11/h3,5,7,9,12,15H,2,4,6,8,10H2,1H3/t12-/m1/s1 GQOCTCQZVMEJSY-GFCCVEGCSA-N 50367445 CHEMBL49597 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937964 160846547 CHEMBL49597 ZINC13651751 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035749 Oc1cccc(c1)[C@H]1CCCNC1 InChI=1S/C11H15NO/c13-11-5-1-3-9(7-11)10-4-2-6-12-8-10/h1,3,5,7,10,12-13H,2,4,6,8H2/t10-/m0/s1 HYUOAVGLJXTEGX-JTQLQIEISA-N 50367441 CHEMBL8268 D(2) dopamine receptor Rattus norvegicus 360 ChEMBL 10.1021/jm00037a025 10.7270/Q25B0408 8201608 Seri-Levy, A; West, S; Richards, WG University of Oxford http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367441&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937952 160846543 CHEMBL8268 ZINC13651746 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035770 CCCN1CCc2cccc3-c4ccccc4C[C@@H]1c23 InChI=1S/C19H21N/c1-2-11-20-12-10-14-7-5-9-17-16-8-4-3-6-15(16)13-18(20)19(14)17/h3-9,18H,2,10-13H2,1H3/t18-/m1/s1 YUSPOIGOKXQAJK-GOSISDBHSA-N 50023737 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL31973 D(2) dopamine receptor Rattus norvegicus 2.4 ChEMBL 10.1021/jm00402a024 10.7270/Q2WW7GP2 3385732 Gao, Y; Zong, R; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948254 103934078 CHEMBL31973 ZINC02386801 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035772 CCCN1CCc2cccc3-c4ccccc4C[C@H]1c23 InChI=1S/C19H21N/c1-2-11-20-12-10-14-7-5-9-17-16-8-4-3-6-15(16)13-18(20)19(14)17/h3-9,18H,2,10-13H2,1H3/t18-/m0/s1 YUSPOIGOKXQAJK-SFHVURJKSA-N 50023738 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL27574 D(2) dopamine receptor Rattus norvegicus 115 ChEMBL 10.1021/jm00402a024 10.7270/Q2WW7GP2 3385732 Gao, Y; Zong, R; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023738&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44278589 103934079 CHEMBL27574 ZINC28771845 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035776 CCCN1CCc2cccc-3c2[C@@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m0/s1 WZJSIHGOLMMBAL-INIZCTEOSA-N 50023739 (S)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL283489 D(2) dopamine receptor Rattus norvegicus 105 ChEMBL 10.1021/jm00402a024 10.7270/Q2WW7GP2 3385732 Gao, Y; Zong, R; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023739&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13922235 103934080 CHEMBL283489 ZINC05833961 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50035778 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m1/s1 WZJSIHGOLMMBAL-MRXNPFEDSA-N 84636 CHEMBL27559::NPA-11-OH-R,(+) D(2) dopamine receptor Rattus norvegicus 2.7 ChEMBL 10.1021/jm00402a024 10.7270/Q2WW7GP2 3385732 Gao, Y; Zong, R; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333842 136350736 CHEMBL27559 ZINC05833984 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032632 NC[C@H]1O[C@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m1/s1 SUHGRZPINGKYNV-HUUCEWRRSA-N 50007136 1-Aminomethyl-3-phenyl-isochroman-5,6-diol::CHEMBL83080 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007136&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14809026 103920419 CHEMBL83080 ZINC04637270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032637 NCC1OCCc2c(O)c(O)ccc12 InChI=1S/C10H13NO3/c11-5-9-6-1-2-8(12)10(13)7(6)3-4-14-9/h1-2,9,12-13H,3-5,11H2 JBSRTZUQAXYSQB-UHFFFAOYSA-N 50010891 1-Aminomethyl-isochroman-5,6-diol::1-Aminomethyl-isochroman-5,6-diol; hydrobromide::CHEMBL542683::CHEMBL99361 D(2) dopamine receptor Rattus norvegicus 2850 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010891&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13864381 103923637 CHEMBL99361CHEMBL542683 ZINC11422304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032638 NCC1OCCc2c(O)c(O)ccc12 InChI=1S/C10H13NO3/c11-5-9-6-1-2-8(12)10(13)7(6)3-4-14-9/h1-2,9,12-13H,3-5,11H2 JBSRTZUQAXYSQB-UHFFFAOYSA-N 50010891 1-Aminomethyl-isochroman-5,6-diol::1-Aminomethyl-isochroman-5,6-diol; hydrobromide::CHEMBL542683::CHEMBL99361 D(2) dopamine receptor Rattus norvegicus 4610 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010891&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13864381 103923637 CHEMBL99361CHEMBL542683 ZINC11422304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032641 NC[C@H]1O[C@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m1/s1 SUHGRZPINGKYNV-HUUCEWRRSA-N 50007136 1-Aminomethyl-3-phenyl-isochroman-5,6-diol::CHEMBL83080 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007136&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14809026 103920419 CHEMBL83080 ZINC04637270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033454 CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1 InChI=1S/C21H25ClFN3O3/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27) YPELFRMCRYSPKZ-UHFFFAOYSA-N 94630 4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-morpholin-2-ylmethyl]-benzamide; citrate(AS-4370)::4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)morpholin-2-yl]methyl]benzamide;citric acid::4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid::4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid::4-azanyl-5-chloranyl-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-oxidanylpropane-1,2,3-tricarboxylic acid::CHEMBL60889::MLS001401439::MOSAPRIDE CITRATE::Mosapride::SMR000469200::cid_119583 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00106a023 10.7270/Q29887M5 1995885 Kato, S; Morie, T; Kon, T; Yoshida, N; Karasawa, T; Matsumoto, J Dainippon Pharmaceutical Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=94630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=94630&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 119584 164035874 CHEMBL60889 C13494 ZINC20621758 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50034649 CCCN(CCC)[C@H]1Cc2cccc3nc(O)n(C1)c23 InChI=1S/C16H23N3O.ClH/c1-3-8-18(9-4-2)13-10-12-6-5-7-14-15(12)19(11-13)16(20)17-14;/h5-7,13H,3-4,8-11H2,1-2H3,(H,17,20);1H/t13-;/m0./s1 WOIHACHAZHAFRL-ZOWNYOTGSA-N 50453287 CHEMBL2092845 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70697522 225145897 CHEMBL2092845 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50034650 OCCN1CCN(CC1)[C@@H]1C[C@H](c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2/t19-,21+/m0/s1 JSBWGXQXCRYYTG-PZJWPPBQSA-N 50019966 2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL95636::Tefludazine D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00084a014 10.7270/Q2Z89BB3 1348090 Perregaard, J; Arnt, J; Bogeso, KP; Hyttel, J; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71240 103930889 CHEMBL95636 ZINC22463345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50629532 NCC1OCCc2c(O)c(O)ccc12 InChI=1S/C10H13NO3/c11-5-9-6-1-2-8(12)10(13)7(6)3-4-14-9/h1-2,9,12-13H,3-5,11H2 JBSRTZUQAXYSQB-UHFFFAOYSA-N 50010891 1-Aminomethyl-isochroman-5,6-diol::1-Aminomethyl-isochroman-5,6-diol; hydrobromide::CHEMBL542683::CHEMBL99361 D(2) dopamine receptor Rattus norvegicus 2850 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010891&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13864381 103923637 CHEMBL99361CHEMBL542683 ZINC11422304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50629664 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1 SUHGRZPINGKYNV-GJZGRUSLSA-N 50007129 (1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol::1-Aminomethyl-3-phenyl-isochroman-5,6-diol::A-70108::CHEMBL86931 D(2) dopamine receptor Rattus norvegicus 776 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122324 103920412 CHEMBL86931 6077 ZINC03787668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50629665 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1 SUHGRZPINGKYNV-GJZGRUSLSA-N 50007129 (1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol::1-Aminomethyl-3-phenyl-isochroman-5,6-diol::A-70108::CHEMBL86931 D(2) dopamine receptor Rattus norvegicus 807 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122324 103920412 CHEMBL86931 6077 ZINC03787668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50629668 Oc1cc2CCNCC(c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2 JUDKOGFHZYMDMF-UHFFFAOYSA-N 50004923 (+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514 D(2) dopamine receptor Rattus norvegicus 6870 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1242 103918470 CHEMBL505308CHEMBL286080CHEMBL542700 935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50629669 Oc1cc2CCNCC(c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2 JUDKOGFHZYMDMF-UHFFFAOYSA-N 50004923 (+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1242 103918470 CHEMBL505308CHEMBL286080CHEMBL542700 935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50629670 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1 SUHGRZPINGKYNV-GJZGRUSLSA-N 50007129 (1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol::1-Aminomethyl-3-phenyl-isochroman-5,6-diol::A-70108::CHEMBL86931 D(2) dopamine receptor Rattus norvegicus 10200 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122324 103920412 CHEMBL86931 6077 ZINC03787668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50629680 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1 SUHGRZPINGKYNV-GJZGRUSLSA-N 50007129 (1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol::1-Aminomethyl-3-phenyl-isochroman-5,6-diol::A-70108::CHEMBL86931 D(2) dopamine receptor Rattus norvegicus 10200 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122324 103920412 CHEMBL86931 6077 ZINC03787668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032505 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Rattus norvegicus 183 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032508 CCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C11H17N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h4,8H,2-3,5-7H2,1H3,(H2,12,13) VJPANQWIZQHGMJ-UHFFFAOYSA-N 50007573 4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazol-2-ylamine::CHEMBL93428 D(2) dopamine receptor Rattus norvegicus 958 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 194775 103920843 CHEMBL93428 ZINC13209017 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032509 CCCN1CCC=C(C1)c1csc(NC)n1 InChI=1S/C12H19N3S/c1-3-6-15-7-4-5-10(8-15)11-9-16-12(13-2)14-11/h5,9H,3-4,6-8H2,1-2H3,(H,13,14) PYYWPVKGPXCJDC-UHFFFAOYSA-N 50010571 CHEMBL108682::Methyl-[4-(1-propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazol-2-yl]-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823145 103923347 CHEMBL108682 ZINC26938695 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032511 CCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C10H15N3S/c1-2-13-5-3-4-8(6-13)9-7-14-10(11)12-9/h4,7H,2-3,5-6H2,1H3,(H2,11,12) CSGZCYPSSIETMO-UHFFFAOYSA-N 50010573 4-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazol-2-ylamine::CHEMBL106028 D(2) dopamine receptor Rattus norvegicus 411 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823129 103923349 CHEMBL106028 ZINC26845072 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032515 CC(C)CCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C13H21N3S/c1-10(2)5-7-16-6-3-4-11(8-16)12-9-17-13(14)15-12/h4,9-10H,3,5-8H2,1-2H3,(H2,14,15) SBAYDHJDGKVZBW-UHFFFAOYSA-N 50367939 CHEMBL1203002 D(2) dopamine receptor Rattus norvegicus 2690 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823138 160847041 CHEMBL1203002 ZINC26845861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032518 Nc1nc(cs1)C1=CCCN(CC=C)C1 InChI=1S/C11H15N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h2,4,8H,1,3,5-7H2,(H2,12,13) JMEQXIANNKFBTB-UHFFFAOYSA-N 50010580 4-(1-Allyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazol-2-ylamine::CHEMBL106257 D(2) dopamine receptor Rattus norvegicus 257 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010580&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 194776 103923356 CHEMBL106257 ZINC13208878 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033625 COc1ccc(Br)c(O)c1C(=O)NC[C@H]1CCCN1Cc1ccccc1 InChI=1S/C20H23BrN2O3/c1-26-17-10-9-16(21)19(24)18(17)20(25)22-12-15-8-5-11-23(15)13-14-6-3-2-4-7-14/h2-4,6-7,9-10,15,24H,5,8,11-13H2,1H3,(H,22,25)/t15-/m1/s1 MBIMLBIDRSPVIF-OAHLLOKOSA-N 50453039 CHEMBL2096749 D(2) dopamine receptor Rattus norvegicus 18.0 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894146 225145822 CHEMBL2096749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033627 COc1ccc(Br)c(O)c1C(=O)NC[C@H]1CCCN1Cc1ccc(F)cc1 InChI=1S/C20H22BrFN2O3/c1-27-17-9-8-16(21)19(25)18(17)20(26)23-11-15-3-2-10-24(15)12-13-4-6-14(22)7-5-13/h4-9,15,25H,2-3,10-12H2,1H3,(H,23,26)/t15-/m1/s1 PQAIFVHATFSBMU-OAHLLOKOSA-N 50007524 (R) 3-Bromo-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2-hydroxy-6-methoxy-benzamide::CHEMBL175082 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007524&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894152 103920799 CHEMBL175082 ZINC13820604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033630 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 0.550000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033632 CCN1CCC[C@H]1CNC(=O)c1c(OC)c(Cl)cc(Cl)c1OC InChI=1S/C16H22Cl2N2O3/c1-4-20-7-5-6-10(20)9-19-16(21)13-14(22-2)11(17)8-12(18)15(13)23-3/h8,10H,4-7,9H2,1-3H3,(H,19,21)/t10-/m0/s1 JGQKBQNMKHVABS-JTQLQIEISA-N 50007509 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::CHEMBL171921 D(2) dopamine receptor Rattus norvegicus 0.150000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10689922 103920784 CHEMBL171921 ZINC02021795 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032627 NCC1OCCc2c(O)c(O)ccc12 InChI=1S/C10H13NO3/c11-5-9-6-1-2-8(12)10(13)7(6)3-4-14-9/h1-2,9,12-13H,3-5,11H2 JBSRTZUQAXYSQB-UHFFFAOYSA-N 50010891 1-Aminomethyl-isochroman-5,6-diol::1-Aminomethyl-isochroman-5,6-diol; hydrobromide::CHEMBL542683::CHEMBL99361 D(2) dopamine receptor Rattus norvegicus 4610 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010891&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13864381 103923637 CHEMBL99361CHEMBL542683 ZINC11422304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032630 NC[C@H]1O[C@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m1/s1 SUHGRZPINGKYNV-HUUCEWRRSA-N 50007136 1-Aminomethyl-3-phenyl-isochroman-5,6-diol::CHEMBL83080 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007136&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14809026 103920419 CHEMBL83080 ZINC04637270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032635 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1 SUHGRZPINGKYNV-GJZGRUSLSA-N 50007129 (1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol::1-Aminomethyl-3-phenyl-isochroman-5,6-diol::A-70108::CHEMBL86931 D(2) dopamine receptor Rattus norvegicus 776 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122324 103920412 CHEMBL86931 6077 ZINC03787668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032640 Oc1cc2CCNCC(c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2 JUDKOGFHZYMDMF-UHFFFAOYSA-N 50004923 (+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514 D(2) dopamine receptor Rattus norvegicus 6870 ChEMBL 10.1021/jm00173a005 10.7270/Q2QV3N4J 1977907 DeNinno, MP; Schoenleber, R; Asin, KE; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1242 103918470 CHEMBL505308CHEMBL286080CHEMBL542700 935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015695 Oc1cccc(c1)C1CCCN2CCCCC12 InChI=1S/C15H21NO/c17-13-6-3-5-12(11-13)14-7-4-10-16-9-2-1-8-15(14)16/h3,5-6,11,14-15,17H,1-2,4,7-10H2 RUTLNJGVITWMQE-UHFFFAOYSA-N 50010614 3-(Octahydro-quinolizin-1-yl)-phenol::CHEMBL7381::isomer-13-(Octahydro-quinolizin-1-yl)-phenol::isomer-23-(Octahydro-quinolizin-1-yl)-phenol D(2) dopamine receptor Rattus norvegicus 580 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720739 103923388 CHEMBL7381 ZINC34133358 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015699 Oc1cccc(c1)C1=CCCN2CCCCC12 InChI=1S/C15H19NO/c17-13-6-3-5-12(11-13)14-7-4-10-16-9-2-1-8-15(14)16/h3,5-7,11,15,17H,1-2,4,8-10H2 UTPPZLWOQNHIMZ-UHFFFAOYSA-N 50010615 3-(3,6,7,8,9,9a-Hexahydro-4H-quinolizin-1-yl)-phenol::CHEMBL7449 D(2) dopamine receptor Rattus norvegicus 320 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010615&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720735 103923389 CHEMBL7449 ZINC25974459 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015700 Oc1cccc(c1)[C@H]1CCCN2CCCC12 InChI=1S/C14H19NO/c16-12-5-1-4-11(10-12)13-6-2-8-15-9-3-7-14(13)15/h1,4-5,10,13-14,16H,2-3,6-9H2/t13-,14?/m1/s1 WOXUXMJHVREOKX-KWCCSABGSA-N 50010613 3-(Octahydro-indolizin-8-yl)-phenol::CHEMBL7850 D(2) dopamine receptor Rattus norvegicus 4900 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010613&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720757 103923387 CHEMBL7850 ZINC25976231 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015704 Oc1cccc(c1)C1CCC2CCCCN2C1 InChI=1S/C15H21NO.C2H2O4/c17-15-6-3-4-12(10-15)13-7-8-14-5-1-2-9-16(14)11-13;3-1(4)2(5)6/h3-4,6,10,13-14,17H,1-2,5,7-9,11H2;(H,3,4)(H,5,6) IXLZJCYTLAFFMV-UHFFFAOYSA-N 50452756 CHEMBL2051756 D(2) dopamine receptor Rattus norvegicus 7900 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452756&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70686325 225145739 CHEMBL2051756 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032769 Oc1cccc(c1)[C@@H]1CCCN2CCCC12 InChI=1S/C14H19NO/c16-12-5-1-4-11(10-12)13-6-2-8-15-9-3-7-14(13)15/h1,4-5,10,13-14,16H,2-3,6-9H2/t13-,14?/m0/s1 WOXUXMJHVREOKX-LSLKUGRBSA-N 50010620 3-(Octahydro-indolizin-8-yl)-phenol::CHEMBL8074 D(2) dopamine receptor Rattus norvegicus 6500 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010620&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720755 103923394 CHEMBL8074 ZINC25979588 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032770 Oc1cccc(c1)C1CCCN2CCCC12 InChI=1S/C14H19NO/c16-12-5-1-4-11(10-12)13-6-2-8-15-9-3-7-14(13)15/h1,4-5,10,13-14,16H,2-3,6-9H2 WOXUXMJHVREOKX-UHFFFAOYSA-N 50010616 (+)-3-(Octahydro-indolizin-8-yl)-phenol::(-)-3-(Octahydro-indolizin-8-yl)-phenol::3-(Octahydro-indolizin-8-yl)-phenol::CHEMBL268240::isomer-13-(Octahydro-indolizin-8-yl)-phenol::isomer-23-(Octahydro-indolizin-8-yl)-phenol D(2) dopamine receptor Rattus norvegicus 3800 ChEMBL 10.1021/jm00165a020 10.7270/Q2PV6JBT 1968512 Liljefors, T; Bogeso, KP; Hyttel, J; Wikstrom, H; Svensson, K; Carlsson, A University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010616&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13720753 103923390 CHEMBL268240 ZINC25979781 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033876 Fc1ccc(cc1)C(=O)C1CCN(CC2CC(=O)c3ccccc3C2)CC1 InChI=1S/C23H24FNO2/c24-20-7-5-17(6-8-20)23(27)18-9-11-25(12-10-18)15-16-13-19-3-1-2-4-21(19)22(26)14-16/h1-8,16,18H,9-15H2 JFVJCLYJXOVMSI-UHFFFAOYSA-N 50409510 CHEMBL308480 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00111a046 10.7270/Q2930VPR 1676759 Cortizo, L; Santana, L; Ravina, E; Orallo, F; Fontenla, JA; Castro, E; Calleja, JM; de Ceballos, ML University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15021876 163358534 CHEMBL308480 ZINC12356211 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033878 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00111a046 10.7270/Q2930VPR 1676759 Cortizo, L; Santana, L; Ravina, E; Orallo, F; Fontenla, JA; Castro, E; Calleja, JM; de Ceballos, ML University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033879 Fc1ccc(cc1)C(=O)CCCN1CCN(CC2CC(=O)c3ccccc3C2)CC1 InChI=1S/C25H29FN2O2/c26-22-9-7-20(8-10-22)24(29)6-3-11-27-12-14-28(15-13-27)18-19-16-21-4-1-2-5-23(21)25(30)17-19/h1-2,4-5,7-10,19H,3,6,11-18H2 WIVGCTVBLDUZMD-UHFFFAOYSA-N 50409493 CHEMBL310734 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00111a046 10.7270/Q2930VPR 1676759 Cortizo, L; Santana, L; Ravina, E; Orallo, F; Fontenla, JA; Castro, E; Calleja, JM; de Ceballos, ML University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10386748 163358517 CHEMBL310734 ZINC22925153 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033880 COc1ccccc1N1CCN(CC2CC(=O)c3ccccc3C2)CC1 InChI=1S/C22H26N2O2/c1-26-22-9-5-4-8-20(22)24-12-10-23(11-13-24)16-17-14-18-6-2-3-7-19(18)21(25)15-17/h2-9,17H,10-16H2,1H3 UMEYBQLIJXNFOT-UHFFFAOYSA-N 50409503 CHEMBL310153 D(2) dopamine receptor Rattus norvegicus 6.5 ChEMBL 10.1021/jm00111a046 10.7270/Q2930VPR 1676759 Cortizo, L; Santana, L; Ravina, E; Orallo, F; Fontenla, JA; Castro, E; Calleja, JM; de Ceballos, ML University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15021875 163358527 CHEMBL310153 ZINC13471608 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033882 OC1(CCN(CC2CC(=O)c3ccccc3C2)CC1)c1ccccc1 InChI=1S/C22H25NO2/c24-21-15-17(14-18-6-4-5-9-20(18)21)16-23-12-10-22(25,11-13-23)19-7-2-1-3-8-19/h1-9,17,25H,10-16H2 QXPWDQWINFEIAQ-UHFFFAOYSA-N 50453056 CHEMBL73675 D(2) dopamine receptor Rattus norvegicus 74 ChEMBL 10.1021/jm00111a046 10.7270/Q2930VPR 1676759 Cortizo, L; Santana, L; Ravina, E; Orallo, F; Fontenla, JA; Castro, E; Calleja, JM; de Ceballos, ML University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453056&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15691846 225145833 CHEMBL73675 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033897 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033900 Fc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24FN3O2S/c24-19-8-10-20(11-9-19)26-16-14-25(15-17-26)12-3-13-27-21-6-1-4-18-5-2-7-22(23(18)21)30(27,28)29/h1-2,4-11H,3,12-17H2 VGIGHGMPMUCLIQ-UHFFFAOYSA-N 50010044 2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)::2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide(Fananserin)::CHEMBL83894::ChEMBL_131689::FANANSERIN D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60785 103922972 CHEMBL83894 5434 ZINC00597400 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031697 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032844 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 WGLPSCZHULDZSS-JTQLQIEISA-N 50007517 (S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-5,6-dimethoxybenzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-5,6-dimethoxy-benzamide::CHEMBL76402 D(2) dopamine receptor Rattus norvegicus 0.064000 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977478 103920792 CHEMBL76402 ZINC03776019 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032846 CCCc1cc(OC)c(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1O InChI=1S/C19H30N2O4/c1-5-8-13-11-15(24-3)18(25-4)16(17(13)22)19(23)20-12-14-9-7-10-21(14)6-2/h11,14,22H,5-10,12H2,1-4H3,(H,20,23)/t14-/m0/s1 XGLIHZCJAFMECG-AWEZNQCLSA-N 50368060 CHEMBL1907695 D(2) dopamine receptor Rattus norvegicus 0.023000 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368060&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668308 160847162 CHEMBL1907695 ZINC13821895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032847 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 0.550000 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032848 CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(OC)c1OC InChI=1S/C16H24N2O4/c1-4-18-9-5-6-11(18)10-17-16(20)14-12(19)7-8-13(21-2)15(14)22-3/h7-8,11,19H,4-6,9-10H2,1-3H3,(H,17,20)/t11-/m0/s1 DQDAHRKHWVTGOB-NSHDSACASA-N 50010724 CHEMBL305916::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.750000 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14416355 103923470 CHEMBL305916 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032850 CCN1CCC[C@@H]1CNC(=O)c1c(O)c(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m1/s1 WGLPSCZHULDZSS-SNVBAGLBSA-N 50368062 CHEMBL1907915 D(2) dopamine receptor Rattus norvegicus 6.5 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368062&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668294 160847164 CHEMBL1907915 ZINC00575720 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032851 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(OC)c1OC InChI=1S/C16H23ClN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 DVNOGBDQNYJXJS-JTQLQIEISA-N 50368065 CHEMBL1907692 D(2) dopamine receptor Rattus norvegicus 0.087000 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668289 160847167 CHEMBL1907692 ZINC34343065 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032852 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032853 CCN1CCC[C@H]1CNC(=O)c1c(O)c(OC)cc(Br)c1OC InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)12(22-2)8-11(17)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 UFZPFNGITSAOBL-JTQLQIEISA-N 50368073 CHEMBL1907690 D(2) dopamine receptor Rattus norvegicus 8.4 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368073&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668296 160847175 CHEMBL1907690 ZINC34343069 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032854 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(OC)c1OC InChI=1S/C18H28N2O4/c1-5-12-10-14(23-3)17(24-4)15(16(12)21)18(22)19-11-13-8-7-9-20(13)6-2/h10,13,21H,5-9,11H2,1-4H3,(H,19,22)/t13-/m0/s1 NHGHSSSIIOPHJZ-ZDUSSCGKSA-N 50368067 CHEMBL1907702 D(2) dopamine receptor Rattus norvegicus 0.033000 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668300 160847169 CHEMBL1907702 ZINC34343070 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033954 CCCN1CCC=C2C1CCc1sc(N)nc21 InChI=1S/C13H19N3S/c1-2-7-16-8-3-4-9-10(16)5-6-11-12(9)15-13(14)17-11/h4,10H,2-3,5-8H2,1H3,(H2,14,15) VOPHHPYKMCJUCP-UHFFFAOYSA-N 50007571 6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-2-ylamine::CHEMBL91453 D(2) dopamine receptor Rattus norvegicus 860 ChEMBL 10.1021/jm00113a010 10.7270/Q2V125FC 1680195 Caprathe, BW; Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT; Parvez, M Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14233815 103920841 CHEMBL91453 ZINC13824112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031793 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC[C@@H](C)O InChI=1S/C16H26ClN3O3/c1-4-20(5-2)7-6-19-16(22)12-8-13(17)14(18)9-15(12)23-10-11(3)21/h8-9,11,21H,4-7,10,18H2,1-3H3,(H,19,22)/t11-/m1/s1 GATCOSFCYSJURA-LLVKDONJSA-N 50452525 CHEMBL2114431 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116909 225145705 CHEMBL2114431 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031794 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(=O)Cc1ccccc1 InChI=1S/C22H28ClN3O3/c1-3-26(4-2)11-10-25-22(28)18-13-19(23)20(24)14-21(18)29-15-17(27)12-16-8-6-5-7-9-16/h5-9,13-14H,3-4,10-12,15,24H2,1-2H3,(H,25,28) XIKNRONEPQCKTI-UHFFFAOYSA-N 50452526 CHEMBL2114428 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452526&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116896 225145706 CHEMBL2114428 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033051 CCN1CCC[C@H]1CNC(=O)c1cc(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 QAECXZXKVURFMR-LBPRGKRZSA-N 50007522 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide::5-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2,3-dimethoxybenzamide::CHEMBL289330 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9907436 103920797 CHEMBL289330 ZINC03780178 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033052 CCN1CCC[C@@H]1CNC(=O)c1cc(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m1/s1 QAECXZXKVURFMR-GFCCVEGCSA-N 50452879 CHEMBL2114141 D(2) dopamine receptor Rattus norvegicus 145 ChEMBL 10.1021/jm00170a040 10.7270/Q29P30MH 1973734 Hogberg, T; de Paulis, T; Johansson, L; Kumar, Y; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452879&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14665494 225145744 CHEMBL2114141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033211 CCCCCCN1CCC[C@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O InChI=1S/C21H33N3O4S/c1-3-4-5-6-9-24-10-7-8-17(24)14-23-21(25)19-13-18(29(22,26)27)12-16-11-15(2)28-20(16)19/h12-13,15,17H,3-11,14H2,1-2H3,(H,23,25)(H2,22,26,27)/t15-,17-/m0/s1 SHWNENMUVQNYBC-RDJZCZTQSA-N 50452986 CHEMBL2115227 D(2) dopamine receptor Rattus norvegicus 630 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452986&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14879096 225145797 CHEMBL2115227 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033212 CCCCN1CCC[C@H]1CNC(=O)c1cc(cc2C[C@@H](C)Oc12)S(N)(=O)=O InChI=1S/C19H29N3O4S/c1-3-4-7-22-8-5-6-15(22)12-21-19(23)17-11-16(27(20,24)25)10-14-9-13(2)26-18(14)17/h10-11,13,15H,3-9,12H2,1-2H3,(H,21,23)(H2,20,24,25)/t13-,15+/m1/s1 ITVVMWXAZTUXIL-HIFRSBDPSA-N 50452987 CHEMBL2115228 D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13420585 225145798 CHEMBL2115228 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033213 CCCCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C17H27N3O4S/c1-3-4-9-20-10-5-6-13(20)12-19-17(21)15-11-14(25(18,22)23)7-8-16(15)24-2/h7-8,11,13H,3-6,9-10,12H2,1-2H3,(H,19,21)(H2,18,22,23)/t13-/m1/s1 OBOHWJBYXZNLJD-CYBMUJFWSA-N 50284609 CHEMBL278762::N-((R)-1-Butyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoyl-benzamide D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284609&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12771208 104126180 CHEMBL278762 ZINC13860949 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033214 CCCCN1CCC[C@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O InChI=1S/C19H29N3O4S/c1-3-4-7-22-8-5-6-15(22)12-21-19(23)17-11-16(27(20,24)25)10-14-9-13(2)26-18(14)17/h10-11,13,15H,3-9,12H2,1-2H3,(H,21,23)(H2,20,24,25)/t13-,15-/m0/s1 ITVVMWXAZTUXIL-ZFWWWQNUSA-N 50452982 CHEMBL2115229 D(2) dopamine receptor Rattus norvegicus 95 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452982&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13420583 225145793 CHEMBL2115229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033215 CCCCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C17H27N3O4S/c1-3-4-9-20-10-5-6-13(20)12-19-17(21)15-11-14(25(18,22)23)7-8-16(15)24-2/h7-8,11,13H,3-6,9-10,12H2,1-2H3,(H,19,21)(H2,18,22,23)/t13-/m0/s1 OBOHWJBYXZNLJD-ZDUSSCGKSA-N 50284586 CHEMBL22857::N-((S)-1-Butyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoyl-benzamide D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12771209 104126157 CHEMBL22857 ZINC13860948 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033216 CCN1CCC[C@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O InChI=1S/C17H25N3O4S/c1-3-20-6-4-5-13(20)10-19-17(21)15-9-14(25(18,22)23)8-12-7-11(2)24-16(12)15/h8-9,11,13H,3-7,10H2,1-2H3,(H,19,21)(H2,18,22,23)/t11-,13-/m0/s1 KYDXJSDWCPSSJZ-AAEUAGOBSA-N 50452981 CHEMBL2115231 D(2) dopamine receptor Rattus norvegicus 9.6 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452981&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13420577 225145792 CHEMBL2115231 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033217 CCN1CCC[C@@H]1CNC(=O)c1cc(cc2C[C@@H](C)Oc12)S(N)(=O)=O InChI=1S/C17H25N3O4S/c1-3-20-6-4-5-13(20)10-19-17(21)15-9-14(25(18,22)23)8-12-7-11(2)24-16(12)15/h8-9,11,13H,3-7,10H2,1-2H3,(H,19,21)(H2,18,22,23)/t11-,13-/m1/s1 KYDXJSDWCPSSJZ-DGCLKSJQSA-N 50452989 CHEMBL2114239 D(2) dopamine receptor Rattus norvegicus 650 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452989&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13420578 225145800 CHEMBL2114239 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033218 CCCCCCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C19H31N3O4S/c1-3-4-5-6-11-22-12-7-8-15(22)14-21-19(23)17-13-16(27(20,24)25)9-10-18(17)26-2/h9-10,13,15H,3-8,11-12,14H2,1-2H3,(H,21,23)(H2,20,24,25)/t15-/m0/s1 ARSAADUCGPEJRE-HNNXBMFYSA-N 50452979 CHEMBL2115233 D(2) dopamine receptor Rattus norvegicus 1400 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452979&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14879093 225145790 CHEMBL2115233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033219 CCN1CCC[C@@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O InChI=1S/C17H25N3O4S/c1-3-20-6-4-5-13(20)10-19-17(21)15-9-14(25(18,22)23)8-12-7-11(2)24-16(12)15/h8-9,11,13H,3-7,10H2,1-2H3,(H,19,21)(H2,18,22,23)/t11-,13+/m0/s1 KYDXJSDWCPSSJZ-WCQYABFASA-N 50452988 CHEMBL2114238 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452988&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13420576 225145799 CHEMBL2114238 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033220 CCCCCCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C19H31N3O4S/c1-3-4-5-6-11-22-12-7-8-15(22)14-21-19(23)17-13-16(27(20,24)25)9-10-18(17)26-2/h9-10,13,15H,3-8,11-12,14H2,1-2H3,(H,21,23)(H2,20,24,25)/t15-/m1/s1 ARSAADUCGPEJRE-OAHLLOKOSA-N 50452990 CHEMBL2114240 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452990&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14879092 225145801 CHEMBL2114240 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033221 CCN1CCC[C@H]1CNC(=O)c1cc(cc2C[C@@H](C)Oc12)S(N)(=O)=O InChI=1S/C17H25N3O4S/c1-3-20-6-4-5-13(20)10-19-17(21)15-9-14(25(18,22)23)8-12-7-11(2)24-16(12)15/h8-9,11,13H,3-7,10H2,1-2H3,(H,19,21)(H2,18,22,23)/t11-,13+/m1/s1 KYDXJSDWCPSSJZ-YPMHNXCESA-N 50452980 CHEMBL2115232 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452980&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13420579 225145791 CHEMBL2115232 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033222 CCCCN1CCC[C@@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O InChI=1S/C19H29N3O4S/c1-3-4-7-22-8-5-6-15(22)12-21-19(23)17-11-16(27(20,24)25)10-14-9-13(2)26-18(14)17/h10-11,13,15H,3-9,12H2,1-2H3,(H,21,23)(H2,20,24,25)/t13-,15+/m0/s1 ITVVMWXAZTUXIL-DZGCQCFKSA-N 50452983 CHEMBL2114236 D(2) dopamine receptor Rattus norvegicus 9.4 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452983&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13420582 225145794 CHEMBL2114236 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033223 CCCCN1CCC[C@@H]1CNC(=O)c1cc(cc2C[C@@H](C)Oc12)S(N)(=O)=O InChI=1S/C19H29N3O4S/c1-3-4-7-22-8-5-6-15(22)12-21-19(23)17-11-16(27(20,24)25)10-14-9-13(2)26-18(14)17/h10-11,13,15H,3-9,12H2,1-2H3,(H,21,23)(H2,20,24,25)/t13-,15-/m1/s1 ITVVMWXAZTUXIL-UKRRQHHQSA-N 50452984 CHEMBL2114235 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452984&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13420584 225145795 CHEMBL2114235 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033224 CCCCCCN1CCC[C@@H]1CNC(=O)c1cc(cc2C[C@H](C)Oc12)S(N)(=O)=O InChI=1S/C21H33N3O4S/c1-3-4-5-6-9-24-10-7-8-17(24)14-23-21(25)19-13-18(29(22,26)27)12-16-11-15(2)28-20(16)19/h12-13,15,17H,3-11,14H2,1-2H3,(H,23,25)(H2,22,26,27)/t15-,17+/m0/s1 SHWNENMUVQNYBC-DOTOQJQBSA-N 50452985 CHEMBL2114234 D(2) dopamine receptor Rattus norvegicus 6.7 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452985&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14879095 225145796 CHEMBL2114234 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50034393 CCCCCN1CC[C@]2(C)[C@H](C)C1Cc1ccc(O)cc21 InChI=1S/C19H29NO/c1-4-5-6-10-20-11-9-19(3)14(2)18(20)12-15-7-8-16(21)13-17(15)19/h7-8,13-14,18,21H,4-6,9-12H2,1-3H3/t14-,18?,19-/m1/s1 XPPRDCVATUTJON-LVYUKURTSA-N 50037480 (6R,11S)-6,11-Dimethyl-3-pentyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL324392 D(2) dopamine receptor Rattus norvegicus 2533 ChEMBL 10.1021/jm00090a012 10.7270/Q24B31ZD 1319493 de Costa, B; Radesca, L; Dominguez, C; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037480&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44342741 103945027 CHEMBL324392 ZINC27086942 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50034445 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Rattus norvegicus 0.120000 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50034446 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 170 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50034450 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 9.5 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50034451 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) BVPWJMCABCPUQY-UHFFFAOYSA-N 50132693 4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide(Clebopride)::4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide::CHEMBL325109::Clebopride D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2780 104023670 CHEMBL325109 ZINC00608261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50037002 C([C@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m0/s1 XBGWTWPYCTZIIE-FQEVSTJZSA-N 50453436 CHEMBL2111778 D(2) dopamine receptor Rattus norvegicus 113 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9973858 225145940 CHEMBL2111778 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50037003 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50037006 C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1 XBGWTWPYCTZIIE-HXUWFJFHSA-N 50048299 4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL335545::CI-1007 D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127698 103978825 CHEMBL335545 ZINC03792322 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50037008 C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1 XBGWTWPYCTZIIE-HXUWFJFHSA-N 50048299 4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL335545::CI-1007 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127698 103978825 CHEMBL335545 ZINC03792322 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50037009 C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2/t20-/m1/s1 XBGWTWPYCTZIIE-HXUWFJFHSA-N 50048299 4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL335545::CI-1007 D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127698 103978825 CHEMBL335545 ZINC03792322 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50039464 CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C27H37N3O3.H2O/c1-4-11-29(12-5-6-13-30-24(32)15-27(2,3)16-25(30)33)21-9-7-19-8-10-23-26(22(19)14-21)20(18-31)17-28-23;/h8,10,17-18,21,28H,4-7,9,11-16H2,1-3H3;1H2/t21-;/m0./s1 CHUHEUVYBZLIPW-BOXHHOBZSA-N 50453697 CHEMBL2112317 D(2) dopamine receptor Rattus norvegicus 859 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453697&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71452688 225146089 CHEMBL2112317 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50036256 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Rattus norvegicus 87.7 ChEMBL 10.1021/jm00041a025 10.7270/Q2KS6QKD 7914538 Knoerzer, TA; Nichols, DE; Brewster, WK; Watts, VJ; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50036388 O=C1C2CCCCC2C=NN1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H31N5OS/c29-23-19-8-2-1-7-18(19)17-24-28(23)12-6-5-11-26-13-15-27(16-14-26)22-20-9-3-4-10-21(20)30-25-22/h3-4,9-10,17-19H,1-2,5-8,11-16H2 BBONTYVGVUFBBF-UHFFFAOYSA-N 50036920 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one::CHEMBL83625 D(2) dopamine receptor Rattus norvegicus 10.0 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036920&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15183280 103944561 CHEMBL83625 ZINC26572457 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50036417 FC(F)(F)S(=O)(=O)Oc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12 InChI=1S/C16H18F3NO3S/c1-2-9-20-10-8-12-11-4-3-5-15(13(11)6-7-14(12)20)23-24(21,22)16(17,18)19/h2-5,12,14H,1,6-10H2/t12-,14+/m1/s1 JNAGEIMWCSOQKU-OCCSQVGLSA-N 50453388 CHEMBL2111566 D(2) dopamine receptor Rattus norvegicus >172 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453388&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10428654 225145937 CHEMBL2111566 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50036432 CN(C)CCCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C17H25N3/c1-19(2)9-5-11-20-10-4-8-17(14-20)16-7-3-6-15(12-16)13-18/h3,6-7,12,17H,4-5,8-11,14H2,1-2H3/t17-/m1/s1 AKBLTSXPRUVMOS-QGZVFWFLSA-N 50039754 3-[(S)-1-(3-Dimethylamino-propyl)-piperidin-3-yl]-benzonitrile::CHEMBL327836 D(2) dopamine receptor Rattus norvegicus >217 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039754&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10084584 103946949 CHEMBL327836 ZINC13738281 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50037503 Oc1ccc2c(c1)[nH]c(=O)n(CCN1CCC(CC1)C(=O)c1ccc(F)cc1)c2=O InChI=1S/C22H22FN3O4/c23-16-3-1-14(2-4-16)20(28)15-7-9-25(10-8-15)11-12-26-21(29)18-6-5-17(27)13-19(18)24-22(26)30/h1-6,13,15,27H,7-12H2,(H,24,30) KUQJDAMRVKQSPB-UHFFFAOYSA-N 50025124 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-7-hydroxy-1H-quinazoline-2,4-dione::CHEMBL46683 D(2) dopamine receptor Rattus norvegicus 164 ChEMBL 10.1021/jm00159a017 10.7270/Q2RX9B3N 3746815 Wouters, W; Janssen, CG; Van Dun, J; Thijssen, JB; Laduron, PM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025124&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290349 103935070 CHEMBL46683 ZINC29401908 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50036451 CCCN1CCCC2C1CCc1c(OS(=O)(=O)C(F)(F)F)cccc21 InChI=1S/C17H22F3NO3S/c1-2-10-21-11-4-6-13-12-5-3-7-16(14(12)8-9-15(13)21)24-25(22,23)17(18,19)20/h3,5,7,13,15H,2,4,6,8-11H2,1H3 NSTMABOREYEUNT-UHFFFAOYSA-N 50039746 CHEMBL327263::Trifluoro-methanesulfonic acid 4-propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-yl ester D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039746&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325658 103946941 CHEMBL327263 ZINC36187794 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50037592 O=C(N[C@H]1CC[C@H]2C[C@H](CC[C@@H]2C1)N1CCN(CC1)c1ccccn1)c1ccccc1 InChI=1S/C26H34N4O/c31-26(20-6-2-1-3-7-20)28-23-11-9-22-19-24(12-10-21(22)18-23)29-14-16-30(17-15-29)25-8-4-5-13-27-25/h1-8,13,21-24H,9-12,14-19H2,(H,28,31)/t21-,22+,23+,24+/m1/s1 OVQXIVRARLGKOO-SBFWRKJZSA-N 50453480 CHEMBL2112745 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm00050a022 10.7270/Q2SN09KN 7990124 Wustrow, DJ; Wise, LD; Cody, DM; MacKenzie, RG; Georgic, LM; Pugsley, TA; Heffner, TG Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453480&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025039 225145950 CHEMBL2112745 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50038893 COc1ccc(CCN2CCN(CC2)c2cccccc2=O)cc1OC InChI=1S/C21H26N2O3/c1-25-20-9-8-17(16-21(20)26-2)10-11-22-12-14-23(15-13-22)18-6-4-3-5-7-19(18)24/h3-9,16H,10-15H2,1-2H3 ZOUKETXVKOUUDH-UHFFFAOYSA-N 50026171 2-[4-(2-Hydroxy-2-phenyl-ethyl)-piperazin-1-yl]-cyclohepta-2,4,6-trienone::CHEMBL418478 D(2) dopamine receptor Rattus norvegicus 880.0 ChEMBL 10.1021/jm00152a004 10.7270/Q2N29VZH 3950903 Bagli, J; Bogri, T; Voith, K; Lee, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15592113 103935905 CHEMBL418478 ZINC29563181 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50038899 Oc1ccc(CCN2CCN(CC2)c2cccccc2=O)cc1O InChI=1S/C19H22N2O3/c22-17-5-3-1-2-4-16(17)21-12-10-20(11-13-21)9-8-15-6-7-18(23)19(24)14-15/h1-7,14,23-24H,8-13H2 UUGUECZFUSLDFG-UHFFFAOYSA-N 50026173 2-{4-[2-(3,4-Dimethoxy-phenyl)-2-hydroxy-ethyl]-piperazin-1-yl}-cyclohepta-2,4,6-trienone::CHEMBL293585 D(2) dopamine receptor Rattus norvegicus 760 ChEMBL 10.1021/jm00152a004 10.7270/Q2N29VZH 3950903 Bagli, J; Bogri, T; Voith, K; Lee, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15592114 103935907 CHEMBL293585 ZINC29561217 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50038902 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm00152a004 10.7270/Q2N29VZH 3950903 Bagli, J; Bogri, T; Voith, K; Lee, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043431 CNc1cc(OC)c(cc1Cl)C(=O)NC1CCN(Cc2ccccc2)C1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26) KRVOJOCLBAAKSJ-UHFFFAOYSA-N 50454212 CHEBI:64217::Emonapride::Nemonapride D(2) dopamine receptor Rattus norvegicus 0.480000 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454212&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search AQD 5WIV,5WIU 4452 225146185 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50042457 COC(=O)C1=C(C)NC(C)=C([C@H]1c1cccc(c1)[N+]([O-])=O)C(=O)OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1 InChI=1S/C36H39N3O6/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24,33,37H,11,18-23H2,1-3H3/t33-/m0/s1 SVJMLYUFVDMUHP-XIFFEERXSA-N 50453799 Niguldipine D(2) dopamine receptor Rattus norvegicus 295 ChEMBL 10.1021/jm960069a 10.7270/Q22Z14NF 8667368 Quaglia, W; Pigini, M; Tayebati, SK; Piergentili, A; Giannella, M; Leonardi, A; Taddei, C; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60602 225146125 C11236 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044750 COc1ccc2CCCC(CCCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C24H32N2O/c1-27-23-13-12-21-8-5-7-20(24(21)19-23)9-6-14-25-15-17-26(18-16-25)22-10-3-2-4-11-22/h2-4,10-13,19-20H,5-9,14-18H2,1H3 VEQQYRMROCWKNF-UHFFFAOYSA-N 50033854 1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL172601 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406491 103942102 CHEMBL172601 ZINC13740692 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50042612 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50042614 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 138 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043862 CN1CCN(CC1(C)C)C1CC(c2cccc(F)c12)c1ccc(F)cc1 InChI=1S/C22H26F2N2/c1-22(2)14-26(12-11-25(22)3)20-13-18(15-7-9-16(23)10-8-15)17-5-4-6-19(24)21(17)20/h4-10,18,20H,11-14H2,1-3H3 BEBKQEVGPRNSGI-UHFFFAOYSA-N 50029368 4-[7-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL137536 D(2) dopamine receptor Rattus norvegicus 74 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029368&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10570260 103938438 CHEMBL137536 ZINC36237970 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043869 N[C@@H]1Cc2ccc(O)cc2[C@H]1c1ccccc1 InChI=1S/C15H15NO/c16-14-8-11-6-7-12(17)9-13(11)15(14)10-4-2-1-3-5-10/h1-7,9,14-15,17H,8,16H2/t14-,15-/m1/s1 FLDPVLFJZMQUDO-HUUCEWRRSA-N 50054089 (2R,3R)-2-Amino-3-phenyl-indan-5-ol::CHEMBL135224 D(2) dopamine receptor Rattus norvegicus 0.59 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054089&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10537185 103950747 CHEMBL135224 ZINC12355919 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043870 CN(CC=C)[C@@H]1Cc2ccc(O)cc2[C@H]1c1ccccc1 InChI=1S/C19H21NO/c1-3-11-20(2)18-12-15-9-10-16(21)13-17(15)19(18)14-7-5-4-6-8-14/h3-10,13,18-19,21H,1,11-12H2,2H3/t18-,19-/m1/s1 XWQIFHFKVSCKAY-RTBURBONSA-N 50054084 (2R,3R)-2-(Allyl-methyl-amino)-3-phenyl-indan-5-ol::CHEMBL135197 D(2) dopamine receptor Rattus norvegicus 0.43 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054084&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10516818 103950742 CHEMBL135197 ZINC27425059 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043871 CN1CCN(CC1)C1CC(c2ccc(F)cc12)c1ccc(F)cc1 InChI=1S/C20H22F2N2/c1-23-8-10-24(11-9-23)20-13-18(14-2-4-15(21)5-3-14)17-7-6-16(22)12-19(17)20/h2-7,12,18,20H,8-11,13H2,1H3 BOFPIRRSGDHUCZ-UHFFFAOYSA-N 50020240 1-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-4-methyl-piperazine::CHEMBL1204285::CHEMBL307717 D(2) dopamine receptor Rattus norvegicus 410 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154762 103931154 CHEMBL307717CHEMBL1204285 ZINC22937739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043872 CN1CCN(CC1)C1CC(c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C21H22F4N2/c1-26-8-10-27(11-9-26)20-13-18(14-2-5-16(22)6-3-14)17-7-4-15(12-19(17)20)21(23,24)25/h2-7,12,18,20H,8-11,13H2,1H3 RVTSEJPJOSUHFO-UHFFFAOYSA-N 50029373 1-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-4-methyl-piperazine::CHEMBL137430 D(2) dopamine receptor Rattus norvegicus 8.1 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029373&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358170 103938443 CHEMBL137430 ZINC22937848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043873 CCCN(CCC)[C@@H]1Cc2ccc(O)cc2[C@H]1c1ccccc1 InChI=1S/C21H27NO/c1-3-12-22(13-4-2)20-14-17-10-11-18(23)15-19(17)21(20)16-8-6-5-7-9-16/h5-11,15,20-21,23H,3-4,12-14H2,1-2H3/t20-,21-/m1/s1 BVGDNYUHGIMUDM-NHCUHLMSSA-N 50054091 (2R,3R)-2-Dipropylamino-3-phenyl-indan-5-ol::CHEMBL335515 D(2) dopamine receptor Rattus norvegicus 0.84 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054091&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10566865 103950749 CHEMBL335515 ZINC27425056 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043876 CN(CC=C)[C@@H]1Cc2cc(O)ccc2[C@H]1c1ccccc1 InChI=1S/C19H21NO/c1-3-11-20(2)18-13-15-12-16(21)9-10-17(15)19(18)14-7-5-4-6-8-14/h3-10,12,18-19,21H,1,11,13H2,2H3/t18-,19-/m1/s1 IFINZBGVEALRFP-RTBURBONSA-N 50054086 (1R,2R)-2-(Allyl-methyl-amino)-1-phenyl-indan-5-ol::CHEMBL134991 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054086&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10540651 103950744 CHEMBL134991 ZINC27420806 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043877 CCC1(CC)CN(CCN1C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C24H30ClFN2/c1-4-24(5-2)16-28(13-12-27(24)3)23-15-21(17-6-9-19(26)10-7-17)20-11-8-18(25)14-22(20)23/h6-11,14,21,23H,4-5,12-13,15-16H2,1-3H3 SWKUTDHWEYGQHY-UHFFFAOYSA-N 50029376 4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-2,2-diethyl-1-methyl-piperazine::CHEMBL137805 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029376&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10787201 103938446 CHEMBL137805 ZINC36093069 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043879 N[C@@H]1Cc2cc(O)ccc2[C@H]1c1ccccc1 InChI=1S/C15H15NO/c16-14-9-11-8-12(17)6-7-13(11)15(14)10-4-2-1-3-5-10/h1-8,14-15,17H,9,16H2/t14-,15-/m1/s1 FSUHLVITEOOXIA-HUUCEWRRSA-N 50054085 (1R,2R)-2-Amino-1-phenyl-indan-5-ol::CHEMBL336366 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054085&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10656804 103950743 CHEMBL336366 ZINC27427375 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043883 CCCN(CCC)[C@@H]1Cc2cc(O)ccc2[C@H]1c1ccccc1 InChI=1S/C21H27NO/c1-3-12-22(13-4-2)20-15-17-14-18(23)10-11-19(17)21(20)16-8-6-5-7-9-16/h5-11,14,20-21,23H,3-4,12-13,15H2,1-2H3/t20-,21-/m1/s1 UKBSEXXIPDXGCH-NHCUHLMSSA-N 50054090 (1R,2R)-2-Dipropylamino-1-phenyl-indan-5-ol::CHEMBL135735 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054090&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10638646 103950748 CHEMBL135735 ZINC27420078 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043889 CC1(C)CN(CCN1CCO)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C23H28ClFN2O/c1-23(2)15-26(9-10-27(23)11-12-28)22-14-20(16-3-6-18(25)7-4-16)19-8-5-17(24)13-21(19)22/h3-8,13,20,22,28H,9-12,14-15H2,1-2H3 UNEFAEQTOYZREV-UHFFFAOYSA-N 50029384 2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-2,2-dimethyl-piperazin-1-yl}-ethanol::CHEMBL136340 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029384&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10787324 103938454 CHEMBL136340 ZINC36093076 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043890 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 330 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043891 CCCN(C)[C@@H]1Cc2cc(O)ccc2[C@H]1c1ccccc1 InChI=1S/C19H23NO/c1-3-11-20(2)18-13-15-12-16(21)9-10-17(15)19(18)14-7-5-4-6-8-14/h4-10,12,18-19,21H,3,11,13H2,1-2H3/t18-,19-/m1/s1 NVTZFGIFPDGDLF-RTBURBONSA-N 50054092 (1R,2R)-2-(Methyl-propyl-amino)-1-phenyl-indan-5-ol::CHEMBL135414 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10564785 103950750 CHEMBL135414 ZINC27419190 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043892 CN1CCN(CC1(C)C)C1CC(c2ccccc12)c1ccc(F)cc1 InChI=1S/C22H27FN2/c1-22(2)15-25(13-12-24(22)3)21-14-20(16-8-10-17(23)11-9-16)18-6-4-5-7-19(18)21/h4-11,20-21H,12-15H2,1-3H3 XUGAKTCCCDRKAF-UHFFFAOYSA-N 50029374 4-[3-(4-Fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136722 D(2) dopamine receptor Rattus norvegicus 29.0 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10246528 103938444 CHEMBL136722 ZINC36237972 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043898 OCCN1CCN(CC11CCCC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C25H30ClFN2O/c26-19-5-8-21-22(18-3-6-20(27)7-4-18)16-24(23(21)15-19)28-11-12-29(13-14-30)25(17-28)9-1-2-10-25/h3-8,15,22,24,30H,1-2,9-14,16-17H2 QIFYCDNAYDWBME-UHFFFAOYSA-N 50029383 2-{9-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-6,9-diaza-spiro[4.5]dec-6-yl}-ethanol::CHEMBL136822 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574585 103938453 CHEMBL136822 ZINC36093082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043899 CCCN(C)[C@@H]1Cc2cc(O)ccc2[C@H]1c1ccccc1 InChI=1S/C19H23NO/c1-3-11-20(2)18-13-15-12-16(21)9-10-17(15)19(18)14-7-5-4-6-8-14/h4-10,12,18-19,21H,3,11,13H2,1-2H3/t18-,19-/m1/s1 NVTZFGIFPDGDLF-RTBURBONSA-N 50054092 (1R,2R)-2-(Methyl-propyl-amino)-1-phenyl-indan-5-ol::CHEMBL135414 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10564785 103950750 CHEMBL135414 ZINC27419190 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043900 Cc1ccc2C(CC(N3CCNC(C)(C)C3)c2c1)c1ccc(F)cc1 InChI=1S/C22H27FN2/c1-15-4-9-18-19(16-5-7-17(23)8-6-16)13-21(20(18)12-15)25-11-10-24-22(2,3)14-25/h4-9,12,19,21,24H,10-11,13-14H2,1-3H3 YGBDHZJMOPGGDK-UHFFFAOYSA-N 50029386 1-[3-(4-Fluoro-phenyl)-6-methyl-indan-1-yl]-3,3-dimethyl-piperazine::CHEMBL140032 D(2) dopamine receptor Rattus norvegicus 5.6 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029386&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10617001 103938456 CHEMBL140032 ZINC22938058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043902 CC(C)N1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C24H30ClFN2/c1-16(2)28-12-11-27(15-24(28,3)4)23-14-21(17-5-8-19(26)9-6-17)20-10-7-18(25)13-22(20)23/h5-10,13,16,21,23H,11-12,14-15H2,1-4H3 FDUMSXVQMHLSOY-UHFFFAOYSA-N 50029375 4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1-isopropyl-2,2-dimethyl-piperazine::CHEMBL136260 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029375&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795296 103938445 CHEMBL136260 ZINC36093075 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043904 OCCN1CCN(CC1)C1CC(c2ccccc12)c1ccccc1 InChI=1S/C21H26N2O/c24-15-14-22-10-12-23(13-11-22)21-16-20(17-6-2-1-3-7-17)18-8-4-5-9-19(18)21/h1-9,20-21,24H,10-16H2 UAAUMFKLNOFEDU-UHFFFAOYSA-N 50029388 2-[4-(3-Phenyl-indan-1-yl)-piperazin-1-yl]-ethanol::CHEMBL136333 D(2) dopamine receptor Rattus norvegicus 2800 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029388&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15115475 103938458 CHEMBL136333 ZINC22937724 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043906 CN1CCN(CC1(C)C)C1CC(c2ccsc2)c2ccc(Cl)cc12 InChI=1S/C20H25ClN2S/c1-20(2)13-23(8-7-22(20)3)19-11-17(14-6-9-24-12-14)16-5-4-15(21)10-18(16)19/h4-6,9-10,12,17,19H,7-8,11,13H2,1-3H3 JUUYXOLEDYTRCB-UHFFFAOYSA-N 50029387 4-(6-Chloro-3-thiophen-3-yl-indan-1-yl)-1,2,2-trimethyl-piperazine::CHEMBL136226 D(2) dopamine receptor Rattus norvegicus 6.1 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029387&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10784787 103938457 CHEMBL136226 ZINC34801000 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043915 OCCN1CCN(CC1)C1CC(c2ccc(F)cc12)c1ccc(F)cc1 InChI=1S/C21H24F2N2O/c22-16-3-1-15(2-4-16)19-14-21(20-13-17(23)5-6-18(19)20)25-9-7-24(8-10-25)11-12-26/h1-6,13,19,21,26H,7-12,14H2 KHGDILJGZLKKBP-UHFFFAOYSA-N 50026951 (cis) 2-{4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL1204347::CHEMBL136562 D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026951&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10320519 103936535 CHEMBL136562CHEMBL1204347 ZINC22937753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043918 CN1CCN(CC1(C)C)C1CC(c2ccc(C)cc12)c1ccc(F)cc1 InChI=1S/C23H29FN2/c1-16-5-10-19-20(17-6-8-18(24)9-7-17)14-22(21(19)13-16)26-12-11-25(4)23(2,3)15-26/h5-10,13,20,22H,11-12,14-15H2,1-4H3 QMRDYJDBHVLYNI-UHFFFAOYSA-N 50029393 4-[3-(4-Fluoro-phenyl)-6-methyl-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL140189 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10641744 103938463 CHEMBL140189 ZINC36238041 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043920 Fc1ccc(cc1)C1CC(N2CCN3CCCCC3C2)c2cc(Cl)ccc12 InChI=1S/C23H26ClFN2/c24-17-6-9-20-21(16-4-7-18(25)8-5-16)14-23(22(20)13-17)27-12-11-26-10-2-1-3-19(26)15-27/h4-9,13,19,21,23H,1-3,10-12,14-15H2 GKDSUAQEAHBUGZ-UHFFFAOYSA-N 50029394 2-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-octahydro-pyrido[1,2-a]pyrazine::CHEMBL335155 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029394&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10810109 103938464 CHEMBL335155 ZINC22937948 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043922 OCCN1CCN(CC1)C1CC(c2c1cccc2Cl)c1ccc(F)cc1 InChI=1S/C21H24ClFN2O/c22-19-3-1-2-17-20(25-10-8-24(9-11-25)12-13-26)14-18(21(17)19)15-4-6-16(23)7-5-15/h1-7,18,20,26H,8-14H2 ADWYWJGQPNBBNY-UHFFFAOYSA-N 50029391 2-{4-[4-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL92896 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029391&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653098 103938461 CHEMBL92896 ZINC22937793 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043924 COc1ccc2C(CC(N3CCN(CCO)CC3)c2c1)c1ccc(F)cc1 InChI=1S/C22H27FN2O2/c1-27-18-6-7-19-20(16-2-4-17(23)5-3-16)15-22(21(19)14-18)25-10-8-24(9-11-25)12-13-26/h2-7,14,20,22,26H,8-13,15H2,1H3 WCIMNWWUWRWLBO-UHFFFAOYSA-N 50029399 2-{4-[3-(4-Fluoro-phenyl)-6-methoxy-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL136841 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029399&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154801 103938469 CHEMBL136841 ZINC22937909 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043930 CN1CCN(CC11CCCC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C24H28ClFN2/c1-27-12-13-28(16-24(27)10-2-3-11-24)23-15-21(17-4-7-19(26)8-5-17)20-9-6-18(25)14-22(20)23/h4-9,14,21,23H,2-3,10-13,15-16H2,1H3 XPYXUCFHJJCHDH-UHFFFAOYSA-N 50029382 9-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-6-methyl-6,9-diaza-spiro[4.5]decane::CHEMBL343922 D(2) dopamine receptor Rattus norvegicus 20.0 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10810927 103938452 CHEMBL343922 ZINC34495818 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043932 CN1CCN(CC1(C)C)C1CC(c2c1cccc2Cl)c1ccc(F)cc1 InChI=1S/C22H26ClFN2/c1-22(2)14-26(12-11-25(22)3)20-13-18(15-7-9-16(24)10-8-15)21-17(20)5-4-6-19(21)23/h4-10,18,20H,11-14H2,1-3H3 NXUBPNABLKWHGY-UHFFFAOYSA-N 50029397 4-[4-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL138964 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9864292 103938467 CHEMBL138964 ZINC36238035 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043936 C[C@H]1N(C)CCc2cc(Cl)c(O)cc2[C@@]1(C)c1ccccc1 InChI=1S/C19H22ClNO/c1-13-19(2,15-7-5-4-6-8-15)16-12-18(22)17(20)11-14(16)9-10-21(13)3/h4-8,11-13,22H,9-10H2,1-3H3/t13-,19-/m1/s1 SQJIIXSSALZMDR-BFUOFWGJSA-N 50029385 (4R,5R)-8-Chloro-3,4,5-trimethyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL136190 D(2) dopamine receptor Rattus norvegicus 3200 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029385&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358126 103938455 CHEMBL136190 ZINC27442206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043939 CN1CCN(CC1(C)C)C1CC(c2ccccc12)c1ccccc1 InChI=1S/C22H28N2/c1-22(2)16-24(14-13-23(22)3)21-15-20(17-9-5-4-6-10-17)18-11-7-8-12-19(18)21/h4-12,20-21H,13-16H2,1-3H3 USXYBVUAZCVLAV-UHFFFAOYSA-N 50029380 1,2,2-Trimethyl-4-(3-phenyl-indan-1-yl)-piperazine::CHEMBL344680 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10567738 103938450 CHEMBL344680 ZINC36238021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043940 CN1CCN(CC11CCC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C23H26ClFN2/c1-26-11-12-27(15-23(26)9-2-10-23)22-14-20(16-3-6-18(25)7-4-16)19-8-5-17(24)13-21(19)22/h3-8,13,20,22H,2,9-12,14-15H2,1H3 DSKGHESLQPEDPR-UHFFFAOYSA-N 50029395 8-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-5-methyl-5,8-diaza-spiro[3.5]nonane::CHEMBL344206 D(2) dopamine receptor Rattus norvegicus 6.3 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11794473 103938465 CHEMBL344206 ZINC36093068 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043942 CC1(C)CN(CCN1)C1CC(c2ccsc2)c2ccc(Cl)cc12 InChI=1S/C19H23ClN2S/c1-19(2)12-22(7-6-21-19)18-10-16(13-5-8-23-11-13)15-4-3-14(20)9-17(15)18/h3-5,8-9,11,16,18,21H,6-7,10,12H2,1-2H3 YSCQLSNJEINTEZ-UHFFFAOYSA-N 50029377 1-(6-Chloro-3-thiophen-3-yl-indan-1-yl)-3,3-dimethyl-piperazine::CHEMBL343282 D(2) dopamine receptor Rattus norvegicus 8.20 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10712649 103938447 CHEMBL343282 ZINC34800998 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043946 CN1CCN(CC11CCCCC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C25H30ClFN2/c1-28-13-14-29(17-25(28)11-3-2-4-12-25)24-16-22(18-5-8-20(27)9-6-18)21-10-7-19(26)15-23(21)24/h5-10,15,22,24H,2-4,11-14,16-17H2,1H3 KDDUICUDCSCLSK-UHFFFAOYSA-N 50029379 4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1-methyl-1,4-diaza-spiro[5.5]undecane::CHEMBL344426 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029379&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10693049 103938449 CHEMBL344426 ZINC36093083 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043948 CC(C)c1ccc2C(CC(N3CCN(CCO)CC3)c2c1)c1ccc(F)cc1 InChI=1S/C24H31FN2O/c1-17(2)19-5-8-21-22(18-3-6-20(25)7-4-18)16-24(23(21)15-19)27-11-9-26(10-12-27)13-14-28/h3-8,15,17,22,24,28H,9-14,16H2,1-2H3 LUZRJLPCCNZOME-UHFFFAOYSA-N 50029404 2-{4-[3-(4-Fluoro-phenyl)-6-isopropyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL136262 D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029404&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154798 103938474 CHEMBL136262 ZINC22937897 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043949 CC1(C)CN(CCN1CCCO)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C24H30ClFN2O/c1-24(2)16-27(11-12-28(24)10-3-13-29)23-15-21(17-4-7-19(26)8-5-17)20-9-6-18(25)14-22(20)23/h4-9,14,21,23,29H,3,10-13,15-16H2,1-2H3 LYDWOPLSIWWSOT-UHFFFAOYSA-N 50029400 3-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-2,2-dimethyl-piperazin-1-yl}-propan-1-ol::CHEMBL136932 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029400&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10525990 103938470 CHEMBL136932 ZINC36093070 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043950 CSc1ccc2C(CC(N3CCN(CCO)CC3)c2c1)c1ccc(F)cc1 InChI=1S/C22H27FN2OS/c1-27-18-6-7-19-20(16-2-4-17(23)5-3-16)15-22(21(19)14-18)25-10-8-24(9-11-25)12-13-26/h2-7,14,20,22,26H,8-13,15H2,1H3 CZQKXAJZKVTBEV-UHFFFAOYSA-N 50029403 2-{4-[3-(4-Fluoro-phenyl)-6-methylsulfanyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL337542 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029403&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154803 103938473 CHEMBL337542 ZINC22937923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043951 CN1CCN(CC1(C)C)C1CC(c2cc(Cl)ccc12)c1ccc(F)cc1 InChI=1S/C22H26ClFN2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-7-17(24)8-5-15)20-12-16(23)6-9-18(20)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3 KMKBRLPCUKJMSX-UHFFFAOYSA-N 50029381 4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136891 D(2) dopamine receptor Rattus norvegicus 340 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029381&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10619325 103938451 CHEMBL136891 ZINC34800997 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043958 OCCN1CCN(CC1)C1CC(c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2 JSBWGXQXCRYYTG-UHFFFAOYSA-N 50002012 (trans) 2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL1204138::CHEMBL12628::tefludazine D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002012&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4913274 103916365 CHEMBL12628CHEMBL1204138 ZINC22937858 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043959 CN1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C22H26ClFN2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-7-17(24)8-5-15)18-9-6-16(23)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3 PUQPKVFFZKBJLD-UHFFFAOYSA-N 50029378 4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136630 D(2) dopamine receptor Rattus norvegicus 5.00 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809333 103938448 CHEMBL136630 ZINC34800999 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043961 OCCN1CCN(CC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2O/c22-16-3-6-18-19(15-1-4-17(23)5-2-15)14-21(20(18)13-16)25-9-7-24(8-10-25)11-12-26/h1-6,13,19,21,26H,7-12,14H2 WVMPJMHWCBRDFH-UHFFFAOYSA-N 50026960 (trans) 2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol; Dihydrochloride::2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL422067 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10478809 103936544 CHEMBL422067 ZINC22937822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043962 CC1CN(CCN1C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2/c1-14-13-25(10-9-24(14)2)21-12-19(15-3-6-17(23)7-4-15)18-8-5-16(22)11-20(18)21/h3-8,11,14,19,21H,9-10,12-13H2,1-2H3 NDIIKLHONTYYRL-UHFFFAOYSA-N 50029392 4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2-dimethyl-piperazine::CHEMBL344216 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029392&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10666149 103938462 CHEMBL344216 ZINC36093072 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043972 CN1CCN(CC1)C1CC(c2ccccc12)c1ccccc1 InChI=1S/C20H24N2/c1-21-11-13-22(14-12-21)20-15-19(16-7-3-2-4-8-16)17-9-5-6-10-18(17)20/h2-10,19-20H,11-15H2,1H3 PBNIVFQAAKTXAH-UHFFFAOYSA-N 50029406 1-Methyl-4-(3-phenyl-indan-1-yl)-piperazine::CHEMBL343820 D(2) dopamine receptor Rattus norvegicus 690 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029406&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358098 103938476 CHEMBL343820 ZINC22778646 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043978 CN1CCN(CC1(C)C)C1CC(c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C23H26F4N2/c1-22(2)14-29(11-10-28(22)3)21-13-19(15-4-7-17(24)8-5-15)18-9-6-16(12-20(18)21)23(25,26)27/h4-9,12,19,21H,10-11,13-14H2,1-3H3 FOLDFBZXQLCLJB-UHFFFAOYSA-N 50029408 4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL343078 D(2) dopamine receptor Rattus norvegicus 5.7 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029408&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10835172 103938478 CHEMBL343078 ZINC36238044 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043982 CN1CCN(CC1)C1CC(c2ccc(Cl)cc12)c1ccccc1 InChI=1S/C20H23ClN2/c1-22-9-11-23(12-10-22)20-14-18(15-5-3-2-4-6-15)17-8-7-16(21)13-19(17)20/h2-8,13,18,20H,9-12,14H2,1H3 OUTQVQKOJHLKNN-UHFFFAOYSA-N 50029372 1-(6-Chloro-3-phenyl-indan-1-yl)-4-methyl-piperazine::CHEMBL136553 D(2) dopamine receptor Rattus norvegicus 61 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029372&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15115476 103938442 CHEMBL136553 ZINC22937765 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043985 CS(=O)(=O)c1ccc2C(CC(N3CCN(CCO)CC3)c2c1)c1ccc(F)cc1 InChI=1S/C22H27FN2O3S/c1-29(27,28)18-6-7-19-20(16-2-4-17(23)5-3-16)15-22(21(19)14-18)25-10-8-24(9-11-25)12-13-26/h2-7,14,20,22,26H,8-13,15H2,1H3 DGEMRQOHHQEUDR-UHFFFAOYSA-N 50029411 2-{4-[3-(4-Fluoro-phenyl)-6-methanesulfonyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL139304 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029411&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154822 103938481 CHEMBL139304 ZINC22937936 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043986 CN1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccc(Cl)cc1 InChI=1S/C22H26Cl2N2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-6-16(23)7-5-15)18-9-8-17(24)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3 RKDGTQHEOBQEAS-UHFFFAOYSA-N 50029401 4-[6-Chloro-3-(4-chloro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL139258 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029401&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10548369 103938471 CHEMBL139258 ZINC36238046 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043990 Cc1ccc2C(CC(N3CCN(CCO)CC3)c2c1)c1ccc(F)cc1 InChI=1S/C22H27FN2O/c1-16-2-7-19-20(17-3-5-18(23)6-4-17)15-22(21(19)14-16)25-10-8-24(9-11-25)12-13-26/h2-7,14,20,22,26H,8-13,15H2,1H3 PIFJXKYJXNZXRB-UHFFFAOYSA-N 50026962 2-{4-[3-(4-Fluoro-phenyl)-6-methyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL137954 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026962&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154795 103936546 CHEMBL137954 ZINC22937884 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043996 CN1CCN(CC1(C)C)C1CC(c2cccc(Cl)c12)c1ccc(F)cc1 InChI=1S/C22H26ClFN2/c1-22(2)14-26(12-11-25(22)3)20-13-18(15-7-9-16(24)10-8-15)17-5-4-6-19(23)21(17)20/h4-10,18,20H,11-14H2,1-3H3 CRLRIFICOHQHTR-UHFFFAOYSA-N 50029398 4-[7-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136334 D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809334 103938468 CHEMBL136334 ZINC36238027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044006 CN1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1cccc(F)c1 InChI=1S/C22H26ClFN2/c1-22(2)14-26(10-9-25(22)3)21-13-19(15-5-4-6-17(24)11-15)18-8-7-16(23)12-20(18)21/h4-8,11-12,19,21H,9-10,13-14H2,1-3H3 OVWCWUCMWSYGNV-UHFFFAOYSA-N 50029407 4-[6-Chloro-3-(3-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136873 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029407&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10833129 103938477 CHEMBL136873 ZINC36238029 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044019 CC1(C)CN(CCN1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2/c1-21(2)13-25(10-9-24-21)20-12-18(14-3-6-16(23)7-4-14)17-8-5-15(22)11-19(17)20/h3-8,11,18,20,24H,9-10,12-13H2,1-2H3 YBDPFVPDVAAUOC-UHFFFAOYSA-N 50029371 1-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-3,3-dimethyl-piperazine::CHEMBL136683 D(2) dopamine receptor Rattus norvegicus 12000 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029371&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10043978 103938441 CHEMBL136683 ZINC34136407 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044021 OCCN1CCN(CC1)C1CC(c2cc(Cl)ccc12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2O/c22-16-3-6-18-20(13-16)19(15-1-4-17(23)5-2-15)14-21(18)25-9-7-24(8-10-25)11-12-26/h1-6,13,19,21,26H,7-12,14H2 ZTECBXOHIVSPQL-UHFFFAOYSA-N 50029412 (+)-2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol dihydrochloride::(-)-2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol dihydrochloride::2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol dihydrochloride::CHEMBL92560 D(2) dopamine receptor Rattus norvegicus 2200 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029412&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653097 103938482 CHEMBL92560 ZINC22937810 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044024 CC1CN(CC(C)N1C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C22H26ClFN2/c1-14-12-26(13-15(2)25(14)3)22-11-20(16-4-7-18(24)8-5-16)19-9-6-17(23)10-21(19)22/h4-10,14-15,20,22H,11-13H2,1-3H3 JQBCJANIMSRFBC-UHFFFAOYSA-N 50029396 4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,6-trimethyl-piperazine::CHEMBL138745 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029396&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10523361 103938466 CHEMBL138745 ZINC36093086 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044025 CN1CCN(CC1)C1CC(c2ccc(C)cc12)c1ccc(F)cc1 InChI=1S/C21H25FN2/c1-15-3-8-18-19(16-4-6-17(22)7-5-16)14-21(20(18)13-15)24-11-9-23(2)10-12-24/h3-8,13,19,21H,9-12,14H2,1-2H3 ZLENAKCUDMRTST-UHFFFAOYSA-N 50029410 1-[3-(4-Fluoro-phenyl)-6-methyl-indan-1-yl]-4-methyl-piperazine::CHEMBL136480 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029410&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358128 103938480 CHEMBL136480 ZINC27440465 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044030 CN1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccccc1F InChI=1S/C22H26ClFN2/c1-22(2)14-26(11-10-25(22)3)21-13-18(17-6-4-5-7-20(17)24)16-9-8-15(23)12-19(16)21/h4-9,12,18,21H,10-11,13-14H2,1-3H3 BEJFETGIBLFMPS-UHFFFAOYSA-N 50029405 4-[6-Chloro-3-(2-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136468 D(2) dopamine receptor Rattus norvegicus 36 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029405&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809335 103938475 CHEMBL136468 ZINC36238025 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044033 OCCN1CCN(CC1)C1CC(c2cccc(Cl)c12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2O/c22-19-3-1-2-17-18(15-4-6-16(23)7-5-15)14-20(21(17)19)25-10-8-24(9-11-25)12-13-26/h1-7,18,20,26H,8-14H2 HKWOIXRWXXYROZ-UHFFFAOYSA-N 50029402 2-{4-[7-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[7-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol dimaleate::CHEMBL1788129::CHEMBL96618 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029402&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653096 103938472 CHEMBL1788129CHEMBL96618 ZINC22937835 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044038 CC1CN(C2CC(c3ccc(Cl)cc23)c2ccc(F)cc2)C(C)CN1C InChI=1S/C22H26ClFN2/c1-14-13-26(15(2)12-25(14)3)22-11-20(16-4-7-18(24)8-5-16)19-9-6-17(23)10-21(19)22/h4-10,14-15,20,22H,11-13H2,1-3H3 VPBCZFXEYITWLJ-UHFFFAOYSA-N 50029409 1-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-2,4,5-trimethyl-piperazine::CHEMBL342698 D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029409&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10595484 103938479 CHEMBL342698 ZINC36093074 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044040 CC1(C)CN(CCN1)C1CC(c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2/c1-21(2)13-28(10-9-27-21)20-12-18(14-3-6-16(23)7-4-14)17-8-5-15(11-19(17)20)22(24,25)26/h3-8,11,18,20,27H,9-10,12-13H2,1-2H3 DLAZTOJTTMSVCY-UHFFFAOYSA-N 50029389 1-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-3,3-dimethyl-piperazine::CHEMBL136648 D(2) dopamine receptor Rattus norvegicus 5.2 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029389&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10810514 103938459 CHEMBL136648 ZINC36238033 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044043 CN1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccccc1 InChI=1S/C22H27ClN2/c1-22(2)15-25(12-11-24(22)3)21-14-19(16-7-5-4-6-8-16)18-10-9-17(23)13-20(18)21/h4-10,13,19,21H,11-12,14-15H2,1-3H3 BYPMJBXPNZMNQD-UHFFFAOYSA-N 50029369 4-(6-Chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine::CHEMBL137960 D(2) dopamine receptor Rattus norvegicus 260 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029369&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10247592 103938439 CHEMBL137960 ZINC34800996 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044045 CN1CCN(CC1(C)C)C1CC(c2ccc(Br)cc12)c1ccc(F)cc1 InChI=1S/C22H26BrFN2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-7-17(24)8-5-15)18-9-6-16(23)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3 NAYPPFWCBZMRQV-UHFFFAOYSA-N 50029390 4-[6-Bromo-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136776 D(2) dopamine receptor Rattus norvegicus 8.6 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029390&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10525999 103938460 CHEMBL136776 ZINC36238023 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044050 CN1CCN(CC1(C)C)C1CC(c2ccc(F)cc12)c1ccc(F)cc1 InChI=1S/C22H26F2N2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-6-16(23)7-5-15)18-9-8-17(24)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3 QMXMQVFBAZCMSE-UHFFFAOYSA-N 50029370 4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136235 D(2) dopamine receptor Rattus norvegicus 1500 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029370&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522247 103938440 CHEMBL136235 ZINC36237974 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040898 CN1CCN(CC1)C1CC(c2ccc(F)cc12)c1ccc(F)cc1 InChI=1S/C20H22F2N2/c1-23-8-10-24(11-9-23)20-13-18(14-2-4-15(21)5-3-14)17-7-6-16(22)12-19(17)20/h2-7,12,18,20H,8-11,13H2,1H3 BOFPIRRSGDHUCZ-UHFFFAOYSA-N 50020240 1-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-4-methyl-piperazine::CHEMBL1204285::CHEMBL307717 D(2) dopamine receptor Rattus norvegicus 91.0 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154762 103931154 CHEMBL307717CHEMBL1204285 ZINC22937739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040899 CN1CCN(CC1)C1CC(c2cc(Cl)ccc12)c1ccc(F)cc1 InChI=1S/C20H22ClFN2/c1-23-8-10-24(11-9-23)20-13-18(14-2-5-16(22)6-3-14)19-12-15(21)4-7-17(19)20/h2-7,12,18,20H,8-11,13H2,1H3 DZPXGKJWGJRSKF-UHFFFAOYSA-N 50453947 CHEMBL2111937 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71454427 225146148 CHEMBL2111937 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040900 CC(C)N1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C24H30ClFN2/c1-16(2)28-12-11-27(15-24(28,3)4)23-14-21(17-5-8-19(26)9-6-17)20-10-7-18(25)13-22(20)23/h5-10,13,16,21,23H,11-12,14-15H2,1-4H3 FDUMSXVQMHLSOY-UHFFFAOYSA-N 50029375 4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1-isopropyl-2,2-dimethyl-piperazine::CHEMBL136260 D(2) dopamine receptor Rattus norvegicus 5.0 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029375&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795296 103938445 CHEMBL136260 ZINC36093075 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040901 CC1(C)CN(CCN1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2/c1-21(2)13-25(10-9-24-21)20-12-18(14-3-6-16(23)7-4-14)17-8-5-15(22)11-19(17)20/h3-8,11,18,20,24H,9-10,12-13H2,1-2H3 YBDPFVPDVAAUOC-UHFFFAOYSA-N 50029371 1-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-3,3-dimethyl-piperazine::CHEMBL136683 D(2) dopamine receptor Rattus norvegicus 12000 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029371&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10043978 103938441 CHEMBL136683 ZINC34136407 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040903 CN1CCN(CC1(C)C)C1CC(c2ccccc12)c1ccc(F)cc1 InChI=1S/C22H27FN2/c1-22(2)15-25(13-12-24(22)3)21-14-20(16-8-10-17(23)11-9-16)18-6-4-5-7-19(18)21/h4-11,20-21H,12-15H2,1-3H3 XUGAKTCCCDRKAF-UHFFFAOYSA-N 50029374 4-[3-(4-Fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136722 D(2) dopamine receptor Rattus norvegicus 29.0 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10246528 103938444 CHEMBL136722 ZINC36237972 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040905 CN1CCN(CC1(C)C)C1CC(c2ccc(F)cc12)c1ccc(F)cc1 InChI=1S/C22H26F2N2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-6-16(23)7-5-15)18-9-8-17(24)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3 QMXMQVFBAZCMSE-UHFFFAOYSA-N 50029370 4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136235 D(2) dopamine receptor Rattus norvegicus 1500 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029370&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522247 103938440 CHEMBL136235 ZINC36237974 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040906 CN1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C22H26ClFN2/c1-22(2)14-26(11-10-25(22)3)21-13-19(15-4-7-17(24)8-5-15)18-9-6-16(23)12-20(18)21/h4-9,12,19,21H,10-11,13-14H2,1-3H3 PUQPKVFFZKBJLD-UHFFFAOYSA-N 50029378 4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine::CHEMBL136630 D(2) dopamine receptor Rattus norvegicus 5.0 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809333 103938448 CHEMBL136630 ZINC34800999 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043065 CNc1cc(OC)c(cc1Cl)C(=O)NC1CCN(Cc2ccccc2)C1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26) KRVOJOCLBAAKSJ-UHFFFAOYSA-N 50454212 CHEBI:64217::Emonapride::Nemonapride D(2) dopamine receptor Rattus norvegicus 0.160000 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454212&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search AQD 5WIV,5WIU 4452 225146185 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043129 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccncc1 InChI=1S/C20H20N2/c1-2-7-19(8-3-1)20-11-16-22(17-12-20)15-5-4-6-18-9-13-21-14-10-18/h1-3,7-11,13-14H,5,12,15-17H2 VPUYNZMAEQVXFX-UHFFFAOYSA-N 50052533 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL110489 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052533&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10684789 103949385 CHEMBL110489 ZINC01533847 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043130 Nc1ccc(nc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C20H21N3/c21-19-9-10-20(22-16-19)8-4-5-13-23-14-11-18(12-15-23)17-6-2-1-3-7-17/h1-3,6-7,9-11,16H,5,12-15,21H2 LPLZFZAIOWVRTJ-UHFFFAOYSA-N 50052532 6-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridin-3-ylamine::CHEMBL109101 D(2) dopamine receptor Rattus norvegicus 1.9 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086348 103949384 CHEMBL109101 ZINC01533848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043131 Nc1ccc(cn1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C20H21N3/c21-20-10-9-17(16-22-20)6-4-5-13-23-14-11-19(12-15-23)18-7-2-1-3-8-18/h1-3,7-11,16H,5,12-15H2,(H2,21,22) KAPNJGZVRYPTJW-UHFFFAOYSA-N 50052530 5-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridin-2-ylamine::CHEMBL109063 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357631 103949382 CHEMBL109063 ZINC26941584 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040907 CC1(C)CN(CCN1)C1CC(c2ccsc2)c2ccc(Cl)cc12 InChI=1S/C19H23ClN2S/c1-19(2)12-22(7-6-21-19)18-10-16(13-5-8-23-11-13)15-4-3-14(20)9-17(15)18/h3-5,8-9,11,16,18,21H,6-7,10,12H2,1-2H3 YSCQLSNJEINTEZ-UHFFFAOYSA-N 50029377 1-(6-Chloro-3-thiophen-3-yl-indan-1-yl)-3,3-dimethyl-piperazine::CHEMBL343282 D(2) dopamine receptor Rattus norvegicus 7.1 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10712649 103938447 CHEMBL343282 ZINC34800998 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040909 CN1CCN(CC11CCCC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C24H28ClFN2/c1-27-12-13-28(16-24(27)10-2-3-11-24)23-15-21(17-4-7-19(26)8-5-17)20-9-6-18(25)14-22(20)23/h4-9,14,21,23H,2-3,10-13,15-16H2,1H3 XPYXUCFHJJCHDH-UHFFFAOYSA-N 50029382 9-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-6-methyl-6,9-diaza-spiro[4.5]decane::CHEMBL343922 D(2) dopamine receptor Rattus norvegicus 10.00 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10810927 103938452 CHEMBL343922 ZINC34495818 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040917 OCCN1CCN(CC11CCCC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C25H30ClFN2O/c26-19-5-8-21-22(18-3-6-20(27)7-4-18)16-24(23(21)15-19)28-11-12-29(13-14-30)25(17-28)9-1-2-10-25/h3-8,15,22,24,30H,1-2,9-14,16-17H2 QIFYCDNAYDWBME-UHFFFAOYSA-N 50029383 2-{9-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-6,9-diaza-spiro[4.5]dec-6-yl}-ethanol::CHEMBL136822 D(2) dopamine receptor Rattus norvegicus 5.0 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574585 103938453 CHEMBL136822 ZINC36093082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50040920 CN1CCN(CC1(C)C)C1CC(c2ccc(Cl)cc12)c1ccccc1 InChI=1S/C22H27ClN2/c1-22(2)15-25(12-11-24(22)3)21-14-19(16-7-5-4-6-8-16)18-10-9-17(23)13-20(18)21/h4-10,13,19,21H,11-12,14-15H2,1-3H3 BYPMJBXPNZMNQD-UHFFFAOYSA-N 50029369 4-(6-Chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine::CHEMBL137960 D(2) dopamine receptor Rattus norvegicus 260 ChEMBL 10.1021/jm00022a004 10.7270/Q28C9V87 7473566 Bogeso, KP; Arnt, J; Frederiksen, K; Hansen, HO; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029369&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10247592 103938439 CHEMBL137960 ZINC34800996 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043132 C(CN1CCC(=CC1)c1ccccc1)C#Cc1cccnc1 InChI=1S/C20H20N2/c1-2-9-19(10-3-1)20-11-15-22(16-12-20)14-5-4-7-18-8-6-13-21-17-18/h1-3,6,8-11,13,17H,5,12,14-16H2 QNTNWSQRMBFBSH-UHFFFAOYSA-N 50052528 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL108463 D(2) dopamine receptor Rattus norvegicus 37 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10827222 103949380 CHEMBL108463 ZINC01533844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043133 Nc1ccc(cc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c22-21-11-9-18(10-12-21)6-4-5-15-23-16-13-20(14-17-23)19-7-2-1-3-8-19/h1-3,7-13H,5,14-17,22H2 STFIELBPKGAKNX-UHFFFAOYSA-N 50052531 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL108531 D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425024 103949383 CHEMBL108531 ZINC01533849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50043134 Nc1cccc(c1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c22-21-11-6-8-18(17-21)7-4-5-14-23-15-12-20(13-16-23)19-9-2-1-3-10-19/h1-3,6,8-12,17H,5,13-16,22H2 KHTVRVDYYAMNRK-UHFFFAOYSA-N 50052535 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL108532 D(2) dopamine receptor Rattus norvegicus 87 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052535&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10780717 103949387 CHEMBL108532 ZINC13757298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044251 CCN(CC)CCc1c[nH]c2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C15H19F3N2O3S/c1-3-20(4-2)8-7-11-10-19-14-6-5-12(9-13(11)14)23-24(21,22)15(16,17)18/h5-6,9-10,19H,3-4,7-8H2,1-2H3 RIQXJVJIJZOICG-UHFFFAOYSA-N 50054757 CHEMBL143510::Trifluoro-methanesulfonic acid 3-(2-diethylamino-ethyl)-1H-indol-5-yl ester D(2) dopamine receptor Rattus norvegicus 637 ChEMBL 10.1021/jm9604890 10.7270/Q2R210GS 8941384 Barf, TA; de Boer, P; Wikstrom, H; Peroutka, SJ; Swensson, K; Ennis, MD; Ghazal, NB; McGuire, JC; Smith, MW University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054757&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618751 103951342 CHEMBL143510 ZINC34801067 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044252 NCCc1c[nH]c2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C11H11F3N2O3S/c12-11(13,14)20(17,18)19-8-1-2-10-9(5-8)7(3-4-15)6-16-10/h1-2,5-6,16H,3-4,15H2 GUJBOPKUKWHUKV-UHFFFAOYSA-N 50054762 CHEMBL143512::Trifluoro-methanesulfonic acid 3-(2-amino-ethyl)-1H-indol-5-yl ester D(2) dopamine receptor Rattus norvegicus 658 ChEMBL 10.1021/jm9604890 10.7270/Q2R210GS 8941384 Barf, TA; de Boer, P; Wikstrom, H; Peroutka, SJ; Swensson, K; Ennis, MD; Ghazal, NB; McGuire, JC; Smith, MW University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054762&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10518850 103951347 CHEMBL143512 ZINC34801066 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044253 CN(C)CCc1c[nH]c2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C13H15F3N2O3S/c1-18(2)6-5-9-8-17-12-4-3-10(7-11(9)12)21-22(19,20)13(14,15)16/h3-4,7-8,17H,5-6H2,1-2H3 HWRKZNBGZMBBTP-UHFFFAOYSA-N 50054761 CHEMBL143767::Trifluoro-methanesulfonic acid 3-(2-dimethylamino-ethyl)-1H-indol-5-yl ester D(2) dopamine receptor Rattus norvegicus 538 ChEMBL 10.1021/jm9604890 10.7270/Q2R210GS 8941384 Barf, TA; de Boer, P; Wikstrom, H; Peroutka, SJ; Swensson, K; Ennis, MD; Ghazal, NB; McGuire, JC; Smith, MW University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054761&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9802530 103951346 CHEMBL143767 ZINC14299870 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044255 CCCN(CCC)CCc1c[nH]c2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C17H23F3N2O3S/c1-3-8-22(9-4-2)10-7-13-12-21-16-6-5-14(11-15(13)16)25-26(23,24)17(18,19)20/h5-6,11-12,21H,3-4,7-10H2,1-2H3 WWJQYDAINIQCOK-UHFFFAOYSA-N 50054760 CHEMBL143967::Trifluoro-methanesulfonic acid 3-(2-dipropylamino-ethyl)-1H-indol-5-yl ester D(2) dopamine receptor Rattus norvegicus 502 ChEMBL 10.1021/jm9604890 10.7270/Q2R210GS 8941384 Barf, TA; de Boer, P; Wikstrom, H; Peroutka, SJ; Swensson, K; Ennis, MD; Ghazal, NB; McGuire, JC; Smith, MW University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054760&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10691904 103951345 CHEMBL143967 ZINC34801068 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50044385 CNS(=O)(=O)Cc1ccc2[nH]cc(CCN(C)C)c2c1 InChI=1S/C14H21N3O2S/c1-15-20(18,19)10-11-4-5-14-13(8-11)12(9-16-14)6-7-17(2)3/h4-5,8-9,15-16H,6-7,10H2,1-3H3 KQKPFRSPSRPDEB-UHFFFAOYSA-N 50005835 (3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide::1-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-methyl-methanesulfonamide::1-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}-N-methylmethanesulfonamide::3-(2-(dimethylamino)ethyl)-N-methyl-1H-indole-5-methanesulfonamide::3-[2-(dimethylamino)ethyl]-N-methylindole-5-methanesulfonamide::CHEMBL128::SUMATRIPTAN::Sumatran::Sumax D(2) dopamine receptor Rattus norvegicus >218 ChEMBL 10.1021/jm9604890 10.7270/Q2R210GS 8941384 Barf, TA; de Boer, P; Wikstrom, H; Peroutka, SJ; Swensson, K; Ennis, MD; Ghazal, NB; McGuire, JC; Smith, MW University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5358 103919260 10650 CHEMBL128 DB00669 119 C07319 ZINC00014360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50046689 CCc1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C17H19NO2S/c1-2-10-6-12-16(21-10)8-18-13-4-3-9-5-14(19)15(20)7-11(9)17(12)13/h5-7,13,17-20H,2-4,8H2,1H3/t13-,17+/m0/s1 OXIMNPYYZPJDBV-SUMWQHHRSA-N 50408143 CHEMBL2115377 D(2) dopamine receptor Rattus norvegicus 640 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408143&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10709445 163357167 CHEMBL2115377 ZINC00006166 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50046690 CCCc1cc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C18H21NO2S/c1-2-3-11-7-13-17(22-11)9-19-14-5-4-10-6-15(20)16(21)8-12(10)18(13)14/h6-8,14,18-21H,2-5,9H2,1H3/t14-,18+/m1/s1 REHAKLRYABHSQJ-KDOFPFPSSA-N 50033114 (5aR,11bS)-2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::A-86929::CHEMBL28338 D(2) dopamine receptor Rattus norvegicus 800 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033114&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9841398 103941455 CHEMBL28338 ZINC00019656 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50046691 CC(C)(C)c1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C19H23NO2S/c1-19(2,3)17-8-12-16(23-17)9-20-13-5-4-10-6-14(21)15(22)7-11(10)18(12)13/h6-8,13,18,20-22H,4-5,9H2,1-3H3/t13-,18+/m0/s1 JRQAGZUTSLOUSW-SCLBCKFNSA-N 50408144 CHEMBL2115373 D(2) dopamine receptor Rattus norvegicus 3260 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408144&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10758745 163357168 CHEMBL2115373 ZINC01539971 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50046693 CC(C)(C)c1cc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C19H23NO2S/c1-19(2,3)17-8-12-16(23-17)9-20-13-5-4-10-6-14(21)15(22)7-11(10)18(12)13/h6-8,13,18,20-22H,4-5,9H2,1-3H3/t13-,18+/m1/s1 JRQAGZUTSLOUSW-ACJLOTCBSA-N 50408145 CHEMBL2114441 D(2) dopamine receptor Rattus norvegicus 1380 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408145&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640108 163357169 CHEMBL2114441 ZINC13762051 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50046702 CCCc1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C18H21NO2S/c1-2-3-11-7-13-17(22-11)9-19-14-5-4-10-6-15(20)16(21)8-12(10)18(13)14/h6-8,14,18-21H,2-5,9H2,1H3/t14-,18+/m0/s1 REHAKLRYABHSQJ-KBXCAEBGSA-N 50033115 (5aS,11bR)-2-Propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol; hydrochloride::CHEMBL2115374::CHEMBL544814 D(2) dopamine receptor Rattus norvegicus 5400 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033115&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9796958 103941456 CHEMBL2115374CHEMBL544814 ZINC01539970 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50046703 Cc1cc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C16H17NO2S/c1-8-4-11-15(20-8)7-17-12-3-2-9-5-13(18)14(19)6-10(9)16(11)12/h4-6,12,16-19H,2-3,7H2,1H3/t12-,16+/m1/s1 OHQFGIVFMUFZJP-WBMJQRKESA-N 50408147 CHEMBL2114440 D(2) dopamine receptor Rattus norvegicus 240 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408147&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10732044 163357171 CHEMBL2114440 ZINC13762048 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50046707 Cc1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C16H17NO2S/c1-8-4-11-15(20-8)7-17-12-3-2-9-5-13(18)14(19)6-10(9)16(11)12/h4-6,12,16-19H,2-3,7H2,1H3/t12-,16+/m0/s1 OHQFGIVFMUFZJP-BLLLJJGKSA-N 50408141 CHEMBL2115372 D(2) dopamine receptor Rattus norvegicus 980 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408141&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10684714 163357165 CHEMBL2115372 ZINC00019074 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50046712 CCc1cc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C17H19NO2S/c1-2-10-6-12-16(21-10)8-18-13-4-3-9-5-14(19)15(20)7-11(9)17(12)13/h5-7,13,17-20H,2-4,8H2,1H3/t13-,17+/m1/s1 OXIMNPYYZPJDBV-DYVFJYSZSA-N 50408146 CHEMBL2114444 D(2) dopamine receptor Rattus norvegicus 345 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50408146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50408146&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10662054 163357170 CHEMBL2114444 ZINC13762049 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50047889 NCC(Cc1ccccc1)c1ccc(O)c(O)c1 InChI=1S/C15H17NO2/c16-10-13(8-11-4-2-1-3-5-11)12-6-7-14(17)15(18)9-12/h1-7,9,13,17-18H,8,10,16H2 XHFQGJPSFDFHAT-UHFFFAOYSA-N 50031567 4-(1-Aminomethyl-2-phenyl-ethyl)-benzene-1,2-diol::CHEMBL82706 D(2) dopamine receptor Rattus norvegicus 2500 ChEMBL 10.1021/jm00013a015 10.7270/Q2HM57GJ 7608904 Snyder, SE; Aviles-Garay, FA; Chakraborti, R; Nichols, DE; Watts, VJ; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44317479 103940198 CHEMBL82706 ZINC26488184 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50048409 C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12 InChI=1S/C25H32N4/c1-2-6-24-22(5-1)23(19-27-24)21-10-8-20(9-11-21)12-14-28-15-17-29(18-16-28)25-7-3-4-13-26-25/h1-7,13,19-21,27H,8-12,14-18H2/t20-,21- WKRNNVUISXJKDT-MEMLXQNLSA-N 50055721 3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL423499 D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9886609 103952203 CHEMBL423499 ZINC26575180 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049873 COc1ccc2CCC(CNCCCO)Oc2c1 InChI=1S/C14H21NO3/c1-17-12-5-3-11-4-6-13(18-14(11)9-12)10-15-7-2-8-16/h3,5,9,13,15-16H,2,4,6-8,10H2,1H3 CCFWRAKLQXVCPZ-UHFFFAOYSA-N 50061689 3-[(7-Methoxy-chroman-2-ylmethyl)-amino]-propan-1-ol; oxalic acid::CHEMBL133776 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061689&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10514903 103957239 CHEMBL133776 ZINC13775941 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049874 Oc1ccc2CC[C@H](CN3CCc4ccccc4C3)Oc2c1 InChI=1S/C19H21NO2/c21-17-7-5-15-6-8-18(22-19(15)11-17)13-20-10-9-14-3-1-2-4-16(14)12-20/h1-5,7,11,18,21H,6,8-10,12-13H2/t18-/m1/s1 IWUPLAFLTUWLMF-GOSISDBHSA-N 50061681 (R)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chroman-7-ol; oxalic acid::CHEMBL135044 D(2) dopamine receptor Rattus norvegicus 0.600000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061681&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10803828 103957231 CHEMBL135044 ZINC12356067 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049875 Oc1cc2OC(CNCc3ccccc3)CCc2cc1Cl InChI=1S/C17H18ClNO2/c18-15-8-13-6-7-14(21-17(13)9-16(15)20)11-19-10-12-4-2-1-3-5-12/h1-5,8-9,14,19-20H,6-7,10-11H2 BCTPODDQZONFKA-UHFFFAOYSA-N 50061653 2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; oxalic acid::CHEMBL337228 D(2) dopamine receptor Rattus norvegicus 7.1 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061653&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9839426 103957203 CHEMBL337228 ZINC13775966 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049876 CN(CC1CCc2ccc(O)cc2O1)Cc1ccccc1 InChI=1S/C18H21NO2/c1-19(12-14-5-3-2-4-6-14)13-17-10-8-15-7-9-16(20)11-18(15)21-17/h2-7,9,11,17,20H,8,10,12-13H2,1H3 NSEJEWWJBYGEFK-UHFFFAOYSA-N 50061668 2-[(Benzyl-methyl-amino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL135291 D(2) dopamine receptor Rattus norvegicus 61 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061668&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10755425 103957218 CHEMBL135291 ZINC13775968 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049877 Oc1ccc2CCC(CNCc3ccc(F)cc3)Oc2c1 InChI=1S/C17H18FNO2/c18-14-5-1-12(2-6-14)10-19-11-16-8-4-13-3-7-15(20)9-17(13)21-16/h1-3,5-7,9,16,19-20H,4,8,10-11H2 AYQFVOWZPZLEGQ-UHFFFAOYSA-N 50061657 2-[(4-Fluoro-benzylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL334406 D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061657&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10684699 103957207 CHEMBL334406 ZINC13775972 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049878 Oc1ccc2CC[C@@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m0/s1 DWUAAOIZQFTYQP-INIZCTEOSA-N 50061667 (S)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL138016 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061667&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10801925 103957217 CHEMBL138016 ZINC13775957 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049879 Oc1cc2O[C@H](CNCc3ccccc3)CCc2cc1Cl InChI=1S/C17H18ClNO2/c18-15-8-13-6-7-14(21-17(13)9-16(15)20)11-19-10-12-4-2-1-3-5-12/h1-5,8-9,14,19-20H,6-7,10-11H2/t14-/m0/s1 BCTPODDQZONFKA-AWEZNQCLSA-N 50061659 (S)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; oxalic acid::CHEMBL134343 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061659&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10494689 103957209 CHEMBL134343 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049880 Oc1cc2O[C@@H](CNCc3ccccc3)CCc2cc1Cl InChI=1S/C17H18ClNO2/c18-15-8-13-6-7-14(21-17(13)9-16(15)20)11-19-10-12-4-2-1-3-5-12/h1-5,8-9,14,19-20H,6-7,10-11H2/t14-/m1/s1 BCTPODDQZONFKA-CQSZACIVSA-N 50061640 (R)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; oxalic acid::CHEMBL135357 D(2) dopamine receptor Rattus norvegicus 0.600000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061640&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10685891 103957190 CHEMBL135357 ZINC13775965 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049881 Oc1ccc2CCC(CNCCCOc3ccccc3)Oc2c1 InChI=1S/C19H23NO3/c21-16-9-7-15-8-10-18(23-19(15)13-16)14-20-11-4-12-22-17-5-2-1-3-6-17/h1-3,5-7,9,13,18,20-21H,4,8,10-12,14H2 OSKPDOAXGBYHKG-UHFFFAOYSA-N 50061638 2-[(3-Phenoxy-propylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL134448 D(2) dopamine receptor Rattus norvegicus 6.7 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10686667 103957188 CHEMBL134448 ZINC13775927 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049882 Oc1ccc2CCC(CNCc3ccc(Cl)cc3)Oc2c1 InChI=1S/C17H18ClNO2/c18-14-5-1-12(2-6-14)10-19-11-16-8-4-13-3-7-15(20)9-17(13)21-16/h1-3,5-7,9,16,19-20H,4,8,10-11H2 QTGAERMWSORYGD-UHFFFAOYSA-N 50061665 2-[(4-Chloro-benzylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL135873 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061665&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10518570 103957215 CHEMBL135873 ZINC13775974 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049883 OCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C13H19NO3/c15-7-1-6-14-9-12-5-3-10-2-4-11(16)8-13(10)17-12/h2,4,8,12,14-16H,1,3,5-7,9H2 YEENTVNLGWCDRF-UHFFFAOYSA-N 50061670 2-[(3-Hydroxy-propylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL336856 D(2) dopamine receptor Rattus norvegicus 3.4 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061670&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10799880 103957220 CHEMBL336856 ZINC03959257 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049884 Oc1ccc2CCC(CNCc3ccco3)Oc2c1 InChI=1S/C15H17NO3/c17-12-5-3-11-4-6-14(19-15(11)8-12)10-16-9-13-2-1-7-18-13/h1-3,5,7-8,14,16-17H,4,6,9-10H2 VGDCLOXHDNBUQX-UHFFFAOYSA-N 50061678 2-{[(Furan-2-ylmethyl)-amino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134582 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061678&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10515430 103957228 CHEMBL134582 ZINC12355978 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049885 Oc1ccc2CCC(CNCCCc3ccccc3)Oc2c1 InChI=1S/C19H23NO2/c21-17-10-8-16-9-11-18(22-19(16)13-17)14-20-12-4-7-15-5-2-1-3-6-15/h1-3,5-6,8,10,13,18,20-21H,4,7,9,11-12,14H2 UFPFTPPWVXLEQS-UHFFFAOYSA-N 50061661 2-[(3-Phenyl-propylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL135495 D(2) dopamine receptor Rattus norvegicus 0.400000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061661&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10590126 103957211 CHEMBL135495 ZINC12356077 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049886 Oc1ccc2CCC(CNCCc3ccccc3)Oc2c1 InChI=1S/C18H21NO2/c20-16-8-6-15-7-9-17(21-18(15)12-16)13-19-11-10-14-4-2-1-3-5-14/h1-6,8,12,17,19-20H,7,9-11,13H2 CPHLCRCURDQKDY-UHFFFAOYSA-N 50061674 2-(Phenethylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL135546 D(2) dopamine receptor Rattus norvegicus 0.800000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061674&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10493242 103957224 CHEMBL135546 ZINC12356040 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049887 CS(=O)(=O)Nc1ccc2CCC(CNCCCOc3cccc(N)c3)Oc2c1 InChI=1S/C20H27N3O4S/c1-28(24,25)23-17-8-6-15-7-9-19(27-20(15)13-17)14-22-10-3-11-26-18-5-2-4-16(21)12-18/h2,4-6,8,12-13,19,22-23H,3,7,9-11,14,21H2,1H3 LJCATBRSEIHKGF-UHFFFAOYSA-N 50061634 CHEMBL133833::N-(2-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-chroman-7-yl)-methanesulfonamide; oxalic acid D(2) dopamine receptor Rattus norvegicus 102 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061634&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9844212 103957184 CHEMBL133833 ZINC13775939 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049888 Cc1c(N)cccc1OCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C20H26N2O3/c1-14-18(21)4-2-5-19(14)24-11-3-10-22-13-17-9-7-15-6-8-16(23)12-20(15)25-17/h2,4-6,8,12,17,22-23H,3,7,9-11,13,21H2,1H3 JMHOWYVJMKHOJR-UHFFFAOYSA-N 50061658 2-{[3-(3-Amino-2-methyl-phenoxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134605 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061658&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10783507 103957208 CHEMBL134605 ZINC13775925 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049889 CCCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C15H23NO2/c1-2-3-4-9-16-11-14-8-6-12-5-7-13(17)10-15(12)18-14/h5,7,10,14,16-17H,2-4,6,8-9,11H2,1H3 DOZIVYHWZVQTFR-UHFFFAOYSA-N 50061656 2-Pentylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL340267 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061656&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10777026 103957206 CHEMBL340267 ZINC13775947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049893 COc1ccc2CCC(CNCCCOc3cccc(N)c3)Oc2c1 InChI=1S/C20H26N2O3/c1-23-17-8-6-15-7-9-19(25-20(15)13-17)14-22-10-3-11-24-18-5-2-4-16(21)12-18/h2,4-6,8,12-13,19,22H,3,7,9-11,14,21H2,1H3 TYIZMLIZHZSCOR-UHFFFAOYSA-N 50061686 3-{3-[(7-Methoxy-chroman-2-ylmethyl)-amino]-propoxy}-phenylamine; hydrochloride::CHEMBL541094 D(2) dopamine receptor Rattus norvegicus 1132 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645499 103957236 CHEMBL541094 ZINC13775937 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049896 Nc1cccc(OCCCNCC2CCc3ccc(O)cc3O2)c1 InChI=1S/C19H24N2O3/c20-15-3-1-4-17(11-15)23-10-2-9-21-13-18-8-6-14-5-7-16(22)12-19(14)24-18/h1,3-5,7,11-12,18,21-22H,2,6,8-10,13,20H2 VEXJEWIAHBSEBB-UHFFFAOYSA-N 50061648 2-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-chroman-7-ol; hydrochloride::CHEMBL543426 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10664055 103957198 CHEMBL543426 ZINC13775917 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049899 Oc1ccc2CCC(CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2 DWUAAOIZQFTYQP-UHFFFAOYSA-N 50061684 2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL135395 D(2) dopamine receptor Rattus norvegicus 0.200000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22910005 103957234 CHEMBL135395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049901 Oc1ccc2CC[C@@H](CN3CCc4ccccc4C3)Oc2c1 InChI=1S/C19H21NO2/c21-17-7-5-15-6-8-18(22-19(15)11-17)13-20-10-9-14-3-1-2-4-16(14)12-20/h1-5,7,11,18,21H,6,8-10,12-13H2/t18-/m0/s1 IWUPLAFLTUWLMF-SFHVURJKSA-N 50061635 (S)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chroman-7-ol; oxalic acid::CHEMBL135725 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061635&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10803829 103957185 CHEMBL135725 ZINC12356066 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049921 Nc1cccc(OCCCNCC2CCc3ccccc3O2)c1 InChI=1S/C19H24N2O2/c20-16-6-3-7-17(13-16)22-12-4-11-21-14-18-10-9-15-5-1-2-8-19(15)23-18/h1-3,5-8,13,18,21H,4,9-12,14,20H2 LZDHUMNPJASCMA-UHFFFAOYSA-N 50061685 3-{3-[(Chroman-2-ylmethyl)-amino]-propoxy}-phenylamine; oxalic acid::CHEMBL134678 D(2) dopamine receptor Rattus norvegicus 472 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061685&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10543145 103957235 CHEMBL134678 ZINC12356087 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049926 CCC(CC)NCC1CCc2ccc(O)cc2O1 InChI=1S/C15H23NO2/c1-3-12(4-2)16-10-14-8-6-11-5-7-13(17)9-15(11)18-14/h5,7,9,12,14,16-17H,3-4,6,8,10H2,1-2H3 DXGWEOVPJQPZFA-UHFFFAOYSA-N 50061663 2-[(1-Ethyl-propylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL134931 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061663&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10490854 103957213 CHEMBL134931 ZINC13775952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049928 CC(C)CCNCC1CCc2ccc(O)cc2O1 InChI=1S/C15H23NO2/c1-11(2)7-8-16-10-14-6-4-12-3-5-13(17)9-15(12)18-14/h3,5,9,11,14,16-17H,4,6-8,10H2,1-2H3 QUTOZVVXGBXVSP-UHFFFAOYSA-N 50061688 2-[(3-Methyl-butylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL134843 D(2) dopamine receptor Rattus norvegicus 1.6 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061688&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10634367 103957238 CHEMBL134843 ZINC03959256 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049930 Cc1noc2cc(OCCCNCC3CCc4ccc(O)cc4O3)ccc12 InChI=1S/C21H24N2O4/c1-14-19-8-7-17(12-21(19)27-23-14)25-10-2-9-22-13-18-6-4-15-3-5-16(24)11-20(15)26-18/h3,5,7-8,11-12,18,22,24H,2,4,6,9-10,13H2,1H3 OLYVLNMYFDULPJ-UHFFFAOYSA-N 50061646 2-{[3-(3-Methyl-benzo[d]isoxazol-6-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134930 D(2) dopamine receptor Rattus norvegicus 0.300000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061646&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9799403 103957196 CHEMBL134930 ZINC13775933 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049932 Nc1cccc(OCCCNC[C@H]2COc3ccc(O)cc3O2)c1 InChI=1S/C18H22N2O4/c19-13-3-1-4-15(9-13)22-8-2-7-20-11-16-12-23-17-6-5-14(21)10-18(17)24-16/h1,3-6,9-10,16,20-21H,2,7-8,11-12,19H2/t16-/m0/s1 XQRSLRUXPXVCRY-INIZCTEOSA-N 50061671 3-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-2,3-dihydro-benzo[1,4]dioxin-6-ol::CHEMBL136635 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061671&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9927497 103957221 CHEMBL136635 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049934 Oc1ccc2CCC(CNCc3ccncc3)Oc2c1 InChI=1S/C16H18N2O2/c19-14-3-1-13-2-4-15(20-16(13)9-14)11-18-10-12-5-7-17-8-6-12/h1,3,5-9,15,18-19H,2,4,10-11H2 CMPVSRKCPJUIRW-UHFFFAOYSA-N 50061680 2-{[(Pyridin-4-ylmethyl)-amino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL135285 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10221090 103957230 CHEMBL135285 ZINC04632551 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049946 Oc1ccc2CCC(CNCCCCc3ccccc3)Oc2c1 InChI=1S/C20H25NO2/c22-18-11-9-17-10-12-19(23-20(17)14-18)15-21-13-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9,11,14,19,21-22H,4-5,8,10,12-13,15H2 FIKHCMJSJBBEJM-UHFFFAOYSA-N 50061632 2-[(4-Phenyl-butylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL134663 D(2) dopamine receptor Rattus norvegicus 0.600000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061632&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10662838 103957182 CHEMBL134663 ZINC13775956 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049953 Cc1ccc(OCCCNCC2CCc3ccc(O)cc3O2)cc1N InChI=1S/C20H26N2O3/c1-14-3-7-17(12-19(14)21)24-10-2-9-22-13-18-8-5-15-4-6-16(23)11-20(15)25-18/h3-4,6-7,11-12,18,22-23H,2,5,8-10,13,21H2,1H3 DTJUYOKAKLONJT-UHFFFAOYSA-N 50061655 2-{[3-(3-Amino-4-methyl-phenoxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134281 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061655&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10497505 103957205 CHEMBL134281 ZINC13775929 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049959 Oc1ccc2CCC(CNCCCOc3cccc4[nH]ccc34)Oc2c1 InChI=1S/C21H24N2O3/c24-16-7-5-15-6-8-17(26-21(15)13-16)14-22-10-2-12-25-20-4-1-3-19-18(20)9-11-23-19/h1,3-5,7,9,11,13,17,22-24H,2,6,8,10,12,14H2 MSCOCRBMEUIKRL-UHFFFAOYSA-N 50061675 2-{[3-(1H-Indol-4-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134707 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061675&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10641733 103957225 CHEMBL134707 ZINC12356190 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049964 CCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C14H21NO2/c1-2-3-8-15-10-13-7-5-11-4-6-12(16)9-14(11)17-13/h4,6,9,13,15-16H,2-3,5,7-8,10H2,1H3 PLFNWLNAVFWLFO-UHFFFAOYSA-N 50061644 2-Butylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135116 D(2) dopamine receptor Rattus norvegicus 62 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10799761 103957194 CHEMBL135116 ZINC03959252 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049971 Nc1nc2CCN(CC=C)CCc2s1 InChI=1S/C10H15N3S/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8/h2H,1,3-7H2,(H2,11,12) DHSSDEDRBUKTQY-UHFFFAOYSA-N 86053 B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5374 136352153 CHEMBL279085 ZINC00006644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049976 OCCCNCC1CCc2ccccc2O1 InChI=1S/C13H19NO2/c15-9-3-8-14-10-12-7-6-11-4-1-2-5-13(11)16-12/h1-2,4-5,12,14-15H,3,6-10H2 FUWHJYUJXZYSCO-UHFFFAOYSA-N 50061641 3-[(Chroman-2-ylmethyl)-amino]-propan-1-ol; hydrochloride::CHEMBL545078 D(2) dopamine receptor Rattus norvegicus 2763 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061641&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44356021 103957191 CHEMBL545078 ZINC13775943 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049977 Oc1ccc2CCC(CN3CCc4ccccc4C3)Oc2c1 InChI=1S/C19H21NO2/c21-17-7-5-15-6-8-18(22-19(15)11-17)13-20-10-9-14-3-1-2-4-16(14)12-20/h1-5,7,11,18,21H,6,8-10,12-13H2 IWUPLAFLTUWLMF-UHFFFAOYSA-N 50061654 2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chroman-7-ol; oxalic acid::CHEMBL134808 D(2) dopamine receptor Rattus norvegicus 3.2 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061654&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44356253 103957204 CHEMBL134808 ZINC12356067 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50050008 Oc1ccc2CCC(CNCCCOc3ccc4ocnc4c3)Oc2c1 InChI=1S/C20H22N2O4/c23-15-4-2-14-3-5-17(26-20(14)10-15)12-21-8-1-9-24-16-6-7-19-18(11-16)22-13-25-19/h2,4,6-7,10-11,13,17,21,23H,1,3,5,8-9,12H2 DAQQNLJMVSQRSY-UHFFFAOYSA-N 50061649 2-{[3-(Benzooxazol-5-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134677 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10665823 103957199 CHEMBL134677 ZINC13775931 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50050009 Oc1ccc2CC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m1/s1 DWUAAOIZQFTYQP-MRXNPFEDSA-N 50061669 (R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL134807::CHEMBL64553 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378389 103957219 CHEMBL134807CHEMBL64553 ZINC13527706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50050010 Nc1cccc(OCCCNC[C@@H]2COc3ccc(O)cc3O2)c1 InChI=1S/C18H22N2O4/c19-13-3-1-4-15(9-13)22-8-2-7-20-11-16-12-23-17-6-5-14(21)10-18(17)24-16/h1,3-6,9-10,16,20-21H,2,7-8,11-12,19H2/t16-/m1/s1 XQRSLRUXPXVCRY-MRXNPFEDSA-N 50061651 (R)-3-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-2,3-dihydro-benzo[1,4]dioxin-6-ol::CHEMBL423335 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44355732 103957201 CHEMBL423335 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50050011 Oc1ccc2CCC(CNCCCOc3ccc4cccnc4c3)Oc2c1 InChI=1S/C22H24N2O3/c25-18-7-4-17-6-9-20(27-22(17)13-18)15-23-10-2-12-26-19-8-5-16-3-1-11-24-21(16)14-19/h1,3-5,7-8,11,13-14,20,23,25H,2,6,9-10,12,15H2 CPMKULWZFNXOBS-UHFFFAOYSA-N 50061673 2-{[3-(Quinolin-7-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL135183 D(2) dopamine receptor Rattus norvegicus 0.500000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061673&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594944 103957223 CHEMBL135183 ZINC13775921 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50050014 Nc1cccc(OCCCNCC2CCc3ccc(O)cc3C2)c1 InChI=1S/C20H26N2O2/c21-18-3-1-4-20(13-18)24-10-2-9-22-14-15-5-6-16-7-8-19(23)12-17(16)11-15/h1,3-4,7-8,12-13,15,22-23H,2,5-6,9-11,14,21H2 RUTCZVPJACQPHP-UHFFFAOYSA-N 50061647 7-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-5,6,7,8-tetrahydro-naphthalen-2-ol; oxalic acid::CHEMBL135864 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10568152 103957197 CHEMBL135864 ZINC13775919 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50050015 Oc1ccc2CCC(CNC3CCCCC3)Oc2c1 InChI=1S/C16H23NO2/c18-14-8-6-12-7-9-15(19-16(12)10-14)11-17-13-4-2-1-3-5-13/h6,8,10,13,15,17-18H,1-5,7,9,11H2 AFXVAXQMGUXVBX-UHFFFAOYSA-N 50061672 2-Cyclohexylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135011 D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10563379 103957222 CHEMBL135011 ZINC13775954 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50050016 Oc1ccc2CCC(CNCCCOc3ccc4CCCNc4c3)Oc2c1 InChI=1S/C22H28N2O3/c25-18-7-4-17-6-9-20(27-22(17)13-18)15-23-10-2-12-26-19-8-5-16-3-1-11-24-21(16)14-19/h4-5,7-8,13-14,20,23-25H,1-3,6,9-12,15H2 JOGUPOAVWOLLLX-UHFFFAOYSA-N 50061643 2-{[3-(1,2,3,4-Tetrahydro-quinolin-7-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL424087 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10571059 103957193 CHEMBL424087 ZINC12356233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50050017 CCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C13H19NO2/c1-2-7-14-9-12-6-4-10-3-5-11(15)8-13(10)16-12/h3,5,8,12,14-15H,2,4,6-7,9H2,1H3 PEHTUJKNDCNRDK-UHFFFAOYSA-N 50061652 2-Propylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135636 D(2) dopamine receptor Rattus norvegicus 96 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061652&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10513189 103957202 CHEMBL135636 ZINC03959253 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50050314 OC[C@H]1COc2c(O1)cccc2N1CCN(CCNC(=O)c2ccc(F)cc2)CC1 InChI=1S/C22H26FN3O4/c23-17-6-4-16(5-7-17)22(28)24-8-9-25-10-12-26(13-11-25)19-2-1-3-20-21(19)29-15-18(14-27)30-20/h1-7,18,27H,8-15H2,(H,24,28)/t18-/m0/s1 NYSDRDDQELAVKP-SFHVURJKSA-N 50454759 Flesinoxan D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454759&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57347 225146319 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051498 COc1cccc2C(CCCc12)SCCN1CCN(CC1)c1ccccc1OC InChI=1S/C24H32N2O2S/c1-27-22-11-5-8-20-19(22)7-6-12-24(20)29-18-17-25-13-15-26(16-14-25)21-9-3-4-10-23(21)28-2/h3-5,8-11,24H,6-7,12-18H2,1-2H3 XMEWZTDTPHMFTH-UHFFFAOYSA-N 50033836 1-(2-Methoxy-phenyl)-4-[2-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylsulfanyl)-ethyl]-piperazine::CHEMBL174703 D(2) dopamine receptor Rattus norvegicus 7.83 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033836&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10409457 103942084 CHEMBL174703 ZINC13740688 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051500 COc1cccc2\C(CCCc12)=C\CCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H32N2O2/c1-28-24-14-6-10-21-20(8-5-11-22(21)24)9-7-15-26-16-18-27(19-17-26)23-12-3-4-13-25(23)29-2/h3-4,6,9-10,12-14H,5,7-8,11,15-19H2,1-2H3/b20-9+ KUQPEURUYNWBAE-AWQFTUOYSA-N 50033833 1-{3-[5-Methoxy-3,4-dihydro-2H-naphthalen-(1E)-ylidene]-propyl}-4-(2-methoxy-phenyl)-piperazine::CHEMBL173190 D(2) dopamine receptor Rattus norvegicus 11.3 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033833&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10475634 103942081 CHEMBL173190 ZINC13740666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051515 COc1cccc2\C(CCCc12)=C\CCN1CCN(CC1)c1ccccn1 InChI=1S/C23H29N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-3,5,8-9,11-13H,4,6-7,10,14-18H2,1H3/b19-8+ MEJDASWPPCVZOR-UFWORHAWSA-N 50033843 1-[3-(5-Methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)-propyl]-4-pyridin-2-yl-piperazine::1-{3-[5-Methoxy-3,4-dihydro-2H-naphthalen-(1E)-ylidene]-propyl}-4-pyridin-2-yl-piperazine::CHEMBL140406 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10248163 103942091 CHEMBL140406 ZINC13470666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051520 COc1ccccc1N1CCN(CC\C=C2/CCCc3ccccc23)CC1 InChI=1S/C24H30N2O/c1-27-24-14-5-4-13-23(24)26-18-16-25(17-19-26)15-7-11-21-10-6-9-20-8-2-3-12-22(20)21/h2-5,8,11-14H,6-7,9-10,15-19H2,1H3/b21-11+ NWZQVOAMBHTGNW-SRZZPIQSSA-N 50033844 1-{3-[3,4-Dihydro-2H-naphthalen-(1E)-ylidene]-propyl}-4-(2-methoxy-phenyl)-piperazine::CHEMBL174300 D(2) dopamine receptor Rattus norvegicus 12.7 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10384067 103942092 CHEMBL174300 ZINC13740665 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051529 COc1ccc2CCCC(CCCCN3CCN(CC3)c3ccccc3OC)c2c1 InChI=1S/C26H36N2O2/c1-29-23-14-13-22-10-7-9-21(24(22)20-23)8-5-6-15-27-16-18-28(19-17-27)25-11-3-4-12-26(25)30-2/h3-4,11-14,20-21H,5-10,15-19H2,1-2H3 OKYMMNZLKVUQRW-UHFFFAOYSA-N 50033842 1-(2-Methoxy-phenyl)-4-[4-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperazine::CHEMBL172363 D(2) dopamine receptor Rattus norvegicus 50.9 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033842&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10070045 103942090 CHEMBL172363 ZINC13740678 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051532 COc1ccc2CCCC(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)c2c1 InChI=1S/C25H31F3N2O/c1-31-23-11-10-20-6-2-5-19(24(20)18-23)7-4-12-29-13-15-30(16-14-29)22-9-3-8-21(17-22)25(26,27)28/h3,8-11,17-19H,2,4-7,12-16H2,1H3 XGJBTUNWSSZAJD-UHFFFAOYSA-N 50033832 1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL367723 D(2) dopamine receptor Rattus norvegicus 1330 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033832&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10342773 103942080 CHEMBL367723 ZINC13740696 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051534 COc1ccc2CCCC(SCCN3CCN(CC3)c3ccccc3OC)c2c1 InChI=1S/C24H32N2O2S/c1-27-20-11-10-19-6-5-9-24(21(19)18-20)29-17-16-25-12-14-26(15-13-25)22-7-3-4-8-23(22)28-2/h3-4,7-8,10-11,18,24H,5-6,9,12-17H2,1-2H3 AMNJEUCLKUVQHU-UHFFFAOYSA-N 50033849 1-(2-Methoxy-phenyl)-4-[2-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylsulfanyl)-ethyl]-piperazine::CHEMBL172556 D(2) dopamine receptor Rattus norvegicus 50.2 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033849&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10070289 103942097 CHEMBL172556 ZINC13740686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051536 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 0.5 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051541 COc1cccc2C(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)CCCc12 InChI=1S/C25H31F3N2O/c1-31-24-12-4-10-22-19(6-2-11-23(22)24)7-5-13-29-14-16-30(17-15-29)21-9-3-8-20(18-21)25(26,27)28/h3-4,8-10,12,18-19H,2,5-7,11,13-17H2,1H3 SGNFTTRKPWKHRW-UHFFFAOYSA-N 50033855 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL176819 D(2) dopamine receptor Rattus norvegicus 472.0 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10388096 103942103 CHEMBL176819 ZINC13740698 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051546 COc1ccc2CCCC(CCCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C24H32N2O/c1-27-23-13-12-21-8-5-7-20(24(21)19-23)9-6-14-25-15-17-26(18-16-25)22-10-3-2-4-11-22/h2-4,10-13,19-20H,5-9,14-18H2,1H3 VEQQYRMROCWKNF-UHFFFAOYSA-N 50033854 1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL172601 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406491 103942102 CHEMBL172601 ZINC13740692 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051549 COc1ccc2CCC=C(CCCN3CCN(CC3)c3ccccn3)c2c1 InChI=1S/C23H29N3O/c1-27-21-11-10-20-7-4-6-19(22(20)18-21)8-5-13-25-14-16-26(17-15-25)23-9-2-3-12-24-23/h2-3,6,9-12,18H,4-5,7-8,13-17H2,1H3 DDSQFXURFLIECO-UHFFFAOYSA-N 50033856 1-[3-(7-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL277302 D(2) dopamine receptor Rattus norvegicus 778 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10248164 103942104 CHEMBL277302 ZINC13733288 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051551 COc1cccc2C(CCCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C26H36N2O2/c1-29-25-15-8-11-22-21(10-7-12-23(22)25)9-5-6-16-27-17-19-28(20-18-27)24-13-3-4-14-26(24)30-2/h3-4,8,11,13-15,21H,5-7,9-10,12,16-20H2,1-2H3 FKAHRAYTSLFRRL-UHFFFAOYSA-N 50033835 1-(2-Methoxy-phenyl)-4-[4-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperazine::CHEMBL28209 D(2) dopamine receptor Rattus norvegicus 15.4 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10001519 103942083 CHEMBL28209 ZINC13740680 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051558 COc1cccc2C(CCCCN3CCN(CC3)c3ccccc3OC)=CCCc12 InChI=1S/C26H34N2O2/c1-29-25-15-8-11-22-21(10-7-12-23(22)25)9-5-6-16-27-17-19-28(20-18-27)24-13-3-4-14-26(24)30-2/h3-4,8,10-11,13-15H,5-7,9,12,16-20H2,1-2H3 FDLXYGCUGATCMA-UHFFFAOYSA-N 50033848 1-[4-(5-Methoxy-3,4-dihydro-naphthalen-1-yl)-butyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL174554 D(2) dopamine receptor Rattus norvegicus 5920 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742092 103942096 CHEMBL174554 ZINC13740668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051561 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3OC)=CCCc12 InChI=1S/C25H32N2O2/c1-28-24-14-6-10-21-20(8-5-11-22(21)24)9-7-15-26-16-18-27(19-17-26)23-12-3-4-13-25(23)29-2/h3-4,6,8,10,12-14H,5,7,9,11,15-19H2,1-2H3 GNEXYDKXZDQGAN-UHFFFAOYSA-N 50033838 1-[3-(5-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL172161 D(2) dopamine receptor Rattus norvegicus 17.4 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033838&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 192639 103942086 CHEMBL172161 ZINC03651136 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051565 COc1ccc2CCC=C(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)c2c1 InChI=1S/C25H29F3N2O/c1-31-23-11-10-20-6-2-5-19(24(20)18-23)7-4-12-29-13-15-30(16-14-29)22-9-3-8-21(17-22)25(26,27)28/h3,5,8-11,17-18H,2,4,6-7,12-16H2,1H3 CEYYNGCQKHKNRD-UHFFFAOYSA-N 50033840 1-[3-(7-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL433972 D(2) dopamine receptor Rattus norvegicus 1290 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033840&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025711 103942088 CHEMBL433972 ZINC13733297 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051568 COc1ccc2CCC=C(CCCCN3CCN(CC3)c3ccccc3OC)c2c1 InChI=1S/C26H34N2O2/c1-29-23-14-13-22-10-7-9-21(24(22)20-23)8-5-6-15-27-16-18-28(19-17-27)25-11-3-4-12-26(25)30-2/h3-4,9,11-14,20H,5-8,10,15-19H2,1-2H3 HBJIMGXWEHAIDQ-UHFFFAOYSA-N 50033831 1-[4-(7-Methoxy-3,4-dihydro-naphthalen-1-yl)-butyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL366459 D(2) dopamine receptor Rattus norvegicus 10.6 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033831&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10250792 103942079 CHEMBL366459 ZINC13740667 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051575 COc1cccc2C(CCCc12)NCCN1CCN(CC1)c1ccccc1OC InChI=1S/C24H33N3O2/c1-28-23-12-6-7-19-20(23)8-5-9-21(19)25-13-14-26-15-17-27(18-16-26)22-10-3-4-11-24(22)29-2/h3-4,6-7,10-12,21,25H,5,8-9,13-18H2,1-2H3 FVDGLILSFMGSJG-UHFFFAOYSA-N 50033847 CHEMBL108241::{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine D(2) dopamine receptor Rattus norvegicus 618 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10453320 103942095 CHEMBL108241 ZINC22937544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051579 COc1ccccc1N1CCN(CCCC2CCCc3ccsc23)CC1 InChI=1S/C22H30N2OS/c1-25-21-10-3-2-9-20(21)24-15-13-23(14-16-24)12-5-8-18-6-4-7-19-11-17-26-22(18)19/h2-3,9-11,17-18H,4-8,12-16H2,1H3 LDTVGAHUVYKQFB-UHFFFAOYSA-N 50033859 1-(2-Methoxy-phenyl)-4-[3-(4,5,6,7-tetrahydro-benzo[b]thiophen-7-yl)-propyl]-piperazine::CHEMBL174083 D(2) dopamine receptor Rattus norvegicus 24.1 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385319 103942107 CHEMBL174083 ZINC13740676 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051580 COc1cccc2C(CCCN3CCN(CC3)c3ccccn3)CCCc12 InChI=1S/C23H31N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-3,5,9,11-13,19H,4,6-8,10,14-18H2,1H3 KKPMYWNQZNRGIK-UHFFFAOYSA-N 50033852 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL444590 D(2) dopamine receptor Rattus norvegicus 177 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10474042 103942100 CHEMBL444590 ZINC13470658 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051581 COc1ccccc1N1CCN(CCCC2CCCc3ccccc23)CC1 InChI=1S/C24H32N2O/c1-27-24-14-5-4-13-23(24)26-18-16-25(17-19-26)15-7-11-21-10-6-9-20-8-2-3-12-22(20)21/h2-5,8,12-14,21H,6-7,9-11,15-19H2,1H3 HIHMWBRIJRFADD-UHFFFAOYSA-N 50033851 1-(2-Methoxy-phenyl)-4-[3-(1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL368477 D(2) dopamine receptor Rattus norvegicus 24.7 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10067369 103942099 CHEMBL368477 ZINC13740670 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051592 COc1cccc2C(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)=CCCc12 InChI=1S/C25H29F3N2O/c1-31-24-12-4-10-22-19(6-2-11-23(22)24)7-5-13-29-14-16-30(17-15-29)21-9-3-8-20(18-21)25(26,27)28/h3-4,6,8-10,12,18H,2,5,7,11,13-17H2,1H3 SYKZOUNLFRNQDR-UHFFFAOYSA-N 50033837 1-[3-(5-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL171974 D(2) dopamine receptor Rattus norvegicus 644 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033837&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025712 103942085 CHEMBL171974 ZINC13733311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051597 COc1ccc2CCCC(CCCN3CCN(CC3)c3ccccc3OC)c2c1 InChI=1S/C25H34N2O2/c1-28-22-13-12-21-8-5-7-20(23(21)19-22)9-6-14-26-15-17-27(18-16-26)24-10-3-4-11-25(24)29-2/h3-4,10-13,19-20H,5-9,14-18H2,1-2H3 CCYRVZGWDNSBAQ-UHFFFAOYSA-N 50033858 1-(2-Methoxy-phenyl)-4-[3-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL424125 D(2) dopamine receptor Rattus norvegicus 51.5 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10092041 103942106 CHEMBL424125 ZINC13740672 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051603 COc1ccc2CCC=C(CCCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C24H30N2O/c1-27-23-13-12-21-8-5-7-20(24(21)19-23)9-6-14-25-15-17-26(18-16-25)22-10-3-2-4-11-22/h2-4,7,10-13,19H,5-6,8-9,14-18H2,1H3 GFPSKAXAVWQUOE-UHFFFAOYSA-N 50033845 1-[3-(7-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL143110 D(2) dopamine receptor Rattus norvegicus 777 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406366 103942093 CHEMBL143110 ZINC13733291 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051604 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 226 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051605 COc1ccc2CCC=C(CCCN3CCN(CC3)c3ccccc3OC)c2c1 InChI=1S/C25H32N2O2/c1-28-22-13-12-21-8-5-7-20(23(21)19-22)9-6-14-26-15-17-27(18-16-26)24-10-3-4-11-25(24)29-2/h3-4,7,10-13,19H,5-6,8-9,14-18H2,1-2H3 MXEYHCIDRRWILS-UHFFFAOYSA-N 50033834 1-[3-(7-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL367435 D(2) dopamine receptor Rattus norvegicus 90.6 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033834&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 192638 103942082 CHEMBL367435 ZINC00598816 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051608 COc1cccc2C(CCCN3CCN(CC3)c3ccccn3)=CCCc12 InChI=1S/C23H29N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-3,5,7,9,11-13H,4,6,8,10,14-18H2,1H3 BNFNIRJQEHBDDG-UHFFFAOYSA-N 50033853 1-[3-(5-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL175300 D(2) dopamine receptor Rattus norvegicus 119 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9975973 103942101 CHEMBL175300 ZINC28100426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051619 COc1ccc2CCCC(NCCN3CCN(CC3)c3ccccc3OC)c2c1 InChI=1S/C24H33N3O2/c1-28-20-11-10-19-6-5-7-22(21(19)18-20)25-12-13-26-14-16-27(17-15-26)23-8-3-4-9-24(23)29-2/h3-4,8-11,18,22,25H,5-7,12-17H2,1-2H3 JCKQMQMMZHMRFM-UHFFFAOYSA-N 50033846 CHEMBL425134::{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033846&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10408398 103942094 CHEMBL425134 ZINC22937537 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051626 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3)=CCCc12 InChI=1S/C24H30N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h2-4,6,8,10-12,14H,5,7,9,13,15-19H2,1H3 XOBUAHLUTFRWNA-UHFFFAOYSA-N 50033850 1-[3-(5-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL148055 D(2) dopamine receptor Rattus norvegicus 303 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033850&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10021562 103942098 CHEMBL148055 ZINC13733303 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051629 COc1ccc2CCCC(CCCN3CCN(CC3)c3ccccn3)c2c1 InChI=1S/C23H31N3O/c1-27-21-11-10-20-7-4-6-19(22(20)18-21)8-5-13-25-14-16-26(17-15-25)23-9-2-3-12-24-23/h2-3,9-12,18-19H,4-8,13-17H2,1H3 NXLCQCUSLGWBEP-UHFFFAOYSA-N 50033841 1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL171181 D(2) dopamine receptor Rattus norvegicus 328.0 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033841&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10090269 103942089 CHEMBL171181 ZINC13740690 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051636 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3)CCCc12 InChI=1S/C24H32N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h2-4,6,10-12,14,20H,5,7-9,13,15-19H2,1H3 JGCUFOXBUYJGBX-UHFFFAOYSA-N 50033857 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL322275 D(2) dopamine receptor Rattus norvegicus 96.7 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10361439 103942105 CHEMBL322275 ZINC13740694 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50051642 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C25H34N2O2/c1-28-24-14-6-10-21-20(8-5-11-22(21)24)9-7-15-26-16-18-27(19-17-26)23-12-3-4-13-25(23)29-2/h3-4,6,10,12-14,20H,5,7-9,11,15-19H2,1-2H3 INGWKGCHJJYQIB-UHFFFAOYSA-N 50033839 1-(2-Methoxy-phenyl)-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL26929 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00006a013 10.7270/Q2SQ8ZD0 7699710 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10385977 103942087 CHEMBL26929 ZINC13740674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50050667 CN(C)CCc1c[nH]c2ccc(C[C@H]3COC(=O)N3)cc12 InChI=1S/C16H21N3O2/c1-19(2)6-5-12-9-17-15-4-3-11(8-14(12)15)7-13-10-21-16(20)18-13/h3-4,8-9,13,17H,5-7,10H2,1-2H3,(H,18,20)/t13-/m0/s1 ULSDMUVEXKOYBU-ZDUSSCGKSA-N 50033383 (S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)methyl)oxazolidin-2-one::(S)-4-[3-(2-Dimethylamino-ethyl)-1H-indol-5-ylmethyl]-oxazolidin-2-one::311C90::CHEMBL1185::ZOLMITRIPTAN::ZOMIG::ZOMIG-ZMT D(2) dopamine receptor Rattus norvegicus 0.04 ChEMBL 10.1021/jm00018a016 10.7270/Q2GF0SJ4 7658443 Glen, RC; Martin, GR; Hill, AP; Hyde, RM; Woollard, PM; Salmon, JA; Buckingham, J; Robertson, AD Wellcome Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60857 103941674 10124 CHEMBL1185 DB00315 60 ZINC00015515 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50052933 COc1ccc(CCCCNCCOc2cc(F)cc3C(O)CCOc23)cc1 InChI=1S/C22H28FNO4/c1-26-18-7-5-16(6-8-18)4-2-3-10-24-11-13-27-21-15-17(23)14-19-20(25)9-12-28-22(19)21/h5-8,14-15,20,24-25H,2-4,9-13H2,1H3 GQVNYCJRZSTERX-UHFFFAOYSA-N 50065563 6-Fluoro-8-{2-[4-(4-methoxy-phenyl)-butylamino]-ethoxy}-chroman-4-ol::CHEMBL96714 D(2) dopamine receptor Rattus norvegicus 0.724 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44212473 103960443 CHEMBL96714 ZINC13780382 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049853 CS(=O)(=O)Nc1ccc2CCC(CNCCCO)Oc2c1 InChI=1S/C14H22N2O4S/c1-21(18,19)16-12-5-3-11-4-6-13(20-14(11)9-12)10-15-7-2-8-17/h3,5,9,13,15-17H,2,4,6-8,10H2,1H3 FONSKAIHCFLVMC-UHFFFAOYSA-N 50061683 CHEMBL135297::N-{2-[(3-Hydroxy-propylamino)-methyl]-chroman-7-yl}-methanesulfonamide; oxalic acid D(2) dopamine receptor Rattus norvegicus 102 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061683&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10591372 103957233 CHEMBL135297 ZINC13775945 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049854 CS(=O)(=O)Nc1ccc2CCC(CNCc3ccccc3)Oc2c1 InChI=1S/C18H22N2O3S/c1-24(21,22)20-16-9-7-15-8-10-17(23-18(15)11-16)13-19-12-14-5-3-2-4-6-14/h2-7,9,11,17,19-20H,8,10,12-13H2,1H3 LOXIOAISACXTLR-UHFFFAOYSA-N 50061664 CHEMBL337696::N-[2-(Benzylamino-methyl)-chroman-7-yl]-methanesulfonamide; oxalic acid D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061664&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593705 103957214 CHEMBL337696 ZINC13775964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049855 Oc1ccc2CCC(CNCc3cccc4ccccc34)Oc2c1 InChI=1S/C21H21NO2/c23-18-10-8-16-9-11-19(24-21(16)12-18)14-22-13-17-6-3-5-15-4-1-2-7-20(15)17/h1-8,10,12,19,22-23H,9,11,13-14H2 QLJKVRVRUHCBTI-UHFFFAOYSA-N 50061666 2-{[(Naphthalen-1-ylmethyl)-amino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL135242 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061666&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10567650 103957216 CHEMBL135242 ZINC13775962 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049856 Nc1nccc(OCCCNCC2CCc3ccc(O)cc3O2)n1 InChI=1S/C17H22N4O3/c18-17-20-8-6-16(21-17)23-9-1-7-19-11-14-5-3-12-2-4-13(22)10-15(12)24-14/h2,4,6,8,10,14,19,22H,1,3,5,7,9,11H2,(H2,18,20,21) FZGKVKJMAJFNHI-UHFFFAOYSA-N 50061662 2-{[3-(2-Amino-pyrimidin-4-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134725 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061662&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640173 103957212 CHEMBL134725 ZINC13775935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049857 Cc1ccc(CNCC2CCc3ccc(NS(C)(=O)=O)cc3O2)cc1 InChI=1S/C19H24N2O3S/c1-14-3-5-15(6-4-14)12-20-13-18-10-8-16-7-9-17(11-19(16)24-18)21-25(2,22)23/h3-7,9,11,18,20-21H,8,10,12-13H2,1-2H3 DPKPCJJKKOEQBE-UHFFFAOYSA-N 50061645 CHEMBL133367::N-{2-[(4-Methyl-benzylamino)-methyl]-chroman-7-yl}-methanesulfonamide; oxalic acid D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061645&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10666241 103957195 CHEMBL133367 ZINC13775978 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049858 Nc1cc(OCCCNCC2CCc3ccc(O)cc3O2)ccc1Cl InChI=1S/C19H23ClN2O3/c20-17-7-6-15(11-18(17)21)24-9-1-8-22-12-16-5-3-13-2-4-14(23)10-19(13)25-16/h2,4,6-7,10-11,16,22-23H,1,3,5,8-9,12,21H2 AVVHLOOXCWDKCY-UHFFFAOYSA-N 50061636 2-{[3-(3-Amino-4-chloro-phenoxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL135201 D(2) dopamine receptor Rattus norvegicus 0.300000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594856 103957186 CHEMBL135201 ZINC13775923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049859 Oc1ccc2OC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C16H17NO3/c18-13-6-7-15-16(8-13)20-14(11-19-15)10-17-9-12-4-2-1-3-5-12/h1-8,14,17-18H,9-11H2/t14-/m0/s1 DYWYWIOQKKRAST-AWEZNQCLSA-N 50061642 (S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]dioxin-6-ol; oxalic acid::CHEMBL300571::CHEMBL423890 D(2) dopamine receptor Rattus norvegicus 0.400000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10612157 103957192 CHEMBL300571CHEMBL423890 ZINC13775979 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049860 Oc1ccc(CNCC2CCc3ccc(O)cc3O2)cc1 InChI=1S/C17H19NO3/c19-14-5-1-12(2-6-14)10-18-11-16-8-4-13-3-7-15(20)9-17(13)21-16/h1-3,5-7,9,16,18-20H,4,8,10-11H2 COAJRUUAHDYFLT-UHFFFAOYSA-N 50061633 2-[(4-Hydroxy-benzylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL339190 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061633&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10565066 103957183 CHEMBL339190 ZINC13775976 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049861 CCCCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C16H25NO2/c1-2-3-4-5-10-17-12-15-9-7-13-6-8-14(18)11-16(13)19-15/h6,8,11,15,17-18H,2-5,7,9-10,12H2,1H3 QNPXMHDZEWNMNS-UHFFFAOYSA-N 50061679 2-Hexylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135222 D(2) dopamine receptor Rattus norvegicus 0.700000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10220913 103957229 CHEMBL135222 ZINC03959251 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049862 CN1C[C@H](C[C@H]2[C@H]1Cc1c(C)[nH]c3cccc2c13)NC(=O)C(C)(C)C InChI=1S/C21H29N3O/c1-12-15-10-18-16(14-7-6-8-17(22-12)19(14)15)9-13(11-24(18)5)23-20(25)21(2,3)4/h6-8,13,16,18,22H,9-11H2,1-5H3,(H,23,25)/t13-,16+,18+/m0/s1 ZNMWUMGOSWLWOH-FDQGKXFDSA-N 50061687 CHEMBL336390::N-((6aR,9S,10aR)-5,7-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-2,2-dimethyl-propionamide D(2) dopamine receptor Rattus norvegicus 0.900000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061687&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 148841 103957237 CHEMBL336390 ZINC03802834 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049863 Nc1cccc(OCCCNCC2COc3ccc(O)cc3O2)c1 InChI=1S/C18H22N2O4/c19-13-3-1-4-15(9-13)22-8-2-7-20-11-16-12-23-17-6-5-14(21)10-18(17)24-16/h1,3-6,9-10,16,20-21H,2,7-8,11-12,19H2 XQRSLRUXPXVCRY-UHFFFAOYSA-N 50061650 3-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-2,3-dihydro-benzo[1,4]dioxin-6-ol::CHEMBL135752 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061650&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9949399 103957200 CHEMBL135752 ZINC03779080 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049866 CC(C)NCC1CCc2ccc(O)cc2O1 InChI=1S/C13H19NO2/c1-9(2)14-8-12-6-4-10-3-5-11(15)7-13(10)16-12/h3,5,7,9,12,14-15H,4,6,8H2,1-2H3 LYVQVYJGNYDXHG-UHFFFAOYSA-N 50061676 2-(Isopropylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL132811 D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061676&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10609019 103957226 CHEMBL132811 ZINC13775949 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049867 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 702 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049868 Oc1ccc2CCC(CNCC3CCCCC3)Oc2c1 InChI=1S/C17H25NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h6,8,10,13,16,18-19H,1-5,7,9,11-12H2 QBNAZFPOIWIARB-UHFFFAOYSA-N 50061660 2-[(Cyclohexylmethyl-amino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL135137 D(2) dopamine receptor Rattus norvegicus 0.900000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061660&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10826275 103957210 CHEMBL135137 ZINC13775960 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049869 Oc1ccc2CC[C@H](CNCCCCc3ccccc3)Oc2c1 InChI=1S/C20H25NO2/c22-18-11-9-17-10-12-19(23-20(17)14-18)15-21-13-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9,11,14,19,21-22H,4-5,8,10,12-13,15H2/t19-/m1/s1 FIKHCMJSJBBEJM-LJQANCHMSA-N 50061682 (R)-2-[(4-Phenyl-butylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL134489 D(2) dopamine receptor Rattus norvegicus 0.200000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061682&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10591141 103957232 CHEMBL134489 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049870 CC(C)CNCC1CCc2ccc(O)cc2O1 InChI=1S/C14H21NO2/c1-10(2)8-15-9-13-6-4-11-3-5-12(16)7-14(11)17-13/h3,5,7,10,13,15-16H,4,6,8-9H2,1-2H3 SQAQEPLVGLAOHM-UHFFFAOYSA-N 50061637 2-(Isobutylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL135269 D(2) dopamine receptor Rattus norvegicus 372 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10633524 103957187 CHEMBL135269 ZINC13775950 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049871 Oc1ccc2CCC(CNCc3cccs3)Oc2c1 InChI=1S/C15H17NO2S/c17-12-5-3-11-4-6-13(18-15(11)8-12)9-16-10-14-2-1-7-19-14/h1-3,5,7-8,13,16-17H,4,6,9-10H2 KBNHFHXXRALJJY-UHFFFAOYSA-N 50061639 2-{[(Thiophen-2-ylmethyl)-amino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL337724 D(2) dopamine receptor Rattus norvegicus 0.600000 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061639&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10850012 103957189 CHEMBL337724 ZINC13775959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50049872 Oc1ccc2CCC(CNCCCOc3ccc4ncoc4c3)Oc2c1 InChI=1S/C20H22N2O4/c23-15-4-2-14-3-5-17(26-19(14)10-15)12-21-8-1-9-24-16-6-7-18-20(11-16)25-13-22-18/h2,4,6-7,10-11,13,17,21,23H,1,3,5,8-9,12H2 PPSUFDUYMIFSSO-UHFFFAOYSA-N 50061631 2-{[3-(Benzooxazol-6-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL334616 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061631&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10784316 103957181 CHEMBL334616 ZINC12356188 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057463 Clc1ccc2c(noc2c1)C1CCN(CCNC(=O)c2nsc3ccccc23)CC1 InChI=1S/C22H21ClN4O2S/c23-15-5-6-16-18(13-15)29-25-20(16)14-7-10-27(11-8-14)12-9-24-22(28)21-17-3-1-2-4-19(17)30-26-21/h1-6,13-14H,7-12H2,(H,24,28) SKJNVPGYOBEJTP-UHFFFAOYSA-N 50036904 Benzo[d]isothiazole-3-carboxylic acid {2-[4-(6-chloro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-amide::CHEMBL306141 D(2) dopamine receptor Rattus norvegicus 711.6 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036904&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10071972 103944545 CHEMBL306141 ZINC13737874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057467 COc1ccccc1N1CCN(CCCN(C)C(=O)c2nsc3ccccc23)CC1 InChI=1S/C23H28N4O2S/c1-25(23(28)22-18-8-3-6-11-21(18)30-24-22)12-7-13-26-14-16-27(17-15-26)19-9-4-5-10-20(19)29-2/h3-6,8-11H,7,12-17H2,1-2H3 NXHJZSQUERIEOI-UHFFFAOYSA-N 50036901 Benzo[d]isothiazole-3-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-methyl-amide::CHEMBL76110 D(2) dopamine receptor Rattus norvegicus 541 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036901&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10342321 103944542 CHEMBL76110 ZINC13737871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057472 Clc1ccc2c(noc2c1)C1CCN(CCCNC(=O)c2nsc3ccccc23)CC1 InChI=1S/C23H23ClN4O2S/c24-16-6-7-17-19(14-16)30-26-21(17)15-8-12-28(13-9-15)11-3-10-25-23(29)22-18-4-1-2-5-20(18)31-27-22/h1-2,4-7,14-15H,3,8-13H2,(H,25,29) TZNZWIRUAXXIMC-UHFFFAOYSA-N 50036906 Benzo[d]isothiazole-3-carboxylic acid {3-[4-(6-chloro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propyl}-amide::CHEMBL77049 D(2) dopamine receptor Rattus norvegicus 739.1 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036906&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10434143 103944547 CHEMBL77049 ZINC13737873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057484 Fc1ccc2c(csc2c1)N1CCN(CCNC(=O)c2noc3ccccc23)CC1 InChI=1S/C22H21FN4O2S/c23-15-5-6-16-18(14-30-20(16)13-15)27-11-9-26(10-12-27)8-7-24-22(28)21-17-3-1-2-4-19(17)29-25-21/h1-6,13-14H,7-12H2,(H,24,28) CUAXKVLQJDIYRA-UHFFFAOYSA-N 50036882 Benzo[d]isoxazole-3-carboxylic acid {2-[4-(6-fluoro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-ethyl}-amide::CHEMBL73792 D(2) dopamine receptor Rattus norvegicus 1368.7 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036882&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11743091 103944523 CHEMBL73792 ZINC26380359 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057486 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1nsc2ccccc12 InChI=1S/C23H25N5OS2/c29-23(21-17-7-1-3-9-19(17)30-25-21)24-11-5-6-12-27-13-15-28(16-14-27)22-18-8-2-4-10-20(18)31-26-22/h1-4,7-10H,5-6,11-16H2,(H,24,29) BVKLJQKPEWBBEW-UHFFFAOYSA-N 50036900 Benzo[d]isothiazole-3-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide::CHEMBL305866 D(2) dopamine receptor Rattus norvegicus 360 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036900&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3073070 103944541 CHEMBL305866 ZINC01555090 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057494 CN(CCCCN1CCN(CC1)c1csc2cc(F)ccc12)C(=O)c1nsc2ccccc12 InChI=1S/C25H27FN4OS2/c1-28(25(31)24-20-6-2-3-7-22(20)33-27-24)10-4-5-11-29-12-14-30(15-13-29)21-17-32-23-16-18(26)8-9-19(21)23/h2-3,6-9,16-17H,4-5,10-15H2,1H3 MPZIBOGLQLOZET-UHFFFAOYSA-N 50036890 Benzo[d]isothiazole-3-carboxylic acid {4-[4-(6-fluoro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-methyl-amide::CHEMBL76461 D(2) dopamine receptor Rattus norvegicus 671.0 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9869884 103944531 CHEMBL76461 ZINC13737872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057498 CN(CCCCN1CCC(CC1)C(=O)c1ccc(F)cc1)C(=O)c1nsc2ccccc12 InChI=1S/C25H28FN3O2S/c1-28(25(31)23-21-6-2-3-7-22(21)32-27-23)14-4-5-15-29-16-12-19(13-17-29)24(30)18-8-10-20(26)11-9-18/h2-3,6-11,19H,4-5,12-17H2,1H3 NHELSUKECDTJIG-UHFFFAOYSA-N 50036909 Benzo[d]isothiazole-3-carboxylic acid {4-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-butyl}-methyl-amide::CHEMBL73430 D(2) dopamine receptor Rattus norvegicus 245.6 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036909&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11744655 103944550 CHEMBL73430 ZINC13737878 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057500 CN(CCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)c1nsc2ccccc12 InChI=1S/C25H27FN4O2S/c1-29(25(31)24-20-6-2-3-7-22(20)33-28-24)12-4-5-13-30-14-10-17(11-15-30)23-19-9-8-18(26)16-21(19)32-27-23/h2-3,6-9,16-17H,4-5,10-15H2,1H3 RRJGHQGFXIURME-UHFFFAOYSA-N 50036902 Benzo[d]isothiazole-3-carboxylic acid {4-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-butyl}-methyl-amide::CHEMBL310261 D(2) dopamine receptor Rattus norvegicus 72.6 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036902&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10253984 103944543 CHEMBL310261 ZINC13737886 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057502 COc1ccccc1N1CCN(CCCNC(=O)c2nsc3ccccc23)CC1 InChI=1S/C22H26N4O2S/c1-28-19-9-4-3-8-18(19)26-15-13-25(14-16-26)12-6-11-23-22(27)21-17-7-2-5-10-20(17)29-24-21/h2-5,7-10H,6,11-16H2,1H3,(H,23,27) MQPHIJKZERHYFD-UHFFFAOYSA-N 50036898 Benzo[d]isothiazole-3-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL75582 D(2) dopamine receptor Rattus norvegicus 193 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036898&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10001614 103944539 CHEMBL75582 ZINC12356311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057506 CN1CCN(CCNC(=O)c2nsc3ccccc23)CC1 InChI=1S/C15H20N4OS/c1-18-8-10-19(11-9-18)7-6-16-15(20)14-12-4-2-3-5-13(12)21-17-14/h2-5H,6-11H2,1H3,(H,16,20) WMXVMIIWAHJNQR-UHFFFAOYSA-N 50036896 Benzo[d]isothiazole-3-carboxylic acid [2-(4-methyl-piperazin-1-yl)-ethyl]-amide::CHEMBL306134 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036896&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357692 103944537 CHEMBL306134 ZINC22937387 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057515 O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1nsc2ccccc12 InChI=1S/C22H23N5O2S/c28-21(20-16-5-1-4-8-19(16)30-25-20)23-11-14-26-12-9-15(10-13-26)27-18-7-3-2-6-17(18)24-22(27)29/h1-8,15H,9-14H2,(H,23,28)(H,24,29) MZSPDUGCCTYLQZ-UHFFFAOYSA-N 50036883 Benzo[d]isothiazole-3-carboxylic acid {2-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-ethyl}-amide::CHEMBL431000 D(2) dopamine receptor Rattus norvegicus 5589 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036883&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10364885 103944524 CHEMBL431000 ZINC00605469 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057517 CC(C)N(CCCN1CCC(CC1)C(=O)c1ccc(F)cc1)C(=O)c1noc2ccccc12 InChI=1S/C26H30FN3O3/c1-18(2)30(26(32)24-22-6-3-4-7-23(22)33-28-24)15-5-14-29-16-12-20(13-17-29)25(31)19-8-10-21(27)11-9-19/h3-4,6-11,18,20H,5,12-17H2,1-2H3 GVJMXEUUBIGHPA-UHFFFAOYSA-N 50036891 Benzo[d]isoxazole-3-carboxylic acid {3-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-propyl}-isopropyl-amide::CHEMBL78330 D(2) dopamine receptor Rattus norvegicus 804.2 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036891&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10433964 103944532 CHEMBL78330 ZINC13737879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057518 CN(CCCN1CCC(CC1)C(=O)c1ccc(F)cc1)C(=O)c1nsc2ccccc12 InChI=1S/C24H26FN3O2S/c1-27(24(30)22-20-5-2-3-6-21(20)31-26-22)13-4-14-28-15-11-18(12-16-28)23(29)17-7-9-19(25)10-8-17/h2-3,5-10,18H,4,11-16H2,1H3 WSWFAZIJVIGXBX-UHFFFAOYSA-N 50036907 Benzo[d]isothiazole-3-carboxylic acid {3-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-propyl}-methyl-amide::CHEMBL75653 D(2) dopamine receptor Rattus norvegicus 716.6 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10003321 103944548 CHEMBL75653 ZINC13737881 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057521 CN(CCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)c1nsc2ccccc12 InChI=1S/C23H23FN4O2S/c1-27(23(29)22-18-4-2-3-5-20(18)31-26-22)12-13-28-10-8-15(9-11-28)21-17-7-6-16(24)14-19(17)30-25-21/h2-7,14-15H,8-13H2,1H3 HWKDDIYQGMIJRT-UHFFFAOYSA-N 50036899 Benzo[d]isothiazole-3-carboxylic acid {2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-methyl-amide::CHEMBL74892 D(2) dopamine receptor Rattus norvegicus 264 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036899&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10433258 103944540 CHEMBL74892 ZINC13737884 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057523 COc1ccccc1N1CCN(CCNC(=O)c2noc3ccccc23)CC1 InChI=1S/C21H24N4O3/c1-27-19-9-5-3-7-17(19)25-14-12-24(13-15-25)11-10-22-21(26)20-16-6-2-4-8-18(16)28-23-20/h2-9H,10-15H2,1H3,(H,22,26) ZPEOMOBNWFUZJX-UHFFFAOYSA-N 50036884 Benzo[d]isoxazole-3-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL75431 D(2) dopamine receptor Rattus norvegicus 473 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11740508 103944525 CHEMBL75431 ZINC13737870 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057526 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 32.7 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056437 CCCN1CC[C@@H]2[C@H]1CCc1cccc(C(=O)NCc3ccccc3)c21 InChI=1S/C23H28N2O/c1-2-14-25-15-13-19-21(25)12-11-18-9-6-10-20(22(18)19)23(26)24-16-17-7-4-3-5-8-17/h3-10,19,21H,2,11-16H2,1H3,(H,24,26)/t19-,21-/m1/s1 WODGNNDXZXXSSM-TZIWHRDSSA-N 50036446 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid benzylamide::CHEMBL351857 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9997912 103944211 CHEMBL351857 ZINC13740527 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056438 CC(C)=CCN1CC[C@@H]2[C@H]1CCc1cccc(C(N)=O)c21 InChI=1S/C18H24N2O/c1-12(2)8-10-20-11-9-14-16(20)7-6-13-4-3-5-15(17(13)14)18(19)21/h3-5,8,14,16H,6-7,9-11H2,1-2H3,(H2,19,21)/t14-,16-/m1/s1 NDRQLZDJEAYQFH-GDBMZVCRSA-N 50036448 (3aR,9bS)-3-(3-Methyl-but-2-enyl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL355601 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036448&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15196980 103944213 CHEMBL355601 ZINC13740522 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056441 Brc1cccc2CC[C@@H]3[C@@H](CCN3CC3CC3)c12 InChI=1S/C16H20BrN/c17-14-3-1-2-12-6-7-15-13(16(12)14)8-9-18(15)10-11-4-5-11/h1-3,11,13,15H,4-10H2/t13-,15-/m1/s1 HSTCPLNDACKSGT-UKRRQHHQSA-N 50036450 (3aR,9bS)-9-Bromo-3-cyclopropylmethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL163134 D(2) dopamine receptor Rattus norvegicus 119 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036450&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357784 103944215 CHEMBL163134 ZINC12355942 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056442 NC(=O)c1cccc2CC[C@@H]3[C@@H](CCN3CCC=C)c12 InChI=1S/C17H22N2O/c1-2-3-10-19-11-9-13-15(19)8-7-12-5-4-6-14(16(12)13)17(18)20/h2,4-6,13,15H,1,3,7-11H2,(H2,18,20)/t13-,15-/m1/s1 KSBJKEDRSNWDGV-UKRRQHHQSA-N 50036451 (3aR,9bS)-3-But-3-enyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL159886 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036451&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015984 103944216 CHEMBL159886 ZINC13740518 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056443 Brc1cccc2CC[C@@H]3[C@@H](CCN3CCC=C)c12 InChI=1S/C16H20BrN/c1-2-3-10-18-11-9-13-15(18)8-7-12-5-4-6-14(17)16(12)13/h2,4-6,13,15H,1,3,7-11H2/t13-,15-/m1/s1 FPHSAPRRIZSVDD-UKRRQHHQSA-N 50036453 (3aR,9bS)-9-Bromo-3-but-3-enyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL423612 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425232 103944218 CHEMBL423612 ZINC13740508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056446 ClCCCN1CC[C@@H]2[C@H]1CCc1cccc(Br)c21 InChI=1S/C15H19BrClN/c16-13-4-1-3-11-5-6-14-12(15(11)13)7-10-18(14)9-2-8-17/h1,3-4,12,14H,2,5-10H2/t12-,14-/m1/s1 HTRITDVQTYLHKC-TZMCWYRMSA-N 50036455 (3aR,9bS)-9-Bromo-3-(3-chloro-propyl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL421839 D(2) dopamine receptor Rattus norvegicus 73 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036455&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10336649 103944220 CHEMBL421839 ZINC13740511 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056448 COCCN1CC[C@@H]2[C@H]1CCc1cccc(Br)c21 InChI=1S/C15H20BrNO/c1-18-10-9-17-8-7-12-14(17)6-5-11-3-2-4-13(16)15(11)12/h2-4,12,14H,5-10H2,1H3/t12-,14-/m1/s1 RXNMHOXFFXCXMM-TZMCWYRMSA-N 50036457 (3aR,9bS)-9-Bromo-3-(2-methoxy-ethyl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL350145 D(2) dopamine receptor Rattus norvegicus 252 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10380664 103944222 CHEMBL350145 ZINC13740509 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056449 NC(=O)c1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C16H20N2O/c1-2-9-18-10-8-12-14(18)7-6-11-4-3-5-13(15(11)12)16(17)19/h2-5,12,14H,1,6-10H2,(H2,17,19)/t12-,14-/m1/s1 LEIMRNZHCBXFFR-TZMCWYRMSA-N 50036458 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL161890 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11777188 103944223 CHEMBL161890 ZINC13740515 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056452 CCN1CC[C@@H]2[C@H]1CCc1cccc(Br)c21 InChI=1S/C14H18BrN/c1-2-16-9-8-11-13(16)7-6-10-4-3-5-12(15)14(10)11/h3-5,11,13H,2,6-9H2,1H3/t11-,13-/m1/s1 VEWQTYIHSDLEIL-DGCLKSJQSA-N 50036449 (3aR,9bS)-9-Bromo-3-ethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL161940 D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036449&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10423762 103944214 CHEMBL161940 ZINC13740505 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056457 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056459 COCCN1CC[C@@H]2[C@H]1CCc1cccc(C(N)=O)c21 InChI=1S/C16H22N2O2/c1-20-10-9-18-8-7-12-14(18)6-5-11-3-2-4-13(15(11)12)16(17)19/h2-4,12,14H,5-10H2,1H3,(H2,17,19)/t12-,14-/m1/s1 FMXNGDVMAZRBJO-TZMCWYRMSA-N 50036456 (3aR,9bS)-3-(2-Methoxy-ethyl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL163258 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10016190 103944221 CHEMBL163258 ZINC13740519 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056460 CCCCN1CC[C@@H]2[C@H]1CCc1cccc(C(N)=O)c21 InChI=1S/C17H24N2O/c1-2-3-10-19-11-9-13-15(19)8-7-12-5-4-6-14(16(12)13)17(18)20/h4-6,13,15H,2-3,7-11H2,1H3,(H2,18,20)/t13-,15-/m1/s1 HSPQOFOFQPRHNO-UKRRQHHQSA-N 50036462 (3aR,9bS)-3-Butyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL162035 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9970485 103944227 CHEMBL162035 ZINC13740516 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056461 CCN1CC[C@@H]2[C@H]1CCc1cccc(C(N)=O)c21 InChI=1S/C15H20N2O/c1-2-17-9-8-11-13(17)7-6-10-4-3-5-12(14(10)11)15(16)18/h3-5,11,13H,2,6-9H2,1H3,(H2,16,18)/t11-,13-/m1/s1 DZUXYVDMWRUWQY-DGCLKSJQSA-N 50036463 (3aR,9bS)-3-Ethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL352887 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036463&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10243556 103944228 CHEMBL352887 ZINC13740514 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056462 CC(C)=CCN1CC[C@@H]2[C@H]1CCc1cccc(Br)c21 InChI=1S/C17H22BrN/c1-12(2)8-10-19-11-9-14-16(19)7-6-13-4-3-5-15(18)17(13)14/h3-5,8,14,16H,6-7,9-11H2,1-2H3/t14-,16-/m1/s1 HOMGCJQPMMXIQO-GDBMZVCRSA-N 50036465 (3aR,9bS)-9-Bromo-3-(3-methyl-but-2-enyl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL163469 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9973280 103944230 CHEMBL163469 ZINC13740512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056464 NC(=O)c1cccc2CC[C@@H]3[C@@H](CCN3CC3CC3)c12 InChI=1S/C17H22N2O/c18-17(20)14-3-1-2-12-6-7-15-13(16(12)14)8-9-19(15)10-11-4-5-11/h1-3,11,13,15H,4-10H2,(H2,18,20)/t13-,15-/m1/s1 JXYMYIOBDAVBFP-UKRRQHHQSA-N 50036464 (3aR,9bS)-3-Cyclopropylmethyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL349502 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036464&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11777934 103944229 CHEMBL349502 ZINC13740517 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056465 CCCN1CC[C@@H]2[C@H]1CCc1cccc(C(=O)NCC=C)c21 InChI=1S/C19H26N2O/c1-3-11-20-19(22)16-7-5-6-14-8-9-17-15(18(14)16)10-13-21(17)12-4-2/h3,5-7,15,17H,1,4,8-13H2,2H3,(H,20,22)/t15-,17-/m1/s1 BFWXRKAZGSGLJZ-NVXWUHKLSA-N 50036445 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid allylamide::CHEMBL159625 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9971925 103944210 CHEMBL159625 ZINC13740526 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056466 CCCN1CC[C@@H]2[C@H]1CCc1cccc(C(C)=O)c21 InChI=1S/C17H23NO/c1-3-10-18-11-9-15-16(18)8-7-13-5-4-6-14(12(2)19)17(13)15/h4-6,15-16H,3,7-11H2,1-2H3/t15-,16-/m1/s1 PMSNWAIFNUHOQD-HZPDHXFCSA-N 50036452 1-((3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-yl)-ethanone::CHEMBL351234 D(2) dopamine receptor Rattus norvegicus 91 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036452&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377778 103944217 CHEMBL351234 ZINC13740529 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056467 CCCNC(=O)c1cccc2CC[C@@H]3[C@@H](CCN3CCC)c12 InChI=1S/C19H28N2O/c1-3-11-20-19(22)16-7-5-6-14-8-9-17-15(18(14)16)10-13-21(17)12-4-2/h5-7,15,17H,3-4,8-13H2,1-2H3,(H,20,22)/t15-,17-/m1/s1 ONKLJYZLUGVESH-NVXWUHKLSA-N 50036467 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid propylamide::CHEMBL162227 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10266826 103944232 CHEMBL162227 ZINC13740525 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056468 CC(C)CN1CC[C@@H]2[C@H]1CCc1cccc(C(N)=O)c21 InChI=1S/C17H24N2O/c1-11(2)10-19-9-8-13-15(19)7-6-12-4-3-5-14(16(12)13)17(18)20/h3-5,11,13,15H,6-10H2,1-2H3,(H2,18,20)/t13-,15-/m1/s1 MHDYVLNVEGHSGG-UKRRQHHQSA-N 50036460 (3aR,9bS)-3-Isobutyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL160040 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036460&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10423393 103944225 CHEMBL160040 ZINC13740523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056471 CCCN1CC[C@@H]2[C@H]1CCc1cccc(C(=O)CCC)c21 InChI=1S/C19H27NO/c1-3-6-18(21)16-8-5-7-14-9-10-17-15(19(14)16)11-13-20(17)12-4-2/h5,7-8,15,17H,3-4,6,9-13H2,1-2H3/t15-,17-/m1/s1 CDPZOLAASNARLZ-NVXWUHKLSA-N 50036459 1-((3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-yl)-butan-1-one::CHEMBL349604 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10469194 103944224 CHEMBL349604 ZINC13740530 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056472 FCCCN1CC[C@@H]2[C@H]1CCc1cccc(Br)c21 InChI=1S/C15H19BrFN/c16-13-4-1-3-11-5-6-14-12(15(11)13)7-10-18(14)9-2-8-17/h1,3-4,12,14H,2,5-10H2/t12-,14-/m1/s1 RZBVNNAVUAHSRN-TZMCWYRMSA-N 50036468 (3aR,9bS)-9-Bromo-3-(3-fluoro-propyl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL354455 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10335665 103944233 CHEMBL354455 ZINC13740510 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056473 NC(=O)c1cccc2CC[C@@H]3[C@@H](CCN3CCCF)c12 InChI=1S/C16H21FN2O/c17-8-2-9-19-10-7-12-14(19)6-5-11-3-1-4-13(15(11)12)16(18)20/h1,3-4,12,14H,2,5-10H2,(H2,18,20)/t12-,14-/m1/s1 GGENIZGCFCBFDF-TZMCWYRMSA-N 50036471 (3aR,9bS)-3-(3-Fluoro-propyl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL161904 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10468696 103944236 CHEMBL161904 ZINC13740520 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056475 CCCN1CC[C@@H]2[C@H]1CCc1cccc(C(=O)C(C)C)c21 InChI=1S/C19H27NO/c1-4-11-20-12-10-15-17(20)9-8-14-6-5-7-16(18(14)15)19(21)13(2)3/h5-7,13,15,17H,4,8-12H2,1-3H3/t15-,17-/m1/s1 FXKWSBLKVYEGAY-NVXWUHKLSA-N 50036454 2-Methyl-1-((3aR,9bS)-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-yl)-propan-1-one::CHEMBL421848 D(2) dopamine receptor Rattus norvegicus 62 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036454&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10379212 103944219 CHEMBL421848 ZINC13740531 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056480 CCCN(CCC)C(=O)c1cccc2CC[C@@H]3[C@@H](CCN3CCC)c12 InChI=1S/C22H34N2O/c1-4-13-23-16-12-18-20(23)11-10-17-8-7-9-19(21(17)18)22(25)24(14-5-2)15-6-3/h7-9,18,20H,4-6,10-16H2,1-3H3/t18-,20-/m1/s1 BIWNMNHJFZWZIO-UYAOXDASSA-N 50036461 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid dipropylamide::CHEMBL163619 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036461&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10405139 103944226 CHEMBL163619 ZINC13740528 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056482 CN1CC[C@@H]2[C@H]1CCc1cccc(Br)c21 InChI=1S/C13H16BrN/c1-15-8-7-10-12(15)6-5-9-3-2-4-11(14)13(9)10/h2-4,10,12H,5-8H2,1H3/t10-,12-/m1/s1 ZAOMCAZYWCQAGK-ZYHUDNBSSA-N 50036447 (3aR,9bS)-9-Bromo-3-methyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL161891 D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10061422 103944212 CHEMBL161891 ZINC13740504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056483 CN1CC[C@@H]2[C@H]1CCc1cccc(C(N)=O)c21 InChI=1S/C14H18N2O/c1-16-8-7-10-12(16)6-5-9-3-2-4-11(13(9)10)14(15)17/h2-4,10,12H,5-8H2,1H3,(H2,15,17)/t10-,12-/m1/s1 OEHRTTDNZXEQFL-ZYHUDNBSSA-N 50036466 (3aR,9bS)-3-Methyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL163135 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10421389 103944231 CHEMBL163135 ZINC13740513 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056487 Brc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C15H18BrN/c1-2-9-17-10-8-12-14(17)7-6-11-4-3-5-13(16)15(11)12/h2-5,12,14H,1,6-10H2/t12-,14-/m1/s1 ACZSQSNJZPULJH-TZMCWYRMSA-N 50036469 (3aR,9bS)-3-Allyl-9-bromo-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL164195 D(2) dopamine receptor Rattus norvegicus 3.2 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036469&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10424408 103944234 CHEMBL164195 ZINC13740506 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057534 COc1ccccc1N1CCN(CCCCN(C)C(=O)c2nsc3ccccc23)CC1 InChI=1S/C24H30N4O2S/c1-26(24(29)23-19-9-3-6-12-22(19)31-25-23)13-7-8-14-27-15-17-28(18-16-27)20-10-4-5-11-21(20)30-2/h3-6,9-12H,7-8,13-18H2,1-2H3 SFRDJPWNPXRKGC-UHFFFAOYSA-N 50036893 Benzo[d]isothiazole-3-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-methyl-amide::CHEMBL309811 D(2) dopamine receptor Rattus norvegicus 136 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036893&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10003265 103944534 CHEMBL309811 ZINC13737869 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057546 CN(CCN1CCC(CC1)C(=O)c1ccc(F)cc1)C(=O)c1noc2ccccc12 InChI=1S/C23H24FN3O3/c1-26(23(29)21-19-4-2-3-5-20(19)30-25-21)14-15-27-12-10-17(11-13-27)22(28)16-6-8-18(24)9-7-16/h2-9,17H,10-15H2,1H3 HINBYTOQYDZMEP-UHFFFAOYSA-N 50036905 Benzo[d]isoxazole-3-carboxylic acid {2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-ethyl}-methyl-amide::CHEMBL78159 D(2) dopamine receptor Rattus norvegicus 584 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036905&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10409240 103944546 CHEMBL78159 ZINC13737880 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057549 Clc1cccc(c1)N1CCN(CCNC(=O)c2nsc3ccccc23)CC1 InChI=1S/C20H21ClN4OS/c21-15-4-3-5-16(14-15)25-12-10-24(11-13-25)9-8-22-20(26)19-17-6-1-2-7-18(17)27-23-19/h1-7,14H,8-13H2,(H,22,26) XXTACOMMLAVRLZ-UHFFFAOYSA-N 50036908 Benzo[d]isothiazole-3-carboxylic acid {2-[4-(3-chloro-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL424235 D(2) dopamine receptor Rattus norvegicus 3191 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036908&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11741747 103944549 CHEMBL424235 ZINC13737876 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057527 O=C(NCCN1CCN(CC1)c1nsc2ccccc12)c1nsc2ccccc12 InChI=1S/C21H21N5OS2/c27-21(19-15-5-1-3-7-17(15)28-23-19)22-9-10-25-11-13-26(14-12-25)20-16-6-2-4-8-18(16)29-24-20/h1-8H,9-14H2,(H,22,27) RDWHXTXGJUIKOG-UHFFFAOYSA-N 50036903 Benzo[d]isothiazole-3-carboxylic acid [2-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-amide::CHEMBL72987 D(2) dopamine receptor Rattus norvegicus 169 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036903&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025331 103944544 CHEMBL72987 ZINC12356313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057529 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 37 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057596 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Rattus norvegicus 1250 ChEMBL 10.1021/jm00041a025 10.7270/Q2KS6QKD 7914538 Knoerzer, TA; Nichols, DE; Brewster, WK; Watts, VJ; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057601 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 2.8 ChEMBL 10.1021/jm00041a025 10.7270/Q2KS6QKD 7914538 Knoerzer, TA; Nichols, DE; Brewster, WK; Watts, VJ; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054324 CCCN(CCC)C1CCc2cc(F)c3[nH]cc(C(=O)CC)c3c2C1 InChI=1S/C21H29FN2O/c1-4-9-24(10-5-2)15-8-7-14-11-18(22)21-20(16(14)12-15)17(13-23-21)19(25)6-3/h11,13,15,23H,4-10,12H2,1-3H3 UTKHSRGDDNRWQN-UHFFFAOYSA-N 50035300 1-(8-Dipropylamino-4-fluoro-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-propan-1-one::CHEMBL70985 D(2) dopamine receptor Rattus norvegicus 377 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035300&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10360150 103943326 CHEMBL70985 ZINC13741699 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054326 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 1126 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054330 CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m0/s1 DSEPKSLFXGYPIU-INIZCTEOSA-N 50035305 (S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL307786 D(2) dopamine receptor Rattus norvegicus 423.0 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035305&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948210 103943331 CHEMBL307786 ZINC00005554 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054343 CCCN(CCC)C1CCc2ccc3[nH]cc(C(=O)c4ccccc4)c3c2C1 InChI=1S/C25H30N2O/c1-3-14-27(15-4-2)20-12-10-18-11-13-23-24(21(18)16-20)22(17-26-23)25(28)19-8-6-5-7-9-19/h5-9,11,13,17,20,26H,3-4,10,12,14-16H2,1-2H3 WYHYLXRVYVASMT-UHFFFAOYSA-N 50035316 (8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-phenyl-methanone::CHEMBL302994 D(2) dopamine receptor Rattus norvegicus 177 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035316&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10407084 103943342 CHEMBL302994 ZINC13741711 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054362 CCCN(CCC)C1CCc2ccc3[nH]cc(c3c2C1)S(C)(=O)=O InChI=1S/C19H28N2O2S/c1-4-10-21(11-5-2)15-8-6-14-7-9-17-19(16(14)12-15)18(13-20-17)24(3,22)23/h7,9,13,15,20H,4-6,8,10-12H2,1-3H3 WXMITIKKXMDVPX-UHFFFAOYSA-N 50035309 (1-Methanesulfonyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL303269 D(2) dopamine receptor Rattus norvegicus 265 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035309&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11725335 103943335 CHEMBL303269 ZINC13741727 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054365 CCCN(CCC)[C@H]1CCc2cc(F)c3[nH]cc(C=O)c3c2C1 InChI=1S/C19H25FN2O/c1-3-7-22(8-4-2)15-6-5-13-9-17(20)19-18(16(13)10-15)14(12-23)11-21-19/h9,11-12,15,21H,3-8,10H2,1-2H3/t15-/m0/s1 ICOOOYKBBQSJND-HNNXBMFYSA-N 50035315 (S)-8-Dipropylamino-4-fluoro-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL70652 D(2) dopamine receptor Rattus norvegicus 199 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035315&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10064361 103943341 CHEMBL70652 ZINC13741695 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054371 CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1 GKDJCOLVXBCNNK-OAHLLOKOSA-N 50035330 CHEMBL302172::Dipropyl-(R)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::R-(+)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 7.4 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10858566 103943356 CHEMBL302172 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054372 CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C#N)c3c2C1 InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3/t16-/m1/s1 ODCNQSRYNGLVNW-MRXNPFEDSA-N 50035328 (R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbonitrile::CHEMBL308347 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035328&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10402263 103943354 CHEMBL308347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054376 CCCN(CCC)C1CCc2ccc3[nH]cc(C)c3c2C1 InChI=1S/C19H28N2/c1-4-10-21(11-5-2)16-8-6-15-7-9-18-19(17(15)12-16)14(3)13-20-18/h7,9,13,16,20H,4-6,8,10-12H2,1-3H3 BLMNALZUWKHXKM-UHFFFAOYSA-N 50035310 (1-Methyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL69562 D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035310&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10356544 103943336 CHEMBL69562 ZINC13741721 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054378 CCCN(CCC)C1CCc2ccc3[nH]cc(C(=O)C(F)(F)F)c3c2C1 InChI=1S/C20H25F3N2O/c1-3-9-25(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(12-24-17)19(26)20(21,22)23/h6,8,12,14,24H,3-5,7,9-11H2,1-2H3 FNUVHMFBVOHLQV-UHFFFAOYSA-N 50035302 1-(8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-2,2,2-trifluoro-ethanone::CHEMBL302263 D(2) dopamine receptor Rattus norvegicus 544 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035302&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11726413 103943328 CHEMBL302263 ZINC13741707 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054379 CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3 GKDJCOLVXBCNNK-UHFFFAOYSA-N 50035329 (+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine::CHEMBL65196::Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035329&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13096730 103943355 CHEMBL65196 ZINC03798326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054380 CCCN(CCC)C1CCc2c(C1)ccc(F)c2N InChI=1S/C16H25FN2/c1-3-9-19(10-4-2)13-6-7-14-12(11-13)5-8-15(17)16(14)18/h5,8,13H,3-4,6-7,9-11,18H2,1-2H3 GBMSGSHLNWAQNZ-UHFFFAOYSA-N 50035332 2-Fluoro-N*6*,N*6*-dipropyl-5,6,7,8-tetrahydro-naphthalene-1,6-diamine::CHEMBL71676 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035332&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44310169 103943358 CHEMBL71676 ZINC26283307 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054381 CCCN(CCC)C1CCc2ccc3n(C)cc(C=O)c3c2C1 InChI=1S/C20H28N2O/c1-4-10-22(11-5-2)17-8-6-15-7-9-19-20(18(15)12-17)16(14-23)13-21(19)3/h7,9,13-14,17H,4-6,8,10-12H2,1-3H3 WZFMGRURRVAGFE-UHFFFAOYSA-N 50035323 8-Dipropylamino-3-methyl-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL71299 D(2) dopamine receptor Rattus norvegicus 510 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10403260 103943349 CHEMBL71299 ZINC13741723 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054386 CCCN(CCC)C1CCc2cc(F)c3[nH]ccc3c2C1 InChI=1S/C18H25FN2/c1-3-9-21(10-4-2)14-6-5-13-11-17(19)18-15(7-8-20-18)16(13)12-14/h7-8,11,14,20H,3-6,9-10,12H2,1-2H3 YCTBHVBIEDZWCH-UHFFFAOYSA-N 50035304 (4-Fluoro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL305743 D(2) dopamine receptor Rattus norvegicus 2.8 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035304&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10424220 103943330 CHEMBL305743 ZINC13741692 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056494 NC(=O)c1cccc2CC[C@@H]3[C@@H](CCN3CCCCl)c12 InChI=1S/C16H21ClN2O/c17-8-2-9-19-10-7-12-14(19)6-5-11-3-1-4-13(15(11)12)16(18)20/h1,3-4,12,14H,2,5-10H2,(H2,18,20)/t12-,14-/m1/s1 GEBJBFHSEJGFDJ-TZMCWYRMSA-N 50036473 (3aR,9bS)-3-(3-Chloro-propyl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL441486 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11779143 103944238 CHEMBL441486 ZINC13740521 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056495 NC(=O)c1cccc2CC[C@@H]3[C@@H](CCN3CC#C)c12 InChI=1S/C16H18N2O/c1-2-9-18-10-8-12-14(18)7-6-11-4-3-5-13(15(11)12)16(17)19/h1,3-5,12,14H,6-10H2,(H2,17,19)/t12-,14-/m1/s1 XHVMTLOXBRVJSM-TZMCWYRMSA-N 50036472 (3aR,9bS)-3-Prop-2-ynyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL162167 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11777090 103944237 CHEMBL162167 ZINC13740524 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056496 CCCCN1CC[C@@H]2[C@H]1CCc1cccc(Br)c21 InChI=1S/C16H22BrN/c1-2-3-10-18-11-9-13-15(18)8-7-12-5-4-6-14(17)16(12)13/h4-6,13,15H,2-3,7-11H2,1H3/t13-,15-/m1/s1 BRQVGMJTCISYCF-UKRRQHHQSA-N 50036474 (3aR,9bS)-9-Bromo-3-butyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL162767 D(2) dopamine receptor Rattus norvegicus 75 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086570 103944239 CHEMBL162767 ZINC13740507 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056491 CCCN1CC[C@@H]2[C@H]1CCc1cccc(C(N)=O)c21 InChI=1S/C16H22N2O/c1-2-9-18-10-8-12-14(18)7-6-11-4-3-5-13(15(11)12)16(17)19/h3-5,12,14H,2,6-10H2,1H3,(H2,17,19)/t12-,14-/m1/s1 JSZBRMZCAIJCKB-TZMCWYRMSA-N 50036470 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-9-carboxylic acid amide::CHEMBL349003 D(2) dopamine receptor Rattus norvegicus >1629 ChEMBL 10.1021/jm00004a018 10.7270/Q20Z72B7 7861420 Haadsma-Svensson, SR; Svensson, K; Duncan, N; Smith, MW; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 132792 103944235 CHEMBL349003 ZINC00005617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057609 O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C23H24N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h1-4,7-10H,5-6,11-16H2 YKKGANFNJXSMSN-UHFFFAOYSA-N 50036918 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-isoindole-1,3-dione::CHEMBL290937 D(2) dopamine receptor Rattus norvegicus 49 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10093606 103944559 CHEMBL290937 ZINC02010593 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057612 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 290 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057619 O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 InChI=1S/C23H26N4OS/c28-23-19-8-2-1-7-18(19)17-27(23)12-6-5-11-25-13-15-26(16-14-25)22-20-9-3-4-10-21(20)29-24-22/h1-4,7-10H,5-6,11-17H2 ZPAUMFOJNAADJN-UHFFFAOYSA-N 50036922 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2,3-dihydro-isoindol-1-one::CHEMBL41626 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036922&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10046952 103944563 CHEMBL41626 ZINC01537574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057621 Cc1nn(CCCCN2CCN(CC2)c2nsc3ccccc23)c(=O)c2ccccc12 InChI=1S/C24H27N5OS/c1-18-19-8-2-3-9-20(19)24(30)29(25-18)13-7-6-12-27-14-16-28(17-15-27)23-21-10-4-5-11-22(21)31-26-23/h2-5,8-11H,6-7,12-17H2,1H3 MVSWAPHZZRDVCH-UHFFFAOYSA-N 50036923 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4-methyl-2H-phthalazin-1-one::CHEMBL83195 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10252320 103944564 CHEMBL83195 ZINC13738134 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057624 O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)CCCc2ccccc12 InChI=1S/C25H30N4OS/c30-25-21-10-2-1-8-20(21)9-7-15-29(25)14-6-5-13-27-16-18-28(19-17-27)24-22-11-3-4-12-23(22)31-26-24/h1-4,8,10-12H,5-7,9,13-19H2 XITOBPDXYLJVKL-UHFFFAOYSA-N 50036927 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2,3,4,5-tetrahydro-benzo[c]azepin-1-one::CHEMBL315925 D(2) dopamine receptor Rattus norvegicus 5.2 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036927&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10320742 103944568 CHEMBL315925 ZINC12356425 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057629 O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)S(=O)(=O)c2ccccc12 InChI=1S/C22H24N4O3S2/c27-22-18-8-2-4-10-20(18)31(28,29)26(22)12-6-5-11-24-13-15-25(16-14-24)21-17-7-1-3-9-19(17)30-23-21/h1-4,7-10H,5-6,11-16H2 UGVNGMAVECELKC-UHFFFAOYSA-N 50036928 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one::CHEMBL87294 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036928&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14096630 103944569 CHEMBL87294 ZINC01551142 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057630 O=c1[nH]n(CCCCN2CCN(CC2)c2nsc3ccccc23)c(=O)c2ccccc12 InChI=1S/C23H25N5O2S/c29-22-17-7-1-2-8-18(17)23(30)28(24-22)12-6-5-11-26-13-15-27(16-14-26)21-19-9-3-4-10-20(19)31-25-21/h1-4,7-10H,5-6,11-16H2,(H,24,29) FNQIJCGHUHTWLH-UHFFFAOYSA-N 50036930 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2,3-dihydro-phthalazine-1,4-dione::CHEMBL85137 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10048606 103944571 CHEMBL85137 ZINC13738138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057632 O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)CCc2ccccc12 InChI=1S/C24H28N4OS/c29-24-20-8-2-1-7-19(20)11-14-28(24)13-6-5-12-26-15-17-27(18-16-26)23-21-9-3-4-10-22(21)30-25-23/h1-4,7-10H,5-6,11-18H2 XUBYSOXUXGRFJY-UHFFFAOYSA-N 50036919 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3,4-dihydro-2H-isoquinolin-1-one::CHEMBL86013 D(2) dopamine receptor Rattus norvegicus 5.8 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036919&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10002242 103944560 CHEMBL86013 ZINC01537576 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057636 O=C1C2CCCCC2C=NN1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H31N5OS/c29-23-19-8-2-1-7-18(19)17-24-28(23)12-6-5-11-26-13-15-27(16-14-26)22-20-9-3-4-10-21(20)30-25-22/h3-4,9-10,17-19H,1-2,5-8,11-16H2 BBONTYVGVUFBBF-UHFFFAOYSA-N 50036920 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4a,5,6,7,8,8a-hexahydro-2H-phthalazin-1-one::CHEMBL83625 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036920&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15183280 103944561 CHEMBL83625 ZINC26572457 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057637 O=c1n(CCCCN2CCN(CC2)c2nsc3ccccc23)cnc2ccccc12 InChI=1S/C23H25N5OS/c29-23-18-7-1-3-9-20(18)24-17-28(23)12-6-5-11-26-13-15-27(16-14-26)22-19-8-2-4-10-21(19)30-25-22/h1-4,7-10,17H,5-6,11-16H2 KZJJPWMLHGEQSC-UHFFFAOYSA-N 50036925 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3H-quinazolin-4-one::CHEMBL314370 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036925&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10454774 103944566 CHEMBL314370 ZINC13738139 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057640 O=C1Cc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H26N4O2S/c29-22-17-18-7-1-2-8-19(18)24(30)28(22)12-6-5-11-26-13-15-27(16-14-26)23-20-9-3-4-10-21(20)31-25-23/h1-4,7-10H,5-6,11-17H2 GVEWBUJRQFIULE-UHFFFAOYSA-N 50036926 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4H-isoquinoline-1,3-dione::CHEMBL83454 D(2) dopamine receptor Rattus norvegicus 94 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036926&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10455602 103944567 CHEMBL83454 ZINC13738136 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057642 O=c1n(CCCCN2CCN(CC2)c2nsc3ccccc23)nnc2ccccc12 InChI=1S/C22H24N6OS/c29-22-17-7-1-3-9-19(17)23-25-28(22)12-6-5-11-26-13-15-27(16-14-26)21-18-8-2-4-10-20(18)30-24-21/h1-4,7-10H,5-6,11-16H2 KOZOUZJEVQYQPK-UHFFFAOYSA-N 50036917 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3H-benzo[d][1,2,3]triazin-4-one::CHEMBL314043 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10093607 103944558 CHEMBL314043 ZINC13738135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057645 O=c1n(CCCCN2CCN(CC2)c2nsc3ccccc23)[nH]c2ccccc12 InChI=1S/C22H25N5OS/c28-22-17-7-1-3-9-19(17)23-27(22)12-6-5-11-25-13-15-26(16-14-25)21-18-8-2-4-10-20(18)29-24-21/h1-4,7-10,23H,5-6,11-16H2 HQQJMZBOHALAQF-UHFFFAOYSA-N 50036924 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-1,2-dihydro-indazol-3-one::CHEMBL86401 D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10069979 103944565 CHEMBL86401 ZINC13738133 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057646 O=c1n(CCCCN2CCN(CC2)c2nsc3ccccc23)ncc2ccccc12 InChI=1S/C23H25N5OS/c29-23-19-8-2-1-7-18(19)17-24-28(23)12-6-5-11-26-13-15-27(16-14-26)22-20-9-3-4-10-21(20)30-25-22/h1-4,7-10,17H,5-6,11-16H2 UMDBFJMJDROUKJ-UHFFFAOYSA-N 50036929 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2H-phthalazin-1-one::CHEMBL85647 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036929&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10387365 103944570 CHEMBL85647 ZINC12356376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057648 CCOC(=O)n1n(CCCCN2CCN(CC2)c2nsc3ccccc23)c(=O)c2ccccc12 InChI=1S/C25H29N5O3S/c1-2-33-25(32)30-21-11-5-3-9-19(21)24(31)29(30)14-8-7-13-27-15-17-28(18-16-27)23-20-10-4-6-12-22(20)34-26-23/h3-6,9-12H,2,7-8,13-18H2,1H3 FWRZTTGLYSGBCQ-UHFFFAOYSA-N 50036931 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-oxo-2,3-dihydro-indazole-1-carboxylic acid ethyl ester::CHEMBL83510 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036931&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10096660 103944572 CHEMBL83510 ZINC13738132 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057650 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057656 O=c1n(CCCCN2CCN(CC2)c2nsc3ccccc23)sc2ccccc12 InChI=1S/C22H24N4OS2/c27-22-18-8-2-4-10-20(18)29-26(22)12-6-5-11-24-13-15-25(16-14-24)21-17-7-1-3-9-19(17)28-23-21/h1-4,7-10H,5-6,11-16H2 FRCBWZUARWAHEX-UHFFFAOYSA-N 50036921 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-benzo[d]isothiazol-3-one::CHEMBL314684 D(2) dopamine receptor Rattus norvegicus 600 ChEMBL 10.1021/jm00042a008 10.7270/Q2G15ZWF 7914539 Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Burroughs Wellcome Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10002491 103944562 CHEMBL314684 ZINC13738137 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054395 CCCN(CCC)[C@@H]1CCc2cc(F)c3[nH]ccc3c2C1 InChI=1S/C18H25FN2/c1-3-9-21(10-4-2)14-6-5-13-11-17(19)18-15(7-8-20-18)16(13)12-14/h7-8,11,14,20H,3-6,9-10,12H2,1-2H3/t14-/m1/s1 YCTBHVBIEDZWCH-CQSZACIVSA-N 50035317 ((R)-4-Fluoro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL70710 D(2) dopamine receptor Rattus norvegicus 7.8 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035317&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10062659 103943343 CHEMBL70710 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054396 CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m1/s1 DSEPKSLFXGYPIU-MRXNPFEDSA-N 50035303 (R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL71625 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035303&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10870264 103943329 CHEMBL71625 ZINC03782839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054401 CCCN(CCC)C1CCc2cc(F)c3[nH]cc(C#N)c3c2C1 InChI=1S/C19H24FN3/c1-3-7-23(8-4-2)15-6-5-13-9-17(20)19-18(16(13)10-15)14(11-21)12-22-19/h9,12,15,22H,3-8,10H2,1-2H3 YNVHOSVITIKRBS-UHFFFAOYSA-N 50035313 8-Dipropylamino-4-fluoro-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbonitrile::CHEMBL71474 D(2) dopamine receptor Rattus norvegicus 72 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035313&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10358224 103943339 CHEMBL71474 ZINC13741697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054408 CCCN(CCC)C1CCc2ccc3[nH]cc(C#N)c3c2C1 InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3 ODCNQSRYNGLVNW-UHFFFAOYSA-N 50035326 8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbonitrile::CHEMBL70589 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9994674 103943352 CHEMBL70589 ZINC13738694 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054409 CCCN(CCC)C1CCc2ccc3[nH]cc(SC)c3c2C1 InChI=1S/C19H28N2S/c1-4-10-21(11-5-2)15-8-6-14-7-9-17-19(16(14)12-15)18(22-3)13-20-17/h7,9,13,15,20H,4-6,8,10-12H2,1-3H3 YGRQUNNODUOAHB-UHFFFAOYSA-N 50035334 (1-Methylsulfanyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL306869 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9973090 103943360 CHEMBL306869 ZINC13741725 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054418 CCCN(CCC)C1CCc2ccc3[nH]cc(CC(F)(F)F)c3c2C1 InChI=1S/C20H27F3N2/c1-3-9-25(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-24-18)12-20(21,22)23/h6,8,13,16,24H,3-5,7,9-12H2,1-2H3 LKUMKJQSYINUSG-UHFFFAOYSA-N 50035301 CHEMBL71899::Dipropyl-[1-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035301&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10247448 103943327 CHEMBL71899 ZINC13738699 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054423 CCCN(CCC)C1CCc2ccc3[nH]cc(C(C)=O)c3c2C1 InChI=1S/C20H28N2O/c1-4-10-22(11-5-2)16-8-6-15-7-9-19-20(17(15)12-16)18(13-21-19)14(3)23/h7,9,13,16,21H,4-6,8,10-12H2,1-3H3 VMXHWDJFMZJHSQ-UHFFFAOYSA-N 50035333 1-(8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-ethanone::CHEMBL71395 D(2) dopamine receptor Rattus norvegicus 206 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035333&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9972838 103943359 CHEMBL71395 ZINC13741709 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054428 CCCN(CCC)C1CCc2ccc3NC(=O)Cc3c2C1 InChI=1S/C18H26N2O/c1-3-9-20(10-4-2)14-7-5-13-6-8-17-16(15(13)11-14)12-18(21)19-17/h6,8,14H,3-5,7,9-12H2,1-2H3,(H,19,21) BWVZSNTTXZIRLY-UHFFFAOYSA-N 50035308 8-Dipropylamino-1,3,6,7,8,9-hexahydro-benzo[e]indol-2-one::CHEMBL71091 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035308&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10016864 103943334 CHEMBL71091 ZINC13741717 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054430 CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C(=O)C(N)=O)c3c2C1 InChI=1S/C20H27N3O2/c1-3-9-23(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(12-22-17)19(24)20(21)25/h6,8,12,14,22H,3-5,7,9-11H2,1-2H3,(H2,21,25)/t14-/m1/s1 YHKGAKFTSNNUIP-CQSZACIVSA-N 50035331 2-((R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-2-oxo-acetamide::CHEMBL71247 D(2) dopamine receptor Rattus norvegicus 472.0 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035331&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9997422 103943357 CHEMBL71247 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054440 CCCN(CCC)[C@H]1CCc2cc(F)c3[nH]ccc3c2C1 InChI=1S/C18H25FN2/c1-3-9-21(10-4-2)14-6-5-13-11-17(19)18-15(7-8-20-18)16(13)12-14/h7-8,11,14,20H,3-6,9-10,12H2,1-2H3/t14-/m0/s1 YCTBHVBIEDZWCH-AWEZNQCLSA-N 50035299 ((S)-4-Fluoro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL304573 D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10401862 103943325 CHEMBL304573 ZINC13741693 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054452 CCCN(CCC)C1CCc2cc(F)c3[nH]cc(C=O)c3c2C1 InChI=1S/C19H25FN2O/c1-3-7-22(8-4-2)15-6-5-13-9-17(20)19-18(16(13)10-15)14(12-23)11-21-19/h9,11-12,15,21H,3-8,10H2,1-2H3 ICOOOYKBBQSJND-UHFFFAOYSA-N 50035319 8-Dipropylamino-4-fluoro-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL441256 D(2) dopamine receptor Rattus norvegicus 65 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11723305 103943345 CHEMBL441256 ZINC13741694 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054453 CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1 InChI=1S/C18H25ClN2/c1-3-9-21(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(19)12-20-17/h6,8,12,14,20H,3-5,7,9-11H2,1-2H3 AXWVKOPRBOVXMC-UHFFFAOYSA-N 50035306 (1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL303021 D(2) dopamine receptor Rattus norvegicus 9.8 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035306&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11779840 103943332 CHEMBL303021 ZINC13738697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054458 CCCN(CCC)C1CCc2cc(F)c3[nH]cc(CCC)c3c2C1 InChI=1S/C21H31FN2/c1-4-7-16-14-23-21-19(22)12-15-8-9-17(13-18(15)20(16)21)24(10-5-2)11-6-3/h12,14,17,23H,4-11,13H2,1-3H3 HCDLXJXEGJTMHB-UHFFFAOYSA-N 50035325 (4-Fluoro-1-propyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL71663 D(2) dopamine receptor Rattus norvegicus 5.9 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10088038 103943351 CHEMBL71663 ZINC13741701 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056585 Fc1ccc(cc1)C(=O)CCCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 InChI=1S/C24H24F2N2O/c25-16-6-4-15(5-7-16)23(29)3-1-2-12-28-18-9-11-22(28)24-19-13-17(26)8-10-20(19)27-21(24)14-18/h4-8,10,13,18,22,27H,1-3,9,11-12,14H2 VFPYMAAKRGRXBH-UHFFFAOYSA-N 50036650 (7R,10S)-5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::(7S,10R)-5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::CHEMBL291254 D(2) dopamine receptor Rattus norvegicus 755 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036650&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646166 103944291 CHEMBL291254 ZINC13827343 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056587 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056588 Fc1ccc2c(CCCN3C4CCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 InChI=1S/C23H21F2N3O/c24-13-4-7-18-17(10-13)23-20(26-18)12-15-5-8-21(23)28(15)9-1-2-19-16-6-3-14(25)11-22(16)29-27-19/h3-4,6-7,10-11,15,21,26H,1-2,5,8-9,12H2 FUWBTIWZNWXCRS-UHFFFAOYSA-N 50036651 (7R,10S)-1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::(7S,10R)-1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::CHEMBL284172 D(2) dopamine receptor Rattus norvegicus 233 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646187 103944292 CHEMBL284172 ZINC13827352 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056591 Fc1ccc(cc1)C(=O)CCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 InChI=1S/C23H22F2N2O/c24-15-5-3-14(4-6-15)22(28)2-1-11-27-17-8-10-21(27)23-18-12-16(25)7-9-19(18)26-20(23)13-17/h3-7,9,12,17,21,26H,1-2,8,10-11,13H2 SWEUQJQJCWSLBM-UHFFFAOYSA-N 50036648 (7R,10S)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::(7S,10R)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::CHEMBL38151 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646133 103944289 CHEMBL38151 ZINC13827314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056596 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.470000 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056597 Fc1ccc2c(CCCCN3C4CCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 InChI=1S/C24H23F2N3O/c25-14-5-8-19-18(11-14)24-21(27-19)13-16-6-9-22(24)29(16)10-2-1-3-20-17-7-4-15(26)12-23(17)30-28-20/h4-5,7-8,11-12,16,22,27H,1-3,6,9-10,13H2 RKKLLFDATFBVDR-UHFFFAOYSA-N 50036649 (7R,10S)-1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::(7S,10R)-1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::CHEMBL284163 D(2) dopamine receptor Rattus norvegicus 0.710 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646191 103944290 CHEMBL284163 ZINC13827354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056605 Fc1ccc(cc1)C(=O)CCCCN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C24H25FN2O/c25-17-10-8-16(9-11-17)23(28)7-3-4-14-27-18-12-13-22(27)24-19-5-1-2-6-20(19)26-21(24)15-18/h1-2,5-6,8-11,18,22,26H,3-4,7,12-15H2 AFVUFWHJUYVTQW-UHFFFAOYSA-N 50036647 (7R,10S)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::(7S,10R)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::CHEMBL285712 D(2) dopamine receptor Rattus norvegicus 1.70 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9842628 103944288 CHEMBL285712 ZINC03801105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056613 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 168 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054463 CCCN(CCC)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3 DSEPKSLFXGYPIU-UHFFFAOYSA-N 50035320 (+/-)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL304426 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 178081 103943346 CHEMBL304426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054467 CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C#N)c3c2C1 InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3/t16-/m0/s1 ODCNQSRYNGLVNW-INIZCTEOSA-N 50035324 (S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbonitrile::CHEMBL71804 D(2) dopamine receptor Rattus norvegicus 419.0 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10379784 103943350 CHEMBL71804 ZINC13738695 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054477 CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1 GKDJCOLVXBCNNK-HNNXBMFYSA-N 50035307 CHEMBL302171::Dipropyl-(S)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::S-(-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035307&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10468376 103943333 CHEMBL302171 ZINC13738689 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054479 CCCN(CCC)C1CCc2cc(F)c3n(C)cc(C=O)c3c2C1 InChI=1S/C20H27FN2O/c1-4-8-23(9-5-2)16-7-6-14-10-18(21)20-19(17(14)11-16)15(13-24)12-22(20)3/h10,12-13,16H,4-9,11H2,1-3H3 JYSLVWOAWZHHQD-UHFFFAOYSA-N 50035314 8-Dipropylamino-4-fluoro-3-methyl-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL71319 D(2) dopamine receptor Rattus norvegicus 1034 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10065239 103943340 CHEMBL71319 ZINC13741705 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054482 CCCNC1CCc2cc(F)ccc2C1 InChI=1S/C13H18FN/c1-2-7-15-13-6-4-10-8-12(14)5-3-11(10)9-13/h3,5,8,13,15H,2,4,6-7,9H2,1H3 FPJDYLPAAFVKBL-UHFFFAOYSA-N 50035312 (6-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::CHEMBL302373 D(2) dopamine receptor Rattus norvegicus 162 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035312&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10398118 103943338 CHEMBL302373 ZINC13741689 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054486 CCCN(CCC)C1CCc2cc(F)c3n(C)ccc3c2C1 InChI=1S/C19H27FN2/c1-4-9-22(10-5-2)15-7-6-14-12-18(20)19-16(17(14)13-15)8-11-21(19)3/h8,11-12,15H,4-7,9-10,13H2,1-3H3 VAATVGITWGBTOR-UHFFFAOYSA-N 50035318 (4-Fluoro-3-methyl-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL70882 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035318&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425027 103943344 CHEMBL70882 ZINC13741703 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054487 CCCN(CCC)[C@@H]1CCc2cc(F)c3[nH]cc(C=O)c3c2C1 InChI=1S/C19H25FN2O/c1-3-7-22(8-4-2)15-6-5-13-9-17(20)19-18(16(13)10-15)14(12-23)11-21-19/h9,11-12,15,21H,3-8,10H2,1-2H3/t15-/m1/s1 ICOOOYKBBQSJND-OAHLLOKOSA-N 50035335 (R)-8-Dipropylamino-4-fluoro-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL71176 D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1021/jm00012a021 10.7270/Q24T6HD0 7783152 Stjernlof, P; Ennis, MD; Hansson, LO; Hoffman, RL; Ghazal, NB; Sundell, S; Smith, MW; Svensson, K; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035335&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10448470 103943361 CHEMBL71176 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056848 Clc1ccc(OCCN2CCc3ccccc3CC2)c2CC(=O)Nc12 InChI=1S/C20H21ClN2O2/c21-17-5-6-18(16-13-19(24)22-20(16)17)25-12-11-23-9-7-14-3-1-2-4-15(14)8-10-23/h1-6H,7-13H2,(H,22,24) DZAIXMOGMCWKEV-UHFFFAOYSA-N 50077574 7-Chloro-4-[2-(1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL292253 D(2) dopamine receptor Rattus norvegicus 0.550000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44303541 103970343 CHEMBL292253 ZINC26168677 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056849 FC(F)(F)C(=O)c1c[nH]c2cccc(OCCNCc3ccccc3)c12 InChI=1S/C19H17F3N2O2/c20-19(21,22)18(25)14-12-24-15-7-4-8-16(17(14)15)26-10-9-23-11-13-5-2-1-3-6-13/h1-8,12,23-24H,9-11H2 NQQDGDDHTBBKPN-UHFFFAOYSA-N 50077589 1-[4-(2-Benzylamino-ethoxy)-1H-indol-3-yl]-2,2,2-trifluoro-ethanone::CHEMBL60783 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077589&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9928915 103970358 CHEMBL60783 ZINC01903125 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056850 O=C1Cc2c(N1)ccc1CC[C@H](CNCc3ccccc3)Oc21 InChI=1S/C19H20N2O2/c22-18-10-16-17(21-18)9-7-14-6-8-15(23-19(14)16)12-20-11-13-4-2-1-3-5-13/h1-5,7,9,15,20H,6,8,10-12H2,(H,21,22)/t15-/m1/s1 NPATVCXCHCPFCB-OAHLLOKOSA-N 50077581 (R)-2-(Benzylamino-methyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indol-8-one::CHEMBL303556 D(2) dopamine receptor Rattus norvegicus 5.9 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10063875 103970350 CHEMBL303556 ZINC13586902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056851 Oc1ccc2CC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m1/s1 DWUAAOIZQFTYQP-MRXNPFEDSA-N 50061669 (R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL134807::CHEMBL64553 D(2) dopamine receptor Rattus norvegicus 0.200000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378389 103957219 CHEMBL134807CHEMBL64553 ZINC13527706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056852 Fc1ccc(OCCNc2ccc3ccccc3c2)c2CC(=O)Nc12 InChI=1S/C20H17FN2O2/c21-17-7-8-18(16-12-19(24)23-20(16)17)25-10-9-22-15-6-5-13-3-1-2-4-14(13)11-15/h1-8,11,22H,9-10,12H2,(H,23,24) SHSCMNFGMPWQKM-UHFFFAOYSA-N 50077601 7-Fluoro-4-[2-(naphthalen-2-ylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL62290 D(2) dopamine receptor Rattus norvegicus 0.630000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640595 103970370 CHEMBL62290 ZINC26168709 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056853 Oc1ccc2NC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C16H18N2O2/c19-13-6-7-15-16(8-13)20-14(11-18-15)10-17-9-12-4-2-1-3-5-12/h1-8,14,17-19H,9-11H2/t14-/m0/s1 OFRVVOZORYSDMF-AWEZNQCLSA-N 50077584 (S)-2-(Benzylamino-methyl)-3,4-dihydro-2H-benzo[1,4]oxazin-7-ol::CHEMBL59992 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077584&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44303196 103970353 CHEMBL59992 ZINC13798062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056856 Clc1ccc(OCCNc2ccc3ccccc3c2)c2CC(=O)Nc12 InChI=1S/C20H17ClN2O2/c21-17-7-8-18(16-12-19(24)23-20(16)17)25-10-9-22-15-6-5-13-3-1-2-4-14(13)11-15/h1-8,11,22H,9-10,12H2,(H,23,24) FDCFNYCBHMWNKL-UHFFFAOYSA-N 50077566 7-Chloro-4-[2-(naphthalen-2-ylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL294538 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10831870 103970335 CHEMBL294538 ZINC26168210 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056857 O=C1Cc2c(N1)cccc2OCCNCc1ccccc1 InChI=1S/C17H18N2O2/c20-17-11-14-15(19-17)7-4-8-16(14)21-10-9-18-12-13-5-2-1-3-6-13/h1-8,18H,9-12H2,(H,19,20) CVWQKEFTSSJDLS-UHFFFAOYSA-N 50077578 4-(2-Benzylamino-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL59752 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903877 103970347 CHEMBL59752 ZINC01903144 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056858 Fc1ccc(OCCNCc2ccc(cc2)-c2ccccc2)c2CC(=O)Nc12 InChI=1S/C23H21FN2O2/c24-20-10-11-21(19-14-22(27)26-23(19)20)28-13-12-25-15-16-6-8-18(9-7-16)17-4-2-1-3-5-17/h1-11,25H,12-15H2,(H,26,27) PLXCESBDIJXCGL-UHFFFAOYSA-N 50077590 4-{2-[(Biphenyl-4-ylmethyl)-amino]-ethoxy}-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL64798 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077590&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10547536 103970359 CHEMBL64798 ZINC26165572 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056859 Fc1ccc(OCCNCc2ccccc2)c2CC(=O)Nc12 InChI=1S/C17H17FN2O2/c18-14-6-7-15(13-10-16(21)20-17(13)14)22-9-8-19-11-12-4-2-1-3-5-12/h1-7,19H,8-11H2,(H,20,21) OSMFCZGZJMRMAV-UHFFFAOYSA-N 50077597 4-(2-Benzylamino-ethoxy)-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL63491 D(2) dopamine receptor Rattus norvegicus 5.3 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077597&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10732973 103970366 CHEMBL63491 ZINC26165582 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056860 FC(F)(F)C(=O)c1c[nH]c2c(Cl)ccc(OCCNCc3ccccc3)c12 InChI=1S/C19H16ClF3N2O2/c20-14-6-7-15(27-9-8-24-10-12-4-2-1-3-5-12)16-13(11-25-17(14)16)18(26)19(21,22)23/h1-7,11,24-25H,8-10H2 QBNVFACVZPZVHG-UHFFFAOYSA-N 50077594 1-[4-(2-Benzylamino-ethoxy)-7-chloro-1H-indol-3-yl]-2,2,2-trifluoro-ethanone::CHEMBL60840 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9908760 103970363 CHEMBL60840 ZINC01903140 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056861 C(NCc1ccccc1)[C@H]1CCc2ccc3[nH]ccc3c2O1 InChI=1S/C19H20N2O/c1-2-4-14(5-3-1)12-20-13-16-8-6-15-7-9-18-17(10-11-21-18)19(15)22-16/h1-5,7,9-11,16,20-21H,6,8,12-13H2/t16-/m1/s1 AERWLNZHDGJKMO-MRXNPFEDSA-N 50077569 Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]indol-2-yl)methyl]-amine::CHEMBL60185 D(2) dopamine receptor Rattus norvegicus 1.9 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10613605 103970338 CHEMBL60185 ZINC12356074 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056862 CCCCNCCOc1ccc(Cl)c2NC(=O)Cc12 InChI=1S/C14H19ClN2O2/c1-2-3-6-16-7-8-19-12-5-4-11(15)14-10(12)9-13(18)17-14/h4-5,16H,2-3,6-9H2,1H3,(H,17,18) UGVNNOUXZAJBHJ-UHFFFAOYSA-N 50077583 4-(2-Butylamino-ethoxy)-7-chloro-1,3-dihydro-indol-2-one::CHEMBL304894 D(2) dopamine receptor Rattus norvegicus 0.840000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077583&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10802894 103970352 CHEMBL304894 ZINC26162397 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056864 Clc1c[nH]c2c(Cl)ccc(OCCNCc3ccc(Cl)cc3)c12 InChI=1S/C17H15Cl3N2O/c18-12-3-1-11(2-4-12)9-21-7-8-23-15-6-5-13(19)17-16(15)14(20)10-22-17/h1-6,10,21-22H,7-9H2 ZCVWXRHTDZMYSR-UHFFFAOYSA-N 50077595 (4-Chloro-benzyl)-[2-(3,7-dichloro-1H-indol-4-yloxy)-ethyl]-amine::CHEMBL60361 D(2) dopamine receptor Rattus norvegicus 77 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9799480 103970364 CHEMBL60361 ZINC01903134 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056866 Clc1c[nH]c2cccc(OCCNCCCCc3ccccc3)c12 InChI=1S/C20H23ClN2O/c21-17-15-23-18-10-6-11-19(20(17)18)24-14-13-22-12-5-4-9-16-7-2-1-3-8-16/h1-3,6-8,10-11,15,22-23H,4-5,9,12-14H2 MYZONUPBZFDODL-UHFFFAOYSA-N 50077563 CHEMBL64420::[2-(3-Chloro-1H-indol-4-yloxy)-ethyl]-(4-phenyl-butyl)-amine D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9884480 103970332 CHEMBL64420 ZINC01903137 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056867 Clc1ccc(OCCNCc2ccsc2)c2CC(=O)Nc12 InChI=1S/C15H15ClN2O2S/c16-12-1-2-13(11-7-14(19)18-15(11)12)20-5-4-17-8-10-3-6-21-9-10/h1-3,6,9,17H,4-5,7-8H2,(H,18,19) YJANKLWIHLPIFX-UHFFFAOYSA-N 50077580 7-Chloro-4-{2-[(thiophen-3-ylmethyl)-amino]-ethoxy}-1,3-dihydro-indol-2-one::CHEMBL64466 D(2) dopamine receptor Rattus norvegicus 0.240000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077580&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840168 103970349 CHEMBL64466 ZINC26165738 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056868 Clc1ccc(OCCNCc2ccccc2)c2cc[nH]c12 InChI=1S/C17H17ClN2O/c18-15-6-7-16(14-8-9-20-17(14)15)21-11-10-19-12-13-4-2-1-3-5-13/h1-9,19-20H,10-12H2 VWVPMNHCCNZAGX-UHFFFAOYSA-N 50077596 Benzyl-[2-(7-chloro-1H-indol-4-yloxy)-ethyl]-amine::CHEMBL64134 D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077596&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9839319 103970365 CHEMBL64134 ZINC01903129 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056869 C(COc1cccc2[nH]ccc12)NCc1ccccc1 InChI=1S/C17H18N2O/c1-2-5-14(6-3-1)13-18-11-12-20-17-8-4-7-16-15(17)9-10-19-16/h1-10,18-19H,11-13H2 ZEHDEZWEFBOGNZ-UHFFFAOYSA-N 50077576 Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine::CHEMBL64283 D(2) dopamine receptor Rattus norvegicus 9.7 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9838216 103970345 CHEMBL64283 ZINC01903142 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056870 Fc1ccc(OCCN2Cc3ccccc3C2)c2CC(=O)Nc12 InChI=1S/C18H17FN2O2/c19-15-5-6-16(14-9-17(22)20-18(14)15)23-8-7-21-10-12-3-1-2-4-13(12)11-21/h1-6H,7-11H2,(H,20,22) AAMLBIYNFUAPCS-UHFFFAOYSA-N 50077573 4-[2-(1,3-Dihydro-isoindol-2-yl)-ethoxy]-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL300316 D(2) dopamine receptor Rattus norvegicus 2.1 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10638841 103970342 CHEMBL300316 ZINC26154059 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056871 Fc1ccc(OCCNCc2cccc(c2)-c2ccccc2)c2CC(=O)Nc12 InChI=1S/C23H21FN2O2/c24-20-9-10-21(19-14-22(27)26-23(19)20)28-12-11-25-15-16-5-4-8-18(13-16)17-6-2-1-3-7-17/h1-10,13,25H,11-12,14-15H2,(H,26,27) SUNPULXJCJNRPQ-UHFFFAOYSA-N 50077603 4-{2-[(Biphenyl-3-ylmethyl)-amino]-ethoxy}-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL418681 D(2) dopamine receptor Rattus norvegicus 3.9 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077603&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10643240 103970372 CHEMBL418681 ZINC26163524 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056872 NCCOc1ccc(F)c2NC(=O)Cc12 InChI=1S/C10H11FN2O2/c11-7-1-2-8(15-4-3-12)6-5-9(14)13-10(6)7/h1-2H,3-5,12H2,(H,13,14) SGAXOBUAZNCOOR-UHFFFAOYSA-N 50077571 4-(2-Amino-ethoxy)-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL302436 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10703634 103970340 CHEMBL302436 ZINC26162196 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056873 Fc1ccc(OCCNCc2cccs2)c2CC(=O)Nc12 InChI=1S/C15H15FN2O2S/c16-12-3-4-13(11-8-14(19)18-15(11)12)20-6-5-17-9-10-2-1-7-21-10/h1-4,7,17H,5-6,8-9H2,(H,18,19) JRUPYTLRKHUREA-UHFFFAOYSA-N 50077582 7-Fluoro-4-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-1,3-dihydro-indol-2-one::CHEMBL64574 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077582&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10638352 103970351 CHEMBL64574 ZINC26163010 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056874 Fc1ccc(OCCNCCCc2c[nH]c3ccccc23)c2CC(=O)Nc12 InChI=1S/C21H22FN3O2/c22-17-7-8-19(16-12-20(26)25-21(16)17)27-11-10-23-9-3-4-14-13-24-18-6-2-1-5-15(14)18/h1-2,5-8,13,23-24H,3-4,9-12H2,(H,25,26) RTTDUHNRPAYWKJ-UHFFFAOYSA-N 50077577 7-Fluoro-4-{2-[3-(1H-indol-3-yl)-propylamino]-ethoxy}-1,3-dihydro-indol-2-one::CHEMBL60265 D(2) dopamine receptor Rattus norvegicus 0.150000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077577&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618968 103970346 CHEMBL60265 ZINC26154052 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056875 NCCOc1cccc2NC(=O)Cc12 InChI=1S/C10H12N2O2/c11-4-5-14-9-3-1-2-8-7(9)6-10(13)12-8/h1-3H,4-6,11H2,(H,12,13) JZOOPCSBOXTVMN-UHFFFAOYSA-N 50077585 4-(2-Amino-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL416856 D(2) dopamine receptor Rattus norvegicus 268 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077585&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10583903 103970354 CHEMBL416856 ZINC01903147 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056876 Clc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1 InChI=1S/C17H16Cl2N2O2/c18-12-3-1-11(2-4-12)10-20-7-8-23-15-6-5-14(19)17-13(15)9-16(22)21-17/h1-6,20H,7-10H2,(H,21,22) JPSMZWRPAFVXDX-UHFFFAOYSA-N 50077604 7-Chloro-4-[2-(4-chloro-benzylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL302000 D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077604&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10498102 103970373 CHEMBL302000 ZINC26163145 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056877 Fc1ccc(OCCNCc2ccsc2)c2CC(=O)Nc12 InChI=1S/C15H15FN2O2S/c16-12-1-2-13(11-7-14(19)18-15(11)12)20-5-4-17-8-10-3-6-21-9-10/h1-3,6,9,17H,4-5,7-8H2,(H,18,19) YPZRCWNVQVKPJX-UHFFFAOYSA-N 50077600 7-Fluoro-4-{2-[(thiophen-3-ylmethyl)-amino]-ethoxy}-1,3-dihydro-indol-2-one::CHEMBL418510 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077600&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10662428 103970369 CHEMBL418510 ZINC29570361 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056878 Clc1ccc(OCCN2Cc3ccccc3C2)c2CC(=O)Nc12 InChI=1S/C18H17ClN2O2/c19-15-5-6-16(14-9-17(22)20-18(14)15)23-8-7-21-10-12-3-1-2-4-13(12)11-21/h1-6H,7-11H2,(H,20,22) NTOGEDXEDRMFKP-UHFFFAOYSA-N 50077592 7-Chloro-4-[2-(1,3-dihydro-isoindol-2-yl)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL64524 D(2) dopamine receptor Rattus norvegicus 2.9 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077592&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10853769 103970361 CHEMBL64524 ZINC26163138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056879 C(CCc1ccccc1)CNCCOc1cccc2[nH]ccc12 InChI=1S/C20H24N2O/c1-2-7-17(8-3-1)9-4-5-13-21-15-16-23-20-11-6-10-19-18(20)12-14-22-19/h1-3,6-8,10-12,14,21-22H,4-5,9,13,15-16H2 XLIMGWVIUMZMMX-UHFFFAOYSA-N 50077588 CHEMBL59737::[2-(1H-Indol-4-yloxy)-ethyl]-(4-phenyl-butyl)-amine D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077588&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9861435 103970357 CHEMBL59737 ZINC01903127 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056880 Clc1c[nH]c2c(Cl)ccc(OCCNCc3ccccc3)c12 InChI=1S/C17H16Cl2N2O/c18-13-6-7-15(16-14(19)11-21-17(13)16)22-9-8-20-10-12-4-2-1-3-5-12/h1-7,11,20-21H,8-10H2 MOXUIBWAFLAGIL-UHFFFAOYSA-N 50077575 Benzyl-[2-(3,7-dichloro-1H-indol-4-yloxy)-ethyl]-amine::CHEMBL294204 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9862532 103970344 CHEMBL294204 ZINC01903130 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056881 Cc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1 InChI=1S/C18H19ClN2O2/c1-12-2-4-13(5-3-12)11-20-8-9-23-16-7-6-15(19)18-14(16)10-17(22)21-18/h2-7,20H,8-11H2,1H3,(H,21,22) GZDWJPMFRZBGFX-UHFFFAOYSA-N 50077591 7-Chloro-4-[2-(4-methyl-benzylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL305585 D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10711537 103970360 CHEMBL305585 ZINC26149429 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056882 Clc1ccc(OCCNCc2cccs2)c2CC(=O)Nc12 InChI=1S/C15H15ClN2O2S/c16-12-3-4-13(11-8-14(19)18-15(11)12)20-6-5-17-9-10-2-1-7-21-10/h1-4,7,17H,5-6,8-9H2,(H,18,19) MXDAPRHGJIKJMQ-UHFFFAOYSA-N 50077565 7-Chloro-4-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-1,3-dihydro-indol-2-one::CHEMBL60548 D(2) dopamine receptor Rattus norvegicus 0.600000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10663658 103970334 CHEMBL60548 ZINC26161855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056883 O=C1Cc2c(N1)cccc2OCCNCCCCc1ccccc1 InChI=1S/C20H24N2O2/c23-20-15-17-18(22-20)10-6-11-19(17)24-14-13-21-12-5-4-9-16-7-2-1-3-8-16/h1-3,6-8,10-11,21H,4-5,9,12-15H2,(H,22,23) PTTJRNUQRLBAEV-UHFFFAOYSA-N 50077602 4-[2-(4-Phenyl-butylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL61671 D(2) dopamine receptor Rattus norvegicus 0.230000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10520031 103970371 CHEMBL61671 ZINC26150427 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056884 CN(CCOc1cccc2NC(=O)Cc12)Cc1ccccc1 InChI=1S/C18H20N2O2/c1-20(13-14-6-3-2-4-7-14)10-11-22-17-9-5-8-16-15(17)12-18(21)19-16/h2-9H,10-13H2,1H3,(H,19,21) ZCTQZPVZSXAFAK-UHFFFAOYSA-N 50077568 4-[2-(Benzyl-methyl-amino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL434407 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10661630 103970337 CHEMBL434407 ZINC00023355 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056885 Clc1ccc(OCCNCc2ccc(cc2)-c2ccccc2)c2CC(=O)Nc12 InChI=1S/C23H21ClN2O2/c24-20-10-11-21(19-14-22(27)26-23(19)20)28-13-12-25-15-16-6-8-18(9-7-16)17-4-2-1-3-5-17/h1-11,25H,12-15H2,(H,26,27) XJSQDZJJAFIJPV-UHFFFAOYSA-N 50077598 4-{2-[(Biphenyl-4-ylmethyl)-amino]-ethoxy}-7-chloro-1,3-dihydro-indol-2-one::CHEMBL61665 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077598&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10739299 103970367 CHEMBL61665 ZINC29571663 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056886 Oc1ccc2OC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C16H17NO3/c18-13-6-7-15-16(8-13)20-14(11-19-15)10-17-9-12-4-2-1-3-5-12/h1-8,14,17-18H,9-11H2/t14-/m0/s1 DYWYWIOQKKRAST-AWEZNQCLSA-N 50061642 (S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]dioxin-6-ol; oxalic acid::CHEMBL300571::CHEMBL423890 D(2) dopamine receptor Rattus norvegicus 5.7 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10612157 103957192 CHEMBL300571CHEMBL423890 ZINC13775979 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056887 Clc1ccc(OCCNCc2ccccc2)c2CC(=O)Nc12 InChI=1S/C17H17ClN2O2/c18-14-6-7-15(13-10-16(21)20-17(13)14)22-9-8-19-11-12-4-2-1-3-5-12/h1-7,19H,8-11H2,(H,20,21) MBLREOGMGHDMJH-UHFFFAOYSA-N 50077572 4-(2-Benzylamino-ethoxy)-7-chloro-1,3-dihydro-indol-2-one::CHEMBL435182 D(2) dopamine receptor Rattus norvegicus 2.8 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10313715 103970341 CHEMBL435182 ZINC26150459 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056888 CNCCOc1cccc2NC(=O)Cc12 InChI=1S/C11H14N2O2/c1-12-5-6-15-10-4-2-3-9-8(10)7-11(14)13-9/h2-4,12H,5-7H2,1H3,(H,13,14) STMJSLDMROVPBX-UHFFFAOYSA-N 50077567 4-(2-Methylamino-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL64238 D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10822156 103970336 CHEMBL64238 ZINC01903146 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056889 Fc1ccc(CNCCOc2ccc(Cl)c3[nH]cc(Cl)c23)cc1 InChI=1S/C17H15Cl2FN2O/c18-13-5-6-15(16-14(19)10-22-17(13)16)23-8-7-21-9-11-1-3-12(20)4-2-11/h1-6,10,21-22H,7-9H2 GEHFGDHALWGGMK-UHFFFAOYSA-N 50077564 CHEMBL64345::[2-(3,7-Dichloro-1H-indol-4-yloxy)-ethyl]-(4-fluoro-benzyl)-amine D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9884884 103970333 CHEMBL64345 ZINC01903132 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056890 CN(CCCC(=O)c1ccc(F)cc1)CCOc1cccc2NC(=O)Cc12 InChI=1S/C21H23FN2O3/c1-24(11-3-5-19(25)15-7-9-16(22)10-8-15)12-13-27-20-6-2-4-18-17(20)14-21(26)23-18/h2,4,6-10H,3,5,11-14H2,1H3,(H,23,26) IOVXZPKVVVPHDX-UHFFFAOYSA-N 50077586 4-(2-{[4-(4-Fluoro-phenyl)-4-oxo-butyl]-methyl-amino}-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL60900 D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10714219 103970355 CHEMBL60900 ZINC26158976 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056891 Clc1c[nH]c2c(Cl)ccc(OCCNCc3cccs3)c12 InChI=1S/C15H14Cl2N2OS/c16-11-3-4-13(14-12(17)9-19-15(11)14)20-6-5-18-8-10-2-1-7-21-10/h1-4,7,9,18-19H,5-6,8H2 KAHGPKAAVFDLKE-UHFFFAOYSA-N 50077579 CHEMBL64509::[2-(3,7-Dichloro-1H-indol-4-yloxy)-ethyl]-thiophen-2-ylmethyl-amine D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077579&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10783399 103970348 CHEMBL64509 ZINC01903135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056892 Oc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2 VBTFJGYCISLKEQ-UHFFFAOYSA-N 50069914 3-(2-Benzylamino-ethoxy)-phenol::CHEMBL64508 D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069914&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11776546 103963876 CHEMBL64508 ZINC12355952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056893 Fc1ccc(OCCNCC2CCCCC2)c2CC(=O)Nc12 InChI=1S/C17H23FN2O2/c18-14-6-7-15(13-10-16(21)20-17(13)14)22-9-8-19-11-12-4-2-1-3-5-12/h6-7,12,19H,1-5,8-11H2,(H,20,21) IWPODTZOHNIYFY-UHFFFAOYSA-N 50077587 4-[2-(Cyclohexylmethyl-amino)-ethoxy]-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL59750 D(2) dopamine receptor Rattus norvegicus 5.6 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10757042 103970356 CHEMBL59750 ZINC26162345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056894 CN(CCOc1ccc(Cl)c2NC(=O)Cc12)Cc1ccccc1 InChI=1S/C18H19ClN2O2/c1-21(12-13-5-3-2-4-6-13)9-10-23-16-8-7-15(19)18-14(16)11-17(22)20-18/h2-8H,9-12H2,1H3,(H,20,22) KNYXWJRBLXUOLM-UHFFFAOYSA-N 50077593 4-[2-(Benzyl-methyl-amino)-ethoxy]-7-chloro-1,3-dihydro-indol-2-one::CHEMBL59501 D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077593&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10544453 103970362 CHEMBL59501 ZINC29570549 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056947 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 820 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057027 CC(C)Oc1ccccc1N1CCN(Cc2ccccc2CN2CCCCC2=O)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-12-6-5-11-24(25)28-17-15-27(16-18-28)19-22-9-3-4-10-23(22)20-29-14-8-7-13-26(29)30/h3-6,9-12,21H,7-8,13-20H2,1-2H3 BKOZXYDJNCUNBD-UHFFFAOYSA-N 50029319 1-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-piperidin-2-one::CHEMBL10105 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00034a003 10.7270/Q23R0RXB 7909336 Reitz, AB; Bennett, DJ; Blum, PS; Codd, EE; Maryanoff, CA; Ortegon, ME; Renzi, MJ; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10387475 103938390 CHEMBL10105 ZINC52956220 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057030 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.37 ChEMBL 10.1021/jm00034a003 10.7270/Q23R0RXB 7909336 Reitz, AB; Bennett, DJ; Blum, PS; Codd, EE; Maryanoff, CA; Ortegon, ME; Renzi, MJ; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057033 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3CCCCC3=O)c2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-11-4-3-10-24(25)28-16-14-27(15-17-28)19-22-8-7-9-23(18-22)20-29-13-6-5-12-26(29)30/h3-4,7-11,18,21H,5-6,12-17,19-20H2,1-2H3 RTJRXNDVJCWGSK-UHFFFAOYSA-N 50029300 1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-piperidin-2-one::CHEMBL416703 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00034a003 10.7270/Q23R0RXB 7909336 Reitz, AB; Bennett, DJ; Blum, PS; Codd, EE; Maryanoff, CA; Ortegon, ME; Renzi, MJ; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029300&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9802305 103938371 CHEMBL416703 ZINC00598896 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057036 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-12-5-4-11-24(25)28-17-15-27(16-18-28)20-22-9-8-10-23(19-22)26(30)29-13-6-3-7-14-29/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3 ZKZFPRUSWCYSGT-UHFFFAOYSA-N 50029257 (3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)phenyl)(piperidin-1-yl)methanone::CHEMBL10085::RWJ-377796::mazapertine::{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm00034a003 10.7270/Q23R0RXB 7909336 Reitz, AB; Bennett, DJ; Blum, PS; Codd, EE; Maryanoff, CA; Ortegon, ME; Renzi, MJ; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60820 103938328 CHEMBL10085 ZINC52956332 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057044 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)cc2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-8-4-3-7-24(25)28-17-15-27(16-18-28)19-22-10-12-23(13-11-22)20-29-14-6-5-9-26(29)30/h3-4,7-8,10-13,21H,5-6,9,14-20H2,1-2H3 AQMSXOSMVXZSPU-UHFFFAOYSA-N 50029306 1-{4-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-piperidin-2-one::CHEMBL275045 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00034a003 10.7270/Q23R0RXB 7909336 Reitz, AB; Bennett, DJ; Blum, PS; Codd, EE; Maryanoff, CA; Ortegon, ME; Renzi, MJ; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029306&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742940 103938377 CHEMBL275045 ZINC00835560 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057047 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1021/jm00034a003 10.7270/Q23R0RXB 7909336 Reitz, AB; Bennett, DJ; Blum, PS; Codd, EE; Maryanoff, CA; Ortegon, ME; Renzi, MJ; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057051 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C25H36N4O2/c1-20(2)31-24-9-5-4-8-23(24)28-16-14-27(15-17-28)18-21-11-12-22(26(21)3)19-29-13-7-6-10-25(29)30/h4-5,8-9,11-12,20H,6-7,10,13-19H2,1-3H3 BLFPEKXTSDYQOQ-UHFFFAOYSA-N 50001869 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL428175::RWJ-25730 D(2) dopamine receptor Rattus norvegicus 0.8 ChEMBL 10.1021/jm00034a003 10.7270/Q23R0RXB 7909336 Reitz, AB; Bennett, DJ; Blum, PS; Codd, EE; Maryanoff, CA; Ortegon, ME; Renzi, MJ; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9910257 103916236 CHEMBL428175 ZINC53255684 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057054 CC(C)Oc1ccccc1N1CCN(Cc2ccccc2C(=O)N2CCCCC2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-13-7-6-12-24(25)28-18-16-27(17-19-28)20-22-10-4-5-11-23(22)26(30)29-14-8-3-9-15-29/h4-7,10-13,21H,3,8-9,14-20H2,1-2H3 XOSWFKITGQDVJE-UHFFFAOYSA-N 50036812 CHEMBL10327::{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 37 ChEMBL 10.1021/jm00034a003 10.7270/Q23R0RXB 7909336 Reitz, AB; Bennett, DJ; Blum, PS; Codd, EE; Maryanoff, CA; Ortegon, ME; Renzi, MJ; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036812&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10364898 103944453 CHEMBL10327 ZINC13600956 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057058 CC(C)Oc1ccccc1N1CCN(Cc2ccc(cc2)C(=O)N2CCCCC2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-9-5-4-8-24(25)28-18-16-27(17-19-28)20-22-10-12-23(13-11-22)26(30)29-14-6-3-7-15-29/h4-5,8-13,21H,3,6-7,14-20H2,1-2H3 SYNTUEMBUHFZEZ-UHFFFAOYSA-N 50036813 CHEMBL10417::{4-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00034a003 10.7270/Q23R0RXB 7909336 Reitz, AB; Bennett, DJ; Blum, PS; Codd, EE; Maryanoff, CA; Ortegon, ME; Renzi, MJ; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10342149 103944454 CHEMBL10417 ZINC13600954 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055129 Oc1cccc2[C@H]3[C@@H](CCc12)NCc1ccccc31 InChI=1S/C17H17NO/c19-16-7-3-6-14-13(16)8-9-15-17(14)12-5-2-1-4-11(12)10-18-15/h1-7,15,17-19H,8-10H2/t15-,17+/m1/s1 ZVYYLBROTSFWHI-WBVHZDCISA-N 50035643 (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridin-9-ol::CHEMBL320481 D(2) dopamine receptor Rattus norvegicus 2000 ChEMBL 10.1021/jm00002a013 10.7270/Q2057DZH 7830274 Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264175 103943654 CHEMBL320481 ZINC13740248 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055131 CN1Cc2ccccc2[C@H]2[C@H]1CCc1c(O)c(O)ccc21 InChI=1S/C18H19NO2/c1-19-10-11-4-2-3-5-12(11)17-13-7-9-16(20)18(21)14(13)6-8-15(17)19/h2-5,7,9,15,17,20-21H,6,8,10H2,1H3/t15-,17-/m1/s1 GFOJCADGVHYVJC-NVXWUHKLSA-N 50035644 (6aR,12bR)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-9,10-diol::CHEMBL418791::Ro-21-7767 D(2) dopamine receptor Rattus norvegicus 121 ChEMBL 10.1021/jm00002a013 10.7270/Q2057DZH 7830274 Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11778475 103943655 CHEMBL418791 ZINC13604045 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055132 Oc1ccc2CC[C@H]3NCc4ccccc4[C@H]3c2c1 InChI=1S/C17H17NO/c19-13-7-5-11-6-8-16-17(15(11)9-13)14-4-2-1-3-12(14)10-18-16/h1-5,7,9,16-19H,6,8,10H2/t16-,17+/m1/s1 KJAGKRRPTJZCHT-SJORKVTESA-N 50035646 (6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridin-11-ol::CHEMBL326781 D(2) dopamine receptor Rattus norvegicus 15500 ChEMBL 10.1021/jm00002a013 10.7270/Q2057DZH 7830274 Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035646&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264176 103943657 CHEMBL326781 ZINC12355958 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055134 Oc1ccc2CC[C@H]3NCc4ccccc4[C@@H]3c2c1 InChI=1S/C17H17NO/c19-13-7-5-11-6-8-16-17(15(11)9-13)14-4-2-1-3-12(14)10-18-16/h1-5,7,9,16-19H,6,8,10H2/t16-,17-/m1/s1 KJAGKRRPTJZCHT-IAGOWNOFSA-N 50035647 (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridin-11-ol::CHEMBL113477 D(2) dopamine receptor Rattus norvegicus 631 ChEMBL 10.1021/jm00002a013 10.7270/Q2057DZH 7830274 Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992356 103943658 CHEMBL113477 ZINC26979381 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055138 CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1ccc(O)cc21 InChI=1S/C20H23NO/c1-2-11-21-13-15-5-3-4-6-17(15)20-18-12-16(22)9-7-14(18)8-10-19(20)21/h3-7,9,12,19-20,22H,2,8,10-11,13H2,1H3/t19-,20-/m1/s1 PSNSPLFQISPDFU-WOJBJXKFSA-N 50035649 (6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridin-11-ol::CHEMBL321040 D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm00002a013 10.7270/Q2057DZH 7830274 Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10424479 103943660 CHEMBL321040 ZINC13740247 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055140 CN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(Br)c(O)cc21 InChI=1S/C18H18BrNO/c1-20-10-12-4-2-3-5-13(12)18-14-9-17(21)15(19)8-11(14)6-7-16(18)20/h2-5,8-9,16,18,21H,6-7,10H2,1H3/t16-,18-/m1/s1 LGYJRJSIABNMNK-SJLPKXTDSA-N 50035645 (6aR,12bS)-10-Bromo-6-methyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridin-11-ol::CHEMBL68680 D(2) dopamine receptor Rattus norvegicus 3000 ChEMBL 10.1021/jm00002a013 10.7270/Q2057DZH 7830274 Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035645&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10043093 103943656 CHEMBL68680 ZINC26274927 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055141 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Rattus norvegicus 107 ChEMBL 10.1021/jm00002a013 10.7270/Q2057DZH 7830274 Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055142 Oc1cccc2[C@@H]3[C@@H](CCc12)NCc1ccccc31 InChI=1S/C17H17NO/c19-16-7-3-6-14-13(16)8-9-15-17(14)12-5-2-1-4-11(12)10-18-15/h1-7,15,17-19H,8-10H2/t15-,17-/m1/s1 ZVYYLBROTSFWHI-NVXWUHKLSA-N 50035650 (6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridin-9-ol::CHEMBL113053 D(2) dopamine receptor Rattus norvegicus 532 ChEMBL 10.1021/jm00002a013 10.7270/Q2057DZH 7830274 Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035650&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264174 103943661 CHEMBL113053 ZINC13740246 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055143 CN1Cc2ccccc2[C@H]2[C@H]1CCc1ccc(O)cc21 InChI=1S/C18H19NO/c1-19-11-13-4-2-3-5-15(13)18-16-10-14(20)8-6-12(16)7-9-17(18)19/h2-6,8,10,17-18,20H,7,9,11H2,1H3/t17-,18-/m1/s1 YMKPESJKPYHAOX-QZTJIDSGSA-N 50035651 (6aR,12bS)-6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridin-11-ol::CHEMBL111348 D(2) dopamine receptor Rattus norvegicus 359 ChEMBL 10.1021/jm00002a013 10.7270/Q2057DZH 7830274 Brewster, WK; Nichols, DE; Watts, VJ; Riggs, RM; Mottola, D; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264849 103943662 CHEMBL111348 ZINC26959969 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50054131 CN1CCN(CC1)C1Cn2cccc2Sc2ccc(Cl)cc12 InChI=1S/C17H20ClN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11,15H,7-10,12H2,1H3 YQXNPUPTPJOJOV-UHFFFAOYSA-N 50066910 (+/-)7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(R)-(-)7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(S)-(+)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene(ST1460)::7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL120512 D(2) dopamine receptor Rattus norvegicus 49.6 ChEMBL 10.1021/jm9706832 10.7270/Q2JH3MVJ 9748351 Campiani, G; Nacci, V; Bechelli, S; Ciani, SM; Garofalo, A; Fiorini, I; Wikstrom, H; de Boer, P; Liao, Y; Tepper, PG; Cagnotto, A; Mennini, T Universita' di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066910&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9884087 103961446 CHEMBL120512 ZINC22925209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055260 OCc1coc2cc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)ccc2c1=O InChI=1S/C25H25FN2O5/c26-18-2-4-20-23(12-18)33-27-24(20)16-6-9-28(10-7-16)8-1-11-31-19-3-5-21-22(13-19)32-15-17(14-29)25(21)30/h2-5,12-13,15-16,29H,1,6-11,14H2 ICAXEUYZCLRXKY-UHFFFAOYSA-N 50072822 7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-hydroxymethyl-chromen-4-one::CHEMBL151475 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3037308 103966424 CHEMBL151475 ZINC01893112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055261 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 9.8 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055264 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50055265 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057427 O=C(NCCN1CCN(Cc2ccccc2)CC1)c1nsc2ccccc12 InChI=1S/C21H24N4OS/c26-21(20-18-8-4-5-9-19(18)27-23-20)22-10-11-24-12-14-25(15-13-24)16-17-6-2-1-3-7-17/h1-9H,10-16H2,(H,22,26) BDULTTOIULVIHN-UHFFFAOYSA-N 50036886 Benzo[d]isothiazole-3-carboxylic acid [2-(4-benzyl-piperazin-1-yl)-ethyl]-amide::CHEMBL307037 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036886&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11740523 103944527 CHEMBL307037 ZINC22937382 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057429 Fc1ccc(cc1)C(=O)C1CCN(CCNC(=O)c2nsc3ccccc23)CC1 InChI=1S/C22H22FN3O2S/c23-17-7-5-15(6-8-17)21(27)16-9-12-26(13-10-16)14-11-24-22(28)20-18-3-1-2-4-19(18)29-25-20/h1-8,16H,9-14H2,(H,24,28) DQVSZMGSVSMZTD-UHFFFAOYSA-N 50036887 Benzo[d]isothiazole-3-carboxylic acid {2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-ethyl}-amide::CHEMBL309046 D(2) dopamine receptor Rattus norvegicus 285.6 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036887&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742358 103944528 CHEMBL309046 ZINC12356306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057430 CN(CCCN1CCC(CC1)C(=O)c1ccc(F)cc1)C(=O)c1noc2ccccc12 InChI=1S/C24H26FN3O3/c1-27(24(30)22-20-5-2-3-6-21(20)31-26-22)13-4-14-28-15-11-18(12-16-28)23(29)17-7-9-19(25)10-8-17/h2-3,5-10,18H,4,11-16H2,1H3 JPOVKHZRJJFBHM-UHFFFAOYSA-N 50036885 Benzo[d]isoxazole-3-carboxylic acid {3-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-propyl}-methyl-amide::CHEMBL74160 D(2) dopamine receptor Rattus norvegicus 2377.9 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10477389 103944526 CHEMBL74160 ZINC12356399 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057431 COc1ccccc1N1CCN(CCNC(=O)c2nsc3ccccc23)CC1 InChI=1S/C21H24N4O2S/c1-27-18-8-4-3-7-17(18)25-14-12-24(13-15-25)11-10-22-21(26)20-16-6-2-5-9-19(16)28-23-20/h2-9H,10-15H2,1H3,(H,22,26) FXWOSRWSZZCAGJ-UHFFFAOYSA-N 50036881 Benzo[d]isothiazole-3-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL312139 D(2) dopamine receptor Rattus norvegicus 283 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036881&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3074422 103944522 CHEMBL312139 ZINC53127457 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057434 CN(CCN1CCC(CC1)C(=O)c1ccc(F)cc1)C(=O)c1nsc2ccccc12 InChI=1S/C23H24FN3O2S/c1-26(23(29)21-19-4-2-3-5-20(19)30-25-21)14-15-27-12-10-17(11-13-27)22(28)16-6-8-18(24)9-7-16/h2-9,17H,10-15H2,1H3 UCKJTPKYDOVULT-UHFFFAOYSA-N 50036888 Benzo[d]isothiazole-3-carboxylic acid {2-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-ethyl}-methyl-amide::CHEMBL77992 D(2) dopamine receptor Rattus norvegicus 584.9 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10365091 103944529 CHEMBL77992 ZINC13737882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057436 CN(CCCCN1CCN(CC1)c1csc2cc(F)ccc12)C(=O)c1noc2ccccc12 InChI=1S/C25H27FN4O2S/c1-28(25(31)24-20-6-2-3-7-22(20)32-27-24)10-4-5-11-29-12-14-30(15-13-29)21-17-33-23-16-18(26)8-9-19(21)23/h2-3,6-9,16-17H,4-5,10-15H2,1H3 HTCUAKYQUZVIQU-UHFFFAOYSA-N 50036892 Benzo[d]isoxazole-3-carboxylic acid {4-[4-(6-fluoro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-methyl-amide::CHEMBL76406 D(2) dopamine receptor Rattus norvegicus 925.9 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036892&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9981993 103944533 CHEMBL76406 ZINC03804610 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057442 CN(CCCCN1CCN(CC1)c1nsc2ccccc12)C(=O)c1nsc2ccccc12 InChI=1S/C24H27N5OS2/c1-27(24(30)22-18-8-2-4-10-20(18)31-25-22)12-6-7-13-28-14-16-29(17-15-28)23-19-9-3-5-11-21(19)32-26-23/h2-5,8-11H,6-7,12-17H2,1H3 AKAGMBZAYKLABH-UHFFFAOYSA-N 50036889 Benzo[d]isothiazole-3-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-methyl-amide::CHEMBL75670 D(2) dopamine receptor Rattus norvegicus 208 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036889&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3073072 103944530 CHEMBL75670 ZINC03804600 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057448 COc1ccccc1N1CCN(CCCCNC(=O)c2nsc3ccccc23)CC1 InChI=1S/C23H28N4O2S/c1-29-20-10-4-3-9-19(20)27-16-14-26(15-17-27)13-7-6-12-24-23(28)22-18-8-2-5-11-21(18)30-25-22/h2-5,8-11H,6-7,12-17H2,1H3,(H,24,28) IQFSIQRNTBHQDE-UHFFFAOYSA-N 50036897 Benzo[d]isothiazole-3-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL311383 D(2) dopamine receptor Rattus norvegicus 271 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036897&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9979791 103944538 CHEMBL311383 ZINC12356353 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057451 CN(CCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)c1noc2ccccc12 InChI=1S/C23H23FN4O3/c1-27(23(29)22-17-4-2-3-5-19(17)30-26-22)12-13-28-10-8-15(9-11-28)21-18-7-6-16(24)14-20(18)31-25-21/h2-7,14-15H,8-13H2,1H3 FIVMAKXHQYXYSA-UHFFFAOYSA-N 50036894 Benzo[d]isoxazole-3-carboxylic acid {2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-methyl-amide::CHEMBL76132 D(2) dopamine receptor Rattus norvegicus 197 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036894&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10070854 103944535 CHEMBL76132 ZINC13737885 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057453 CC(C)N(CCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)c1noc2ccccc12 InChI=1S/C25H27FN4O3/c1-16(2)30(25(31)24-19-5-3-4-6-21(19)32-28-24)14-13-29-11-9-17(10-12-29)23-20-8-7-18(26)15-22(20)33-27-23/h3-8,15-17H,9-14H2,1-2H3 HEAHUWCNJIVAHV-UHFFFAOYSA-N 50036895 Benzo[d]isoxazole-3-carboxylic acid {2-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-isopropyl-amide::CHEMBL75379 D(2) dopamine receptor Rattus norvegicus 203.4 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036895&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10253232 103944536 CHEMBL75379 ZINC13737883 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50057455 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 1610 ChEMBL 10.1021/jm00041a009 10.7270/Q2QF8RXV 7914536 Hrib, NJ; Jurcak, JG; Burgher, KL; Conway, PG; Hartman, HB; Kerman, LL; Roehr, JE; Woods, AT Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059705 CCCN(C\C=C\I)C1CCc2ccc(O)cc2C1 InChI=1S/C16H22INO/c1-2-9-18(10-3-8-17)15-6-4-13-5-7-16(19)12-14(13)11-15/h3,5,7-8,12,15,19H,2,4,6,9-11H2,1H3/b8-3+ RTMIJLQPWFKAFE-FPYGCLRLSA-N 50038276 (R,S) 7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::7-[((E)-3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::7-[(3-Iodo-allyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL110239 D(2) dopamine receptor Rattus norvegicus 265 ChEMBL 10.1021/jm00062a025 10.7270/Q2F47PRT 8098771 Foulon, C; Kung, MP; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038276&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6305587 103945713 64137 CHEMBL110239 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058762 C(C1CCC=C(C1)c1ccccc1)N1CCN(CC1)c1ncccn1 InChI=1S/C21H26N4/c1-2-7-19(8-3-1)20-9-4-6-18(16-20)17-24-12-14-25(15-13-24)21-22-10-5-11-23-21/h1-3,5,7-11,18H,4,6,12-17H2 LZUOLMQBKILJRQ-UHFFFAOYSA-N 50037667 2-[4-(3-Phenyl-cyclohex-3-enylmethyl)-piperazin-1-yl]-pyrimidine::CHEMBL119191 D(2) dopamine receptor Rattus norvegicus 354 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037667&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10246306 103945177 CHEMBL119191 ZINC12356147 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058764 C(C1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1cccs1 InChI=1S/C22H25NS/c1-2-7-19(8-3-1)21-9-4-6-18(16-21)17-23-13-11-20(12-14-23)22-10-5-15-24-22/h1-3,5,7-11,15,18H,4,6,12-14,16-17H2 RDVUGHRYXIWMDD-UHFFFAOYSA-N 50037668 1-(3-Phenyl-cyclohex-3-enylmethyl)-4-thiophen-2-yl-1,2,3,6-tetrahydro-pyridine::CHEMBL451189 D(2) dopamine receptor Rattus norvegicus 170 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037668&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9974231 103945178 CHEMBL451189 ZINC13738843 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058765 Fc1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 InChI=1S/C24H26FN/c25-24-11-9-21(10-12-24)23-8-4-5-19(17-23)18-26-15-13-22(14-16-26)20-6-2-1-3-7-20/h1-3,6-13,19H,4-5,14-18H2/t19-/m1/s1 ZWUNBPHDMGCKGM-LJQANCHMSA-N 50037669 1-[(R)-3-(4-Fluoro-phenyl)-cyclohex-3-enylmethyl]-4-phenyl-1,2,3,6-tetrahydro-pyridine::CHEMBL118219 D(2) dopamine receptor Rattus norvegicus 76 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10043309 103945179 CHEMBL118219 ZINC13738850 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058767 COc1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 InChI=1S/C25H29NO/c1-27-25-12-10-22(11-13-25)24-9-5-6-20(18-24)19-26-16-14-23(15-17-26)21-7-3-2-4-8-21/h2-4,7-14,20H,5-6,15-19H2,1H3/t20-/m1/s1 JCNGPOQBWNDDLN-HXUWFJFHSA-N 50037671 1-[(R)-3-(4-Methoxy-phenyl)-cyclohex-3-enylmethyl]-4-phenyl-1,2,3,6-tetrahydro-pyridine::CHEMBL119273 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037671&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9975744 103945181 CHEMBL119273 ZINC13738851 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058768 Cc1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 InChI=1S/C25H29N/c1-20-10-12-23(13-11-20)25-9-5-6-21(18-25)19-26-16-14-24(15-17-26)22-7-3-2-4-8-22/h2-4,7-14,21H,5-6,15-19H2,1H3/t21-/m1/s1 FORCDIAATKJODX-OAQYLSRUSA-N 50037672 4-Phenyl-1-((R)-3-p-tolyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL324085 D(2) dopamine receptor Rattus norvegicus 328.0 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10337518 103945182 CHEMBL324085 ZINC13738848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058772 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058774 C(C1CCC=C(C1)c1ccccc1)N1CCN(CC1)c1ccccn1 InChI=1S/C22H27N3/c1-2-8-20(9-3-1)21-10-6-7-19(17-21)18-24-13-15-25(16-14-24)22-11-4-5-12-23-22/h1-5,8-12,19H,6-7,13-18H2 AWOGKNNAUOHEDQ-UHFFFAOYSA-N 50037674 1-(3-Phenyl-cyclohex-3-enylmethyl)-4-pyridin-2-yl-piperazine::CHEMBL116205 D(2) dopamine receptor Rattus norvegicus 141 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037674&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9797733 103945184 CHEMBL116205 ZINC13738845 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058775 Clc1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 InChI=1S/C24H26ClN/c25-24-11-9-21(10-12-24)23-8-4-5-19(17-23)18-26-15-13-22(14-16-26)20-6-2-1-3-7-20/h1-3,6-13,19H,4-5,14-18H2/t19-/m1/s1 ITANASSNEOXAJO-LJQANCHMSA-N 50037675 1-[(R)-3-(4-Chloro-phenyl)-cyclohex-3-enylmethyl]-4-phenyl-1,2,3,6-tetrahydro-pyridine::CHEMBL118721 D(2) dopamine receptor Rattus norvegicus 4634 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037675&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10316683 103945185 CHEMBL118721 ZINC13738849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058777 C(C1CCCC(=C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-12,14,18,20H,7-8,13,15-17,19H2 JWVXDQBQUCCGDC-UHFFFAOYSA-N 50037673 4-Phenyl-1-(3-phenyl-cyclohex-2-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL119339 D(2) dopamine receptor Rattus norvegicus 420 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037673&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10087982 103945183 CHEMBL119339 ZINC13738837 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058780 C(C1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-9-21(10-4-1)23-14-16-25(17-15-23)19-20-8-7-13-24(18-20)22-11-5-2-6-12-22/h1-6,9-14,20H,7-8,15-19H2 XBGWTWPYCTZIIE-UHFFFAOYSA-N 50037670 4-Phenyl-1-(3-phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL117527 D(2) dopamine receptor Rattus norvegicus 112 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037670&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10449274 103945180 CHEMBL117527 ZINC13738833 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058781 C(C1CCCC=C1c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-9-20(10-4-1)21-15-17-25(18-16-21)19-23-13-7-8-14-24(23)22-11-5-2-6-12-22/h1-6,9-12,14-15,23H,7-8,13,16-19H2 VCJROJRYERJGMQ-UHFFFAOYSA-N 50037676 4-Phenyl-1-(2-phenyl-cyclohex-2-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL120197 D(2) dopamine receptor Rattus norvegicus 3936.0 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037676&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10042233 103945186 CHEMBL120197 ZINC13738832 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058785 FC(F)(F)c1ccc(cc1)C1=CCC[C@@H](CN2CCC(=CC2)c2ccccc2)C1 InChI=1S/C25H26F3N/c26-25(27,28)24-11-9-21(10-12-24)23-8-4-5-19(17-23)18-29-15-13-22(14-16-29)20-6-2-1-3-7-20/h1-3,6-13,19H,4-5,14-18H2/t19-/m1/s1 DPMBHMXOOOYZNH-LJQANCHMSA-N 50037678 4-Phenyl-1-[(R)-3-(4-trifluoromethyl-phenyl)-cyclohex-3-enylmethyl]-1,2,3,6-tetrahydro-pyridine::CHEMBL119575 D(2) dopamine receptor Rattus norvegicus 2554 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037678&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10250204 103945188 CHEMBL119575 ZINC13738852 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058787 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.86 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058788 C(CN1CCC(=CC1)c1ccccc1)C1CCC=C(C1)c1ccccc1 InChI=1S/C25H29N/c1-3-9-22(10-4-1)24-15-18-26(19-16-24)17-14-21-8-7-13-25(20-21)23-11-5-2-6-12-23/h1-6,9-13,15,21H,7-8,14,16-20H2 YTKUTEYPYBMYSY-UHFFFAOYSA-N 50037679 4-Phenyl-1-[2-(3-phenyl-cyclohex-3-enyl)-ethyl]-1,2,3,6-tetrahydro-pyridine::CHEMBL116261 D(2) dopamine receptor Rattus norvegicus 635 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10382848 103945189 CHEMBL116261 ZINC13738841 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058789 C(C1CCC(=CC1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C24H27N/c1-3-7-21(8-4-1)23-13-11-20(12-14-23)19-25-17-15-24(16-18-25)22-9-5-2-6-10-22/h1-10,13,15,20H,11-12,14,16-19H2 VFSHTRBJQOOJNL-UHFFFAOYSA-N 50037681 4-Phenyl-1-(4-phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL333053 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037681&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9973857 103945191 CHEMBL333053 ZINC13738835 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058790 C1CC(CC(=C1)c1ccccc1)N1CCC(=CC1)c1ccccc1 InChI=1S/C23H25N/c1-3-8-19(9-4-1)21-14-16-24(17-15-21)23-13-7-12-22(18-23)20-10-5-2-6-11-20/h1-6,8-12,14,23H,7,13,15-18H2 KYNACDPIFPBEAN-UHFFFAOYSA-N 50037677 4-Phenyl-1-(3-phenyl-cyclohex-3-enyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL118461 D(2) dopamine receptor Rattus norvegicus 9207 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037677&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10448423 103945187 CHEMBL118461 ZINC13738839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058793 C(C1CCC=C(C1)c1ccccc1)N1CCN(CC1)c1ccccc1 InChI=1S/C23H28N2/c1-3-9-21(10-4-1)22-11-7-8-20(18-22)19-24-14-16-25(17-15-24)23-12-5-2-6-13-23/h1-6,9-13,20H,7-8,14-19H2 DIIHIBQLKHJDKZ-UHFFFAOYSA-N 50037680 1-Phenyl-4-(3-phenyl-cyclohex-3-enylmethyl)-piperazine::CHEMBL327070 D(2) dopamine receptor Rattus norvegicus 424.0 ChEMBL 10.1021/jm00047a010 10.7270/Q2GT5M68 7932581 Wright, JL; Caprathe, BW; Downing, DM; Glase, SA; Heffner, TG; Jaen, JC; Johnson, SJ; Kesten, SR; MacKenzie, RG; Meltzer, LT Parke-Davis Pharmaceutical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10359439 103945190 CHEMBL327070 ZINC13738847 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061101 CCCN1CCCC(C1)c1cccc(c1)C#N InChI=1S/C15H20N2/c1-2-8-17-9-4-7-15(12-17)14-6-3-5-13(10-14)11-16/h3,5-6,10,15H,2,4,7-9,12H2,1H3 GQRIAOUUYRIMLH-UHFFFAOYSA-N 50041960 (+)-3-(1-Propyl-piperidin-3-yl)-benzonitrile::(-)-3-(1-Propyl-piperidin-3-yl)-benzonitrile::3-(1-Propyl-piperidin-3-yl)-benzonitrile::CHEMBL107492 D(2) dopamine receptor Rattus norvegicus 12600 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5119 103973639 CHEMBL107492 ZINC03785159 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061113 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.700000 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061119 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Rattus norvegicus 70 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061148 CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1 YGHLYBIUVOLKCV-SMDDNHRTSA-N 50041959 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::AJ76(+)::CHEMBL27441 D(2) dopamine receptor Rattus norvegicus 530 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122334 103973638 64117 CHEMBL27441 970 ZINC03995669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061157 CCCN1CCC[C@@H](C1)c1cccc(OS(=O)(=O)C(F)(F)F)c1 InChI=1S/C15H20F3NO3S/c1-2-8-19-9-4-6-13(11-19)12-5-3-7-14(10-12)22-23(20,21)15(16,17)18/h3,5,7,10,13H,2,4,6,8-9,11H2,1H3/t13-/m0/s1 VUEGBGWRCATKQZ-ZDUSSCGKSA-N 50041962 (+)-Trifluoro-methanesulfonic acid 3-(1-propyl-piperidin-3-yl)-phenyl ester::CHEMBL110821 D(2) dopamine receptor Rattus norvegicus 8300 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041962&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654434 103973641 CHEMBL110821 ZINC36093062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058110 CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C#N)c3c2C1 InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3/t16-/m0/s1 ODCNQSRYNGLVNW-INIZCTEOSA-N 50035324 (S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbonitrile::CHEMBL71804 D(2) dopamine receptor Rattus norvegicus 8015 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10379784 103943350 CHEMBL71804 ZINC13738695 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058111 CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3 GKDJCOLVXBCNNK-UHFFFAOYSA-N 50035329 (+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine::CHEMBL65196::Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 156 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035329&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13096730 103943355 CHEMBL65196 ZINC03798326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058113 CCCN(CCC)C1CCc2cc3cc[nH]c3cc2C1 InChI=1S/C18H26N2/c1-3-9-20(10-4-2)17-6-5-14-11-15-7-8-19-18(15)13-16(14)12-17/h7-8,11,13,17,19H,3-6,9-10,12H2,1-2H3 PJRCRPZYNQZZBV-UHFFFAOYSA-N 50037271 CHEMBL305341::Dipropyl-(5,6,7,8-tetrahydro-1H-benzo[f]indol-7-yl)-amine D(2) dopamine receptor Rattus norvegicus 350 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037271&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129733 103944819 CHEMBL305341 ZINC05833126 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058120 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058123 CCCN(CCC)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3 DSEPKSLFXGYPIU-UHFFFAOYSA-N 50035320 (+/-)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL304426 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 178081 103943346 CHEMBL304426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058124 CCCN(CCC)C1CCc2ccc3CCN(C=O)c3c2C1 InChI=1S/C19H28N2O/c1-3-10-20(11-4-2)17-8-7-15-5-6-16-9-12-21(14-22)19(16)18(15)13-17/h5-6,14,17H,3-4,7-13H2,1-2H3 XTSIAWSUYQFEKE-UHFFFAOYSA-N 50037276 8-Dipropylamino-2,3,6,7,8,9-hexahydro-benzo[g]indole-1-carbaldehyde::CHEMBL68523 D(2) dopamine receptor Rattus norvegicus >16000 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037276&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9972037 103944824 CHEMBL68523 ZINC13738707 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058126 CCCN(CCC)C1CCc2ccc3[nH]cc(CC(F)(F)F)c3c2C1 InChI=1S/C20H27F3N2/c1-3-9-25(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-24-18)12-20(21,22)23/h6,8,13,16,24H,3-5,7,9-12H2,1-2H3 LKUMKJQSYINUSG-UHFFFAOYSA-N 50035301 CHEMBL71899::Dipropyl-[1-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl]-amine D(2) dopamine receptor Rattus norvegicus 796 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035301&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10247448 103943327 CHEMBL71899 ZINC13738699 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058128 CCCN(CCC)C1CCc2ccc3c(CC(F)(F)F)c[nH]c3c2C1 InChI=1S/C20H27F3N2/c1-3-9-25(10-4-2)16-7-5-14-6-8-17-15(12-20(21,22)23)13-24-19(17)18(14)11-16/h6,8,13,16,24H,3-5,7,9-12H2,1-2H3 IIDRMPPLCHQZHE-UHFFFAOYSA-N 50037273 CHEMBL110032::Dipropyl-[3-(2,2,2-trifluoro-ethyl)-6,7,8,9-tetrahydro-1H-benzo[g]indol-8-yl]-amine D(2) dopamine receptor Rattus norvegicus 2330 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10428094 103944821 CHEMBL110032 ZINC13738703 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058129 CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m1/s1 DSEPKSLFXGYPIU-MRXNPFEDSA-N 50035303 (R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL71625 D(2) dopamine receptor Rattus norvegicus 382.0 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035303&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10870264 103943329 CHEMBL71625 ZINC03782839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058130 CCCN(CCC)C1CCc2ccc3[nH]cc(C#N)c3c2C1 InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3 ODCNQSRYNGLVNW-UHFFFAOYSA-N 50035326 8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbonitrile::CHEMBL70589 D(2) dopamine receptor Rattus norvegicus 439 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9994674 103943352 CHEMBL70589 ZINC13738694 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058131 CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1 GKDJCOLVXBCNNK-OAHLLOKOSA-N 50035330 CHEMBL302172::Dipropyl-(R)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::R-(+)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10858566 103943356 CHEMBL302172 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058132 CCCN(CCC)C1CCc2ccc3[nH]cc(Cl)c3c2C1 InChI=1S/C18H25ClN2/c1-3-9-21(10-4-2)14-7-5-13-6-8-17-18(15(13)11-14)16(19)12-20-17/h6,8,12,14,20H,3-5,7,9-11H2,1-2H3 AXWVKOPRBOVXMC-UHFFFAOYSA-N 50035306 (1-Chloro-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-dipropyl-amine::CHEMBL303021 D(2) dopamine receptor Rattus norvegicus 317 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035306&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11779840 103943332 CHEMBL303021 ZINC13738697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058133 CCCN(CCC)C1CCc2ccc3c(C=O)c[nH]c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-17-15(13-22)12-20-19(17)18(14)11-16/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3 QKAOUELTNSQJKI-UHFFFAOYSA-N 50037278 8-Dipropylamino-6,7,8,9-tetrahydro-1H-benzo[g]indole-3-carbaldehyde::CHEMBL325837 D(2) dopamine receptor Rattus norvegicus >16000 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10379957 103944826 CHEMBL325837 ZINC13738701 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058135 CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1 GKDJCOLVXBCNNK-HNNXBMFYSA-N 50035307 CHEMBL302171::Dipropyl-(S)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::S-(-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 146 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035307&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10468376 103943333 CHEMBL302171 ZINC13738689 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058138 CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C#N)c3c2C1 InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(12-20)13-21-18/h6,8,13,16,21H,3-5,7,9-11H2,1-2H3/t16-/m1/s1 ODCNQSRYNGLVNW-MRXNPFEDSA-N 50035328 (R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbonitrile::CHEMBL308347 D(2) dopamine receptor Rattus norvegicus 419.0 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035328&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10402263 103943354 CHEMBL308347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058139 CCCN(CCC)[C@@H]1CCc2ccc3[nH]c(cc3c2C1)C#N InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-19-18(17(14)12-16)11-15(13-20)21-19/h6,8,11,16,21H,3-5,7,9-10,12H2,1-2H3/t16-/m1/s1 WDDZPZKGLZNGEH-MRXNPFEDSA-N 50037272 (R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-2-carbonitrile::CHEMBL71920 D(2) dopamine receptor Rattus norvegicus 538 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037272&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9904242 103944820 CHEMBL71920 30 ZINC03792458 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058143 CCCN(CCC)C1CCc2cc3c(C=O)c[nH]c3cc2C1 InChI=1S/C19H26N2O/c1-3-7-21(8-4-2)17-6-5-14-10-18-16(13-22)12-20-19(18)11-15(14)9-17/h10-13,17,20H,3-9H2,1-2H3 UQEPLPAEGWFYQH-UHFFFAOYSA-N 50037277 7-Dipropylamino-5,6,7,8-tetrahydro-1H-benzo[f]indole-3-carbaldehyde::CHEMBL113378 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10379956 103944825 CHEMBL113378 ZINC13738693 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058144 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 1357 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058145 CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m0/s1 DSEPKSLFXGYPIU-INIZCTEOSA-N 50035305 (S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL307786 D(2) dopamine receptor Rattus norvegicus 3592.0 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035305&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948210 103943331 CHEMBL307786 ZINC00005554 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50058149 CCCN(CCC)C1CCc2ccc3CCNc3c2C1 InChI=1S/C18H28N2/c1-3-11-20(12-4-2)16-8-7-14-5-6-15-9-10-19-18(15)17(14)13-16/h5-6,16,19H,3-4,7-13H2,1-2H3 OTEIKDZGZUYQLL-UHFFFAOYSA-N 50037275 (2,3,6,7,8,9-Hexahydro-1H-benzo[g]indol-8-yl)-dipropyl-amine::CHEMBL109268 D(2) dopamine receptor Rattus norvegicus 650 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037275&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10107314 103944823 CHEMBL109268 ZINC13738705 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060299 Fc1ccc(OCCN2CCc3ccccc3C2)c2CC(=O)Nc12 InChI=1S/C19H19FN2O2/c20-16-5-6-17(15-11-18(23)21-19(15)16)24-10-9-22-8-7-13-3-1-2-4-14(13)12-22/h1-6H,7-12H2,(H,21,23) UFPMVMHWBPUCTK-UHFFFAOYSA-N 50077570 4-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-ethoxy]-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL291459 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10592220 103970339 CHEMBL291459 ZINC26162337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060300 Fc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1 InChI=1S/C17H16ClFN2O2/c18-14-5-6-15(13-9-16(22)21-17(13)14)23-8-7-20-10-11-1-3-12(19)4-2-11/h1-6,20H,7-10H2,(H,21,22) LYCHDJRJSBEWKP-UHFFFAOYSA-N 50077599 7-Chloro-4-[2-(4-fluoro-benzylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL59500 D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077599&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10544736 103970368 CHEMBL59500 ZINC29570546 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060329 Ic1ccc(cc1)C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C19H21IN2O/c20-17-8-6-16(7-9-17)19(23)21-18-10-12-22(13-11-18)14-15-4-2-1-3-5-15/h1-9,18H,10-14H2,(H,21,23) HELCSESNNDZLFM-UHFFFAOYSA-N 50038419 CHEMBL50112::N-(1-Benzyl-piperidin-4-yl)-4-iodo-benzamide D(2) dopamine receptor Rattus norvegicus 382.0 ChEMBL 10.1021/jm00038a002 10.7270/Q2VX0FJ7 8021913 John, CS; Vilner, BJ; Bowen, WD George Washington University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038419&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 61V 5HK2 132995 103945793 CHEMBL50112 ZINC01642602 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060336 Ic1ccccc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C19H21IN2O/c20-18-9-5-4-8-17(18)19(23)21-16-10-12-22(13-11-16)14-15-6-2-1-3-7-15/h1-9,16H,10-14H2,(H,21,23) KARHAJNERWKAIT-UHFFFAOYSA-N 50038418 CHEMBL46326::N-(1-Benzyl-piperidin-4-yl)-2-iodo-benzamide D(2) dopamine receptor Rattus norvegicus 63.4 ChEMBL 10.1021/jm00038a002 10.7270/Q2VX0FJ7 8021913 John, CS; Vilner, BJ; Bowen, WD George Washington University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 381254 103945792 CHEMBL46326 ZINC01642601 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060340 Ic1cccc(c1)C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C19H21IN2O/c20-17-8-4-7-16(13-17)19(23)21-18-9-11-22(12-10-18)14-15-5-2-1-3-6-15/h1-8,13,18H,9-12,14H2,(H,21,23) VOIQMSJHUQWNSN-UHFFFAOYSA-N 50038420 CHEMBL539938::N-(1-Benzyl-piperidin-4-yl)-3-iodo-benzamide D(2) dopamine receptor Rattus norvegicus 24.8 ChEMBL 10.1021/jm00038a002 10.7270/Q2VX0FJ7 8021913 John, CS; Vilner, BJ; Bowen, WD George Washington University Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038420&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 381255 103945794 CHEMBL539938 ZINC01642603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061396 CCCN(CCC)C1CCc2c(C1)cccc2OS(=O)(=O)C(F)(F)F InChI=1S/C17H24F3NO3S/c1-3-10-21(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)24-25(22,23)17(18,19)20/h5-7,14H,3-4,8-12H2,1-2H3 GQWGKLIYDKGPRT-UHFFFAOYSA-N 50042341 CHEMBL324750::Trifluoro-methanesulfonic acid 6-dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl ester D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14977563 103973947 CHEMBL324750 ZINC36187800 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061397 CCCN(CCC)C1CCc2cc(OS(=O)(=O)C(F)(F)F)ccc2C1 InChI=1S/C17H24F3NO3S/c1-3-9-21(10-4-2)15-7-5-14-12-16(8-6-13(14)11-15)24-25(22,23)17(18,19)20/h6,8,12,15H,3-5,7,9-11H2,1-2H3 BGPASGZLQNQAAZ-UHFFFAOYSA-N 50042339 CHEMBL442203::Trifluoro-methanesulfonic acid 6-dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-yl ester D(2) dopamine receptor Rattus norvegicus 99 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14977564 103973945 CHEMBL442203 ZINC36093064 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061400 CCN1CCC[C@H]1CN1Cc2ccc(Cl)cc2C1=O InChI=1S/C15H19ClN2O/c1-2-17-7-3-4-13(17)10-18-9-11-5-6-12(16)8-14(11)15(18)19/h5-6,8,13H,2-4,7,9-10H2,1H3/t13-/m0/s1 SHAZWFJAAHPGKJ-ZDUSSCGKSA-N 50456198 CHEMBL2111762 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm00074a023 10.7270/Q2S75GZD 7901417 Norman, MH; Kelley, JL; Hollingsworth, EB Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456198&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10221298 225147114 CHEMBL2111762 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060429 NC1CC(c2ccccc2)c2cc(O)c(O)cc2C1 InChI=1S/C16H17NO2/c17-12-6-11-7-15(18)16(19)9-14(11)13(8-12)10-4-2-1-3-5-10/h1-5,7,9,12-13,18-19H,6,8,17H2 SSUNCBAILFPJRJ-UHFFFAOYSA-N 50040280 CHEMBL538263::cis-7-Amino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide::trans-7-Amino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide D(2) dopamine receptor Rattus norvegicus >30000 ChEMBL 10.1021/jm00069a013 10.7270/Q2C53MGM 8102651 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15657205 103972340 CHEMBL538263 ZINC26572113 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059508 CCCN1CC[C@@H]2[C@H]1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3/t13-,14-/m1/s1 HPUKPOAWHHZLIX-ZIAGYGMSSA-N 50034327 (3aR,9bS) 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-9-methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aS,9bR) 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL284585 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10332127 103942528 CHEMBL284585 ZINC13826502 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059510 COc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m1/s1 ZRAGXRIXRXDXCR-HIFRSBDPSA-N 50453387 CHEMBL566970 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453387&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10060349 225145936 CHEMBL566970 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059512 COc1cccc2CCC3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3 VRRJFCMGNMFNOE-UHFFFAOYSA-N 50455993 CHEMBL273412 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18988817 225146909 CHEMBL273412 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059516 Oc1cccc2CCC3C(CCN3CC=C)c12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h2-5,12-13,17H,1,6-10H2 NLAWPJROLJRPAW-UHFFFAOYSA-N 50455997 CHEMBL10048 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455997&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266651 225146913 CHEMBL10048 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059517 COc1cccc2CC3C(CCN3CC=C)Cc12 InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3 ASEDQXVCNPLEIO-UHFFFAOYSA-N 50455998 CHEMBL2114338 D(2) dopamine receptor Rattus norvegicus 429 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455998&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18988815 225146914 CHEMBL2114338 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059519 COc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13-,14-/m1/s1 VRRJFCMGNMFNOE-ZIAGYGMSSA-N 50034330 (3aR,9bS) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-3-allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aS,9bR) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL26118 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105844 103942531 CHEMBL26118 ZINC03790769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059521 CCCN1CCC2Cc3c(O)cccc3CC12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3 DYVLYWKEJHHXOH-UHFFFAOYSA-N 50455999 CHEMBL2114337 D(2) dopamine receptor Rattus norvegicus 296 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455999&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18988835 225146915 CHEMBL2114337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059538 Oc1cccc2C3CCN(CC=C)C3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50040159 (Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL10289 D(2) dopamine receptor Rattus norvegicus 198 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040159&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266636 103972219 CHEMBL10289 ZINC13826535 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059541 Oc1cccc2[C@H]3CCN(CC=C)[C@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12-,14+/m1/s1 MHHLELSXRBTNRD-OCCSQVGLSA-N 50455996 CHEMBL566133 D(2) dopamine receptor Rattus norvegicus 259 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14944887 225146912 CHEMBL566133 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059544 CCCN1CC[C@H]2[C@@H]1CCc1c(OC)cccc21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15+/m1/s1 VUKJBNUKLLGULS-HIFRSBDPSA-N 50455995 CHEMBL2051973 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70694687 225146911 CHEMBL2051973 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50059545 CCCN1CC[C@@H]2[C@@H]1CCc1c(OC)cccc21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m0/s1 VUKJBNUKLLGULS-ZFWWWQNUSA-N 50455994 CHEMBL2051769 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70694683 225146910 CHEMBL2051769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060700 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=S)CC2)c2ccc(Cl)cc12 InChI=1S/C25H30ClFN4S/c26-19-4-7-21-23(16-19)22(18-2-5-20(27)6-3-18)17-24(21)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) ADJUKJVEVGOWPC-UHFFFAOYSA-N 50368668 CHEMBL1788128 D(2) dopamine receptor Rattus norvegicus 33.0 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368668&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037250 160847770 CHEMBL1788128 ZINC22940833 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060705 Cl.Cl.OCCN1CCN(CC1)C1CC(c2cc(Cl)ccc12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2O.2ClH/c22-16-3-6-18-20(13-16)19(15-1-4-17(23)5-2-15)14-21(18)25-9-7-24(8-10-25)11-12-26;;/h1-6,13,19,21,26H,7-12,14H2;2*1H DXUBHXOFLIXZOM-UHFFFAOYSA-N 50045636 3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-oxazolidin-2-one dihydrochloride::CHEMBL2111567 D(2) dopamine receptor Rattus norvegicus 6300 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71457959 103976512 CHEMBL2111567 ZINC26669872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060707 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCOC3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C24H27ClFN3O2.2ClH/c25-18-3-6-20-22(15-18)21(17-1-4-19(26)5-2-17)16-23(20)28-10-7-27(8-11-28)9-12-29-13-14-31-24(29)30;;/h1-6,15,21,23H,7-14,16H2;2*1H NBPOREIXFPLMGE-UHFFFAOYSA-N 50456158 CHEMBL2447981 D(2) dopamine receptor Rattus norvegicus 550 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73354163 225147074 CHEMBL2447981 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061806 COc1cccc(C(=O)NC2CC3CCCC(C2)N3Cc2ccccc2)c1OC InChI=1S/C24H30N2O3/c1-28-22-13-7-12-21(23(22)29-2)24(27)25-18-14-19-10-6-11-20(15-18)26(19)16-17-8-4-3-5-9-17/h3-5,7-9,12-13,18-20H,6,10-11,14-16H2,1-2H3,(H,25,27) ZEPBXECUPSIRLM-UHFFFAOYSA-N 50456208 CHEMBL2112605 D(2) dopamine receptor Rattus norvegicus 0.038000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456208&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3068195 225147124 CHEMBL2112605 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061807 COc1cccc(C(=O)NC2CC3CCCC(C2)N3Cc2ccc(F)cc2)c1OC InChI=1S/C24H29FN2O3/c1-29-22-8-4-7-21(23(22)30-2)24(28)26-18-13-19-5-3-6-20(14-18)27(19)15-16-9-11-17(25)12-10-16/h4,7-12,18-20H,3,5-6,13-15H2,1-2H3,(H,26,28) VGOAURMKLDUSEO-UHFFFAOYSA-N 50456207 CHEMBL2112607 D(2) dopamine receptor Rattus norvegicus 0.028000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50456207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50456207&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23277137 225147123 CHEMBL2112607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061808 COc1cc(N)c(Cl)cc1C(=O)N[C@H]1C[C@@H]2CCC[C@H](C1)N2Cc1ccc(F)cc1 InChI=1S/C23H27ClFN3O2/c1-30-22-12-21(26)20(24)11-19(22)23(29)27-16-9-17-3-2-4-18(10-16)28(17)13-14-5-7-15(25)8-6-14/h5-8,11-12,16-18H,2-4,9-10,13,26H2,1H3,(H,27,29)/t16-,17-,18+ PSOJUYFGYMSZHW-NNZMDNLPSA-N 84746 BRL 34778::BRL-34778 D(2) dopamine receptor Rattus norvegicus >10 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84746&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57339832 136350846 ZINC13834042 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064092 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 3500 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064093 CCCN1Cc2c(C)cccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 InChI=1S/C21H25NO2/c1-3-9-22-12-17-13(2)5-4-6-15(17)21-16-11-20(24)19(23)10-14(16)7-8-18(21)22/h4-6,10-11,18,21,23-24H,3,7-9,12H2,1-2H3/t18-,21-/m1/s1 IURHNFGBYOFFDB-WIYYLYMNSA-N 50032516 (6aR,12bS)-4-Methyl-6-propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-4-methyl-6-propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(4-MNP-DHX)::CHEMBL104141 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10314127 103941014 CHEMBL104141 ZINC13478192 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064094 Oc1cc2CCNCC(c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2 JUDKOGFHZYMDMF-UHFFFAOYSA-N 50004923 (+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514 D(2) dopamine receptor Rattus norvegicus 18000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1242 103918470 CHEMBL505308CHEMBL286080CHEMBL542700 935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064095 Oc1cc2[C@H](CN(CC=C)CCc2c(Br)c1O)c1ccccc1 InChI=1S/C19H20BrNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m1/s1 KKZGFVAZUKHFAC-MRXNPFEDSA-N 50004921 (R)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)6-Br-APB)::CHEMBL34095::R-(+)6-Br-APD3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus 1600 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10452020 103918468 CHEMBL34095 ZINC02530683 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064096 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 267000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064097 Oc1cc2[C@H](C[NH2+]CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2/p+1/t13-/m1/s1 GHWJEDJMOVUXEC-CYBMUJFWSA-O 50067726 (R)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(6-Cl-PB)::SKF 81297 D(2) dopamine receptor Rattus norvegicus 3000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332751 103962153 ZINC03783980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064098 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064099 [NH3+][C@@H]1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2/p+1/t8-/m1/s1 ASXGAOFCKGHGMF-MRVPVSSYSA-O 50091032 6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl-ammonium(R(+)ADTN)::Aminotetralin-6,7-dihydroxy-(+) D(2) dopamine receptor Rattus norvegicus 450 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332855 103989453 ZINC03872369 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064100 [NH3+][C@@H]1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2/p+1/t8-/m1/s1 ASXGAOFCKGHGMF-MRVPVSSYSA-O 50091032 6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl-ammonium(R(+)ADTN)::Aminotetralin-6,7-dihydroxy-(+) D(2) dopamine receptor Rattus norvegicus 17000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332855 103989453 ZINC03872369 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064101 Oc1cc2[C@H](C[NH2+]CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2/p+1/t13-/m1/s1 GHWJEDJMOVUXEC-CYBMUJFWSA-O 50067726 (R)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(6-Cl-PB)::SKF 81297 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332751 103962153 ZINC03783980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064102 CCCN1Cc2c(C)cccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 InChI=1S/C21H25NO2/c1-3-9-22-12-17-13(2)5-4-6-15(17)21-16-11-20(24)19(23)10-14(16)7-8-18(21)22/h4-6,10-11,18,21,23-24H,3,7-9,12H2,1-2H3/t18-,21-/m1/s1 IURHNFGBYOFFDB-WIYYLYMNSA-N 50032516 (6aR,12bS)-4-Methyl-6-propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-4-methyl-6-propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(4-MNP-DHX)::CHEMBL104141 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10314127 103941014 CHEMBL104141 ZINC13478192 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064103 CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18+/m0/s1 BKRGVLQUQGGVSM-KBXCAEBGSA-N 50056445 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea::CHEMBL157138::N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea::lisuride::lisuride, (S) D(2) dopamine receptor Rattus norvegicus 0.30 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search H8G 7WC7,7UM6,6DRX 28864 103952701 51164 CHEMBL157138 DB00589 43 ZINC03831001 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064104 CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1 BLYMJBIZMIGWFK-OAHLLOKOSA-N 50054067 (2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium(R(+)7OH-DPAT)::(R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol.HCl::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL301559 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603867 103950725 CHEMBL301559 ZINC03870310 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064105 CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18+/m0/s1 BKRGVLQUQGGVSM-KBXCAEBGSA-N 50056445 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea::CHEMBL157138::N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea::lisuride::lisuride, (S) D(2) dopamine receptor Rattus norvegicus 2.3 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search H8G 7WC7,7UM6,6DRX 28864 103952701 51164 CHEMBL157138 DB00589 43 ZINC03831001 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064106 CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1 BLYMJBIZMIGWFK-OAHLLOKOSA-N 50054067 (2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium(R(+)7OH-DPAT)::(R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol.HCl::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL301559 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603867 103950725 CHEMBL301559 ZINC03870310 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064107 COc1cc(CC[NH3+])ccc1O InChI=1S/C9H13NO2/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,11H,4-5,10H2,1H3/p+1 DIVQKHQLANKJQO-UHFFFAOYSA-O 50091035 2-(4-Hydroxy-3-methoxy-phenyl)-ethyl-ammonium(3-methoxytyramine)::3-O-methyldopamine D(2) dopamine receptor Rattus norvegicus 251000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6927014 103989456 58001 C05587 ZINC00119675 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064108 Oc1cc2[C@H](CN(CC=C)CCc2c(Br)c1O)c1ccccc1 InChI=1S/C19H20BrNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m1/s1 KKZGFVAZUKHFAC-MRXNPFEDSA-N 50004921 (R)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)6-Br-APB)::CHEMBL34095::R-(+)6-Br-APD3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10452020 103918468 CHEMBL34095 ZINC02530683 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064109 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 8 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064110 COc1cc(CC[NH3+])ccc1O InChI=1S/C9H13NO2/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,11H,4-5,10H2,1H3/p+1 DIVQKHQLANKJQO-UHFFFAOYSA-O 50091035 2-(4-Hydroxy-3-methoxy-phenyl)-ethyl-ammonium(3-methoxytyramine)::3-O-methyldopamine D(2) dopamine receptor Rattus norvegicus 88000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6927014 103989456 58001 C05587 ZINC00119675 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064111 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 49000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064112 C[N@@H+]1C[C@@H](C=C2[C@H]1Cc1c[nH]c3cccc2c13)C(N)=O InChI=1S/C16H17N3O/c1-19-8-10(16(17)20)5-12-11-3-2-4-13-15(11)9(7-18-13)6-14(12)19/h2-5,7,10,14,18H,6,8H2,1H3,(H2,17,20)/p+1/t10-,14-/m1/s1 GENAHGKEFJLNJB-QMTHXVAHSA-O 50091033 9-Carbamoyl-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-7-ium(alpha-ergocriptine)::d-Lysergic acid amide D(2) dopamine receptor Rattus norvegicus 0.62 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332913 103989454 4819 C09160 ZINC56727892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064113 CCCN(CCc1ccccc1)C1CCc2c(O)cccc2C1 InChI=1S/C21H27NO/c1-2-14-22(15-13-17-7-4-3-5-8-17)19-11-12-20-18(16-19)9-6-10-21(20)23/h3-10,19,23H,2,11-16H2,1H3 DEYFWGXTPWNADC-UHFFFAOYSA-N 50010289 (R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(RS)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL109684::N-0434 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1240 103923108 CHEMBL109684 ZINC02169418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064114 C[N@@H+]1C[C@@H](C=C2[C@H]1Cc1c[nH]c3cccc2c13)C(N)=O InChI=1S/C16H17N3O/c1-19-8-10(16(17)20)5-12-11-3-2-4-13-15(11)9(7-18-13)6-14(12)19/h2-5,7,10,14,18H,6,8H2,1H3,(H2,17,20)/p+1/t10-,14-/m1/s1 GENAHGKEFJLNJB-QMTHXVAHSA-O 50091033 9-Carbamoyl-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-7-ium(alpha-ergocriptine)::d-Lysergic acid amide D(2) dopamine receptor Rattus norvegicus 2.8 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332913 103989454 4819 C09160 ZINC56727892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064115 Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 InChI=1S/C16H16ClNO3/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21/h1-4,7,13,18-21H,5-6,8H2 TVURRHSHRRELCG-UHFFFAOYSA-N 60917 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::FENOLDOPAM::FENOLDOPAM MESYLATE::MLS001401388::SMR000469190::cid_49659 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G3C 7CKW,7X2C 3341 252640133 DB00800 C07693 ZINC22116612 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064116 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 600 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064117 CCCN(CCc1ccccc1)C1CCc2c(O)cccc2C1 InChI=1S/C21H27NO/c1-2-14-22(15-13-17-7-4-3-5-8-17)19-11-12-20-18(16-19)9-6-10-21(20)23/h3-10,19,23H,2,11-16H2,1H3 DEYFWGXTPWNADC-UHFFFAOYSA-N 50010289 (R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(RS)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL109684::N-0434 D(2) dopamine receptor Rattus norvegicus 90 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1240 103923108 CHEMBL109684 ZINC02169418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064118 CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18+/m0/s1 BKRGVLQUQGGVSM-KBXCAEBGSA-N 50056445 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea::CHEMBL157138::N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea::lisuride::lisuride, (S) D(2) dopamine receptor Rattus norvegicus 0.40 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search H8G 7WC7,7UM6,6DRX 28864 103952701 51164 CHEMBL157138 DB00589 43 ZINC03831001 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064119 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 1900 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064120 C[N@@H+]1C[C@@H](C=C2[C@H]1Cc1c[nH]c3cccc2c13)C(N)=O InChI=1S/C16H17N3O/c1-19-8-10(16(17)20)5-12-11-3-2-4-13-15(11)9(7-18-13)6-14(12)19/h2-5,7,10,14,18H,6,8H2,1H3,(H2,17,20)/p+1/t10-,14-/m1/s1 GENAHGKEFJLNJB-QMTHXVAHSA-O 50091033 9-Carbamoyl-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-7-ium(alpha-ergocriptine)::d-Lysergic acid amide D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332913 103989454 4819 C09160 ZINC56727892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064121 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064122 CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1 BLYMJBIZMIGWFK-OAHLLOKOSA-N 50054067 (2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium(R(+)7OH-DPAT)::(R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol.HCl::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL301559 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603867 103950725 CHEMBL301559 ZINC03870310 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064123 Oc1cc2[C@H](CN(CC=C)CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m1/s1 HJWHHQIVUHOBQN-MRXNPFEDSA-N 50049048 (R)-3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-3-Allyl-6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::3-Allyl-6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(Cl-APB)::CHEMBL317741::SK&F-82958::SK-82958 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331310 103979426 CHEMBL317741 ZINC03870318 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064124 CCCN1Cc2c(C)cccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 InChI=1S/C21H25NO2/c1-3-9-22-12-17-13(2)5-4-6-15(17)21-16-11-20(24)19(23)10-14(16)7-8-18(21)22/h4-6,10-11,18,21,23-24H,3,7-9,12H2,1-2H3/t18-,21-/m1/s1 IURHNFGBYOFFDB-WIYYLYMNSA-N 50032516 (6aR,12bS)-4-Methyl-6-propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-4-methyl-6-propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(4-MNP-DHX)::CHEMBL104141 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10314127 103941014 CHEMBL104141 ZINC13478192 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064125 [NH3+][C@@H]1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2/p+1/t8-/m1/s1 ASXGAOFCKGHGMF-MRVPVSSYSA-O 50091032 6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl-ammonium(R(+)ADTN)::Aminotetralin-6,7-dihydroxy-(+) D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332855 103989453 ZINC03872369 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064127 Oc1cc2[C@H](CN(CC=C)CCc2c(Br)c1O)c1ccccc1 InChI=1S/C19H20BrNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m1/s1 KKZGFVAZUKHFAC-MRXNPFEDSA-N 50004921 (R)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)6-Br-APB)::CHEMBL34095::R-(+)6-Br-APD3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10452020 103918468 CHEMBL34095 ZINC02530683 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064128 Oc1cc2[C@H](C[NH2+]CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2/p+1/t13-/m1/s1 GHWJEDJMOVUXEC-CYBMUJFWSA-O 50067726 (R)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(6-Cl-PB)::SKF 81297 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332751 103962153 ZINC03783980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064129 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064130 Oc1cc2[C@H](C[NH2+]CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2/p+1/t13-/m1/s1 GHWJEDJMOVUXEC-CYBMUJFWSA-O 50067726 (R)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(6-Cl-PB)::SKF 81297 D(2) dopamine receptor Rattus norvegicus 3000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332751 103962153 ZINC03783980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064131 COc1cc(CC[NH3+])ccc1O InChI=1S/C9H13NO2/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,11H,4-5,10H2,1H3/p+1 DIVQKHQLANKJQO-UHFFFAOYSA-O 50091035 2-(4-Hydroxy-3-methoxy-phenyl)-ethyl-ammonium(3-methoxytyramine)::3-O-methyldopamine D(2) dopamine receptor Rattus norvegicus 94000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6927014 103989456 58001 C05587 ZINC00119675 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064132 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064134 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064136 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 8 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064137 CCCN1Cc2c(C)cccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 InChI=1S/C21H25NO2/c1-3-9-22-12-17-13(2)5-4-6-15(17)21-16-11-20(24)19(23)10-14(16)7-8-18(21)22/h4-6,10-11,18,21,23-24H,3,7-9,12H2,1-2H3/t18-,21-/m1/s1 IURHNFGBYOFFDB-WIYYLYMNSA-N 50032516 (6aR,12bS)-4-Methyl-6-propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-4-methyl-6-propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(4-MNP-DHX)::CHEMBL104141 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10314127 103941014 CHEMBL104141 ZINC13478192 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064140 Oc1cc2CCNCC(c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2 JUDKOGFHZYMDMF-UHFFFAOYSA-N 50004923 (+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514 D(2) dopamine receptor Rattus norvegicus 46000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1242 103918470 CHEMBL505308CHEMBL286080CHEMBL542700 935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064141 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 6700 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064143 C[N@@H+]1C[C@@H](C=C2[C@H]1Cc1c[nH]c3cccc2c13)C(N)=O InChI=1S/C16H17N3O/c1-19-8-10(16(17)20)5-12-11-3-2-4-13-15(11)9(7-18-13)6-14(12)19/h2-5,7,10,14,18H,6,8H2,1H3,(H2,17,20)/p+1/t10-,14-/m1/s1 GENAHGKEFJLNJB-QMTHXVAHSA-O 50091033 9-Carbamoyl-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-7-ium(alpha-ergocriptine)::d-Lysergic acid amide D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332913 103989454 4819 C09160 ZINC56727892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064144 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 6200 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064145 Oc1cc2[C@H](CN(CC=C)CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m1/s1 HJWHHQIVUHOBQN-MRXNPFEDSA-N 50049048 (R)-3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-3-Allyl-6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::3-Allyl-6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(Cl-APB)::CHEMBL317741::SK&F-82958::SK-82958 D(2) dopamine receptor Rattus norvegicus 1600 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331310 103979426 CHEMBL317741 ZINC03870318 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064147 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064148 Oc1cc2[C@H](CN(CC=C)CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m1/s1 HJWHHQIVUHOBQN-MRXNPFEDSA-N 50049048 (R)-3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-3-Allyl-6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::3-Allyl-6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(Cl-APB)::CHEMBL317741::SK&F-82958::SK-82958 D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331310 103979426 CHEMBL317741 ZINC03870318 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064149 Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 InChI=1S/C16H16ClNO3/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21/h1-4,7,13,18-21H,5-6,8H2 TVURRHSHRRELCG-UHFFFAOYSA-N 60917 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::FENOLDOPAM::FENOLDOPAM MESYLATE::MLS001401388::SMR000469190::cid_49659 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G3C 7CKW,7X2C 3341 252640133 DB00800 C07693 ZINC22116612 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064150 Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 InChI=1S/C16H16ClNO3/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21/h1-4,7,13,18-21H,5-6,8H2 TVURRHSHRRELCG-UHFFFAOYSA-N 60917 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::FENOLDOPAM::FENOLDOPAM MESYLATE::MLS001401388::SMR000469190::cid_49659 D(2) dopamine receptor Rattus norvegicus 1900 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G3C 7CKW,7X2C 3341 252640133 DB00800 C07693 ZINC22116612 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064152 CCCN(CCc1ccccc1)C1CCc2c(O)cccc2C1 InChI=1S/C21H27NO/c1-2-14-22(15-13-17-7-4-3-5-8-17)19-11-12-20-18(16-19)9-6-10-21(20)23/h3-10,19,23H,2,11-16H2,1H3 DEYFWGXTPWNADC-UHFFFAOYSA-N 50010289 (R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(RS)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL109684::N-0434 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1240 103923108 CHEMBL109684 ZINC02169418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064153 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 1600 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064154 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 9 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064157 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Rattus norvegicus 2500 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064159 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 520 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064161 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Rattus norvegicus 2300 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064163 Oc1cc2CCNCC(c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2 JUDKOGFHZYMDMF-UHFFFAOYSA-N 50004923 (+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514 D(2) dopamine receptor Rattus norvegicus 39000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1242 103918470 CHEMBL505308CHEMBL286080CHEMBL542700 935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064164 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064166 Oc1cc2CCNCC(c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2 JUDKOGFHZYMDMF-UHFFFAOYSA-N 50004923 (+/-)-SKF-38393::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393)::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393)::CHEMBL286080::CHEMBL505308::CHEMBL542700::RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-38393::SK-38393::SKF 38393::SKF-38393::US9359372, SKF38393::cid_147514 D(2) dopamine receptor Rattus norvegicus 135000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1242 103918470 CHEMBL505308CHEMBL286080CHEMBL542700 935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065288 CN1CCC(CC1)=C1c2ccccc2C=Cc2ccccc12 InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3 JJCFRYNCJDLXIK-UHFFFAOYSA-N 50017721 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine::1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine::4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine::4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine::4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine::5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene::CHEMBL516::CYPROHEPTADINE D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search C7H 5AYF 2913 103928989 4046 CHEMBL516 DB00434 277 C06935 ZINC00968264 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065289 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-21-22(16-30(23(21)15-18)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) KAVXLKNTCZXGHC-UHFFFAOYSA-N 50001772 1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL423009 D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001772&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9889487 103916145 CHEMBL423009 ZINC13731159 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065290 Fc1ccc(cc1)[C@@H]1C[C@@H](N2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H29FN4O/c25-19-7-5-18(6-8-19)22-17-23(21-4-2-1-3-20(21)22)28-14-11-27(12-15-28)13-16-29-10-9-26-24(29)30/h1-8,22-23H,9-17H2,(H,26,30)/t22-,23+/m0/s1 GHAMYXPEZSUOCU-XZOQPEGZSA-N 50020232 1-(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one(Irindalone)::CHEMBL73461::Irindalone D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020232&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65845 103931146 CHEMBL73461 ZINC22463226 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065293 Cc1cccc2c(cn(C3CCN(CCN4CCNC4=O)CC3)c12)-c1ccc(F)cc1 InChI=1S/C25H29FN4O/c1-18-3-2-4-22-23(19-5-7-20(26)8-6-19)17-30(24(18)22)21-9-12-28(13-10-21)15-16-29-14-11-27-25(29)31/h2-8,17,21H,9-16H2,1H3,(H,27,31) BTXNBVXZBBDLMA-UHFFFAOYSA-N 50001814 1-(2-{4-[3-(4-Fluoro-phenyl)-7-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL144901 D(2) dopamine receptor Rattus norvegicus 370 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10047772 103916187 CHEMBL144901 ZINC13731245 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065294 Cc1ccc2n(cc(-c3ccc(F)cc3)c2c1)C1CCN(CCN2CCNC2=O)CC1 InChI=1S/C25H29FN4O/c1-18-2-7-24-22(16-18)23(19-3-5-20(26)6-4-19)17-30(24)21-8-11-28(12-9-21)14-15-29-13-10-27-25(29)31/h2-7,16-17,21H,8-15H2,1H3,(H,27,31) LZSPHUKWGNMGSE-UHFFFAOYSA-N 50001803 1-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL144767 D(2) dopamine receptor Rattus norvegicus 920 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10364835 103916176 CHEMBL144767 ZINC00604451 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065295 Cc1c(C2CCN(CCN3CCNC3=O)CC2)c2ccccc2n1-c1ccc(F)cc1 InChI=1S/C25H29FN4O/c1-18-24(19-10-13-28(14-11-19)16-17-29-15-12-27-25(29)31)22-4-2-3-5-23(22)30(18)21-8-6-20(26)7-9-21/h2-9,19H,10-17H2,1H3,(H,27,31) OOHASZCAJGUYFP-UHFFFAOYSA-N 50001797 1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL423024 D(2) dopamine receptor Rattus norvegicus 380 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10387431 103916170 CHEMBL423024 ZINC13731225 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065299 OCCN1CCN(CC1)[C@@H]1C[C@H](c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2/t19-,21+/m0/s1 JSBWGXQXCRYYTG-PZJWPPBQSA-N 50019966 2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL95636::Tefludazine D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71240 103930889 CHEMBL95636 ZINC22463345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065300 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 1800 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065302 Cc1c(-c2ccc(F)cc2)c2cc(C)ccc2n1C1=CCN(CCN2CCNC2=O)CC1 InChI=1S/C26H29FN4O/c1-18-3-8-24-23(17-18)25(20-4-6-21(27)7-5-20)19(2)31(24)22-9-12-29(13-10-22)15-16-30-14-11-28-26(30)32/h3-9,17H,10-16H2,1-2H3,(H,28,32) REEDEDPSJLIHLC-UHFFFAOYSA-N 50001807 1-(2-{4-[3-(4-Fluoro-phenyl)-2,5-dimethyl-indol-1-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL143617 D(2) dopamine receptor Rattus norvegicus 6300 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10048445 103916180 CHEMBL143617 ZINC27524528 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065303 CN1CCC(CC1)=C1c2ccccc2C(O)c2ccccc12 InChI=1S/C20H21NO/c1-21-12-10-14(11-13-21)19-15-6-2-4-8-17(15)20(22)18-9-5-3-7-16(18)19/h2-9,20,22H,10-13H2,1H3 HLBRHTFSMMEHPK-UHFFFAOYSA-N 50041019 10-(1-Methyl-piperidin-4-ylidene)-9,10-dihydro-anthracen-9-ol::CHEMBL440557::Danitracen D(2) dopamine receptor Rattus norvegicus 1600 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 35758 103972884 CHEMBL440557 ZINC01481770 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065307 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065309 CN1CCN(CC1)[C@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m0/s1 XRYLGRGAWQSVQW-KRWDZBQOSA-N 50007568 1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL303313::OCTOCLOTHEPIN-S D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12765746 103920838 CHEMBL303313 ZINC19368911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065311 Cc1ccc2n(cc(-c3ccc(F)cc3)c2c1)C1=CCN(CCN2CCNC2=O)CC1 InChI=1S/C25H27FN4O/c1-18-2-7-24-22(16-18)23(19-3-5-20(26)6-4-19)17-30(24)21-8-11-28(12-9-21)14-15-29-13-10-27-25(29)31/h2-8,16-17H,9-15H2,1H3,(H,27,31) NCIFROQGTVGVHM-UHFFFAOYSA-N 50001811 1-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL343034 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9931837 103916184 CHEMBL343034 ZINC13731253 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065312 Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-3-6-21-22(17-1-4-19(26)5-2-17)16-30(23(21)15-18)20-7-10-28(11-8-20)13-14-29-12-9-27-24(29)31/h1-6,15-16,20H,7-14H2,(H,27,31) IXWMONQJSSRIPH-UHFFFAOYSA-N 50001806 1-(2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL422130 D(2) dopamine receptor Rattus norvegicus 37 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10094822 103916179 CHEMBL422130 ZINC13731228 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065313 Cc1c(C2=CCN(CCN3CCNC3=O)CC2)c2ccccc2n1-c1ccc(F)cc1 InChI=1S/C25H27FN4O/c1-18-24(19-10-13-28(14-11-19)16-17-29-15-12-27-25(29)31)22-4-2-3-5-23(22)30(18)21-8-6-20(26)7-9-21/h2-10H,11-17H2,1H3,(H,27,31) QNKNONFOUXSKRI-UHFFFAOYSA-N 50001776 1-(2-{4-[1-(4-Fluoro-phenyl)-2-methyl-1H-indol-3-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL422840 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001776&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10409784 103916149 CHEMBL422840 ZINC13731222 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065316 Fc1ccc(cc1)-c1cn(C2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H27FN4O/c25-19-7-5-18(6-8-19)22-17-29(23-4-2-1-3-21(22)23)20-9-12-27(13-10-20)15-16-28-14-11-26-24(28)30/h1-8,17,20H,9-16H2,(H,26,30) TWERGYLJSRWLJS-UHFFFAOYSA-N 50001802 1-(2-{4-[3-(4-Fluoro-phenyl)-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL359031 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10409070 103916175 CHEMBL359031 ZINC13731231 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065317 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065318 Fc1ccc(cc1)[C@@H]1C[C@@H](N2CCN(CCN3CCNC3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C24H28ClFN4O/c25-18-3-6-20-22(15-18)21(17-1-4-19(26)5-2-17)16-23(20)29-12-9-28(10-13-29)11-14-30-8-7-27-24(30)31/h1-6,15,21,23H,7-14,16H2,(H,27,31)/t21-,23+/m0/s1 SUHGCSTVQXPTOC-JTHBVZDNSA-N 50041021 1-(2-{4-[(1R,3S)-5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL366527 D(2) dopamine receptor Rattus norvegicus 360 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041021&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44386356 103972886 CHEMBL366527 ZINC22940752 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065319 Fc1ccc(cc1)-n1cc(C2=CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H25FN4O/c25-19-5-7-20(8-6-19)29-17-22(21-3-1-2-4-23(21)29)18-9-12-27(13-10-18)15-16-28-14-11-26-24(28)30/h1-9,17H,10-16H2,(H,26,30) FPFNLDJLMDWQNP-UHFFFAOYSA-N 50041022 1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-3,6-dihydro-2H-pyridin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL176643 D(2) dopamine receptor Rattus norvegicus 5.1 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041022&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15006454 103972887 CHEMBL176643 ZINC13600919 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065320 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H27FN4O/c25-19-5-7-20(8-6-19)29-17-22(21-3-1-2-4-23(21)29)18-9-12-27(13-10-18)15-16-28-14-11-26-24(28)30/h1-8,17-18H,9-16H2,(H,26,30) QPOLRENOYJQNEP-UHFFFAOYSA-N 50001778 (Lu 23-086)1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL12780 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742071 103916151 CHEMBL12780 ZINC13452450 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065296 Cc1c(-c2ccc(F)cc2)c2cc(C)ccc2n1C1CCN(CCN2CCNC2=O)CC1 InChI=1S/C26H31FN4O/c1-18-3-8-24-23(17-18)25(20-4-6-21(27)7-5-20)19(2)31(24)22-9-12-29(13-10-22)15-16-30-14-11-28-26(30)32/h3-8,17,22H,9-16H2,1-2H3,(H,28,32) OUEICZGYFSHCOY-UHFFFAOYSA-N 50001800 1-(2-{4-[3-(4-Fluoro-phenyl)-2,5-dimethyl-indol-1-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL343444 D(2) dopamine receptor Rattus norvegicus 6900 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9845791 103916173 CHEMBL343444 ZINC00604455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50065297 CN1CCC(CC1)=C1c2ccccc2C=Cc2ccc(Br)cc12 InChI=1S/C21H20BrN/c1-23-12-10-17(11-13-23)21-19-5-3-2-4-15(19)6-7-16-8-9-18(22)14-20(16)21/h2-9,14H,10-13H2,1H3 NSSCINRMNOIVGT-UHFFFAOYSA-N 50041020 4-(3-Bromo-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-piperidine::CHEMBL436095 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm00033a013 10.7270/Q2GF0SKK 8151622 Andersen, K; Liljefors, T; Gundertofte, K; Perregaard, J; Bogeso, KP H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23343659 103972885 CHEMBL436095 ZINC13600922 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063430 Fc1ccc(CN2CCC[C@H]2CNC(=O)c2cc(I)cc3CCOc23)cc1 InChI=1S/C21H22FIN2O2/c22-16-5-3-14(4-6-16)13-25-8-1-2-18(25)12-24-21(26)19-11-17(23)10-15-7-9-27-20(15)19/h3-6,10-11,18H,1-2,7-9,12-13H2,(H,24,26)/t18-/m0/s1 YLNWTPBWQPADOJ-SFHVURJKSA-N 50040077 5-Iodo-2,3-dihydro-benzofuran-7-carboxylic acid [1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-amide (IBF)::CHEMBL431384 D(2) dopamine receptor Rattus norvegicus 0.106000 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040077&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312781 103972140 CHEMBL431384 ZINC26381493 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063431 CCN1CCC[C@@H]1CNC(=O)c1cccc(OC)c1OCCF InChI=1S/C17H25FN2O3/c1-3-20-10-5-6-13(20)12-19-17(21)14-7-4-8-15(22-2)16(14)23-11-9-18/h4,7-8,13H,3,5-6,9-12H2,1-2H3,(H,19,21)/t13-/m1/s1 HIMNZPDOJYAPJQ-CYBMUJFWSA-N 50040078 CHEMBL305844::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-(2-fluoro-ethoxy)-3-methoxy-benzamide (FEOB) D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040078&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44313023 103972141 CHEMBL305844 ZINC26383148 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063432 CCN1CCC[C@H]1CNC(=O)c1cc(CCCF)cc(OC)c1OC InChI=1S/C19H29FN2O3/c1-4-22-10-6-8-15(22)13-21-19(23)16-11-14(7-5-9-20)12-17(24-2)18(16)25-3/h11-12,15H,4-10,13H2,1-3H3,(H,21,23)/t15-/m0/s1 CRDCKDWZBHLFAS-HNNXBMFYSA-N 50008785 CHEMBL42953::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(3-fluoro-propyl)-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(3-fluoro-propyl)-2,3-dimethoxy-benzamide (FP-epidepride) D(2) dopamine receptor Rattus norvegicus 0.020000 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10043596 103921914 CHEMBL42953 ZINC05650383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063433 CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)ccc1OC InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 CANPFCFJURGKAX-JTQLQIEISA-N 50012961 (-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::CHEMBL267723::N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide (IBZM)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide( (S)-(-)IBZM) D(2) dopamine receptor Rattus norvegicus 0.430000 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 107995 103925209 CHEMBL267723 ZINC03786360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063434 CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)cc(OC)c1OC InChI=1S/C16H23IN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 BKJGKGPGPACEQW-JTQLQIEISA-N 50040079 CHEMBL308524::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-5,6-dimethoxy-benzamide (ioxipride)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-5,6-dimethoxy-benzamide( NCQ 298) D(2) dopamine receptor Rattus norvegicus 0.019000 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040079&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14601425 103972142 CHEMBL308524 ZINC03785266 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063435 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063436 COc1cc(Br)cc(C(=O)NC[C@@H]2CCCN2Cc2ccc(F)cc2)c1OC InChI=1S/C21H24BrFN2O3/c1-27-19-11-15(22)10-18(20(19)28-2)21(26)24-12-17-4-3-9-25(17)13-14-5-7-16(23)8-6-14/h5-8,10-11,17H,3-4,9,12-13H2,1-2H3,(H,24,26)/t17-/m0/s1 OHMIBGFTDCPQGJ-KRWDZBQOSA-N 50007521 5-Bromo-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2,3-dimethoxy-benzamide (NCQ115)::CHEMBL1204286::CHEMBL73683 D(2) dopamine receptor Rattus norvegicus 0.147000 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007521&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14880710 103920796 CHEMBL1204286CHEMBL73683 ZINC13820623 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063437 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor Rattus norvegicus 0.025000 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063438 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.090000 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063439 CCN1CCC[C@H]1CNC(=O)c1cc(I)ccc1OC InChI=1S/C15H21IN2O2/c1-3-18-8-4-5-12(18)10-17-15(19)13-9-11(16)6-7-14(13)20-2/h6-7,9,12H,3-5,8,10H2,1-2H3,(H,17,19)/t12-/m0/s1 JHMTYLJMPBFCTD-LBPRGKRZSA-N 50012967 CHEMBL49897::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide (iodopride)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide(iodopride) D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977544 103925215 CHEMBL49897 ZINC06385022 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063440 CCN1CCC[C@H]1CNC(=O)c1c(I)c(ccc1OC)S(N)(=O)=O InChI=1S/C15H22IN3O4S/c1-3-19-8-4-5-10(19)9-18-15(20)13-11(23-2)6-7-12(14(13)16)24(17,21)22/h6-7,10H,3-5,8-9H2,1-2H3,(H,18,20)(H2,17,21,22)/t10-/m0/s1 HCKMONAVUWHQOT-JTQLQIEISA-N 50040082 CHEMBL307023::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-iodo-6-methoxy-3-sulfamoyl-benzamide (iodosulpride)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoyl-benzamide(iodosulpiride) D(2) dopamine receptor Rattus norvegicus 1.5 ChEMBL 10.1021/jm00054a005 10.7270/Q2TT4Q10 8093734 Chumpradit, S; Kung, MP; Billings, J; Mach, R; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040082&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312731 103972143 CHEMBL307023 ZINC26376795 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063488 C1CN(C[C@@H]2CCc3ccccc3[C@H]12)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C23H31N/c1-2-4-21-19(3-1)5-6-20-15-24(8-7-22(20)21)23-12-16-9-17(13-23)11-18(10-16)14-23/h1-4,16-18,20,22H,5-15H2/t16-,17+,18-,20-,22+,23?/m0/s1 FMFPCXNMOGPMDI-GCJCMNQMSA-N 50421904 CHEMBL553561 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421904&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44304421 164150779 CHEMBL553561 ZINC26166299 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062479 C(CCc1ccco1)CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C21H24N2O/c1-2-9-18-17(8-1)21-19(22-18)14-15-10-11-20(21)23(15)12-4-3-6-16-7-5-13-24-16/h1-2,5,7-9,13,15,20,22H,3-4,6,10-12,14H2 BBNMJCHVYDPLHH-UHFFFAOYSA-N 50046459 (+)-1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(2-furyl)butane::(+/-)-1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(2-furyl)butane::(-)-1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(2-furyl)butane::1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(2-furyl)butane::CHEMBL117898 D(2) dopamine receptor Rattus norvegicus 1270 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149404 103977244 CHEMBL117898 ZINC13861335 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063621 CCCN1[C@H](C)CC2[C@H]1CCc1cccc(OC)c21 InChI=1S/C17H25NO/c1-4-10-18-12(2)11-14-15(18)9-8-13-6-5-7-16(19-3)17(13)14/h5-7,12,14-15H,4,8-11H2,1-3H3/t12-,14?,15-/m1/s1 FWQJZNALGBTYNB-SULGFLJSSA-N 50040158 9-Methoxy-2-methyl-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10561 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266668 103972218 CHEMBL10561 ZINC26010228 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063636 COc1cccc2CC[C@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13?,14-/m0/s1 VRRJFCMGNMFNOE-KZUDCZAMSA-N 50040166 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL418705 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266613 103972226 CHEMBL418705 ZINC13826496 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063638 CCCN1CC[C@@H]2[C@H]1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3/t13?,14-/m0/s1 HPUKPOAWHHZLIX-KZUDCZAMSA-N 50040167 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL267812 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040167&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10332127 103972227 CHEMBL267812 ZINC13826500 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063644 COc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13?,15-/m1/s1 ZRAGXRIXRXDXCR-AWKYBWMHSA-N 50040170 (Recemic)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10570 D(2) dopamine receptor Rattus norvegicus 42.0 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266689 103972230 CHEMBL10570 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063645 CCCN1[C@@H](C)CC2[C@H]1CCc1cccc(OC)c21 InChI=1S/C17H25NO/c1-4-10-18-12(2)11-14-15(18)9-8-13-6-5-7-16(19-3)17(13)14/h5-7,12,14-15H,4,8-11H2,1-3H3/t12-,14?,15+/m0/s1 FWQJZNALGBTYNB-XSDATEAUSA-N 50040171 9-Methoxy-2-methyl-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL273614 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266676 103972231 CHEMBL273614 ZINC26009901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063650 CCCN1CC[C@H]2[C@@H]1CCc1cccc(O)c21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h3-5,12-13,17H,2,6-10H2,1H3/t12?,13-/m1/s1 UVOXCNCVSFLEPX-ZGTCLIOFSA-N 50040175 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL9979 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040175&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10059787 103972235 CHEMBL9979 ZINC26004503 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063662 COc1cccc2CC[C@@H]3C(CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13?,14-/m1/s1 VRRJFCMGNMFNOE-ARLHGKGLSA-N 50040177 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10270 D(2) dopamine receptor Rattus norvegicus 5.3 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266664 103972237 CHEMBL10270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063668 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063669 Oc1cccc2C3CCN(CC=C)[C@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12?,14-/m0/s1 MHHLELSXRBTNRD-PYMCNQPYSA-N 50040179 (Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL275543 D(2) dopamine receptor Rattus norvegicus 259 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266663 103972239 CHEMBL275543 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063672 CCCN1CC[C@@H]2[C@H]1CCc1cccc(O)c21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h3-5,12-13,17H,2,6-10H2,1H3/t12?,13-/m0/s1 UVOXCNCVSFLEPX-ABLWVSNPSA-N 50040161 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL276185 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040161&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014136 103972221 CHEMBL276185 ZINC13826513 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063676 CCCN1CC[C@H]2[C@@H]1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3/t13?,14-/m1/s1 HPUKPOAWHHZLIX-ARLHGKGLSA-N 50040176 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10714 D(2) dopamine receptor Rattus norvegicus 67 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040176&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037522 103972236 CHEMBL10714 ZINC26009982 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063680 CCCN1CCC2C1CCc1cccc(O)c21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h3-5,12-13,17H,2,6-10H2,1H3 UVOXCNCVSFLEPX-UHFFFAOYSA-N 50040173 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL9980 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14944886 103972233 CHEMBL9980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063683 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063695 Oc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12?,14-/m1/s1 MHHLELSXRBTNRD-TYZXPVIJSA-N 50040165 3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL10408 D(2) dopamine receptor Rattus norvegicus 49 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266677 103972225 CHEMBL10408 ZINC13826519 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063712 CCCN1CCC2C1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3 HPUKPOAWHHZLIX-UHFFFAOYSA-N 50040181 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10677 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18988846 103972241 CHEMBL10677 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063746 CCCN(C)[C@@H]1Cc2ccc(O)cc2[C@H]1c1ccccc1 InChI=1S/C19H23NO/c1-3-11-20(2)18-12-15-9-10-16(21)13-17(15)19(18)14-7-5-4-6-8-14/h4-10,13,18-19,21H,3,11-12H2,1-2H3/t18-,19-/m1/s1 JSEXLEGBBZMMOQ-RTBURBONSA-N 50054088 (2R,3R)-2-(Methyl-propyl-amino)-3-phenyl-indan-5-ol::CHEMBL433652 D(2) dopamine receptor Rattus norvegicus 0.34 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054088&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10802788 103950746 CHEMBL433652 ZINC27431219 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063749 CCCN(CCC)[C@H]1CCc2c(F)ccc(O)c2C1 InChI=1S/C16H24FNO/c1-3-9-18(10-4-2)12-5-6-13-14(11-12)16(19)8-7-15(13)17/h7-8,12,19H,3-6,9-11H2,1-2H3/t12-/m0/s1 FNKBVTBXFLSTPB-LBPRGKRZSA-N 50013019 (S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydronaphthalen-1-ol::(S)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-UH-301::7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol::7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol ((S)-UH301)::CHEMBL22778::UH-301 D(2) dopamine receptor Rattus norvegicus 614 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122187 103925253 CHEMBL22778 61 C11698 ZINC03874895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062732 COc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13-,14-/m1/s1 VRRJFCMGNMFNOE-ZIAGYGMSSA-N 50034330 (3aR,9bS) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-3-allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aS,9bR) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL26118 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105844 103942531 CHEMBL26118 ZINC03790769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062733 CCCN1CC[C@@H]2[C@H]1CCc1c(OC)cccc21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15+/m0/s1 VUKJBNUKLLGULS-DZGCQCFKSA-N 50034351 (3aR,9bS)-6-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25177 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14944883 103942552 CHEMBL25177 ZINC00013944 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062734 COc1cccc2[C@H]3CCN(CC4CC4)[C@@H]3CCc12 InChI=1S/C17H23NO/c1-19-17-4-2-3-13-14-9-10-18(11-12-5-6-12)16(14)8-7-15(13)17/h2-4,12,14,16H,5-11H2,1H3/t14-,16-/m1/s1 DSBCJIBAHMOGIR-GDBMZVCRSA-N 50034336 (3aR,9bR)-3-Cyclopropylmethyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24532 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377779 103942537 CHEMBL24532 ZINC26010242 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062735 CCCN1CC[C@H]2[C@H]1CCc1c(OC)cccc21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1 VUKJBNUKLLGULS-UKRRQHHQSA-N 50034326 (3aR,9bR)-6-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280137 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992098 103942527 CHEMBL280137 ZINC28757900 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062736 C=CCN1CC[C@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H19N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h2-6,14-15H,1,7-11H2/t14-,15-/m1/s1 KJAVUVIRTPBAPJ-HUUCEWRRSA-N 50034335 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL286006 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034335&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353170 103942536 CHEMBL286006 ZINC28757606 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062740 CCCN1CC[C@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H21N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h3-6,14-15H,2,7-11H2,1H3/t14-,15-/m1/s1 ANSBSVSYIULXCZ-HUUCEWRRSA-N 50034316 (3aR,9bR)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24496 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034316&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10443274 103942517 CHEMBL24496 ZINC28756694 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062743 COc1cccc2[C@@H]3CCN(CC4CC4)[C@@H]3CCc12 InChI=1S/C17H23NO/c1-19-17-4-2-3-13-14-9-10-18(11-12-5-6-12)16(14)8-7-15(13)17/h2-4,12,14,16H,5-11H2,1H3/t14-,16+/m0/s1 DSBCJIBAHMOGIR-GOEBONIOSA-N 50034315 (3aR,9bS)-3-Cyclopropylmethyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25691 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034315&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9992630 103942516 CHEMBL25691 ZINC13826506 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062737 Oc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1 MHHLELSXRBTNRD-TZMCWYRMSA-N 50034356 (3aR,9bR)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL25483 D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466368 103942557 CHEMBL25483 ZINC13826519 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062744 COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m0/s1 ZRAGXRIXRXDXCR-DZGCQCFKSA-N 50034341 (3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280955 D(2) dopamine receptor Rattus norvegicus 25.0 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466962 103942542 CHEMBL280955 ZINC00004906 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062745 COc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13-,14-/m1/s1 VRRJFCMGNMFNOE-ZIAGYGMSSA-N 50034330 (3aR,9bS) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-3-allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aS,9bR) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL26118 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105844 103942531 CHEMBL26118 ZINC03790769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062757 COc1cccc2[C@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1 ZRAGXRIXRXDXCR-UKRRQHHQSA-N 50034364 (3aR,9bR)-3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL24222 D(2) dopamine receptor Rattus norvegicus 99 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037436 103942565 CHEMBL24222 ZINC13826504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062759 CCCN1CC[C@@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14+/m0/s1 SHOJVFLWKSRVPH-GXTWGEPZSA-N 50034363 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL26560 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034363&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466454 103942564 CHEMBL26560 ZINC13826523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062760 Oc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h2-5,12-13,17H,1,6-10H2/t12-,13-/m1/s1 NLAWPJROLJRPAW-CHWSQXEVSA-N 50034360 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::(Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL287134 D(2) dopamine receptor Rattus norvegicus 153 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034360&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14944884 103942561 CHEMBL287134 ZINC13826509 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062763 CCCN1CC[C@H]2[C@H]1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1 SHOJVFLWKSRVPH-TZMCWYRMSA-N 50034349 (3aR,9bR)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL24588 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353846 103942550 CHEMBL24588 ZINC28756688 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062765 C=CCN1CC[C@@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H19N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h2-6,14-15H,1,7-11H2/t14-,15+/m0/s1 KJAVUVIRTPBAPJ-LSDHHAIUSA-N 50034337 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25418 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10059274 103942538 CHEMBL25418 ZINC01493037 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062767 Oc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12-,14+/m0/s1 MHHLELSXRBTNRD-GXTWGEPZSA-N 50034355 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::(3aR,9bS)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL285873 D(2) dopamine receptor Rattus norvegicus 198 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014056 103942556 CHEMBL285873 ZINC13826517 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062768 CCCN1CC[C@@H]2[C@H]1CCc1ccccc21 InChI=1S/C15H21N/c1-2-10-16-11-9-14-13-6-4-3-5-12(13)7-8-15(14)16/h3-6,14-15H,2,7-11H2,1H3/t14-,15+/m0/s1 ANSBSVSYIULXCZ-LSDHHAIUSA-N 50034358 (3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL25690 D(2) dopamine receptor Rattus norvegicus 548 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034358&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10420841 103942559 CHEMBL25690 ZINC13826507 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062770 COc1cccc2CC[C@@H]3[C@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13-,14+/m0/s1 VRRJFCMGNMFNOE-UONOGXRCSA-N 50034339 (3aR,9bR)-3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic)3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL286205 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00060a014 10.7270/Q29S1Q3R 8097537 Lin, CH; Haadsma-Svensson, SR; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10354437 103942540 CHEMBL286205 ZINC13826494 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062778 CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1 DYVLYWKEJHHXOH-TZMCWYRMSA-N 50034352 (3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(3aS,9aR)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL11066 D(2) dopamine receptor Rattus norvegicus 17.0 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105311 103942553 CHEMBL11066 ZINC13826575 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062780 Oc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12 InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1 GNOHLPXINNYCLR-TZMCWYRMSA-N 50034346 (3aS,9aR) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(3aS,9aR)-1-allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL11363 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014057 103942547 CHEMBL11363 ZINC13826580 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062787 CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@H]12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14+/m1/s1 DYVLYWKEJHHXOH-OCCSQVGLSA-N 50034319 (3aS,9aS)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL275689 D(2) dopamine receptor Rattus norvegicus 296 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11776081 103942520 CHEMBL275689 ZINC13826553 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062793 CCCN1CC[C@@H]2Cc3c(C[C@@H]12)cccc3OC InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1 HDCVYYTWHHFQGS-UKRRQHHQSA-N 50034324 (3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::(3aS,9aR)-5-methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11388 D(2) dopamine receptor Rattus norvegicus 877 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377224 103942525 CHEMBL11388 ZINC13826563 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50062794 COc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12 InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1 ASEDQXVCNPLEIO-UKRRQHHQSA-N 50034350 (3aS,9aR) 1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::(3aS,9aR)-1-allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11170 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037437 103942551 CHEMBL11170 ZINC13826569 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063932 CN1CCN(CC1)C1=Nc2ccccc2Nc2ncccc12 InChI=1S/C17H19N5/c1-21-9-11-22(12-10-21)17-13-5-4-8-18-16(13)19-14-6-2-3-7-15(14)20-17/h2-8H,9-12H2,1H3,(H,18,19) BDBJMQOWEILZJV-UHFFFAOYSA-N 50017538 5-(4-Methyl-piperazin-1-yl)-11H-benzo[b]pyrido[2,3-e][1,4]diazepine::CHEMBL67355 D(2) dopamine receptor Rattus norvegicus 1966 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017538&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654860 103928806 CHEMBL67355 ZINC26255544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063933 CN1CCN(CC1)C1=Nc2cccnc2Nc2cc(Cl)ccc12 InChI=1S/C17H18ClN5/c1-22-7-9-23(10-8-22)17-13-5-4-12(18)11-15(13)20-16-14(21-17)3-2-6-19-16/h2-6,11H,7-10H2,1H3,(H,19,20) JAKNPEMEUIBACX-UHFFFAOYSA-N 50040238 9-Chloro-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL304493 D(2) dopamine receptor Rattus norvegicus 1020 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040238&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654855 103972298 CHEMBL304493 ZINC13832137 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063940 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 45.0 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063941 CN1CCN(CC1)C1=Nc2ccccc2N(C=O)c2ccncc12 InChI=1S/C18H19N5O/c1-21-8-10-22(11-9-21)18-14-12-19-7-6-16(14)23(13-24)17-5-3-2-4-15(17)20-18/h2-7,12-13H,8-11H2,1H3 DKDZSMWJHAFAFM-UHFFFAOYSA-N 50040242 11-(4-Methyl-piperazin-1-yl)-benzo[b]pyrido[4,3-e][1,4]diazepine-5-carbaldehyde::CHEMBL65768 D(2) dopamine receptor Rattus norvegicus 23900 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040242 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040242&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654863 103972302 CHEMBL65768 ZINC13832145 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063942 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Sc2ccccc12 InChI=1S/C18H18ClN3S/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-16(14)23-17-7-6-13(19)12-15(17)20-18/h2-7,12H,8-11H2,1H3 KPQVFXHERXUYEX-UHFFFAOYSA-N 50040243 8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(isoclothiapine)::8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::8-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL67284 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040243&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9928073 103972303 CHEMBL67284 ZINC13734596 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063944 CN1CCN(CC1)C1=Nc2ccccc2N(C=O)c2ncccc12 InChI=1S/C18H19N5O/c1-21-9-11-22(12-10-21)18-14-5-4-8-19-17(14)23(13-24)16-7-3-2-6-15(16)20-18/h2-8,13H,9-12H2,1H3 IAWYTCDIHYGEQM-UHFFFAOYSA-N 50040240 5-(4-Methyl-piperazin-1-yl)-benzo[b]pyrido[2,3-e][1,4]diazepine-11-carbaldehyde::CHEMBL292738 D(2) dopamine receptor Rattus norvegicus 100000 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654861 103972300 CHEMBL292738 ZINC13832142 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063950 CN1CCN(CC1)C1=Nc2cc(C)cnc2Nc2ccccc12 InChI=1S/C18H21N5/c1-13-11-16-17(19-12-13)20-15-6-4-3-5-14(15)18(21-16)23-9-7-22(2)8-10-23/h3-6,11-12H,7-10H2,1-2H3,(H,19,20) XLWWTPXFRQGJOE-UHFFFAOYSA-N 50040246 3-Methyl-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL63590 D(2) dopamine receptor Rattus norvegicus 297 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040246&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654857 103972306 CHEMBL63590 ZINC13832139 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063954 CN1CCN(CC1)C1=Nc2cccnc2Nc2ccc(F)cc12 InChI=1S/C17H18FN5/c1-22-7-9-23(10-8-22)17-13-11-12(18)4-5-14(13)20-16-15(21-17)3-2-6-19-16/h2-6,11H,7-10H2,1H3,(H,19,20) TVZGDHUGBYQWPQ-UHFFFAOYSA-N 50040248 8-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL63347 D(2) dopamine receptor Rattus norvegicus 1550 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040248&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654856 103972308 CHEMBL63347 ZINC13832138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063965 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccncc12 InChI=1S/C17H19N5/c1-21-8-10-22(11-9-21)17-13-12-18-7-6-14(13)19-15-4-2-3-5-16(15)20-17/h2-7,12,19H,8-11H2,1H3 YIWJZRDFRBCBID-UHFFFAOYSA-N 50040244 11-(4-Methyl-piperazin-1-yl)-5H-benzo[b]pyrido[4,3-e][1,4]diazepine::CHEMBL67298 D(2) dopamine receptor Rattus norvegicus 442 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040244&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654862 103972304 CHEMBL67298 ZINC13832144 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063979 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063983 CN1CCN(CC1)C1=Nc2cccnc2N(C)c2ccccc12 InChI=1S/C18H21N5/c1-21-10-12-23(13-11-21)17-14-6-3-4-8-16(14)22(2)18-15(20-17)7-5-9-19-18/h3-9H,10-13H2,1-2H3 WUASVKNSQAYQRW-UHFFFAOYSA-N 50040236 11-Methyl-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL63390 D(2) dopamine receptor Rattus norvegicus 27100 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040236&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654859 103972296 CHEMBL63390 ZINC13832141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063957 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.880000 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063987 CN1CCN(CC1)C1=Nc2cc(F)ccc2Cc2ccccc12 InChI=1S/C19H20FN3/c1-22-8-10-23(11-9-22)19-17-5-3-2-4-14(17)12-15-6-7-16(20)13-18(15)21-19/h2-7,13H,8-12H2,1H3 OBWGMKKHCLHVIE-UHFFFAOYSA-N 50040241 3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine(fluperlapine)::CHEMBL63756::Fluperlapine D(2) dopamine receptor Rattus norvegicus 133 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 49381 103972301 CHEMBL63756 279 C10967 ZINC26247473 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063988 CN1CCN(CC1)C1=Nc2cccnc2N(C=O)c2ccccc12 InChI=1S/C18H19N5O/c1-21-9-11-22(12-10-21)17-14-5-2-3-7-16(14)23(13-24)18-15(20-17)6-4-8-19-18/h2-8,13H,9-12H2,1H3 LCBGLYREBZKLKZ-UHFFFAOYSA-N 50040247 6-(4-Methyl-piperazin-1-yl)-benzo[e]pyrido[3,2-b][1,4]diazepine-11-carbaldehyde::CHEMBL303435 D(2) dopamine receptor Rattus norvegicus 100000 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654858 103972307 CHEMBL303435 ZINC13832140 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063989 CN1CCN(CC1)C1=Nc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClN3S/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 KAAZGXDPUNNEFN-UHFFFAOYSA-N 50040237 2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(clothiapine)::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL304902::Clothiapine D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040237&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16351 103972297 CHEMBL304902 ZINC26185346 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063993 CN1CCN(CC1)C1=Nc2cccnc2Nc2ccccc12 InChI=1S/C17H19N5/c1-21-9-11-22(12-10-21)17-13-5-2-3-6-14(13)19-16-15(20-17)7-4-8-18-16/h2-8H,9-12H2,1H3,(H,18,19) NKJVNGZDNDSXJO-UHFFFAOYSA-N 50040249 6-(4-Methyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL303173 D(2) dopamine receptor Rattus norvegicus 3652 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654854 103972309 CHEMBL303173 ZINC13832136 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063997 CN1CCN(CC1)C1=Nc2cccnc2Nc2ccc(C)cc12 InChI=1S/C18H21N5/c1-13-5-6-15-14(12-13)18(23-10-8-22(2)9-11-23)21-16-4-3-7-19-17(16)20-15/h3-7,12H,8-11H2,1-2H3,(H,19,20) MMCMKWDIEUZMQB-UHFFFAOYSA-N 50040245 8-Methyl-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL63329 D(2) dopamine receptor Rattus norvegicus 530.0 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040245&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3802 103972305 CHEMBL63329 ZINC53151333 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50063998 CN1CCN(CC1)C1=Nc2cccnc2Nc2ccc(Cl)cc12 InChI=1S/C17H18ClN5/c1-22-7-9-23(10-8-22)17-13-11-12(18)4-5-14(13)20-16-15(21-17)3-2-6-19-16/h2-6,11H,7-10H2,1H3,(H,19,20) QTPHXTPUQBAPOK-UHFFFAOYSA-N 50040250 8-Chloro-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL63576 D(2) dopamine receptor Rattus norvegicus 118 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9927411 103972310 CHEMBL63576 ZINC13492084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064008 CN1CCN(CC1)C1=Nc2cnccc2Nc2ccccc12 InChI=1S/C17H19N5/c1-21-8-10-22(11-9-21)17-13-4-2-3-5-14(13)19-15-6-7-18-12-16(15)20-17/h2-7,12,19H,8-11H2,1H3 OYSWCNPIGMZDAT-UHFFFAOYSA-N 50040239 10-(4-Methyl-piperazin-1-yl)-5H-2,5,11-triaza-dibenzo[a,d]cycloheptene::CHEMBL66730 D(2) dopamine receptor Rattus norvegicus 3970.0 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040239&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44307246 103972299 CHEMBL66730 ZINC13832143 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50064009 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1021/jm00067a009 10.7270/Q22B8X37 8101877 Liegeois, JF; Bruhwyler, J; Damas, J; Nguyen, TP; Chleide, EM; Mercier, MG; Rogister, FA; Delarge, JE University of Liège http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50066873 CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C InChI=1S/C18H29NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-9,14,17H,5-6,10-13H2,1-4H3/t14-,17+/m0/s1 BTOJYCTUJJHANF-WMLDXEAASA-N 50041961 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL278751::UH-232 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604756 103973640 CHEMBL278751 ZINC03995702 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50067983 Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 FELGMEQIXOGIFQ-UHFFFAOYSA-N 85330 CAS_68647::NSC_68647::ONDANSETRON::Ondansetron hydrochloride D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00075a026 10.7270/Q2NS0SZH 8246239 van Wijngaarden, I; Hamminga, D; van Hes, R; Standaar, PJ; Tipker, J; Tulp, MT; Mol, F; Olivier, B; de Jonge, A Solvay Duphar B.V. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search S87 6W1M 4595 136351430 DB00904 C07325 ZINC00075126 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50066910 CCCN1CCC[C@H](C1)c1cccc(OS(=O)(=O)C(F)(F)F)c1 InChI=1S/C15H20F3NO3S/c1-2-8-19-9-4-6-13(11-19)12-5-3-7-14(10-12)22-23(20,21)15(16,17)18/h3,5,7,10,13H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 VUEGBGWRCATKQZ-CYBMUJFWSA-N 50039760 (-)-Trifluoro-methanesulfonic acid 3-(1-propyl-piperidin-3-yl)-phenyl ester::CHEMBL90359::Trifluoro-methanesulfonic acid 3-((S)-1-propyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 135 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039760&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654433 103946955 CHEMBL90359 ZINC36187784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070458 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 222 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070462 COc1ccc2C(CCCN3CCN(CC3)c3ccccc3OC)=CCCc2c1 InChI=1S/C25H32N2O2/c1-28-22-12-13-23-20(7-5-8-21(23)19-22)9-6-14-26-15-17-27(18-16-26)24-10-3-4-11-25(24)29-2/h3-4,7,10-13,19H,5-6,8-9,14-18H2,1-2H3 QSSXSMKCIZLOKB-UHFFFAOYSA-N 50043882 1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL269612 D(2) dopamine receptor Rattus norvegicus 90.6 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043882&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14978223 103975256 CHEMBL269612 ZINC25986342 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070463 CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1 ZZJYIKPMDIWRSN-HWBMXIPRSA-N 50008735 (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(+)-butaclamol::(+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::(S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::BUTACLAMOL::BUTACLAMOL, (-)::BUTACLAMOL,(+)::BUTACLAMOL,d-::CHEMBL8514::d-Butaclamol D(2) dopamine receptor Rattus norvegicus 0.5 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37459 103921865 CHEMBL8514 62 ZINC02008410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070464 COc1ccccc1N1CCN(CCCC2=CCCc3ccccc23)CC1 InChI=1S/C24H30N2O/c1-27-24-14-5-4-13-23(24)26-18-16-25(17-19-26)15-7-11-21-10-6-9-20-8-2-3-12-22(20)21/h2-5,8,10,12-14H,6-7,9,11,15-19H2,1H3 PIZXFQUYIGDMKJ-UHFFFAOYSA-N 50043884 1-[3-(3,4-Dihydro-naphthalen-1-yl)-propyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL8644 D(2) dopamine receptor Rattus norvegicus 14.7 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10316605 103975258 CHEMBL8644 ZINC13733285 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070469 COc1cccc2CCC=C(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)c12 InChI=1S/C25H29F3N2O/c1-31-23-12-3-8-19-6-2-7-20(24(19)23)9-5-13-29-14-16-30(17-15-29)22-11-4-10-21(18-22)25(26,27)28/h3-4,7-8,10-12,18H,2,5-6,9,13-17H2,1H3 BKHFZQKDLQQYGU-UHFFFAOYSA-N 50043888 1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL266534 D(2) dopamine receptor Rattus norvegicus 644 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14978232 103975262 CHEMBL266534 ZINC25985548 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070472 COc1ccc2C(CCCN3CCNCC3)=CCCc2c1 InChI=1S/C18H26N2O/c1-21-17-7-8-18-15(4-2-5-16(18)14-17)6-3-11-20-12-9-19-10-13-20/h4,7-8,14,19H,2-3,5-6,9-13H2,1H3 OQFOIKSARZMXEY-UHFFFAOYSA-N 50043890 1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL8589 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44265481 103975264 CHEMBL8589 ZINC25986254 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070473 COc1ccc2C(CCCN3CCN(CC3)c3cccc(Cl)c3)=CCCc2c1 InChI=1S/C24H29ClN2O/c1-28-23-10-11-24-19(5-2-6-20(24)17-23)7-4-12-26-13-15-27(16-14-26)22-9-3-8-21(25)18-22/h3,5,8-11,17-18H,2,4,6-7,12-16H2,1H3 VWSKELFLZFKMMK-UHFFFAOYSA-N 50043885 1-(3-Chloro-phenyl)-4-[3-(6-methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL8524 D(2) dopamine receptor Rattus norvegicus 768 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14978225 103975259 CHEMBL8524 ZINC25987471 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070475 COc1cccc2CCC=C(CCCN3CCN(CC3)c3ccccn3)c12 InChI=1S/C23H29N3O/c1-27-21-11-5-9-19-7-4-8-20(23(19)21)10-6-14-25-15-17-26(18-16-25)22-12-2-3-13-24-22/h2-3,5,8-9,11-13H,4,6-7,10,14-18H2,1H3 LFPMDBSDZKZDIJ-UHFFFAOYSA-N 50043891 1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL8617 D(2) dopamine receptor Rattus norvegicus 119 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043891&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14978229 103975265 CHEMBL8617 ZINC25986547 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070478 COc1ccc2C(CCCN3CCN(CC3)c3ccccc3)=CCCc2c1 InChI=1S/C24H30N2O/c1-27-23-12-13-24-20(7-5-8-21(24)19-23)9-6-14-25-15-17-26(18-16-25)22-10-3-2-4-11-22/h2-4,7,10-13,19H,5-6,8-9,14-18H2,1H3 SBMUIESOBCIJNY-UHFFFAOYSA-N 50043887 1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL8453 D(2) dopamine receptor Rattus norvegicus 777 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043887&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14978224 103975261 CHEMBL8453 ZINC25986245 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070484 COc1ccc2C(CCCN3CCN(CC3)c3cc(OC)ccc3OC)=CCCc2c1 InChI=1S/C26H34N2O3/c1-29-22-9-11-24-20(6-4-7-21(24)18-22)8-5-13-27-14-16-28(17-15-27)25-19-23(30-2)10-12-26(25)31-3/h6,9-12,18-19H,4-5,7-8,13-17H2,1-3H3 PEPKMSKYYWMLTI-UHFFFAOYSA-N 50043883 1-(2,5-Dimethoxy-phenyl)-4-[3-(6-methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL267222 D(2) dopamine receptor Rattus norvegicus 201 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043883&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14978227 103975257 CHEMBL267222 ZINC25988184 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070488 COc1cccc2CCC=C(CCCN3CCN(CC3)c3cccc(Cl)c3)c12 InChI=1S/C24H29ClN2O/c1-28-23-12-3-8-19-6-2-7-20(24(19)23)9-5-13-26-14-16-27(17-15-26)22-11-4-10-21(25)18-22/h3-4,7-8,10-12,18H,2,5-6,9,13-17H2,1H3 PFBQXBPMJULGOX-UHFFFAOYSA-N 50043886 1-(3-Chloro-phenyl)-4-[3-(8-methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL266765 D(2) dopamine receptor Rattus norvegicus 484 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043886&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14978231 103975260 CHEMBL266765 ZINC25984725 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070489 COc1ccccc1N1CCN(CCCC2=CCCc3cccc(OC)c23)CC1 InChI=1S/C25H32N2O2/c1-28-23-13-4-3-12-22(23)27-18-16-26(17-19-27)15-7-11-21-9-5-8-20-10-6-14-24(29-2)25(20)21/h3-4,6,9-10,12-14H,5,7-8,11,15-19H2,1-2H3 VMCRBYMNSSSNGZ-UHFFFAOYSA-N 50043892 1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL8536 D(2) dopamine receptor Rattus norvegicus 17.4 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043892&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14978228 103975266 CHEMBL8536 ZINC25987219 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070491 COc1ccc2C(CCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)=CCCc2c1 InChI=1S/C25H29F3N2O/c1-31-23-10-11-24-19(5-2-6-20(24)17-23)7-4-12-29-13-15-30(16-14-29)22-9-3-8-21(18-22)25(26,27)28/h3,5,8-11,17-18H,2,4,6-7,12-16H2,1H3 RTTLUSMWCVHYGQ-UHFFFAOYSA-N 50043889 1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL8507 D(2) dopamine receptor Rattus norvegicus 1290 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043889&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14978226 103975263 CHEMBL8507 ZINC25988192 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070493 COc1cccc2CCC=C(CCCN3CCN(CC3)c3ccccc3)c12 InChI=1S/C24H30N2O/c1-27-23-14-6-10-20-8-5-9-21(24(20)23)11-7-15-25-16-18-26(19-17-25)22-12-3-2-4-13-22/h2-4,6,9-10,12-14H,5,7-8,11,15-19H2,1H3 PLKWFBNSIMCFTD-UHFFFAOYSA-N 50043893 1-[3-(8-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL8593 D(2) dopamine receptor Rattus norvegicus 303 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043893&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14978230 103975267 CHEMBL8593 ZINC25987421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50070494 COc1ccc2C(CCCN3CCN(CC3)c3ccccn3)=CCCc2c1 InChI=1S/C23H29N3O/c1-27-21-10-11-22-19(6-4-7-20(22)18-21)8-5-13-25-14-16-26(17-15-25)23-9-2-3-12-24-23/h2-3,6,9-12,18H,4-5,7-8,13-17H2,1H3 YFQVEXXLLCTPSB-UHFFFAOYSA-N 50043881 1-[3-(6-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL417421 D(2) dopamine receptor Rattus norvegicus 778 ChEMBL 10.1021/jm00027a012 10.7270/Q2NP23GP 8289207 Perrone, R; Berardi, F; Colabufo, NA; Tortorella, V; Fiorentini, F; Olgiati, V; Vanotti, E; Govoni, S Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50043881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50043881&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44265483 103975255 CHEMBL417421 ZINC25985532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075168 OCCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 InChI=1S/C16H19FN2O/c17-10-2-4-13-12(8-10)16-14(18-13)9-11-3-5-15(16)19(11)6-1-7-20/h2,4,8,11,15,18,20H,1,3,5-7,9H2 QJONDYJKMHCZCZ-UHFFFAOYSA-N 50046449 3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-propanol::CHEMBL119409 D(2) dopamine receptor Rattus norvegicus 37300 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046449&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149411 103977234 CHEMBL119409 ZINC27104415 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075169 C(\C=C\c1ccccc1)N1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C22H22N2/c1-2-7-16(8-3-1)9-6-14-24-17-12-13-21(24)22-18-10-4-5-11-19(18)23-20(22)15-17/h1-11,17,21,23H,12-15H2/b9-6+ IAERDBQBVRZFGA-RMKNXTFCSA-N 50046451 15-[3-phenyl-(E)-2-propenyl]-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL119485 D(2) dopamine receptor Rattus norvegicus 2460 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046451&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149407 103977236 CHEMBL119485 ZINC27103681 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075172 C(CCc1ccccc1)CN1C2CCC1c1c(C2)n(Cc2ccccc2)c2ccccc12 InChI=1S/C30H32N2/c1-3-11-23(12-4-1)13-9-10-20-31-25-18-19-28(31)30-26-16-7-8-17-27(26)32(29(30)21-25)22-24-14-5-2-6-15-24/h1-8,11-12,14-17,25,28H,9-10,13,18-22H2 FIRXDZAUSDKQNJ-UHFFFAOYSA-N 50046453 1-[9-benzyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-phenylbutane::CHEMBL331500 D(2) dopamine receptor Rattus norvegicus 1830 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149420 103977238 CHEMBL331500 ZINC27102563 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075173 C(CN1C2CCC1c1c(C2)[nH]c2ccccc12)N1Cc2ccccc2C1 InChI=1S/C23H25N3/c1-2-6-17-15-25(14-16(17)5-1)11-12-26-18-9-10-22(26)23-19-7-3-4-8-20(19)24-21(23)13-18/h1-8,18,22,24H,9-15H2 CTQHCPZZSHQSPL-UHFFFAOYSA-N 50046456 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-2-(2,3-dihydro-1H-2-isoindolyl)ethane::CHEMBL116207 D(2) dopamine receptor Rattus norvegicus 2000 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149417 103977241 CHEMBL116207 ZINC22778554 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075177 CCCN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C16H20N2/c1-2-9-18-11-7-8-15(18)16-12-5-3-4-6-13(12)17-14(16)10-11/h3-6,11,15,17H,2,7-10H2,1H3 KUFOCIILMPNBEI-UHFFFAOYSA-N 50046458 15-propyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL119495 D(2) dopamine receptor Rattus norvegicus 11200 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149391 103977243 CHEMBL119495 ZINC27106376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075181 Fc1ccc2[nH]c3CC4CCC(N4CCCc4cccnc4)c3c2c1 InChI=1S/C21H22FN3/c22-15-5-7-18-17(11-15)21-19(24-18)12-16-6-8-20(21)25(16)10-2-4-14-3-1-9-23-13-14/h1,3,5,7,9,11,13,16,20,24H,2,4,6,8,10,12H2 JHJZSVHCUXVYQO-UHFFFAOYSA-N 50046452 1-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-3-(3-pyridyl)propane::CHEMBL325168 D(2) dopamine receptor Rattus norvegicus 12200 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046452&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149414 103977237 CHEMBL325168 ZINC27098525 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075185 Fc1ccc2[nH]c3CC4CCC(N4CCCCc4ccccc4)c3c2c1 InChI=1S/C23H25FN2/c24-17-9-11-20-19(14-17)23-21(25-20)15-18-10-12-22(23)26(18)13-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9,11,14,18,22,25H,4-5,8,10,12-13,15H2 SOTXRBRECFGWCR-UHFFFAOYSA-N 50046465 1-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-phenylbutane::CHEMBL35711 D(2) dopamine receptor Rattus norvegicus 769.0 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646141 103977250 CHEMBL35711 ZINC13827320 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075186 CN(CCN1C2CCC1c1c(C2)[nH]c2ccccc12)CCc1ccc(Cl)c(Cl)c1 InChI=1S/C24H27Cl2N3/c1-28(11-10-16-6-8-19(25)20(26)14-16)12-13-29-17-7-9-23(29)24-18-4-2-3-5-21(18)27-22(24)15-17/h2-6,8,14,17,23,27H,7,9-13,15H2,1H3 ORNKWELBWBJVHW-UHFFFAOYSA-N 50046464 1N-(3,4-dichlorophenethyl)-1N-methyl-2-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-ethanamine::CHEMBL116710 D(2) dopamine receptor Rattus norvegicus 2530 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046464&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149386 103977249 CHEMBL116710 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075189 CC(C)n1c2CC3CCC(N3CCCCc3ccccc3)c2c2ccccc12 InChI=1S/C26H32N2/c1-19(2)28-23-14-7-6-13-22(23)26-24-16-15-21(18-25(26)28)27(24)17-9-8-12-20-10-4-3-5-11-20/h3-7,10-11,13-14,19,21,24H,8-9,12,15-18H2,1-2H3 DPCGTROJFNXOEE-UHFFFAOYSA-N 50046466 1-[9-isopropyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-phenylbutane::CHEMBL119889 D(2) dopamine receptor Rattus norvegicus 2640 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149419 103977251 CHEMBL119889 ZINC27105222 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075193 CN(CCN1C2CCC1c1c(C2)[nH]c2ccccc12)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C24H25Cl2N3O/c1-28(23(30)13-15-6-8-18(25)19(26)12-15)10-11-29-16-7-9-22(29)24-17-4-2-3-5-20(17)27-21(24)14-16/h2-6,8,12,16,22,27H,7,9-11,13-14H2,1H3 MGJFUWQIAPYYNE-UHFFFAOYSA-N 50046448 1N-{2-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]ethyl}-1N-methyl-2-(3,4-dichlorophenyl)acetamide::CHEMBL117748 D(2) dopamine receptor Rattus norvegicus 3790 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046448&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149384 103977233 CHEMBL117748 ZINC27101549 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075195 Fc1ccc2[nH]c3CC4CCC(N4CCCN4C(=O)c5ccccc5C4=O)c3c2c1 InChI=1S/C24H22FN3O2/c25-14-6-8-19-18(12-14)22-20(26-19)13-15-7-9-21(22)27(15)10-3-11-28-23(29)16-4-1-2-5-17(16)24(28)30/h1-2,4-6,8,12,15,21,26H,3,7,9-11,13H2 UWOJGRHXHUGQNA-UHFFFAOYSA-N 50046462 2-{3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propyl}-1,3-isoindolinedione::CHEMBL119725 D(2) dopamine receptor Rattus norvegicus 12300 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149416 103977247 CHEMBL119725 ZINC27102363 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075198 Clc1ccc(CCN2C3CCC2c2c(C3)[nH]c3ccccc23)cc1Cl InChI=1S/C21H20Cl2N2/c22-16-7-5-13(11-17(16)23)9-10-25-14-6-8-20(25)21-15-3-1-2-4-18(15)24-19(21)12-14/h1-5,7,11,14,20,24H,6,8-10,12H2 KQHWFSJEUGZFOE-UHFFFAOYSA-N 50046457 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-2-(3,4-dichlorophenyl)ethane::CHEMBL325619 D(2) dopamine receptor Rattus norvegicus 3430 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149409 103977242 CHEMBL325619 ZINC27102789 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075200 C(Cc1ccccc1)N1C2CCC1c1c(C2)n(Cc2ccccc2)c2ccccc12 InChI=1S/C28H28N2/c1-3-9-21(10-4-1)17-18-29-23-15-16-26(29)28-24-13-7-8-14-25(24)30(27(28)19-23)20-22-11-5-2-6-12-22/h1-14,23,26H,15-20H2 CIMSZEBDSUDLPA-UHFFFAOYSA-N 50046470 1-[9-benzyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-2-phenylethane::CHEMBL118665 D(2) dopamine receptor Rattus norvegicus 1620 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149422 103977255 CHEMBL118665 ZINC27105883 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075203 O=C1N(CCN2C3CCC2c2c(C3)[nH]c3ccccc23)C(=O)c2ccccc12 InChI=1S/C23H21N3O2/c27-22-15-5-1-2-6-16(15)23(28)26(22)12-11-25-14-9-10-20(25)21-17-7-3-4-8-18(17)24-19(21)13-14/h1-8,14,20,24H,9-13H2 UVQGFDQHVVFXBZ-UHFFFAOYSA-N 50046472 2-{2-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]ethyl}-1,3-isoindolinedione::CHEMBL119698 D(2) dopamine receptor Rattus norvegicus 52100 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149415 103977257 CHEMBL119698 ZINC27105764 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075207 O=C1CC2(CCCC2)CC(=O)N1CCCCN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C26H33N3O2/c30-23-16-26(11-3-4-12-26)17-24(31)29(23)14-6-5-13-28-18-9-10-22(28)25-19-7-1-2-8-20(19)27-21(25)15-18/h1-2,7-8,18,22,27H,3-6,9-17H2 JAKRKKAOZPPTDH-UHFFFAOYSA-N 50046473 8-{4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione::CHEMBL285203 D(2) dopamine receptor Rattus norvegicus 3000 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646180 103977258 CHEMBL285203 ZINC13861334 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075209 Cn1c2CC3CCC(N3CCCCc3ccccc3)c2c2ccccc12 InChI=1S/C24H28N2/c1-25-21-13-6-5-12-20(21)24-22-15-14-19(17-23(24)25)26(22)16-8-7-11-18-9-3-2-4-10-18/h2-6,9-10,12-13,19,22H,7-8,11,14-17H2,1H3 WSPJJPNQUVUIAC-UHFFFAOYSA-N 50046471 1-[9-methyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-phenylbutane::CHEMBL119075 D(2) dopamine receptor Rattus norvegicus 1820 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149381 103977256 CHEMBL119075 ZINC27105453 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075212 Fc1ccc(CCCCN2C3CCC2c2c(C3)[nH]c3ccccc23)cc1 InChI=1S/C23H25FN2/c24-17-10-8-16(9-11-17)5-3-4-14-26-18-12-13-22(26)23-19-6-1-2-7-20(19)25-21(23)15-18/h1-2,6-11,18,22,25H,3-5,12-15H2 TYLIVIWKWHWCFT-UHFFFAOYSA-N 50046479 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(4-fluorophenyl)butane::CHEMBL38152 D(2) dopamine receptor Rattus norvegicus 1160 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646139 103977264 CHEMBL38152 ZINC13861330 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075216 Fc1ccc(cc1)C(=O)CCCN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C23H23FN2O/c24-16-9-7-15(8-10-16)22(27)6-3-13-26-17-11-12-21(26)23-18-4-1-2-5-19(18)25-20(23)14-17/h1-2,4-5,7-10,17,21,25H,3,6,11-14H2 CEDSKJUGADVONS-UHFFFAOYSA-N 50046475 4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::CHEMBL36645 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046475&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149406 103977260 CHEMBL36645 ZINC13827312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075219 C(N1C2CCC1c1c(C2)[nH]c2ccccc12)c1ccccc1 InChI=1S/C20H20N2/c1-2-6-14(7-3-1)13-22-15-10-11-19(22)20-16-8-4-5-9-17(16)21-18(20)12-15/h1-9,15,19,21H,10-13H2 PQZAXDIYQMDNRT-UHFFFAOYSA-N 50046480 15-benzyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL118288 D(2) dopamine receptor Rattus norvegicus 3650 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046480&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149393 103977265 CHEMBL118288 ZINC12356047 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075222 Fc1ccc2[nH]c3CC4CCC(N4Cc4ccccc4I)c3c2c1 InChI=1S/C20H18FIN2/c21-13-5-7-17-15(9-13)20-18(23-17)10-14-6-8-19(20)24(14)11-12-3-1-2-4-16(12)22/h1-5,7,9,14,19,23H,6,8,10-11H2 CNZSXTHEHFCADJ-UHFFFAOYSA-N 50046467 2-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-ylmethyl]phenyl iodide::CHEMBL323910 D(2) dopamine receptor Rattus norvegicus 5310 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149413 103977252 CHEMBL323910 ZINC27103418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075223 CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C14H16N2/c1-16-9-6-7-13(16)14-10-4-2-3-5-11(10)15-12(14)8-9/h2-5,9,13,15H,6-8H2,1H3 WYQXXIUOFPTASR-UHFFFAOYSA-N 50046461 15-methyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL118276 D(2) dopamine receptor Rattus norvegicus 16600 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046461&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 356862 103977246 CHEMBL118276 ZINC01612418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075224 Clc1ccc(OCCN2C3CCC2c2c(C3)[nH]c3ccccc23)cc1 InChI=1S/C21H21ClN2O/c22-14-5-8-16(9-6-14)25-12-11-24-15-7-10-20(24)21-17-3-1-2-4-18(17)23-19(21)13-15/h1-6,8-9,15,20,23H,7,10-13H2 YZLWLOOEGMGHIW-UHFFFAOYSA-N 50046483 1-(4-chlorophenoxy)-2-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]ethane::CHEMBL324092 D(2) dopamine receptor Rattus norvegicus 530 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149398 103977268 CHEMBL324092 ZINC27092792 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075228 C(CN1C2CCC1c1c(C2)[nH]c2ccccc12)Oc1ccccc1 InChI=1S/C21H22N2O/c1-2-6-16(7-3-1)24-13-12-23-15-10-11-20(23)21-17-8-4-5-9-18(17)22-19(21)14-15/h1-9,15,20,22H,10-14H2 KEWSAZZCCKCVHI-UHFFFAOYSA-N 50046487 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-2-phenoxyethane::CHEMBL332593 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046487&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149397 103977272 CHEMBL332593 ZINC12356104 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075230 Fc1ccc2[nH]c3CC4CCC(N4)c3c2c1 InChI=1S/C13H13FN2/c14-7-1-3-10-9(5-7)13-11-4-2-8(15-11)6-12(13)16-10/h1,3,5,8,11,15-16H,2,4,6H2 BHBOTTMNPGXYAZ-UHFFFAOYSA-N 50046477 5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL331006 D(2) dopamine receptor Rattus norvegicus 36600 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046477&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646123 103977262 CHEMBL331006 ZINC12355902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056592 Fc1ccc(cc1)C(=O)CCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 InChI=1S/C23H22F2N2O/c24-15-5-3-14(4-6-15)22(28)2-1-11-27-17-8-10-21(27)23-18-12-16(25)7-9-19(18)26-20(23)13-17/h3-7,9,12,17,21,26H,1-2,8,10-11,13H2 SWEUQJQJCWSLBM-UHFFFAOYSA-N 50036648 (7R,10S)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::(7S,10R)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::CHEMBL38151 D(2) dopamine receptor Rattus norvegicus 99.3 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646133 103944289 CHEMBL38151 ZINC13827314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071084 CCCN(CCC)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3 DSEPKSLFXGYPIU-UHFFFAOYSA-N 50035320 (+/-)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL304426 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 178081 103943346 CHEMBL304426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071085 CCCN(CCC)[C@@H]1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m1/s1 ASXGJMSKWNBENU-CQSZACIVSA-N 50016777 ((R)-8-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium::(8-Hydroxyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol ((R)-OH-DPAT)::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol(8-OH-DPAT)::CHEMBL26998::R-(+)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol D(2) dopamine receptor Rattus norvegicus 826 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603866 103928146 73364 CHEMBL26998 ZINC03870312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071086 CN(C)[C@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C14H18N2/c1-16(2)11-5-3-10-4-6-14-12(7-8-15-14)13(10)9-11/h4,6-8,11,15H,3,5,9H2,1-2H3/t11-/m0/s1 HENBLLXAHPTGHX-NSHDSACASA-N 50044235 CHEMBL292274::Dimethyl-(S)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::S-(-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 1580 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044235&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14547415 103975558 CHEMBL292274 ZINC05965209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071088 CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C(C)=O)c3c2C1 InChI=1S/C20H28N2O/c1-4-10-22(11-5-2)16-8-6-15-7-9-19-20(17(15)12-16)18(13-21-19)14(3)23/h7,9,13,16,21H,4-6,8,10-12H2,1-3H3/t16-/m1/s1 VMXHWDJFMZJHSQ-MRXNPFEDSA-N 50044237 CHEMBL65274::R-(+)-1-(8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-ethanone D(2) dopamine receptor Rattus norvegicus 382.0 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044237&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44305165 103975560 CHEMBL65274 ZINC13741708 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071089 CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1 GKDJCOLVXBCNNK-HNNXBMFYSA-N 50035307 CHEMBL302171::Dipropyl-(S)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::S-(-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 146 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035307&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10468376 103943333 CHEMBL302171 ZINC13738689 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071092 CN(C)[C@@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C14H18N2/c1-16(2)11-5-3-10-4-6-14-12(7-8-15-14)13(10)9-11/h4,6-8,11,15H,3,5,9H2,1-2H3/t11-/m1/s1 HENBLLXAHPTGHX-LLVKDONJSA-N 50044236 CHEMBL303339::Dimethyl-(R)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::R-(+)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 170 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044236&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14547414 103975559 CHEMBL303339 ZINC03798324 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071094 CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3 GKDJCOLVXBCNNK-UHFFFAOYSA-N 50035329 (+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine::CHEMBL65196::Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 156 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035329&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13096730 103943355 CHEMBL65196 ZINC03798326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071096 CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C(C)=O)c3c2C1 InChI=1S/C20H28N2O/c1-4-10-22(11-5-2)16-8-6-15-7-9-19-20(17(15)12-16)18(13-21-19)14(3)23/h7,9,13,16,21H,4-6,8,10-12H2,1-3H3/t16-/m0/s1 VMXHWDJFMZJHSQ-INIZCTEOSA-N 50044238 CHEMBL63449::S-(-)-1-(8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indol-1-yl)-ethanone D(2) dopamine receptor Rattus norvegicus 3592.0 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044238&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44305180 103975561 CHEMBL63449 ZINC13741709 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071099 CCCN(CCC)C1CCc2cc3cc[nH]c3cc2C1 InChI=1S/C18H26N2/c1-3-9-20(10-4-2)17-6-5-14-11-15-7-8-19-18(15)13-16(14)12-17/h7-8,11,13,17,19H,3-6,9-10,12H2,1-2H3 PJRCRPZYNQZZBV-UHFFFAOYSA-N 50037271 CHEMBL305341::Dipropyl-(5,6,7,8-tetrahydro-1H-benzo[f]indol-7-yl)-amine D(2) dopamine receptor Rattus norvegicus 350 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037271&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129733 103944819 CHEMBL305341 ZINC05833126 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071102 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 1357 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071103 CCCN(CCC)[C@H]1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1 ASXGJMSKWNBENU-AWEZNQCLSA-N 50011247 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol; hydrobromide::CHEMBL41436::CHEMBL541621::S-(-)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol D(2) dopamine receptor Rattus norvegicus 5072 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10125797 103923882 CHEMBL541621CHEMBL41436 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071111 CN(C)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C14H18N2/c1-16(2)11-5-3-10-4-6-14-12(7-8-15-14)13(10)9-11/h4,6-8,11,15H,3,5,9H2,1-2H3 HENBLLXAHPTGHX-UHFFFAOYSA-N 50017520 (+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine::CHEMBL413105::Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129503 103928788 CHEMBL413105 ZINC05965209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071113 CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1 GKDJCOLVXBCNNK-OAHLLOKOSA-N 50035330 CHEMBL302172::Dipropyl-(R)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::R-(+)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10858566 103943356 CHEMBL302172 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071194 CN(C)c1ccc(cc1)-c1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C25H26N2O2/c1-26(2)19-7-4-15(5-8-19)18-12-17-10-11-27(3)21-14-16-6-9-22(28)25(29)24(16)20(13-18)23(17)21/h4-9,12-13,21,28-29H,10-11,14H2,1-3H3/t21-/m1/s1 BSBMMXOBOAVGQD-OAQYLSRUSA-N 50251029 (R)-(-)-2-(4-N,N-Dimethylaminophenyl)-apomorphine dihydrochloride::CHEMBL458587 D(2) dopamine receptor Rattus norvegicus 242 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251029&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567294 104104363 CHEMBL458587 ZINC40392711 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071195 CN1CCc2cc(C)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C18H19NO2/c1-10-7-12-5-6-19(2)14-9-11-3-4-15(20)18(21)17(11)13(8-10)16(12)14/h3-4,7-8,14,20-21H,5-6,9H2,1-2H3/t14-/m1/s1 QRJZCXSRTBCYIW-CQSZACIVSA-N 50251028 (R)-(-)-2-Methyl-apomorphine hydrochloride::CHEMBL507567::CHEMBL557547 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567292 104104362 CHEMBL557547CHEMBL507567 ZINC40846701 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071196 CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccc(O)cc1 InChI=1S/C23H21NO3/c1-24-9-8-15-10-16(13-2-5-17(25)6-3-13)11-18-21(15)19(24)12-14-4-7-20(26)23(27)22(14)18/h2-7,10-11,19,25-27H,8-9,12H2,1H3/t19-/m1/s1 IEYKUJATGFZIHM-LJQANCHMSA-N 50251027 (R)-(-)-2-(4-Hydroxyphenyl)-apomorphine hydrochloride::CHEMBL458579::CHEMBL517028 D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11639064 104104361 CHEMBL517028CHEMBL458579 ZINC35982742 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071197 CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1 InChI=1S/C23H21NO2/c1-24-10-9-16-11-17(14-5-3-2-4-6-14)12-18-21(16)19(24)13-15-7-8-20(25)23(26)22(15)18/h2-8,11-12,19,25-26H,9-10,13H2,1H3/t19-/m1/s1 NJWHLJABYCIZPL-LJQANCHMSA-N 50251026 (R)-(-)-2-Phenyl-apomorphine hydrochloride::CHEMBL458397::CHEMBL465054 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11515697 104104360 CHEMBL458397CHEMBL465054 ZINC40863607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071203 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 29644 (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride::APOMORPHINE HYDROCHLORIDE::APOMORPHINE HYDROCHLORIDE HEMIHYDRATE::MLS000069811::SMR000059235::cid_6852399 D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 252614856 DB00714 ZINC00446541 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50071204 CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1cccc2c1oc1ccccc21 InChI=1S/C29H23NO3/c1-30-12-11-17-13-18(19-6-4-7-21-20-5-2-3-8-25(20)33-29(19)21)14-22-26(17)23(30)15-16-9-10-24(31)28(32)27(16)22/h2-10,13-14,23,31-32H,11-12,15H2,1H3/t23-/m1/s1 XIJMIVGGWJHATO-HSZRJFAPSA-N 50251034 (R)-(-)-2-(4-dibenzo-furanyl)-apomorphine hydrochloride::CHEMBL465696 D(2) dopamine receptor Rattus norvegicus 1627 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567298 104104365 CHEMBL465696 ZINC40880686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50073438 C[C@H]1CN(CC[C@H](O)C2CCCCC2)CC[C@@]1(C)c1cccc(O)c1 InChI=1S/C22H35NO2/c1-17-16-23(13-11-21(25)18-7-4-3-5-8-18)14-12-22(17,2)19-9-6-10-20(24)15-19/h6,9-10,15,17-18,21,24-25H,3-5,7-8,11-14,16H2,1-2H3/t17-,21-,22+/m0/s1 LVVHEFJXPXAUDD-BULFRSBZSA-N 50045775 (3R,4R)3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol::3-((3R,4R)-1-((S)-3-cyclohexyl-3-hydroxypropyl)-3,4-dimethylpiperidin-4-yl)phenol::3-[(3R,4R)-1-((S)-3-Cyclohexyl-3-hydroxy-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol::3-[1-(3-Cyclohexyl-3-hydroxy-propyl)-3,4-dimethyl-piperidin-4-yl]-phenol::CHEMBL300662::LY-255582 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00072a002 10.7270/Q2R78D9W 8410999 Mitch, CH; Leander, JD; Mendelsohn, LG; Shaw, WN; Wong, DT; Cantrell, BE; Johnson, BG; Reel, JK; Snoddy, JD; Takemori, AE Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9906198 103976648 CHEMBL300662 C03491 ZINC03783617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056593 Fc1ccc(cc1)C(=O)CCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 InChI=1S/C23H22F2N2O/c24-15-5-3-14(4-6-15)22(28)2-1-11-27-17-8-10-21(27)23-18-12-16(25)7-9-19(18)26-20(23)13-17/h3-7,9,12,17,21,26H,1-2,8,10-11,13H2 SWEUQJQJCWSLBM-UHFFFAOYSA-N 50036648 (7R,10S)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::(7S,10R)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::CHEMBL38151 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646133 103944289 CHEMBL38151 ZINC13827314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50073548 CN1CCC(=CC1)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C20H18ClFN2/c1-23-10-8-14(9-11-23)19-13-24(17-5-3-16(22)4-6-17)20-7-2-15(21)12-18(19)20/h2-8,12-13H,9-11H2,1H3 VMZWFUNEODYUEN-UHFFFAOYSA-N 50002015 5-Chloro-1-(4-fluoro-phenyl)-3-(1-methyl-1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole::CHEMBL12507 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm00072a006 10.7270/Q2GQ6WVF 8411003 Palm, J; Bogeso, KP; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002015&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15648963 103916368 CHEMBL12507 ZINC13452416 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50073549 OCCN1CCN(CC1)[C@@H]1C[C@H](c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2/t19-,21+/m0/s1 JSBWGXQXCRYYTG-PZJWPPBQSA-N 50019966 2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL95636::Tefludazine D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm00072a006 10.7270/Q2GQ6WVF 8411003 Palm, J; Bogeso, KP; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71240 103930889 CHEMBL95636 ZINC22463345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50073550 CN1CCC(CC1)C1=CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C21H21ClFN/c1-24-10-8-15(9-11-24)20-13-19(14-2-5-17(23)6-3-14)18-7-4-16(22)12-21(18)20/h2-7,12-13,15,19H,8-11H2,1H3 MVRLLCOTIWCMOM-UHFFFAOYSA-N 50045822 4-[6-Chloro-3-(4-fluoro-phenyl)-3H-inden-1-yl]-1-methyl-piperidine::CHEMBL317982 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm00072a006 10.7270/Q2GQ6WVF 8411003 Palm, J; Bogeso, KP; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15648961 103976695 CHEMBL317982 ZINC13833071 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50073556 CN1CCN(CC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C20H22ClFN2/c1-23-8-10-24(11-9-23)20-13-18(14-2-5-16(22)6-3-14)17-7-4-15(21)12-19(17)20/h2-7,12,18,20H,8-11,13H2,1H3 JBFVCXODUHNOEN-UHFFFAOYSA-N 50029413 1-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-4-methyl-piperazine::CHEMBL318714 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00072a006 10.7270/Q2GQ6WVF 8411003 Palm, J; Bogeso, KP; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029413&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44329358 103938483 CHEMBL318714 ZINC22937780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50073558 CN1CCN(CC1)[C@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m0/s1 XRYLGRGAWQSVQW-KRWDZBQOSA-N 50007568 1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL303313::OCTOCLOTHEPIN-S D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm00072a006 10.7270/Q2GQ6WVF 8411003 Palm, J; Bogeso, KP; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12765746 103920838 CHEMBL303313 ZINC19368911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50073554 CN1CCC(=CC1)C1=CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C21H19ClFN/c1-24-10-8-15(9-11-24)20-13-19(14-2-5-17(23)6-3-14)18-7-4-16(22)12-21(18)20/h2-8,12-13,19H,9-11H2,1H3 YZVNDQNRVZGAEI-UHFFFAOYSA-N 50045823 4-[6-Chloro-3-(4-fluoro-phenyl)-3H-inden-1-yl]-1-methyl-1,2,3,6-tetrahydro-pyridine::CHEMBL319810 D(2) dopamine receptor Rattus norvegicus 5.1 ChEMBL 10.1021/jm00072a006 10.7270/Q2GQ6WVF 8411003 Palm, J; Bogeso, KP; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15648962 103976696 CHEMBL319810 ZINC13833073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076974 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 265 ChEMBL 10.1021/jm00062a028 10.7270/Q29W0DJH 8496920 Cliffe, IA; Brightwell, CI; Fletcher, A; Forster, EA; Mansell, HL; Reilly, Y; Routledge, C; White, AC Wyeth Research (UK) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076266 Oc1ccc2[nH]cc(C3=CCN(CCCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C26H25N3O3S/c30-20-8-9-23-21(16-20)22(17-27-23)18-10-14-28(15-11-18)12-3-13-29-24-6-1-4-19-5-2-7-25(26(19)24)33(29,31)32/h1-2,4-10,16-17,27,30H,3,11-15H2 PXLJHRMPQADPTF-UHFFFAOYSA-N 50047090 3-{1-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]isothiazol-2-yl)-propyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1H-indol-5-ol::CHEMBL19652 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047090&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646682 103977778 CHEMBL19652 ZINC13826819 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076268 Fc1cccc2[nH]cc(CC3CCN(CCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c12 InChI=1S/C26H26FN3O2S/c27-21-6-3-7-22-25(21)20(17-28-22)16-18-10-12-29(13-11-18)14-15-30-23-8-1-4-19-5-2-9-24(26(19)23)33(30,31)32/h1-9,17-18,28H,10-16H2 JQNPXPMENUSCSJ-UHFFFAOYSA-N 50047094 2-{2-[4-(4-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL275354 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047094&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646692 103977782 CHEMBL275354 ZINC13826839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076275 Fc1ccc2[nH]cc(CC3CCN(CCN4c5cccc6CCCN(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C25H29FN4O2S/c26-21-6-7-23-22(16-21)20(17-27-23)15-18-8-11-28(12-9-18)13-14-29-24-5-1-3-19-4-2-10-30(25(19)24)33(29,31)32/h1,3,5-7,16-18,27H,2,4,8-15H2 NZUSTSFFNOEAHE-UHFFFAOYSA-N 50047098 1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-4,5-dihydro-1H,3H-2-thia-1,2a-diaza-acenaphthylene 2,2-dioxide::CHEMBL274728::RP-68303 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047098&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 183775 103977786 CHEMBL274728 ZINC00597802 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076279 Fc1ccc2[nH]cc(CC3CCNCC3)c2c1 InChI=1S/C14H17FN2/c15-12-1-2-14-13(8-12)11(9-17-14)7-10-3-5-16-6-4-10/h1-2,8-10,16-17H,3-7H2 FFWFFOAMLOOINZ-UHFFFAOYSA-N 50029154 5-Fluoro-3-piperidin-4-ylmethyl-1H-indole::CHEMBL278080 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029154&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11287716 103938232 CHEMBL278080 ZINC13826856 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076280 COc1ccc2[nH]cc(C3=CCN(CCCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C27H27N3O3S/c1-33-21-9-10-24-22(17-21)23(18-28-24)19-11-15-29(16-12-19)13-4-14-30-25-7-2-5-20-6-3-8-26(27(20)25)34(30,31)32/h2-3,5-11,17-18,28H,4,12-16H2,1H3 FNHGKJPJDDUZIM-UHFFFAOYSA-N 50047099 2-{3-[4-(5-Methoxy-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL18212 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047099&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646681 103977787 CHEMBL18212 ZINC13826817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076284 O=S1(=O)N(CCCN2CCC(CC2)c2c[nH]c3ccccc23)c2cccc3cccc1c23 InChI=1S/C26H27N3O2S/c30-32(31)25-11-4-7-20-6-3-10-24(26(20)25)29(32)15-5-14-28-16-12-19(13-17-28)22-18-27-23-9-2-1-8-21(22)23/h1-4,6-11,18-19,27H,5,12-17H2 ZTDOROPEEBAJPY-UHFFFAOYSA-N 50047095 2-{3-[4-(1H-Indol-3-yl)-piperidin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL281808 D(2) dopamine receptor Rattus norvegicus 4.6 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047095&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646688 103977783 CHEMBL281808 ZINC13826835 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076285 CC(=O)n1cc(C2=CCN(CCCN3c4cccc5cccc(c45)S3(=O)=O)CC2)c2ccccc12 InChI=1S/C28H27N3O3S/c1-20(32)30-19-24(23-9-2-3-10-25(23)30)21-13-17-29(18-14-21)15-6-16-31-26-11-4-7-22-8-5-12-27(28(22)26)35(31,33)34/h2-5,7-13,19H,6,14-18H2,1H3 BAWIYSVYEJNRCP-UHFFFAOYSA-N 50047087 1-(3-{1-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]isothiazol-2-yl)-propyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-indol-1-yl)-ethanone::CHEMBL279414 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047087&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646699 103977775 CHEMBL279414 ZINC13826829 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076287 Fc1ccc2[nH]cc(CC3CCN(CCN4c5ccccc5-c5ccccc5S4(=O)=O)CC3)c2c1 InChI=1S/C28H28FN3O2S/c29-22-9-10-26-25(18-22)21(19-30-26)17-20-11-13-31(14-12-20)15-16-32-27-7-3-1-5-23(27)24-6-2-4-8-28(24)35(32,33)34/h1-10,18-20,30H,11-17H2 UIVOCYXCNVVBDJ-UHFFFAOYSA-N 50047084 10-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-10H-9-thia-10-aza-phenanthrene 9,9-dioxide::CHEMBL19226 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047084&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646713 103977772 CHEMBL19226 ZINC13826854 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076288 Fc1ccc2[nH]cc(CC3CCN(CCN4C(=O)c5cccc6cccc4c56)CC3)c2c1 InChI=1S/C27H26FN3O/c28-21-7-8-24-23(16-21)20(17-29-24)15-18-9-11-30(12-10-18)13-14-31-25-6-2-4-19-3-1-5-22(26(19)25)27(31)32/h1-8,16-18,29H,9-15H2 WRHKYIREOIGMLR-UHFFFAOYSA-N 50047102 1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-1H-benzo[cd]indol-2-one::CHEMBL18625 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047102&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646709 103977790 CHEMBL18625 ZINC00597801 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076300 Cn1cc(C2=CCN(CCCN3c4cccc5cccc(c45)S3(=O)=O)CC2)c2ccccc12 InChI=1S/C27H27N3O2S/c1-28-19-23(22-9-2-3-10-24(22)28)20-13-17-29(18-14-20)15-6-16-30-25-11-4-7-21-8-5-12-26(27(21)25)33(30,31)32/h2-5,7-13,19H,6,14-18H2,1H3 NKSXAKPRNJHCLU-UHFFFAOYSA-N 50047086 2-{3-[4-(1-Methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL19111 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047086&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646698 103977774 CHEMBL19111 ZINC13826827 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076306 Fc1ccc2[nH]cc(CCC3CCN(CCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C27H28FN3O2S/c28-22-9-10-24-23(17-22)21(18-29-24)8-7-19-11-13-30(14-12-19)15-16-31-25-5-1-3-20-4-2-6-26(27(20)25)34(31,32)33/h1-6,9-10,17-19,29H,7-8,11-16H2 JPJNJAFDFQKIIR-UHFFFAOYSA-N 50047105 2-(2-{4-[2-(5-Fluoro-1H-indol-3-yl)-ethyl]-piperidin-1-yl}-ethyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL18501 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047105&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646691 103977793 CHEMBL18501 ZINC13826837 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075240 C(CCc1cccs1)CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C21H24N2S/c1-2-9-18-17(8-1)21-19(22-18)14-15-10-11-20(21)23(15)12-4-3-6-16-7-5-13-24-16/h1-2,5,7-9,13,15,20,22H,3-4,6,10-12,14H2 MVZQFWPPZDOLHW-UHFFFAOYSA-N 50046450 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(2-thienyl)butane::CHEMBL119867 D(2) dopamine receptor Rattus norvegicus 620 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046450&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149403 103977235 CHEMBL119867 ZINC27104521 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075241 C(CCc1ccccc1)CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C23H26N2/c1-2-8-17(9-3-1)10-6-7-15-25-18-13-14-22(25)23-19-11-4-5-12-20(19)24-21(23)16-18/h1-5,8-9,11-12,18,22,24H,6-7,10,13-16H2 YJWKPDMZHMZMRC-UHFFFAOYSA-N 50046482 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-phenylbutane::CHEMBL38130 D(2) dopamine receptor Rattus norvegicus 733 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046482&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646135 103977267 CHEMBL38130 ZINC13827316 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075246 Fc1ccc2[nH]c3CCN(CCCc4ccncc4)Cc3c2c1 InChI=1S/C19H20FN3/c20-15-3-4-18-16(12-15)17-13-23(11-7-19(17)22-18)10-1-2-14-5-8-21-9-6-14/h3-6,8-9,12,22H,1-2,7,10-11,13H2 HRIFUBQUULPVIJ-UHFFFAOYSA-N 50046488 8-Fluoro-2-(3-pyridin-4-yl-propyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole::CHEMBL442395 D(2) dopamine receptor Rattus norvegicus 6 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44344745 103977273 CHEMBL442395 ZINC12356098 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075249 C(CCc1ccco1)CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C21H24N2O/c1-2-9-18-17(8-1)21-19(22-18)14-15-10-11-20(21)23(15)12-4-3-6-16-7-5-13-24-16/h1-2,5,7-9,13,15,20,22H,3-4,6,10-12,14H2 BBNMJCHVYDPLHH-UHFFFAOYSA-N 50046459 (+)-1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(2-furyl)butane::(+/-)-1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(2-furyl)butane::(-)-1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(2-furyl)butane::1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(2-furyl)butane::CHEMBL117898 D(2) dopamine receptor Rattus norvegicus 1270 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149404 103977244 CHEMBL117898 ZINC13861335 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075254 Fc1ccc2[nH]c3CC4CCC(N4Cc4ccccc4)c3c2c1 InChI=1S/C20H19FN2/c21-14-6-8-17-16(10-14)20-18(22-17)11-15-7-9-19(20)23(15)12-13-4-2-1-3-5-13/h1-6,8,10,15,19,22H,7,9,11-12H2 XNEILRWYILYORS-UHFFFAOYSA-N 50046486 15-benzyl-5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL117567 D(2) dopamine receptor Rattus norvegicus 2420 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046486&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149412 103977271 CHEMBL117567 ZINC27102235 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075255 C(Cc1ccccc1)N1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C21H22N2/c1-2-6-15(7-3-1)12-13-23-16-10-11-20(23)21-17-8-4-5-9-18(17)22-19(21)14-16/h1-9,16,20,22H,10-14H2 ZWVYJKKPUUUTFE-UHFFFAOYSA-N 50046474 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-2-phenylethane::CHEMBL119804 D(2) dopamine receptor Rattus norvegicus 840.0 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149394 103977259 CHEMBL119804 ZINC12356084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075256 Fc1ccc(OCCCN2C3CCC2c2c(C3)[nH]c3ccccc23)cc1 InChI=1S/C22H23FN2O/c23-15-6-9-17(10-7-15)26-13-3-12-25-16-8-11-21(25)22-18-4-1-2-5-19(18)24-20(22)14-16/h1-2,4-7,9-10,16,21,24H,3,8,11-14H2 GHQBNTNSLQFLLN-UHFFFAOYSA-N 50046460 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-3-(4-fluorophenoxy)propane::CHEMBL119811 D(2) dopamine receptor Rattus norvegicus 2100 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046460&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149401 103977245 CHEMBL119811 ZINC27104202 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075259 C(CCc1nccs1)CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C20H23N3S/c1-2-6-16-15(5-1)20-17(22-16)13-14-8-9-18(20)23(14)11-4-3-7-19-21-10-12-24-19/h1-2,5-6,10,12,14,18,22H,3-4,7-9,11,13H2 QQLXEKRGAGDWBA-UHFFFAOYSA-N 50046478 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(1,3-thiazol-2-yl)butane::CHEMBL115582 D(2) dopamine receptor Rattus norvegicus 2230 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046478&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149405 103977263 CHEMBL115582 ZINC13861333 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075265 C(CN1C2CCC1c1c(C2)[nH]c2ccccc12)Cc1ccccc1 InChI=1S/C22H24N2/c1-2-7-16(8-3-1)9-6-14-24-17-12-13-21(24)22-18-10-4-5-11-19(18)23-20(22)15-17/h1-5,7-8,10-11,17,21,23H,6,9,12-15H2 YUKBVZQFSKIXRG-UHFFFAOYSA-N 50046455 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-3-phenylpropane::CHEMBL333840 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046455&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149395 103977240 CHEMBL333840 ZINC27108985 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075266 C(CCN1C2CCC1c1c(C2)[nH]c2ccccc12)COc1ccccc1 InChI=1S/C23H26N2O/c1-2-8-18(9-3-1)26-15-7-6-14-25-17-12-13-22(25)23-19-10-4-5-11-20(19)24-21(23)16-17/h1-5,8-11,17,22,24H,6-7,12-16H2 NEAVYIKGAQRZEX-UHFFFAOYSA-N 50046490 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-phenoxybutane::CHEMBL119047 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046490&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149402 103977275 CHEMBL119047 ZINC27104980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075273 CCN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C15H18N2/c1-2-17-10-7-8-14(17)15-11-5-3-4-6-12(11)16-13(15)9-10/h3-6,10,14,16H,2,7-9H2,1H3 DWODCBQTCVFXPQ-UHFFFAOYSA-N 50046484 15-ethyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL117695 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046484&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149390 103977269 CHEMBL117695 ZINC27101646 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075234 Clc1ccc(OCCN2C3CCC2c2c(C3)[nH]c3ccccc23)cc1Cl InChI=1S/C21H20Cl2N2O/c22-16-7-6-14(12-17(16)23)26-10-9-25-13-5-8-20(25)21-15-3-1-2-4-18(15)24-19(21)11-13/h1-4,6-7,12-13,20,24H,5,8-11H2 NLHVOHXLTQXDSJ-UHFFFAOYSA-N 50046469 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-2-(3,4-dichlorophenoxy)ethane::CHEMBL118289 D(2) dopamine receptor Rattus norvegicus 650 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046469&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149399 103977254 CHEMBL118289 ZINC27102513 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075235 C(CCN1C2CCC1c1c(C2)[nH]c2ccccc12)CCc1ccccc1 InChI=1S/C24H28N2/c1-3-9-18(10-4-1)11-5-2-8-16-26-19-14-15-23(26)24-20-12-6-7-13-21(20)25-22(24)17-19/h1,3-4,6-7,9-10,12-13,19,23,25H,2,5,8,11,14-17H2 YPYBLULGXVPCAF-UHFFFAOYSA-N 50046485 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-5-phenylpentane::CHEMBL332035 D(2) dopamine receptor Rattus norvegicus 677.0 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046485&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149396 103977270 CHEMBL332035 ZINC27108982 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075282 C(COc1ccccc1)CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C22H24N2O/c1-2-7-17(8-3-1)25-14-6-13-24-16-11-12-21(24)22-18-9-4-5-10-19(18)23-20(22)15-16/h1-5,7-10,16,21,23H,6,11-15H2 JSTVGIPYYFTPBE-UHFFFAOYSA-N 50046481 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-3-phenoxypropane::CHEMBL119048 D(2) dopamine receptor Rattus norvegicus 1280 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046481&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149400 103977266 CHEMBL119048 ZINC27104982 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075283 C(CCc1ccccc1)CN1C2CCC1c1c(C2)n(-c2ccccc2)c2ccccc12 InChI=1S/C29H30N2/c1-3-11-22(12-4-1)13-9-10-20-30-24-18-19-27(30)29-25-16-7-8-17-26(25)31(28(29)21-24)23-14-5-2-6-15-23/h1-8,11-12,14-17,24,27H,9-10,13,18-21H2 ZIKSLIAMFOSMMG-UHFFFAOYSA-N 50046489 1-phenyl-4-[9-phenyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::CHEMBL433022 D(2) dopamine receptor Rattus norvegicus 1570 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046489&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149421 103977274 CHEMBL433022 ZINC27105194 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075285 Fc1ccc2[nH]c3CC4CCC(N4CCCN4Cc5ccccc5C4)c3c2c1 InChI=1S/C24H26FN3/c25-18-6-8-21-20(12-18)24-22(26-21)13-19-7-9-23(24)28(19)11-3-10-27-14-16-4-1-2-5-17(16)15-27/h1-2,4-6,8,12,19,23,26H,3,7,9-11,13-15H2 MPKSTKAGDZAZCI-UHFFFAOYSA-N 50046491 1-(2,3-dihydro-1H-2-isoindolyl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::CHEMBL116711 D(2) dopamine receptor Rattus norvegicus 1780 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046491&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149418 103977276 CHEMBL116711 ZINC27107173 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075286 C1CC2NC1Cc1[nH]c3ccccc3c21 InChI=1S/C13H14N2/c1-2-4-10-9(3-1)13-11-6-5-8(14-11)7-12(13)15-10/h1-4,8,11,14-15H,5-7H2 ZUBTZRPXJLZWKF-UHFFFAOYSA-N 50046468 9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL285541 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149426 103977253 CHEMBL285541 ZINC29306978 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075287 C1CC2NC1Cc1c2c2ccccc2n1-c1ccccc1 InChI=1S/C19H18N2/c1-2-6-14(7-3-1)21-17-9-5-4-8-15(17)19-16-11-10-13(20-16)12-18(19)21/h1-9,13,16,20H,10-12H2 MIZKDYBHLUZOTA-UHFFFAOYSA-N 50046463 9-phenyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL118445 D(2) dopamine receptor Rattus norvegicus 10000 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046463&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13078350 103977248 CHEMBL118445 ZINC12356004 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075298 CC\C=C\N1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C17H20N2/c1-2-3-10-19-12-8-9-16(19)17-13-6-4-5-7-14(13)18-15(17)11-12/h3-7,10,12,16,18H,2,8-9,11H2,1H3/b10-3+ IGDYPUKNLMTHLR-XCVCLJGOSA-N 50046476 15-[(E)-1-butenyl]-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL325845 D(2) dopamine receptor Rattus norvegicus 710 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046476&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149392 103977261 CHEMBL325845 ZINC27101651 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076310 Fc1ccc2[nH]c(CC3CCN(CCN4c5cccc6cccc(c56)S4(=O)=O)CC3)cc2c1 InChI=1S/C26H26FN3O2S/c27-21-7-8-23-20(16-21)17-22(28-23)15-18-9-11-29(12-10-18)13-14-30-24-5-1-3-19-4-2-6-25(26(19)24)33(30,31)32/h1-8,16-18,28H,9-15H2 XQGFTQNMDVGUBZ-UHFFFAOYSA-N 50047107 2-{2-[4-(5-Fluoro-1H-indol-2-ylmethyl)-piperidin-1-yl]-ethyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL19270 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646696 103977795 CHEMBL19270 ZINC28223845 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076312 CN1CCC(Cc2c[nH]c3ccc(F)cc23)CC1 InChI=1S/C15H19FN2/c1-18-6-4-11(5-7-18)8-12-10-17-15-3-2-13(16)9-14(12)15/h2-3,9-11,17H,4-8H2,1H3 XDSKCHPSIVKGHH-UHFFFAOYSA-N 50047101 5-Fluoro-3-(1-methyl-piperidin-4-ylmethyl)-1H-indole::CHEMBL414187 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047101&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646675 103977789 CHEMBL414187 ZINC13826858 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076314 CS(=O)(=O)N(CCN1CCC(Cc2c[nH]c3ccc(F)cc23)CC1)c1cccc2ccccc12 InChI=1S/C27H30FN3O2S/c1-34(32,33)31(27-8-4-6-21-5-2-3-7-24(21)27)16-15-30-13-11-20(12-14-30)17-22-19-29-26-10-9-23(28)18-25(22)26/h2-10,18-20,29H,11-17H2,1H3 FEIKDGZRYAUDTC-UHFFFAOYSA-N 50047104 CHEMBL19335::N-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-N-naphthalen-1-yl-methanesulfonamide D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047104&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646711 103977792 CHEMBL19335 ZINC13826849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076315 Fc1ccc2[nH]cc(C3=CCN(CCCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C26H24FN3O2S/c27-20-8-9-23-21(16-20)22(17-28-23)18-10-14-29(15-11-18)12-3-13-30-24-6-1-4-19-5-2-7-25(26(19)24)33(30,31)32/h1-2,4-10,16-17,28H,3,11-15H2 BWNZLYUMFNUWCY-UHFFFAOYSA-N 50047089 2-{3-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL18224 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047089&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646685 103977777 CHEMBL18224 ZINC13826825 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076318 Fc1ccc2c(CC3CCN(CCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c[nH]c2c1 InChI=1S/C26H26FN3O2S/c27-21-7-8-22-20(17-28-23(22)16-21)15-18-9-11-29(12-10-18)13-14-30-24-5-1-3-19-4-2-6-25(26(19)24)33(30,31)32/h1-8,16-18,28H,9-15H2 DREONVGEOAPMOI-UHFFFAOYSA-N 50047108 2-{2-[4-(6-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL19267 D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047108&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646693 103977796 CHEMBL19267 ZINC13826841 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076321 Fc1ccc2[nH]cc(CN3CCN(CCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C25H25FN4O2S/c26-20-7-8-22-21(15-20)19(16-27-22)17-29-11-9-28(10-12-29)13-14-30-23-5-1-3-18-4-2-6-24(25(18)23)33(30,31)32/h1-8,15-16,27H,9-14,17H2 VDYVPBAJQCJILV-UHFFFAOYSA-N 50047085 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperazin-1-yl]-ethyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL276922 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047085&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646695 103977773 CHEMBL276922 ZINC22940551 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076322 Fc1ccc2[nH]cc(CC3CCN(CCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C26H26FN3O2S/c27-21-7-8-23-22(16-21)20(17-28-23)15-18-9-11-29(12-10-18)13-14-30-24-5-1-3-19-4-2-6-25(26(19)24)33(30,31)32/h1-8,16-18,28H,9-15H2 AEXVRZSWDPHQBS-UHFFFAOYSA-N 50047100 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL18512 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047100&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646689 103977788 CHEMBL18512 ZINC00587497 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076335 Clc1ccc2[nH]cc(C3=CCN(CCCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C26H24ClN3O2S/c27-20-8-9-23-21(16-20)22(17-28-23)18-10-14-29(15-11-18)12-3-13-30-24-6-1-4-19-5-2-7-25(26(19)24)33(30,31)32/h1-2,4-10,16-17,28H,3,11-15H2 VZOLLFUDQJZBBU-UHFFFAOYSA-N 50047106 2-{3-[4-(5-Chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL429768 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047106&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646683 103977794 CHEMBL429768 ZINC13826821 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076337 CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1 InChI=1S/C17H18F3NO/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20/h2-10,16,21H,11-12H2,1H3 RTHCYVBBDHJXIQ-UHFFFAOYSA-N 30130 CHEMBL1201082::CHEMBL41::Fluoxetin::Fluoxetine::Prozac::US9120771, Fluoxetine::cid_62857 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30130&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search RFX 4MM8,3GWV 3386 85147891 5118 CHEMBL1201082CHEMBL41 DB00472 203 ZINC01530638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076349 Fc1ccc2[nH]cc(CC3CCN(CCn4c5cccc6CCCn(c56)c4=O)CC3)c2c1 InChI=1S/C26H29FN4O/c27-21-6-7-23-22(16-21)20(17-28-23)15-18-8-11-29(12-9-18)13-14-30-24-5-1-3-19-4-2-10-31(25(19)24)26(30)32/h1,3,5-7,16-18,28H,2,4,8-15H2 SEWRNPYYJIOWLZ-UHFFFAOYSA-N 50047092 1-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL19347 D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646710 103977780 CHEMBL19347 ZINC00587501 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076352 Brc1ccc2[nH]cc(C3=CCN(CCCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C26H24BrN3O2S/c27-20-8-9-23-21(16-20)22(17-28-23)18-10-14-29(15-11-18)12-3-13-30-24-6-1-4-19-5-2-7-25(26(19)24)33(30,31)32/h1-2,4-10,16-17,28H,3,11-15H2 QLRUMELLFYFLRX-UHFFFAOYSA-N 50047096 2-{3-[4-(5-Bromo-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL276565 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047096&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646684 103977784 CHEMBL276565 ZINC13826823 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076353 O=S1(=O)N(CCN2CCC(=CC2)c2c[nH]c3ccccc23)c2cccc3cccc1c23 InChI=1S/C25H23N3O2S/c29-31(30)24-10-4-6-19-5-3-9-23(25(19)24)28(31)16-15-27-13-11-18(12-14-27)21-17-26-22-8-2-1-7-20(21)22/h1-11,17,26H,12-16H2 ZSUPXNKHJARQNU-UHFFFAOYSA-N 50047097 2-{2-[4-(1H-Indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL274517 D(2) dopamine receptor Rattus norvegicus 81 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047097&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646686 103977785 CHEMBL274517 ZINC13826831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076357 O=S1(=O)N(CCCN2CCC(=CC2)c2c[nH]c3ccccc23)c2cccc3cccc1c23 InChI=1S/C26H25N3O2S/c30-32(31)25-11-4-7-20-6-3-10-24(26(20)25)29(32)15-5-14-28-16-12-19(13-17-28)22-18-27-23-9-2-1-8-21(22)23/h1-4,6-12,18,27H,5,13-17H2 ZAOJBQQNRCJZHT-UHFFFAOYSA-N 50047103 2-{3-[4-(1H-Indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL19613 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047103&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580039 103977791 CHEMBL19613 ZINC13826815 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076358 CN(CCN1CCC(Cc2c[nH]c3ccc(F)cc23)CC1)S(=O)(=O)c1ccc2ccccc2c1 InChI=1S/C27H30FN3O2S/c1-30(34(32,33)25-8-6-21-4-2-3-5-22(21)17-25)14-15-31-12-10-20(11-13-31)16-23-19-29-27-9-7-24(28)18-26(23)27/h2-9,17-20,29H,10-16H2,1H3 SLIUDVVBDVTWHY-UHFFFAOYSA-N 50047093 CHEMBL19228::Naphthalene-2-sulfonic acid {2-[4-(5-fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-ethyl}-methyl-amide D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646712 103977781 CHEMBL19228 ZINC13826851 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076361 Fc1ccc2[nH]cc(CC3CCN(CCCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C27H28FN3O2S/c28-22-8-9-24-23(17-22)21(18-29-24)16-19-10-14-30(15-11-19)12-3-13-31-25-6-1-4-20-5-2-7-26(27(20)25)34(31,32)33/h1-2,4-9,17-19,29H,3,10-16H2 XCHLEGMBTYTUAM-UHFFFAOYSA-N 50047109 2-{3-[4-(5-Fluoro-1H-indol-3-ylmethyl)-piperidin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL276920 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047109&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646690 103977797 CHEMBL276920 ZINC00587489 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076363 O=S1(=O)N(CCN2CCC(CC3=CCc4ccccc34)CC2)c2cccc3cccc1c23 InChI=1S/C27H28N2O2S/c30-32(31)26-10-4-7-22-6-3-9-25(27(22)26)29(32)18-17-28-15-13-20(14-16-28)19-23-12-11-21-5-1-2-8-24(21)23/h1-10,12,20H,11,13-19H2 LUENHUWMNYJIAU-UHFFFAOYSA-N 50047088 2-{2-[4-(3H-Inden-1-ylmethyl)-piperidin-1-yl]-ethyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL416544 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047088&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646697 103977776 CHEMBL416544 ZINC13826847 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076366 Fc1ccc2[nH]cc(CC3=CCN(CCN4c5cccc6cccc(c56)S4(=O)=O)CC3)c2c1 InChI=1S/C26H24FN3O2S/c27-21-7-8-23-22(16-21)20(17-28-23)15-18-9-11-29(12-10-18)13-14-30-24-5-1-3-19-4-2-6-25(26(19)24)33(30,31)32/h1-9,16-17,28H,10-15H2 DXRDZPVBTJXJJM-UHFFFAOYSA-N 50047091 2-{2-[4-(5-Fluoro-1H-indol-3-ylmethyl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL19051 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00061a010 10.7270/Q2MC8Z3Z 8487257 Malleron, JL; Gueremy, C; Mignani, S; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Laduron, P; Piot, O; Zundel, JL Centre de Recherches de Vitry-Alfortville http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047091&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646694 103977779 CHEMBL19051 ZINC13826843 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50075306 C(CN1C2CCC1c1c(C2)[nH]c2ccccc12)C(c1ccccc1)c1ccccc1 InChI=1S/C28H28N2/c1-3-9-20(10-4-1)23(21-11-5-2-6-12-21)17-18-30-22-15-16-27(30)28-24-13-7-8-14-25(24)29-26(28)19-22/h1-14,22-23,27,29H,15-19H2 ACYKYSGVGZMUIN-UHFFFAOYSA-N 50046454 15-(3,3-diphenylpropyl)-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL331611 D(2) dopamine receptor Rattus norvegicus 4520 ChEMBL 10.1021/jm00055a005 10.7270/Q21J98TX 8426363 Mewshaw, RE; Sherrill, RG; Mathew, RM; Kaiser, C; Bailey, MA; Karbon, EW Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046454&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149408 103977239 CHEMBL331611 ZINC27102677 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078557 CCCN(c1ccncc1)n1ccc2ccccc12 InChI=1S/C16H17N3/c1-2-12-18(15-7-10-17-11-8-15)19-13-9-14-5-3-4-6-16(14)19/h3-11,13H,2,12H2,1H3 OTPPJICEBWOCKD-UHFFFAOYSA-N 50048580 CHEMBL29835::Indol-1-yl-propyl-pyridin-4-yl-amine::Indol-1-yl-propyl-pyridin-4-yl-amine(Besipirdine) D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm9506433 10.7270/Q2BR8R7K 8558529 Klein, JT; Davis, L; Olsen, GE; Wong, GS; Huger, FP; Smith, CP; Petko, WW; Cornfeldt, M; Wilker, JC; Blitzer, RD; Landau, E; Haroutunian, V; Martin, LL; Effland, RC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048580&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60691 103978978 CHEMBL29835 ZINC00013715 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078898 O=c1[nH]c2ccc(CCN3CCN(CC3)c3nsc4ccccc34)cc2s1 InChI=1S/C20H20N4OS2/c25-20-21-16-6-5-14(13-18(16)26-20)7-8-23-9-11-24(12-10-23)19-15-3-1-2-4-17(15)27-22-19/h1-6,13H,7-12H2,(H,21,25) YNDNMVPWTKFLHF-UHFFFAOYSA-N 50048800 6-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-3H-benzothiazol-2-one::CHEMBL284847 D(2) dopamine receptor Rattus norvegicus 5.1 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620786 103979181 CHEMBL284847 ZINC13745236 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078900 Clc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21ClN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) MVWVFYHBGMAFLY-UHFFFAOYSA-N 50048803 5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one (Ziprasidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-chloro-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL708::GEODON::ZIPRASIDONE::ZIPRASIDONE HYDROCHLORIDE D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60854 103979184 10119 CHEMBL708 DB00246 59 C07568 ZINC00538550 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078902 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.71 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078906 O=C1Nc2ccc(CCN3CCN(CC3)c3nsc4ccccc34)cc2C11CCCC1 InChI=1S/C25H28N4OS/c30-24-25(10-3-4-11-25)20-17-18(7-8-21(20)26-24)9-12-28-13-15-29(16-14-28)23-19-5-1-2-6-22(19)31-27-23/h1-2,5-8,17H,3-4,9-16H2,(H,26,30) XWIUHFACKJAQHA-UHFFFAOYSA-N 50048802 5'-[2-(4-benzo[d]isothiazol-3-ylhexahydro-1-pyrazinyl)ethyl]spiro[cyclopentane-1,3'-(2',3'-dihydro-1'H-indole)]-2'-one::CHEMBL35565 D(2) dopamine receptor Rattus norvegicus 4.2 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10550699 103979183 CHEMBL35565 ZINC13745244 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078908 Fc1cc2NC(=O)Cc2cc1CCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H21FN4OS/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21/h1-4,11,13H,5-10,12H2,(H,23,27) UATKEUZQSUHYAC-UHFFFAOYSA-N 50048805 5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-fluoro-1,3-dihydro-indol-2-one::CHEMBL35040 D(2) dopamine receptor Rattus norvegicus 4.2 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692136 103979186 CHEMBL35040 ZINC29252118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078916 CC1(C)C(=O)Nc2ccc(CCN3CCN(CC3)c3nsc4ccccc34)cc12 InChI=1S/C23H26N4OS/c1-23(2)18-15-16(7-8-19(18)24-22(23)28)9-10-26-11-13-27(14-12-26)21-17-5-3-4-6-20(17)29-25-21/h3-8,15H,9-14H2,1-2H3,(H,24,28) XAQMBDNBRBOPIO-UHFFFAOYSA-N 50048807 5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-3,3-dimethyl-1,3-dihydro-indol-2-one::CHEMBL37633 D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669085 103979188 CHEMBL37633 ZINC13745242 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078919 O=c1[nH]c2ccc(CCN3CCN(CC3)c3nsc4ccccc34)cc2o1 InChI=1S/C20H20N4O2S/c25-20-21-16-6-5-14(13-17(16)26-20)7-8-23-9-11-24(12-10-23)19-15-3-1-2-4-18(15)27-22-19/h1-6,13H,7-12H2,(H,21,25) ZWSBCAMYZMCUFX-UHFFFAOYSA-N 50048801 6-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-3H-benzooxazol-2-one::CHEMBL35085 D(2) dopamine receptor Rattus norvegicus 6.3 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809803 103979182 CHEMBL35085 ZINC01484354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078921 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3.7 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078924 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2 ZFZPJDFBJFHYIV-UHFFFAOYSA-N 50007692 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL1204189::CHEMBL35057::TIOSPERONE D(2) dopamine receptor Rattus norvegicus 2.1 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55752 103920962 CHEMBL1204189CHEMBL35057 101 ZINC01915508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078925 O=C1Cc2cc(CCN3CCN(CC3)c3nsc4ccccc34)ccc2N1 InChI=1S/C21H22N4OS/c26-20-14-16-13-15(5-6-18(16)22-20)7-8-24-9-11-25(12-10-24)21-17-3-1-2-4-19(17)27-23-21/h1-6,13H,7-12,14H2,(H,22,26) LTKOVYPSNBPPDB-UHFFFAOYSA-N 50048804 5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-1,3-dihydro-indol-2-one::CHEMBL35743 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048804&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10150465 103979185 CHEMBL35743 ZINC13745234 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078927 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 83 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078931 CCN1C(=O)Cc2cc(CCN3CCN(CC3)c3nsc4ccccc34)ccc12 InChI=1S/C23H26N4OS/c1-2-27-20-8-7-17(15-18(20)16-22(27)28)9-10-25-11-13-26(14-12-25)23-19-5-3-4-6-21(19)29-24-23/h3-8,15H,2,9-14,16H2,1H3 UDHCGLWDZIOGOU-UHFFFAOYSA-N 50048806 5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-1-ethyl-1,3-dihydro-indol-2-one::CHEMBL287605 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm950625l 10.7270/Q2ZG6RB0 8568801 Howard, HR; Lowe, JA; Seeger, TF; Seymour, PA; Zorn, SH; Maloney, PR; Ewing, FE; Newman, ME; Schmidt, AW; Furman, JS; Robinson, GL; Jackson, E; Johnson, C; Morrone, J Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645038 103979187 CHEMBL287605 ZINC13745240 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078933 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078935 O=C1N(CC#CCN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 InChI=1S/C23H22N4OS/c28-23-19-8-2-1-7-18(19)17-27(23)12-6-5-11-25-13-15-26(16-14-25)22-20-9-3-4-10-21(20)29-24-22/h1-4,7-10H,11-17H2 FIYAPXAPOMZKIA-UHFFFAOYSA-N 50048810 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-but-2-ynyl]-2,3-dihydro-isoindol-1-one::CHEMBL559330 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10763646 103979191 CHEMBL559330 ZINC12356291 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078936 O=C1N(CCOCCN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 InChI=1S/C23H26N4O2S/c28-23-19-6-2-1-5-18(19)17-27(23)14-16-29-15-13-25-9-11-26(12-10-25)22-20-7-3-4-8-21(20)30-24-22/h1-8H,9-17H2 ABANXTFMSGCHMG-UHFFFAOYSA-N 50048809 2-{2-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethoxy]-ethyl}-2,3-dihydro-isoindol-1-one::CHEMBL288450 D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10764716 103979190 CHEMBL288450 ZINC12356360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078937 O=C1N(C\C=C/CN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C23H22N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h1-10H,11-16H2/b6-5- KYIHOKVBWAILAC-WAYWQWQTSA-N 50048811 2-[(Z)-4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-but-2-enyl]-isoindole-1,3-dione::CHEMBL43069 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645711 103979192 CHEMBL43069 ZINC13745258 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076881 Fc1ccc2c(CCCN3C4CCCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 InChI=1S/C24H23F2N3O/c25-14-7-9-19-18(11-14)24-21(27-19)13-16-3-1-5-22(24)29(16)10-2-4-20-17-8-6-15(26)12-23(17)30-28-20/h6-9,11-12,16,22,27H,1-5,10,13H2 SVUPKIFOEXQRAR-UHFFFAOYSA-N 50047437 1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-16-yl]propane::CHEMBL35096 D(2) dopamine receptor Rattus norvegicus 248 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047437&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646193 103978039 CHEMBL35096 ZINC13827356 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076882 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.470000 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076883 Fc1ccc(cc1)C(=O)CCCN1C2CCC1c1c(C2)n(-c2ccccc2)c2ccccc12 InChI=1S/C29H27FN2O/c30-21-14-12-20(13-15-21)28(33)11-6-18-31-23-16-17-26(31)29-24-9-4-5-10-25(24)32(27(29)19-23)22-7-2-1-3-8-22/h1-5,7-10,12-15,23,26H,6,11,16-19H2 BCQDBLPDCMUXPD-UHFFFAOYSA-N 50047435 1-(4-fluorophenyl)-4-[9-phenyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-butanone::CHEMBL37285 D(2) dopamine receptor Rattus norvegicus 840 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047435&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646157 103978037 CHEMBL37285 ZINC34616704 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076885 Fc1ccc2c(CCCN3C4CCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 InChI=1S/C23H21F2N3O/c24-13-4-7-18-17(10-13)23-20(26-18)12-15-5-8-21(23)28(15)9-1-2-19-16-6-3-14(25)11-22(16)29-27-19/h3-4,6-7,10-11,15,21,26H,1-2,5,8-9,12H2 FUWBTIWZNWXCRS-UHFFFAOYSA-N 50036651 (7R,10S)-1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::(7S,10R)-1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::CHEMBL284172 D(2) dopamine receptor Rattus norvegicus 308 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646187 103944292 CHEMBL284172 ZINC13827352 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076887 C(CN1C2CCC1c1c(C2)[nH]c2ccccc12)Cc1c[nH]c2ccccc12 InChI=1S/C24H25N3/c1-3-9-20-18(7-1)16(15-25-20)6-5-13-27-17-11-12-23(27)24-19-8-2-4-10-21(19)26-22(24)14-17/h1-4,7-10,15,17,23,25-26H,5-6,11-14H2 HVXBCBFOONESMF-UHFFFAOYSA-N 50047441 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-3-(1H-3-indolyl)propane::CHEMBL38309 D(2) dopamine receptor Rattus norvegicus 1155 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047441&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646182 103978043 CHEMBL38309 ZINC13827366 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076891 Fc1ccc2[nH]c3CC4CCC(N4CCCCC(=O)c4ccccc4)c3c2c1 InChI=1S/C24H25FN2O/c25-17-9-11-20-19(14-17)24-21(26-20)15-18-10-12-22(24)27(18)13-5-4-8-23(28)16-6-2-1-3-7-16/h1-3,6-7,9,11,14,18,22,26H,4-5,8,10,12-13,15H2 FOTLRAPJUJGUCI-UHFFFAOYSA-N 50047442 5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-phenyl-1-pentanone::CHEMBL37385 D(2) dopamine receptor Rattus norvegicus 2.8 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44284022 103978044 CHEMBL37385 ZINC29317746 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076892 Fc1ccc(CCCCN2C3CCC2c2c(C3)[nH]c3ccccc23)cc1 InChI=1S/C23H25FN2/c24-17-10-8-16(9-11-17)5-3-4-14-26-18-12-13-22(26)23-19-6-1-2-7-20(19)25-21(23)15-18/h1-2,6-11,18,22,25H,3-5,12-15H2 TYLIVIWKWHWCFT-UHFFFAOYSA-N 50046479 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(4-fluorophenyl)butane::CHEMBL38152 D(2) dopamine receptor Rattus norvegicus 1160 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646139 103977264 CHEMBL38152 ZINC13861330 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076893 Fc1ccc2[nH]c3CC4CCCC(N4CCCCc4ccccc4)c3c2c1 InChI=1S/C24H27FN2/c25-18-12-13-21-20(15-18)24-22(26-21)16-19-10-6-11-23(24)27(19)14-5-4-9-17-7-2-1-3-8-17/h1-3,7-8,12-13,15,19,23,26H,4-6,9-11,14,16H2 KYBUUIZCDMRELX-UHFFFAOYSA-N 50047443 1-[5-fluoro-9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-16-yl]-4-phenylbutane::CHEMBL284778 D(2) dopamine receptor Rattus norvegicus 1872 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646151 103978045 CHEMBL284778 ZINC13827330 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076894 Fc1ccc(cc1)C(=O)CCCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 InChI=1S/C24H24F2N2O/c25-16-6-4-15(5-7-16)23(29)3-1-2-12-28-18-9-11-22(28)24-19-13-17(26)8-10-20(19)27-21(24)14-18/h4-8,10,13,18,22,27H,1-3,9,11-12,14H2 VFPYMAAKRGRXBH-UHFFFAOYSA-N 50036650 (7R,10S)-5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::(7S,10R)-5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::CHEMBL291254 D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036650&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646166 103944291 CHEMBL291254 ZINC13827343 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076895 C(CCc1c[nH]c2ccccc12)CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C25H27N3/c1-3-10-21-19(8-1)17(16-26-21)7-5-6-14-28-18-12-13-24(28)25-20-9-2-4-11-22(20)27-23(25)15-18/h1-4,8-11,16,18,24,26-27H,5-7,12-15H2 XNMOWIHSJLFIBW-UHFFFAOYSA-N 50047444 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(1H-3-indolyl)butane::CHEMBL289722 D(2) dopamine receptor Rattus norvegicus 853 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646197 103978046 CHEMBL289722 ZINC13827368 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076897 C(CCc1ccccc1)CN1C2CCCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C24H28N2/c1-2-9-18(10-3-1)11-6-7-16-26-19-12-8-15-23(26)24-20-13-4-5-14-21(20)25-22(24)17-19/h1-5,9-10,13-14,19,23,25H,6-8,11-12,15-17H2 OPUKVGUEIVRYRA-UHFFFAOYSA-N 50047439 1-[9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-16-yl]-4-phenylbutane::CHEMBL285906 D(2) dopamine receptor Rattus norvegicus 670 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646147 103978041 CHEMBL285906 ZINC13827326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076899 Fc1ccc2[nH]c3CC4CCC(N4CCCCc4ccccc4)c3c2c1 InChI=1S/C23H25FN2/c24-17-9-11-20-19(14-17)23-21(25-20)15-18-10-12-22(23)26(18)13-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9,11,14,18,22,25H,4-5,8,10,12-13,15H2 SOTXRBRECFGWCR-UHFFFAOYSA-N 50046465 1-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-phenylbutane::CHEMBL35711 D(2) dopamine receptor Rattus norvegicus 769.0 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646141 103977250 CHEMBL35711 ZINC13827320 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076905 Fc1ccc(cc1)C(=O)CCCCN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C24H25FN2O/c25-17-10-8-16(9-11-17)23(28)7-3-4-14-27-18-12-13-22(27)24-19-5-1-2-6-20(19)26-21(24)15-18/h1-2,5-6,8-11,18,22,26H,3-4,7,12-15H2 AFVUFWHJUYVTQW-UHFFFAOYSA-N 50036647 (7R,10S)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::(7S,10R)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::CHEMBL285712 D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9842628 103944288 CHEMBL285712 ZINC03801105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078941 O=C1N(CCCCCN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 InChI=1S/C24H28N4OS/c29-24-20-9-3-2-8-19(20)18-28(24)13-7-1-6-12-26-14-16-27(17-15-26)23-21-10-4-5-11-22(21)30-25-23/h2-5,8-11H,1,6-7,12-18H2 DODCYUIQFWNTQY-UHFFFAOYSA-N 50048815 2-[5-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pentyl]-2,3-dihydro-isoindol-1-one::CHEMBL41636 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574164 103979196 CHEMBL41636 ZINC13745260 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078942 O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C23H24N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h1-4,7-10H,5-6,11-16H2 YKKGANFNJXSMSN-UHFFFAOYSA-N 50036918 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-isoindole-1,3-dione::CHEMBL290937 D(2) dopamine receptor Rattus norvegicus 49 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10093606 103944559 CHEMBL290937 ZINC02010593 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078943 O=C1N(C\C=C\CN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C23H22N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h1-10H,11-16H2/b6-5+ KYIHOKVBWAILAC-AATRIKPKSA-N 50048816 2-[(E)-4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-but-2-enyl]-isoindole-1,3-dione::CHEMBL290953 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025027 103979197 CHEMBL290953 ZINC13745256 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078945 O=C1N(CCCCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C25H28N4O2S/c30-24-19-9-3-4-10-20(19)25(31)29(24)14-8-2-1-7-13-27-15-17-28(18-16-27)23-21-11-5-6-12-22(21)32-26-23/h3-6,9-12H,1-2,7-8,13-18H2 ZWXUIJOENHRFLU-UHFFFAOYSA-N 50048817 2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-hexyl]-isoindole-1,3-dione::CHEMBL38409 D(2) dopamine receptor Rattus norvegicus 9.2 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286416 103979198 CHEMBL38409 ZINC29337316 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078946 O=C1N(CCCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C24H26N4O2S/c29-23-18-8-2-3-9-19(18)24(30)28(23)13-7-1-6-12-26-14-16-27(17-15-26)22-20-10-4-5-11-21(20)31-25-22/h2-5,8-11H,1,6-7,12-17H2 AGZPUSHGNOUMEV-UHFFFAOYSA-N 50048818 2-[5-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-pentyl]-isoindole-1,3-dione::CHEMBL41536 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717702 103979199 CHEMBL41536 ZINC13745250 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078947 O=C1N(CCOCCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C23H24N4O3S/c28-22-17-5-1-2-6-18(17)23(29)27(22)14-16-30-15-13-25-9-11-26(12-10-25)21-19-7-3-4-8-20(19)31-24-21/h1-8H,9-16H2 ZNQUBZLVCKKPOH-UHFFFAOYSA-N 50048819 2-{2-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethoxy]-ethyl}-isoindole-1,3-dione::CHEMBL38747 D(2) dopamine receptor Rattus norvegicus 170 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717788 103979200 CHEMBL38747 ZINC13745252 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078949 O=C1N(CCCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C22H22N4O2S/c27-21-16-6-1-2-7-17(16)22(28)26(21)11-5-10-24-12-14-25(15-13-24)20-18-8-3-4-9-19(18)29-23-20/h1-4,6-9H,5,10-15H2 UHYQVVJUEINPTK-UHFFFAOYSA-N 50048814 2-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-propyl]-isoindole-1,3-dione::CHEMBL39226 D(2) dopamine receptor Rattus norvegicus 340 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645029 103979195 CHEMBL39226 ZINC13745248 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078958 O=C1N(Cc2ccccc12)C1CCC(CC1)N1CCN(CC1)c1nsc2ccccc12 InChI=1S/C25H28N4OS/c30-25-21-6-2-1-5-18(21)17-29(25)20-11-9-19(10-12-20)27-13-15-28(16-14-27)24-22-7-3-4-8-23(22)31-26-24/h1-8,19-20H,9-17H2 SAUISYWTBAVIOY-UHFFFAOYSA-N 50048821 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-cyclohexyl]-2,3-dihydro-isoindol-1-one::CHEMBL41309 D(2) dopamine receptor Rattus norvegicus 7.6 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048821&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10550700 103979202 CHEMBL41309 ZINC12356423 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078959 O=C1N(CC#CCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C23H20N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h1-4,7-10H,11-16H2 LFDFDERYUSRWCV-UHFFFAOYSA-N 50048808 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-but-2-ynyl]-isoindole-1,3-dione::CHEMBL43513 D(2) dopamine receptor Rattus norvegicus 2800 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740625 103979189 CHEMBL43513 ZINC13745254 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078967 O=C1N(CCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C21H20N4O2S/c26-20-15-5-1-2-6-16(15)21(27)25(20)14-11-23-9-12-24(13-10-23)19-17-7-3-4-8-18(17)28-22-19/h1-8H,9-14H2 LTPDXYAZMVAPFX-UHFFFAOYSA-N 50048823 2-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-isoindole-1,3-dione::CHEMBL289275 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10786703 103979204 CHEMBL289275 ZINC13745246 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078970 O=C1N(CCN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 InChI=1S/C21H22N4OS/c26-21-17-6-2-1-5-16(17)15-25(21)14-11-23-9-12-24(13-10-23)20-18-7-3-4-8-19(18)27-22-20/h1-8H,9-15H2 UQLCGVMANUPFJO-UHFFFAOYSA-N 50048820 2-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-2,3-dihydro-isoindol-1-one::CHEMBL36423 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048820&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10833527 103979201 CHEMBL36423 ZINC12356213 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078977 O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 InChI=1S/C23H26N4OS/c28-23-19-8-2-1-7-18(19)17-27(23)12-6-5-11-25-13-15-26(16-14-25)22-20-9-3-4-10-21(20)29-24-22/h1-4,7-10H,5-6,11-17H2 ZPAUMFOJNAADJN-UHFFFAOYSA-N 50036922 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2,3-dihydro-isoindol-1-one::CHEMBL41626 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036922&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10046952 103944563 CHEMBL41626 ZINC01537574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078978 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 290 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078981 O=C1N(C\C=C/CN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 InChI=1S/C23H24N4OS/c28-23-19-8-2-1-7-18(19)17-27(23)12-6-5-11-25-13-15-26(16-14-25)22-20-9-3-4-10-21(20)29-24-22/h1-10H,11-17H2/b6-5- HDAOSJDKRACLFF-WAYWQWQTSA-N 50048812 2-[(Z)-4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-but-2-enyl]-2,3-dihydro-isoindol-1-one::CHEMBL43410 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048812&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795529 103979193 CHEMBL43410 ZINC13745267 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078983 O=C1N(CCCN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 InChI=1S/C22H24N4OS/c27-22-18-7-2-1-6-17(18)16-26(22)11-5-10-24-12-14-25(15-13-24)21-19-8-3-4-9-20(19)28-23-21/h1-4,6-9H,5,10-16H2 IXZQIGXIYXCIQZ-UHFFFAOYSA-N 50048822 2-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-propyl]-2,3-dihydro-isoindol-1-one::CHEMBL441430 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10786715 103979203 CHEMBL441430 ZINC12356255 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078987 O=C1N(CC2CC2CN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C24H24N4O2S/c29-23-18-5-1-2-6-19(18)24(30)28(23)15-17-13-16(17)14-26-9-11-27(12-10-26)22-20-7-3-4-8-21(20)31-25-22/h1-8,16-17H,9-15H2 UGMOAPLNQIPTAB-UHFFFAOYSA-N 50048813 2-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-ylmethyl)-cyclopropylmethyl]-isoindole-1,3-dione::CHEMBL288930 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286775 103979194 CHEMBL288930 ZINC12356421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50078991 O=C1N(C\C=C\CN2CCN(CC2)c2nsc3ccccc23)Cc2ccccc12 InChI=1S/C23H24N4OS/c28-23-19-8-2-1-7-18(19)17-27(23)12-6-5-11-25-13-15-26(16-14-25)22-20-9-3-4-10-21(20)29-24-22/h1-10H,11-17H2/b6-5+ HDAOSJDKRACLFF-AATRIKPKSA-N 50048824 2-[(E)-4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-but-2-enyl]-2,3-dihydro-isoindol-1-one::CHEMBL291070 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm9502201 10.7270/Q2TQ60MN 8568802 Norman, MH; Minick, DJ; Rigdon, GC Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048824&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795528 103979205 CHEMBL291070 ZINC13745265 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076908 C(CCc1cc2ccccc2s1)CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C25H26N2S/c1-4-11-24-17(7-1)15-19(28-24)8-5-6-14-27-18-12-13-23(27)25-20-9-2-3-10-21(20)26-22(25)16-18/h1-4,7,9-11,15,18,23,26H,5-6,8,12-14,16H2 NFZHTJRJDDMXHV-UHFFFAOYSA-N 50047448 1-benzo[b]thiophen-2-yl-4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::CHEMBL289563 D(2) dopamine receptor Rattus norvegicus 416.0 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047448&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283903 103978050 CHEMBL289563 ZINC13827364 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076909 Fc1ccc(cc1)C(=O)CCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 InChI=1S/C23H22F2N2O/c24-15-5-3-14(4-6-15)22(28)2-1-11-27-17-8-10-21(27)23-18-12-16(25)7-9-19(18)26-20(23)13-17/h3-7,9,12,17,21,26H,1-2,8,10-11,13H2 SWEUQJQJCWSLBM-UHFFFAOYSA-N 50036648 (7R,10S)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::(7S,10R)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::CHEMBL38151 D(2) dopamine receptor Rattus norvegicus 231.0 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646133 103944289 CHEMBL38151 ZINC13827314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076910 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 93 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076913 O=C(CCCN1C2CCC1c1c(C2)[nH]c2ccccc12)c1ccccc1 InChI=1S/C23H24N2O/c26-22(16-7-2-1-3-8-16)11-6-14-25-17-12-13-21(25)23-18-9-4-5-10-19(18)24-20(23)15-17/h1-5,7-10,17,21,24H,6,11-15H2 REORQBPIKFRAOM-UHFFFAOYSA-N 50047440 4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-phenyl-1-butanone::CHEMBL37010 D(2) dopamine receptor Rattus norvegicus 540 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646137 103978042 CHEMBL37010 ZINC12356167 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076914 Fc1ccc(CCCCN2C3CCCC2c2c(C3)[nH]c3ccccc23)cc1 InChI=1S/C24H27FN2/c25-18-13-11-17(12-14-18)6-3-4-15-27-19-7-5-10-23(27)24-20-8-1-2-9-21(20)26-22(24)16-19/h1-2,8-9,11-14,19,23,26H,3-7,10,15-16H2 HFDHTQNBCFVPGS-UHFFFAOYSA-N 50047450 1-[9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-16-yl]-4-(4-fluorophenyl)butane::CHEMBL36992 D(2) dopamine receptor Rattus norvegicus 973.0 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047450&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646149 103978052 CHEMBL36992 ZINC34616703 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076918 Fc1ccc(cc1)C(=O)CCCN1C2CCCC1c1c(C2)[nH]c2ccc(F)cc12 InChI=1S/C24H24F2N2O/c25-16-8-6-15(7-9-16)23(29)5-2-12-28-18-3-1-4-22(28)24-19-13-17(26)10-11-20(19)27-21(24)14-18/h6-11,13,18,22,27H,1-5,12,14H2 PRRYXSCMVWFRHJ-UHFFFAOYSA-N 50047446 4-{5-fluoro-9,16-diazatetracyclo[10.3.1.0^{2,10}.0^{3,8}]hexadeca-2(10),3,5,7-tetraen-16-yl}-1-(4-fluorophenyl)butan-1-one::CHEMBL37215 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646145 103978048 CHEMBL37215 ZINC13827324 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076921 O=C(CCCN1C2CCC1c1c(C2)[nH]c2ccccc12)c1cccs1 InChI=1S/C21H22N2OS/c24-19(20-8-4-12-25-20)7-3-11-23-14-9-10-18(23)21-15-5-1-2-6-16(15)22-17(21)13-14/h1-2,4-6,8,12,14,18,22H,3,7,9-11,13H2 GZLRSKHJKSOBOU-UHFFFAOYSA-N 50047452 4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(2-thienyl)-1-butanone::CHEMBL284928 D(2) dopamine receptor Rattus norvegicus 550 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047452&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646159 103978054 CHEMBL284928 ZINC36093043 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076922 Cn1c2CC3CCC(N3CCCC(=O)c3ccc(F)cc3)c2c2ccccc12 InChI=1S/C24H25FN2O/c1-26-20-6-3-2-5-19(20)24-21-13-12-18(15-22(24)26)27(21)14-4-7-23(28)16-8-10-17(25)11-9-16/h2-3,5-6,8-11,18,21H,4,7,12-15H2,1H3 NMLUMLDZLGGLOV-UHFFFAOYSA-N 50047445 1-(4-fluorophenyl)-4-[9-methyl-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-butanone::CHEMBL430551 D(2) dopamine receptor Rattus norvegicus 287.0 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646155 103978047 CHEMBL430551 ZINC29251533 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076926 Fc1ccc2[nH]c3CC4CCC(N4CCCCN4c5cccc6cccc(c56)S4(=O)=O)c3c2c1 InChI=1S/C27H26FN3O2S/c28-18-9-11-21-20(15-18)27-22(29-21)16-19-10-12-23(27)30(19)13-1-2-14-31-24-7-3-5-17-6-4-8-25(26(17)24)34(31,32)33/h3-9,11,15,19,23,29H,1-2,10,12-14,16H2 XHDKTJSMHZEKKN-UHFFFAOYSA-N 50047453 15-(4-2H-Naphtho[1,8-cd]isothiazole 1,1-dioxide)butyl-5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL36599 D(2) dopamine receptor Rattus norvegicus 1006 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646174 103978055 CHEMBL36599 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076927 O=C1N(CCCCN2C3CCC2c2c(C3)[nH]c3ccccc23)C(=O)c2ccccc12 InChI=1S/C25H25N3O2/c29-24-17-7-1-2-8-18(17)25(30)28(24)14-6-5-13-27-16-11-12-22(27)23-19-9-3-4-10-20(19)26-21(23)15-16/h1-4,7-10,16,22,26H,5-6,11-15H2 ZFVCOZSVRXMIIP-UHFFFAOYSA-N 50047451 2-{4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butyl}-1,3-isoindolinedione::CHEMBL37717 D(2) dopamine receptor Rattus norvegicus 2630 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047451&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646176 103978053 CHEMBL37717 ZINC36093045 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076928 Fc1ccc2c(CCCCN3C4CCCC3c3c(C4)[nH]c4cccc(F)c34)noc2c1 InChI=1S/C25H25F2N3O/c26-15-10-11-17-19(29-31-23(17)13-15)7-1-2-12-30-16-5-3-9-22(30)25-21(14-16)28-20-8-4-6-18(27)24(20)25/h4,6,8,10-11,13,16,22,28H,1-3,5,7,9,12,14H2 RVCVITJTEQPETF-UHFFFAOYSA-N 50047454 1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[4-fluoro-9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-16-yl]butane::CHEMBL418607 D(2) dopamine receptor Rattus norvegicus 131 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047454&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283959 103978056 CHEMBL418607 ZINC36093044 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076929 Fc1ccc2c(CCCCN3C4CCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 InChI=1S/C24H23F2N3O/c25-14-5-8-19-18(11-14)24-21(27-19)13-16-6-9-22(24)29(16)10-2-1-3-20-17-7-4-15(26)12-23(17)30-28-20/h4-5,7-8,11-12,16,22,27H,1-3,6,9-10,13H2 RKKLLFDATFBVDR-UHFFFAOYSA-N 50036649 (7R,10S)-1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::(7S,10R)-1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::CHEMBL284163 D(2) dopamine receptor Rattus norvegicus 2.7 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646191 103944290 CHEMBL284163 ZINC13827354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076936 C1CC2NC1Cc1[nH]c3ccccc3c21 InChI=1S/C13H14N2/c1-2-4-10-9(3-1)13-11-6-5-8(14-11)7-12(13)15-10/h1-4,8,11,14-15H,5-7H2 ZUBTZRPXJLZWKF-UHFFFAOYSA-N 50046468 9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraene::CHEMBL285541 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149426 103977253 CHEMBL285541 ZINC29306978 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076937 Fc1ccc(CCCCN2C3CCCC2c2c(C3)[nH]c3ccc(F)cc23)cc1 InChI=1S/C24H26F2N2/c25-17-9-7-16(8-10-17)4-1-2-13-28-19-5-3-6-23(28)24-20-14-18(26)11-12-21(20)27-22(24)15-19/h7-12,14,19,23,27H,1-6,13,15H2 HFQNYAGAZJZTFL-UHFFFAOYSA-N 50047447 1-[5-fluoro-9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-16-yl]-4-(4-fluorophenyl)butane::CHEMBL34958 D(2) dopamine receptor Rattus norvegicus 1965 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646153 103978049 CHEMBL34958 ZINC13827332 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076938 C(CCc1ccccc1)CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C23H26N2/c1-2-8-17(9-3-1)10-6-7-15-25-18-13-14-22(25)23-19-11-4-5-12-20(19)24-21(23)16-18/h1-5,8-9,11-12,18,22,24H,6-7,10,13-16H2 YJWKPDMZHMZMRC-UHFFFAOYSA-N 50046482 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-phenylbutane::CHEMBL38130 D(2) dopamine receptor Rattus norvegicus 735 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046482&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646135 103977267 CHEMBL38130 ZINC13827316 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076939 Fc1ccc(cc1)C(=O)CCCN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C23H23FN2O/c24-16-9-7-15(8-10-16)22(27)6-3-13-26-17-11-12-21(26)23-18-4-1-2-5-19(18)25-20(23)14-17/h1-2,4-5,7-10,17,21,25H,3,6,11-14H2 CEDSKJUGADVONS-UHFFFAOYSA-N 50046475 4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-butanone::CHEMBL36645 D(2) dopamine receptor Rattus norvegicus 275 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046475&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15149406 103977260 CHEMBL36645 ZINC13827312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076941 Fc1ccc(cc1)C(=O)CCCN1C2CCCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C24H25FN2O/c25-17-12-10-16(11-13-17)23(28)9-4-14-27-18-5-3-8-22(27)24-19-6-1-2-7-20(19)26-21(24)15-18/h1-2,6-7,10-13,18,22,26H,3-5,8-9,14-15H2 CBYRMSTXGLKWPL-UHFFFAOYSA-N 50047457 4-[9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-16-yl]-1-(4-fluorophenyl)-1-butanone::CHEMBL38078 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646143 103978059 CHEMBL38078 ZINC34616702 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076943 O=C1CC2(CCCC2)CC(=O)N1CCCCN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C26H33N3O2/c30-23-16-26(11-3-4-12-26)17-24(31)29(23)14-6-5-13-28-18-9-10-22(28)25-19-7-1-2-8-20(19)27-21(25)15-18/h1-2,7-8,18,22,27H,3-6,9-17H2 JAKRKKAOZPPTDH-UHFFFAOYSA-N 50046473 8-{4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione::CHEMBL285203 D(2) dopamine receptor Rattus norvegicus 3007 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50046473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50046473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646180 103977258 CHEMBL285203 ZINC13861334 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076944 C(CCn1ccc2ccccc12)CN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C25H27N3/c1-4-10-23-18(7-1)13-16-27(23)14-5-6-15-28-19-11-12-24(28)25-20-8-2-3-9-21(20)26-22(25)17-19/h1-4,7-10,13,16,19,24,26H,5-6,11-12,14-15,17H2 RLKBETCYPSXCSX-UHFFFAOYSA-N 50047455 1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-4-(1H-1-indolyl)butane::CHEMBL37483 D(2) dopamine receptor Rattus norvegicus 635 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047455&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646178 103978057 CHEMBL37483 ZINC13827362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076946 Fc1ccc(cc1)C(=O)CCCN1C2CCC1CC(=O)C2 InChI=1S/C17H20FNO2/c18-13-5-3-12(4-6-13)17(21)2-1-9-19-14-7-8-15(19)11-16(20)10-14/h3-6,14-15H,1-2,7-11H2 JSYYJKRFHUQKLJ-UHFFFAOYSA-N 50047436 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-8-aza-bicyclo[3.2.1]octan-3-one::CHEMBL35536 D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13091267 103978038 CHEMBL35536 ZINC29252424 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076948 Fc1ccc2[nH]c3CC4CCC(N4CCCC(=O)c4ccco4)c3c2c1 InChI=1S/C21H21FN2O2/c22-13-5-7-16-15(11-13)21-17(23-16)12-14-6-8-18(21)24(14)9-1-3-19(25)20-4-2-10-26-20/h2,4-5,7,10-11,14,18,23H,1,3,6,8-9,12H2 HMWCSFUVGFNRSK-UHFFFAOYSA-N 50047456 4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(2-furyl)-1-butanone::CHEMBL37131 D(2) dopamine receptor Rattus norvegicus 643.0 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646199 103978058 CHEMBL37131 ZINC13827338 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076949 Fc1ccc2[nH]c3CC4CCCC(N4CCCCC(=O)c4ccccc4)c3c2c1 InChI=1S/C25H27FN2O/c26-18-12-13-21-20(15-18)25-22(27-21)16-19-9-6-10-23(25)28(19)14-5-4-11-24(29)17-7-2-1-3-8-17/h1-3,7-8,12-13,15,19,23,27H,4-6,9-11,14,16H2 ZBZUALDDFSORLV-UHFFFAOYSA-N 50047438 5-[5-fluoro-9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-16-yl]-1-phenyl-1-pentanone::CHEMBL38337 D(2) dopamine receptor Rattus norvegicus 72 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283877 103978040 CHEMBL38337 ZINC29307109 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50076950 O=C(CCCCN1C2CCCC1c1c(C2)[nH]c2ccccc12)c1ccccc1 InChI=1S/C25H28N2O/c28-24(18-9-2-1-3-10-18)15-6-7-16-27-19-11-8-14-23(27)25-20-12-4-5-13-21(20)26-22(25)17-19/h1-5,9-10,12-13,19,23,26H,6-8,11,14-17H2 YRSRTQZYVZWNKO-UHFFFAOYSA-N 50047449 5-[9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca-2(10),3,5,7-tetraen-16-yl]-1-phenyl-1-pentanone::CHEMBL285030 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm00062a023 10.7270/Q2KD1X0K 8496917 Mewshaw, RE; Silverman, LS; Mathew, RM; Kaiser, C; Sherrill, RG; Cheng, M; Tiffany, CW; Karbon, EW; Bailey, MA; Borosky, SA Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047449&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44284008 103978051 CHEMBL285030 ZINC29319134 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032389 CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)ccc1OC InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 CANPFCFJURGKAX-JTQLQIEISA-N 50012961 (-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::CHEMBL267723::N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide (IBZM)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide( (S)-(-)IBZM) D(2) dopamine receptor Rattus norvegicus 0.261000 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 107995 103925209 CHEMBL267723 ZINC03786360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032390 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc2CCOc12 InChI=1S/C16H21IN2O2/c1-2-19-6-3-4-13(19)10-18-16(20)14-9-12(17)8-11-5-7-21-15(11)14/h8-9,13H,2-7,10H2,1H3,(H,18,20)/t13-/m0/s1 SXAMDWYVBFWJLU-ZDUSSCGKSA-N 50012965 5-Iodo-2,3-dihydro-benzofuran-7-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide ((S)-(-)IBF)::5-Iodo-2,3-dihydro-benzofuran-7-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide (IBF)::CHEMBL48450 D(2) dopamine receptor Rattus norvegicus 0.230000 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012965&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3035942 103925213 CHEMBL48450 ZINC03784279 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50083019 COc1ccc(C)cc1N1CCN(CCCNc2cc(=O)n(C)c(=O)n2C)CC1 InChI=1S/C21H31N5O3/c1-16-6-7-18(29-4)17(14-16)26-12-10-25(11-13-26)9-5-8-22-19-15-20(27)24(3)21(28)23(19)2/h6-7,14-15,22H,5,8-13H2,1-4H3 RAWLZBUZFGOUJJ-UHFFFAOYSA-N 50050916 6-{3-[4-(2-Methoxy-5-methyl-phenyl)-piperazin-1-yl]-propylamino}-1,3-dimethyl-1H-pyrimidine-2,4-dione::CHEMBL76168 D(2) dopamine receptor Rattus norvegicus 935.1 ChEMBL 10.1021/jm960069a 10.7270/Q22Z14NF 8667368 Quaglia, W; Pigini, M; Tayebati, SK; Piergentili, A; Giannella, M; Leonardi, A; Taddei, C; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050916&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312563 103948009 CHEMBL76168 ZINC26382583 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50083024 COc1cccc(OC)c1OCCNC[C@@H]1Oc2ccccc2O[C@H]1c1ccc(C)cc1 InChI=1S/C26H29NO5/c1-18-11-13-19(14-12-18)25-24(31-20-7-4-5-8-21(20)32-25)17-27-15-16-30-26-22(28-2)9-6-10-23(26)29-3/h4-14,24-25,27H,15-17H2,1-3H3/t24-,25-/m0/s1 UNHGFWKSHHCRHF-DQEYMECFSA-N 50050915 CHEMBL72657::[2-(2,6-Dimethoxy-phenoxy)-ethyl]-((2S,3S)-3-p-tolyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-amine D(2) dopamine receptor Rattus norvegicus 86.48 ChEMBL 10.1021/jm960069a 10.7270/Q22Z14NF 8667368 Quaglia, W; Pigini, M; Tayebati, SK; Piergentili, A; Giannella, M; Leonardi, A; Taddei, C; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050915&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599007 103948008 CHEMBL72657 ZINC13473094 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50083027 COc1cccc(OC)c1OCCNCC1Oc2ccccc2OC1c1ccc(C)cc1 InChI=1S/C26H29NO5/c1-18-11-13-19(14-12-18)25-24(31-20-7-4-5-8-21(20)32-25)17-27-15-16-30-26-22(28-2)9-6-10-23(26)29-3/h4-14,24-25,27H,15-17H2,1-3H3 UNHGFWKSHHCRHF-UHFFFAOYSA-N 50050917 CHEMBL42539::[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(3-p-tolyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-amine D(2) dopamine receptor Rattus norvegicus 82.34 ChEMBL 10.1021/jm960069a 10.7270/Q22Z14NF 8667368 Quaglia, W; Pigini, M; Tayebati, SK; Piergentili, A; Giannella, M; Leonardi, A; Taddei, C; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44289525 103948010 CHEMBL42539 ZINC13756315 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50083044 COc1cccc(OC)c1OCCNC[C@H]1Oc2ccccc2O[C@@H]1c1ccc(C)cc1 InChI=1S/C26H29NO5/c1-18-11-13-19(14-12-18)25-24(31-20-7-4-5-8-21(20)32-25)17-27-15-16-30-26-22(28-2)9-6-10-23(26)29-3/h4-14,24-25,27H,15-17H2,1-3H3/t24-,25-/m1/s1 UNHGFWKSHHCRHF-JWQCQUIFSA-N 50050913 CHEMBL286565::[2-(2,6-Dimethoxy-phenoxy)-ethyl]-((2R,3R)-3-p-tolyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-amine::[2-(2,6-Dimethoxy-phenoxy)-ethyl]-(3-p-tolyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-amine D(2) dopamine receptor Rattus norvegicus 827.3 ChEMBL 10.1021/jm960069a 10.7270/Q22Z14NF 8667368 Quaglia, W; Pigini, M; Tayebati, SK; Piergentili, A; Giannella, M; Leonardi, A; Taddei, C; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50050913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50050913&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10320782 103948006 CHEMBL286565 ZINC13756313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50083049 COc1cccc(OC)c1OCCNCC1COc2ccccc2O1 InChI=1S/C19H23NO5/c1-21-17-8-5-9-18(22-2)19(17)23-11-10-20-12-14-13-24-15-6-3-4-7-16(15)25-14/h3-9,14,20H,10-13H2,1-2H3 GYSZUJHYXCZAKI-UHFFFAOYSA-N 69602 2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride::CHEMBL25554::MLS000859914::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride::SMR000326775::WB-4101::WB-4101 hydrochloride::cid_11957505 D(2) dopamine receptor Rattus norvegicus 122.8 ChEMBL 10.1021/jm960069a 10.7270/Q22Z14NF 8667368 Quaglia, W; Pigini, M; Tayebati, SK; Piergentili, A; Giannella, M; Leonardi, A; Taddei, C; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5685 252647768 64094 CHEMBL25554 ZINC02169424 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085524 Cc1ccc(cc1)S([O-])(=O)=O.CN1CCN2[C@H]3CC[NH+](CCCC(=O)c4ccc(F)cc4)C[C@H]3c3cccc1c23 InChI=1S/C24H28FN3O.C7H8O3S/c1-26-14-15-28-21-11-13-27(16-20(21)19-4-2-5-22(26)24(19)28)12-3-6-23(29)17-7-9-18(25)10-8-17;1-6-2-4-7(5-3-6)11(8,9)10/h2,4-5,7-10,20-21H,3,6,11-16H2,1H3;2-5H,1H3,(H,8,9,10)/t20-,21-;/m0./s1 LHAPOGAFBLSJJQ-GUTACTQSSA-N 50007659 CHEMBL3233142 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007659&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655111 103920929 CHEMBL3233142 ZINC13824832 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085525 Fc1ccc(cc1)C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3NCCN2c13 InChI=1S/C23H26FN3O/c24-17-8-6-16(7-9-17)22(28)5-2-12-26-13-10-21-19(15-26)18-3-1-4-20-23(18)27(21)14-11-25-20/h1,3-4,6-9,19,21,25H,2,5,10-15H2/t19-,21-/m0/s1 WPJSNLWFVMFFSG-FPOVZHCZSA-N 50007667 CHEMBL3233143 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007667&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302486 103920937 CHEMBL3233143 ZINC13824809 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085527 CCN1CCN2[C@H]3CCN(CCCC(=O)c4ccc(F)cc4)C[C@H]3c3cccc1c23 InChI=1S/C25H30FN3O/c1-2-28-15-16-29-22-12-14-27(17-21(22)20-5-3-6-23(28)25(20)29)13-4-7-24(30)18-8-10-19(26)11-9-18/h3,5-6,8-11,21-22H,2,4,7,12-17H2,1H3/t21-,22-/m0/s1 FGLHWNAUXDJDRA-VXKWHMMOSA-N 50007668 CHEMBL3233144 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007668&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302488 103920938 CHEMBL3233144 ZINC13824767 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085528 Fc1ccc(cc1)C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3N(Cc4ccccc4)CCN2c13 InChI=1S/C30H32FN3O/c31-24-13-11-23(12-14-24)29(35)10-5-16-32-17-15-27-26(21-32)25-8-4-9-28-30(25)34(27)19-18-33(28)20-22-6-2-1-3-7-22/h1-4,6-9,11-14,26-27H,5,10,15-21H2/t26-,27-/m0/s1 RLXPBWGKEXGWMJ-SVBPBHIXSA-N 50007671 CHEMBL3233147 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007671&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302487 103920941 CHEMBL3233147 ZINC13824881 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085529 COc1cc2[C@@H]3CN(CCCC(=O)c4ccc(F)cc4)CC[C@@H]3N3CCN(C)c(c1)c23 InChI=1S/C25H30FN3O2/c1-27-12-13-29-22-9-11-28(10-3-4-24(30)17-5-7-18(26)8-6-17)16-21(22)20-14-19(31-2)15-23(27)25(20)29/h5-8,14-15,21-22H,3-4,9-13,16H2,1-2H3/t21-,22-/m0/s1 ODXIOKASJQTTEX-VXKWHMMOSA-N 50007673 CHEMBL3233149 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007673&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10310067 103920943 CHEMBL3233149 ZINC13825271 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085534 CN1CCN2[C@H]3CCN(CCCC(=O)c4ccccc4)C[C@H]3c3cccc1c23 InChI=1S/C24H29N3O/c1-25-15-16-27-21-12-14-26(13-6-11-23(28)18-7-3-2-4-8-18)17-20(21)19-9-5-10-22(25)24(19)27/h2-5,7-10,20-21H,6,11-17H2,1H3/t20-,21-/m0/s1 KIOLUKGHLOUGFU-SFTDATJTSA-N 50007675 CHEMBL3233406 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007675&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655115 103920945 CHEMBL3233406 ZINC13825275 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085536 CN1CCN2[C@H]3CCN(CCCC(=O)c4ccncc4)C[C@H]3c3cccc1c23 InChI=1S/C23H28N4O/c1-25-14-15-27-20-9-13-26(12-3-6-22(28)17-7-10-24-11-8-17)16-19(20)18-4-2-5-21(25)23(18)27/h2,4-5,7-8,10-11,19-20H,3,6,9,12-16H2,1H3/t19-,20-/m0/s1 GCOQAARUFVDXHC-PMACEKPBSA-N 50007678 CHEMBL3233407 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007678&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10216348 103920948 CHEMBL3233407 ZINC13825269 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085538 CN1CCN2[C@H]3CCN(CCCC(=O)N4CCC(F)(F)CC4)C[C@H]3c3cccc1c23 InChI=1S/C23H32F2N4O/c1-26-14-15-29-19-7-11-27(16-18(19)17-4-2-5-20(26)22(17)29)10-3-6-21(30)28-12-8-23(24,25)9-13-28/h2,4-5,18-19H,3,6-16H2,1H3/t18-,19-/m0/s1 YNYJUMPPJZXNLG-OALUTQOASA-N 50007679 CHEMBL3233408 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655116 103920949 CHEMBL3233408 ZINC13825279 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085539 CN1CCN2[C@H]3CCN(CCCOc4ccc(F)cc4)C[C@H]3c3cccc1c23 InChI=1S/C23H28FN3O/c1-25-13-14-27-21-10-12-26(11-3-15-28-18-8-6-17(24)7-9-18)16-20(21)19-4-2-5-22(25)23(19)27/h2,4-9,20-21H,3,10-16H2,1H3/t20-,21-/m0/s1 HQQJXCPFCHRCKP-SFTDATJTSA-N 50007680 CHEMBL3233409 D(2) dopamine receptor Rattus norvegicus 213 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21302505 103920950 CHEMBL3233409 ZINC13825281 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085541 CN1CCN2[C@H]3CCN(CCNC(=O)c4ccc(F)cc4)C[C@H]3c3cccc1c23 InChI=1S/C23H27FN4O/c1-26-13-14-28-20-9-11-27(15-19(20)18-3-2-4-21(26)22(18)28)12-10-25-23(29)16-5-7-17(24)8-6-16/h2-8,19-20H,9-15H2,1H3,(H,25,29)/t19-,20-/m0/s1 LYOXRYZFGVMNBM-PMACEKPBSA-N 50007681 CHEMBL3233410 D(2) dopamine receptor Rattus norvegicus 767 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007681&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655117 103920951 CHEMBL3233410 ZINC03312239 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085542 CN1CCN2[C@H]3CCN(CCCc4noc5ccccc45)C[C@H]3c3cccc1c23 InChI=1S/C24H28N4O/c1-26-14-15-28-21-11-13-27(16-19(21)17-7-4-9-22(26)24(17)28)12-5-8-20-18-6-2-3-10-23(18)29-25-20/h2-4,6-7,9-10,19,21H,5,8,11-16H2,1H3/t19-,21-/m0/s1 FINYFOYZAZLCFE-FPOVZHCZSA-N 50007682 CHEMBL3233411 D(2) dopamine receptor Rattus norvegicus 174 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007682&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10287924 103920952 CHEMBL3233411 ZINC13825285 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085545 CN1CCN2[C@H]3CCN(CCCc4noc5cc(F)ccc45)C[C@H]3c3cccc1c23 InChI=1S/C24H27FN4O/c1-27-12-13-29-21-9-11-28(15-19(21)17-4-2-6-22(27)24(17)29)10-3-5-20-18-8-7-16(25)14-23(18)30-26-20/h2,4,6-8,14,19,21H,3,5,9-13,15H2,1H3/t19-,21-/m0/s1 ZJYUQATUAGWNGI-FPOVZHCZSA-N 50007683 CHEMBL3233412 D(2) dopamine receptor Rattus norvegicus 192 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007683&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10151426 103920953 CHEMBL3233412 ZINC13825273 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085546 CN1CCN2[C@H]3CCN(CCCc4n[nH]c5cc(F)ccc45)C[C@H]3c3cccc1c23 InChI=1S/C24H28FN5/c1-28-12-13-30-22-9-11-29(15-19(22)17-4-2-6-23(28)24(17)30)10-3-5-20-18-8-7-16(25)14-21(18)27-26-20/h2,4,6-8,14,19,22H,3,5,9-13,15H2,1H3,(H,26,27)/t19-,22-/m0/s1 RSNYLBGZLKEOAP-UGKGYDQZSA-N 50007684 CHEMBL3233413 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655118 103920954 CHEMBL3233413 ZINC13742670 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085547 CN1CCN2[C@H]3CCN(CCc4cc5CC(=O)Nc5cc4Cl)C[C@H]3c3cccc1c23 InChI=1S/C24H27ClN4O/c1-27-9-10-29-21-6-8-28(14-18(21)17-3-2-4-22(27)24(17)29)7-5-15-11-16-12-23(30)26-20(16)13-19(15)25/h2-4,11,13,18,21H,5-10,12,14H2,1H3,(H,26,30)/t18-,21-/m0/s1 OTDPJMWYRGSJQU-RXVVDRJESA-N 50007686 CHEMBL3233415 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655120 103920956 CHEMBL3233415 ZINC13825289 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085548 CN1CCN2[C@H]3CCN(CCc4c(C)nc5cc(C)ccn5c4=O)C[C@H]3c3cccc1c23 InChI=1S/C26H31N5O/c1-17-7-12-31-24(15-17)27-18(2)19(26(31)32)8-10-29-11-9-22-21(16-29)20-5-4-6-23-25(20)30(22)14-13-28(23)3/h4-7,12,15,21-22H,8-11,13-14,16H2,1-3H3/t21-,22-/m0/s1 MDKGKTITVZUGQM-VXKWHMMOSA-N 50007687 CHEMBL3233416 D(2) dopamine receptor Rattus norvegicus 3000 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007687&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655121 103920957 CHEMBL3233416 ZINC22937653 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085549 CN1CCN2[C@H]3CCN(CCCCN4C(=O)[C@H]5CCCC[C@H]5C4=O)C[C@H]3c3cccc1c23 InChI=1S/C26H36N4O2/c1-27-15-16-29-22-11-14-28(17-21(22)18-9-6-10-23(27)24(18)29)12-4-5-13-30-25(31)19-7-2-3-8-20(19)26(30)32/h6,9-10,19-22H,2-5,7-8,11-17H2,1H3/t19-,20+,21-,22-/m0/s1 SAVMLHSMVPTFGK-LRSLUSHPSA-N 50007708 CHEMBL3233417 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007708&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655122 103920978 CHEMBL3233417 ZINC27887730 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085551 CN1CCN2[C@H]3CCN(CCCN4C(=O)[C@H]5CCCC[C@H]5C4=O)C[C@H]3c3cccc1c23 InChI=1S/C25H34N4O2/c1-26-14-15-28-21-10-13-27(16-20(21)17-8-4-9-22(26)23(17)28)11-5-12-29-24(30)18-6-2-3-7-19(18)25(29)31/h4,8-9,18-21H,2-3,5-7,10-16H2,1H3/t18-,19+,20-,21-/m0/s1 VDIYIRDGLOQARY-WOZUAGRISA-N 50007709 CHEMBL3233418 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007709&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655123 103920979 CHEMBL3233418 ZINC27883764 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085552 CN1CCN2[C@@H]3CCN(CCCC(=O)c4ccc(F)cc4)C[C@@H]3c3cccc1c23 InChI=1S/C24H28FN3O/c1-26-14-15-28-21-11-13-27(16-20(21)19-4-2-5-22(26)24(19)28)12-3-6-23(29)17-7-9-18(25)10-8-17/h2,4-5,7-10,20-21H,3,6,11-16H2,1H3/t20-,21-/m1/s1 HOIIHACBCFLJET-NHCUHLMSSA-N 50007710 CHEMBL3233419 D(2) dopamine receptor Rattus norvegicus 95 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007710&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 69471377 103920980 CHEMBL3233419 ZINC27893111 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085553 CN1CCN2[C@H]3CCN(CCCC(=O)c4ccc(F)cc4)C[C@@H]3c3cccc1c23 InChI=1S/C24H28FN3O/c1-26-14-15-28-21-11-13-27(16-20(21)19-4-2-5-22(26)24(19)28)12-3-6-23(29)17-7-9-18(25)10-8-17/h2,4-5,7-10,20-21H,3,6,11-16H2,1H3/t20-,21+/m1/s1 HOIIHACBCFLJET-RTWAWAEBSA-N 50007711 CHEMBL3233420 D(2) dopamine receptor Rattus norvegicus 97 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007711&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655124 103920981 CHEMBL3233420 ZINC27885802 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085554 CN1CCN2[C@@H]3CCN(CCCC(=O)c4ccc(F)cc4)C[C@H]3c3cccc1c23 InChI=1S/C24H28FN3O/c1-26-14-15-28-21-11-13-27(16-20(21)19-4-2-5-22(26)24(19)28)12-3-6-23(29)17-7-9-18(25)10-8-17/h2,4-5,7-10,20-21H,3,6,11-16H2,1H3/t20-,21+/m0/s1 HOIIHACBCFLJET-LEWJYISDSA-N 50007712 CHEMBL3233421 D(2) dopamine receptor Rattus norvegicus 52 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007712&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655125 103920982 CHEMBL3233421 ZINC27889873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085570 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088029 CCN(CCOc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12)CCN1CCNC1=O InChI=1S/C23H26ClFN4O2/c1-2-27(11-12-28-10-9-26-23(28)30)13-14-31-22-16-29(19-6-4-18(25)5-7-19)21-8-3-17(24)15-20(21)22/h3-8,15-16H,2,9-14H2,1H3,(H,26,30) RXCYMHUQTXMXGO-UHFFFAOYSA-N 50053201 1-[2-({2-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yloxy]-ethyl}-ethyl-amino)-ethyl]-imidazolidin-2-one::CHEMBL421239 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053201&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10503470 103949915 CHEMBL421239 ZINC13758607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088031 CN(C)CCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C18H18ClFN2/c1-21(2)10-9-13-12-22(16-6-4-15(20)5-7-16)18-8-3-14(19)11-17(13)18/h3-8,11-12H,9-10H2,1-2H3 WZXHSSNOEBHYEF-UHFFFAOYSA-N 50053204 CHEMBL332365::{2-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053204&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10734233 103949918 CHEMBL332365 ZINC13758589 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088032 CN(CCOc1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12)CCN1CCNC1=O InChI=1S/C22H24ClFN4O2/c1-26(10-11-27-9-8-25-22(27)29)12-13-30-21-15-28(18-5-3-17(24)4-6-18)20-14-16(23)2-7-19(20)21/h2-7,14-15H,8-13H2,1H3,(H,25,29) DWVWCCIVOJGTTI-UHFFFAOYSA-N 50053190 1-[2-({2-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yloxy]-ethyl}-methyl-amino)-ethyl]-imidazolidin-2-one::CHEMBL333774 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053190&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10550615 103949904 CHEMBL333774 ZINC13758617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088037 CN(C)Cc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C17H16ClFN2/c1-20(2)10-12-11-21(15-6-4-14(19)5-7-15)17-8-3-13(18)9-16(12)17/h3-9,11H,10H2,1-2H3 SPLFGEFBTYQRPO-UHFFFAOYSA-N 50053194 CHEMBL301956::[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylmethyl]-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053194&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10518508 103949908 CHEMBL301956 ZINC13489973 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088040 CN(C)CCc1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 InChI=1S/C18H18ClFN2/c1-21(2)10-9-13-12-22(16-6-4-15(20)5-7-16)18-11-14(19)3-8-17(13)18/h3-8,11-12H,9-10H2,1-2H3 NMCPEHIGQKPKAK-UHFFFAOYSA-N 50053211 CHEMBL123640::{2-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 650 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053211&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10829244 103949925 CHEMBL123640 ZINC13758596 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088044 CN(C)CCCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C19H20ClFN2/c1-22(2)11-3-4-14-13-23(17-8-6-16(21)7-9-17)19-10-5-15(20)12-18(14)19/h5-10,12-13H,3-4,11H2,1-2H3 HYJGKLJJZPCABL-UHFFFAOYSA-N 50053210 CHEMBL123094::{3-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-propyl}-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053210&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10544460 103949924 CHEMBL123094 ZINC13758602 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088049 CN(CCN1CCNC1=O)CCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C22H24ClFN4O/c1-26(12-13-27-11-9-25-22(27)29)10-8-16-15-28(19-5-3-18(24)4-6-19)21-7-2-17(23)14-20(16)21/h2-7,14-15H,8-13H2,1H3,(H,25,29) HZPMXBJBHJVLLP-UHFFFAOYSA-N 50053213 1-[2-({2-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-methyl-amino)-ethyl]-imidazolidin-2-one::CHEMBL122113 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053213&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11796106 103949927 CHEMBL122113 ZINC13758591 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088051 CC(C)N1CCN(CCN(C)CCOc2cn(-c3ccc(F)cc3)c3cc(Cl)ccc23)C1=O InChI=1S/C25H30ClFN4O2/c1-18(2)30-13-12-29(25(30)32)11-10-28(3)14-15-33-24-17-31(21-7-5-20(27)6-8-21)23-16-19(26)4-9-22(23)24/h4-9,16-18H,10-15H2,1-3H3 AAJVCKWMBZMPTO-UHFFFAOYSA-N 50053206 1-[2-({2-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yloxy]-ethyl}-methyl-amino)-ethyl]-3-isopropyl-imidazolidin-2-one::CHEMBL122047 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053206 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053206&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10528455 103949920 CHEMBL122047 ZINC13758618 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088056 CN(C)CCSc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C18H18ClFN2S/c1-21(2)9-10-23-18-12-22(15-6-4-14(20)5-7-15)17-8-3-13(19)11-16(17)18/h3-8,11-12H,9-10H2,1-2H3 ZRYMWGZUXUGIKW-UHFFFAOYSA-N 50053203 CHEMBL123027::{2-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylsulfanyl]-ethyl}-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053203&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10736518 103949917 CHEMBL123027 ZINC13758621 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088061 CN1CCN(CCOc2cn(-c3ccc(F)cc3)c3ccc(Cl)cc23)CC1 InChI=1S/C21H23ClFN3O/c1-24-8-10-25(11-9-24)12-13-27-21-15-26(18-5-3-17(23)4-6-18)20-7-2-16(22)14-19(20)21/h2-7,14-15H,8-13H2,1H3 CWVSTEWDEQIXSE-UHFFFAOYSA-N 50053192 5-Chloro-1-(4-fluoro-phenyl)-3-[2-(4-methyl-piperazin-1-yl)-ethoxy]-1H-indole::CHEMBL123584 D(2) dopamine receptor Rattus norvegicus 2.4 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053192&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9886555 103949906 CHEMBL123584 ZINC22938434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088066 CN(C)CCCCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C20H22ClFN2/c1-23(2)12-4-3-5-15-14-24(18-9-7-17(22)8-10-18)20-11-6-16(21)13-19(15)20/h6-11,13-14H,3-5,12H2,1-2H3 GNJLTBRLYYQCLP-UHFFFAOYSA-N 50053189 CHEMBL122384::{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-butyl}-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 4800 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053189&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10497675 103949903 CHEMBL122384 ZINC13758605 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088067 CN(CCCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12)CCN1CCNC1=O InChI=1S/C23H26ClFN4O/c1-27(13-14-28-12-10-26-23(28)30)11-2-3-17-16-29(20-7-5-19(25)6-8-20)22-9-4-18(24)15-21(17)22/h4-9,15-16H,2-3,10-14H2,1H3,(H,26,30) FZFHDXGTARKYSC-UHFFFAOYSA-N 50053212 1-[2-({3-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-propyl}-methyl-amino)-ethyl]-imidazolidin-2-one::CHEMBL122042 D(2) dopamine receptor Rattus norvegicus 190 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053212&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10812487 103949926 CHEMBL122042 ZINC13758603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085778 COc1cc(NC(=O)C(C)C)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C23H28ClN3O3/c1-15(2)22(28)26-20-12-21(30-3)18(11-19(20)24)23(29)25-17-9-10-27(14-17)13-16-7-5-4-6-8-16/h4-8,11-12,15,17H,9-10,13-14H2,1-3H3,(H,25,29)(H,26,28)/t17-/m0/s1 KOGDZZNXDVXRTP-KRWDZBQOSA-N 50052179 CHEMBL93021::N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-isobutyrylamino-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10836365 103949088 CHEMBL93021 ZINC13756895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085785 COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@H]1CCN(C1)C1C2CC3CC(C2)CC1C3 InChI=1S/C26H34ClN3O3/c1-33-23-12-22(29-25(31)16-2-3-16)21(27)11-20(23)26(32)28-19-4-5-30(13-19)24-17-7-14-6-15(9-17)10-18(24)8-14/h11-12,14-19,24H,2-10,13H2,1H3,(H,28,32)(H,29,31)/t14?,15?,17?,18?,19-,24?/m0/s1 UYRXOOUBRAEWNZ-OBBCFLIVSA-N 50052181 CHEMBL92924::N-((S)-1-Adamantan-2-yl-pyrrolidin-3-yl)-5-chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10719212 103949090 CHEMBL92924 ZINC13756915 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085787 COc1cc(NC(=O)C(F)(F)F)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C21H21ClF3N3O3/c1-31-18-10-17(27-20(30)21(23,24)25)16(22)9-15(18)19(29)26-14-7-8-28(12-14)11-13-5-3-2-4-6-13/h2-6,9-10,14H,7-8,11-12H2,1H3,(H,26,29)(H,27,30)/t14-/m0/s1 DIEABLOXDOWYQT-AWEZNQCLSA-N 50052182 CHEMBL330318::N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-(2,2,2-trifluoro-acetylamino)-benzamide D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10837488 103949091 CHEMBL330318 ZINC13756890 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085803 COc1cc(NC(=O)c2ccccc2)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C26H26ClN3O3/c1-33-24-15-23(29-25(31)19-10-6-3-7-11-19)22(27)14-21(24)26(32)28-20-12-13-30(17-20)16-18-8-4-2-5-9-18/h2-11,14-15,20H,12-13,16-17H2,1H3,(H,28,32)(H,29,31)/t20-/m0/s1 ZLDLWKBRAOVFDO-FQEVSTJZSA-N 50052189 4-Benzoylamino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide::CHEMBL91693 D(2) dopamine receptor Rattus norvegicus 630 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052189&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10623982 103949098 CHEMBL91693 ZINC13756907 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085807 COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C19H22ClN3O2/c1-25-18-10-17(21)16(20)9-15(18)19(24)22-14-7-8-23(12-14)11-13-5-3-2-4-6-13/h2-6,9-10,14H,7-8,11-12,21H2,1H3,(H,22,24)/t14-/m0/s1 SJBNXYKTYPFRET-AWEZNQCLSA-N 50052191 4-Amino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide::CHEMBL329106 D(2) dopamine receptor Rattus norvegicus 0.98 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052191&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10570479 103949100 CHEMBL329106 ZINC13756887 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085813 COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C23H26ClN3O3/c1-30-21-12-20(26-22(28)16-7-8-16)19(24)11-18(21)23(29)25-17-9-10-27(14-17)13-15-5-3-2-4-6-15/h2-6,11-12,16-17H,7-10,13-14H2,1H3,(H,25,29)(H,26,28)/t17-/m1/s1 CPVZPPFHQBIJNB-QGZVFWFLSA-N 50052193 CHEMBL319079::N-((R)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 190 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052193&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10693793 103949102 CHEMBL319079 ZINC00600479 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085819 COc1cc(N)c(Cl)cc1C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C19H22ClN3O2/c1-25-18-10-17(21)16(20)9-15(18)19(24)22-14-7-8-23(12-14)11-13-5-3-2-4-6-13/h2-6,9-10,14H,7-8,11-12,21H2,1H3,(H,22,24)/t14-/m1/s1 SJBNXYKTYPFRET-CQSZACIVSA-N 50052194 4-Amino-N-((R)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide::CHEMBL327984 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052194&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44326285 103949103 CHEMBL327984 ZINC13756889 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087985 Fc1ccc(cc1)-n1cc(OCCN(CCN2CCNC2=O)CC#C)c2cc(Cl)ccc12 InChI=1S/C24H24ClFN4O2/c1-2-10-28(12-13-29-11-9-27-24(29)31)14-15-32-23-17-30(20-6-4-19(26)5-7-20)22-8-3-18(25)16-21(22)23/h1,3-8,16-17H,9-15H2,(H,27,31) YCMFJAQXRKBWMW-UHFFFAOYSA-N 50053191 1-[2-({2-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yloxy]-ethyl}-prop-2-ynyl-amino)-ethyl]-imidazolidin-2-one::CHEMBL338022 D(2) dopamine receptor Rattus norvegicus 190 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053191&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10551704 103949905 CHEMBL338022 ZINC13758609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087992 CN(C)CCCOc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C19H20ClFN2O/c1-22(2)10-3-11-24-19-13-23(16-7-5-15(21)6-8-16)18-9-4-14(20)12-17(18)19/h4-9,12-13H,3,10-11H2,1-2H3 DDABWSQTMGPQAB-UHFFFAOYSA-N 50053196 CHEMBL332077::{3-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yloxy]-propyl}-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053196&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10641353 103949910 CHEMBL332077 ZINC13758628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087994 CN(CCOc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12)CCN1CCNC1=O InChI=1S/C22H24ClFN4O2/c1-26(10-11-27-9-8-25-22(27)29)12-13-30-21-15-28(18-5-3-17(24)4-6-18)20-7-2-16(23)14-19(20)21/h2-7,14-15H,8-13H2,1H3,(H,25,29) HGIVBBHIACENDG-UHFFFAOYSA-N 50053193 1-[2-({2-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yloxy]-ethyl}-methyl-amino)-ethyl]-imidazolidin-2-one::CHEMBL421244 D(2) dopamine receptor Rattus norvegicus 5.8 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053193&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9802796 103949907 CHEMBL421244 ZINC00601169 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087995 CN(CCSc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12)CCN1CCNC1=O InChI=1S/C22H24ClFN4OS/c1-26(10-11-27-9-8-25-22(27)29)12-13-30-21-15-28(18-5-3-17(24)4-6-18)20-7-2-16(23)14-19(20)21/h2-7,14-15H,8-13H2,1H3,(H,25,29) GCRNKAUJTRHQHQ-UHFFFAOYSA-N 50053199 1-[2-({2-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylsulfanyl]-ethyl}-methyl-amino)-ethyl]-imidazolidin-2-one::CHEMBL125072 D(2) dopamine receptor Rattus norvegicus 790 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053199&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10647075 103949913 CHEMBL125072 ZINC13758624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087996 CN(CCN1CCNC1=O)CCc1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 InChI=1S/C22H24ClFN4O/c1-26(12-13-27-11-9-25-22(27)29)10-8-16-15-28(19-5-3-18(24)4-6-19)21-14-17(23)2-7-20(16)21/h2-7,14-15H,8-13H2,1H3,(H,25,29) YXKQXQPNOITGIQ-UHFFFAOYSA-N 50053200 1-[2-({2-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-methyl-amino)-ethyl]-imidazolidin-2-one::CHEMBL122269 D(2) dopamine receptor Rattus norvegicus 590 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053200&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645487 103949914 CHEMBL122269 ZINC13758598 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087997 Fc1ccc(cc1)-n1cc(OCCN2CCCCC2)c2cc(Cl)ccc12 InChI=1S/C21H22ClFN2O/c22-16-4-9-20-19(14-16)21(26-13-12-24-10-2-1-3-11-24)15-25(20)18-7-5-17(23)6-8-18/h4-9,14-15H,1-3,10-13H2 GAOSWGAJUGKDAT-UHFFFAOYSA-N 50053198 5-Chloro-1-(4-fluoro-phenyl)-3-(2-piperidin-1-yl-ethoxy)-1H-indole::CHEMBL125291 D(2) dopamine receptor Rattus norvegicus 2.3 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053198&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10499570 103949912 CHEMBL125291 ZINC13758611 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088000 CN(CCCCN1CCNC1=O)Cc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C23H26ClFN4O/c1-27(11-2-3-12-28-13-10-26-23(28)30)15-17-16-29(20-7-5-19(25)6-8-20)22-9-4-18(24)14-21(17)22/h4-9,14,16H,2-3,10-13,15H2,1H3,(H,26,30) OEVXEDITFCYJDW-UHFFFAOYSA-N 50053202 1-(4-{[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylmethyl]-methyl-amino}-butyl)-imidazolidin-2-one::CHEMBL332385 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053202&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10670233 103949916 CHEMBL332385 ZINC13758588 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088002 CN(CCN1CCNC1=O)Cc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C21H22ClFN4O/c1-25(10-11-26-9-8-24-21(26)28)13-15-14-27(18-5-3-17(23)4-6-18)20-7-2-16(22)12-19(15)20/h2-7,12,14H,8-11,13H2,1H3,(H,24,28) FGAZQFHCZPVRQP-UHFFFAOYSA-N 50053188 1-(2-{[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-ylmethyl]-methyl-amino}-ethyl)-imidazolidin-2-one::CHEMBL122018 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053188&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10834872 103949902 CHEMBL122018 ZINC13758586 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088003 Fc1ccc(cc1)-n1cc(OCCN2CCOCC2)c2cc(Cl)ccc12 InChI=1S/C20H20ClFN2O2/c21-15-1-6-19-18(13-15)20(26-12-9-23-7-10-25-11-8-23)14-24(19)17-4-2-16(22)3-5-17/h1-6,13-14H,7-12H2 SXQIOPRIKSIRIW-UHFFFAOYSA-N 50053197 5-Chloro-1-(4-fluoro-phenyl)-3-(2-morpholin-4-yl-ethoxy)-1H-indole::CHEMBL332913 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053197&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10595604 103949911 CHEMBL332913 ZINC13758613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088009 CC(C)N1CCN(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3cc(Cl)ccc23)C1=O InChI=1S/C27H32ClFN4O/c1-19(2)32-16-15-31(27(32)34)14-13-30-11-9-20(10-12-30)25-18-33(23-6-4-22(29)5-7-23)26-17-21(28)3-8-24(25)26/h3-8,17-20H,9-16H2,1-2H3 NIMNILHFXBBMBV-UHFFFAOYSA-N 50001782 (Lu 26-042)1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::1-(2-{4-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL331545 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9826570 103916155 CHEMBL331545 ZINC00598062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088012 CN(C)CCOc1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 InChI=1S/C18H18ClFN2O/c1-21(2)9-10-23-18-12-22(15-6-4-14(20)5-7-15)17-11-13(19)3-8-16(17)18/h3-8,11-12H,9-10H2,1-2H3 ILXSTDBFYIRKOB-UHFFFAOYSA-N 50053207 CHEMBL339919::{2-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yloxy]-ethyl}-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053207&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10544602 103949921 CHEMBL339919 ZINC13758616 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088014 CN(C)CCOc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C18H18ClFN2O/c1-21(2)9-10-23-18-12-22(15-6-4-14(20)5-7-15)17-8-3-13(19)11-16(17)18/h3-8,11-12H,9-10H2,1-2H3 JTXLTPOVZSWTDS-UHFFFAOYSA-N 50053209 CHEMBL125483::{2-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yloxy]-ethyl}-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 2.9 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053209&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10592734 103949923 CHEMBL125483 ZINC13758606 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088015 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088021 CC(C)N1CCN(CCN(C)CCc2cn(-c3ccc(F)cc3)c3cc(Cl)ccc23)C1=O InChI=1S/C25H30ClFN4O/c1-18(2)30-15-14-29(25(30)32)13-12-28(3)11-10-19-17-31(22-7-5-21(27)6-8-22)24-16-20(26)4-9-23(19)24/h4-9,16-18H,10-15H2,1-3H3 NGNPLUIBWZYBFY-UHFFFAOYSA-N 50053208 1-[2-({2-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-methyl-amino)-ethyl]-3-isopropyl-imidazolidin-2-one::CHEMBL331193 D(2) dopamine receptor Rattus norvegicus 190 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053208&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10527817 103949922 CHEMBL331193 ZINC13758601 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088024 CN(CCCN1CCNC1=O)CCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 InChI=1S/C23H26ClFN4O/c1-27(11-2-12-28-14-10-26-23(28)30)13-9-17-16-29(20-6-4-19(25)5-7-20)22-8-3-18(24)15-21(17)22/h3-8,15-16H,2,9-14H2,1H3,(H,26,30) MIOUTALXIGIGMP-UHFFFAOYSA-N 50053205 1-[3-({2-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-methyl-amino)-propyl]-imidazolidin-2-one::CHEMBL341229 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053205&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10788685 103949919 CHEMBL341229 ZINC13758594 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088025 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50088026 CN(CCCN1CCNC1=O)CCc1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 InChI=1S/C23H26ClFN4O/c1-27(11-2-12-28-14-10-26-23(28)30)13-9-17-16-29(20-6-4-19(25)5-7-20)22-15-18(24)3-8-21(17)22/h3-8,15-16H,2,9-14H2,1H3,(H,26,30) ZAQPOHRAWKETHB-UHFFFAOYSA-N 50053195 1-[3-({2-[6-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-ethyl}-methyl-amino)-propyl]-imidazolidin-2-one::CHEMBL332425 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm960159f 10.7270/Q2CZ368W 8809161 Andersen, K; Liljefors, T; Hyttel, J; Perregaard, J H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10432755 103949909 CHEMBL332425 ZINC00601172 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085820 COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@H]1CCN(C1)C1C2CCCC1CCC2 InChI=1S/C25H34ClN3O3/c1-32-22-13-21(28-24(30)17-8-9-17)20(26)12-19(22)25(31)27-18-10-11-29(14-18)23-15-4-2-5-16(23)7-3-6-15/h12-13,15-18,23H,2-11,14H2,1H3,(H,27,31)(H,28,30)/t15?,16?,18-,23?/m0/s1 QRFPXARGJKLHNN-XDHZZZRXSA-N 50052183 CHEMBL94050::N-((S)-1-Bicyclo[3.3.1]non-9-yl-pyrrolidin-3-yl)-5-chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44326212 103949092 CHEMBL94050 ZINC13756913 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085829 COc1cc(NC(=O)C2CCCCC2)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C26H32ClN3O3/c1-33-24-15-23(29-25(31)19-10-6-3-7-11-19)22(27)14-21(24)26(32)28-20-12-13-30(17-20)16-18-8-4-2-5-9-18/h2,4-5,8-9,14-15,19-20H,3,6-7,10-13,16-17H2,1H3,(H,28,32)(H,29,31)/t20-/m0/s1 WBQWTTNQBIPRBR-FQEVSTJZSA-N 50052187 CHEMBL95096::N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-(cyclohexanecarbonyl-amino)-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052187&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10790517 103949096 CHEMBL95096 ZINC13756905 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085830 COc1cc(NC(=O)C2CCC2)c(Cl)cc1C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C24H28ClN3O3/c1-31-22-13-21(27-23(29)17-8-5-9-17)20(25)12-19(22)24(30)26-18-10-11-28(15-18)14-16-6-3-2-4-7-16/h2-4,6-7,12-13,17-18H,5,8-11,14-15H2,1H3,(H,26,30)(H,27,29)/t18-/m1/s1 NAIPHDYWZLQDLJ-GOSISDBHSA-N 50052190 CHEMBL316317::N-((R)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-(cyclobutanecarbonyl-amino)-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 240 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052190&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10646834 103949099 CHEMBL316317 ZINC13756901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085835 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(C1)C1C2CCCC1CCC2 InChI=1S/C22H32ClN3O2/c1-24-19-12-20(28-2)17(11-18(19)23)22(27)25-16-9-10-26(13-16)21-14-5-3-6-15(21)8-4-7-14/h11-12,14-16,21,24H,3-10,13H2,1-2H3,(H,25,27)/t14?,15?,16-,21?/m0/s1 UHNSNEFUZARLIE-SAAHUIRJSA-N 50052196 CHEMBL319597::N-((S)-1-Bicyclo[3.3.1]non-9-yl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide D(2) dopamine receptor Rattus norvegicus 0.81 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052196&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669042 103949105 CHEMBL319597 ZINC26669038 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085836 COc1cc(NC(=O)C2CCCC2)c(Cl)cc1C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C25H30ClN3O3/c1-32-23-14-22(28-24(30)18-9-5-6-10-18)21(26)13-20(23)25(31)27-19-11-12-29(16-19)15-17-7-3-2-4-8-17/h2-4,7-8,13-14,18-19H,5-6,9-12,15-16H2,1H3,(H,27,31)(H,28,30)/t19-/m1/s1 NEMKRNRSIHZCJI-LJQANCHMSA-N 50052188 CHEMBL94200::N-((R)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-(cyclopentanecarbonyl-amino)-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 690 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052188&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10837494 103949097 CHEMBL94200 ZINC13756904 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085837 COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@H]1CCN(CC2CCCCC2)C1 InChI=1S/C23H32ClN3O3/c1-30-21-12-20(26-22(28)16-7-8-16)19(24)11-18(21)23(29)25-17-9-10-27(14-17)13-15-5-3-2-4-6-15/h11-12,15-17H,2-10,13-14H2,1H3,(H,25,29)(H,26,28)/t17-/m0/s1 GOKWZHYWRXDYNW-KRWDZBQOSA-N 50052197 5-Chloro-N-((S)-1-cyclohexylmethyl-pyrrolidin-3-yl)-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide::CHEMBL96703 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052197&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574818 103949106 CHEMBL96703 ZINC13756917 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085840 COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@H]1CCN(C1)C1CCCCC1 InChI=1S/C22H30ClN3O3/c1-29-20-12-19(25-21(27)14-7-8-14)18(23)11-17(20)22(28)24-15-9-10-26(13-15)16-5-3-2-4-6-16/h11-12,14-16H,2-10,13H2,1H3,(H,24,28)(H,25,27)/t15-/m0/s1 MEEMKNVOHUJFSV-HNNXBMFYSA-N 50052199 5-Chloro-N-((S)-1-cyclohexyl-pyrrolidin-3-yl)-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide::CHEMBL96369 D(2) dopamine receptor Rattus norvegicus 84 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052199&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10716980 103949108 CHEMBL96369 ZINC13756909 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085841 CCC(=O)Nc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C22H26ClN3O3/c1-3-21(27)25-19-12-20(29-2)17(11-18(19)23)22(28)24-16-9-10-26(14-16)13-15-7-5-4-6-8-15/h4-8,11-12,16H,3,9-10,13-14H2,1-2H3,(H,24,28)(H,25,27)/t16-/m0/s1 APTCMKUWYITAOW-INIZCTEOSA-N 50052195 CHEMBL93198::N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-propionylamino-benzamide D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10716772 103949104 CHEMBL93198 ZINC13756893 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085842 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 260 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085843 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085856 COc1cc(NC(=O)C2CCCC2)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C25H30ClN3O3/c1-32-23-14-22(28-24(30)18-9-5-6-10-18)21(26)13-20(23)25(31)27-19-11-12-29(16-19)15-17-7-3-2-4-8-17/h2-4,7-8,13-14,18-19H,5-6,9-12,15-16H2,1H3,(H,27,31)(H,28,30)/t19-/m0/s1 NEMKRNRSIHZCJI-IBGZPJMESA-N 50052185 CHEMBL92030::N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-(cyclopentanecarbonyl-amino)-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 740 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052185&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10837493 103949094 CHEMBL92030 ZINC13756903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085859 COc1cc(NC(=O)C=C)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C22H24ClN3O3/c1-3-21(27)25-19-12-20(29-2)17(11-18(19)23)22(28)24-16-9-10-26(14-16)13-15-7-5-4-6-8-15/h3-8,11-12,16H,1,9-10,13-14H2,2H3,(H,24,28)(H,25,27)/t16-/m0/s1 WUDCFECOHMKQLS-INIZCTEOSA-N 50052186 4-Acryloylamino-N-((S)-1-benzyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-benzamide::CHEMBL92192 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052186&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740483 103949095 CHEMBL92192 ZINC13756892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085863 COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@H]1CCN(C1)C1CCCCCC1 InChI=1S/C23H32ClN3O3/c1-30-21-13-20(26-22(28)15-8-9-15)19(24)12-18(21)23(29)25-16-10-11-27(14-16)17-6-4-2-3-5-7-17/h12-13,15-17H,2-11,14H2,1H3,(H,25,29)(H,26,28)/t16-/m0/s1 QEFSPTXBNNUABL-INIZCTEOSA-N 50052184 5-Chloro-N-((S)-1-cycloheptyl-pyrrolidin-3-yl)-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide::CHEMBL92199 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052184&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10646459 103949093 CHEMBL92199 ZINC13756911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085872 COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@H]1CCNC1 InChI=1S/C16H20ClN3O3/c1-23-14-7-13(20-15(21)9-2-3-9)12(17)6-11(14)16(22)19-10-4-5-18-8-10/h6-7,9-10,18H,2-5,8H2,1H3,(H,19,22)(H,20,21)/t10-/m0/s1 BPOPGHCAIIZXBN-JTQLQIEISA-N 50052198 5-Chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-N-(S)-pyrrolidin-3-yl-benzamide::CHEMBL96792 D(2) dopamine receptor Rattus norvegicus 14000 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052198&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10830804 103949107 CHEMBL96792 ZINC13756908 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085876 COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@H]1CCN(CCc2ccccc2)C1 InChI=1S/C24H28ClN3O3/c1-31-22-14-21(27-23(29)17-7-8-17)20(25)13-19(22)24(30)26-18-10-12-28(15-18)11-9-16-5-3-2-4-6-16/h2-6,13-14,17-18H,7-12,15H2,1H3,(H,26,30)(H,27,29)/t18-/m0/s1 UIDILJWJRJJVSD-SFHVURJKSA-N 50052200 5-Chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-N-((S)-1-phenethyl-pyrrolidin-3-yl)-benzamide::CHEMBL91859 D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052200&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10741841 103949109 CHEMBL91859 ZINC26661809 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085877 COc1cc(NC(=O)C2CCC2)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C24H28ClN3O3/c1-31-22-13-21(27-23(29)17-8-5-9-17)20(25)12-19(22)24(30)26-18-10-11-28(15-18)14-16-6-3-2-4-7-16/h2-4,6-7,12-13,17-18H,5,8-11,14-15H2,1H3,(H,26,30)(H,27,29)/t18-/m0/s1 NAIPHDYWZLQDLJ-SFHVURJKSA-N 50052192 CHEMBL315446::N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-(cyclobutanecarbonyl-amino)-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 170 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052192&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797442 103949101 CHEMBL315446 ZINC13756899 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085880 COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C23H26ClN3O3/c1-30-21-12-20(26-22(28)16-7-8-16)19(24)11-18(21)23(29)25-17-9-10-27(14-17)13-15-5-3-2-4-6-15/h2-6,11-12,16-17H,7-10,13-14H2,1H3,(H,25,29)(H,26,28)/t17-/m0/s1 CPVZPPFHQBIJNB-KRWDZBQOSA-N 50052180 CHEMBL328866::N-((S)-1-Benzyl-pyrrolidin-3-yl)-5-chloro-4-(cyclopropanecarbonyl-amino)-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm9601720 10.7270/Q2SB44VK 8709107 Ohmori, J; Maeno, K; Hidaka, K; Nakato, K; Matsumoto, M; Tada, S; Hattori, H; Sakamoto, S; Tsukamoto, S; Usuda, S; Mase, T Yamanouchi Pharmaceutical Company Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052180&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9802631 103949089 CHEMBL328866 ZINC03811831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087046 CN(C)CCCCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C24H33ClN2O/c1-26(2)13-8-3-4-9-14-27-15-12-20-16-23(25)24(28)17-21(20)22(18-27)19-10-6-5-7-11-19/h5-7,10-11,16-17,22,28H,3-4,8-9,12-15,18H2,1-2H3 ZTSNZIXPBUGZCP-UHFFFAOYSA-N 50029340 8-Chloro-3-(6-dimethylamino-hexyl)-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL108764 D(2) dopamine receptor Rattus norvegicus 4130 ChEMBL 10.1021/jm960143p 10.7270/Q26D5S3C 8765528 Shah, JH; Kline, RH; Geter-Douglass, B; Izenwasser, S; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952858 103938411 CHEMBL108764 ZINC03806141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087048 CN(C)c1ccc(\C=C\CN2CCc3cc(Br)c(O)cc3C(C2)c2ccccc2)cc1 InChI=1S/C27H29BrN2O/c1-29(2)23-12-10-20(11-13-23)7-6-15-30-16-14-22-17-26(28)27(31)18-24(22)25(19-30)21-8-4-3-5-9-21/h3-13,17-18,25,31H,14-16,19H2,1-2H3/b7-6+ QYRKSUHOUAAAQR-VOTSOKGWSA-N 50052736 8-Bromo-3-[(E)-3-(4-dimethylamino-phenyl)-allyl]-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL326927 D(2) dopamine receptor Rattus norvegicus 858 ChEMBL 10.1021/jm960143p 10.7270/Q26D5S3C 8765528 Shah, JH; Kline, RH; Geter-Douglass, B; Izenwasser, S; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052736&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10005244 103949548 CHEMBL326927 ZINC03810258 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087049 CN(C)CCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C22H29ClN2O/c1-24(2)11-6-7-12-25-13-10-18-14-21(23)22(26)15-19(18)20(16-25)17-8-4-3-5-9-17/h3-5,8-9,14-15,20,26H,6-7,10-13,16H2,1-2H3 JMLZYVMMUDKHMM-UHFFFAOYSA-N 50029341 8-Chloro-3-(4-dimethylamino-butyl)-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL114375 D(2) dopamine receptor Rattus norvegicus 3450 ChEMBL 10.1021/jm960143p 10.7270/Q26D5S3C 8765528 Shah, JH; Kline, RH; Geter-Douglass, B; Izenwasser, S; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9842468 103938412 CHEMBL114375 ZINC03806137 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087050 CN(C)c1ccc(\C=C\CN2CCc3cc(Cl)c(O)cc3C(C2)c2ccccc2)cc1 InChI=1S/C27H29ClN2O/c1-29(2)23-12-10-20(11-13-23)7-6-15-30-16-14-22-17-26(28)27(31)18-24(22)25(19-30)21-8-4-3-5-9-21/h3-13,17-18,25,31H,14-16,19H2,1-2H3/b7-6+ WNLBCBQNLPTEAJ-VOTSOKGWSA-N 50052734 8-Chloro-3-[(E)-3-(4-dimethylamino-phenyl)-allyl]-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL114228 D(2) dopamine receptor Rattus norvegicus 345 ChEMBL 10.1021/jm960143p 10.7270/Q26D5S3C 8765528 Shah, JH; Kline, RH; Geter-Douglass, B; Izenwasser, S; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10071501 103949546 CHEMBL114228 ZINC03810259 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087053 COc1cc2C(CN(C\C=C\c3ccc(cc3)N(C)C)CCc2cc1Br)c1ccccc1 InChI=1S/C28H31BrN2O/c1-30(2)24-13-11-21(12-14-24)8-7-16-31-17-15-23-18-27(29)28(32-3)19-25(23)26(20-31)22-9-5-4-6-10-22/h4-14,18-19,26H,15-17,20H2,1-3H3/b8-7+ QFAQRVOFZAGAIX-BQYQJAHWSA-N 50052735 CHEMBL114143::{4-[(E)-3-(7-Bromo-8-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-propenyl]-phenyl}-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 2000 ChEMBL 10.1021/jm960143p 10.7270/Q26D5S3C 8765528 Shah, JH; Kline, RH; Geter-Douglass, B; Izenwasser, S; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11799287 103949547 CHEMBL114143 ZINC03810260 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50087056 COc1cc2C(CN(C\C=C\c3ccc(cc3)N(C)C)CCc2cc1Cl)c1ccccc1 InChI=1S/C28H31ClN2O/c1-30(2)24-13-11-21(12-14-24)8-7-16-31-17-15-23-18-27(29)28(32-3)19-25(23)26(20-31)22-9-5-4-6-10-22/h4-14,18-19,26H,15-17,20H2,1-3H3/b8-7+ UIOPJHSPYPVYDX-BQYQJAHWSA-N 50052737 CHEMBL423510::{4-[(E)-3-(7-Chloro-8-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-propenyl]-phenyl}-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 1715 ChEMBL 10.1021/jm960143p 10.7270/Q26D5S3C 8765528 Shah, JH; Kline, RH; Geter-Douglass, B; Izenwasser, S; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10837125 103949549 CHEMBL423510 ZINC03810261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085440 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 190 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086493 C(CN1CCN(CC1)c1ccccn1)C#Cc1cccnc1 InChI=1S/C18H20N4/c1-3-10-20-18(8-1)22-14-12-21(13-15-22)11-4-2-6-17-7-5-9-19-16-17/h1,3,5,7-10,16H,4,11-15H2 AFKFISMAIMRWCI-UHFFFAOYSA-N 50052527 1-Pyridin-2-yl-4-(4-pyridin-3-yl-but-3-ynyl)-piperazine::CHEMBL432972 D(2) dopamine receptor Rattus norvegicus 5388 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052527&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10637409 103949379 CHEMBL432972 ZINC26940685 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086494 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccc2OCCOc2c1 InChI=1S/C23H23NO2/c1-2-7-20(8-3-1)21-11-14-24(15-12-21)13-5-4-6-19-9-10-22-23(18-19)26-17-16-25-22/h1-3,7-11,18H,5,12-17H2 CRULMHGTCPWBCB-UHFFFAOYSA-N 50052526 1-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-but-3-ynyl]-4-phenyl-1,2,3,6-tetrahydro-pyridine::CHEMBL108375 D(2) dopamine receptor Rattus norvegicus 127 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052526&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10831379 103949378 CHEMBL108375 ZINC13757302 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086495 C(CC#Cc1cccnc1)CN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c1-4-10-20(11-5-1)21-12-16-23(17-13-21)15-6-2-3-8-19-9-7-14-22-18-19/h1,4-5,7,9-12,14,18H,2,6,13,15-17H2 HJIACVVLQLKTJY-UHFFFAOYSA-N 50052529 3-[5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-pent-1-ynyl]-pyridine::CHEMBL321828 D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052529&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10614333 103949381 CHEMBL321828 ZINC01533846 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086497 C(CN1CCC(=CC1)c1ccccc1)C#Cc1cccnc1 InChI=1S/C20H20N2/c1-2-9-19(10-3-1)20-11-15-22(16-12-20)14-5-4-7-18-8-6-13-21-17-18/h1-3,6,8-11,13,17H,5,12,14-16H2 QNTNWSQRMBFBSH-UHFFFAOYSA-N 50052528 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL108463 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10827222 103949380 CHEMBL108463 ZINC01533844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086499 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccccc1 InChI=1S/C21H21N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-14H,8,15-18H2 LVLZJQZUFDAJLN-UHFFFAOYSA-N 50052534 4-Phenyl-1-(4-phenyl-but-3-ynyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL110324 D(2) dopamine receptor Rattus norvegicus 284 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10827160 103949386 CHEMBL110324 ZINC13757290 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50084327 COc1cc2CCOC(CCN3CCN(CC3)c3ccc(F)cc3)c2cc1OC InChI=1S/C23H29FN2O3/c1-27-22-15-17-8-14-29-21(20(17)16-23(22)28-2)7-9-25-10-12-26(13-11-25)19-5-3-18(24)4-6-19/h3-6,15-16,21H,7-14H2,1-2H3 PAHAVOZGHBZJNZ-UHFFFAOYSA-N 50026847 1-[2-(6,7-Dimethoxy-isochroman-1-yl)-ethyl]-4-(4-fluoro-phenyl)-piperazine::CHEMBL83915 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13015797 103936431 CHEMBL83915 ZINC13756582 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50084332 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 138 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50084336 COc1ccc(cc1)N1CCN(CC[C@@H]2OCCc3ccccc23)CC1 InChI=1S/C22H28N2O2/c1-25-20-8-6-19(7-9-20)24-15-13-23(14-16-24)12-10-22-21-5-3-2-4-18(21)11-17-26-22/h2-9,22H,10-17H2,1H3/t22-/m0/s1 IAUNACXRZSWWJT-QFIPXVFZSA-N 50051561 1-((S)-2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-piperazine::CHEMBL309730 D(2) dopamine receptor Rattus norvegicus 790 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10784211 103948556 CHEMBL309730 ZINC04618051 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50084337 NS(=O)(=O)c1ccc(cc1)N1CCN(CC[C@H]2OCCc3ccccc23)CC1 InChI=1S/C21H27N3O3S/c22-28(25,26)19-7-5-18(6-8-19)24-14-12-23(13-15-24)11-9-21-20-4-2-1-3-17(20)10-16-27-21/h1-8,21H,9-16H2,(H2,22,25,26)/t21-/m1/s1 WNUQCGWXPNGORO-OAQYLSRUSA-N 50051563 4-[4-((R)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]-benzenesulfonamide::CHEMBL81649::U-101387 D(2) dopamine receptor Rattus norvegicus 5600 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811059 103948558 CHEMBL81649 ZINC05162669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50084341 COc1ccc(cc1)N1CCN(CCC2OCCc3ccccc23)CC1 InChI=1S/C22H28N2O2/c1-25-20-8-6-19(7-9-20)24-15-13-23(14-16-24)12-10-22-21-5-3-2-4-18(21)11-17-26-22/h2-9,22H,10-17H2,1H3 IAUNACXRZSWWJT-UHFFFAOYSA-N 50051562 1-(2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-piperazine::CHEMBL71724 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9863333 103948557 CHEMBL71724 ZINC03812551 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50084347 Fc1ccc(cc1)N1CCN(CCC2OCCc3ccccc23)CC1 InChI=1S/C21H25FN2O/c22-18-5-7-19(8-6-18)24-14-12-23(13-15-24)11-9-21-20-4-2-1-3-17(20)10-16-25-21/h1-8,21H,9-16H2 UKOCGOXTVCIACM-UHFFFAOYSA-N 85067 CAS_170856-41-4::CHEMBL81330::PNU 96415E::PNU-96415E D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9909648 136351167 CHEMBL81330 ZINC04632523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50084352 COc1ccc(cc1)N1CCN(CC[C@H]2OCCc3ccccc23)CC1 InChI=1S/C22H28N2O2/c1-25-20-8-6-19(7-9-20)24-15-13-23(14-16-24)12-10-22-21-5-3-2-4-18(21)11-17-26-22/h2-9,22H,10-17H2,1H3/t22-/m1/s1 IAUNACXRZSWWJT-JOCHJYFZSA-N 50051564 1-((R)-2-Isochroman-1-yl-ethyl)-4-(4-methoxy-phenyl)-piperazine::CHEMBL82591 D(2) dopamine receptor Rattus norvegicus >1800 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11792324 103948559 CHEMBL82591 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50084374 CN1CCN(CC1)C1=Nc2cccnc2Nc2ccc(C)cc12 InChI=1S/C18H21N5/c1-13-5-6-15-14(12-13)18(23-10-8-22(2)9-11-23)21-16-4-3-7-19-17(16)20-15/h3-7,12H,8-11H2,1-2H3,(H,19,20) MMCMKWDIEUZMQB-UHFFFAOYSA-N 50040245 8-Methyl-6-(4-methyl-piperazin-1-yl)-11H-benzo[e]pyrido[3,2-b][1,4]diazepine::CHEMBL63329 D(2) dopamine receptor Rattus norvegicus 530 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040245&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3802 103972305 CHEMBL63329 ZINC53151333 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50084375 NS(=O)(=O)c1ccc(cc1)N1CCN(CC[C@@H]2OCCc3ccccc23)CC1 InChI=1S/C21H27N3O3S/c22-28(25,26)19-7-5-18(6-8-19)24-14-12-23(13-15-24)11-9-21-20-4-2-1-3-17(20)10-16-27-21/h1-8,21H,9-16H2,(H2,22,25,26)/t21-/m0/s1 WNUQCGWXPNGORO-NRFANRHFSA-N 50051565 4-[4-((S)-2-Isochroman-1-yl-ethyl)-piperazin-1-yl]-benzenesulfonamide::4-[4-(2-Isochroman-1-yl-ethyl)-piperazin-1-yl]-benzenesulfonamide::CHEMBL69759::Sonepiprazole D(2) dopamine receptor Rattus norvegicus >4300 ChEMBL 10.1021/jm960084f 10.7270/Q2H1314Z 8691438 TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133079 103948560 CHEMBL69759 980 ZINC03812548 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085444 CN1CCN2[C@H]3CCN(CCCC(=O)c4ccc(F)cc4)CC[C@H]3c3cccc1c23 InChI=1S/C25H30FN3O/c1-27-16-17-29-22-12-15-28(13-3-6-24(30)18-7-9-19(26)10-8-18)14-11-20(22)21-4-2-5-23(27)25(21)29/h2,4-5,7-10,20,22H,3,6,11-17H2,1H3/t20-,22-/m0/s1 ZVZSSCYKMISSIN-UNMCSNQZSA-N 50007661 CHEMBL3233423 D(2) dopamine receptor Rattus norvegicus 148 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007661&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655113 103920931 CHEMBL3233423 ZINC13824777 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085445 Fc1ccc(cc1)C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3CCCN2c13 InChI=1S/C24H27FN2O/c25-19-10-8-17(9-11-19)23(28)7-3-13-26-15-12-22-21(16-26)20-6-1-4-18-5-2-14-27(22)24(18)20/h1,4,6,8-11,21-22H,2-3,5,7,12-16H2/t21-,22-/m0/s1 CSRUCKYTDYTZMI-VXKWHMMOSA-N 50007662 CHEMBL3233427 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007662&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 69432471 103920932 CHEMBL3233427 ZINC13824820 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085446 Fc1ccc(cc1)C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3CCN2c13 InChI=1S/C23H25FN2O/c24-18-8-6-16(7-9-18)22(27)5-2-12-25-13-11-21-20(15-25)19-4-1-3-17-10-14-26(21)23(17)19/h1,3-4,6-9,20-21H,2,5,10-15H2/t20-,21-/m0/s1 VFYQZTSTHAKQER-SFTDATJTSA-N 50007663 CHEMBL3233429 D(2) dopamine receptor Rattus norvegicus 71 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007663&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 69588506 103920933 CHEMBL3233429 ZINC26822703 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085447 Fc1ccc(cc1)C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3SCCN2c13 InChI=1S/C23H25FN2OS/c24-17-8-6-16(7-9-17)21(27)4-2-11-25-12-10-20-19(15-25)18-3-1-5-22-23(18)26(20)13-14-28-22/h1,3,5-9,19-20H,2,4,10-15H2/t19-,20-/m0/s1 FMLFWOCCEJXPCC-PMACEKPBSA-N 50007665 CHEMBL3233431 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007665&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 69514548 103920935 CHEMBL3233431 ZINC13824871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085448 Fc1ccc(cc1)C(=O)CCCN1CC[C@H]2[C@@H](C1)c1cccc3OCCN2c13 InChI=1S/C23H25FN2O2/c24-17-8-6-16(7-9-17)21(27)4-2-11-25-12-10-20-19(15-25)18-3-1-5-22-23(18)26(20)13-14-28-22/h1,3,5-9,19-20H,2,4,10-15H2/t19-,20-/m0/s1 DLXKEWOEEPMPHX-PMACEKPBSA-N 50007666 CHEMBL3233432 D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007666&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44538690 103920936 CHEMBL3233432 ZINC13824837 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50085443 Fc1ccc(cc1)C(=O)CCCN1CC[C@H]2[C@@H](CC1)c1cccc3OCCN2c13 InChI=1S/C24H27FN2O2/c25-18-8-6-17(7-9-18)22(28)4-2-12-26-13-10-19-20-3-1-5-23-24(20)27(15-16-29-23)21(19)11-14-26/h1,3,5-9,19,21H,2,4,10-16H2/t19-,21-/m0/s1 XCUDOUJECKZVAJ-FPOVZHCZSA-N 50007660 CHEMBL3233433 D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/jm401958n 10.7270/Q27D2WNZ 24559051 Li, P; Zhang, Q; Robichaud, AJ; Lee, T; Tomesch, J; Yao, W; Beard, JD; Snyder, GL; Zhu, H; Peng, Y; Hendrick, JP; Vanover, KE; Davis, RE; Mates, S; Wennogle, LP Intra-Cellular Therapies Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007660&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90655112 103920930 CHEMBL3233433 ZINC13824807 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086510 C(CN1CCC(=CC1)c1ccccc1)C#Cc1cnc2ccccc2c1 InChI=1S/C24H22N2/c1-2-9-21(10-3-1)22-13-16-26(17-14-22)15-7-6-8-20-18-23-11-4-5-12-24(23)25-19-20/h1-5,9-13,18-19H,7,14-17H2 VNMWEXMNOPGWQX-UHFFFAOYSA-N 50052536 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-quinoline::CHEMBL108790 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052536&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9905884 103949388 CHEMBL108790 ZINC13757286 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086515 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccc2[nH]ccc2c1 InChI=1S/C23H22N2/c1-2-7-20(8-3-1)21-12-16-25(17-13-21)15-5-4-6-19-9-10-23-22(18-19)11-14-24-23/h1-3,7-12,14,18,24H,5,13,15-17H2 OAJVHYXJWDAZTN-UHFFFAOYSA-N 50052537 5-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-1H-indole::CHEMBL109199 D(2) dopamine receptor Rattus norvegicus 193 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052537&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10711254 103949389 CHEMBL109199 ZINC13757293 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086517 Nc1ccc(cc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c22-21-11-9-18(10-12-21)6-4-5-15-23-16-13-20(14-17-23)19-7-2-1-3-8-19/h1-3,7-13H,5,14-17,22H2 STFIELBPKGAKNX-UHFFFAOYSA-N 50052531 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL108531 D(2) dopamine receptor Rattus norvegicus 0.67 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425024 103949383 CHEMBL108531 ZINC01533849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086518 Nc1ccc(cn1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C20H21N3/c21-20-10-9-17(16-22-20)6-4-5-13-23-14-11-19(12-15-23)18-7-2-1-3-8-18/h1-3,7-11,16H,5,12-15H2,(H2,21,22) KAPNJGZVRYPTJW-UHFFFAOYSA-N 50052530 5-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridin-2-ylamine::CHEMBL109063 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357631 103949382 CHEMBL109063 ZINC26941584 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086520 C(CC#Cc1cnc2ccccc2c1)CN1CCC(=CC1)c1ccccc1 InChI=1S/C25H24N2/c1-4-10-22(11-5-1)23-14-17-27(18-15-23)16-8-2-3-9-21-19-24-12-6-7-13-25(24)26-20-21/h1,4-7,10-14,19-20H,2,8,15-18H2 JJHFMCIAAKWGHM-UHFFFAOYSA-N 50052538 3-[5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-pent-1-ynyl]-quinoline::CHEMBL108186 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052538&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10784214 103949390 CHEMBL108186 ZINC13757288 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086525 C(CN1CCC(=CC1)c1ccccc1)C#Cc1cncc2ccccc12 InChI=1S/C24H22N2/c1-2-8-20(9-3-1)21-13-16-26(17-14-21)15-7-6-11-23-19-25-18-22-10-4-5-12-24(22)23/h1-5,8-10,12-13,18-19H,7,14-17H2 CPBVYXALZPNTBE-UHFFFAOYSA-N 50052539 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-isoquinoline::CHEMBL324445 D(2) dopamine receptor Rattus norvegicus 73 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052539&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10830863 103949391 CHEMBL324445 ZINC13757296 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086526 Fc1ccc(cc1)N1CCN(CCC#Cc2cccnc2)CC1 InChI=1S/C19H20FN3/c20-18-6-8-19(9-7-18)23-14-12-22(13-15-23)11-2-1-4-17-5-3-10-21-16-17/h3,5-10,16H,2,11-15H2 KPSYTMDZRNIFGA-UHFFFAOYSA-N 50052540 1-(4-Fluoro-phenyl)-4-(4-pyridin-3-yl-but-3-ynyl)-piperazine::CHEMBL110843 D(2) dopamine receptor Rattus norvegicus 1673 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052540&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10566851 103949392 CHEMBL110843 ZINC52604065 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086532 C(C#Cc1cnc2ccccc2c1)N1CCC(=CC1)c1ccccc1 InChI=1S/C23H20N2/c1-2-8-20(9-3-1)21-12-15-25(16-13-21)14-6-7-19-17-22-10-4-5-11-23(22)24-18-19/h1-5,8-12,17-18H,13-16H2 WEEOEJDXDFWPPK-UHFFFAOYSA-N 50052541 3-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-prop-1-ynyl]-quinoline::CHEMBL108386 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052541&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10496222 103949393 CHEMBL108386 ZINC26951994 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086536 Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 HGEYJZMMUGWEOT-UHFFFAOYSA-N 50002173 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole D(2) dopamine receptor Rattus norvegicus 9.1 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 219050 103916479 48558 CHEMBL431367 52 ZINC01548439 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086538 C(CN1CCC(=CC1)c1cccs1)C#Cc1cccnc1 InChI=1S/C18H18N2S/c1(5-16-6-3-10-19-15-16)2-11-20-12-8-17(9-13-20)18-7-4-14-21-18/h3-4,6-8,10,14-15H,2,9,11-13H2 JLTOBYGAYFPXPN-UHFFFAOYSA-N 50052544 3-[4-(4-Thiophen-2-yl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL108462 D(2) dopamine receptor Rattus norvegicus 255 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10685233 103949396 CHEMBL108462 ZINC52604067 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086540 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccccn1 InChI=1S/C20H20N2/c1-2-8-18(9-3-1)19-12-16-22(17-13-19)15-7-5-11-20-10-4-6-14-21-20/h1-4,6,8-10,12,14H,7,13,15-17H2 ODQASWLALUMZKF-UHFFFAOYSA-N 50052545 2-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL110488 D(2) dopamine receptor Rattus norvegicus 136 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10565311 103949397 CHEMBL110488 ZINC13757294 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086545 Nc1ccccc1C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c22-21-12-5-4-10-20(21)11-6-7-15-23-16-13-19(14-17-23)18-8-2-1-3-9-18/h1-5,8-10,12-13H,7,14-17,22H2 ANMMAXZZUOHCED-UHFFFAOYSA-N 50052543 2-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL321858 D(2) dopamine receptor Rattus norvegicus 183 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10828224 103949395 CHEMBL321858 ZINC13757299 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086546 Nc1ccc(nc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C20H21N3/c21-19-9-10-20(22-16-19)8-4-5-13-23-14-11-18(12-15-23)17-6-2-1-3-7-17/h1-3,6-7,9-11,16H,5,12-15,21H2 LPLZFZAIOWVRTJ-UHFFFAOYSA-N 50052532 6-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridin-3-ylamine::CHEMBL109101 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086348 103949384 CHEMBL109101 ZINC01533848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086547 Oc1ccc(cc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H21NO/c23-21-11-9-18(10-12-21)6-4-5-15-22-16-13-20(14-17-22)19-7-2-1-3-8-19/h1-3,7-13,23H,5,14-17H2 JLZXBPBMBUIBQC-UHFFFAOYSA-N 50052542 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenol::CHEMBL109171 D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052542&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10614402 103949394 CHEMBL109171 ZINC13757292 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086548 C(CN1CCN(CC1)c1ncccn1)C#Cc1cccnc1 InChI=1S/C17H19N5/c1(5-16-6-3-7-18-15-16)2-10-21-11-13-22(14-12-21)17-19-8-4-9-20-17/h3-4,6-9,15H,2,10-14H2 RMIQBLNIGZBTHS-UHFFFAOYSA-N 50052546 2-[4-(4-Pyridin-3-yl-but-3-ynyl)-piperazin-1-yl]-pyrimidine::CHEMBL110136 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052546&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10589823 103949398 CHEMBL110136 ZINC52604070 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086552 COc1ccc(cc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C22H23NO/c1-24-22-12-10-19(11-13-22)7-5-6-16-23-17-14-21(15-18-23)20-8-3-2-4-9-20/h2-4,8-14H,6,15-18H2,1H3 DRTKYNKXTWRNKR-UHFFFAOYSA-N 50052547 1-[4-(4-Methoxy-phenyl)-but-3-ynyl]-4-phenyl-1,2,3,6-tetrahydro-pyridine::CHEMBL108530 D(2) dopamine receptor Rattus norvegicus 327 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052547&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10543539 103949399 CHEMBL108530 ZINC13757301 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086507 Nc1cccc(c1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c22-21-11-6-8-18(17-21)7-4-5-14-23-15-12-20(13-16-23)19-9-2-1-3-10-19/h1-3,6,8-12,17H,5,13-16,22H2 KHTVRVDYYAMNRK-UHFFFAOYSA-N 50052535 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL108532 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052535&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10780717 103949387 CHEMBL108532 ZINC13757298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086554 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccncc1 InChI=1S/C20H20N2/c1-2-7-19(8-3-1)20-11-16-22(17-12-20)15-5-4-6-18-9-13-21-14-10-18/h1-3,7-11,13-14H,5,12,15-17H2 VPUYNZMAEQVXFX-UHFFFAOYSA-N 50052533 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL110489 D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052533&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10684789 103949385 CHEMBL110489 ZINC01533847 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50086558 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccc2occc2c1 InChI=1S/C23H21NO/c1-2-7-20(8-3-1)21-11-15-24(16-12-21)14-5-4-6-19-9-10-23-22(18-19)13-17-25-23/h1-3,7-11,13,17-18H,5,12,14-16H2 SAPVVBMVHBHWPK-UHFFFAOYSA-N 50052548 1-(4-Benzofuran-5-yl-but-3-ynyl)-4-phenyl-1,2,3,6-tetrahydro-pyridine::CHEMBL419021 D(2) dopamine receptor Rattus norvegicus 440 ChEMBL 10.1021/jm950721m 10.7270/Q23N22GZ 8759640 Glase, SA; Akunne, HC; Heffner, TG; Jaen, JC; MacKenzie, RG; Meltzer, LT; Pugsley, TA; Smith, SJ; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10782455 103949400 CHEMBL419021 ZINC13757304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090292 Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc(c1)C(F)(F)F InChI=1S/C19H23F3N4O2/c20-19(21,22)14-4-3-5-15(12-14)24-10-8-23(9-11-24)13-26-17(27)16-6-1-2-7-25(16)18(26)28/h3-5,12,27H,1-2,6-11,13H2 YEJGEBAXGTVVHO-UHFFFAOYSA-N 50054353 2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL295244 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054353&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54503902 103951003 CHEMBL295244 ZINC13760044 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090294 Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C21H29ClN4O2/c22-17-6-5-7-18(16-17)24-14-12-23(13-15-24)9-3-4-11-26-20(27)19-8-1-2-10-25(19)21(26)28/h5-7,16,27H,1-4,8-15H2 GEJHUUVRXKMAAI-UHFFFAOYSA-N 50054354 2-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL42644 D(2) dopamine receptor Rattus norvegicus 129 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054354&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53833937 103951004 CHEMBL42644 ZINC02183636 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090296 Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C19H25N5O4/c25-18-17-3-1-9-22(17)19(26)23(18)10-2-8-20-11-13-21(14-12-20)15-4-6-16(7-5-15)24(27)28/h4-7,25H,1-3,8-14H2 ACFRJYPCQVVKOZ-UHFFFAOYSA-N 50054356 2-{3-[4-(4-Nitro-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL46377 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53635235 103951006 CHEMBL46377 ZINC04661377 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090297 Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C21H29N5O4/c27-20-19-5-1-2-11-24(19)21(28)25(20)12-4-3-10-22-13-15-23(16-14-22)17-6-8-18(9-7-17)26(29)30/h6-9,27H,1-5,10-16H2 CJXDCIMTVJRODS-UHFFFAOYSA-N 50054357 2-{4-[4-(4-Nitro-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL44876 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054357&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53725051 103951007 CHEMBL44876 ZINC04661420 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090298 Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C21H29FN4O2/c22-17-6-8-18(9-7-17)24-15-13-23(14-16-24)10-3-4-12-26-20(27)19-5-1-2-11-25(19)21(26)28/h6-9,27H,1-5,10-16H2 SFPDTSZEKDBWPO-UHFFFAOYSA-N 50054358 2-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL296413 D(2) dopamine receptor Rattus norvegicus 615.0 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054358&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54303065 103951008 CHEMBL296413 ZINC02183640 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090304 Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F InChI=1S/C20H25F3N4O2/c21-20(22,23)15-4-3-5-16(14-15)25-11-8-24(9-12-25)10-13-27-18(28)17-6-1-2-7-26(17)19(27)29/h3-5,14,28H,1-2,6-13H2 NEBMGQUYDBJBJE-UHFFFAOYSA-N 50054363 2-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL42396 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054363&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54106411 103951013 CHEMBL42396 ZINC13760048 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090305 Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C19H25ClN4O2/c20-15-4-3-5-16(14-15)22-11-8-21(9-12-22)10-13-24-18(25)17-6-1-2-7-23(17)19(24)26/h3-5,14,25H,1-2,6-13H2 OGLSWAFRNKRHIN-UHFFFAOYSA-N 50054364 2-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL46525 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54149083 103951014 CHEMBL46525 ZINC52584321 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090306 Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C17H21ClN4O2/c18-13-3-1-4-14(11-13)20-9-7-19(8-10-20)12-22-16(23)15-5-2-6-21(15)17(22)24/h1,3-4,11,23H,2,5-10,12H2 SRCDZCNVCRHMGY-UHFFFAOYSA-N 50054365 2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL297887 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054365&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54320191 103951015 CHEMBL297887 ZINC13760033 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090308 Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1ccccc1 InChI=1S/C21H30N4O2/c26-20-19-10-4-5-12-24(19)21(27)25(20)13-7-6-11-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h1-3,8-9,26H,4-7,10-17H2 FVWAQEKBJIPULJ-UHFFFAOYSA-N 50054366 2-[4-(4-Phenyl-piperazin-1-yl)-butyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL42404 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054366&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53821170 103951016 CHEMBL42404 ZINC13760064 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090318 Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1ccccc1 InChI=1S/C18H24N4O2/c23-17-16-8-4-5-9-21(16)18(24)22(17)14-19-10-12-20(13-11-19)15-6-2-1-3-7-15/h1-3,6-7,23H,4-5,8-14H2 PYDQDHZXMJZQLP-UHFFFAOYSA-N 50054372 2-(4-Phenyl-piperazin-1-ylmethyl)-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL42654 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054372&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54214418 103951022 CHEMBL42654 ZINC13760039 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090322 COc1ccccc1N1CCN(CCn2c(O)c3CCCCn3c2=O)CC1 InChI=1S/C20H28N4O3/c1-27-18-8-3-2-6-16(18)22-13-10-21(11-14-22)12-15-24-19(25)17-7-4-5-9-23(17)20(24)26/h2-3,6,8,25H,4-5,7,9-15H2,1H3 AKIGPOQNPHYIOW-UHFFFAOYSA-N 50054361 2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL296713 D(2) dopamine receptor Rattus norvegicus 246 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054361&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53647464 103951011 CHEMBL296713 ZINC52584304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090324 Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C17H21FN4O2/c18-13-3-5-14(6-4-13)20-10-8-19(9-11-20)12-22-16(23)15-2-1-7-21(15)17(22)24/h3-6,23H,1-2,7-12H2 QPMIMXRKACZEBE-UHFFFAOYSA-N 50054377 2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL42881 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54240220 103951027 CHEMBL42881 ZINC13760037 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090325 Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1ccccc1 InChI=1S/C18H24N4O2/c23-17-16-7-4-8-21(16)18(24)22(17)14-11-19-9-12-20(13-10-19)15-5-2-1-3-6-15/h1-3,5-6,23H,4,7-14H2 GXHDXIGJFSRVPQ-UHFFFAOYSA-N 50054376 2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL296724 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054376&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53862241 103951026 CHEMBL296724 ZINC53112855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090326 Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1ccccc1 InChI=1S/C19H26N4O2/c24-18-17-8-4-5-9-22(17)19(25)23(18)15-12-20-10-13-21(14-11-20)16-6-2-1-3-7-16/h1-3,6-7,24H,4-5,8-15H2 NBULFPJENWKOME-UHFFFAOYSA-N 50054352 2-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL291165 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54102970 103951002 CHEMBL291165 ZINC52584312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090328 Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C19H25ClN4O2/c20-15-4-1-5-16(14-15)22-12-10-21(11-13-22)7-3-9-24-18(25)17-6-2-8-23(17)19(24)26/h1,4-5,14,25H,2-3,6-13H2 DYWYXBNPBBDJJK-UHFFFAOYSA-N 50054367 2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL416984 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054367&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53786528 103951017 CHEMBL416984 ZINC00641745 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090329 Oc1c2CCCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F InChI=1S/C22H29F3N4O2/c23-22(24,25)17-6-5-7-18(16-17)27-14-12-26(13-15-27)9-3-4-11-29-20(30)19-8-1-2-10-28(19)21(29)31/h5-7,16,30H,1-4,8-15H2 VSSOJVHAELBITH-UHFFFAOYSA-N 50054355 2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL417709 D(2) dopamine receptor Rattus norvegicus 90.6 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54408925 103951005 CHEMBL417709 ZINC02183638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090332 Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C19H25FN4O2/c20-15-4-6-16(7-5-15)22-12-9-21(10-13-22)11-14-24-18(25)17-3-1-2-8-23(17)19(24)26/h4-7,25H,1-3,8-14H2 ZLAYCCNBHCAKAS-UHFFFAOYSA-N 50054375 2-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL289784 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054375&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54552727 103951025 CHEMBL289784 ZINC52584240 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090333 Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C20H27FN4O2/c21-16-5-7-17(8-6-16)23-14-12-22(13-15-23)9-1-2-10-25-19(26)18-4-3-11-24(18)20(25)27/h5-8,26H,1-4,9-15H2 RPKOIJUATMPDCZ-UHFFFAOYSA-N 50054378 2-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL46885 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54278934 103951028 CHEMBL46885 ZINC02183632 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090335 COc1ccccc1N1CCN(CCn2c(O)c3CCCn3c2=O)CC1 InChI=1S/C19H26N4O3/c1-26-17-7-3-2-5-15(17)21-12-9-20(10-13-21)11-14-23-18(24)16-6-4-8-22(16)19(23)25/h2-3,5,7,24H,4,6,8-14H2,1H3 CVLMZZGNUFHGHY-UHFFFAOYSA-N 50054380 2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL46535 D(2) dopamine receptor Rattus norvegicus 361 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53742272 103951030 CHEMBL46535 ZINC53244629 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090337 Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1ccccc1 InChI=1S/C19H26N4O2/c24-18-17-8-4-10-22(17)19(25)23(18)11-5-9-20-12-14-21(15-13-20)16-6-2-1-3-7-16/h1-3,6-7,24H,4-5,8-15H2 FYXVLQWAEZZMOG-UHFFFAOYSA-N 50054374 2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL290203 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53825670 103951024 CHEMBL290203 ZINC13760050 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090339 Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C18H23N5O4/c24-17-16-2-1-7-21(16)18(25)22(17)13-10-19-8-11-20(12-9-19)14-3-5-15(6-4-14)23(26)27/h3-6,24H,1-2,7-13H2 JYDJLEOOLSEWIB-UHFFFAOYSA-N 50054373 2-{2-[4-(4-Nitro-phenyl)-piperazin-1-yl]-ethyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL46651 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054373&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53980843 103951023 CHEMBL46651 ZINC19911479 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090342 Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C20H27N5O4/c26-19-18-4-1-2-10-23(18)20(27)24(19)11-3-9-21-12-14-22(15-13-21)16-5-7-17(8-6-16)25(28)29/h5-8,26H,1-4,9-15H2 DIJVTWSTMHQSKL-UHFFFAOYSA-N 50054384 2-{3-[4-(4-Nitro-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL298286 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054384&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53761772 103951034 CHEMBL298286 ZINC13760060 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090346 Oc1c2CCCCn2c(=O)n1CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C19H25N5O4/c25-18-17-3-1-2-8-22(17)19(26)23(18)14-11-20-9-12-21(13-10-20)15-4-6-16(7-5-15)24(27)28/h4-7,25H,1-3,8-14H2 XDFZHNZGCJKQNJ-UHFFFAOYSA-N 50054385 2-{2-[4-(4-Nitro-phenyl)-piperazin-1-yl]-ethyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL42219 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054385&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54463499 103951035 CHEMBL42219 ZINC19911483 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090352 Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(c1)C(F)(F)F InChI=1S/C21H27F3N4O2/c22-21(23,24)16-5-3-6-17(15-16)26-13-11-25(12-14-26)8-4-10-28-19(29)18-7-1-2-9-27(18)20(28)30/h3,5-6,15,29H,1-2,4,7-14H2 RSHQPXYUIIIOBG-UHFFFAOYSA-N 50054391 2-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL45253 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054391&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54283278 103951041 CHEMBL45253 ZINC00641753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090356 Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F InChI=1S/C21H27F3N4O2/c22-21(23,24)16-5-3-6-17(15-16)26-13-11-25(12-14-26)8-1-2-9-28-19(29)18-7-4-10-27(18)20(28)30/h3,5-6,15,29H,1-2,4,7-14H2 UODONYLPLREJMC-UHFFFAOYSA-N 50054393 2-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL46918 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54363499 103951043 CHEMBL46918 ZINC02183630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090360 Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C20H27N5O4/c26-19-18-4-3-11-23(18)20(27)24(19)10-2-1-9-21-12-14-22(15-13-21)16-5-7-17(8-6-16)25(28)29/h5-8,26H,1-4,9-15H2 VVPGFENXTXQANW-UHFFFAOYSA-N 50054382 2-{4-[4-(4-Nitro-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL47040 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54413211 103951032 CHEMBL47040 ZINC13760062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090369 COc1ccccc1N1CCN(Cn2c(O)c3CCCn3c2=O)CC1 InChI=1S/C18H24N4O3/c1-25-16-7-3-2-5-14(16)20-11-9-19(10-12-20)13-22-17(23)15-6-4-8-21(15)18(22)24/h2-3,5,7,23H,4,6,8-13H2,1H3 LVQFRSXUJYYCIN-UHFFFAOYSA-N 50054370 2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL46471 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054370&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54055023 103951020 CHEMBL46471 ZINC13760031 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090374 Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C18H23FN4O2/c19-14-3-5-15(6-4-14)21-11-8-20(9-12-21)10-13-23-17(24)16-2-1-7-22(16)18(23)25/h3-6,24H,1-2,7-13H2 UWIURJNZJLHTCF-UHFFFAOYSA-N 50054396 2-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL432495 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054396&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54375710 103951046 CHEMBL432495 ZINC13762182 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090376 Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1cccc(c1)C(F)(F)F InChI=1S/C19H23F3N4O2/c20-19(21,22)14-3-1-4-15(13-14)24-10-7-23(8-11-24)9-12-26-17(27)16-5-2-6-25(16)18(26)28/h1,3-4,13,27H,2,5-12H2 KTWHHFUQOHNBFT-UHFFFAOYSA-N 50054386 2-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL47200 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054386&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54013289 103951036 CHEMBL47200 ZINC53244632 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090380 Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C20H27ClN4O2/c21-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-1-2-9-25-19(26)18-7-4-10-24(18)20(25)27/h3,5-6,15,26H,1-2,4,7-14H2 RHDBPRGCLWGKRU-UHFFFAOYSA-N 50054351 2-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL290039 D(2) dopamine receptor Rattus norvegicus 151 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54266515 103951001 CHEMBL290039 ZINC02183628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090384 Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C18H23N5O4/c24-17-16-3-1-2-8-21(16)18(25)22(17)13-19-9-11-20(12-10-19)14-4-6-15(7-5-14)23(26)27/h4-7,24H,1-3,8-13H2 SHZFDXOURORPDU-UHFFFAOYSA-N 50054397 2-[4-(4-Nitro-phenyl)-piperazin-1-ylmethyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL46862 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54306634 103951047 CHEMBL46862 ZINC19911474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090385 COc1ccccc1N1CCN(CCCn2c(O)c3CCCCn3c2=O)CC1 InChI=1S/C21H30N4O3/c1-28-19-9-3-2-7-17(19)23-15-13-22(14-16-23)10-6-12-25-20(26)18-8-4-5-11-24(18)21(25)27/h2-3,7,9,26H,4-6,8,10-16H2,1H3 MJTWWJNATKZTMM-UHFFFAOYSA-N 50054387 2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL43992 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054387&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54076093 103951037 CHEMBL43992 ZINC00641749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090392 Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccccc1 InChI=1S/C17H22N4O2/c22-16-15-7-4-8-20(15)17(23)21(16)13-18-9-11-19(12-10-18)14-5-2-1-3-6-14/h1-3,5-6,22H,4,7-13H2 XFPIYZXESSEJJG-UHFFFAOYSA-N 50054388 2-(4-Phenyl-piperazin-1-ylmethyl)-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL46470 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054388&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54467011 103951038 CHEMBL46470 ZINC13760029 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090393 COc1ccccc1N1CCN(CCCCn2c(O)c3CCCCn3c2=O)CC1 InChI=1S/C22H32N4O3/c1-29-20-10-3-2-8-18(20)24-16-14-23(15-17-24)11-6-7-13-26-21(27)19-9-4-5-12-25(19)22(26)28/h2-3,8,10,27H,4-7,9,11-17H2,1H3 IICAHJWMSPQGQW-UHFFFAOYSA-N 50054362 2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL46881 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054362&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53917533 103951012 CHEMBL46881 ZINC02183634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090394 COc1ccccc1N1CCN(CCCCn2c(O)c3CCCn3c2=O)CC1 InChI=1S/C21H30N4O3/c1-28-19-9-3-2-7-17(19)23-15-13-22(14-16-23)10-4-5-11-25-20(26)18-8-6-12-24(18)21(25)27/h2-3,7,9,26H,4-6,8,10-16H2,1H3 DVKSOQUUNYQKSE-UHFFFAOYSA-N 50054395 2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL42810 D(2) dopamine receptor Rattus norvegicus 107 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53781250 103951045 CHEMBL42810 ZINC02183626 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090397 Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C17H21N5O4/c23-16-15-2-1-7-20(15)17(24)21(16)12-18-8-10-19(11-9-18)13-3-5-14(6-4-13)22(25)26/h3-6,23H,1-2,7-12H2 JZSYHNVMFOIPBS-UHFFFAOYSA-N 50054360 2-[4-(4-Nitro-phenyl)-piperazin-1-ylmethyl]-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL295527 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054360&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53983286 103951010 CHEMBL295527 ZINC13762178 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090399 Oc1c2CCCn2c(=O)n1CCN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C18H23ClN4O2/c19-14-3-1-4-15(13-14)21-10-7-20(8-11-21)9-12-23-17(24)16-5-2-6-22(16)18(23)25/h1,3-4,13,24H,2,5-12H2 UIXZAOYKUAJCAV-UHFFFAOYSA-N 50054379 2-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL46802 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054379&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54355682 103951029 CHEMBL46802 ZINC53244627 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090406 COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3 SJDOMIRMMUGQQK-UHFFFAOYSA-N 82517 2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione::CAS_107966::CHEMBL126632::CHEMBL8618::NAN-190::NSC_107966 D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4431 136350487 64123 CHEMBL8618CHEMBL126632 ZINC01537496 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090409 Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C18H23ClN4O2/c19-14-4-3-5-15(12-14)21-10-8-20(9-11-21)13-23-17(24)16-6-1-2-7-22(16)18(23)25/h3-5,12,24H,1-2,6-11,13H2 AOLMYMJZZPWPCQ-UHFFFAOYSA-N 50054394 2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL297844 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054394&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53653730 103951044 CHEMBL297844 ZINC13760042 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090412 Oc1c2CCCCn2c(=O)n1CN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C18H23FN4O2/c19-14-4-6-15(7-5-14)21-11-9-20(10-12-21)13-23-17(24)16-3-1-2-8-22(16)18(23)25/h4-7,24H,1-3,8-13H2 FLWGJXIKNYGDOK-UHFFFAOYSA-N 50054390 2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL46672 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054390&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53806171 103951040 CHEMBL46672 ZINC13760046 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090413 Oc1c2CCCn2c(=O)n1CCCCN1CCN(CC1)c1ccccc1 InChI=1S/C20H28N4O2/c25-19-18-9-6-12-23(18)20(26)24(19)11-5-4-10-21-13-15-22(16-14-21)17-7-2-1-3-8-17/h1-3,7-8,25H,4-6,9-16H2 SNLRWEAHIJHWLJ-UHFFFAOYSA-N 50054371 2-[4-(4-Phenyl-piperazin-1-yl)-butyl]-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL43332 D(2) dopamine receptor Rattus norvegicus 416.0 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054371&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54314862 103951021 CHEMBL43332 ZINC02183624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090414 Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(c1)C(F)(F)F InChI=1S/C20H25F3N4O2/c21-20(22,23)15-4-1-5-16(14-15)25-12-10-24(11-13-25)7-3-9-27-18(28)17-6-2-8-26(17)19(27)29/h1,4-5,14,28H,2-3,6-13H2 XQXOHKXFRRASHC-UHFFFAOYSA-N 50054392 2-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL42706 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054392&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54483869 103951042 CHEMBL42706 ZINC13760052 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090429 Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C20H27FN4O2/c21-16-5-7-17(8-6-16)23-14-12-22(13-15-23)9-3-11-25-19(26)18-4-1-2-10-24(18)20(25)27/h5-8,26H,1-4,9-15H2 UNINGNCNGLMMRX-UHFFFAOYSA-N 50054383 2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL45007::cid_3587301 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54362286 103951033 CHEMBL45007 ZINC00641757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090431 COc1ccccc1N1CCN(Cn2c(O)c3CCCCn3c2=O)CC1 InChI=1S/C19H26N4O3/c1-26-17-8-3-2-6-15(17)21-12-10-20(11-13-21)14-23-18(24)16-7-4-5-9-22(16)19(23)25/h2-3,6,8,24H,4-5,7,9-14H2,1H3 AQSDXGYFPPUAQZ-UHFFFAOYSA-N 50054398 2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL295168 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53657171 103951048 CHEMBL295168 ZINC29403018 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090432 COc1ccccc1N1CCN(CCCn2c(O)c3CCCn3c2=O)CC1 InChI=1S/C20H28N4O3/c1-27-18-8-3-2-6-16(18)22-14-12-21(13-15-22)9-5-11-24-19(25)17-7-4-10-23(17)20(24)26/h2-3,6,8,25H,4-5,7,9-15H2,1H3 OFPNXUWVJHQEMH-UHFFFAOYSA-N 50054359 2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL289873 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054359&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54147799 103951009 CHEMBL289873 ZINC00641742 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090434 Oc1c2CCCn2c(=O)n1CCCN1CCN(CC1)c1ccc(F)cc1 InChI=1S/C19H25FN4O2/c20-15-4-6-16(7-5-15)22-13-11-21(12-14-22)8-2-10-24-18(25)17-3-1-9-23(17)19(24)26/h4-7,25H,1-3,8-14H2 QBWXQQARRQCRME-UHFFFAOYSA-N 50054369 2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL46677 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054369&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54219979 103951019 CHEMBL46677 ZINC13760054 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090437 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 852.0 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090440 Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1cccc(c1)C(F)(F)F InChI=1S/C18H21F3N4O2/c19-18(20,21)13-3-1-4-14(11-13)23-9-7-22(8-10-23)12-25-16(26)15-5-2-6-24(15)17(25)27/h1,3-4,11,26H,2,5-10,12H2 PUBYYTQEIXPINL-UHFFFAOYSA-N 50054389 2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL430567 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054389&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54208265 103951039 CHEMBL430567 ZINC13760035 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090442 Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C20H27ClN4O2/c21-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)18-7-1-2-9-24(18)20(25)27/h3,5-6,15,26H,1-2,4,7-14H2 LOCLCEAWIAEMFK-UHFFFAOYSA-N 50054368 2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL44786 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054368&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54043712 103951018 CHEMBL44786 ZINC13760058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50090444 Oc1c2CCCCn2c(=O)n1CCCN1CCN(CC1)c1ccccc1 InChI=1S/C20H28N4O2/c25-19-18-9-4-5-11-23(18)20(26)24(19)12-6-10-21-13-15-22(16-14-21)17-7-2-1-3-8-17/h1-3,7-8,25H,4-6,9-16H2 BEQRMOOEDQOVLT-UHFFFAOYSA-N 50054381 2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL41978 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960416g 10.7270/Q2WS8SBN 8893838 Lopez-Rodriguez, ML; Rosado, ML; Benhamu, B; Morcillo, MJ; Sanz, AM; Orensanz, L; Beneitez, ME; Fuentes, JA; Manzanares, J Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054381&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53678112 103951031 CHEMBL41978 ZINC13760056 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50091827 O=C1CN(CN2CCN(CC2)c2cccc3ccccc23)C(=O)[C@@H]2CCCN12 InChI=1S/C22H26N4O2/c27-21-15-25(22(28)20-9-4-10-26(20)21)16-23-11-13-24(14-12-23)19-8-3-6-17-5-1-2-7-18(17)19/h1-3,5-8,20H,4,9-16H2/t20-/m0/s1 CTZWGZSINBFHFD-FQEVSTJZSA-N 50164450 (S)-2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione::CHEMBL370758 D(2) dopamine receptor Rattus norvegicus 192 ChEMBL 10.1021/jm048999e 10.7270/Q23F4PNB 15801844 López-Rodríguez, ML; Tejada, I; Morcillo, MJ; Fernández, E; Benhamú, B; Tejada, I; Ayala, D; Viso, A; Pardo, L; Manzanares, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164450&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11291892 104050231 CHEMBL370758 ZINC28475410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093332 COc1ccccc1N1CCN(CCNC(=O)c2ccccc2)CC1 InChI=1S/C20H25N3O2/c1-25-19-10-6-5-9-18(19)23-15-13-22(14-16-23)12-11-21-20(24)17-7-3-2-4-8-17/h2-10H,11-16H2,1H3,(H,21,24) VINJWMQYVRCWQC-UHFFFAOYSA-N 50056024 CHEMBL106854::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13318464 103952430 CHEMBL106854 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093333 COc1ccccc1N1CCN(CCNC(=N)C2CCCCC2)CC1 InChI=1S/C20H32N4O/c1-25-19-10-6-5-9-18(19)24-15-13-23(14-16-24)12-11-22-20(21)17-7-3-2-4-8-17/h5-6,9-10,17H,2-4,7-8,11-16H2,1H3,(H2,21,22) RTZMZOSPFYMPPG-UHFFFAOYSA-N 50056025 CHEMBL107903::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-cyclohexanecarboxamidine D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056025&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10807433 103952431 CHEMBL107903 ZINC13760895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093335 COc1ccccc1N1CCN(CCCCc2ccc(F)cc2)CC1 InChI=1S/C21H27FN2O/c1-25-21-8-3-2-7-20(21)24-16-14-23(15-17-24)13-5-4-6-18-9-11-19(22)12-10-18/h2-3,7-12H,4-6,13-17H2,1H3 OHHOLPBLYOJVEF-UHFFFAOYSA-N 50056026 1-[4-(4-Fluoro-phenyl)-butyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL105345 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593421 103952432 CHEMBL105345 ZINC13760896 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093336 OC[C@@H]1COc2c(O1)cccc2N1CCNCC1 InChI=1S/C13H18N2O3/c16-8-10-9-17-13-11(2-1-3-12(13)18-10)15-6-4-14-5-7-15/h1-3,10,14,16H,4-9H2/t10-/m1/s1 BOXCVCJOJXRNFC-SNVBAGLBSA-N 50056028 ((R)-5-Piperazin-1-yl-2,3-dihydro-benzo[1,4]dioxin-2-yl)-methanol::CHEMBL106413 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44336171 103952434 CHEMBL106413 ZINC13760899 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093337 COc1ccccc1N1CCN(CCNC(=O)c2cccs2)CC1 InChI=1S/C18H23N3O2S/c1-23-16-6-3-2-5-15(16)21-12-10-20(11-13-21)9-8-19-18(22)17-7-4-14-24-17/h2-7,14H,8-13H2,1H3,(H,19,22) XCSPUFATFOILKU-UHFFFAOYSA-N 50056027 CHEMBL419910::Thiophene-2-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10617524 103952433 CHEMBL419910 ZINC53228166 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093339 COc1ccccc1N1CCN(CCNC(=O)c2cccnc2)CC1 InChI=1S/C19H24N4O2/c1-25-18-7-3-2-6-17(18)23-13-11-22(12-14-23)10-9-21-19(24)16-5-4-8-20-15-16/h2-8,15H,9-14H2,1H3,(H,21,24) RPFDZEAPDWUCAQ-UHFFFAOYSA-N 50034283 CHEMBL26447::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-nicotinamide D(2) dopamine receptor Rattus norvegicus 570 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11724818 103942484 CHEMBL26447 ZINC13740980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093340 COc1ccccc1N1CCN(CCNC(=O)c2ccc[nH]2)CC1 InChI=1S/C18H24N4O2/c1-24-17-7-3-2-6-16(17)22-13-11-21(12-14-22)10-9-20-18(23)15-5-4-8-19-15/h2-8,19H,9-14H2,1H3,(H,20,23) QCDUWXTWVDOIDM-UHFFFAOYSA-N 50034285 1H-Pyrrole-2-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL278799 D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034285&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10087901 103942486 CHEMBL278799 ZINC13740977 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093341 Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)c1cccc2OCCOc12 InChI=1S/C21H24FN3O3/c22-17-6-4-16(5-7-17)21(26)23-8-9-24-10-12-25(13-11-24)18-2-1-3-19-20(18)28-15-14-27-19/h1-7H,8-15H2,(H,23,26) GTEYGWXMYSXCRZ-UHFFFAOYSA-N 50039824 CHEMBL81728::N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin-1-yl]-ethyl}-4-fluoro-benzamide D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039824&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10430183 103947019 CHEMBL81728 ZINC13738303 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093343 COc1ccccc1N1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C21H25FN2O2/c1-26-21-7-3-2-5-19(21)24-15-13-23(14-16-24)12-4-6-20(25)17-8-10-18(22)11-9-17/h2-3,5,7-11H,4,6,12-16H2,1H3 IRYFCWPNDIUQOW-UHFFFAOYSA-N 50019959 1-(4-Fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one::1-(4-Fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one(fluanisone)::CHEMBL58792::Fluanisone D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15139 103930882 CHEMBL58792 ZINC04213325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093344 COc1ccccc1N1CCN(CC\C=C\c2ccc(F)cc2)CC1 InChI=1S/C21H25FN2O/c1-25-21-8-3-2-7-20(21)24-16-14-23(15-17-24)13-5-4-6-18-9-11-19(22)12-10-18/h2-4,6-12H,5,13-17H2,1H3/b6-4+ RZIVFBRAKJMQQL-GQCTYLIASA-N 50056023 1-[(E)-4-(4-Fluoro-phenyl)-but-3-enyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL104805 D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056023&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10688524 103952429 CHEMBL104805 ZINC13760897 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093347 COc1ccccc1N1CCN(CCNC(=O)c2ccncc2)CC1 InChI=1S/C19H24N4O2/c1-25-18-5-3-2-4-17(18)23-14-12-22(13-15-23)11-10-21-19(24)16-6-8-20-9-7-16/h2-9H,10-15H2,1H3,(H,21,24) IQYRBWJVVBVMOS-UHFFFAOYSA-N 50056031 CHEMBL104593::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isonicotinamide D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640907 103952437 CHEMBL104593 ZINC13760892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093352 COc1ccccc1N1CCN(CCNC(=O)c2ccco2)CC1 InChI=1S/C18H23N3O3/c1-23-16-6-3-2-5-15(16)21-12-10-20(11-13-21)9-8-19-18(22)17-7-4-14-24-17/h2-7,14H,8-13H2,1H3,(H,19,22) PVJYNFRNHSYBAL-UHFFFAOYSA-N 50056032 CHEMBL104204::Furan-2-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide D(2) dopamine receptor Rattus norvegicus 73 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10735128 103952438 CHEMBL104204 ZINC11900191 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093354 COc1ccccc1N1CCNCC1 InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 VNZLQLYBRIOLFZ-UHFFFAOYSA-N 50001862 (N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl)-piperazine::1-(2-Methoxy-phenyl)-piperazine::2-METHOXYPHENYLPIPERAZINE::4-(2-Methoxy-phenyl)-piperazin-1-ium::CHEMBL9666 D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1346 103916229 CHEMBL9666 280 ZINC00012687 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093356 Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)c1cccc2ccoc12 InChI=1S/C21H22FN3O2/c22-18-6-4-17(5-7-18)21(26)23-9-10-24-11-13-25(14-12-24)19-3-1-2-16-8-15-27-20(16)19/h1-8,15H,9-14H2,(H,23,26) OETSERFTYLQOCP-UHFFFAOYSA-N 50020178 CHEMBL294633::CHEMBL555633::N-[2-(4-Benzofuran-7-yl-piperazin-1-yl)-ethyl]-4-fluoro-benzamide D(2) dopamine receptor Rattus norvegicus 5.3 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020178&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9999042 103931095 CHEMBL555633CHEMBL294633 ZINC12356235 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093357 COc1ccccc1N1CCN(CCOCc2ccc(F)cc2)CC1 InChI=1S/C20H25FN2O2/c1-24-20-5-3-2-4-19(20)23-12-10-22(11-13-23)14-15-25-16-17-6-8-18(21)9-7-17/h2-9H,10-16H2,1H3 BNKBVKYOPJQHNN-UHFFFAOYSA-N 50056030 1-[2-(4-Fluoro-benzyloxy)-ethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL323982 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056030&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23276578 103952436 CHEMBL323982 ZINC13760898 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093359 C1CN(CCN1)c1cccc2ccoc12 InChI=1S/C12H14N2O/c1-2-10-4-9-15-12(10)11(3-1)14-7-5-13-6-8-14/h1-4,9,13H,5-8H2 KFVKNZPFYQDNAE-UHFFFAOYSA-N 50035042 1-Benzofuran-7-yl-piperazine::CHEMBL61032 D(2) dopamine receptor Rattus norvegicus 780 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035042&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10465458 103943112 CHEMBL61032 ZINC12355893 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093361 C1CN(CCN1)c1cccc2OCCOc12 InChI=1S/C12H16N2O2/c1-2-10(14-6-4-13-5-7-14)12-11(3-1)15-8-9-16-12/h1-3,13H,4-9H2 WVLHGCRWEHCIOT-UHFFFAOYSA-N 50035057 (eltoprazine)1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine::1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazine::CHEMBL282614::Eltoprazine D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035057&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65853 103943127 CHEMBL282614 ZINC00001347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093362 COc1ccccc1N1CCN(CCNC(=O)C2CCCCC2)CC1 InChI=1S/C20H31N3O2/c1-25-19-10-6-5-9-18(19)23-15-13-22(14-16-23)12-11-21-20(24)17-7-3-2-4-8-17/h5-6,9-10,17H,2-4,7-8,11-16H2,1H3,(H,21,24) HJFABTUBWNFTBH-UHFFFAOYSA-N 50056034 CHEMBL108229::Cyclohexanecarboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9819571 103952440 CHEMBL108229 ZINC53151260 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093363 C1CN(CCN1)c1ccccc1 InChI=1S/C10H14N2/c1-2-4-10(5-3-1)12-8-6-11-7-9-12/h1-5,11H,6-9H2 YZTJYBJCZXZGCT-UHFFFAOYSA-N 50001898 1-Phenyl-piperazine::CHEMBL9434::PHENYLPIPERAZINE D(2) dopamine receptor Rattus norvegicus 6800 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001898&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search VU9 7FMY 7096 103916265 CHEMBL9434 ZINC00120271 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093364 COc1ccccc1N1CCN(CCNC(C)=O)CC1 InChI=1S/C15H23N3O2/c1-13(19)16-7-8-17-9-11-18(12-10-17)14-5-3-4-6-15(14)20-2/h3-6H,7-12H2,1-2H3,(H,16,19) TYRMMHGVTGJEGA-UHFFFAOYSA-N 50056036 CHEMBL104591::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-acetamide D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056036&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8240066 103952442 CHEMBL104591 ZINC53172846 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093367 COc1ccccc1N1CCN(CCNC(=O)c2ccncn2)CC1 InChI=1S/C18H23N5O2/c1-25-17-5-3-2-4-16(17)23-12-10-22(11-13-23)9-8-20-18(24)15-6-7-19-14-21-15/h2-7,14H,8-13H2,1H3,(H,20,24) JUASUUUSTHHWOL-UHFFFAOYSA-N 50056035 CHEMBL107336::Pyrimidine-4-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640987 103952441 CHEMBL107336 ZINC13760893 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093371 COc1ccccc1N1CCN(CCCOc2ccc(F)cc2)CC1 InChI=1S/C20H25FN2O2/c1-24-20-6-3-2-5-19(20)23-14-12-22(13-15-23)11-4-16-25-18-9-7-17(21)8-10-18/h2-3,5-10H,4,11-16H2,1H3 LQGLHKCHSBLXDL-UHFFFAOYSA-N 50056038 1-[3-(4-Fluoro-phenoxy)-propyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL105747 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056038&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2480939 103952444 CHEMBL105747 ZINC03363307 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093372 COc1ccccc1N1CCN(CCCC(O)c2ccc(F)cc2)CC1 InChI=1S/C21H27FN2O2/c1-26-21-7-3-2-5-19(21)24-15-13-23(14-16-24)12-4-6-20(25)17-8-10-18(22)11-9-17/h2-3,5,7-11,20,25H,4,6,12-16H2,1H3 LCZRXFYSMJIDQQ-UHFFFAOYSA-N 50056039 1-(4-Fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-ol::Anisopirol::CHEMBL104515 D(2) dopamine receptor Rattus norvegicus 3.4 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13333 103952445 CHEMBL104515 ZINC04211966 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093373 COc1ccccc1N1CCN(CCNC(=O)c2ccc(F)cc2)CC1 InChI=1S/C20H24FN3O2/c1-26-19-5-3-2-4-18(19)24-14-12-23(13-15-24)11-10-22-20(25)16-6-8-17(21)9-7-16/h2-9H,10-15H2,1H3,(H,22,25) GTATVXRFYOQYFS-UHFFFAOYSA-N 50019960 4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL58377 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13318472 103930883 CHEMBL58377 ZINC52969696 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093381 Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)c1ccccc1 InChI=1S/C19H22FN3O/c20-17-8-6-16(7-9-17)19(24)21-10-11-22-12-14-23(15-13-22)18-4-2-1-3-5-18/h1-9H,10-15H2,(H,21,24) FWFUQMYEGCASTF-UHFFFAOYSA-N 50056037 4-Fluoro-N-[2-(4-phenyl-piperazin-1-yl)-ethyl]-benzamide::CHEMBL104578 D(2) dopamine receptor Rattus norvegicus 92 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056037&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 42266164 103952443 CHEMBL104578 ZINC53172833 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093386 COc1ccccc1N1CCN(CCNC(=S)C2CCCCC2)CC1 InChI=1S/C20H31N3OS/c1-24-19-10-6-5-9-18(19)23-15-13-22(14-16-23)12-11-21-20(25)17-7-3-2-4-8-17/h5-6,9-10,17H,2-4,7-8,11-16H2,1H3,(H,21,25) MYBOXBVEOOITSF-UHFFFAOYSA-N 50056040 CHEMBL107141::Cyclohexanecarbothioic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide D(2) dopamine receptor Rattus norvegicus 6.4 ChEMBL 10.1021/jm960496o 10.7270/Q27W6B96 9022796 Kuipers, W; Kruse, CG; van Wijngaarden, I; Standaar, PJ; Tulp, MT; Veldman, N; Spek, AL; IJzerman, AP Solvay Pharma http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056040&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10784832 103952446 CHEMBL107141 ZINC13760894 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093851 Cc1sc2nc(SCCCN3CCN(CC3)c3ncccn3)n(N)c(=O)c2c1C InChI=1S/C19H25N7OS2/c1-13-14(2)29-16-15(13)17(27)26(20)19(23-16)28-12-4-7-24-8-10-25(11-9-24)18-21-5-3-6-22-18/h3,5-6H,4,7-12,20H2,1-2H3 FBVVCNRRXMQYPZ-UHFFFAOYSA-N 50056362 3-Amino-5,6-dimethyl-2-[3-(4-pyrimidin-2-yl-piperazin-1-yl)-propylsulfanyl]-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL12177 D(2) dopamine receptor Rattus norvegicus 2000 ChEMBL 10.1021/jm950866t 10.7270/Q2K64H6C 9046348 Modica, M; Santagati, M; Russo, F; Parotti, L; De Gioia, L; Selvaggini, C; Salmona, M; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056362&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44267790 103952634 CHEMBL12177 ZINC12356289 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093887 COc1ccccc1C1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1 InChI=1S/C23H30N4O2S2/c1-15-16(2)31-21-20(15)22(28)27(24)23(25-21)30-14-6-11-26-12-9-17(10-13-26)18-7-4-5-8-19(18)29-3/h4-5,7-8,17H,6,9-14,24H2,1-3H3 YMNMPQRISIFNCA-UHFFFAOYSA-N 50056368 3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperidin-1-yl]-propylsulfanyl}-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL154787 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm950866t 10.7270/Q2K64H6C 9046348 Modica, M; Santagati, M; Russo, F; Parotti, L; De Gioia, L; Selvaggini, C; Salmona, M; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056368&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10504100 103952640 CHEMBL154787 ZINC27651441 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50093897 COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2N)CC1 InChI=1S/C22H29N5O2S2/c1-15-16(2)31-20-19(15)21(28)27(23)22(24-20)30-14-6-9-25-10-12-26(13-11-25)17-7-4-5-8-18(17)29-3/h4-5,7-8H,6,9-14,23H2,1-3H3 ZDQFLGSBTLYBIX-UHFFFAOYSA-N 50056378 3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propylsulfanyl}-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL12028 D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1021/jm950866t 10.7270/Q2K64H6C 9046348 Modica, M; Santagati, M; Russo, F; Parotti, L; De Gioia, L; Selvaggini, C; Salmona, M; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9981671 103952650 CHEMBL12028 ZINC13761033 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092953 C1C[C@H](CC[C@H]1N1CCN(CC1)c1ccccn1)c1c[nH]c2ccccc12 InChI=1S/C23H28N4/c1-2-6-22-20(5-1)21(17-25-22)18-8-10-19(11-9-18)26-13-15-27(16-14-26)23-7-3-4-12-24-23/h1-7,12,17-19,25H,8-11,13-16H2/t18-,19+ SYZHMHDRCWEOQG-KDURUIRLSA-N 50055718 3-[4-(4-Pyridin-2-yl-piperazin-1-yl)-cyclohexyl]-1H-indole::CHEMBL90673 D(2) dopamine receptor Rattus norvegicus 2596 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055718&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618532 103952200 CHEMBL90673 ZINC13760884 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092954 Oc1ccc2[nH]cc([C@H]3CC[C@H](CCN4CCN(CC4)c4ccccn4)CC3)c2c1 InChI=1S/C25H32N4O/c30-21-8-9-24-22(17-21)23(18-27-24)20-6-4-19(5-7-20)10-12-28-13-15-29(16-14-28)25-3-1-2-11-26-25/h1-3,8-9,11,17-20,27,30H,4-7,10,12-16H2/t19-,20- GQXBPSLBHRQMDR-MXVIHJGJSA-N 50055719 3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-1H-indol-5-ol::CHEMBL313095 D(2) dopamine receptor Rattus norvegicus 8.6 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055719&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795534 103952201 CHEMBL313095 ZINC13760890 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092955 C([C@H]1CC[C@H](CC1)c1c[nH]c2ccccc12)N1CCN(CC1)c1ccccn1 InChI=1S/C24H30N4/c1-2-6-23-21(5-1)22(17-26-23)20-10-8-19(9-11-20)18-27-13-15-28(16-14-27)24-7-3-4-12-25-24/h1-7,12,17,19-20,26H,8-11,13-16,18H2/t19-,20+ WYVYDCVFEZZZCK-BGYRXZFFSA-N 50055720 3-[4-(4-Pyridin-2-yl-piperazin-1-ylmethyl)-cyclohexyl]-1H-indole::CHEMBL84851 D(2) dopamine receptor Rattus norvegicus 122 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055720&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10667151 103952202 CHEMBL84851 ZINC13760885 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092957 C(CN1CCN(CC1)c1ncccn1)[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12 InChI=1S/C24H31N5/c1-2-5-23-21(4-1)22(18-27-23)20-8-6-19(7-9-20)10-13-28-14-16-29(17-15-28)24-25-11-3-12-26-24/h1-5,11-12,18-20,27H,6-10,13-17H2/t19-,20- NHQJFVWHLAYQQH-MXVIHJGJSA-N 50055722 3-{4-[2-(4-Pyrimidin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL87924 D(2) dopamine receptor Rattus norvegicus 161 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055722&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11794715 103952204 CHEMBL87924 ZINC00605153 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092958 C([C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12)N1CCN(CC1)c1ccccn1 InChI=1S/C24H30N4/c1-2-6-23-21(5-1)22(17-26-23)20-10-8-19(9-11-20)18-27-13-15-28(16-14-27)24-7-3-4-12-25-24/h1-7,12,17,19-20,26H,8-11,13-16,18H2/t19-,20- WYVYDCVFEZZZCK-MXVIHJGJSA-N 50055723 3-[4-(4-Pyridin-2-yl-piperazin-1-ylmethyl)-cyclohexyl]-1H-indole::CHEMBL87504 D(2) dopamine receptor Rattus norvegicus 85 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055723&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10667151 103952205 CHEMBL87504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092960 C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1 MQHGACGPMGUHSJ-HXUWFJFHSA-N 50055724 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyridin-2-yl-piperazine::CHEMBL418937::PD-137789 D(2) dopamine receptor Rattus norvegicus 412.0 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10904165 103952206 CHEMBL418937 ZINC26575034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092961 C(CN1CCC(=CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12 InChI=1S/C27H32N2/c1-2-6-22(7-3-1)23-15-18-29(19-16-23)17-14-21-10-12-24(13-11-21)26-20-28-27-9-5-4-8-25(26)27/h1-9,15,20-21,24,28H,10-14,16-19H2/t21-,24- VSQWONPJPLALKE-SAIGFBBZSA-N 50055725 3-{4-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL86662 D(2) dopamine receptor Rattus norvegicus 8.7 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055725&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620067 103952207 CHEMBL86662 ZINC01482802 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092962 C1C[C@@H](CC[C@H]1N1CCN(CC1)c1ccccn1)c1c[nH]c2ccccc12 InChI=1S/C23H28N4/c1-2-6-22-20(5-1)21(17-25-22)18-8-10-19(11-9-18)26-13-15-27(16-14-26)23-7-3-4-12-24-23/h1-7,12,17-19,25H,8-11,13-16H2/t18-,19- SYZHMHDRCWEOQG-WGSAOQKQSA-N 50055726 3-[4-(4-Pyridin-2-yl-piperazin-1-yl)-cyclohexyl]-1H-indole::CHEMBL86517 D(2) dopamine receptor Rattus norvegicus 457 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618532 103952208 CHEMBL86517 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092963 COc1ccc2[nH]cc([C@H]3CC[C@H](CCN4CCN(CC4)c4ccccn4)CC3)c2c1 InChI=1S/C26H34N4O/c1-31-22-9-10-25-23(18-22)24(19-28-25)21-7-5-20(6-8-21)11-13-29-14-16-30(17-15-29)26-4-2-3-12-27-26/h2-4,9-10,12,18-21,28H,5-8,11,13-17H2,1H3/t20-,21- YFHRSRHMFPVJQU-MEMLXQNLSA-N 50055727 5-Methoxy-3-{4-[2-(4-pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL554027 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055727&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10788182 103952209 CHEMBL554027 ZINC13760889 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092964 Cn1cc([C@H]2CC[C@H](CCN3CCN(CC3)c3ccccn3)CC2)c2ccccc12 InChI=1S/C26H34N4/c1-28-20-24(23-6-2-3-7-25(23)28)22-11-9-21(10-12-22)13-15-29-16-18-30(19-17-29)26-8-4-5-14-27-26/h2-8,14,20-22H,9-13,15-19H2,1H3/t21-,22- LACILEXWDGRNHN-HZCBDIJESA-N 50055728 1-Methyl-3-{4-[2-(4-pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL314987 D(2) dopamine receptor Rattus norvegicus 83 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055728&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692505 103952210 CHEMBL314987 ZINC13760891 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092966 C(CN1CCN(CC1)c1ccccc1)[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12 InChI=1S/C26H33N3/c1-2-6-23(7-3-1)29-18-16-28(17-19-29)15-14-21-10-12-22(13-11-21)25-20-27-26-9-5-4-8-24(25)26/h1-9,20-22,27H,10-19H2/t21-,22- NALJRHHJWWRDEP-HZCBDIJESA-N 50055729 3-{4-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL314888 D(2) dopamine receptor Rattus norvegicus 124 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055729&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10667957 103952211 CHEMBL314888 ZINC13760886 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092967 C(CN1CCC(=CC1)c1cccs1)[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12 InChI=1S/C25H30N2S/c1-2-5-24-22(4-1)23(18-26-24)20-9-7-19(8-10-20)11-14-27-15-12-21(13-16-27)25-6-3-17-28-25/h1-6,12,17-20,26H,7-11,13-16H2/t19-,20- LNRNEKDKLOZZSJ-MXVIHJGJSA-N 50055730 3-{4-[2-(4-Thiophen-2-yl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL86887 D(2) dopamine receptor Rattus norvegicus 630 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055730&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10834274 103952212 CHEMBL86887 ZINC00605154 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092968 C(CN1CCC(=CC1)c1ccccc1)[C@H]1CC[C@H](CC1)c1c[nH]c2ccccc12 InChI=1S/C27H32N2/c1-2-6-22(7-3-1)23-15-18-29(19-16-23)17-14-21-10-12-24(13-11-21)26-20-28-27-9-5-4-8-25(26)27/h1-9,15,20-21,24,28H,10-14,16-19H2/t21-,24+ VSQWONPJPLALKE-PEPAQOBHSA-N 50055731 3-{4-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL87003 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055731&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620067 103952213 CHEMBL87003 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092969 Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 HGEYJZMMUGWEOT-UHFFFAOYSA-N 50002173 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 219050 103916479 48558 CHEMBL431367 52 ZINC01548439 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092970 C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@H](CC1)c1c[nH]c2ccccc12 InChI=1S/C25H32N4/c1-2-6-24-22(5-1)23(19-27-24)21-10-8-20(9-11-21)12-14-28-15-17-29(18-16-28)25-7-3-4-13-26-25/h1-7,13,19-21,27H,8-12,14-18H2/t20-,21+ WKRNNVUISXJKDT-OYRHEFFESA-N 50055733 3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL86801 D(2) dopamine receptor Rattus norvegicus 139 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055733&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9886609 103952215 CHEMBL86801 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092971 C(CN1CCN(CC1)c1ccccn1)[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12 InChI=1S/C25H32N4/c1-2-6-24-22(5-1)23(19-27-24)21-10-8-20(9-11-21)12-14-28-15-17-29(18-16-28)25-7-3-4-13-26-25/h1-7,13,19-21,27H,8-12,14-18H2/t20-,21- WKRNNVUISXJKDT-MEMLXQNLSA-N 50055721 3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL423499 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9886609 103952203 CHEMBL423499 ZINC26575180 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092972 Fc1ccc(cc1)N1CCN(CC[C@H]2CC[C@@H](CC2)c2c[nH]c3ccccc23)CC1 InChI=1S/C26H32FN3/c27-22-9-11-23(12-10-22)30-17-15-29(16-18-30)14-13-20-5-7-21(8-6-20)25-19-28-26-4-2-1-3-24(25)26/h1-4,9-12,19-21,28H,5-8,13-18H2/t20-,21- YWTJNSVGZBZMGU-MEMLXQNLSA-N 50055732 3-(4-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-cyclohexyl)-1H-indole::CHEMBL315655 D(2) dopamine receptor Rattus norvegicus 645 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055732&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10716273 103952214 CHEMBL315655 ZINC13760887 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092973 Fc1ccc2[nH]cc([C@H]3CC[C@H](CCN4CCN(CC4)c4ccccn4)CC3)c2c1 InChI=1S/C25H31FN4/c26-21-8-9-24-22(17-21)23(18-28-24)20-6-4-19(5-7-20)10-12-29-13-15-30(16-14-29)25-3-1-2-11-27-25/h1-3,8-9,11,17-20,28H,4-7,10,12-16H2/t19-,20- IFACRBHSWWBVIG-MXVIHJGJSA-N 50055734 5-Fluoro-3-{4-[2-(4-pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-1H-indole::CHEMBL85018 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645036 103952216 CHEMBL85018 ZINC13760888 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50092974 C(CN1CCN(CC1)c1ccccn1)C1CCC(=CC1)c1c[nH]c2ccccc12 InChI=1S/C25H30N4/c1-2-6-24-22(5-1)23(19-27-24)21-10-8-20(9-11-21)12-14-28-15-17-29(18-16-28)25-7-3-4-13-26-25/h1-7,10,13,19-20,27H,8-9,11-12,14-18H2 BGGRCSFPGZVYNU-UHFFFAOYSA-N 50055735 3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohex-1-enyl}-1H-indole::CHEMBL87481 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm960597m 10.7270/Q28W3CD4 9003524 Wustrow, DJ; Smith, WJ; Corbin, AE; Davis, MD; Georgic, LM; Pugsley, TA; Whetzel, SZ; Heffner, TG; Wise, LD Division of Warner Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10762759 103952217 CHEMBL87481 ZINC26575454 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50104235 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 330 ChEMBL 10.1021/jm9704457 10.7270/Q2DV1J1D 9406603 Liao, Y; DeBoer, P; Meier, E; Wikstrom, H University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50104246 CN1CCN(CC1)C1=Nc2cc(OS(=O)(=O)C(F)(F)F)ccc2Nc2ccccc12 InChI=1S/C19H19F3N4O3S/c1-25-8-10-26(11-9-25)18-14-4-2-3-5-15(14)23-16-7-6-13(12-17(16)24-18)29-30(27,28)19(20,21)22/h2-7,12,23H,8-11H2,1H3 RDPIPNDQCUEYHW-UHFFFAOYSA-N 50061560 CHEMBL310712::Trifluoro-methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-yl ester D(2) dopamine receptor Rattus norvegicus 8100 ChEMBL 10.1021/jm9704457 10.7270/Q2DV1J1D 9406603 Liao, Y; DeBoer, P; Meier, E; Wikstrom, H University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10575100 103957122 CHEMBL310712 ZINC36238019 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50104251 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(O)cc12 InChI=1S/C18H20N4O/c1-21-8-10-22(11-9-21)18-14-12-13(23)6-7-15(14)19-16-4-2-3-5-17(16)20-18/h2-7,12,19,23H,8-11H2,1H3 KBSRARKSRVWNEC-UHFFFAOYSA-N 50061556 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-ol::CHEMBL308090 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm9704457 10.7270/Q2DV1J1D 9406603 Liao, Y; DeBoer, P; Meier, E; Wikstrom, H University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10828627 103957118 CHEMBL308090 ZINC13775874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50104254 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C19H19F3N4O3S/c1-25-8-10-26(11-9-25)18-14-12-13(29-30(27,28)19(20,21)22)6-7-15(14)23-16-4-2-3-5-17(16)24-18/h2-7,12,23H,8-11H2,1H3 XKXPMSXRABANAG-UHFFFAOYSA-N 50061559 CHEMBL72292::Trifluoro-methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-yl ester D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm9704457 10.7270/Q2DV1J1D 9406603 Liao, Y; DeBoer, P; Meier, E; Wikstrom, H University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9954899 103957121 CHEMBL72292 ZINC14299681 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50104257 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm9704457 10.7270/Q2DV1J1D 9406603 Liao, Y; DeBoer, P; Meier, E; Wikstrom, H University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50104271 COc1ccc2Nc3ccccc3N=C(N3CCN(C)CC3)c2c1 InChI=1S/C19H22N4O/c1-22-9-11-23(12-10-22)19-15-13-14(24-2)7-8-16(15)20-17-5-3-4-6-18(17)21-19/h3-8,13,20H,9-12H2,1-2H3 NXWRIBLQJIVCRL-UHFFFAOYSA-N 50061558 2-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL72794 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1021/jm9704457 10.7270/Q2DV1J1D 9406603 Liao, Y; DeBoer, P; Meier, E; Wikstrom, H University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15521599 103957120 CHEMBL72794 ZINC13775872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50104281 COc1ccc2Nc3ccccc3C(=Nc2c1)N1CCN(C)CC1 InChI=1S/C19H22N4O/c1-22-9-11-23(12-10-22)19-15-5-3-4-6-16(15)20-17-8-7-14(24-2)13-18(17)21-19/h3-8,13,20H,9-12H2,1-2H3 VTMVQXBSLJXPIT-UHFFFAOYSA-N 50061555 8-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL73074 D(2) dopamine receptor Rattus norvegicus 4300 ChEMBL 10.1021/jm9704457 10.7270/Q2DV1J1D 9406603 Liao, Y; DeBoer, P; Meier, E; Wikstrom, H University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061555&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15521598 103957117 CHEMBL73074 ZINC53150568 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50104282 CN1CCN(CC1)C1=Nc2cc(O)ccc2Nc2ccccc12 InChI=1S/C18H20N4O/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-15(14)19-16-7-6-13(23)12-17(16)20-18/h2-7,12,19,23H,8-11H2,1H3 JLYQCLIQUFEFFL-UHFFFAOYSA-N 50061557 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-ol::CHEMBL70377 D(2) dopamine receptor Rattus norvegicus 6400 ChEMBL 10.1021/jm9704457 10.7270/Q2DV1J1D 9406603 Liao, Y; DeBoer, P; Meier, E; Wikstrom, H University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 475251 103957119 CHEMBL70377 ZINC13775875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50104284 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 7.5 ChEMBL 10.1021/jm9704457 10.7270/Q2DV1J1D 9406603 Liao, Y; DeBoer, P; Meier, E; Wikstrom, H University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50109500 C(N1CCC2(CC1)CCc1ccccc1S2)c1ccccc1 InChI=1S/C20H23NS/c1-2-6-17(7-3-1)16-21-14-12-20(13-15-21)11-10-18-8-4-5-9-19(18)22-20/h1-9H,10-16H2 FPSFVONLLBIZFK-UHFFFAOYSA-N 50064172 1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydro-2'H-thiochromene)]::CHEMBL39900::SPIPETHIANE D(2) dopamine receptor Rattus norvegicus 10400 ChEMBL 10.1021/jm970740r 10.7270/Q2N29W3Q 9572880 Quaglia, W; Giannella, M; Piergentili, A; Pigini, M; Brasili, L; Di Toro, R; Rossetti, L; Spampinato, S; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10380647 103959238 CHEMBL39900 ZINC13779396 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50109501 C(N1CCC2(CC1)CCc1ccccc1O2)c1ccccc1 InChI=1S/C20H23NO/c1-2-6-17(7-3-1)16-21-14-12-20(13-15-21)11-10-18-8-4-5-9-19(18)22-20/h1-9H,10-16H2 CRKWADRIYCMTBU-UHFFFAOYSA-N 50064171 1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]::1'-benzylspiro[chroman-2,4'-piperidine]::CHEMBL38634 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970740r 10.7270/Q2N29W3Q 9572880 Quaglia, W; Giannella, M; Piergentili, A; Pigini, M; Brasili, L; Di Toro, R; Rossetti, L; Spampinato, S; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10661409 103959237 CHEMBL38634 ZINC13779400 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50017010 CCCN1CCc2nn3ccccc3c2C1 InChI=1S/C13H17N3/c1-2-7-15-9-6-12-11(10-15)13-5-3-4-8-16(13)14-12/h3-5,8H,2,6-7,9-10H2,1H3 URWBDIMBZFWGSF-UHFFFAOYSA-N 50116765 3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene::CHEMBL80845 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116765&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44316315 104010404 CHEMBL80845 ZINC12355903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50211107 CCCN[C@H]1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1 FASDKYOPVNHBLU-ZETCQYMHSA-N 50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 119570 104010405 8356 CHEMBL301265 DB00413 ZINC03781664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50211117 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50211123 CCCN(CCC)[C@H]1CCc2nn3ccccc3c2C1 InChI=1S/C17H25N3/c1-3-10-19(11-4-2)14-8-9-16-15(13-14)17-7-5-6-12-20(17)18-16/h5-7,12,14H,3-4,8-11,13H2,1-2H3/t14-/m0/s1 PWWITWFCENNJEP-AWEZNQCLSA-N 50116767 CHEMBL310867::Dipropyl-(S)-1,2,3,4-tetrahydro-pyrido[1,2-b]indazol-2-yl-amine D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116767&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10084583 104010406 CHEMBL310867 ZINC13817114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50109542 O=C1c2ccccc2CCC11CCN(Cc2ccccc2)CC1 InChI=1S/C21H23NO/c23-20-19-9-5-4-8-18(19)10-11-21(20)12-14-22(15-13-21)16-17-6-2-1-3-7-17/h1-9H,10-16H2 PZWPPSAANHYITK-UHFFFAOYSA-N 50036764 1'-benzylspiro[1,2,3,4-tetrahydronaphthalene-2,4'-(hexahydropyridine)]-1-one; hydrochloride::CHEMBL41830::CHEMBL554874 D(2) dopamine receptor Rattus norvegicus 5500 ChEMBL 10.1021/jm970740r 10.7270/Q2N29W3Q 9572880 Quaglia, W; Giannella, M; Piergentili, A; Pigini, M; Brasili, L; Di Toro, R; Rossetti, L; Spampinato, S; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9839491 103944405 CHEMBL554874CHEMBL41830 ZINC12356082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50109548 O=S1c2ccccc2CCC11CCN(Cc2ccccc2)CC1 InChI=1S/C20H23NOS/c22-23-19-9-5-4-8-18(19)10-11-20(23)12-14-21(15-13-20)16-17-6-2-1-3-7-17/h1-9H,10-16H2 QZTBMIWQKQVGNL-UHFFFAOYSA-N 50064175 1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydro-2'-sulphoxidochromene)]::CHEMBL38085 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970740r 10.7270/Q2N29W3Q 9572880 Quaglia, W; Giannella, M; Piergentili, A; Pigini, M; Brasili, L; Di Toro, R; Rossetti, L; Spampinato, S; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064175&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10782325 103959241 CHEMBL38085 ZINC13779398 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50109549 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm970740r 10.7270/Q2N29W3Q 9572880 Quaglia, W; Giannella, M; Piergentili, A; Pigini, M; Brasili, L; Di Toro, R; Rossetti, L; Spampinato, S; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50109550 O=S1(=O)c2ccccc2CCC11CCN(Cc2ccccc2)CC1 InChI=1S/C20H23NO2S/c22-24(23)19-9-5-4-8-18(19)10-11-20(24)12-14-21(15-13-20)16-17-6-2-1-3-7-17/h1-9H,10-16H2 UONOFUIISFOZLQ-UHFFFAOYSA-N 50064173 1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydro-2'-sulphurdioxochromene)]::CHEMBL38904 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970740r 10.7270/Q2N29W3Q 9572880 Quaglia, W; Giannella, M; Piergentili, A; Pigini, M; Brasili, L; Di Toro, R; Rossetti, L; Spampinato, S; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10521200 103959239 CHEMBL38904 ZINC13779399 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50111683 COc1ccc(C[C@H]2NCCc3cc(O)c(OC)cc23)cc1 InChI=1S/C18H21NO3/c1-21-14-5-3-12(4-6-14)9-16-15-11-18(22-2)17(20)10-13(15)7-8-19-16/h3-6,10-11,16,19-20H,7-9H2,1-2H3/t16-/m1/s1 HIMHLENXDBHLCU-MRXNPFEDSA-N 50259928 (R)-(+)-1-(4'-methoxybenzyl)-6-hydroxy-7-methoxy-1,2,3,4-tetrahydroisoquinoline::CHEMBL512542 D(2) dopamine receptor Rattus norvegicus 5000 ChEMBL 10.1021/np980008a 10.7270/Q29G5MJR 9644051 Cabedo, N; Protais, P; Cassels, BK; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259928&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7055406 104109932 CHEMBL512542 ZINC03847479 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50111684 COc1cc2CCN[C@H](Cc3ccc(O)cc3)c2cc1O InChI=1S/C17H19NO3/c1-21-17-9-12-6-7-18-15(14(12)10-16(17)20)8-11-2-4-13(19)5-3-11/h2-5,9-10,15,18-20H,6-8H2,1H3/t15-/m1/s1 LVVKXRQZSRUVPY-OAHLLOKOSA-N 50241488 (+)-Coclaurine::(1R)-1-(4-hydroxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinolin-7-ol::(R)-coclaurine::CHEMBL256448::d-Coclaurine D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/np980008a 10.7270/Q29G5MJR 9644051 Cabedo, N; Protais, P; Cassels, BK; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 440989 104098787 27482 CHEMBL256448 C06349 ZINC00896042 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112803 Fc1cc(OCCNCCCCc2ccc3OCCc3c2)c2OCCC(=O)c2c1 InChI=1S/C23H26FNO4/c24-18-14-19-20(26)7-11-29-23(19)22(15-18)28-12-9-25-8-2-1-3-16-4-5-21-17(13-16)6-10-27-21/h4-5,13-15,25H,1-3,6-12H2 UXLVLTZLAFGJFA-UHFFFAOYSA-N 50065558 8-{2-[4-(2,3-Dihydro-benzofuran-5-yl)-butylamino]-ethoxy}-6-fluoro-chroman-4-one::CHEMBL318417 D(2) dopamine receptor Rattus norvegicus 49.6 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10810949 103960438 CHEMBL318417 ZINC13780403 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112806 COc1ccc(CCNCCOc2cc(F)cc3CCC(C)Oc23)cc1 InChI=1S/C21H26FNO3/c1-15-3-6-17-13-18(22)14-20(21(17)26-15)25-12-11-23-10-9-16-4-7-19(24-2)8-5-16/h4-5,7-8,13-15,23H,3,6,9-12H2,1-2H3 GUSXECGCYPXWGE-UHFFFAOYSA-N 50065555 CHEMBL96578::[2-(6-Fluoro-2-methyl-chroman-8-yloxy)-ethyl]-[2-(4-methoxy-phenyl)-ethyl]-amine D(2) dopamine receptor Rattus norvegicus 8.13 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065555&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10760924 103960435 CHEMBL96578 ZINC03807435 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112807 CSc1ccc(CCCCNCCOc2cc(F)cc3C(=O)CCOc23)cc1 InChI=1S/C22H26FNO3S/c1-28-18-7-5-16(6-8-18)4-2-3-10-24-11-13-26-21-15-17(23)14-19-20(25)9-12-27-22(19)21/h5-8,14-15,24H,2-4,9-13H2,1H3 CTWLOCUPOIZLHP-UHFFFAOYSA-N 50065556 6-Fluoro-8-{2-[4-(4-methylsulfanyl-phenyl)-butylamino]-ethoxy}-chroman-4-one::CHEMBL96266 D(2) dopamine receptor Rattus norvegicus 38.8 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10644862 103960436 CHEMBL96266 ZINC13780398 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112808 Fc1cc(OCCNCCCCc2ccc3OCOc3c2)c2OCCC(=O)c2c1 InChI=1S/C22H24FNO5/c23-16-12-17-18(25)6-9-27-22(17)21(13-16)26-10-8-24-7-2-1-3-15-4-5-19-20(11-15)29-14-28-19/h4-5,11-13,24H,1-3,6-10,14H2 ORAMRCVMCRAGJE-UHFFFAOYSA-N 50065557 8-[2-(4-Benzo[1,3]dioxol-5-yl-butylamino)-ethoxy]-6-fluoro-chroman-4-one::CHEMBL94317 D(2) dopamine receptor Rattus norvegicus 42.1 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9930897 103960437 CHEMBL94317 ZINC01541478 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112812 COc1ccc(CCCCCNCCOc2cc(F)cc3CCC(C)Oc23)cc1 InChI=1S/C24H32FNO3/c1-18-7-10-20-16-21(25)17-23(24(20)29-18)28-15-14-26-13-5-3-4-6-19-8-11-22(27-2)12-9-19/h8-9,11-12,16-18,26H,3-7,10,13-15H2,1-2H3 UBWLZYQXDRBUDO-UHFFFAOYSA-N 50065560 CHEMBL95044::[2-(6-Fluoro-2-methyl-chroman-8-yloxy)-ethyl]-[5-(4-methoxy-phenyl)-pentyl]-amine D(2) dopamine receptor Rattus norvegicus 3.02 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10573128 103960440 CHEMBL95044 ZINC13780388 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112813 CN(C)c1ccc(CCCCNCCOc2cc(F)cc3C(=O)CCOc23)cc1 InChI=1S/C23H29FN2O3/c1-26(2)19-8-6-17(7-9-19)5-3-4-11-25-12-14-28-22-16-18(24)15-20-21(27)10-13-29-23(20)22/h6-9,15-16,25H,3-5,10-14H2,1-2H3 NCMSNHOGNPLCRC-UHFFFAOYSA-N 50065559 8-{2-[4-(4-Dimethylamino-phenyl)-butylamino]-ethoxy}-6-fluoro-chroman-4-one::CHEMBL94957 D(2) dopamine receptor Rattus norvegicus 34.6 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10525032 103960439 CHEMBL94957 ZINC13780399 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112815 COc1ccc(CCCCNCCOc2cc(F)cc3CCC(C)(C)Oc23)cc1 InChI=1S/C24H32FNO3/c1-24(2)12-11-19-16-20(25)17-22(23(19)29-24)28-15-14-26-13-5-4-6-18-7-9-21(27-3)10-8-18/h7-10,16-17,26H,4-6,11-15H2,1-3H3 LXKQQGFVXIEZTH-UHFFFAOYSA-N 50065562 CHEMBL96279::[2-(6-Fluoro-2,2-dimethyl-chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 0.149 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10739820 103960442 CHEMBL96279 ZINC13780379 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112816 COc1ccc(CCCCNCCOc2cc(F)cc3CCCOc23)cc1 InChI=1S/C22H28FNO3/c1-25-20-9-7-17(8-10-20)5-2-3-11-24-12-14-26-21-16-19(23)15-18-6-4-13-27-22(18)21/h7-10,15-16,24H,2-6,11-14H2,1H3 ZRVOLZXRGXGYEH-UHFFFAOYSA-N 50057436 CHEMBL25213::[2-(6-Fluoro-chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 0.259 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11740080 103953488 CHEMBL25213 ZINC13761777 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112823 COc1ccc(CCCCNCCOc2cc(F)cc3C(=O)CCOc23)cc1 InChI=1S/C22H26FNO4/c1-26-18-7-5-16(6-8-18)4-2-3-10-24-11-13-27-21-15-17(23)14-19-20(25)9-12-28-22(19)21/h5-8,14-15,24H,2-4,9-13H2,1H3 NZLGLBUAUMORQC-UHFFFAOYSA-N 50065568 6-Fluoro-8-{2-[4-(4-methoxy-phenyl)-butylamino]-ethoxy}-chroman-4-one::CHEMBL93030 D(2) dopamine receptor Rattus norvegicus 62.3 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952195 103960448 CHEMBL93030 ZINC13780380 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112832 COc1ccc(CCCCNCCOc2cc(F)cc3CCC(C)Oc23)cc1 InChI=1S/C23H30FNO3/c1-17-6-9-19-15-20(24)16-22(23(19)28-17)27-14-13-25-12-4-3-5-18-7-10-21(26-2)11-8-18/h7-8,10-11,15-17,25H,3-6,9,12-14H2,1-2H3 CCRODVWJKKAJHU-UHFFFAOYSA-N 50065573 CHEMBL96222::[2-(6-Fluoro-2-methyl-chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 0.312 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10762810 103960453 CHEMBL96222 ZINC13780378 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112841 COc1ccc(CCCCCCNCCOc2cc(F)cc3CCC(C)Oc23)cc1 InChI=1S/C25H34FNO3/c1-19-8-11-21-17-22(26)18-24(25(21)30-19)29-16-15-27-14-6-4-3-5-7-20-9-12-23(28-2)13-10-20/h9-10,12-13,17-19,27H,3-8,11,14-16H2,1-2H3 QEJMOIFWEGEFLQ-UHFFFAOYSA-N 50065561 CHEMBL96546::[2-(6-Fluoro-2-methyl-chroman-8-yloxy)-ethyl]-[6-(4-methoxy-phenyl)-hexyl]-amine D(2) dopamine receptor Rattus norvegicus 2.31 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10549786 103960441 CHEMBL96546 ZINC13780390 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112843 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.59 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112845 COc1ccc(CCCCNCCOc2cc(F)cc3C(=O)CCOc23)c2ccccc12 InChI=1S/C26H28FNO4/c1-30-24-10-9-18(20-7-2-3-8-21(20)24)6-4-5-12-28-13-15-31-25-17-19(27)16-22-23(29)11-14-32-26(22)25/h2-3,7-10,16-17,28H,4-6,11-15H2,1H3 ADQOQGKIFXKTKW-UHFFFAOYSA-N 50065574 6-Fluoro-8-{2-[4-(4-methoxy-naphthalen-1-yl)-butylamino]-ethoxy}-chroman-4-one::CHEMBL317532 D(2) dopamine receptor Rattus norvegicus 153 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10670618 103960454 CHEMBL317532 ZINC13780405 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112854 COc1ccccc1CCCCNCCOc1cc(F)cc2C(=O)CCOc12 InChI=1S/C22H26FNO4/c1-26-20-8-3-2-6-16(20)7-4-5-10-24-11-13-27-21-15-17(23)14-18-19(25)9-12-28-22(18)21/h2-3,6,8,14-15,24H,4-5,7,9-13H2,1H3 KOWYTVKGFBQCPV-UHFFFAOYSA-N 50065570 6-Fluoro-8-{2-[4-(2-methoxy-phenyl)-butylamino]-ethoxy}-chroman-4-one::CHEMBL96901 D(2) dopamine receptor Rattus norvegicus 23.7 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10548260 103960450 CHEMBL96901 ZINC13780397 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112858 Oc1ccc(CCCCNCCOc2cc(F)cc3C(=O)CCOc23)cc1 InChI=1S/C21H24FNO4/c22-16-13-18-19(25)8-11-27-21(18)20(14-16)26-12-10-23-9-2-1-3-15-4-6-17(24)7-5-15/h4-7,13-14,23-24H,1-3,8-12H2 PANSEUSOFQCKJJ-UHFFFAOYSA-N 50065566 6-Fluoro-8-{2-[4-(4-hydroxy-phenyl)-butylamino]-ethoxy}-chroman-4-one::CHEMBL319575 D(2) dopamine receptor Rattus norvegicus 23.3 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10714387 103960446 CHEMBL319575 ZINC13780393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112861 Fc1cc(OCCNCCCCc2ccc3OCCOc3c2)c2OCCC(=O)c2c1 InChI=1S/C23H26FNO5/c24-17-14-18-19(26)6-9-30-23(18)22(15-17)27-10-8-25-7-2-1-3-16-4-5-20-21(13-16)29-12-11-28-20/h4-5,13-15,25H,1-3,6-12H2 BOYAFRZUOYZYEC-UHFFFAOYSA-N 50065576 8-{2-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-butylamino]-ethoxy}-6-fluoro-chroman-4-one::CHEMBL93503 D(2) dopamine receptor Rattus norvegicus 25.1 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10716748 103960456 CHEMBL93503 ZINC12356378 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112867 CCCN(CCC)[C@H]1CCc2c(F)ccc(O)c2C1 InChI=1S/C16H24FNO/c1-3-9-18(10-4-2)12-5-6-13-14(11-12)16(19)8-7-15(13)17/h7-8,12,19H,3-6,9-11H2,1-2H3/t12-/m0/s1 FNKBVTBXFLSTPB-LBPRGKRZSA-N 50013019 (S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydronaphthalen-1-ol::(S)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-UH-301::7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol::7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol ((S)-UH301)::CHEMBL22778::UH-301 D(2) dopamine receptor Rattus norvegicus 614 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122187 103925253 CHEMBL22778 61 C11698 ZINC03874895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112872 CCCN(CCCCc1ccc2OCOc2c1)CCOc1cc(F)cc2C(=O)CCOc12 InChI=1S/C25H30FNO5/c1-2-9-27(10-4-3-5-18-6-7-22-23(14-18)32-17-31-22)11-13-29-24-16-19(26)15-20-21(28)8-12-30-25(20)24/h6-7,14-16H,2-5,8-13,17H2,1H3 SHAQMXHGPVFXFV-UHFFFAOYSA-N 50065567 8-{2-[(4-Benzo[1,3]dioxol-5-yl-butyl)-propyl-amino]-ethoxy}-6-fluoro-chroman-4-one::CHEMBL316593 D(2) dopamine receptor Rattus norvegicus 1540 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10503409 103960447 CHEMBL316593 ZINC13780407 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112874 COC1CCOc2c(OCCNCCCCc3ccc(OC)cc3)cc(F)cc12 InChI=1S/C23H30FNO4/c1-26-19-8-6-17(7-9-19)5-3-4-11-25-12-14-28-22-16-18(24)15-20-21(27-2)10-13-29-23(20)22/h6-9,15-16,21,25H,3-5,10-14H2,1-2H3 HOVRYHTZACBVKI-UHFFFAOYSA-N 50065571 CHEMBL318418::[2-(6-Fluoro-4-methoxy-chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 9.07 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10739928 103960451 CHEMBL318418 ZINC13780384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112875 COc1cccc(CCCCNCCOc2cc(F)cc3C(=O)CCOc23)c1 InChI=1S/C22H26FNO4/c1-26-18-7-4-6-16(13-18)5-2-3-9-24-10-12-27-21-15-17(23)14-19-20(25)8-11-28-22(19)21/h4,6-7,13-15,24H,2-3,5,8-12H2,1H3 DAEZIAWTFXOUTK-UHFFFAOYSA-N 50065583 6-Fluoro-8-{2-[4-(3-methoxy-phenyl)-butylamino]-ethoxy}-chroman-4-one::CHEMBL94428 D(2) dopamine receptor Rattus norvegicus 111 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065583&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10762799 103960463 CHEMBL94428 ZINC13780396 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112877 COc1ccc(CCCCNCCOc2cc(F)cc3C(O)CCOc23)cc1 InChI=1S/C22H28FNO4/c1-26-18-7-5-16(6-8-18)4-2-3-10-24-11-13-27-21-15-17(23)14-19-20(25)9-12-28-22(19)21/h5-8,14-15,20,24-25H,2-4,9-13H2,1H3 GQVNYCJRZSTERX-UHFFFAOYSA-N 50065563 6-Fluoro-8-{2-[4-(4-methoxy-phenyl)-butylamino]-ethoxy}-chroman-4-ol::CHEMBL96714 D(2) dopamine receptor Rattus norvegicus 0.724 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44212473 103960443 CHEMBL96714 ZINC13780382 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112883 Fc1cc(OCCNCCCCc2ccc(cc2)C#N)c2OCCC(=O)c2c1 InChI=1S/C22H23FN2O3/c23-18-13-19-20(26)8-11-28-22(19)21(14-18)27-12-10-25-9-2-1-3-16-4-6-17(15-24)7-5-16/h4-7,13-14,25H,1-3,8-12H2 XTSRSIPANVDHSS-UHFFFAOYSA-N 50065579 4-{4-[2-(6-Fluoro-4-oxo-chroman-8-yloxy)-ethylamino]-butyl}-benzonitrile::CHEMBL96903 D(2) dopamine receptor Rattus norvegicus 70.4 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065579&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10619900 103960459 CHEMBL96903 ZINC13780401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112886 Fc1cc(OCCNCCCCc2ccccc2)c2OCCC(=O)c2c1 InChI=1S/C21H24FNO3/c22-17-14-18-19(24)9-12-26-21(18)20(15-17)25-13-11-23-10-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,14-15,23H,4-5,8-13H2 VVDDZQNEZFZTCT-UHFFFAOYSA-N 50065575 6-Fluoro-8-[2-(4-phenyl-butylamino)-ethoxy]-chroman-4-one::CHEMBL330714 D(2) dopamine receptor Rattus norvegicus 43.9 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522319 103960455 CHEMBL330714 ZINC12356181 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112887 COc1ccc(CCNCCOc2cc(F)cc3C(=O)CCOc23)cc1 InChI=1S/C20H22FNO4/c1-24-16-4-2-14(3-5-16)6-8-22-9-11-25-19-13-15(21)12-17-18(23)7-10-26-20(17)19/h2-5,12-13,22H,6-11H2,1H3 NTUCKYNKXAWPFO-UHFFFAOYSA-N 50065569 6-Fluoro-8-{2-[2-(4-methoxy-phenyl)-ethylamino]-ethoxy}-chroman-4-one::CHEMBL96435 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618448 103960449 CHEMBL96435 ZINC12356182 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112890 COc1ccc(CCCNCCOc2cc(F)cc3CCC(C)Oc23)cc1 InChI=1S/C22H28FNO3/c1-16-5-8-18-14-19(23)15-21(22(18)27-16)26-13-12-24-11-3-4-17-6-9-20(25-2)10-7-17/h6-7,9-10,14-16,24H,3-5,8,11-13H2,1-2H3 OFIAKRBYKQTIPM-UHFFFAOYSA-N 50065565 CHEMBL92651::[2-(6-Fluoro-2-methyl-chroman-8-yloxy)-ethyl]-[3-(4-methoxy-phenyl)-propyl]-amine D(2) dopamine receptor Rattus norvegicus 4.98 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10690752 103960445 CHEMBL92651 ZINC13780386 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112894 CCOc1ccc(CCCCNCCOc2cc(F)cc3C(=O)CCOc23)cc1 InChI=1S/C23H28FNO4/c1-2-27-19-8-6-17(7-9-19)5-3-4-11-25-12-14-28-22-16-18(24)15-20-21(26)10-13-29-23(20)22/h6-9,15-16,25H,2-5,10-14H2,1H3 SACUASDNQZLHAU-UHFFFAOYSA-N 50065554 8-{2-[4-(4-Ethoxy-phenyl)-butylamino]-ethoxy}-6-fluoro-chroman-4-one::CHEMBL329675 D(2) dopamine receptor Rattus norvegicus 55.1 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065554&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795325 103960434 CHEMBL329675 ZINC13780394 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112896 COc1ccc(CCCCNCCOc2cc(F)cc3C=CCOc23)cc1 InChI=1S/C22H26FNO3/c1-25-20-9-7-17(8-10-20)5-2-3-11-24-12-14-26-21-16-19(23)15-18-6-4-13-27-22(18)21/h4,6-10,15-16,24H,2-3,5,11-14H2,1H3 UKJKGQUJKWNSRT-UHFFFAOYSA-N 50065578 CHEMBL419147::[2-(6-Fluoro-2H-chromen-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 0.288 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10737977 103960458 CHEMBL419147 ZINC01541480 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112898 COc1ccc(CCNCCOc2cc(F)cc3C(O)CCOc23)cc1 InChI=1S/C20H24FNO4/c1-24-16-4-2-14(3-5-16)6-8-22-9-11-25-19-13-15(21)12-17-18(23)7-10-26-20(17)19/h2-5,12-13,18,22-23H,6-11H2,1H3 CGLIIBDLSLHMID-UHFFFAOYSA-N 50065582 6-Fluoro-8-{2-[2-(4-methoxy-phenyl)-ethylamino]-ethoxy}-chroman-4-ol::CHEMBL96517 D(2) dopamine receptor Rattus norvegicus 2.99 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065582&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618582 103960462 CHEMBL96517 ZINC13780392 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112899 Fc1cc(OCCNCCCCc2ccc(Cl)cc2)c2OCCC(=O)c2c1 InChI=1S/C21H23ClFNO3/c22-16-6-4-15(5-7-16)3-1-2-9-24-10-12-26-20-14-17(23)13-18-19(25)8-11-27-21(18)20/h4-7,13-14,24H,1-3,8-12H2 PBENURCHEWSCJC-UHFFFAOYSA-N 50065581 8-{2-[4-(4-Chloro-phenyl)-butylamino]-ethoxy}-6-fluoro-chroman-4-one::CHEMBL96265 D(2) dopamine receptor Rattus norvegicus 32.3 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10715513 103960461 CHEMBL96265 ZINC13780400 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50112904 COc1ccc(CCCCNCCOc2cc(F)cc3C(CCOc23)N=O)cc1 InChI=1S/C22H27FN2O4/c1-27-18-7-5-16(6-8-18)4-2-3-10-24-11-13-28-21-15-17(23)14-19-20(25-26)9-12-29-22(19)21/h5-8,14-15,20,24H,2-4,9-13H2,1H3 PPHVQMIPIXHSLV-UHFFFAOYSA-N 50065580 6-Fluoro-8-{2-[4-(4-methoxy-phenyl)-butylamino]-ethoxy}-chroman-4-one oxime::CHEMBL96858 D(2) dopamine receptor Rattus norvegicus 11.7 ChEMBL 10.1021/jm9707840 10.7270/Q2K073CQ 9667967 Yasunaga, T; Kimura, T; Naito, R; Kontani, T; Wanibuchi, F; Yamashita, H; Nomura, T; Tsukamoto, S; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50065580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50065580&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54201108 103960460 CHEMBL96858 ZINC13780381 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121082 CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C24H27N3O2/c1-27-14-17(12-26-24(28)29-15-16-6-3-2-4-7-16)10-20-19-8-5-9-21-23(19)18(13-25-21)11-22(20)27/h2-9,13,17,20,22,25H,10-12,14-15H2,1H3,(H,26,28)/t17-,20+,22+/m0/s1 REJFPXMKRRYBSC-UCNVEGJOSA-N 50070184 ((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-carbamic acid benzyl ester::(7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-carbamic acid benzyl ester::CHEMBL13816 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070184&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22857296 103964102 CHEMBL13816 ZINC05967023 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121085 CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C InChI=1S/C28H35N3O2/c1-28(2,3)23-11-10-21-22-12-19(14-30-27(32)33-17-18-8-6-5-7-9-18)16-31(4)24(22)13-20-15-29-26(23)25(20)21/h5-11,15,19,22,24,29H,12-14,16-17H2,1-4H3,(H,30,32)/t19-,22+,24+/m0/s1 DENVMYPRJDLGGR-BPUDTRNYSA-N 50070190 ((6aR,9S,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-carbamic acid benzyl ester::CHEMBL275873 D(2) dopamine receptor Rattus norvegicus 830.0 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070190&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269148 103964108 CHEMBL275873 ZINC34800963 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121087 CN1C[C@H](Cn2cc(O)[nH]c2=O)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C InChI=1S/C23H30N4O2/c1-23(2,3)17-6-5-15-16-7-13(11-27-12-19(28)25-22(27)29)10-26(4)18(16)8-14-9-24-21(17)20(14)15/h5-6,9,12-13,16,18,24,28H,7-8,10-11H2,1-4H3,(H,25,29)/t13-,16-,18-/m1/s1 IBVOBUKSEOTNKH-MZMPZRCHSA-N 50070191 1-((6aR,9R,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-imidazolidine-2,4-dione::CHEMBL13464 D(2) dopamine receptor Rattus norvegicus 940.0 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070191&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53908158 103964109 CHEMBL13464 ZINC34800930 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121090 C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4c(ccc2c34)C(C)(C)C)N(C)C1 InChI=1S/C20H28N2/c1-12-8-15-14-6-7-16(20(2,3)4)19-18(14)13(10-21-19)9-17(15)22(5)11-12/h6-7,10,12,15,17,21H,8-9,11H2,1-5H3/t12-,15-,17-/m1/s1 QXMSVDRZXCYHTI-SRCQZFHVSA-N 50070194 (6aR,9R,10aR)-3-tert-Butyl-7,9-dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::CHEMBL13811 D(2) dopamine receptor Rattus norvegicus 3740 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070194&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269092 103964112 CHEMBL13811 ZINC34800944 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121094 CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4c(ccc2c34)C(C)(C)C)N(C)C1 InChI=1S/C28H43N5O2/c1-8-29-27(35)33(13-9-12-31(5)6)26(34)19-14-21-20-10-11-22(28(2,3)4)25-24(20)18(16-30-25)15-23(21)32(7)17-19/h10-11,16,19,21,23,30H,8-9,12-15,17H2,1-7H3,(H,29,35)/t19-,21-,23-/m1/s1 HXGXZOPMFRVLIW-KJXAQDMKSA-N 50070188 1-((6aR,9R,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carbonyl)-1-(3-dimethylamino-propyl)-3-ethyl-urea::CHEMBL13805 D(2) dopamine receptor Rattus norvegicus 570.0 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070188&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269145 103964106 CHEMBL13805 ZINC34800956 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121095 C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 InChI=1S/C16H20N2/c1-10-6-13-12-4-3-5-14-16(12)11(8-17-14)7-15(13)18(2)9-10/h3-5,8,10,13,15,17H,6-7,9H2,1-2H3/t10-,13-,15-/m1/s1 VLMZMRDOMOGGFA-WDBKCZKBSA-N 50016489 (6aR,9R,10aR)-7,9-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::7,9-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::CHEMBL13866 D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016489&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 332915 103927887 65035 CHEMBL13866 ZINC05706407 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121101 CN1C[C@H](Cn2cc(O)[nH]c2=O)C[C@H]2[C@H]1Cc1c[nH]c3cc(cc2c13)C(C)(C)C InChI=1S/C23H30N4O2/c1-23(2,3)15-7-17-16-5-13(11-27-12-20(28)25-22(27)29)10-26(4)19(16)6-14-9-24-18(8-15)21(14)17/h7-9,12-13,16,19,24,28H,5-6,10-11H2,1-4H3,(H,25,29)/t13-,16-,19-/m1/s1 PPTOLRVWTPEUES-VVFCZOMOSA-N 50070196 1-((6aR,9R,10aR)-2-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-imidazolidine-2,4-dione::CHEMBL275539 D(2) dopamine receptor Rattus norvegicus 7630 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070196 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070196&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91930938 103964114 CHEMBL275539 ZINC34800947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121103 CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C)C(=O)Nc1nccs1 InChI=1S/C23H28N4OS/c1-23(2,3)17-6-5-15-16-9-14(21(28)26-22-24-7-8-29-22)12-27(4)18(16)10-13-11-25-20(17)19(13)15/h5-8,11,14,16,18,25H,9-10,12H2,1-4H3,(H,24,26,28)/t14-,16-,18-/m1/s1 OYWXVFDTIHNXDL-QGPMSJSTSA-N 50070198 (6aR,9R,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carboxylic acid thiazol-2-ylamide::CHEMBL276271 D(2) dopamine receptor Rattus norvegicus 1260 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070198 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070198&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269094 103964116 CHEMBL276271 ZINC34800957 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121111 CN1C[C@H](Cn2cc(O)[nH]c2=O)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H22N4O2/c1-22-8-11(9-23-10-17(24)21-19(23)25)5-14-13-3-2-4-15-18(13)12(7-20-15)6-16(14)22/h2-4,7,10-11,14,16,20,24H,5-6,8-9H2,1H3,(H,21,25)/t11-,14-,16-/m1/s1 VCFIBWJEAKOUJM-DJSGYFEHSA-N 50070199 1-((6aR,9R,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-imidazolidine-2,4-dione::CHEMBL13588 D(2) dopamine receptor Rattus norvegicus 1120 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070199&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54384404 103964117 CHEMBL13588 ZINC03791049 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121119 CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)Nc1nccs1 InChI=1S/C19H20N4OS/c1-23-10-12(18(24)22-19-20-5-6-25-19)7-14-13-3-2-4-15-17(13)11(9-21-15)8-16(14)23/h2-6,9,12,14,16,21H,7-8,10H2,1H3,(H,20,22,24)/t12-,14-,16-/m1/s1 FARIHHBFWQQJLW-XNRPHZJLSA-N 50070197 (6aR,9R,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carboxylic acid thiazol-2-ylamide::CHEMBL269160 D(2) dopamine receptor Rattus norvegicus 170 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070197&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269117 103964115 CHEMBL269160 ZINC34800951 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121121 C[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cc(cc2c34)C(C)(C)C)N(C)C1 InChI=1S/C20H28N2/c1-12-6-15-16-8-14(20(2,3)4)9-17-19(16)13(10-21-17)7-18(15)22(5)11-12/h8-10,12,15,18,21H,6-7,11H2,1-5H3/t12-,15-,18-/m1/s1 FLTZEKITQLGBQU-CDHAZOANSA-N 50070183 (6aR,9R,10aR)-2-tert-Butyl-7,9-dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::CHEMBL14138 D(2) dopamine receptor Rattus norvegicus 9130.0 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269143 103964101 CHEMBL14138 ZINC34800959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121129 CN1C[C@H](CNC(=S)NC(C)=O)C[C@H]2[C@H]1Cc1c[nH]c3cc(cc2c13)C(C)(C)C InChI=1S/C23H32N4OS/c1-13(28)26-22(29)25-10-14-6-17-18-8-16(23(2,3)4)9-19-21(18)15(11-24-19)7-20(17)27(5)12-14/h8-9,11,14,17,20,24H,6-7,10,12H2,1-5H3,(H2,25,26,28,29)/t14-,17+,20+/m0/s1 LYIXVNJIOYBMOA-JNAXZKDPSA-N 50070189 1-Acetyl-3-((6aR,9S,10aR)-2-tert-butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-thiourea::CHEMBL14238 D(2) dopamine receptor Rattus norvegicus 5470.0 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070189&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269132 103964107 CHEMBL14238 ZINC36187743 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119002 COc1cc2CCN(C)CC3CN(c(c23)c1OC)c1ccc(F)cc1 InChI=1S/C20H23FN2O2/c1-22-9-8-13-10-17(24-2)20(25-3)19-18(13)14(11-22)12-23(19)16-6-4-15(21)5-7-16/h4-7,10,14H,8-9,11-12H2,1-3H3 SMWRVQMZVOVXSA-UHFFFAOYSA-N 50069011 1-(4-Fluoro-phenyl)-8,9-dimethoxy-4-methyl-2,2a,3,4,5,6-hexahydro-1H-azepino[3,4,5-cd]indole::CHEMBL178797 D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069011&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44386836 103963157 CHEMBL178797 ZINC28108127 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119003 COc1cc2CCNCC3CN(c(c23)c1OC)c1ccc(F)cc1 InChI=1S/C19H21FN2O2/c1-23-16-9-12-7-8-21-10-13-11-22(15-5-3-14(20)4-6-15)18(17(12)13)19(16)24-2/h3-6,9,13,21H,7-8,10-11H2,1-2H3 XYNLJBRCCYTMSL-UHFFFAOYSA-N 50069012 1-(4-Fluoro-phenyl)-8,9-dimethoxy-2,2a,3,4,5,6-hexahydro-1H-azepino[3,4,5-cd]indole::CHEMBL174949 D(2) dopamine receptor Rattus norvegicus 67 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069012&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44386883 103963158 CHEMBL174949 ZINC28092892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119016 CN1CCc2cccc3n(cc(C1)c23)-c1ccc(F)cc1 InChI=1S/C18H17FN2/c1-20-10-9-13-3-2-4-17-18(13)14(11-20)12-21(17)16-7-5-15(19)6-8-16/h2-8,12H,9-11H2,1H3 IRXXYVVZUJPSPA-UHFFFAOYSA-N 50069018 1-(4-Fluoro-phenyl)-4-methyl-3,4,5,6-tetrahydro-1H-azepino[3,4,5-cd]indole::CHEMBL176476 D(2) dopamine receptor Rattus norvegicus 83 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069018&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385715 103963164 CHEMBL176476 ZINC28087653 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121155 CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C23H25N3O/c1-26-14-15(12-25-23(27)16-6-3-2-4-7-16)10-19-18-8-5-9-20-22(18)17(13-24-20)11-21(19)26/h2-9,13,15,19,21,24H,10-12,14H2,1H3,(H,25,27)/t15-,19+,21+/m0/s1 MJSUQPQBXGYQHP-NYSBEXSLSA-N 50070203 CHEMBL14048::N-((6aR,9S,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-benzamide D(2) dopamine receptor Rattus norvegicus 75.0 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070203&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10498684 103964121 CHEMBL14048 ZINC34800962 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121158 CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C InChI=1S/C27H33N3O/c1-27(2,3)22-11-10-20-21-12-17(14-29-26(31)18-8-6-5-7-9-18)16-30(4)23(21)13-19-15-28-25(22)24(19)20/h5-11,15,17,21,23,28H,12-14,16H2,1-4H3,(H,29,31)/t17-,21+,23+/m0/s1 MOWAUISIARUDCJ-AMHTUMDSSA-N 50070202 CHEMBL267799::N-((6aR,9S,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-benzamide D(2) dopamine receptor Rattus norvegicus 2070 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070202 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070202&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269146 103964120 CHEMBL267799 ZINC36187736 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121161 CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cc(cc2c13)C(C)(C)C)C(=O)Nc1nccs1 InChI=1S/C23H28N4OS/c1-23(2,3)15-9-17-16-7-14(21(28)26-22-24-5-6-29-22)12-27(4)19(16)8-13-11-25-18(10-15)20(13)17/h5-6,9-11,14,16,19,25H,7-8,12H2,1-4H3,(H,24,26,28)/t14-,16-,19-/m1/s1 ZPSZJXUFHHHORF-IDHHARJASA-N 50070182 (6aR,9R,10aR)-2-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carboxylic acid thiazol-2-ylamide::CHEMBL418717 D(2) dopamine receptor Rattus norvegicus 1120 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269120 103964100 CHEMBL418717 ZINC34800955 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121165 CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13)C(=O)Nc1ccc(Cl)nn1 InChI=1S/C20H20ClN5O/c1-26-10-12(20(27)23-18-6-5-17(21)24-25-18)7-14-13-3-2-4-15-19(13)11(9-22-15)8-16(14)26/h2-6,9,12,14,16,22H,7-8,10H2,1H3,(H,23,25,27)/t12-,14-,16-/m1/s1 WNVXZCMENBYWES-XNRPHZJLSA-N 50070195 (6aR,9R,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (6-chloro-pyridazin-3-yl)-amide::CHEMBL13979 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269131 103964113 CHEMBL13979 ZINC34800953 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121166 CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 InChI=1S/C24H35N5O2/c1-5-25-24(31)29(11-7-10-27(2)3)23(30)17-12-19-18-8-6-9-20-22(18)16(14-26-20)13-21(19)28(4)15-17/h6,8-9,14,17,19,21,26H,5,7,10-13,15H2,1-4H3,(H,25,31)/t17-,19-,21-/m1/s1 XEMCUJCVRDSIHH-YFVAEKQCSA-N 50070181 1-(3-Dimethylamino-propyl)-3-ethyl-1-((6aR,9R,10aR)-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carbonyl)-urea::CHEMBL14022 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269058 103964099 CHEMBL14022 ZINC34800941 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121177 CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C)C(=O)Nc1ccc(Cl)nn1 InChI=1S/C24H28ClN5O/c1-24(2,3)17-6-5-15-16-9-14(23(31)27-20-8-7-19(25)28-29-20)12-30(4)18(16)10-13-11-26-22(17)21(13)15/h5-8,11,14,16,18,26H,9-10,12H2,1-4H3,(H,27,29,31)/t14-,16-,18-/m1/s1 CQMXKYDRFMRPTO-QGPMSJSTSA-N 50070192 (6aR,9R,10aR)-3-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (6-chloro-pyridazin-3-yl)-amide::CHEMBL14089 D(2) dopamine receptor Rattus norvegicus 960 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070192&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269142 103964110 CHEMBL14089 ZINC34800958 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121181 CN1C[C@@H](C[C@H]2[C@H]1Cc1c[nH]c3cc(cc2c13)C(C)(C)C)C(=O)Nc1ccc(Cl)nn1 InChI=1S/C24H28ClN5O/c1-24(2,3)15-9-17-16-7-14(23(31)27-21-6-5-20(25)28-29-21)12-30(4)19(16)8-13-11-26-18(10-15)22(13)17/h5-6,9-11,14,16,19,26H,7-8,12H2,1-4H3,(H,27,29,31)/t14-,16-,19-/m1/s1 WZWOJXYVHLNKQO-IDHHARJASA-N 50070200 (6aR,9R,10aR)-2-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (6-chloro-pyridazin-3-yl)-amide::CHEMBL13770 D(2) dopamine receptor Rattus norvegicus 2620 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070200 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070200&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269075 103964118 CHEMBL13770 ZINC34800936 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121196 CN1C[C@H](CNC(=O)c2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cc(cc2c13)C(C)(C)C InChI=1S/C27H33N3O/c1-27(2,3)20-12-22-21-10-17(14-29-26(31)18-8-6-5-7-9-18)16-30(4)24(21)11-19-15-28-23(13-20)25(19)22/h5-9,12-13,15,17,21,24,28H,10-11,14,16H2,1-4H3,(H,29,31)/t17-,21+,24+/m0/s1 OJMHZETUZYJZAI-XVWGUNQUSA-N 50070185 CHEMBL273526::N-((6aR,9S,10aR)-2-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-benzamide D(2) dopamine receptor Rattus norvegicus 5170 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070185&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9979258 103964103 CHEMBL273526 ZINC34800961 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121210 CN1C[C@H](CNC(=S)NC(C)=O)C[C@H]2[C@H]1Cc1c[nH]c3c(ccc2c13)C(C)(C)C InChI=1S/C23H32N4OS/c1-13(28)26-22(29)25-10-14-8-17-16-6-7-18(23(2,3)4)21-20(16)15(11-24-21)9-19(17)27(5)12-14/h6-7,11,14,17,19,24H,8-10,12H2,1-5H3,(H2,25,26,28,29)/t14-,17+,19+/m0/s1 KUUURIADAZPOIK-POZUXBRTSA-N 50070187 1-Acetyl-3-((6aR,9S,10aR)-3-tert-butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-thiourea::CHEMBL14020 D(2) dopamine receptor Rattus norvegicus 1410 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070187&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269057 103964105 CHEMBL14020 ZINC34800939 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121213 CN1C[C@H](CNC(=S)NC(C)=O)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H24N4OS/c1-11(24)22-19(25)21-8-12-6-15-14-4-3-5-16-18(14)13(9-20-16)7-17(15)23(2)10-12/h3-5,9,12,15,17,20H,6-8,10H2,1-2H3,(H2,21,22,24,25)/t12-,15+,17+/m0/s1 VNRVWDFBQJATNK-XGWLTEMNSA-N 50070186 1-Acetyl-3-((6aR,9S,10aR)-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-thiourea::CHEMBL14239 D(2) dopamine receptor Rattus norvegicus 730 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070186&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269133 103964104 CHEMBL14239 ZINC36187744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119027 CN1CCc2cccc3NCC(C1)c23 InChI=1S/C12H16N2/c1-14-6-5-9-3-2-4-11-12(9)10(8-14)7-13-11/h2-4,10,13H,5-8H2,1H3 JJELBIARFJVXTD-UHFFFAOYSA-N 50069020 4-Methyl-2,2a,3,4,5,6-hexahydro-1H-azepino[3,4,5-cd]indole::CHEMBL366377 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385452 103963166 CHEMBL366377 ZINC28018902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119034 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.200000 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119048 CN1CCc2cc(O)c(O)c3n(cc(C1)c23)-c1ccc(F)cc1 InChI=1S/C18H17FN2O2/c1-20-7-6-11-8-15(22)18(23)17-16(11)12(9-20)10-21(17)14-4-2-13(19)3-5-14/h2-5,8,10,22-23H,6-7,9H2,1H3 IISOLZDJGFCWCP-UHFFFAOYSA-N 50069014 1-(4-Fluoro-phenyl)-4-methyl-3,4,5,6-tetrahydro-1H-azepino[3,4,5-cd]indole-8,9-diol::CHEMBL176363 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069014&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385928 103963160 CHEMBL176363 ZINC28021513 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119049 COc1cc2CCN(C)Cc3cn(-c4ccc(F)cc4)c(c1OC)c23 InChI=1S/C20H21FN2O2/c1-22-9-8-13-10-17(24-2)20(25-3)19-18(13)14(11-22)12-23(19)16-6-4-15(21)5-7-16/h4-7,10,12H,8-9,11H2,1-3H3 WZSCCMIZBBXQBU-UHFFFAOYSA-N 50069017 1-(4-Fluoro-phenyl)-8,9-dimethoxy-4-methyl-3,4,5,6-tetrahydro-1H-azepino[3,4,5-cd]indole::CHEMBL366504 D(2) dopamine receptor Rattus norvegicus 370 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069017&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44386833 103963163 CHEMBL366504 ZINC28105270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119020 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 2.1 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119054 COc1c2N(CC3CN(C)CCc(c23)c(Cl)c1OC)c1ccc(F)cc1 InChI=1S/C20H22ClFN2O2/c1-23-9-8-15-16-12(10-23)11-24(14-6-4-13(22)5-7-14)18(16)20(26-3)19(25-2)17(15)21/h4-7,12H,8-11H2,1-3H3 ZLEMKTFXPSIGOM-UHFFFAOYSA-N 50069019 7-Chloro-1-(4-fluoro-phenyl)-8,9-dimethoxy-4-methyl-2,2a,3,4,5,6-hexahydro-1H-azepino[3,4,5-cd]indole::CHEMBL176356 D(2) dopamine receptor Rattus norvegicus 6.8 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44386623 103963165 CHEMBL176356 ZINC28087642 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119058 CN1CCc2cccc3[nH]cc(C1)c23 InChI=1S/C12H14N2/c1-14-6-5-9-3-2-4-11-12(9)10(8-14)7-13-11/h2-4,7,13H,5-6,8H2,1H3 UNYZCCDZGZDKJH-UHFFFAOYSA-N 50069022 4-Methyl-3,4,5,6-tetrahydro-1H-azepino[3,4,5-cd]indole::4-Methyl-3,4,5,6-tetrahydro-1H-azepino[3,4,5-cd]indole : (Hydrobromide)::CHEMBL160430 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069022&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372305 103963168 CHEMBL160430 ZINC27720135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119060 CN1CCc2cccc3N(CC(C1)c23)c1ccc(F)cc1 InChI=1S/C18H19FN2/c1-20-10-9-13-3-2-4-17-18(13)14(11-20)12-21(17)16-7-5-15(19)6-8-16/h2-8,14H,9-12H2,1H3 SVMZEPNYJCPPQZ-UHFFFAOYSA-N 50069016 1-(4-Fluoro-phenyl)-4-methyl-2,2a,3,4,5,6-hexahydro-1H-azepino[3,4,5-cd]indole::CHEMBL173315 D(2) dopamine receptor Rattus norvegicus 9.2 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069016&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9993922 103963162 CHEMBL173315 ZINC28013878 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119062 CN1CCc2cc(O)c(O)c3N(CC(C1)c23)c1ccc(F)cc1 InChI=1S/C18H19FN2O2/c1-20-7-6-11-8-15(22)18(23)17-16(11)12(9-20)10-21(17)14-4-2-13(19)3-5-14/h2-5,8,12,22-23H,6-7,9-10H2,1H3 QGDRDWYAKNWQPW-UHFFFAOYSA-N 50069015 1-(4-Fluoro-phenyl)-4-methyl-2,2a,3,4,5,6-hexahydro-1H-azepino[3,4,5-cd]indole-8,9-diol::CHEMBL367981 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069015&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385979 103963161 CHEMBL367981 ZINC28013871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119063 CN(C)CC1CN(c2cccc(C)c12)c1ccc(F)cc1 InChI=1S/C18H21FN2/c1-13-5-4-6-17-18(13)14(11-20(2)3)12-21(17)16-9-7-15(19)8-10-16/h4-10,14H,11-12H2,1-3H3 FOPDUCMTADSUBN-UHFFFAOYSA-N 50069013 CHEMBL171903::[1-(4-Fluoro-phenyl)-4-methyl-2,3-dihydro-1H-indol-3-ylmethyl]-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069013&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385451 103963159 CHEMBL171903 ZINC28018892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119068 Fc1ccc(cc1)N1CC2CNCCc3cccc1c23 InChI=1S/C17H17FN2/c18-14-4-6-15(7-5-14)20-11-13-10-19-9-8-12-2-1-3-16(20)17(12)13/h1-7,13,19H,8-11H2 JPDOPMUPXBQWBY-UHFFFAOYSA-N 50069021 1-(4-Fluoro-phenyl)-2,2a,3,4,5,6-hexahydro-1H-azepino[3,4,5-cd]indole::CHEMBL176990 D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1016/s0960-894x(98)00138-3 10.7270/Q2Q81C7Z 9871525 Maryanoff, BE; McComsey, DF; Martin, GE; Shank, RP R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069021&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44385980 103963167 CHEMBL176990 ZINC28089311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121218 CN1C[C@H](CNC(=O)OCc2ccccc2)C[C@H]2[C@H]1Cc1c[nH]c3cc(cc2c13)C(C)(C)C InChI=1S/C28H35N3O2/c1-28(2,3)21-12-23-22-10-19(14-30-27(32)33-17-18-8-6-5-7-9-18)16-31(4)25(22)11-20-15-29-24(13-21)26(20)23/h5-9,12-13,15,19,22,25,29H,10-11,14,16-17H2,1-4H3,(H,30,32)/t19-,22+,25+/m0/s1 JIEYWGGNJSSGDF-UWUFEASWSA-N 50070201 ((6aR,9S,10aR)-2-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-ylmethyl)-carbamic acid benzyl ester::CHEMBL429051 D(2) dopamine receptor Rattus norvegicus 1250 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070201 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070201&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10765759 103964119 CHEMBL429051 ZINC34800932 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121221 CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cc(cc2c34)C(C)(C)C)N(C)C1 InChI=1S/C28H43N5O2/c1-8-29-27(35)33(11-9-10-31(5)6)26(34)19-12-21-22-14-20(28(2,3)4)15-23-25(22)18(16-30-23)13-24(21)32(7)17-19/h14-16,19,21,24,30H,8-13,17H2,1-7H3,(H,29,35)/t19-,21-,24-/m1/s1 BNMXUFDTDMYUGI-ZILOHOTNSA-N 50070193 1-((6aR,9R,10aR)-2-tert-Butyl-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline-9-carbonyl)-1-(3-dimethylamino-propyl)-3-ethyl-urea::CHEMBL276013 D(2) dopamine receptor Rattus norvegicus 1060 ChEMBL 10.1016/s0960-894x(98)00166-8 10.7270/Q2M61JF3 9871719 Mantegani, S; Brambilla, E; Caccia, C; Damiani, G; Fornaretto, MG; McArthur, RA; Varasi, M Pharmacia & Upjohn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070193&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269165 103964111 CHEMBL276013 ZINC34800960 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118210 CC(C)N1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C21H30FN3O2/c1-16(2)25-15-23(3)21(20(25)27)10-13-24(14-11-21)12-4-5-19(26)17-6-8-18(22)9-7-17/h6-9,16H,4-5,10-15H2,1-3H3 KKTPGSBDSZRGAT-UHFFFAOYSA-N 50068518 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-isopropyl-1-methyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL146591 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10738246 103962721 CHEMBL146591 ZINC13782365 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118216 CCCCN1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C22H32FN3O2/c1-3-4-14-26-17-24(2)22(21(26)28)11-15-25(16-12-22)13-5-6-20(27)18-7-9-19(23)10-8-18/h7-10H,3-6,11-17H2,1-2H3 VQOFRAUEWAFOEI-UHFFFAOYSA-N 50068517 3-Butyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1-methyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL148358 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10810380 103962720 CHEMBL148358 ZINC13782366 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118221 CCN1CNC(=O)C11CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C19H26FN3O2/c1-2-23-14-21-18(25)19(23)9-12-22(13-10-19)11-3-4-17(24)15-5-7-16(20)8-6-15/h5-8H,2-4,9-14H2,1H3,(H,21,25) YEQJFVRVXBZCEM-UHFFFAOYSA-N 50068520 1-Ethyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL342963 D(2) dopamine receptor Rattus norvegicus 170 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10689000 103962723 CHEMBL342963 ZINC13782361 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118228 CCCN1CN(C)C2(CCN(CCCOc3ccc(F)cc3)CC2)C1=O InChI=1S/C20H30FN3O2/c1-3-11-24-16-22(2)20(19(24)25)9-13-23(14-10-20)12-4-15-26-18-7-5-17(21)6-8-18/h5-8H,3-4,9-16H2,1-2H3 YMVQALMWTZNEQG-UHFFFAOYSA-N 50068523 8-[3-(4-Fluoro-phenoxy)-propyl]-1-methyl-3-propyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL148749 D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068523&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10498944 103962726 CHEMBL148749 ZINC27559471 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118230 CN1CNC(=O)C11CCN(CCCOc2ccc(F)cc2)CC1 InChI=1S/C17H24FN3O2/c1-20-13-19-16(22)17(20)7-10-21(11-8-17)9-2-12-23-15-5-3-14(18)4-6-15/h3-6H,2,7-13H2,1H3,(H,19,22) VKWSFNFKZXJUPJ-UHFFFAOYSA-N 50068529 8-[3-(4-Fluoro-phenoxy)-propyl]-1-methyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL267204 D(2) dopamine receptor Rattus norvegicus 734 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068529&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10615765 103962732 CHEMBL267204 ZINC27561269 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118232 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.5 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118240 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)C1CCCCC1 InChI=1S/C23H32FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h8-11,20H,1-7,12-17H2,(H,25,29) DUQWSBIOJDFXKZ-UHFFFAOYSA-N 50068530 1-Cyclohexyl-8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL147449 D(2) dopamine receptor Rattus norvegicus 0.7 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365308 103962733 CHEMBL147449 ZINC12356328 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118242 CCCN1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C21H30FN3O2/c1-3-12-25-16-23(2)21(20(25)27)10-14-24(15-11-21)13-4-5-19(26)17-6-8-18(22)9-7-17/h6-9H,3-5,10-16H2,1-2H3 QLEPGKIQCRBVIL-UHFFFAOYSA-N 50068531 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1-methyl-3-propyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL150162 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11793887 103962734 CHEMBL150162 ZINC13782364 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118248 CN1CNC(=O)C11CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C18H24FN3O2/c1-21-13-20-17(24)18(21)8-11-22(12-9-18)10-2-3-16(23)14-4-6-15(19)7-5-14/h4-7H,2-3,8-13H2,1H3,(H,20,24) GRADLHIYNHRBCW-UHFFFAOYSA-N 50068519 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1-methyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL148413 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10404584 103962722 CHEMBL148413 ZINC36238048 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118252 NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)NC1CCCCC1 InChI=1S/C22H32FN3O2/c23-18-10-8-17(9-11-18)20(27)7-4-14-26-15-12-22(13-16-26,21(24)28)25-19-5-2-1-3-6-19/h8-11,19,25H,1-7,12-16H2,(H2,24,28) NJIUVZMPUMVXGO-UHFFFAOYSA-N 50068525 4-Cyclohexylamino-1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-piperidine-4-carboxylic acid amide::CHEMBL356075 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10715379 103962728 CHEMBL356075 ZINC27556965 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118253 CN1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C19H26FN3O2/c1-21-14-22(2)19(18(21)25)9-12-23(13-10-19)11-3-4-17(24)15-5-7-16(20)8-6-15/h5-8H,3-4,9-14H2,1-2H3 UEBHJYBPNYHDCW-UHFFFAOYSA-N 50068532 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1,3-dimethyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL146225 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10783864 103962735 CHEMBL146225 ZINC13782362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118258 CC(C)NC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)C(N)=O InChI=1S/C19H28FN3O2/c1-14(2)22-19(18(21)25)9-12-23(13-10-19)11-3-4-17(24)15-5-7-16(20)8-6-15/h5-8,14,22H,3-4,9-13H2,1-2H3,(H2,21,25) DQWLSHWCPUSFFO-UHFFFAOYSA-N 50068521 1-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-4-isopropylamino-piperidine-4-carboxylic acid amide::CHEMBL147418 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068521&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10807729 103962724 CHEMBL147418 ZINC27561273 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50118272 CC(C)N1CNC(=O)C11CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C20H28FN3O2/c1-15(2)24-14-22-19(26)20(24)9-12-23(13-10-20)11-3-4-18(25)16-5-7-17(21)8-6-16/h5-8,15H,3-4,9-14H2,1-2H3,(H,22,26) YCKVVNHIAYNYHI-UHFFFAOYSA-N 50068528 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-1-isopropyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL357924 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm980452a 10.7270/Q2CZ369B 9836624 Metwally, KA; Dukat, M; Egan, CT; Smith, C; DuPre, A; Gauthier, CB; Herrick-Davis, K; Teitler, M; Glennon, RA Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44365278 103962731 CHEMBL357924 ZINC13782359 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120572 Oc1ccc(cc1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-6-16(7-9-17)19-12-10-18(11-13-19)14-15-4-2-1-3-5-15/h1-9,20H,10-14H2 MKDLAVWJHBTGFQ-UHFFFAOYSA-N 50069910 4-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL103900 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069910&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8690650 103963872 CHEMBL103900 ZINC23466472 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120575 CS(=O)(=O)Nc1cc(OCCNCc2cccs2)ccc1Cl InChI=1S/C14H17ClN2O3S2/c1-22(18,19)17-14-9-11(4-5-13(14)15)20-7-6-16-10-12-3-2-8-21-12/h2-5,8-9,16-17H,6-7,10H2,1H3 RGVJFPMOLSXLGJ-UHFFFAOYSA-N 50069908 CHEMBL102490::N-(2-Chloro-5-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-phenyl)-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069908&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332701 103963870 CHEMBL102490 ZINC26823792 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120580 CS(=O)(=O)Nc1cc(OCCNCc2cccs2)ccc1F InChI=1S/C14H17FN2O3S2/c1-22(18,19)17-14-9-11(4-5-13(14)15)20-7-6-16-10-12-3-2-8-21-12/h2-5,8-9,16-17H,6-7,10H2,1H3 ORNYDPYZWVONOG-UHFFFAOYSA-N 50069913 CHEMBL101910::N-(2-Fluoro-5-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-phenyl)-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069913&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332613 103963875 CHEMBL101910 ZINC26820138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120589 CS(=O)(=O)Nc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C16H20N2O3S/c1-22(19,20)18-15-8-5-9-16(12-15)21-11-10-17-13-14-6-3-2-4-7-14/h2-9,12,17-18H,10-11,13H2,1H3 ZMVMIDCCNZYMFG-UHFFFAOYSA-N 50069918 CHEMBL99849::N-[3-(2-Benzylamino-ethoxy)-phenyl]-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069918&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332686 103963880 CHEMBL99849 ZINC26752574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120593 Oc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2 VBTFJGYCISLKEQ-UHFFFAOYSA-N 50069914 3-(2-Benzylamino-ethoxy)-phenol::CHEMBL64508 D(2) dopamine receptor Rattus norvegicus 101 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069914&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11776546 103963876 CHEMBL64508 ZINC12355952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120606 Oc1ccccc1N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-9-5-4-8-16(17)19-12-10-18(11-13-19)14-15-6-2-1-3-7-15/h1-9,20H,10-14H2 FPVKDWNGSLXDRY-UHFFFAOYSA-N 50069916 2-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL100952 D(2) dopamine receptor Rattus norvegicus 118 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069916&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8529065 103963878 CHEMBL100952 ZINC53165591 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119559 COc1ccccc1N1CCN(CCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C31H33N3O3/c1-37-28-16-9-8-15-27(28)33-21-19-32(20-22-33)17-10-18-34-29(35)23-26(31(34)36)30(24-11-4-2-5-12-24)25-13-6-3-7-14-25/h2-9,11-16H,10,17-23H2,1H3 FGEIPEJHLJEOQZ-UHFFFAOYSA-N 50069254 3-Benzhydrylidene-1-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL147954 D(2) dopamine receptor Rattus norvegicus 156 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9511274 103963362 CHEMBL147954 ZINC08398986 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119562 COc1ccccc1N1CCN(CCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C30H31N3O3/c1-36-27-15-9-8-14-26(27)32-19-16-31(17-20-32)18-21-33-28(34)22-25(30(33)35)29(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-15H,16-22H2,1H3 UHDVIHZGYVYYEM-UHFFFAOYSA-N 50069256 3-Benzhydrylidene-1-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL424115 D(2) dopamine receptor Rattus norvegicus 167 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5015788 103963364 CHEMBL424115 ZINC53255598 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119565 FC(F)(F)c1cccc(c1)N1CCN(CCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C30H28F3N3O2/c31-30(32,33)24-12-7-13-25(20-24)35-17-14-34(15-18-35)16-19-36-27(37)21-26(29(36)38)28(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,20H,14-19,21H2 UWCMIDIOYALUAY-UHFFFAOYSA-N 50069253 3-Benzhydrylidene-1-{2-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL356788 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069253&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 986000 103963361 CHEMBL356788 ZINC53092588 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120608 Oc1ccc2OC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C16H17NO3/c18-13-6-7-15-16(8-13)20-14(11-19-15)10-17-9-12-4-2-1-3-5-12/h1-8,14,17-18H,9-11H2/t14-/m0/s1 DYWYWIOQKKRAST-AWEZNQCLSA-N 50061642 (S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]dioxin-6-ol; oxalic acid::CHEMBL300571::CHEMBL423890 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10612157 103957192 CHEMBL300571CHEMBL423890 ZINC13775979 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120612 Nc1cc(OCCNCc2ccccc2)ccc1Cl InChI=1S/C15H17ClN2O/c16-14-7-6-13(10-15(14)17)19-9-8-18-11-12-4-2-1-3-5-12/h1-7,10,18H,8-9,11,17H2 MSJYXZAZPCPYHS-UHFFFAOYSA-N 50069920 5-(2-Benzylamino-ethoxy)-2-chloro-phenylamine::CHEMBL319816 D(2) dopamine receptor Rattus norvegicus 237.0 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069920&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332566 103963882 CHEMBL319816 ZINC26752285 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120618 Oc1ccc(OCCNCc2ccccc2)cc1 InChI=1S/C15H17NO2/c17-14-6-8-15(9-7-14)18-11-10-16-12-13-4-2-1-3-5-13/h1-9,16-17H,10-12H2 JADOYZZQMNOBML-UHFFFAOYSA-N 50069909 4-(2-Benzylamino-ethoxy)-phenol::CHEMBL100461 D(2) dopamine receptor Rattus norvegicus 113 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069909&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15034333 103963871 CHEMBL100461 ZINC26751661 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50120647 C(COc1ccccc1)NCc1ccccc1 InChI=1S/C15H17NO/c1-3-7-14(8-4-1)13-16-11-12-17-15-9-5-2-6-10-15/h1-10,16H,11-13H2 XTNXLNGNJZRBRW-UHFFFAOYSA-N 50069917 Benzyl-(2-phenoxy-ethyl)-amine::CHEMBL103951 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1016/s0960-894x(98)00014-6 10.7270/Q28W3CG1 9871673 Mewshaw, RE; Husbands, M; Gildersleeve, ES; Webb, MB; Shi, X; Mazandarani, H; Cockett, MI; Ochalski, R; Brennan, JA; Abou-Gharbia, M; Marquis, K; McGaughey, GB; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20256387 103963879 CHEMBL103951 ZINC26816095 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119577 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C32H32F3N3O2/c33-32(34,35)26-14-9-15-27(22-26)37-20-18-36(19-21-37)16-7-8-17-38-29(39)23-28(31(38)40)30(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-6,9-15,22H,7-8,16-21,23H2 FMXLYBQQAIUKMP-UHFFFAOYSA-N 50069260 3-Benzhydrylidene-1-{4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL144210 D(2) dopamine receptor Rattus norvegicus 689.0 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069260&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10768967 103963368 CHEMBL144210 ZINC27551422 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119581 Clc1cccc(c1)N1CCN(CCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C30H30ClN3O2/c31-25-13-7-14-26(21-25)33-19-17-32(18-20-33)15-8-16-34-28(35)22-27(30(34)36)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-7,9-14,21H,8,15-20,22H2 LLGZHXKYLRDRCB-UHFFFAOYSA-N 50069264 3-Benzhydrylidene-1-{3-[4-(3-chloro-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL358580 D(2) dopamine receptor Rattus norvegicus 801 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069264&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9511277 103963372 CHEMBL358580 ZINC08398990 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119582 Clc1cccc(c1)N1CCN(CCCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C31H32ClN3O2/c32-26-14-9-15-27(22-26)34-20-18-33(19-21-34)16-7-8-17-35-29(36)23-28(31(35)37)30(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-6,9-15,22H,7-8,16-21,23H2 ROGAOFMHAQAPFV-UHFFFAOYSA-N 59418 1-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-3-(diphenylmethylene)pyrrolidine-2,5-dione;hydrochloride::1-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]-3-(diphenylmethylidene)pyrrolidine-2,5-dione;hydrochloride::1-{4-[4-(3-chlorophenyl)-1-piperazinyl]butyl}-3-(diphenylmethylene)-2,5-pyrrolidinedione::3-benzhydrylidene-1-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]pyrrolidine-2,5-dione;hydrochloride::3-benzhydrylidene-1-[4-[4-(3-chlorophenyl)piperazino]butyl]pyrrolidine-2,5-quinone;hydrochloride::CHEMBL356965::MLS000538136::SMR000161527::cid_11948776 D(2) dopamine receptor Rattus norvegicus 367 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=59418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=59418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4557684 252639054 CHEMBL356965 ZINC08399005 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119584 O=C1CC(=C(c2ccccc2)c2ccccc2)C(=O)N1CCCN1CCN(CC1)c1ccccc1 InChI=1S/C30H31N3O2/c34-28-23-27(29(24-11-4-1-5-12-24)25-13-6-2-7-14-25)30(35)33(28)18-10-17-31-19-21-32(22-20-31)26-15-8-3-9-16-26/h1-9,11-16H,10,17-23H2 XPGQLDMKJHVVMR-UHFFFAOYSA-N 50069265 3-Benzhydrylidene-1-[3-(4-phenyl-piperazin-1-yl)-propyl]-pyrrolidine-2,5-dione::CHEMBL144876 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069265&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10742822 103963373 CHEMBL144876 ZINC13782632 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119587 FC(F)(F)c1cccc(c1)N1CCN(CCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C31H30F3N3O2/c32-31(33,34)25-13-7-14-26(21-25)36-19-17-35(18-20-36)15-8-16-37-28(38)22-27(30(37)39)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-7,9-14,21H,8,15-20,22H2 FBICEOFMWBPEIA-UHFFFAOYSA-N 50069259 3-Benzhydrylidene-1-{3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL144498 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069259&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10626124 103963367 CHEMBL144498 ZINC27551384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119589 COc1ccccc1N1CCN(CN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C29H29N3O3/c1-35-26-15-9-8-14-25(26)31-18-16-30(17-19-31)21-32-27(33)20-24(29(32)34)28(22-10-4-2-5-11-22)23-12-6-3-7-13-23/h2-15H,16-21H2,1H3 DXJGVJWQCJZBOK-UHFFFAOYSA-N 50069262 3-Benzhydrylidene-1-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL145399 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069262&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10790414 103963370 CHEMBL145399 ZINC13782624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119591 FC(F)(F)c1cccc(c1)N1CCN(CN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C29H26F3N3O2/c30-29(31,32)23-12-7-13-24(18-23)34-16-14-33(15-17-34)20-35-26(36)19-25(28(35)37)27(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,18H,14-17,19-20H2 HECJDRZLPLNMAE-UHFFFAOYSA-N 50069257 3-Benzhydrylidene-1-[4-(3-trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL148114 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9983639 103963365 CHEMBL148114 ZINC27554036 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119592 O=C1CC(=C(c2ccccc2)c2ccccc2)C(=O)N1CCN1CCN(CC1)c1ccccc1 InChI=1S/C29H29N3O2/c33-27-22-26(28(23-10-4-1-5-11-23)24-12-6-2-7-13-24)29(34)32(27)21-18-30-16-19-31(20-17-30)25-14-8-3-9-15-25/h1-15H,16-22H2 SDEFLOZFNIEWNL-UHFFFAOYSA-N 50069263 3-Benzhydrylidene-1-[2-(4-phenyl-piperazin-1-yl)-ethyl]-pyrrolidine-2,5-dione::CHEMBL343886 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069263&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 985994 103963371 CHEMBL343886 ZINC53057372 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119593 Fc1ccc(cc1)N1CCN(CCCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C31H32FN3O2/c32-26-13-15-27(16-14-26)34-21-19-33(20-22-34)17-7-8-18-35-29(36)23-28(31(35)37)30(24-9-3-1-4-10-24)25-11-5-2-6-12-25/h1-6,9-16H,7-8,17-23H2 ODZUETXEDAFLSP-UHFFFAOYSA-N 50069258 3-Benzhydrylidene-1-{4-[4-(4-fluoro-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL435869 D(2) dopamine receptor Rattus norvegicus 351.0 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069258&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4603931 103963366 CHEMBL435869 ZINC03821115 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119594 Clc1cccc(c1)N1CCN(CN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C28H26ClN3O2/c29-23-12-7-13-24(18-23)31-16-14-30(15-17-31)20-32-26(33)19-25(28(32)34)27(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,18H,14-17,19-20H2 WLTQYNKWRRSAGS-UHFFFAOYSA-N 50069250 3-Benzhydrylidene-1-[4-(3-chloro-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL343841 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10743038 103963358 CHEMBL343841 ZINC13782625 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119595 O=C1CC(=C(c2ccccc2)c2ccccc2)C(=O)N1CCCCN1CCN(CC1)c1ccccc1 InChI=1S/C31H33N3O2/c35-29-24-28(30(25-12-4-1-5-13-25)26-14-6-2-7-15-26)31(36)34(29)19-11-10-18-32-20-22-33(23-21-32)27-16-8-3-9-17-27/h1-9,12-17H,10-11,18-24H2 QFESFPVBIJPECI-UHFFFAOYSA-N 50069261 3-Benzhydrylidene-1-[4-(4-phenyl-piperazin-1-yl)-butyl]-pyrrolidine-2,5-dione::CHEMBL342995::cid_9511286 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069261&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9511286 103963369 CHEMBL342995 ZINC08398997 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119596 Fc1ccc(cc1)N1CCN(CN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C28H26FN3O2/c29-23-11-13-24(14-12-23)31-17-15-30(16-18-31)20-32-26(33)19-25(28(32)34)27(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-14H,15-20H2 FZPIMABHDJIBBC-UHFFFAOYSA-N 50069267 3-Benzhydrylidene-1-[4-(4-fluoro-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL357687 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069267&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10479162 103963375 CHEMBL357687 ZINC13782626 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119597 Fc1ccc(cc1)N1CCN(CCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C29H28FN3O2/c30-24-11-13-25(14-12-24)32-18-15-31(16-19-32)17-20-33-27(34)21-26(29(33)35)28(22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-14H,15-21H2 SLHOTSULTKLUPX-UHFFFAOYSA-N 50069252 3-Benzhydrylidene-1-{2-[4-(4-fluoro-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL144158 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069252&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 986003 103963360 CHEMBL144158 ZINC53219112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119598 Clc1cccc(c1)N1CCN(CCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C29H28ClN3O2/c30-24-12-7-13-25(20-24)32-17-14-31(15-18-32)16-19-33-27(34)21-26(29(33)35)28(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,20H,14-19,21H2 DUNVJMUDRYGZSU-UHFFFAOYSA-N 50069251 3-Benzhydrylidene-1-{2-[4-(3-chloro-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL356930 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 985997 103963359 CHEMBL356930 ZINC19911456 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119602 O=C1CC(=C(c2ccccc2)c2ccccc2)C(=O)N1CN1CCN(CC1)c1ccccc1 InChI=1S/C28H27N3O2/c32-26-20-25(27(22-10-4-1-5-11-22)23-12-6-2-7-13-23)28(33)31(26)21-29-16-18-30(19-17-29)24-14-8-3-9-15-24/h1-15H,16-21H2 DSXRNFYZQWFLRJ-UHFFFAOYSA-N 50069266 3-Benzhydrylidene-1-(4-phenyl-piperazin-1-ylmethyl)-pyrrolidine-2,5-dione::CHEMBL147718 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069266&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10646641 103963374 CHEMBL147718 ZINC13782623 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119607 COc1ccccc1N1CCN(CCCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C32H35N3O3/c1-38-29-17-9-8-16-28(29)34-22-20-33(21-23-34)18-10-11-19-35-30(36)24-27(32(35)37)31(25-12-4-2-5-13-25)26-14-6-3-7-15-26/h2-9,12-17H,10-11,18-24H2,1H3 ZCMZZNFJNSIGCM-UHFFFAOYSA-N 50069249 3-Benzhydrylidene-1-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL144157 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4673621 103963357 CHEMBL144157 ZINC08399000 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50119610 Fc1ccc(cc1)N1CCN(CCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C30H30FN3O2/c31-25-12-14-26(15-13-25)33-20-18-32(19-21-33)16-7-17-34-28(35)22-27(30(34)36)29(23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-6,8-15H,7,16-22H2 WSEDALHSRBCEIG-UHFFFAOYSA-N 50069268 3-Benzhydrylidene-1-{3-[4-(4-fluoro-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL356128 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00074-2 10.7270/Q2N878XB 9871564 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Sanz, AM; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069268&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10696203 103963376 CHEMBL356128 ZINC13782633 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121844 CCN1CCN(C)C[C@@H](C1)NC(=O)c1cc(Cl)c(NC)nc1OC InChI=1S/C16H26ClN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m0/s1 UXEPXLWCTJUUTO-NSHDSACASA-N 50070564 5-Chloro-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL432284 D(2) dopamine receptor Rattus norvegicus 202 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10937177 103964417 CHEMBL432284 ZINC22928205 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121846 CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(NC)nc1OC InChI=1S/C16H26ClN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23) UXEPXLWCTJUUTO-UHFFFAOYSA-N 50070565 5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL39016 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285961 103964418 CHEMBL39016 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121848 CCNc1nc(OC)c(cc1Br)C(=O)NC1CN(C)CCN(CC)C1 InChI=1S/C17H28BrN5O2/c1-5-19-15-14(18)9-13(17(21-15)25-4)16(24)20-12-10-22(3)7-8-23(6-2)11-12/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24) YEQZXAIWXAPBHX-UHFFFAOYSA-N 50070567 5-Bromo-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide::CHEMBL287760 D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11732423 103964420 CHEMBL287760 ZINC22928189 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121849 CCN1CCN(C)CC(C1)NC(=O)c1cc(Br)c(nc1OC)N(C)C InChI=1S/C17H28BrN5O2/c1-6-23-8-7-22(4)10-12(11-23)19-16(24)13-9-14(18)15(21(2)3)20-17(13)25-5/h9,12H,6-8,10-11H2,1-5H3,(H,19,24) JHFICXQBISNVSL-UHFFFAOYSA-N 50070568 5-Bromo-6-dimethylamino-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide::CHEMBL291296 D(2) dopamine receptor Rattus norvegicus 75 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11047938 103964421 CHEMBL291296 ZINC36093047 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121850 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(NC)nc1OC InChI=1S/C16H26ClN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m1/s1 UXEPXLWCTJUUTO-LLVKDONJSA-N 50070569 5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL38969 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11810408 103964422 CHEMBL38969 ZINC22928157 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121854 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Br)c(NC)nc1OC InChI=1S/C16H26BrN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m1/s1 FKDXBULKZKICQO-LLVKDONJSA-N 50070571 5-Bromo-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL416047 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9843910 103964424 CHEMBL416047 ZINC22448624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121855 CCN1CCN(C)C[C@@H](C1)NC(=O)c1cc(Br)c(NC)nc1OC InChI=1S/C16H26BrN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m0/s1 FKDXBULKZKICQO-NSHDSACASA-N 50070566 5-Bromo-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL40497 D(2) dopamine receptor Rattus norvegicus 81 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10894643 103964419 CHEMBL40497 ZINC19359121 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121856 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(NC)cc1OC InChI=1S/C17H27ClN4O2/c1-5-22-7-6-21(3)10-12(11-22)20-17(23)13-8-14(18)15(19-2)9-16(13)24-4/h8-9,12,19H,5-7,10-11H2,1-4H3,(H,20,23)/t12-/m1/s1 WKQKHFBNIGVTEQ-GFCCVEGCSA-N 50070570 5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-4-methylamino-benzamide::CHEMBL40082 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11002742 103964423 CHEMBL40082 ZINC22452401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121858 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 480 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121862 CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(N)nc1OC InChI=1S/C15H24ClN5O2/c1-4-21-6-5-20(2)8-10(9-21)18-14(22)11-7-12(16)13(17)19-15(11)23-3/h7,10H,4-6,8-9H2,1-3H3,(H2,17,19)(H,18,22) NQAOXCXKUPNSLL-UHFFFAOYSA-N 50070572 6-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide::CHEMBL290959 D(2) dopamine receptor Rattus norvegicus 386 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10860791 103964425 CHEMBL290959 ZINC36093046 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121864 CCNc1nc(OC)c(cc1Cl)C(=O)NC1CN(C)CCN(CC)C1 InChI=1S/C17H28ClN5O2/c1-5-19-15-14(18)9-13(17(21-15)25-4)16(24)20-12-10-22(3)7-8-23(6-2)11-12/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24) KCVFDLHNTSZQNS-UHFFFAOYSA-N 50070573 5-Chloro-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide::CHEMBL38473 D(2) dopamine receptor Rattus norvegicus 76 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11003173 103964426 CHEMBL38473 ZINC22928167 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50121865 CCN1CCN(C)CC(C1)NC(=O)c1cc(Br)c(NC)nc1OC InChI=1S/C16H26BrN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23) FKDXBULKZKICQO-UHFFFAOYSA-N 50070574 5-Bromo-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL40903 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1016/s0960-894x(98)00258-3 10.7270/Q2CF9P7B 9873388 Hirokawa, Y; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21852725 103964427 CHEMBL40903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126171 Clc1cccc(c1)N1CCN(CN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C28H24ClN3O2/c29-19-6-5-7-20(16-19)31-14-12-30(13-15-31)18-32-26(33)17-25(28(32)34)27-23-10-3-1-8-21(23)22-9-2-4-11-24(22)27/h1-11,16H,12-15,17-18H2 VEGNRBAKYMVKPF-UHFFFAOYSA-N 50072872 1-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-3-fluoren-9-ylidene-pyrrolidine-2,5-dione::CHEMBL148126 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10576301 103966463 CHEMBL148126 ZINC13782629 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126172 O=C1CC(C(=O)N1CCN1CCN(CC1)c1ccccc1)=C1c2ccccc2-c2ccccc12 InChI=1S/C29H27N3O2/c33-27-20-26(28-24-12-6-4-10-22(24)23-11-5-7-13-25(23)28)29(34)32(27)19-16-30-14-17-31(18-15-30)21-8-2-1-3-9-21/h1-13H,14-20H2 YXACXWLALINXQS-UHFFFAOYSA-N 50072873 3-Fluoren-9-ylidene-1-[2-(4-phenyl-piperazin-1-yl)-ethyl]-pyrrolidine-2,5-dione::CHEMBL146166 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072873&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 986005 103966464 CHEMBL146166 ZINC53224602 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126175 Clc1cccc(c1)N1CCN(CCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C29H26ClN3O2/c30-20-6-5-7-21(18-20)32-15-12-31(13-16-32)14-17-33-27(34)19-26(29(33)35)28-24-10-3-1-8-22(24)23-9-2-4-11-25(23)28/h1-11,18H,12-17,19H2 JEAQLWJWPZGRJC-UHFFFAOYSA-N 50072875 1-{2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-ethyl}-3-fluoren-9-ylidene-pyrrolidine-2,5-dione::CHEMBL147567::cid_986007 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072875&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 986007 103966466 CHEMBL147567 ZINC19911458 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126177 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C32H32F3N3O2/c33-32(34,35)26-14-9-15-27(22-26)37-20-18-36(19-21-37)16-7-8-17-38-29(39)23-28(31(38)40)30(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-6,9-15,22H,7-8,16-21,23H2 FMXLYBQQAIUKMP-UHFFFAOYSA-N 50069260 3-Benzhydrylidene-1-{4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL144210 D(2) dopamine receptor Rattus norvegicus 689.0 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069260&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10768967 103963368 CHEMBL144210 ZINC27551422 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126181 COc1ccccc1N1CCN(CCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C30H29N3O3/c1-36-27-13-7-6-12-26(27)32-17-14-31(15-18-32)16-19-33-28(34)20-25(30(33)35)29-23-10-4-2-8-21(23)22-9-3-5-11-24(22)29/h2-13H,14-20H2,1H3 PZWNEECYKUPZOR-UHFFFAOYSA-N 50072871 3-Fluoren-9-ylidene-1-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL356276 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 986006 103966462 CHEMBL356276 ZINC53092585 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126182 COc1ccccc1N1CCN(CCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C30H31N3O3/c1-36-27-15-9-8-14-26(27)32-19-16-31(17-20-32)18-21-33-28(34)22-25(30(33)35)29(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-15H,16-22H2,1H3 UHDVIHZGYVYYEM-UHFFFAOYSA-N 50069256 3-Benzhydrylidene-1-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL424115 D(2) dopamine receptor Rattus norvegicus 167 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5015788 103963364 CHEMBL424115 ZINC53255598 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126184 FC(F)(F)c1cccc(c1)N1CCN(CCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C30H28F3N3O2/c31-30(32,33)24-12-7-13-25(20-24)35-17-14-34(15-18-35)16-19-36-27(37)21-26(29(36)38)28(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,20H,14-19,21H2 UWCMIDIOYALUAY-UHFFFAOYSA-N 50069253 3-Benzhydrylidene-1-{2-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL356788 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069253&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 986000 103963361 CHEMBL356788 ZINC53092588 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126185 COc1ccccc1N1CCN(CN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C29H27N3O3/c1-35-26-13-7-6-12-25(26)31-16-14-30(15-17-31)19-32-27(33)18-24(29(32)34)28-22-10-4-2-8-20(22)21-9-3-5-11-23(21)28/h2-13H,14-19H2,1H3 IHBNUZUTLCCGGH-UHFFFAOYSA-N 50072878 3-Fluoren-9-ylidene-1-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL143616 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072878&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10624047 103966469 CHEMBL143616 ZINC13782628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126186 FC(F)(F)c1cccc(c1)N1CCN(CCCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C31H28F3N3O2/c32-31(33,34)21-7-5-8-22(19-21)36-17-15-35(16-18-36)13-6-14-37-28(38)20-27(30(37)39)29-25-11-3-1-9-23(25)24-10-2-4-12-26(24)29/h1-5,7-12,19H,6,13-18,20H2 NKFYFKVMXRDNEH-UHFFFAOYSA-N 50072879 3-Fluoren-9-ylidene-1-{3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL143221 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072879&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10768574 103966470 CHEMBL143221 ZINC27549630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126188 COc1ccccc1N1CCN(CCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C31H33N3O3/c1-37-28-16-9-8-15-27(28)33-21-19-32(20-22-33)17-10-18-34-29(35)23-26(31(34)36)30(24-11-4-2-5-12-24)25-13-6-3-7-14-25/h2-9,11-16H,10,17-23H2,1H3 FGEIPEJHLJEOQZ-UHFFFAOYSA-N 50069254 3-Benzhydrylidene-1-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL147954 D(2) dopamine receptor Rattus norvegicus 156 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9511274 103963362 CHEMBL147954 ZINC08398986 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126194 Fc1ccc(cc1)N1CCN(CCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C30H30FN3O2/c31-25-12-14-26(15-13-25)33-20-18-32(19-21-33)16-7-17-34-28(35)22-27(30(34)36)29(23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-6,8-15H,7,16-22H2 WSEDALHSRBCEIG-UHFFFAOYSA-N 50069268 3-Benzhydrylidene-1-{3-[4-(4-fluoro-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL356128 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069268&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10696203 103963376 CHEMBL356128 ZINC13782633 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126195 Clc1cccc(c1)N1CCN(CCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C29H28ClN3O2/c30-24-12-7-13-25(20-24)32-17-14-31(15-18-32)16-19-33-27(34)21-26(29(33)35)28(22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-13,20H,14-19,21H2 DUNVJMUDRYGZSU-UHFFFAOYSA-N 50069251 3-Benzhydrylidene-1-{2-[4-(3-chloro-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL356930 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 985997 103963359 CHEMBL356930 ZINC19911456 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126203 Clc1cccc(c1)N1CCN(CN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C28H26ClN3O2/c29-23-12-7-13-24(18-23)31-16-14-30(15-17-31)20-32-26(33)19-25(28(32)34)27(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,18H,14-17,19-20H2 WLTQYNKWRRSAGS-UHFFFAOYSA-N 50069250 3-Benzhydrylidene-1-[4-(3-chloro-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL343841 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10743038 103963358 CHEMBL343841 ZINC13782625 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126206 COc1ccccc1N1CCN(CCCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C31H31N3O3/c1-37-28-14-7-6-13-27(28)33-19-17-32(18-20-33)15-8-16-34-29(35)21-26(31(34)36)30-24-11-4-2-9-22(24)23-10-3-5-12-25(23)30/h2-7,9-14H,8,15-21H2,1H3 QVLZRPLBLMCLNA-UHFFFAOYSA-N 50072876 3-Fluoren-9-ylidene-1-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL144846 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072876&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 986012 103966467 CHEMBL144846 ZINC08398994 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126207 Fc1ccc(cc1)N1CCN(CCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C29H28FN3O2/c30-24-11-13-25(14-12-24)32-18-15-31(16-19-32)17-20-33-27(34)21-26(29(33)35)28(22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-14H,15-21H2 SLHOTSULTKLUPX-UHFFFAOYSA-N 50069252 3-Benzhydrylidene-1-{2-[4-(4-fluoro-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL144158 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069252&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 986003 103963360 CHEMBL144158 ZINC53219112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126210 COc1ccccc1N1CCN(CN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C29H29N3O3/c1-35-26-15-9-8-14-25(26)31-18-16-30(17-19-31)21-32-27(33)20-24(29(32)34)28(22-10-4-2-5-11-22)23-12-6-3-7-13-23/h2-15H,16-21H2,1H3 DXJGVJWQCJZBOK-UHFFFAOYSA-N 50069262 3-Benzhydrylidene-1-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL145399 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069262&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10790414 103963370 CHEMBL145399 ZINC13782624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126211 O=C1CC(=C(c2ccccc2)c2ccccc2)C(=O)N1CCN1CCN(CC1)c1ccccc1 InChI=1S/C29H29N3O2/c33-27-22-26(28(23-10-4-1-5-11-23)24-12-6-2-7-13-24)29(34)32(27)21-18-30-16-19-31(20-17-30)25-14-8-3-9-15-25/h1-15H,16-22H2 SDEFLOZFNIEWNL-UHFFFAOYSA-N 50069263 3-Benzhydrylidene-1-[2-(4-phenyl-piperazin-1-yl)-ethyl]-pyrrolidine-2,5-dione::CHEMBL343886 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069263&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 985994 103963371 CHEMBL343886 ZINC53057372 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126214 Fc1ccc(cc1)N1CCN(CCCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C31H32FN3O2/c32-26-13-15-27(16-14-26)34-21-19-33(20-22-34)17-7-8-18-35-29(36)23-28(31(35)37)30(24-9-3-1-4-10-24)25-11-5-2-6-12-25/h1-6,9-16H,7-8,17-23H2 ODZUETXEDAFLSP-UHFFFAOYSA-N 50069258 3-Benzhydrylidene-1-{4-[4-(4-fluoro-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL435869 D(2) dopamine receptor Rattus norvegicus 351.0 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069258&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4603931 103963366 CHEMBL435869 ZINC03821115 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126222 O=C1CC(=C(c2ccccc2)c2ccccc2)C(=O)N1CN1CCN(CC1)c1ccccc1 InChI=1S/C28H27N3O2/c32-26-20-25(27(22-10-4-1-5-11-22)23-12-6-2-7-13-23)28(33)31(26)21-29-16-18-30(19-17-29)24-14-8-3-9-15-24/h1-15H,16-21H2 DSXRNFYZQWFLRJ-UHFFFAOYSA-N 50069266 3-Benzhydrylidene-1-(4-phenyl-piperazin-1-ylmethyl)-pyrrolidine-2,5-dione::CHEMBL147718 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069266&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10646641 103963374 CHEMBL147718 ZINC13782623 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50574969 O=C1CC(CN2CCOCC2)Cc2[nH]c3ccccc3c12 InChI=1S/C17H20N2O2/c20-16-10-12(11-19-5-7-21-8-6-19)9-15-17(16)13-3-1-2-4-14(13)18-15/h1-4,12,18H,5-11H2 WMHDJYIJHLDOPN-UHFFFAOYSA-N 50215378 CHEMBL327038 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1016/s0960-894x(98)00639-8 10.7270/Q26H4JKD 9934473 Masaguer, CF; Formoso, E; Ravina, E; Tristan, H; Loza, MI; Rivas, E; Fontenla, JA Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10517193 376071683 CHEMBL327038 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50574970 CCN(CC)CC1Cc2c(C(=O)C1)c1ccccc1n2C InChI=1S/C18H24N2O/c1-4-20(5-2)12-13-10-16-18(17(21)11-13)14-8-6-7-9-15(14)19(16)3/h6-9,13H,4-5,10-12H2,1-3H3 QFCOCPQCMWDBNO-UHFFFAOYSA-N 50215389 CHEMBL118477 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1016/s0960-894x(98)00639-8 10.7270/Q26H4JKD 9934473 Masaguer, CF; Formoso, E; Ravina, E; Tristan, H; Loza, MI; Rivas, E; Fontenla, JA Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215389&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10660751 376071684 CHEMBL118477 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50574971 Fc1ccc(cc1)C(=O)C1CCN(CC2Cc3[nH]c4ccccc4c3C(=O)C2)CC1 InChI=1S/C25H25FN2O2/c26-19-7-5-17(6-8-19)25(30)18-9-11-28(12-10-18)15-16-13-22-24(23(29)14-16)20-3-1-2-4-21(20)27-22/h1-8,16,18,27H,9-15H2 OZMFVKDFRHXPOM-UHFFFAOYSA-N 50403684 CHEMBL120903 D(2) dopamine receptor Rattus norvegicus 562 ChEMBL 10.1016/s0960-894x(98)00639-8 10.7270/Q26H4JKD 9934473 Masaguer, CF; Formoso, E; Ravina, E; Tristan, H; Loza, MI; Rivas, E; Fontenla, JA Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10069784 163352708 CHEMBL120903 ZINC13471720 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50574972 Fc1ccc2c(noc2c1)C1CCN(CC2Cc3[nH]c4ccccc4c3C(=O)C2)CC1 InChI=1S/C25H24FN3O2/c26-17-5-6-19-23(13-17)31-28-25(19)16-7-9-29(10-8-16)14-15-11-21-24(22(30)12-15)18-3-1-2-4-20(18)27-21/h1-6,13,15-16,27H,7-12,14H2 SPBXLWNNWOLJEO-UHFFFAOYSA-N 50403683 CHEMBL333174 D(2) dopamine receptor Rattus norvegicus 141 ChEMBL 10.1016/s0960-894x(98)00639-8 10.7270/Q26H4JKD 9934473 Masaguer, CF; Formoso, E; Ravina, E; Tristan, H; Loza, MI; Rivas, E; Fontenla, JA Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403683&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9866660 163352707 CHEMBL333174 ZINC13471721 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50574973 CCN(CC)CC1Cc2[nH]c3ccccc3c2C(=O)C1 InChI=1S/C17H22N2O/c1-3-19(4-2)11-12-9-15-17(16(20)10-12)13-7-5-6-8-14(13)18-15/h5-8,12,18H,3-4,9-11H2,1-2H3 LMMAILCVHOFRRB-UHFFFAOYSA-N 50215377 CHEMBL118947 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1016/s0960-894x(98)00639-8 10.7270/Q26H4JKD 9934473 Masaguer, CF; Formoso, E; Ravina, E; Tristan, H; Loza, MI; Rivas, E; Fontenla, JA Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10492294 376071682 CHEMBL118947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50574974 COc1ccccc1N1CCN(CC2Cc3[nH]c4ccccc4c3C(=O)C2)CC1 InChI=1S/C24H27N3O2/c1-29-23-9-5-4-8-21(23)27-12-10-26(11-13-27)16-17-14-20-24(22(28)15-17)18-6-2-3-7-19(18)25-20/h2-9,17,25H,10-16H2,1H3 IHQJQJGQVPNKSI-UHFFFAOYSA-N 50403682 CHEMBL121744 D(2) dopamine receptor Rattus norvegicus 1549 ChEMBL 10.1016/s0960-894x(98)00639-8 10.7270/Q26H4JKD 9934473 Masaguer, CF; Formoso, E; Ravina, E; Tristan, H; Loza, MI; Rivas, E; Fontenla, JA Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403682&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10715378 163352706 CHEMBL121744 ZINC13471718 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126225 O=C1CC(C(=O)N1CN1CCN(CC1)c1ccccc1)=C1c2ccccc2-c2ccccc12 InChI=1S/C28H25N3O2/c32-26-18-25(27-23-12-6-4-10-21(23)22-11-5-7-13-24(22)27)28(33)31(26)19-29-14-16-30(17-15-29)20-8-2-1-3-9-20/h1-13H,14-19H2 RDQVQURVQZZGLH-UHFFFAOYSA-N 50072884 3-Fluoren-9-ylidene-1-(4-phenyl-piperazin-1-ylmethyl)-pyrrolidine-2,5-dione::CHEMBL148119 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10812795 103966475 CHEMBL148119 ZINC13782627 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126230 O=C1CC(C(=O)N1CCCN1CCN(CC1)c1ccccc1)=C1c2ccccc2-c2ccccc12 InChI=1S/C30H29N3O2/c34-28-21-27(29-25-13-6-4-11-23(25)24-12-5-7-14-26(24)29)30(35)33(28)16-8-15-31-17-19-32(20-18-31)22-9-2-1-3-10-22/h1-7,9-14H,8,15-21H2 CQVULHXMNDQWED-UHFFFAOYSA-N 50072887 3-Fluoren-9-ylidene-1-[3-(4-phenyl-piperazin-1-yl)-propyl]-pyrrolidine-2,5-dione::CHEMBL145700 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072887&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10695413 103966478 CHEMBL145700 ZINC13782634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126231 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C32H30F3N3O2/c33-32(34,35)22-8-7-9-23(20-22)37-18-16-36(17-19-37)14-5-6-15-38-29(39)21-28(31(38)40)30-26-12-3-1-10-24(26)25-11-2-4-13-27(25)30/h1-4,7-13,20H,5-6,14-19,21H2 NGYMIVILOPOFDQ-UHFFFAOYSA-N 50072883 3-Fluoren-9-ylidene-1-{4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL144189 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072883&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3447482 103966474 CHEMBL144189 ZINC08399010 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126234 Clc1cccc(c1)N1CCN(CCCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C30H28ClN3O2/c31-21-7-5-8-22(19-21)33-17-15-32(16-18-33)13-6-14-34-28(35)20-27(30(34)36)29-25-11-3-1-9-23(25)24-10-2-4-12-26(24)29/h1-5,7-12,19H,6,13-18,20H2 KPSUCSFDXUGYRG-UHFFFAOYSA-N 50072888 1-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-3-fluoren-9-ylidene-pyrrolidine-2,5-dione::CHEMBL144544 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10815166 103966479 CHEMBL144544 ZINC13782644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126239 Fc1ccc(cc1)N1CCN(CCCCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C31H30FN3O2/c32-22-11-13-23(14-12-22)34-19-17-33(18-20-34)15-5-6-16-35-29(36)21-28(31(35)37)30-26-9-3-1-7-24(26)25-8-2-4-10-27(25)30/h1-4,7-14H,5-6,15-21H2 UBBXGQZDMHJNSX-UHFFFAOYSA-N 50072885 3-Fluoren-9-ylidene-1-{4-[4-(4-fluoro-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL144008 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10743836 103966476 CHEMBL144008 ZINC13782638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126241 Fc1ccc(cc1)N1CCN(CCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C29H26FN3O2/c30-20-9-11-21(12-10-20)32-16-13-31(14-17-32)15-18-33-27(34)19-26(29(33)35)28-24-7-3-1-5-22(24)23-6-2-4-8-25(23)28/h1-12H,13-19H2 GFZZPPRJKLLBCP-UHFFFAOYSA-N 50072889 3-Fluoren-9-ylidene-1-{2-[4-(4-fluoro-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL148059 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072889&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10742880 103966480 CHEMBL148059 ZINC13782631 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126245 Clc1cccc(c1)N1CCN(CCCCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C31H30ClN3O2/c32-22-8-7-9-23(20-22)34-18-16-33(17-19-34)14-5-6-15-35-29(36)21-28(31(35)37)30-26-12-3-1-10-24(26)25-11-2-4-13-27(25)30/h1-4,7-13,20H,5-6,14-19,21H2 BMFXKJVYUBXLFG-UHFFFAOYSA-N 50072874 1-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-3-fluoren-9-ylidene-pyrrolidine-2,5-dione::CHEMBL144097 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10673318 103966465 CHEMBL144097 ZINC13782637 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126246 COc1ccccc1N1CCN(CCCCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C32H33N3O3/c1-38-29-15-7-6-14-28(29)34-20-18-33(19-21-34)16-8-9-17-35-30(36)22-27(32(35)37)31-25-12-4-2-10-23(25)24-11-3-5-13-26(24)31/h2-7,10-15H,8-9,16-22H2,1H3 NONPAEZYCDCBMY-UHFFFAOYSA-N 50072880 3-Fluoren-9-ylidene-1-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL144343 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072880&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10767920 103966471 CHEMBL144343 ZINC13782636 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126248 O=C1CC(=C(c2ccccc2)c2ccccc2)C(=O)N1CCCCN1CCN(CC1)c1ccccc1 InChI=1S/C31H33N3O2/c35-29-24-28(30(25-12-4-1-5-13-25)26-14-6-2-7-15-26)31(36)34(29)19-11-10-18-32-20-22-33(23-21-32)27-16-8-3-9-17-27/h1-9,12-17H,10-11,18-24H2 QFESFPVBIJPECI-UHFFFAOYSA-N 50069261 3-Benzhydrylidene-1-[4-(4-phenyl-piperazin-1-yl)-butyl]-pyrrolidine-2,5-dione::CHEMBL342995::cid_9511286 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069261&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9511286 103963369 CHEMBL342995 ZINC08398997 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126252 Clc1cccc(c1)N1CCN(CCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C30H30ClN3O2/c31-25-13-7-14-26(21-25)33-19-17-32(18-20-33)15-8-16-34-28(35)22-27(30(34)36)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-7,9-14,21H,8,15-20,22H2 LLGZHXKYLRDRCB-UHFFFAOYSA-N 50069264 3-Benzhydrylidene-1-{3-[4-(3-chloro-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL358580 D(2) dopamine receptor Rattus norvegicus 801 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069264&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9511277 103963372 CHEMBL358580 ZINC08398990 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126259 Clc1cccc(c1)N1CCN(CCCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C31H32ClN3O2/c32-26-14-9-15-27(22-26)34-20-18-33(19-21-34)16-7-8-17-35-29(36)23-28(31(35)37)30(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-6,9-15,22H,7-8,16-21,23H2 ROGAOFMHAQAPFV-UHFFFAOYSA-N 59418 1-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-3-(diphenylmethylene)pyrrolidine-2,5-dione;hydrochloride::1-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]-3-(diphenylmethylidene)pyrrolidine-2,5-dione;hydrochloride::1-{4-[4-(3-chlorophenyl)-1-piperazinyl]butyl}-3-(diphenylmethylene)-2,5-pyrrolidinedione::3-benzhydrylidene-1-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]pyrrolidine-2,5-dione;hydrochloride::3-benzhydrylidene-1-[4-[4-(3-chlorophenyl)piperazino]butyl]pyrrolidine-2,5-quinone;hydrochloride::CHEMBL356965::MLS000538136::SMR000161527::cid_11948776 D(2) dopamine receptor Rattus norvegicus 367 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=59418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=59418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4557684 252639054 CHEMBL356965 ZINC08399005 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126264 FC(F)(F)c1cccc(c1)N1CCN(CN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C29H26F3N3O2/c30-29(31,32)23-12-7-13-24(18-23)34-16-14-33(15-17-34)20-35-26(36)19-25(28(35)37)27(21-8-3-1-4-9-21)22-10-5-2-6-11-22/h1-13,18H,14-17,19-20H2 HECJDRZLPLNMAE-UHFFFAOYSA-N 50069257 3-Benzhydrylidene-1-[4-(3-trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL148114 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9983639 103963365 CHEMBL148114 ZINC27554036 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126265 FC(F)(F)c1cccc(c1)N1CCN(CN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C29H24F3N3O2/c30-29(31,32)19-6-5-7-20(16-19)34-14-12-33(13-15-34)18-35-26(36)17-25(28(35)37)27-23-10-3-1-8-21(23)22-9-2-4-11-24(22)27/h1-11,16H,12-15,17-18H2 WSPLHQNUHCCVNS-UHFFFAOYSA-N 50072877 3-Fluoren-9-ylidene-1-[4-(3-trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL144372 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072877&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10839198 103966468 CHEMBL144372 ZINC13782630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126270 Fc1ccc(cc1)N1CCN(CN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C28H24FN3O2/c29-19-9-11-20(12-10-19)31-15-13-30(14-16-31)18-32-26(33)17-25(28(32)34)27-23-7-3-1-5-21(23)22-6-2-4-8-24(22)27/h1-12H,13-18H2 FAPBSSIWIMZBNO-UHFFFAOYSA-N 50072886 3-Fluoren-9-ylidene-1-[4-(4-fluoro-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL144294 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072886&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10551639 103966477 CHEMBL144294 ZINC13782642 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126271 COc1ccccc1N1CCN(CCCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C32H35N3O3/c1-38-29-17-9-8-16-28(29)34-22-20-33(21-23-34)18-10-11-19-35-30(36)24-27(32(35)37)31(25-12-4-2-5-13-25)26-14-6-3-7-15-26/h2-9,12-17H,10-11,18-24H2,1H3 ZCMZZNFJNSIGCM-UHFFFAOYSA-N 50069249 3-Benzhydrylidene-1-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL144157 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4673621 103963357 CHEMBL144157 ZINC08399000 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126275 Fc1ccc(cc1)N1CCN(CCCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C30H28FN3O2/c31-21-10-12-22(13-11-21)33-18-16-32(17-19-33)14-5-15-34-28(35)20-27(30(34)36)29-25-8-3-1-6-23(25)24-7-2-4-9-26(24)29/h1-4,6-13H,5,14-20H2 SXQSGPCTXZOSBC-UHFFFAOYSA-N 50072892 3-Fluoren-9-ylidene-1-{3-[4-(4-fluoro-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL341663 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072892&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10767104 103966483 CHEMBL341663 ZINC13782635 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126276 Fc1ccc(cc1)N1CCN(CN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C28H26FN3O2/c29-23-11-13-24(14-12-23)31-17-15-30(16-18-31)20-32-26(33)19-25(28(32)34)27(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-14H,15-20H2 FZPIMABHDJIBBC-UHFFFAOYSA-N 50069267 3-Benzhydrylidene-1-[4-(4-fluoro-phenyl)-piperazin-1-ylmethyl]-pyrrolidine-2,5-dione::CHEMBL357687 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069267&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10479162 103963375 CHEMBL357687 ZINC13782626 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126278 O=C1CC(C(=O)N1CCCCN1CCN(CC1)c1ccccc1)=C1c2ccccc2-c2ccccc12 InChI=1S/C31H31N3O2/c35-29-22-28(30-26-14-6-4-12-24(26)25-13-5-7-15-27(25)30)31(36)34(29)17-9-8-16-32-18-20-33(21-19-32)23-10-2-1-3-11-23/h1-7,10-15H,8-9,16-22H2 ZIGPGWVBSBYKAD-UHFFFAOYSA-N 50072891 3-Fluoren-9-ylidene-1-[4-(4-phenyl-piperazin-1-yl)-butyl]-pyrrolidine-2,5-dione::CHEMBL408681 D(2) dopamine receptor Rattus norvegicus 397.0 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072891&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9511293 103966482 CHEMBL408681 ZINC08399008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126282 FC(F)(F)c1cccc(c1)N1CCN(CCCN2C(=O)CC(=C(c3ccccc3)c3ccccc3)C2=O)CC1 InChI=1S/C31H30F3N3O2/c32-31(33,34)25-13-7-14-26(21-25)36-19-17-35(18-20-36)15-8-16-37-28(38)22-27(30(37)39)29(23-9-3-1-4-10-23)24-11-5-2-6-12-24/h1-7,9-14,21H,8,15-20,22H2 FBICEOFMWBPEIA-UHFFFAOYSA-N 50069259 3-Benzhydrylidene-1-{3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-propyl}-pyrrolidine-2,5-dione::CHEMBL144498 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069259&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10626124 103963367 CHEMBL144498 ZINC27551384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126288 FC(F)(F)c1cccc(c1)N1CCN(CCN2C(=O)CC(C2=O)=C2c3ccccc3-c3ccccc23)CC1 InChI=1S/C30H26F3N3O2/c31-30(32,33)20-6-5-7-21(18-20)35-15-12-34(13-16-35)14-17-36-27(37)19-26(29(36)38)28-24-10-3-1-8-22(24)23-9-2-4-11-25(23)28/h1-11,18H,12-17,19H2 HRFPUBXGMCAEFM-UHFFFAOYSA-N 50072881 3-Fluoren-9-ylidene-1-{2-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-pyrrolidine-2,5-dione::CHEMBL343624 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072881&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10506065 103966472 CHEMBL343624 ZINC13782643 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50574977 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1016/s0960-894x(98)00639-8 10.7270/Q26H4JKD 9934473 Masaguer, CF; Formoso, E; Ravina, E; Tristan, H; Loza, MI; Rivas, E; Fontenla, JA Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50574984 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 263 ChEMBL 10.1016/s0960-894x(98)00639-8 10.7270/Q26H4JKD 9934473 Masaguer, CF; Formoso, E; Ravina, E; Tristan, H; Loza, MI; Rivas, E; Fontenla, JA Universidad de Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126290 O=C1CC(=C(c2ccccc2)c2ccccc2)C(=O)N1CCCN1CCN(CC1)c1ccccc1 InChI=1S/C30H31N3O2/c34-28-23-27(29(24-11-4-1-5-12-24)25-13-6-2-7-14-25)30(35)33(28)18-10-17-31-19-21-32(22-20-31)26-15-8-3-9-16-26/h1-9,11-16H,10,17-23H2 XPGQLDMKJHVVMR-UHFFFAOYSA-N 50069265 3-Benzhydrylidene-1-[3-(4-phenyl-piperazin-1-yl)-propyl]-pyrrolidine-2,5-dione::CHEMBL144876 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980285e 10.7270/Q2B27TFT 9888831 Lopez-Rodriguez, ML; Morcillo, MJ; Rovat, TK; Fernandez, E; Vicente, B; Sanz, AM; Hernandez, M; Orensanz, L Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069265&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10742822 103963373 CHEMBL144876 ZINC13782632 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50125986 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50125992 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 93 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50125995 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc3c(c2)occc3=O)CC1 InChI=1S/C24H23FN2O4/c25-17-2-4-20-23(14-17)31-26-24(20)16-6-10-27(11-7-16)9-1-12-29-18-3-5-19-21(28)8-13-30-22(19)15-18/h2-5,8,13-16H,1,6-7,9-12H2 IRRPXMUZTPWEPJ-UHFFFAOYSA-N 50072824 7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-chromen-4-one::CHEMBL357035 D(2) dopamine receptor Rattus norvegicus 28.1 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072824&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9823559 103966426 CHEMBL357035 ZINC01893115 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50125996 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc3c(c2)occ(C=O)c3=O)CC1 InChI=1S/C25H23FN2O5/c26-18-2-4-20-23(12-18)33-27-24(20)16-6-9-28(10-7-16)8-1-11-31-19-3-5-21-22(13-19)32-15-17(14-29)25(21)30/h2-5,12-16H,1,6-11H2 KXQSQOALQLSOII-UHFFFAOYSA-N 50072823 7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-4-oxo-4H-chromene-3-carbaldehyde::CHEMBL149412 D(2) dopamine receptor Rattus norvegicus 13.1 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9933466 103966425 CHEMBL149412 ZINC02007418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126003 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 13.7 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126004 OCc1coc2cc(OCCCN3CCC(CC3)C(=O)c3ccc(F)cc3)ccc2c1=O InChI=1S/C25H26FNO5/c26-20-4-2-17(3-5-20)24(29)18-8-11-27(12-9-18)10-1-13-31-21-6-7-22-23(14-21)32-16-19(15-28)25(22)30/h2-7,14,16,18,28H,1,8-13,15H2 VPUQMKNAUIAUNU-UHFFFAOYSA-N 50072820 7-{3-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-propoxy}-3-hydroxymethyl-chromen-4-one::CHEMBL101593 D(2) dopamine receptor Rattus norvegicus 190 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072820&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10320962 103966422 CHEMBL101593 ZINC03813788 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126013 OC(=O)c1coc2cc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)ccc2c1=O InChI=1S/C25H23FN2O6/c26-16-2-4-18-22(12-16)34-27-23(18)15-6-9-28(10-7-15)8-1-11-32-17-3-5-19-21(13-17)33-14-20(24(19)29)25(30)31/h2-5,12-15H,1,6-11H2,(H,30,31) CBYQZVHEBOKXCG-UHFFFAOYSA-N 50072825 7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-4-oxo-4H-chromene-3-carboxylic acid::CHEMBL347997 D(2) dopamine receptor Rattus norvegicus 12.8 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072825&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9892291 103966427 CHEMBL347997 ZINC02007421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126018 Cc1coc2cc(OCCCN3CCC(CC3)C(=O)c3ccc(F)cc3)ccc2c1=O InChI=1S/C25H26FNO4/c1-17-16-31-23-15-21(7-8-22(23)24(17)28)30-14-2-11-27-12-9-19(10-13-27)25(29)18-3-5-20(26)6-4-18/h3-8,15-16,19H,2,9-14H2,1H3 ZQIDWYHAGMEIHU-UHFFFAOYSA-N 50072827 7-{3-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-propoxy}-3-methyl-chromen-4-one::CHEMBL101076 D(2) dopamine receptor Rattus norvegicus 211 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072827&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10502396 103966429 CHEMBL101076 ZINC01543265 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126031 OCc1coc2cc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)ccc2c1=O InChI=1S/C25H25FN2O5/c26-18-2-4-20-23(12-18)33-27-24(20)16-6-9-28(10-7-16)8-1-11-31-19-3-5-21-22(13-19)32-15-17(14-29)25(21)30/h2-5,12-13,15-16,29H,1,6-11,14H2 ICAXEUYZCLRXKY-UHFFFAOYSA-N 50072822 7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-hydroxymethyl-chromen-4-one::CHEMBL151475 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3037308 103966424 CHEMBL151475 ZINC01893112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126034 COCc1coc2cc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)ccc2c1=O InChI=1S/C26H27FN2O5/c1-31-15-18-16-33-23-14-20(4-6-22(23)26(18)30)32-12-2-9-29-10-7-17(8-11-29)25-21-5-3-19(27)13-24(21)34-28-25/h3-6,13-14,16-17H,2,7-12,15H2,1H3 AWIQJZYUGHZLJB-UHFFFAOYSA-N 50072826 7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxymethyl-chromen-4-one::CHEMBL150412 D(2) dopamine receptor Rattus norvegicus 48.1 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072826&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9804562 103966428 CHEMBL150412 ZINC02007415 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126040 Cc1coc2cc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)ccc2c1=O InChI=1S/C25H25FN2O4/c1-16-15-31-22-14-19(4-6-21(22)25(16)29)30-12-2-9-28-10-7-17(8-11-28)24-20-5-3-18(26)13-23(20)32-27-24/h3-6,13-15,17H,2,7-12H2,1H3 YJKSMRSCQYIHMX-UHFFFAOYSA-N 50072828 7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methyl-chromen-4-one::CHEMBL153626 D(2) dopamine receptor Rattus norvegicus 16.6 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072828&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599046 103966430 CHEMBL153626 ZINC01893117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50126041 OCc1cc(=O)c2ccc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2o1 InChI=1S/C25H25FN2O5/c26-17-2-4-21-24(12-17)33-27-25(21)16-6-9-28(10-7-16)8-1-11-31-18-3-5-20-22(30)13-19(15-29)32-23(20)14-18/h2-5,12-14,16,29H,1,6-11,15H2 RHEDVRGGTUGTPR-UHFFFAOYSA-N 50072821 7-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-2-hydroxymethyl-chromen-4-one::CHEMBL345952 D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm9810396 10.7270/Q2QC02N8 9876110 Bolos, J; Anglada, L; Gubert, S; Planas, JM; Agut, J; Princep, M; De la Fuente, N; Sacristan, A; Ortiz, JA Centro de Investigación Grupo Ferrer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50072821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50072821&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9826827 103966423 CHEMBL345952 ZINC02007426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50124123 O=C1Cc2c(N1)cccc2N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H21N3O/c23-19-13-16-17(20-19)7-4-8-18(16)22-11-9-21(10-12-22)14-15-5-2-1-3-6-15/h1-8H,9-14H2,(H,20,23) TUVRDSTTWFDDHW-UHFFFAOYSA-N 50071856 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-indol-2-one::CHEMBL314952 D(2) dopamine receptor Rattus norvegicus 0.560000 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9995379 103965566 CHEMBL314952 ZINC26639952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50124140 Clc1ccc2NC(=O)Cc2c1N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H20ClN3O/c20-16-6-7-17-15(12-18(24)21-17)19(16)23-10-8-22(9-11-23)13-14-4-2-1-3-5-14/h1-7H,8-13H2,(H,21,24) PIPVZEXRFVHTJJ-UHFFFAOYSA-N 50071859 4-(4-Benzyl-piperazin-1-yl)-5-chloro-1,3-dihydro-indol-2-one::CHEMBL330108 D(2) dopamine receptor Rattus norvegicus 85 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323780 103965569 CHEMBL330108 ZINC26645609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127395 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C(c1ccccc1)c1ccccc1 InChI=1S/C28H29N5O3/c1-35-23-17-21-22(18-24(23)36-2)30-28(31-26(21)29)33-15-13-32(14-16-33)27(34)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,17-18,25H,13-16H2,1-2H3,(H2,29,30,31) DGUCMTZXMJORQA-UHFFFAOYSA-N 50073560 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2,2-diphenyl-ethanone::CHEMBL342200 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10767175 103966922 CHEMBL342200 ZINC00601646 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127406 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C(C)(C)Oc1c(OC)cccc1C(C)C InChI=1S/C28H37N5O5/c1-17(2)18-9-8-10-21(35-5)24(18)38-28(3,4)26(34)32-11-13-33(14-12-32)27-30-20-16-23(37-7)22(36-6)15-19(20)25(29)31-27/h8-10,15-17H,11-14H2,1-7H3,(H2,29,30,31) RAMKRNRAZRVJGG-UHFFFAOYSA-N 50073562 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2-isopropyl-6-methoxy-phenoxy)-2-methyl-propan-1-one::CHEMBL435591 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10625876 103966924 CHEMBL435591 ZINC13782859 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127419 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)COc1c(OC)cccc1C(C)C InChI=1S/C26H33N5O5/c1-16(2)17-7-6-8-20(33-3)24(17)36-15-23(32)30-9-11-31(12-10-30)26-28-19-14-22(35-5)21(34-4)13-18(19)25(27)29-26/h6-8,13-14,16H,9-12,15H2,1-5H3,(H2,27,28,29) ZZMFJJDBKSYGRM-UHFFFAOYSA-N 50057463 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2-isopropyl-6-methoxy-phenoxy)-ethanone::CHEMBL430717 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057463&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9891980 103953515 CHEMBL430717 ZINC00602525 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127421 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(c1ccccc1)c1ccccc1 InChI=1S/C27H29N5O2/c1-33-23-17-21-22(18-24(23)34-2)29-27(30-26(21)28)32-15-13-31(14-16-32)25(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,17-18,25H,13-16H2,1-2H3,(H2,28,29,30) YQLQTQMHZRZKKJ-UHFFFAOYSA-N 50073558 2-(4-Benzhydryl-piperazin-1-yl)-6,7-dimethoxy-quinazolin-4-ylamine::CHEMBL136482 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10837477 103966920 CHEMBL136482 ZINC13782861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127428 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C(C)Oc1c(OC)cccc1C(C)C InChI=1S/C27H35N5O5/c1-16(2)18-8-7-9-21(34-4)24(18)37-17(3)26(33)31-10-12-32(13-11-31)27-29-20-15-23(36-6)22(35-5)14-19(20)25(28)30-27/h7-9,14-17H,10-13H2,1-6H3,(H2,28,29,30) XLJAXHKXAQXROY-UHFFFAOYSA-N 50073559 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2-isopropyl-6-methoxy-phenoxy)-propan-1-one::CHEMBL136458 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10577609 103966921 CHEMBL136458 ZINC13782858 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127433 COc1cccc(OC)c1OCC(=O)N1CCN(CC1)c1nc(N)c2cc(OC)c(OC)cc2n1 InChI=1S/C24H29N5O6/c1-31-17-6-5-7-18(32-2)22(17)35-14-21(30)28-8-10-29(11-9-28)24-26-16-13-20(34-4)19(33-3)12-15(16)23(25)27-24/h5-7,12-13H,8-11,14H2,1-4H3,(H2,25,26,27) TVKDDIPFFFMLKI-UHFFFAOYSA-N 50073566 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2,6-dimethoxy-phenoxy)-ethanone::CHEMBL335731 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10790988 103966928 CHEMBL335731 ZINC03939113 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127434 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(C)=O InChI=1S/C16H21N5O3/c1-10(22)20-4-6-21(7-5-20)16-18-12-9-14(24-3)13(23-2)8-11(12)15(17)19-16/h8-9H,4-7H2,1-3H3,(H2,17,18,19) RYPUHXSUCBWYDG-UHFFFAOYSA-N 50073564 1-(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)ethanone::1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-ethanone::CHEMBL136561 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1504973 103966926 CHEMBL136561 ZINC01424240 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127442 COc1cc2nc(nc(N)c2cc1OC)N1CCC(CC1)(c1ccccc1)c1ccccc1 InChI=1S/C27H28N4O2/c1-32-23-17-21-22(18-24(23)33-2)29-26(30-25(21)28)31-15-13-27(14-16-31,19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,17-18H,13-16H2,1-2H3,(H2,28,29,30) AZNDJFDHVWENRU-UHFFFAOYSA-N 50073578 2-(4,4-Diphenyl-piperidin-1-yl)-6,7-dimethoxy-quinazolin-4-ylamine::CHEMBL136067 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10503257 103966940 CHEMBL136067 ZINC13782867 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127448 COc1ccc(C[C@@H](C)Nc2nc(N)c3cc(OC)c(OC)cc3n2)cc1S(N)(=O)=O InChI=1S/C20H25N5O5S/c1-11(7-12-5-6-15(28-2)18(8-12)31(22,26)27)23-20-24-14-10-17(30-4)16(29-3)9-13(14)19(21)25-20/h5-6,8-11H,7H2,1-4H3,(H2,22,26,27)(H3,21,23,24,25)/t11-/m1/s1 QIIBGPIFAIVPTJ-LLVKDONJSA-N 50073577 5-[(R)-2-(4-Amino-6,7-dimethoxy-quinazolin-2-ylamino)-propyl]-2-methoxy-benzenesulfonamide::CHEMBL136375 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073577&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10813325 103966939 CHEMBL136375 ZINC13782865 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127453 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)CCC(=O)c1ccccc1 InChI=1S/C24H27N5O4/c1-32-20-14-17-18(15-21(20)33-2)26-24(27-23(17)25)29-12-10-28(11-13-29)22(31)9-8-19(30)16-6-4-3-5-7-16/h3-7,14-15H,8-13H2,1-2H3,(H2,25,26,27) FTDBTBLFOYBMNU-UHFFFAOYSA-N 50073573 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-4-phenyl-butane-1,4-dione::CHEMBL424658 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10575494 103966935 CHEMBL424658 ZINC00601650 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127457 COc1cc2nc(nc(N)c2cc1OC)N1CC[N+]([O-])(Cc2ccccc2)CC1 InChI=1S/C21H25N5O3/c1-28-18-12-16-17(13-19(18)29-2)23-21(24-20(16)22)25-8-10-26(27,11-9-25)14-15-6-4-3-5-7-15/h3-7,12-13H,8-11,14H2,1-2H3,(H2,22,23,24) MTBVCRHRERRCTQ-UHFFFAOYSA-N 50073579 2-(4-Benzyl-4-oxy-piperazin-1-yl)-6,7-dimethoxy-quinazolin-4-ylamine::CHEMBL136426 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073579&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10786873 103966941 CHEMBL136426 ZINC27440417 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127461 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)CC(=O)c1ccccc1 InChI=1S/C23H25N5O4/c1-31-19-12-16-17(13-20(19)32-2)25-23(26-22(16)24)28-10-8-27(9-11-28)21(30)14-18(29)15-6-4-3-5-7-15/h3-7,12-13H,8-11,14H2,1-2H3,(H2,24,25,26) PXWNTBGUQKWMOQ-UHFFFAOYSA-N 50073556 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-3-phenyl-propane-1,3-dione::CHEMBL434228 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9867616 103966918 CHEMBL434228 ZINC00600636 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127462 COc1cc2nc(nc(N)c2cc1OC)N1CCN(Cc2ccccc2)CC1 InChI=1S/C21H25N5O2/c1-27-18-12-16-17(13-19(18)28-2)23-21(24-20(16)22)26-10-8-25(9-11-26)14-15-6-4-3-5-7-15/h3-7,12-13H,8-11,14H2,1-2H3,(H2,22,23,24) JABYAVHSPNMUGH-UHFFFAOYSA-N 50073576 2-(4-Benzyl-piperazin-1-yl)-6,7-dimethoxy-quinazolin-4-ylamine::CHEMBL342671 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10714748 103966938 CHEMBL342671 ZINC13782860 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127474 COc1cc2nc(nc(N)c2cc1OC)N1CCNCC1 InChI=1S/C14H19N5O2/c1-20-11-7-9-10(8-12(11)21-2)17-14(18-13(9)15)19-5-3-16-4-6-19/h7-8,16H,3-6H2,1-2H3,(H2,15,17,18) APKHJGDGWQDBGM-UHFFFAOYSA-N 50073568 6,7-Dimethoxy-2-piperazin-1-yl-quinazolin-4-ylamine::Aminodimethoxyquinazolinylpiperazine (piperazine derivative of terazosin)::CHEMBL1226::cid_616267 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 0EC 2LWK 616267 103966930 CHEMBL1226 ZINC00203311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127479 COc1cc2nc(nc(N)c2cc1OC)N(C)CCC(c1ccccc1)c1ccccc1 InChI=1S/C26H28N4O2/c1-30(15-14-20(18-10-6-4-7-11-18)19-12-8-5-9-13-19)26-28-22-17-24(32-3)23(31-2)16-21(22)25(27)29-26/h4-13,16-17,20H,14-15H2,1-3H3,(H2,27,28,29) BLUONAREVSMXCN-UHFFFAOYSA-N 50073569 CHEMBL136123::N*2*-(3,3-Diphenyl-propyl)-6,7-dimethoxy-N*2*-methyl-quinazoline-2,4-diamine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10598639 103966931 CHEMBL136123 ZINC13782864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127492 COc1cc2nc(nc(NC(C)=O)c2cc1OC)N1CCN(CC1)C(C)=O InChI=1S/C18H23N5O4/c1-11(24)19-17-13-9-15(26-3)16(27-4)10-14(13)20-18(21-17)23-7-5-22(6-8-23)12(2)25/h9-10H,5-8H2,1-4H3,(H,19,20,21,24) BLNRJCOAQFRNAD-UHFFFAOYSA-N 50073561 CHEMBL136627::N-[2-(4-Acetyl-piperazin-1-yl)-6,7-dimethoxy-quinazolin-4-yl]-acetamide D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11793720 103966923 CHEMBL136627 ZINC13782852 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127502 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccccc1 InChI=1S/C21H23N5O3/c1-28-17-12-15-16(13-18(17)29-2)23-21(24-19(15)22)26-10-8-25(9-11-26)20(27)14-6-4-3-5-7-14/h3-7,12-13H,8-11H2,1-2H3,(H2,22,23,24) ZZSVTGUBKHVPCL-UHFFFAOYSA-N 50073580 (4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(phenyl)methanone::CHEMBL123128::[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-phenyl-methanone D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073580&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10691966 103966942 CHEMBL123128 ZINC13782854 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127507 COc1ccccc1OCC(=O)N1CCN(CC1)c1nc(N)c2cc(OC)c(OC)cc2n1 InChI=1S/C23H27N5O5/c1-30-17-6-4-5-7-18(17)33-14-21(29)27-8-10-28(11-9-27)23-25-16-13-20(32-3)19(31-2)12-15(16)22(24)26-23/h4-7,12-13H,8-11,14H2,1-3H3,(H2,24,25,26) LPHYFVMMGUVREO-UHFFFAOYSA-N 50073565 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2-methoxy-phenoxy)-ethanone::CHEMBL343283 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10575664 103966927 CHEMBL343283 ZINC13782855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127512 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)OCc1ccccc1 InChI=1S/C21H25N5O3/c1-27-18-12-16-17(13-19(18)28-2)23-21(24-20(16)22)25-8-10-26(11-9-25)29-14-15-6-4-3-5-7-15/h3-7,12-13H,8-11,14H2,1-2H3,(H2,22,23,24) IJKMIKFXTRSWDR-UHFFFAOYSA-N 50073557 2-(4-Benzyloxy-piperazin-1-yl)-6,7-dimethoxy-quinazolin-4-ylamine::CHEMBL337371 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10763248 103966919 CHEMBL337371 ZINC13782862 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127517 COc1cc2nc(nc(N)c2cc1OC)N1CCc2ccccc2C1 InChI=1S/C19H20N4O2/c1-24-16-9-14-15(10-17(16)25-2)21-19(22-18(14)20)23-8-7-12-5-3-4-6-13(12)11-23/h3-6,9-10H,7-8,11H2,1-2H3,(H2,20,21,22) AMHBGRVKWJLMMP-UHFFFAOYSA-N 50073575 2-(3,4-Dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinazolin-4-ylamine::CHEMBL136684 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10664606 103966937 CHEMBL136684 ZINC13782866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127518 COc1cc2CCN(Cc2cc1OC)c1nc(N)c2cc(OC)c(OC)cc2n1 InChI=1S/C21H24N4O4/c1-26-16-7-12-5-6-25(11-13(12)8-17(16)27-2)21-23-15-10-19(29-4)18(28-3)9-14(15)20(22)24-21/h7-10H,5-6,11H2,1-4H3,(H2,22,23,24) RQCHWAFNIYJAAP-UHFFFAOYSA-N 50073567 2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxy-quinazolin-4-ylamine::CHEMBL344178 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9978046 103966929 CHEMBL344178 ZINC13782868 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127519 COc1cc2nc(nc(N)c2cc1OC)N1CCc2c(C1)ccc1ccccc21 InChI=1S/C23H22N4O2/c1-28-20-11-18-19(12-21(20)29-2)25-23(26-22(18)24)27-10-9-17-15(13-27)8-7-14-5-3-4-6-16(14)17/h3-8,11-12H,9-10,13H2,1-2H3,(H2,24,25,26) DSUCOQWPXQJBBD-UHFFFAOYSA-N 50073572 2-(1,4-Dihydro-2H-benzo[f]isoquinolin-3-yl)-6,7-dimethoxy-quinazolin-4-ylamine::CHEMBL343364 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10643878 103966934 CHEMBL343364 ZINC00601652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127521 COc1ccccc1OC(C)(C)C(=O)N1CCN(CC1)c1nc(N)c2cc(OC)c(OC)cc2n1 InChI=1S/C25H31N5O5/c1-25(2,35-19-9-7-6-8-18(19)32-3)23(31)29-10-12-30(13-11-29)24-27-17-15-21(34-5)20(33-4)14-16(17)22(26)28-24/h6-9,14-15H,10-13H2,1-5H3,(H2,26,27,28) NWZXZNWTMRLUCS-UHFFFAOYSA-N 50073581 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2-(2-methoxy-phenoxy)-2-methyl-propan-1-one::CHEMBL137679 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10719565 103966943 CHEMBL137679 ZINC13782856 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127524 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)c1ccco1 InChI=1S/C18H21N5O3/c1-24-14-10-12-13(11-15(14)25-2)20-18(21-17(12)19)23-7-5-22(6-8-23)16-4-3-9-26-16/h3-4,9-11H,5-8H2,1-2H3,(H2,19,20,21) WESSELXZMWZPLT-UHFFFAOYSA-N 50073570 2-(4-Furan-2-yl-piperazin-1-yl)-6,7-dimethoxy-quinazolin-4-ylamine::CHEMBL137598 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20215436 103966932 CHEMBL137598 ZINC27436263 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127536 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C(C)(C)C InChI=1S/C19H27N5O3/c1-19(2,3)17(25)23-6-8-24(9-7-23)18-21-13-11-15(27-5)14(26-4)10-12(13)16(20)22-18/h10-11H,6-9H2,1-5H3,(H2,20,21,22) QNIFPINTTFMXRU-UHFFFAOYSA-N 50073574 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-2,2-dimethyl-propan-1-one::CHEMBL136060 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10571401 103966936 CHEMBL136060 ZINC13782853 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127542 COc1cc2nc(nc(N)c2cc1OC)N(C)Cc1ccccc1 InChI=1S/C18H20N4O2/c1-22(11-12-7-5-4-6-8-12)18-20-14-10-16(24-3)15(23-2)9-13(14)17(19)21-18/h4-10H,11H2,1-3H3,(H2,19,20,21) VHFBRYIVMQCGQD-UHFFFAOYSA-N 50073571 CHEMBL136588::N*2*-Benzyl-6,7-dimethoxy-N*2*-methyl-quinazoline-2,4-diamine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10734775 103966933 CHEMBL136588 ZINC13782863 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127546 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)CC(c1ccccc1)c1ccccc1 InChI=1S/C29H31N5O3/c1-36-25-17-23-24(19-26(25)37-2)31-29(32-28(23)30)34-15-13-33(14-16-34)27(35)18-22(20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,17,19,22H,13-16,18H2,1-2H3,(H2,30,31,32) OQDVCLJHYBLHNT-UHFFFAOYSA-N 50073563 1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piperazin-1-yl]-3,3-diphenyl-propan-1-one::CHEMBL137903 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm9805337 10.7270/Q2FN15CK 9986714 Leonardi, A; Motta, G; Boi, C; Testa, R; Poggesi, E; De Benedetti, PG; Menziani, MC Recordati S.p.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10256583 103966925 CHEMBL137903 ZINC00601647 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127552 COc1cccc2[C@H](CCCc12)NCCCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H35N3O2/c1-29-24-13-6-8-20-21(24)9-5-10-22(20)26-14-7-15-27-16-18-28(19-17-27)23-11-3-4-12-25(23)30-2/h3-4,6,8,11-13,22,26H,5,7,9-10,14-19H2,1-2H3/t22-/m0/s1 JQDKIHJGQVYOCG-QFIPXVFZSA-N 50073611 CHEMBL147692::{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-((S)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine D(2) dopamine receptor Rattus norvegicus 2300 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073611&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692893 103966945 CHEMBL147692 ZINC13757351 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127555 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C25H34N2O2/c1-28-24-14-6-10-21-20(8-5-11-22(21)24)9-7-15-26-16-18-27(19-17-26)23-12-3-4-13-25(23)29-2/h3-4,6,10,12-14,20H,5,7-9,11,15-19H2,1-2H3 INGWKGCHJJYQIB-UHFFFAOYSA-N 50033839 1-(2-Methoxy-phenyl)-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL26929 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10385977 103942087 CHEMBL26929 ZINC13740674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127556 COc1cccc2[C@@H](CCCc12)NCCN1CCN(CC1)c1ccccc1OC InChI=1S/C24H33N3O2/c1-28-23-12-6-7-19-20(23)8-5-9-21(19)25-13-14-26-15-17-27(18-16-26)22-10-3-4-11-24(22)29-2/h3-4,6-7,10-12,21,25H,5,8-9,13-18H2,1-2H3/t21-/m1/s1 FVDGLILSFMGSJG-OAQYLSRUSA-N 50073612 CHEMBL147371::{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine D(2) dopamine receptor Rattus norvegicus 3200 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073612&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692100 103966946 CHEMBL147371 ZINC22937544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127557 COc1cccc2C(CCCc12)NC(=O)CCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H33N3O3/c1-30-23-12-6-7-19-20(23)8-5-9-21(19)26-25(29)13-14-27-15-17-28(18-16-27)22-10-3-4-11-24(22)31-2/h3-4,6-7,10-12,21H,5,8-9,13-18H2,1-2H3,(H,26,29) HGOXUQUWFDSTAA-UHFFFAOYSA-N 50052563 3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propionamide::CHEMBL28063::N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propanamide D(2) dopamine receptor Rattus norvegicus 761 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740969 103949415 CHEMBL28063 ZINC13586504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127559 COc1cccc2[C@@H](CCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C25H34N2O2/c1-28-24-14-6-10-21-20(8-5-11-22(21)24)9-7-15-26-16-18-27(19-17-26)23-12-3-4-13-25(23)29-2/h3-4,6,10,12-14,20H,5,7-9,11,15-19H2,1-2H3/t20-/m1/s1 INGWKGCHJJYQIB-HXUWFJFHSA-N 50073614 1-(2-Methoxy-phenyl)-4-[3-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL144523 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10715665 103966948 CHEMBL144523 ZINC13740673 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127568 COc1cccc2C(CCCc12)NCCCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H35N3O2/c1-29-24-13-6-8-20-21(24)9-5-10-22(20)26-14-7-15-27-16-18-28(19-17-27)23-11-3-4-12-25(23)30-2/h3-4,6,8,11-13,22,26H,5,7,9-10,14-19H2,1-2H3 JQDKIHJGQVYOCG-UHFFFAOYSA-N 50052569 CHEMBL107486::{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine D(2) dopamine receptor Rattus norvegicus 1060 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669248 103949421 CHEMBL107486 ZINC13757354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127572 COc1cccc2[C@H](CCCN3CCN(CC3)c3ccccc3)CCCc12 InChI=1S/C24H32N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h2-4,6,10-12,14,20H,5,7-9,13,15-19H2,1H3/t20-/m0/s1 JGCUFOXBUYJGBX-FQEVSTJZSA-N 50073620 1-[3-((S)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL147861 D(2) dopamine receptor Rattus norvegicus 610 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073620&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594965 103966954 CHEMBL147861 ZINC13740694 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127574 COc1cccc2[C@H](CCCc12)NC(=O)CCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H33N3O3/c1-30-23-12-6-7-19-20(23)8-5-9-21(19)26-25(29)13-14-27-15-17-28(18-16-27)22-10-3-4-11-24(22)31-2/h3-4,6-7,10-12,21H,5,8-9,13-18H2,1-2H3,(H,26,29)/t21-/m0/s1 HGOXUQUWFDSTAA-NRFANRHFSA-N 50073616 3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-((S)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propionamide::CHEMBL435029 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073616&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10812216 103966950 CHEMBL435029 ZINC13586503 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127577 COc1cccc2[C@@H](CCCN3CCN(CC3)c3ccccc3)CCCc12 InChI=1S/C24H32N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h2-4,6,10-12,14,20H,5,7-9,13,15-19H2,1H3/t20-/m1/s1 JGCUFOXBUYJGBX-HXUWFJFHSA-N 50073610 1-[3-((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL147963 D(2) dopamine receptor Rattus norvegicus 880 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073610&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618792 103966944 CHEMBL147963 ZINC13740693 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127579 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3)CCCc12 InChI=1S/C24H32N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h2-4,6,10-12,14,20H,5,7-9,13,15-19H2,1H3 JGCUFOXBUYJGBX-UHFFFAOYSA-N 50033857 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL322275 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10361439 103942105 CHEMBL322275 ZINC13740694 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127583 COc1cccc2[C@@H](CCCc12)NCCCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H35N3O2/c1-29-24-13-6-8-20-21(24)9-5-10-22(20)26-14-7-15-27-16-18-28(19-17-27)23-11-3-4-12-25(23)30-2/h3-4,6,8,11-13,22,26H,5,7,9-10,14-19H2,1-2H3/t22-/m1/s1 JQDKIHJGQVYOCG-JOCHJYFZSA-N 50073619 CHEMBL148397::{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine D(2) dopamine receptor Rattus norvegicus 1900 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073619&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10597660 103966953 CHEMBL148397 ZINC13757354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127584 COc1cccc2[C@H](CCCN3CCN(CC3)c3ccccn3)CCCc12 InChI=1S/C23H31N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-3,5,9,11-13,19H,4,6-8,10,14-18H2,1H3/t19-/m0/s1 KKPMYWNQZNRGIK-IBGZPJMESA-N 50073617 1-[3-((S)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL148288 D(2) dopamine receptor Rattus norvegicus 600 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10361497 103966951 CHEMBL148288 ZINC13470658 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127586 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.06 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127588 COc1cccc2C(CCCc12)NCCN1CCN(CC1)c1ccccc1OC InChI=1S/C24H33N3O2/c1-28-23-12-6-7-19-20(23)8-5-9-21(19)25-13-14-26-15-17-27(18-16-26)22-10-3-4-11-24(22)29-2/h3-4,6-7,10-12,21,25H,5,8-9,13-18H2,1-2H3 FVDGLILSFMGSJG-UHFFFAOYSA-N 50033847 CHEMBL108241::{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine D(2) dopamine receptor Rattus norvegicus 380 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10453320 103942095 CHEMBL108241 ZINC22937544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127597 COc1cccc2[C@@H](CCCN3CCN(CC3)c3ccccn3)CCCc12 InChI=1S/C23H31N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-3,5,9,11-13,19H,4,6-8,10,14-18H2,1H3/t19-/m1/s1 KKPMYWNQZNRGIK-LJQANCHMSA-N 50073613 1-[3-((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL148186 D(2) dopamine receptor Rattus norvegicus 880 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073613&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11793238 103966947 CHEMBL148186 ZINC13470656 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127599 COc1cccc2C(CCCN3CCN(CC3)c3ccccn3)CCCc12 InChI=1S/C23H31N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-3,5,9,11-13,19H,4,6-8,10,14-18H2,1H3 KKPMYWNQZNRGIK-UHFFFAOYSA-N 50033852 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL444590 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10474042 103942100 CHEMBL444590 ZINC13470658 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127600 COc1cccc2[C@@H](CCCc12)NC(=O)CCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H33N3O3/c1-30-23-12-6-7-19-20(23)8-5-9-21(19)26-25(29)13-14-27-15-17-28(18-16-27)22-10-3-4-11-24(22)31-2/h3-4,6-7,10-12,21H,5,8-9,13-18H2,1-2H3,(H,26,29)/t21-/m1/s1 HGOXUQUWFDSTAA-OAQYLSRUSA-N 50073618 3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propionamide::CHEMBL359245 D(2) dopamine receptor Rattus norvegicus 870 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10764762 103966952 CHEMBL359245 ZINC13586504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127606 COc1cccc2[C@H](CCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C25H34N2O2/c1-28-24-14-6-10-21-20(8-5-11-22(21)24)9-7-15-26-16-18-27(19-17-26)23-12-3-4-13-25(23)29-2/h3-4,6,10,12-14,20H,5,7-9,11,15-19H2,1-2H3/t20-/m0/s1 INGWKGCHJJYQIB-FQEVSTJZSA-N 50073621 1-(2-Methoxy-phenyl)-4-[3-((S)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL147659 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073621&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10500865 103966955 CHEMBL147659 ZINC13740674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50127607 COc1cccc2[C@H](CCCc12)NCCN1CCN(CC1)c1ccccc1OC InChI=1S/C24H33N3O2/c1-28-23-12-6-7-19-20(23)8-5-9-21(19)25-13-14-26-15-17-27(18-16-26)22-10-3-4-11-24(22)29-2/h3-4,6-7,10-12,21,25H,5,8-9,13-18H2,1-2H3/t21-/m0/s1 FVDGLILSFMGSJG-NRFANRHFSA-N 50073615 CHEMBL148234::{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-((S)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine D(2) dopamine receptor Rattus norvegicus 650 ChEMBL 10.1021/jm980420n 10.7270/Q29W0DP9 9986719 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073615&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10786888 103966949 CHEMBL148234 ZINC22937541 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135712 O=C1N(CCCCN2CCC(C2)c2ccccc2)S(=O)(=O)c2ccccc12 InChI=1S/C21H24N2O3S/c24-21-19-10-4-5-11-20(19)27(25,26)23(21)14-7-6-13-22-15-12-18(16-22)17-8-2-1-3-9-17/h1-5,8-11,18H,6-7,12-16H2 YRBNPVDPNYJOMH-UHFFFAOYSA-N 50077658 1,1-Dioxo-2-[4-(3-phenyl-pyrrolidin-1-yl)-butyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one::CHEMBL28831 D(2) dopamine receptor Rattus norvegicus 195 ChEMBL 10.1016/s0960-894x(99)00201-2 10.7270/Q2862FMC 10360740 Ahn, KH; Lee, SJ; Lee, CH; Hong, CY; Park, TK POSTECH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077658&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10068602 103970423 CHEMBL28831 ZINC13913408 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135714 Clc1ccc(cc1)C1CCN(CCCCN2Cc3ccccc3C2=O)C1 InChI=1S/C22H25ClN2O/c23-20-9-7-17(8-10-20)18-11-14-24(15-18)12-3-4-13-25-16-19-5-1-2-6-21(19)22(25)26/h1-2,5-10,18H,3-4,11-16H2 DITXJRIVUJRJED-UHFFFAOYSA-N 50077660 2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-2,3-dihydro-isoindol-1-one::CHEMBL28884 D(2) dopamine receptor Rattus norvegicus 185 ChEMBL 10.1016/s0960-894x(99)00201-2 10.7270/Q2862FMC 10360740 Ahn, KH; Lee, SJ; Lee, CH; Hong, CY; Park, TK POSTECH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077660&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44278267 103970425 CHEMBL28884 ZINC28770228 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135717 O=C(N1CCCCC1)c1cccc(CN2CCC(C2)c2ccccc2)c1 InChI=1S/C23H28N2O/c26-23(25-13-5-2-6-14-25)21-11-7-8-19(16-21)17-24-15-12-22(18-24)20-9-3-1-4-10-20/h1,3-4,7-11,16,22H,2,5-6,12-15,17-18H2 GSDNUWIKENUUCL-UHFFFAOYSA-N 50077659 CHEMBL281214::[3-(3-Phenyl-pyrrolidin-1-ylmethyl)-phenyl]-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 783 ChEMBL 10.1016/s0960-894x(99)00201-2 10.7270/Q2862FMC 10360740 Ahn, KH; Lee, SJ; Lee, CH; Hong, CY; Park, TK POSTECH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077659&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44278298 103970424 CHEMBL281214 ZINC28769958 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135720 Fc1ccc(cc1)C1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)C1 InChI=1S/C21H23FN2O3S/c22-18-9-7-16(8-10-18)17-11-14-23(15-17)12-3-4-13-24-21(25)19-5-1-2-6-20(19)28(24,26)27/h1-2,5-10,17H,3-4,11-15H2 LIWHJGHRCCCSFT-UHFFFAOYSA-N 50077664 2-{4-[3-(4-Fluoro-phenyl)-pyrrolidin-1-yl]-butyl}-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one::CHEMBL417661 D(2) dopamine receptor Rattus norvegicus 263 ChEMBL 10.1016/s0960-894x(99)00201-2 10.7270/Q2862FMC 10360740 Ahn, KH; Lee, SJ; Lee, CH; Hong, CY; Park, TK POSTECH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077664&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10363751 103970429 CHEMBL417661 ZINC13913409 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135722 Clc1ccc(cc1)C1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)C1 InChI=1S/C21H23ClN2O3S/c22-18-9-7-16(8-10-18)17-11-14-23(15-17)12-3-4-13-24-21(25)19-5-1-2-6-20(19)28(24,26)27/h1-2,5-10,17H,3-4,11-15H2 IATFGLZNNVFTIY-UHFFFAOYSA-N 50077661 2-{4-[3-(4-Chloro-phenyl)-pyrrolidin-1-yl]-butyl}-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one::CHEMBL28946 D(2) dopamine receptor Rattus norvegicus 327 ChEMBL 10.1016/s0960-894x(99)00201-2 10.7270/Q2862FMC 10360740 Ahn, KH; Lee, SJ; Lee, CH; Hong, CY; Park, TK POSTECH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077661&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44278409 103970426 CHEMBL28946 ZINC28770171 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135736 O=C1N(CCCCN2CCC(C2)c2ccccc2)Cc2ccccc12 InChI=1S/C22H26N2O/c25-22-21-11-5-4-10-20(21)17-24(22)14-7-6-13-23-15-12-19(16-23)18-8-2-1-3-9-18/h1-5,8-11,19H,6-7,12-17H2 ILQNTXCJQDSEDV-UHFFFAOYSA-N 50077662 2-[4-(3-Phenyl-pyrrolidin-1-yl)-butyl]-2,3-dihydro-isoindol-1-one::CHEMBL282822 D(2) dopamine receptor Rattus norvegicus 77 ChEMBL 10.1016/s0960-894x(99)00201-2 10.7270/Q2862FMC 10360740 Ahn, KH; Lee, SJ; Lee, CH; Hong, CY; Park, TK POSTECH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077662&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44278364 103970427 CHEMBL282822 ZINC28769818 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135745 Clc1ccc(cc1)C1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)C1 InChI=1S/C23H27ClN2O/c24-22-9-7-19(8-10-22)21-11-14-25(17-21)16-18-5-4-6-20(15-18)23(27)26-12-2-1-3-13-26/h4-10,15,21H,1-3,11-14,16-17H2 QGXORMKPUWUKLI-UHFFFAOYSA-N 50077663 CHEMBL280534::{3-[3-(4-Chloro-phenyl)-pyrrolidin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 334 ChEMBL 10.1016/s0960-894x(99)00201-2 10.7270/Q2862FMC 10360740 Ahn, KH; Lee, SJ; Lee, CH; Hong, CY; Park, TK POSTECH http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077663&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44278297 103970428 CHEMBL280534 ZINC28769954 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137279 Nc1ccc(cc1)C#CCCN1CCC(Cc2ccc(F)cc2)CC1 InChI=1S/C22H25FN2/c23-21-8-4-19(5-9-21)17-20-12-15-25(16-13-20)14-2-1-3-18-6-10-22(24)11-7-18/h4-11,20H,2,12-17,24H2 SBPJSDPAXDUZCO-UHFFFAOYSA-N 50078474 4-{4-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-but-1-ynyl}-phenylamine::CHEMBL81167 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10806801 103971025 CHEMBL81167 ZINC13798584 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137282 Nc1ccc(cc1)C#CCCN1CCC(O)(Cc2ccccc2)CC1 InChI=1S/C22H26N2O/c23-21-11-9-19(10-12-21)6-4-5-15-24-16-13-22(25,14-17-24)18-20-7-2-1-3-8-20/h1-3,7-12,25H,5,13-18,23H2 ISVKCDBNGIPSLZ-UHFFFAOYSA-N 50078478 1-[4-(4-Amino-phenyl)-but-3-ynyl]-4-benzyl-piperidin-4-ol::CHEMBL311062 D(2) dopamine receptor Rattus norvegicus 15000 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078478&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10616737 103971029 CHEMBL311062 ZINC13798586 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137284 NS(=O)(=O)c1ccc(cc1)C#CCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C22H26N2O2S/c23-27(25,26)22-11-9-19(10-12-22)6-4-5-15-24-16-13-21(14-17-24)18-20-7-2-1-3-8-20/h1-3,7-12,21H,5,13-18H2,(H2,23,25,26) VIOYTEZUBLWNPQ-UHFFFAOYSA-N 50078477 4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-benzenesulfonamide::CHEMBL82498 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078477&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809938 103971028 CHEMBL82498 ZINC13798571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137288 Nc1ccc(cc1N)C#CCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C22H27N3/c23-21-10-9-19(17-22(21)24)8-4-5-13-25-14-11-20(12-15-25)16-18-6-2-1-3-7-18/h1-3,6-7,9-10,17,20H,5,11-16,23-24H2 SYYKYYJFGJHYGB-UHFFFAOYSA-N 50078483 4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-benzene-1,2-diamine::CHEMBL310632 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10830499 103971034 CHEMBL310632 ZINC13798578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137296 CNc1ccc(cc1)C#CCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C23H28N2/c1-24-23-12-10-20(11-13-23)7-5-6-16-25-17-14-22(15-18-25)19-21-8-3-2-4-9-21/h2-4,8-13,22,24H,6,14-19H2,1H3 LQHMXMOZTNJDHD-UHFFFAOYSA-N 50078488 CHEMBL309737::{4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenyl}-methyl-amine D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10496831 103971039 CHEMBL309737 ZINC03827655 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137300 CS(=O)(=O)Nc1ccc(cc1)C#CCN1CCC(Cc2ccccc2)CC1 InChI=1S/C22H26N2O2S/c1-27(25,26)23-22-11-9-19(10-12-22)8-5-15-24-16-13-21(14-17-24)18-20-6-3-2-4-7-20/h2-4,6-7,9-12,21,23H,13-18H2,1H3 XUIIEFRDBMIDAY-UHFFFAOYSA-N 50078492 CHEMBL312721::N-{4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenyl}-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 12000 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078492&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10833784 103971043 CHEMBL312721 ZINC13798604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137311 CS(=O)(=O)Nc1ccc(cc1)C#CCCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C24H30N2O2S/c1-29(27,28)25-24-13-11-21(12-14-24)8-6-3-7-17-26-18-15-23(16-19-26)20-22-9-4-2-5-10-22/h2,4-5,9-14,23,25H,3,7,15-20H2,1H3 XWPWPHKNLRCSOK-UHFFFAOYSA-N 50078476 CHEMBL79668::N-{4-[5-(4-Benzyl-piperidin-1-yl)-pent-1-ynyl]-phenyl}-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 2300 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078476&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645264 103971027 CHEMBL79668 ZINC13798607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137312 CC(=O)Nc1ccc(cc1)C#CCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C24H28N2O/c1-20(27)25-24-12-10-21(11-13-24)7-5-6-16-26-17-14-23(15-18-26)19-22-8-3-2-4-9-22/h2-4,8-13,23H,6,14-19H2,1H3,(H,25,27) XRVOIGOCEXMZCZ-UHFFFAOYSA-N 50078491 CHEMBL83938::N-{4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenyl}-acetamide D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078491&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10737263 103971042 CHEMBL83938 ZINC03952619 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137316 NCc1cccc(c1)C#CCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C23H28N2/c24-19-23-11-6-10-21(18-23)9-4-5-14-25-15-12-22(13-16-25)17-20-7-2-1-3-8-20/h1-3,6-8,10-11,18,22H,5,12-17,19,24H2 JRBBEWSIXBWGPM-UHFFFAOYSA-N 50078499 3-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-benzylamine::CHEMBL314015 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078499&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10759007 103971050 CHEMBL314015 ZINC13798574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137319 Cc1ccc(CC2CCN(CCC#Cc3ccc(N)cc3)CC2)cc1 InChI=1S/C23H28N2/c1-19-5-7-21(8-6-19)18-22-13-16-25(17-14-22)15-3-2-4-20-9-11-23(24)12-10-20/h5-12,22H,3,13-18,24H2,1H3 YPBXVUBCNUFOIU-UHFFFAOYSA-N 50078473 4-{4-[4-(4-Methyl-benzyl)-piperidin-1-yl]-but-1-ynyl}-phenylamine::CHEMBL83958 D(2) dopamine receptor Rattus norvegicus 800 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9797682 103971024 CHEMBL83958 ZINC03827654 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137320 Oc1ccc(cc1)C#CCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C22H25NO/c24-22-11-9-19(10-12-22)6-4-5-15-23-16-13-21(14-17-23)18-20-7-2-1-3-8-20/h1-3,7-12,21,24H,5,13-18H2 DQZBYMUDSJTGLY-UHFFFAOYSA-N 50078480 4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenol::CHEMBL83781 D(2) dopamine receptor Rattus norvegicus 290 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078480&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10426105 103971031 CHEMBL83781 ZINC03952618 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137336 Cc1ccc(CC2(O)CCN(CCC#Cc3ccc(N)cc3)CC2)cc1 InChI=1S/C23H28N2O/c1-19-5-7-21(8-6-19)18-23(26)13-16-25(17-14-23)15-3-2-4-20-9-11-22(24)12-10-20/h5-12,26H,3,13-18,24H2,1H3 GYXQIQUDONKGID-UHFFFAOYSA-N 50078489 1-[4-(4-Amino-phenyl)-but-3-ynyl]-4-(4-methyl-benzyl)-piperidin-4-ol::CHEMBL84227 D(2) dopamine receptor Rattus norvegicus 10000 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078489&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10760169 103971040 CHEMBL84227 ZINC13798592 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137353 CS(=O)(=O)Nc1ccc(cc1)C#CCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C23H28N2O2S/c1-28(26,27)24-23-12-10-20(11-13-23)7-5-6-16-25-17-14-22(15-18-25)19-21-8-3-2-4-9-21/h2-4,8-13,22,24H,6,14-19H2,1H3 RZOQAAQWMIFUOZ-UHFFFAOYSA-N 50078497 CHEMBL84043::N-{4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenyl}-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10715785 103971048 CHEMBL84043 ZINC13798560 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137356 Nc1ccc(cc1)C#CCCN1CCC(Cc2ccccc2)CC1 InChI=1S/C22H26N2/c23-22-11-9-19(10-12-22)6-4-5-15-24-16-13-21(14-17-24)18-20-7-2-1-3-8-20/h1-3,7-12,21H,5,13-18,23H2 ZBDREQAUXIWPPQ-UHFFFAOYSA-N 50078500 4-(4-(4-benzylpiperidin-1-yl)but-1-ynyl)aniline::4-[4-(4-Benzyl-piperidin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL83218 D(2) dopamine receptor Rattus norvegicus 800 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078500&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10710707 103971051 CHEMBL83218 ZINC03827651 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137371 Oc1ccc(cc1)C#CCN1CCC(Cc2ccccc2)CC1 InChI=1S/C21H23NO/c23-21-10-8-18(9-11-21)7-4-14-22-15-12-20(13-16-22)17-19-5-2-1-3-6-19/h1-3,5-6,8-11,20,23H,12-17H2 YZFVGINTZAFMNW-UHFFFAOYSA-N 50078498 4-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-phenol::CHEMBL79904 D(2) dopamine receptor Rattus norvegicus 1700 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078498&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10756990 103971049 CHEMBL79904 ZINC12356083 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136397 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136405 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C19H18F3N3O4S/c1-24-8-10-25(11-9-24)18-14-12-13(29-30(26,27)19(20,21)22)6-7-16(14)28-17-5-3-2-4-15(17)23-18/h2-7,12H,8-11H2,1H3 DQNCRNVCBHYBQP-UHFFFAOYSA-N 50078062 CHEMBL430798::Trifluoro-methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepin-2-yl ester D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078062&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10026300 103970697 CHEMBL430798 ZINC14299682 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50137392 Nc1ccc(cc1)C#CCCN1CCC(O)(Cc2ccc(F)cc2)CC1 InChI=1S/C22H25FN2O/c23-20-8-4-19(5-9-20)17-22(26)12-15-25(16-13-22)14-2-1-3-18-6-10-21(24)11-7-18/h4-11,26H,2,12-17,24H2 DNDXMHMLUZVSPN-UHFFFAOYSA-N 50078490 1-[4-(4-Amino-phenyl)-but-3-ynyl]-4-(4-fluoro-benzyl)-piperidin-4-ol::CHEMBL312384 D(2) dopamine receptor Rattus norvegicus 79000 ChEMBL 10.1021/jm990148x 10.7270/Q24B30H5 10395488 Wright, JL; Gregory, TF; Bigge, CF; Boxer, PA; Serpa, K; Meltzer, LT; Wise, LD; Cai, SX; Hawkinson, JE; Konkoy, CS; Whittemore, ER; Woodward, RM; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078490&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10617994 103971041 CHEMBL312384 ZINC13798589 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136415 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(O)cc12 InChI=1S/C18H20N4O/c1-21-8-10-22(11-9-21)18-14-12-13(23)6-7-15(14)19-16-4-2-3-5-17(16)20-18/h2-7,12,19,23H,8-11H2,1H3 KBSRARKSRVWNEC-UHFFFAOYSA-N 50061556 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-ol::CHEMBL308090 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10828627 103957118 CHEMBL308090 ZINC13775874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136418 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C19H19F3N4O3S/c1-25-8-10-26(11-9-25)18-14-12-13(29-30(27,28)19(20,21)22)6-7-15(14)23-16-4-2-3-5-17(16)24-18/h2-7,12,23H,8-11H2,1H3 XKXPMSXRABANAG-UHFFFAOYSA-N 50061559 CHEMBL72292::Trifluoro-methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-yl ester D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9954899 103957121 CHEMBL72292 ZINC14299681 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136438 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 7.5 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136443 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C19H18ClF3N4O3S/c1-26-6-8-27(9-7-26)18-14-11-13(30-31(28,29)19(21,22)23)3-5-15(14)24-16-4-2-12(20)10-17(16)25-18/h2-5,10-11,24H,6-9H2,1H3 MTKHCEFATKQYMK-UHFFFAOYSA-N 50078063 CHEMBL70319::Trifluoro-methanesulfonic acid 8-chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-yl ester D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078063&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10412646 103970698 CHEMBL70319 ZINC14114286 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136444 COc1ccc2Nc3ccccc3N=C(N3CCN(C)CC3)c2c1 InChI=1S/C19H22N4O/c1-22-9-11-23(12-10-22)19-15-13-14(24-2)7-8-16(15)20-17-5-3-4-6-18(17)21-19/h3-8,13,20H,9-12H2,1-2H3 NXWRIBLQJIVCRL-UHFFFAOYSA-N 50061558 2-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL72794 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15521599 103957120 CHEMBL72794 ZINC13775872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136453 CN1CCN(CC1)C1=Nc2cc(O)ccc2Nc2ccccc12 InChI=1S/C18H20N4O/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-15(14)19-16-7-6-13(23)12-17(16)20-18/h2-7,12,19,23H,8-11H2,1H3 JLYQCLIQUFEFFL-UHFFFAOYSA-N 50061557 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-ol::CHEMBL70377 D(2) dopamine receptor Rattus norvegicus 6400 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 475251 103957119 CHEMBL70377 ZINC13775875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136467 CN1CCN(CC1)C1=Nc2ccccc2Sc2ccc(OS(=O)(=O)C(F)(F)F)cc12 InChI=1S/C19H18F3N3O3S2/c1-24-8-10-25(11-9-24)18-14-12-13(28-30(26,27)19(20,21)22)6-7-16(14)29-17-5-3-2-4-15(17)23-18/h2-7,12H,8-11H2,1H3 PZIGTEKDSRHYIT-UHFFFAOYSA-N 50078061 CHEMBL73589::Trifluoro-methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepin-2-yl ester D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078061&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10049758 103970696 CHEMBL73589 ZINC14299683 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136469 COc1ccc2Nc3ccccc3C(=Nc2c1)N1CCN(C)CC1 InChI=1S/C19H22N4O/c1-22-9-11-23(12-10-22)19-15-5-3-4-6-16(15)20-17-8-7-14(24-2)13-18(17)21-19/h3-8,13,20H,9-12H2,1-2H3 VTMVQXBSLJXPIT-UHFFFAOYSA-N 50061555 8-Methoxy-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL73074 D(2) dopamine receptor Rattus norvegicus 4300 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061555&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15521598 103957117 CHEMBL73074 ZINC53150568 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136473 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(OS(C)(=O)=O)cc12 InChI=1S/C19H22N4O3S/c1-22-9-11-23(12-10-22)19-15-13-14(26-27(2,24)25)7-8-16(15)20-17-5-3-4-6-18(17)21-19/h3-8,13,20H,9-12H2,1-2H3 OUTHAVMRGGWPSK-UHFFFAOYSA-N 50078066 CHEMBL307163::Methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-yl ester D(2) dopamine receptor Rattus norvegicus 920 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078066&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24121307 103970701 CHEMBL307163 ZINC26377519 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136480 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 330 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136489 CN1CCN(CC1)C1=Nc2cc(OS(C)(=O)=O)ccc2Nc2ccccc12 InChI=1S/C19H22N4O3S/c1-22-9-11-23(12-10-22)19-15-5-3-4-6-16(15)20-17-8-7-14(13-18(17)21-19)26-27(2,24)25/h3-8,13,20H,9-12H2,1-2H3 CCMSWCPOSSFEQM-UHFFFAOYSA-N 50078065 CHEMBL70609::Methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-yl ester D(2) dopamine receptor Rattus norvegicus 33000 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50078065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50078065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10548209 103970700 CHEMBL70609 ZINC13798269 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50136503 CN1CCN(CC1)C1=Nc2cc(OS(=O)(=O)C(F)(F)F)ccc2Nc2ccccc12 InChI=1S/C19H19F3N4O3S/c1-25-8-10-26(11-9-25)18-14-4-2-3-5-15(14)23-16-7-6-13(12-17(16)24-18)29-30(27,28)19(20,21)22/h2-7,12,23H,8-11H2,1H3 RDPIPNDQCUEYHW-UHFFFAOYSA-N 50061560 CHEMBL310712::Trifluoro-methanesulfonic acid 11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-yl ester D(2) dopamine receptor Rattus norvegicus 8100 ChEMBL 10.1021/jm991005d 10.7270/Q2KH0MH7 10377229 Liao, Y; Venhuis, BJ; Rodenhuis, N; Timmerman, W; Wikstrom, H; Meier, E; Bartoszyk, GD; Bottcher, H; Seyfried, CA; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10575100 103957122 CHEMBL310712 ZINC36238019 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135445 Oc1ccc2CC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m1/s1 DWUAAOIZQFTYQP-MRXNPFEDSA-N 50061669 (R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL134807::CHEMBL64553 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378389 103957219 CHEMBL134807CHEMBL64553 ZINC13527706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135450 Clc1ccc(OCCNCc2cccs2)c2CC(=O)Nc12 InChI=1S/C15H15ClN2O2S/c16-12-3-4-13(11-8-14(19)18-15(11)12)20-6-5-17-9-10-2-1-7-21-10/h1-4,7,17H,5-6,8-9H2,(H,18,19) MXDAPRHGJIKJMQ-UHFFFAOYSA-N 50077565 7-Chloro-4-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-1,3-dihydro-indol-2-one::CHEMBL60548 D(2) dopamine receptor Rattus norvegicus 3.9 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10663658 103970334 CHEMBL60548 ZINC26161855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135452 C(NCc1ccccc1)[C@H]1CCc2ccc3[nH]ccc3c2O1 InChI=1S/C19H20N2O/c1-2-4-14(5-3-1)12-20-13-16-8-6-15-7-9-18-17(10-11-21-18)19(15)22-16/h1-5,7,9-11,16,20-21H,6,8,12-13H2/t16-/m1/s1 AERWLNZHDGJKMO-MRXNPFEDSA-N 50077569 Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]indol-2-yl)methyl]-amine::CHEMBL60185 D(2) dopamine receptor Rattus norvegicus 36 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10613605 103970338 CHEMBL60185 ZINC12356074 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135453 Fc1ccc(OCCN2CCc3ccccc3C2)c2CC(=O)Nc12 InChI=1S/C19H19FN2O2/c20-16-5-6-17(15-11-18(23)21-19(15)16)24-10-9-22-8-7-13-3-1-2-4-14(13)12-22/h1-6H,7-12H2,(H,21,23) UFPMVMHWBPUCTK-UHFFFAOYSA-N 50077570 4-[2-(3,4-Dihydro-1H-isoquinolin-2-yl)-ethoxy]-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL291459 D(2) dopamine receptor Rattus norvegicus 0.860000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10592220 103970339 CHEMBL291459 ZINC26162337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135454 Oc1ccc2OC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C16H17NO3/c18-13-6-7-15-16(8-13)20-14(11-19-15)10-17-9-12-4-2-1-3-5-12/h1-8,14,17-18H,9-11H2/t14-/m0/s1 DYWYWIOQKKRAST-AWEZNQCLSA-N 50061642 (S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]dioxin-6-ol; oxalic acid::CHEMBL300571::CHEMBL423890 D(2) dopamine receptor Rattus norvegicus 0.400000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10612157 103957192 CHEMBL300571CHEMBL423890 ZINC13775979 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135459 CN(CCOc1cccc2NC(=O)Cc12)Cc1ccccc1 InChI=1S/C18H20N2O2/c1-20(13-14-6-3-2-4-7-14)10-11-22-17-9-5-8-16-15(17)12-18(21)19-16/h2-9H,10-13H2,1H3,(H,19,21) ZCTQZPVZSXAFAK-UHFFFAOYSA-N 50077568 4-[2-(Benzyl-methyl-amino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL434407 D(2) dopamine receptor Rattus norvegicus 0.760000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10661630 103970337 CHEMBL434407 ZINC00023355 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135461 NCCOc1ccc(F)c2NC(=O)Cc12 InChI=1S/C10H11FN2O2/c11-7-1-2-8(15-4-3-12)6-5-9(14)13-10(6)7/h1-2H,3-5,12H2,(H,13,14) SGAXOBUAZNCOOR-UHFFFAOYSA-N 50077571 4-(2-Amino-ethoxy)-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL302436 D(2) dopamine receptor Rattus norvegicus 916 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10703634 103970340 CHEMBL302436 ZINC26162196 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135464 Fc1ccc(OCCNCCCc2c[nH]c3ccccc23)c2CC(=O)Nc12 InChI=1S/C21H22FN3O2/c22-17-7-8-19(16-12-20(26)25-21(16)17)27-11-10-23-9-3-4-14-13-24-18-6-2-1-5-15(14)18/h1-2,5-8,13,23-24H,3-4,9-12H2,(H,25,26) RTTDUHNRPAYWKJ-UHFFFAOYSA-N 50077577 7-Fluoro-4-{2-[3-(1H-indol-3-yl)-propylamino]-ethoxy}-1,3-dihydro-indol-2-one::CHEMBL60265 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077577&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618968 103970346 CHEMBL60265 ZINC26154052 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135477 NCCOc1cccc2NC(=O)Cc12 InChI=1S/C10H12N2O2/c11-4-5-14-9-3-1-2-8-7(9)6-10(13)12-8/h1-3H,4-6,11H2,(H,12,13) JZOOPCSBOXTVMN-UHFFFAOYSA-N 50077585 4-(2-Amino-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL416856 D(2) dopamine receptor Rattus norvegicus 6.9 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077585&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10583903 103970354 CHEMBL416856 ZINC01903147 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135491 Clc1ccc(OCCN2Cc3ccccc3C2)c2CC(=O)Nc12 InChI=1S/C18H17ClN2O2/c19-15-5-6-16(14-9-17(22)20-18(14)15)23-8-7-21-10-12-3-1-2-4-13(12)11-21/h1-6H,7-11H2,(H,20,22) NTOGEDXEDRMFKP-UHFFFAOYSA-N 50077592 7-Chloro-4-[2-(1,3-dihydro-isoindol-2-yl)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL64524 D(2) dopamine receptor Rattus norvegicus 0.440000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077592&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10853769 103970361 CHEMBL64524 ZINC26163138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135493 Fc1ccc(OCCN2Cc3ccccc3C2)c2CC(=O)Nc12 InChI=1S/C18H17FN2O2/c19-15-5-6-16(14-9-17(22)20-18(14)15)23-8-7-21-10-12-3-1-2-4-13(12)11-21/h1-6H,7-11H2,(H,20,22) AAMLBIYNFUAPCS-UHFFFAOYSA-N 50077573 4-[2-(1,3-Dihydro-isoindol-2-yl)-ethoxy]-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL300316 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10638841 103970342 CHEMBL300316 ZINC26154059 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135495 Cc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1 InChI=1S/C18H19ClN2O2/c1-12-2-4-13(5-3-12)11-20-8-9-23-16-7-6-15(19)18-14(16)10-17(22)21-18/h2-7,20H,8-11H2,1H3,(H,21,22) GZDWJPMFRZBGFX-UHFFFAOYSA-N 50077591 7-Chloro-4-[2-(4-methyl-benzylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL305585 D(2) dopamine receptor Rattus norvegicus 0.640000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10711537 103970360 CHEMBL305585 ZINC26149429 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135496 Clc1c[nH]c2c(Cl)ccc(OCCNCc3ccc(Cl)cc3)c12 InChI=1S/C17H15Cl3N2O/c18-12-3-1-11(2-4-12)9-21-7-8-23-15-6-5-13(19)17-16(15)14(20)10-22-17/h1-6,10,21-22H,7-9H2 ZCVWXRHTDZMYSR-UHFFFAOYSA-N 50077595 (4-Chloro-benzyl)-[2-(3,7-dichloro-1H-indol-4-yloxy)-ethyl]-amine::CHEMBL60361 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9799480 103970364 CHEMBL60361 ZINC01903134 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135512 Fc1ccc(OCCNCc2ccccc2)c2CC(=O)Nc12 InChI=1S/C17H17FN2O2/c18-14-6-7-15(13-10-16(21)20-17(13)14)22-9-8-19-11-12-4-2-1-3-5-12/h1-7,19H,8-11H2,(H,20,21) OSMFCZGZJMRMAV-UHFFFAOYSA-N 50077597 4-(2-Benzylamino-ethoxy)-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL63491 D(2) dopamine receptor Rattus norvegicus 0.630000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077597&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10732973 103970366 CHEMBL63491 ZINC26165582 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135514 Oc1ccc2NC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C16H18N2O2/c19-13-6-7-15-16(8-13)20-14(11-18-15)10-17-9-12-4-2-1-3-5-12/h1-8,14,17-19H,9-11H2/t14-/m0/s1 OFRVVOZORYSDMF-AWEZNQCLSA-N 50077584 (S)-2-(Benzylamino-methyl)-3,4-dihydro-2H-benzo[1,4]oxazin-7-ol::CHEMBL59992 D(2) dopamine receptor Rattus norvegicus 6.7 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077584&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44303196 103970353 CHEMBL59992 ZINC13798062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135516 CN(CCCC(=O)c1ccc(F)cc1)CCOc1cccc2NC(=O)Cc12 InChI=1S/C21H23FN2O3/c1-24(11-3-5-19(25)15-7-9-16(22)10-8-15)12-13-27-20-6-2-4-18-17(20)14-21(26)23-18/h2,4,6-10H,3,5,11-14H2,1H3,(H,23,26) IOVXZPKVVVPHDX-UHFFFAOYSA-N 50077586 4-(2-{[4-(4-Fluoro-phenyl)-4-oxo-butyl]-methyl-amino}-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL60900 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10714219 103970355 CHEMBL60900 ZINC26158976 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135517 Fc1ccc(OCCNCc2ccc(cc2)-c2ccccc2)c2CC(=O)Nc12 InChI=1S/C23H21FN2O2/c24-20-10-11-21(19-14-22(27)26-23(19)20)28-13-12-25-15-16-6-8-18(9-7-16)17-4-2-1-3-5-17/h1-11,25H,12-15H2,(H,26,27) PLXCESBDIJXCGL-UHFFFAOYSA-N 50077590 4-{2-[(Biphenyl-4-ylmethyl)-amino]-ethoxy}-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL64798 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077590&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10547536 103970359 CHEMBL64798 ZINC26165572 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135520 Fc1ccc(OCCNCc2ccsc2)c2CC(=O)Nc12 InChI=1S/C15H15FN2O2S/c16-12-1-2-13(11-7-14(19)18-15(11)12)20-5-4-17-8-10-3-6-21-9-10/h1-3,6,9,17H,4-5,7-8H2,(H,18,19) YPZRCWNVQVKPJX-UHFFFAOYSA-N 50077600 7-Fluoro-4-{2-[(thiophen-3-ylmethyl)-amino]-ethoxy}-1,3-dihydro-indol-2-one::CHEMBL418510 D(2) dopamine receptor Rattus norvegicus 0.840000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077600&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10662428 103970369 CHEMBL418510 ZINC29570361 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135525 O=C1Cc2c(N1)ccc1CC[C@H](CNCc3ccccc3)Oc21 InChI=1S/C19H20N2O2/c22-18-10-16-17(21-18)9-7-14-6-8-15(23-19(14)16)12-20-11-13-4-2-1-3-5-13/h1-5,7,9,15,20H,6,8,10-12H2,(H,21,22)/t15-/m1/s1 NPATVCXCHCPFCB-OAHLLOKOSA-N 50077581 (R)-2-(Benzylamino-methyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indol-8-one::CHEMBL303556 D(2) dopamine receptor Rattus norvegicus 0.140000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10063875 103970350 CHEMBL303556 ZINC13586902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135528 Clc1c[nH]c2cccc(OCCNCCCCc3ccccc3)c12 InChI=1S/C20H23ClN2O/c21-17-15-23-18-10-6-11-19(20(17)18)24-14-13-22-12-5-4-9-16-7-2-1-3-8-16/h1-3,6-8,10-11,15,22-23H,4-5,9,12-14H2 MYZONUPBZFDODL-UHFFFAOYSA-N 50077563 CHEMBL64420::[2-(3-Chloro-1H-indol-4-yloxy)-ethyl]-(4-phenyl-butyl)-amine D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9884480 103970332 CHEMBL64420 ZINC01903137 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135544 Fc1ccc(OCCNCC2CCCCC2)c2CC(=O)Nc12 InChI=1S/C17H23FN2O2/c18-14-6-7-15(13-10-16(21)20-17(13)14)22-9-8-19-11-12-4-2-1-3-5-12/h6-7,12,19H,1-5,8-11H2,(H,20,21) IWPODTZOHNIYFY-UHFFFAOYSA-N 50077587 4-[2-(Cyclohexylmethyl-amino)-ethoxy]-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL59750 D(2) dopamine receptor Rattus norvegicus 0.650000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10757042 103970356 CHEMBL59750 ZINC26162345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135552 CCCCNCCOc1ccc(Cl)c2NC(=O)Cc12 InChI=1S/C14H19ClN2O2/c1-2-3-6-16-7-8-19-12-5-4-11(15)14-10(12)9-13(18)17-14/h4-5,16H,2-3,6-9H2,1H3,(H,17,18) UGVNNOUXZAJBHJ-UHFFFAOYSA-N 50077583 4-(2-Butylamino-ethoxy)-7-chloro-1,3-dihydro-indol-2-one::CHEMBL304894 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077583&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10802894 103970352 CHEMBL304894 ZINC26162397 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135556 FC(F)(F)C(=O)c1c[nH]c2c(Cl)ccc(OCCNCc3ccccc3)c12 InChI=1S/C19H16ClF3N2O2/c20-14-6-7-15(27-9-8-24-10-12-4-2-1-3-5-12)16-13(11-25-17(14)16)18(26)19(21,22)23/h1-7,11,24-25H,8-10H2 QBNVFACVZPZVHG-UHFFFAOYSA-N 50077594 1-[4-(2-Benzylamino-ethoxy)-7-chloro-1H-indol-3-yl]-2,2,2-trifluoro-ethanone::CHEMBL60840 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9908760 103970363 CHEMBL60840 ZINC01903140 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135557 Clc1ccc(OCCNCc2ccccc2)c2cc[nH]c12 InChI=1S/C17H17ClN2O/c18-15-6-7-16(14-8-9-20-17(14)15)21-11-10-19-12-13-4-2-1-3-5-13/h1-9,19-20H,10-12H2 VWVPMNHCCNZAGX-UHFFFAOYSA-N 50077596 Benzyl-[2-(7-chloro-1H-indol-4-yloxy)-ethyl]-amine::CHEMBL64134 D(2) dopamine receptor Rattus norvegicus 7.4 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077596&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9839319 103970365 CHEMBL64134 ZINC01903129 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135558 Clc1ccc(OCCNCc2ccccc2)c2CC(=O)Nc12 InChI=1S/C17H17ClN2O2/c18-14-6-7-15(13-10-16(21)20-17(13)14)22-9-8-19-11-12-4-2-1-3-5-12/h1-7,19H,8-11H2,(H,20,21) MBLREOGMGHDMJH-UHFFFAOYSA-N 50077572 4-(2-Benzylamino-ethoxy)-7-chloro-1,3-dihydro-indol-2-one::CHEMBL435182 D(2) dopamine receptor Rattus norvegicus 0.410000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10313715 103970341 CHEMBL435182 ZINC26150459 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135560 C(CCc1ccccc1)CNCCOc1cccc2[nH]ccc12 InChI=1S/C20H24N2O/c1-2-7-17(8-3-1)9-4-5-13-21-15-16-23-20-11-6-10-19-18(20)12-14-22-19/h1-3,6-8,10-12,14,21-22H,4-5,9,13,15-16H2 XLIMGWVIUMZMMX-UHFFFAOYSA-N 50077588 CHEMBL59737::[2-(1H-Indol-4-yloxy)-ethyl]-(4-phenyl-butyl)-amine D(2) dopamine receptor Rattus norvegicus 5.3 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077588&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9861435 103970357 CHEMBL59737 ZINC01903127 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135563 Clc1ccc(OCCNc2ccc3ccccc3c2)c2CC(=O)Nc12 InChI=1S/C20H17ClN2O2/c21-17-7-8-18(16-12-19(24)23-20(16)17)25-10-9-22-15-6-5-13-3-1-2-4-14(13)11-15/h1-8,11,22H,9-10,12H2,(H,23,24) FDCFNYCBHMWNKL-UHFFFAOYSA-N 50077566 7-Chloro-4-[2-(naphthalen-2-ylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL294538 D(2) dopamine receptor Rattus norvegicus 6.3 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10831870 103970335 CHEMBL294538 ZINC26168210 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135564 O=C1Cc2c(N1)cccc2OCCNCCCCc1ccccc1 InChI=1S/C20H24N2O2/c23-20-15-17-18(22-20)10-6-11-19(17)24-14-13-21-12-5-4-9-16-7-2-1-3-8-16/h1-3,6-8,10-11,21H,4-5,9,12-15H2,(H,22,23) PTTJRNUQRLBAEV-UHFFFAOYSA-N 50077602 4-[2-(4-Phenyl-butylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL61671 D(2) dopamine receptor Rattus norvegicus 2.1 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10520031 103970371 CHEMBL61671 ZINC26150427 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135567 Fc1ccc(OCCNCc2cccs2)c2CC(=O)Nc12 InChI=1S/C15H15FN2O2S/c16-12-3-4-13(11-8-14(19)18-15(11)12)20-6-5-17-9-10-2-1-7-21-10/h1-4,7,17H,5-6,8-9H2,(H,18,19) JRUPYTLRKHUREA-UHFFFAOYSA-N 50077582 7-Fluoro-4-{2-[(thiophen-2-ylmethyl)-amino]-ethoxy}-1,3-dihydro-indol-2-one::CHEMBL64574 D(2) dopamine receptor Rattus norvegicus 0.660000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077582&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10638352 103970351 CHEMBL64574 ZINC26163010 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135572 Fc1ccc(CNCCOc2ccc(Cl)c3[nH]cc(Cl)c23)cc1 InChI=1S/C17H15Cl2FN2O/c18-13-5-6-15(16-14(19)10-22-17(13)16)23-8-7-21-9-11-1-3-12(20)4-2-11/h1-6,10,21-22H,7-9H2 GEHFGDHALWGGMK-UHFFFAOYSA-N 50077564 CHEMBL64345::[2-(3,7-Dichloro-1H-indol-4-yloxy)-ethyl]-(4-fluoro-benzyl)-amine D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9884884 103970333 CHEMBL64345 ZINC01903132 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135574 Fc1ccc(OCCNc2ccc3ccccc3c2)c2CC(=O)Nc12 InChI=1S/C20H17FN2O2/c21-17-7-8-18(16-12-19(24)23-20(16)17)25-10-9-22-15-6-5-13-3-1-2-4-14(13)11-15/h1-8,11,22H,9-10,12H2,(H,23,24) SHSCMNFGMPWQKM-UHFFFAOYSA-N 50077601 7-Fluoro-4-[2-(naphthalen-2-ylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL62290 D(2) dopamine receptor Rattus norvegicus 9 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640595 103970370 CHEMBL62290 ZINC26168709 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135580 Clc1ccc(OCCN2CCc3ccccc3CC2)c2CC(=O)Nc12 InChI=1S/C20H21ClN2O2/c21-17-5-6-18(16-13-19(24)22-20(16)17)25-12-11-23-9-7-14-3-1-2-4-15(14)8-10-23/h1-6H,7-13H2,(H,22,24) DZAIXMOGMCWKEV-UHFFFAOYSA-N 50077574 7-Chloro-4-[2-(1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL292253 D(2) dopamine receptor Rattus norvegicus 4.3 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44303541 103970343 CHEMBL292253 ZINC26168677 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135589 CNCCOc1cccc2NC(=O)Cc12 InChI=1S/C11H14N2O2/c1-12-5-6-15-10-4-2-3-9-8(10)7-11(14)13-9/h2-4,12H,5-7H2,1H3,(H,13,14) STMJSLDMROVPBX-UHFFFAOYSA-N 50077567 4-(2-Methylamino-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL64238 D(2) dopamine receptor Rattus norvegicus 147 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10822156 103970336 CHEMBL64238 ZINC01903146 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135593 Clc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1 InChI=1S/C17H16Cl2N2O2/c18-12-3-1-11(2-4-12)10-20-7-8-23-15-6-5-14(19)17-13(15)9-16(22)21-17/h1-6,20H,7-10H2,(H,21,22) JPSMZWRPAFVXDX-UHFFFAOYSA-N 50077604 7-Chloro-4-[2-(4-chloro-benzylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL302000 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077604&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10498102 103970373 CHEMBL302000 ZINC26163145 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135594 FC(F)(F)C(=O)c1c[nH]c2cccc(OCCNCc3ccccc3)c12 InChI=1S/C19H17F3N2O2/c20-19(21,22)18(25)14-12-24-15-7-4-8-16(17(14)15)26-10-9-23-11-13-5-2-1-3-6-13/h1-8,12,23-24H,9-11H2 NQQDGDDHTBBKPN-UHFFFAOYSA-N 50077589 1-[4-(2-Benzylamino-ethoxy)-1H-indol-3-yl]-2,2,2-trifluoro-ethanone::CHEMBL60783 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077589&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9928915 103970358 CHEMBL60783 ZINC01903125 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135595 Fc1ccc(CNCCOc2ccc(Cl)c3NC(=O)Cc23)cc1 InChI=1S/C17H16ClFN2O2/c18-14-5-6-15(13-9-16(22)21-17(13)14)23-8-7-20-10-11-1-3-12(19)4-2-11/h1-6,20H,7-10H2,(H,21,22) LYCHDJRJSBEWKP-UHFFFAOYSA-N 50077599 7-Chloro-4-[2-(4-fluoro-benzylamino)-ethoxy]-1,3-dihydro-indol-2-one::CHEMBL59500 D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077599&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10544736 103970368 CHEMBL59500 ZINC29570546 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135597 O=C1Cc2c(N1)cccc2OCCNCc1ccccc1 InChI=1S/C17H18N2O2/c20-17-11-14-15(19-17)7-4-8-16(14)21-10-9-18-12-13-5-2-1-3-6-13/h1-8,18H,9-12H2,(H,19,20) CVWQKEFTSSJDLS-UHFFFAOYSA-N 50077578 4-(2-Benzylamino-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL59752 D(2) dopamine receptor Rattus norvegicus 0.210000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903877 103970347 CHEMBL59752 ZINC01903144 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135599 Clc1ccc(OCCNCc2ccc(cc2)-c2ccccc2)c2CC(=O)Nc12 InChI=1S/C23H21ClN2O2/c24-20-10-11-21(19-14-22(27)26-23(19)20)28-13-12-25-15-16-6-8-18(9-7-16)17-4-2-1-3-5-17/h1-11,25H,12-15H2,(H,26,27) XJSQDZJJAFIJPV-UHFFFAOYSA-N 50077598 4-{2-[(Biphenyl-4-ylmethyl)-amino]-ethoxy}-7-chloro-1,3-dihydro-indol-2-one::CHEMBL61665 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077598&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10739299 103970367 CHEMBL61665 ZINC29571663 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135600 Oc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2 VBTFJGYCISLKEQ-UHFFFAOYSA-N 50069914 3-(2-Benzylamino-ethoxy)-phenol::CHEMBL64508 D(2) dopamine receptor Rattus norvegicus 115 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069914&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11776546 103963876 CHEMBL64508 ZINC12355952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135604 Clc1c[nH]c2c(Cl)ccc(OCCNCc3ccccc3)c12 InChI=1S/C17H16Cl2N2O/c18-13-6-7-15(16-14(19)11-21-17(13)16)22-9-8-20-10-12-4-2-1-3-5-12/h1-7,11,20-21H,8-10H2 MOXUIBWAFLAGIL-UHFFFAOYSA-N 50077575 Benzyl-[2-(3,7-dichloro-1H-indol-4-yloxy)-ethyl]-amine::CHEMBL294204 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9862532 103970344 CHEMBL294204 ZINC01903130 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135607 Clc1ccc(OCCNCc2ccsc2)c2CC(=O)Nc12 InChI=1S/C15H15ClN2O2S/c16-12-1-2-13(11-7-14(19)18-15(11)12)20-5-4-17-8-10-3-6-21-9-10/h1-3,6,9,17H,4-5,7-8H2,(H,18,19) YJANKLWIHLPIFX-UHFFFAOYSA-N 50077580 7-Chloro-4-{2-[(thiophen-3-ylmethyl)-amino]-ethoxy}-1,3-dihydro-indol-2-one::CHEMBL64466 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077580&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840168 103970349 CHEMBL64466 ZINC26165738 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135613 Clc1c[nH]c2c(Cl)ccc(OCCNCc3cccs3)c12 InChI=1S/C15H14Cl2N2OS/c16-11-3-4-13(14-12(17)9-19-15(11)14)20-6-5-18-8-10-2-1-7-21-10/h1-4,7,9,18-19H,5-6,8H2 KAHGPKAAVFDLKE-UHFFFAOYSA-N 50077579 CHEMBL64509::[2-(3,7-Dichloro-1H-indol-4-yloxy)-ethyl]-thiophen-2-ylmethyl-amine D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077579&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10783399 103970348 CHEMBL64509 ZINC01903135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135614 Fc1ccc(OCCNCc2cccc(c2)-c2ccccc2)c2CC(=O)Nc12 InChI=1S/C23H21FN2O2/c24-20-9-10-21(19-14-22(27)26-23(19)20)28-12-11-25-15-16-5-4-8-18(13-16)17-6-2-1-3-7-17/h1-10,13,25H,11-12,14-15H2,(H,26,27) SUNPULXJCJNRPQ-UHFFFAOYSA-N 50077603 4-{2-[(Biphenyl-3-ylmethyl)-amino]-ethoxy}-7-fluoro-1,3-dihydro-indol-2-one::CHEMBL418681 D(2) dopamine receptor Rattus norvegicus 0.930000 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077603&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10643240 103970372 CHEMBL418681 ZINC26163524 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135617 C(COc1cccc2[nH]ccc12)NCc1ccccc1 InChI=1S/C17H18N2O/c1-2-5-14(6-3-1)13-18-11-12-20-17-8-4-7-16-15(17)9-10-19-16/h1-10,18-19H,11-13H2 ZEHDEZWEFBOGNZ-UHFFFAOYSA-N 50077576 Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine::CHEMBL64283 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9838216 103970345 CHEMBL64283 ZINC01903142 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50135619 CN(CCOc1ccc(Cl)c2NC(=O)Cc12)Cc1ccccc1 InChI=1S/C18H19ClN2O2/c1-21(12-13-5-3-2-4-6-13)9-10-23-16-8-7-15(19)18-14(16)11-17(22)20-18/h2-8H,9-12H2,1H3,(H,20,22) KNYXWJRBLXUOLM-UHFFFAOYSA-N 50077593 4-[2-(Benzyl-methyl-amino)-ethoxy]-7-chloro-1,3-dihydro-indol-2-one::CHEMBL59501 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm990023s 10.7270/Q25D8R1W 10354409 Mewshaw, RE; Webb, MB; Marquis, KL; McGaughey, GB; Shi, X; Wasik, T; Scerni, R; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077593&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10544453 103970362 CHEMBL59501 ZINC29570549 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139985 Clc1ccccc1N1CCC(CNCC2COc3ccccc3O2)CC1 InChI=1S/C21H25ClN2O2/c22-18-5-1-2-6-19(18)24-11-9-16(10-12-24)13-23-14-17-15-25-20-7-3-4-8-21(20)26-17/h1-8,16-17,23H,9-15H2 CSWPZFOPVQMWKT-UHFFFAOYSA-N 50079952 CHEMBL112526::[1-(2-Chloro-phenyl)-piperidin-4-ylmethyl]-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-amine D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10714368 103972066 CHEMBL112526 ZINC13799892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139986 C(NCC1COc2ccccc2O1)C1CCN(CC1)c1ccccc1 InChI=1S/C21H26N2O2/c1-2-6-18(7-3-1)23-12-10-17(11-13-23)14-22-15-19-16-24-20-8-4-5-9-21(20)25-19/h1-9,17,19,22H,10-16H2 DXFCGSGBNDZTRJ-UHFFFAOYSA-N 50079943 (2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-phenyl-piperidin-4-ylmethyl)-amine::CHEMBL112033 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079943&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10664759 103972057 CHEMBL112033 ZINC13799886 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139989 COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1 InChI=1S/C22H27ClN2O3/c1-26-20-5-3-2-4-19(20)25-10-8-16(9-11-25)13-24-14-18-15-27-21-7-6-17(23)12-22(21)28-18/h2-7,12,16,18,24H,8-11,13-15H2,1H3 QHLRKDSRGUZHSH-UHFFFAOYSA-N 50079939 (7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2-methoxy-phenyl)-piperidin-4-ylmethyl]-amine::CHEMBL418854 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9865858 103972053 CHEMBL418854 ZINC03828998 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139991 C(Nc1ncccn1)C1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C19H24N4O2/c1-2-5-18-17(4-1)24-14-16(25-18)13-23-10-6-15(7-11-23)12-22-19-20-8-3-9-21-19/h1-5,8-9,15-16H,6-7,10-14H2,(H,20,21,22) OLBKIOIWVFSFFV-UHFFFAOYSA-N 50079940 CHEMBL324076::[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-ylmethyl]-pyrimidin-2-yl-amine D(2) dopamine receptor Rattus norvegicus 6.90 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079940&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44341301 103972054 CHEMBL324076 ZINC13799875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139992 COc1cccc(c1)N1CCC(CNCC2COc3ccccc3O2)CC1 InChI=1S/C22H28N2O3/c1-25-19-6-4-5-18(13-19)24-11-9-17(10-12-24)14-23-15-20-16-26-21-7-2-3-8-22(21)27-20/h2-8,13,17,20,23H,9-12,14-16H2,1H3 DUTPDVWPQWRHMS-UHFFFAOYSA-N 50079947 (2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(3-methoxy-phenyl)-piperidin-4-ylmethyl]-amine::CHEMBL114331 D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10832838 103972061 CHEMBL114331 ZINC13799902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139994 COc1cccc2OC(CNCC3CCN(CC3)c3ncccn3)COc12 InChI=1S/C20H26N4O3/c1-25-17-4-2-5-18-19(17)26-14-16(27-18)13-21-12-15-6-10-24(11-7-15)20-22-8-3-9-23-20/h2-5,8-9,15-16,21H,6-7,10-14H2,1H3 ZWBHAGQLIGOXOP-UHFFFAOYSA-N 50079954 (5-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-pyrimidin-2-yl-piperidin-4-ylmethyl)-amine::CHEMBL115990 D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10666853 103972068 CHEMBL115990 ZINC13799853 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50140000 C(Nc1ncccn1)C1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C19H24N4O2/c1-2-5-18-17(4-1)24-14-16(25-18)13-23-10-6-15(7-11-23)12-22-19-20-8-3-9-21-19/h1-5,8-9,15-16H,6-7,10-14H2,(H,20,21,22) OLBKIOIWVFSFFV-UHFFFAOYSA-N 50079940 CHEMBL324076::[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-ylmethyl]-pyrimidin-2-yl-amine D(2) dopamine receptor Rattus norvegicus 6.9 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079940&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44341301 103972054 CHEMBL324076 ZINC13799875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50140002 COc1cccc2OCC(CNCC3CCN(CC3)c3ncccn3)Oc12 InChI=1S/C20H26N4O3/c1-25-17-4-2-5-18-19(17)27-16(14-26-18)13-21-12-15-6-10-24(11-7-15)20-22-8-3-9-23-20/h2-5,8-9,15-16,21H,6-7,10-14H2,1H3 ZVPBDPXZHYXGRS-UHFFFAOYSA-N 50079941 (8-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-pyrimidin-2-yl-piperidin-4-ylmethyl)-amine::CHEMBL112345 D(2) dopamine receptor Rattus norvegicus 76 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10737897 103972055 CHEMBL112345 ZINC13799848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50140006 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 5.1 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50140010 COc1ccccc1N1CCC(CNCC2COc3cccc(O)c3O2)CC1 InChI=1S/C22H28N2O4/c1-26-20-7-3-2-5-18(20)24-11-9-16(10-12-24)13-23-14-17-15-27-21-8-4-6-19(25)22(21)28-17/h2-8,16-17,23,25H,9-15H2,1H3 CHBUDRVHEPFQKH-UHFFFAOYSA-N 50079953 3-({[1-(2-Methoxy-phenyl)-piperidin-4-ylmethyl]-amino}-methyl)-2,3-dihydro-benzo[1,4]dioxin-5-ol::CHEMBL115931 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079953&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10572092 103972067 CHEMBL115931 ZINC13799857 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142148 Clc1cc(OCCNCc2ccccc2)c2[nH]c(=O)[nH]c2c1 InChI=1S/C16H16ClN3O2/c17-12-8-13-15(20-16(21)19-13)14(9-12)22-7-6-18-10-11-4-2-1-3-5-11/h1-5,8-9,18H,6-7,10H2,(H2,19,20,21) YKNNRQLCQGQFRB-UHFFFAOYSA-N 50081106 4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazol-2-one::CHEMBL329398 D(2) dopamine receptor Rattus norvegicus 2.7 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081106&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9861786 103981160 CHEMBL329398 ZINC02008275 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142155 C(COc1cccc2[nH]ccc12)NCc1ccccc1 InChI=1S/C17H18N2O/c1-2-5-14(6-3-1)13-18-11-12-20-17-8-4-7-16-15(17)9-10-19-16/h1-10,18-19H,11-13H2 ZEHDEZWEFBOGNZ-UHFFFAOYSA-N 50077576 Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine::CHEMBL64283 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9838216 103970345 CHEMBL64283 ZINC01903142 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142158 O=C1Cc2c(N1)cccc2OCCNCc1ccccc1 InChI=1S/C17H18N2O2/c20-17-11-14-15(19-17)7-4-8-16(14)21-10-9-18-12-13-5-2-1-3-6-13/h1-8,18H,9-12H2,(H,19,20) CVWQKEFTSSJDLS-UHFFFAOYSA-N 50077578 4-(2-Benzylamino-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL59752 D(2) dopamine receptor Rattus norvegicus 0.210000 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903877 103970347 CHEMBL59752 ZINC01903144 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142161 Cc1nc2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C17H19N3O/c1-13-19-15-8-5-9-16(17(15)20-13)21-11-10-18-12-14-6-3-2-4-7-14/h2-9,18H,10-12H2,1H3,(H,19,20) GGIUXVIFNJVWLE-UHFFFAOYSA-N 50081104 Benzyl-[2-(2-methyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine::CHEMBL87067 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081104&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9925730 103981158 CHEMBL87067 ZINC26576445 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142164 C(COc1cccc2nc[nH]c12)NCc1ccccc1 InChI=1S/C16H17N3O/c1-2-5-13(6-3-1)11-17-9-10-20-15-8-4-7-14-16(15)19-12-18-14/h1-8,12,17H,9-11H2,(H,18,19) XQWCSGWUJUEAQM-UHFFFAOYSA-N 50081111 CHEMBL89420::[2-(1H-Benzoimidazol-4-yloxy)-ethyl]-benzyl-amine D(2) dopamine receptor Rattus norvegicus 128 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081111&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9881815 103981165 CHEMBL89420 ZINC26577725 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142172 FC(F)(F)c1nc2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C17H16F3N3O/c18-17(19,20)16-22-13-7-4-8-14(15(13)23-16)24-10-9-21-11-12-5-2-1-3-6-12/h1-8,21H,9-11H2,(H,22,23) BKHJHBMOHZNYEP-UHFFFAOYSA-N 50081110 Benzyl-[2-(2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine::CHEMBL87192 D(2) dopamine receptor Rattus norvegicus 1.9 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081110&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840672 103981164 CHEMBL87192 ZINC03923630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142174 O=c1[nH]c2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C16H17N3O2/c20-16-18-13-7-4-8-14(15(13)19-16)21-10-9-17-11-12-5-2-1-3-6-12/h1-8,17H,9-11H2,(H2,18,19,20) MUGIIZXLOBYZRQ-UHFFFAOYSA-N 50081112 4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazol-2-one::CHEMBL314174 D(2) dopamine receptor Rattus norvegicus 4.7 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081112&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817253 103981166 CHEMBL314174 ZINC02008258 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142177 C(COc1cccc2[nH]ncc12)NCc1ccccc1 InChI=1S/C16H17N3O/c1-2-5-13(6-3-1)11-17-9-10-20-16-8-4-7-15-14(16)12-18-19-15/h1-8,12,17H,9-11H2,(H,18,19) WYGBVOBBNUHWLX-UHFFFAOYSA-N 50081109 Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine::CHEMBL87137 D(2) dopamine receptor Rattus norvegicus 36 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081109&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816808 103981163 CHEMBL87137 ZINC03917152 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142203 Oc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2 VBTFJGYCISLKEQ-UHFFFAOYSA-N 50069914 3-(2-Benzylamino-ethoxy)-phenol::CHEMBL64508 D(2) dopamine receptor Rattus norvegicus 101 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069914&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11776546 103963876 CHEMBL64508 ZINC12355952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139920 C(NCC1COc2ccccc2O1)C1CCN(CC1)c1ccccn1 InChI=1S/C20H25N3O2/c1-2-6-19-18(5-1)24-15-17(25-19)14-21-13-16-8-11-23(12-9-16)20-7-3-4-10-22-20/h1-7,10,16-17,21H,8-9,11-15H2 LTWGNOKBPCXOOT-UHFFFAOYSA-N 50079938 (2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-ylmethyl)-amine::CHEMBL112697 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079938&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19079020 103972052 CHEMBL112697 ZINC26993690 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139926 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 15.7 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139930 CN(CC1CCN(CC1)c1ncccn1)CC1COc2ccccc2O1 InChI=1S/C20H26N4O2/c1-23(14-17-15-25-18-5-2-3-6-19(18)26-17)13-16-7-11-24(12-8-16)20-21-9-4-10-22-20/h2-6,9-10,16-17H,7-8,11-15H2,1H3 LNKICWOWSGWZEK-UHFFFAOYSA-N 50079942 (2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-methyl-(1-pyrimidin-2-yl-piperidin-4-ylmethyl)-amine::CHEMBL114836 D(2) dopamine receptor Rattus norvegicus 260 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11792453 103972056 CHEMBL114836 ZINC27079728 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139931 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 359 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139936 C(NCC1COc2ccccc2O1)C1CCN(CC1)c1cccc2OCCOc12 InChI=1S/C23H28N2O4/c1-2-6-21-20(5-1)28-16-18(29-21)15-24-14-17-8-10-25(11-9-17)19-4-3-7-22-23(19)27-13-12-26-22/h1-7,17-18,24H,8-16H2 OGFDOBGWVXITBG-UHFFFAOYSA-N 50079946 (2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperidin-4-ylmethyl]-amine::CHEMBL115599 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10548781 103972060 CHEMBL115599 ZINC13799912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139941 CC1Oc2ccccc2OC1CNCC1CCN(CC1)c1ncccn1 InChI=1S/C20H26N4O2/c1-15-19(26-18-6-3-2-5-17(18)25-15)14-21-13-16-7-11-24(12-8-16)20-22-9-4-10-23-20/h2-6,9-10,15-16,19,21H,7-8,11-14H2,1H3 OGJLWAUKNAZCQP-UHFFFAOYSA-N 50079948 (3-Methyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-pyrimidin-2-yl-piperidin-4-ylmethyl)-amine::CHEMBL419397 D(2) dopamine receptor Rattus norvegicus 113 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10784327 103972062 CHEMBL419397 ZINC13799871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139952 C(CNc1ncccn1)NCC1COc2ccccc2O1 InChI=1S/C15H18N4O2/c1-2-5-14-13(4-1)20-11-12(21-14)10-16-8-9-19-15-17-6-3-7-18-15/h1-7,12,16H,8-11H2,(H,17,18,19) OHNWVGRHHDSMOD-UHFFFAOYSA-N 50079950 CHEMBL430698::N-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-N'-pyrimidin-2-yl-ethane-1,2-diamine D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10731942 103972064 CHEMBL430698 ZINC26995200 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139955 CC1(CNCC2CCN(CC2)c2ncccn2)COc2ccccc2O1 InChI=1S/C20H26N4O2/c1-20(15-25-17-5-2-3-6-18(17)26-20)14-21-13-16-7-11-24(12-8-16)19-22-9-4-10-23-19/h2-6,9-10,16,21H,7-8,11-15H2,1H3 LDDHERVSSWYDKG-UHFFFAOYSA-N 50079949 (2-Methyl-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-(1-pyrimidin-2-yl-piperidin-4-ylmethyl)-amine::CHEMBL324985 D(2) dopamine receptor Rattus norvegicus 97 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079949&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10736855 103972063 CHEMBL324985 ZINC13799862 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139959 COc1ccccc1N1CCC(CNCC2COc3cccc(F)c3O2)CC1 InChI=1S/C22H27FN2O3/c1-26-20-7-3-2-6-19(20)25-11-9-16(10-12-25)13-24-14-17-15-27-21-8-4-5-18(23)22(21)28-17/h2-8,16-17,24H,9-15H2,1H3 MVTOIWYCUADBKD-UHFFFAOYSA-N 50079951 (8-Fluoro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2-methoxy-phenyl)-piperidin-4-ylmethyl]-amine::CHEMBL322560 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079951&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19079030 103972065 CHEMBL322560 ZINC26996129 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139960 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139962 COc1ccccc1NCC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C22H28N2O3/c1-25-20-7-3-2-6-19(20)23-14-17-10-12-24(13-11-17)15-18-16-26-21-8-4-5-9-22(21)27-18/h2-9,17-18,23H,10-16H2,1H3 TYCFPCOJYDWOEP-UHFFFAOYSA-N 50079944 CHEMBL114852::[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-ylmethyl]-(2-methoxy-phenyl)-amine D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079944&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10785266 103972058 CHEMBL114852 ZINC13799918 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139965 C(NCC1COc2ccccc2O1)C1CCN(CC1)c1cccc2CCOc12 InChI=1S/C23H28N2O3/c1-2-7-22-21(6-1)27-16-19(28-22)15-24-14-17-8-11-25(12-9-17)20-5-3-4-18-10-13-26-23(18)20/h1-7,17,19,24H,8-16H2 CKEHNJZQODAPNT-UHFFFAOYSA-N 50079945 (2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2,3-dihydro-benzofuran-7-yl)-piperidin-4-ylmethyl]-amine::CHEMBL324403 D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10691211 103972059 CHEMBL324403 ZINC13799907 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139968 COc1ccc(cc1)N1CCC(CNCC2COc3ccccc3O2)CC1 InChI=1S/C22H28N2O3/c1-25-19-8-6-18(7-9-19)24-12-10-17(11-13-24)14-23-15-20-16-26-21-4-2-3-5-22(21)27-20/h2-9,17,20,23H,10-16H2,1H3 CAUVIHGEFYOEKK-UHFFFAOYSA-N 50079955 (2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(4-methoxy-phenyl)-piperidin-4-ylmethyl]-amine::CHEMBL111810 D(2) dopamine receptor Rattus norvegicus 36 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10690393 103972069 CHEMBL111810 ZINC13799899 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50139981 C(NCC1COc2ccccc2O1)C1CCN(CC1)c1ccccn1 InChI=1S/C20H25N3O2/c1-2-6-19-18(5-1)24-15-17(25-19)14-21-13-16-8-11-23(12-9-16)20-7-3-4-10-22-20/h1-7,10,16-17,21H,8-9,11-15H2 LTWGNOKBPCXOOT-UHFFFAOYSA-N 50079938 (2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-(3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-ylmethyl)-amine::CHEMBL112697 D(2) dopamine receptor Rattus norvegicus 27.0 ChEMBL 10.1021/jm9910122 10.7270/Q2WH2P6K 10464021 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL Knoll Pharmaceuticals http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50079938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50079938&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19079020 103972052 CHEMBL112697 ZINC26993690 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50156208 COc1cc-2c(C[C@@H]3N(C)CCc4cc(O)c(OC)c-2c34)cc1O InChI=1S/C19H21NO4/c1-20-5-4-10-7-15(22)19(24-3)18-12-9-16(23-2)14(21)8-11(12)6-13(20)17(10)18/h7-9,13,21-22H,4-6H2,1-3H3/t13-/m0/s1 LZJRNLRASBVRRX-ZDUSSCGKSA-N 50202318 (+)-boldine::(S)-(+)-Boldine::(S)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol::CHEMBL388342::boldine::cid_10154::cid_248507 D(2) dopamine receptor Rattus norvegicus 520 ChEMBL 10.1021/np990433j 10.7270/Q2Z037W0 10785418 Sobarzo-Sanchez, EM; Arbaoui, J; Protais, P; Cassels, BK Universidad de Chile http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202318&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10154 104081895 CHEMBL388342 C09365 ZINC00135449 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50156213 COc1cc-2c(C[C@@H]3N(C)CCc4c(I)c(O)c(OC)c-2c34)cc1O InChI=1S/C19H20INO4/c1-21-5-4-10-15-12(21)6-9-7-13(22)14(24-2)8-11(9)16(15)19(25-3)18(23)17(10)20/h7-8,12,22-23H,4-6H2,1-3H3/t12-/m0/s1 YCBIBKGMUXWRRT-LBPRGKRZSA-N 50202337 (S)-3-iodo-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol::3-Iodoboldine::CHEMBL256075 D(2) dopamine receptor Rattus norvegicus 96 ChEMBL 10.1021/np990433j 10.7270/Q2Z037W0 10785418 Sobarzo-Sanchez, EM; Arbaoui, J; Protais, P; Cassels, BK Universidad de Chile http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10004036 104081914 CHEMBL256075 ZINC29041634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50156214 COc1cc-2c(C[C@@H]3N(C)CCc4c(Cl)c(O)c(OC)c-2c34)cc1O InChI=1S/C19H20ClNO4/c1-21-5-4-10-15-12(21)6-9-7-13(22)14(24-2)8-11(9)16(15)19(25-3)18(23)17(10)20/h7-8,12,22-23H,4-6H2,1-3H3/t12-/m0/s1 HRPJZDTZANKXQI-LBPRGKRZSA-N 50269193 3-Chloroboldine::CHEMBL524439 D(2) dopamine receptor Rattus norvegicus 720 ChEMBL 10.1021/np990433j 10.7270/Q2Z037W0 10785418 Sobarzo-Sanchez, EM; Arbaoui, J; Protais, P; Cassels, BK Universidad de Chile http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50269193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50269193&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406315 104115151 CHEMBL524439 ZINC38794232 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50156215 COc1cc-2c(C[C@@H]3N(C)CCc4c(Br)c(O)c(OC)c-2c34)c(Br)c1O InChI=1S/C19H19Br2NO4/c1-22-5-4-8-13-11(22)6-10-9(7-12(25-2)17(23)16(10)21)14(13)19(26-3)18(24)15(8)20/h7,11,23-24H,4-6H2,1-3H3/t11-/m0/s1 FTUCKVYWXINSAK-NSHDSACASA-N 50209211 3,8-dibromoboldine::CHEMBL388564 D(2) dopamine receptor Rattus norvegicus 1910 ChEMBL 10.1021/np990433j 10.7270/Q2Z037W0 10785418 Sobarzo-Sanchez, EM; Arbaoui, J; Protais, P; Cassels, BK Universidad de Chile http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50209211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50209211&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10480509 104086033 CHEMBL388564 ZINC28647495 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50156216 COc1cc-2c(C[C@@H]3N(C)CCc4c(Br)c(O)c(OC)c-2c34)cc1O InChI=1S/C19H20BrNO4/c1-21-5-4-10-15-12(21)6-9-7-13(22)14(24-2)8-11(9)16(15)19(25-3)18(23)17(10)20/h7-8,12,22-23H,4-6H2,1-3H3/t12-/m0/s1 ORZPHDSNVICTTE-LBPRGKRZSA-N 50202340 (S)-3-bromo-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol::3-bromoboldine::CHEMBL225853 D(2) dopamine receptor Rattus norvegicus 1050 ChEMBL 10.1021/np990433j 10.7270/Q2Z037W0 10785418 Sobarzo-Sanchez, EM; Arbaoui, J; Protais, P; Cassels, BK Universidad de Chile http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10409038 104081917 CHEMBL225853 ZINC28647492 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165386 S=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)Nc1ccccc1 InChI=1S/C23H29N3O2S/c29-23(25-19-6-2-1-3-7-19)24-13-10-18-11-14-26(15-12-18)16-20-17-27-21-8-4-5-9-22(21)28-20/h1-9,18,20H,10-17H2,(H2,24,25,29) YUZZRQPWYLSRIR-UHFFFAOYSA-N 50092419 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-phenyl-thiourea::CHEMBL122677 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092419&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740374 103990564 CHEMBL122677 ZINC13813679 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165390 O=C(NC(=S)NCCC1CCN(CC2COc3ccccc3O2)CC1)c1ccccc1 InChI=1S/C24H29N3O3S/c28-23(19-6-2-1-3-7-19)26-24(31)25-13-10-18-11-14-27(15-12-18)16-20-17-29-21-8-4-5-9-22(21)30-20/h1-9,18,20H,10-17H2,(H2,25,26,28,31) CDHBLUWCCWHWDE-UHFFFAOYSA-N 50092424 1-Benzoyl-3-{2-[1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-thiourea::CHEMBL332855 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092424&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10765530 103990569 CHEMBL332855 ZINC13813687 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165392 O=C1N(CCC2CCN(CC3COc4ccccc4O3)CC2)Cc2ccccc12 InChI=1S/C24H28N2O3/c27-24-21-6-2-1-5-19(21)15-26(24)14-11-18-9-12-25(13-10-18)16-20-17-28-22-7-3-4-8-23(22)29-20/h1-8,18,20H,9-17H2 AHGHHUGEWXNAIS-UHFFFAOYSA-N 50092425 2-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-2,3-dihydro-isoindol-1-one::CHEMBL121638 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092425&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10548552 103990570 CHEMBL121638 ZINC12356324 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165395 O=C(NCC1CCN(CC2COc3ccccc3O2)CC1)Nc1ccccc1 InChI=1S/C22H27N3O3/c26-22(24-18-6-2-1-3-7-18)23-14-17-10-12-25(13-11-17)15-19-16-27-20-8-4-5-9-21(20)28-19/h1-9,17,19H,10-16H2,(H2,23,24,26) ZMBZINVTWBFKMC-UHFFFAOYSA-N 50092418 1-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-ylmethyl]-3-phenyl-urea::CHEMBL123666 D(2) dopamine receptor Rattus norvegicus 750 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10619846 103990563 CHEMBL123666 ZINC27198114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165397 COc1ccc(NC(=O)NCCC2CCN(CC3COc4ccccc4O3)CC2)cc1 InChI=1S/C24H31N3O4/c1-29-20-8-6-19(7-9-20)26-24(28)25-13-10-18-11-14-27(15-12-18)16-21-17-30-22-4-2-3-5-23(22)31-21/h2-9,18,21H,10-17H2,1H3,(H2,25,26,28) ROHZYDZHQKABEJ-UHFFFAOYSA-N 50092427 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-(4-methoxy-phenyl)-urea::CHEMBL121640 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10741057 103990572 CHEMBL121640 ZINC13813642 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165383 CC(C)c1cccc(C(C)C)c1N1CCN(CCC2CCN(CC3COc4ccccc4O3)CC2)C1=O InChI=1S/C31H43N3O3/c1-22(2)26-8-7-9-27(23(3)4)30(26)34-19-18-33(31(34)35)17-14-24-12-15-32(16-13-24)20-25-21-36-28-10-5-6-11-29(28)37-25/h5-11,22-25H,12-21H2,1-4H3 PBTGVANSAJOWQK-UHFFFAOYSA-N 50092417 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-(2,6-diisopropyl-phenyl)-imidazolidin-2-one::CHEMBL124288 D(2) dopamine receptor Rattus norvegicus 480 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092417&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10505736 103990562 CHEMBL124288 ZINC13813726 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165405 O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)Oc1ccccc1 InChI=1S/C23H28N2O4/c26-23(29-19-6-2-1-3-7-19)24-13-10-18-11-14-25(15-12-18)16-20-17-27-21-8-4-5-9-22(21)28-20/h1-9,18,20H,10-17H2,(H,24,26) XJRQIMUDQRZPFW-UHFFFAOYSA-N 50092432 CHEMBL332790::{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-carbamic acid phenyl ester D(2) dopamine receptor Rattus norvegicus 52 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092432&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10572842 103990577 CHEMBL332790 ZINC12356319 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165409 CN(CCC1CCN(CC2COc3ccccc3O2)CC1)C(=O)N(C)c1ccccc1 InChI=1S/C25H33N3O3/c1-26(25(29)27(2)21-8-4-3-5-9-21)15-12-20-13-16-28(17-14-20)18-22-19-30-23-10-6-7-11-24(23)31-22/h3-11,20,22H,12-19H2,1-2H3 DDJLQAHUKUEJJT-UHFFFAOYSA-N 50092437 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-1,3-dimethyl-3-phenyl-urea::CHEMBL121140 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092437&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740970 103990582 CHEMBL121140 ZINC13813701 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165410 O=C1Nc2ccccc2CCN1CCC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C25H31N3O3/c29-25-26-22-6-2-1-5-20(22)12-16-28(25)15-11-19-9-13-27(14-10-19)17-21-18-30-23-7-3-4-8-24(23)31-21/h1-8,19,21H,9-18H2,(H,26,29) AVPPBLUOVDZTAO-UHFFFAOYSA-N 50092439 3-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-1,3,4,5-tetrahydro-benzo[d][1,3]diazepin-2-one::CHEMBL120836 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10622094 103990584 CHEMBL120836 ZINC12356415 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165411 O=C1Nc2ccccc2CN1CC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C23H27N3O3/c27-23-24-20-6-2-1-5-18(20)14-26(23)13-17-9-11-25(12-10-17)15-19-16-28-21-7-3-4-8-22(21)29-19/h1-8,17,19H,9-16H2,(H,24,27) KGMWQXLGOCKKNE-UHFFFAOYSA-N 50092436 3-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-ylmethyl]-3,4-dihydro-1H-quinazolin-2-one::CHEMBL121315 D(2) dopamine receptor Rattus norvegicus 550 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10524624 103990581 CHEMBL121315 ZINC27190420 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165412 COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 BLGXFZZNTVWLAY-SCYLSFHTSA-N 50013515 (+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester D(2) dopamine receptor Rattus norvegicus 1125 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8969 103925641 48565 CHEMBL15245 DB01392 102 C09256 ZINC03860825 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165415 Cc1ccc(cc1)S(=O)(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C23H30N2O4S/c1-18-6-8-21(9-7-18)30(26,27)24-13-10-19-11-14-25(15-12-19)16-20-17-28-22-4-2-3-5-23(22)29-20/h2-9,19-20,24H,10-17H2,1H3 KZCXDHLCHUSVLI-UHFFFAOYSA-N 50092438 CHEMBL123434::N-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-4-methyl-benzenesulfonamide D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717529 103990583 CHEMBL123434 ZINC13813632 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165418 O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)NC(=O)c1ccccc1 InChI=1S/C24H29N3O4/c28-23(19-6-2-1-3-7-19)26-24(29)25-13-10-18-11-14-27(15-12-18)16-20-17-30-21-8-4-5-9-22(21)31-20/h1-9,18,20H,10-17H2,(H2,25,26,28,29) JHLLCDAGMAZZJO-UHFFFAOYSA-N 50092440 1-Benzoyl-3-{2-[1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-urea::CHEMBL122735 D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10764754 103990585 CHEMBL122735 ZINC13813671 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165419 C(Nc1nc2ccccc2s1)C1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C22H25N3O2S/c1-4-8-21-18(5-1)24-22(28-21)23-13-16-9-11-25(12-10-16)14-17-15-26-19-6-2-3-7-20(19)27-17/h1-8,16-17H,9-15H2,(H,23,24) WKDICWUJRAUKFM-UHFFFAOYSA-N 50092442 Benzothiazol-2-yl-[1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-ylmethyl]-amine(R 47243)::CHEMBL120819 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128556 103990587 CHEMBL120819 ZINC06118722 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165422 O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)C(c1ccccc1)c1ccccc1 InChI=1S/C30H34N2O3/c33-30(29(24-9-3-1-4-10-24)25-11-5-2-6-12-25)31-18-15-23-16-19-32(20-17-23)21-26-22-34-27-13-7-8-14-28(27)35-26/h1-14,23,26,29H,15-22H2,(H,31,33) SAMSZIWMYYPCOJ-UHFFFAOYSA-N 50092426 CHEMBL421262::N-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-2,2-diphenyl-acetamide D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092426&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10719172 103990571 CHEMBL421262 ZINC13813622 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165385 Clc1cccc(Cl)c1N1CCN(CCC2CCN(CC3COc4ccccc4O3)CC2)C1=O InChI=1S/C25H29Cl2N3O3/c26-20-4-3-5-21(27)24(20)30-15-14-29(25(30)31)13-10-18-8-11-28(12-9-18)16-19-17-32-22-6-1-2-7-23(22)33-19/h1-7,18-19H,8-17H2 ZJFDCQNJERMIKE-UHFFFAOYSA-N 50092421 1-(2,6-Dichloro-phenyl)-3-{2-[1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-imidazolidin-2-one::CHEMBL121497 D(2) dopamine receptor Rattus norvegicus 2.3 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10601126 103990566 CHEMBL121497 ZINC13813720 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165424 [O-][N+](=O)c1ccccc1C(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C23H27N3O5/c27-23(19-5-1-2-6-20(19)26(28)29)24-12-9-17-10-13-25(14-11-17)15-18-16-30-21-7-3-4-8-22(21)31-18/h1-8,17-18H,9-16H2,(H,24,27) XTQFNJSMJJDQSD-UHFFFAOYSA-N 50092445 CHEMBL121131::N-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-2-nitro-benzamide D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10646054 103990590 CHEMBL121131 ZINC13813586 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165427 Oc1ccc(NC(=O)NCCC2CCN(CC3COc4ccccc4O3)CC2)cc1 InChI=1S/C23H29N3O4/c27-19-7-5-18(6-8-19)25-23(28)24-12-9-17-10-13-26(14-11-17)15-20-16-29-21-3-1-2-4-22(21)30-20/h1-8,17,20,27H,9-16H2,(H2,24,25,28) YYCJXQMVIXDIPD-UHFFFAOYSA-N 50092446 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-(4-hydroxy-phenyl)-urea::CHEMBL122821 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10787782 103990591 CHEMBL122821 ZINC13813649 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165432 O=C1N(CCC2CCN(CC3COc4ccccc4O3)CC2)C(=O)c2ccccc12 InChI=1S/C24H26N2O4/c27-23-19-5-1-2-6-20(19)24(28)26(23)14-11-17-9-12-25(13-10-17)15-18-16-29-21-7-3-4-8-22(21)30-18/h1-8,17-18H,9-16H2 VODCXRCWROSAKX-UHFFFAOYSA-N 50092431 2-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-isoindole-1,3-dione::CHEMBL121219 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811319 103990576 CHEMBL121219 ZINC13813780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165433 O=C1N(CCC2CCN(CC3COc4ccccc4O3)CC2)CCCN1c1ccccc1 InChI=1S/C26H33N3O3/c30-26-28(14-6-15-29(26)22-7-2-1-3-8-22)18-13-21-11-16-27(17-12-21)19-23-20-31-24-9-4-5-10-25(24)32-23/h1-5,7-10,21,23H,6,11-20H2 FFXZAVMSBRRUNZ-UHFFFAOYSA-N 50092428 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-phenyl-tetrahydro-pyrimidin-2-one::CHEMBL123139 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092428&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10503029 103990573 CHEMBL123139 ZINC13813774 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165444 CS(=O)(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C17H26N2O4S/c1-24(20,21)18-9-6-14-7-10-19(11-8-14)12-15-13-22-16-4-2-3-5-17(16)23-15/h2-5,14-15,18H,6-13H2,1H3 GWVSKFQVFXIYMQ-UHFFFAOYSA-N 50092450 CHEMBL123383::N-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 800 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092450&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10546071 103990595 CHEMBL123383 ZINC12356112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165445 [O-][N+](=O)c1ccccc1CC(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C24H29N3O5/c28-24(15-19-5-1-2-6-21(19)27(29)30)25-12-9-18-10-13-26(14-11-18)16-20-17-31-22-7-3-4-8-23(22)32-20/h1-8,18,20H,9-17H2,(H,25,28) GPSUKPDJVAFHNV-UHFFFAOYSA-N 50092453 CHEMBL120989::N-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-2-(2-nitro-phenyl)-acetamide D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10741708 103990598 CHEMBL120989 ZINC13813612 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165446 C1CN=C(N1)C1COc2ccccc2O1 InChI=1S/C11H12N2O2/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11/h1-4,10H,5-7H2,(H,12,13) HPMRFMKYPGXPEP-UHFFFAOYSA-N 50019848 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole::4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1H-imidazole::CHEMBL10316::Idazoxan::US8633208, Idazoxan D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54459 103930771 5862 CHEMBL10316 C10968 ZINC00900630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165448 O=C1N(CCC2CCN(CC3COc4ccccc4O3)CC2)CCN1c1ccccc1 InChI=1S/C25H31N3O3/c29-25-27(16-17-28(25)21-6-2-1-3-7-21)15-12-20-10-13-26(14-11-20)18-22-19-30-23-8-4-5-9-24(23)31-22/h1-9,20,22H,10-19H2 QDSZCLOZPZIBJX-UHFFFAOYSA-N 50092452 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-phenyl-imidazolidin-2-one::CHEMBL122889 D(2) dopamine receptor Rattus norvegicus 4.5 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092452&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9888447 103990597 CHEMBL122889 ZINC12356426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165451 O=C(NCCCC1CCN(CC2COc3ccccc3O2)CC1)Nc1ccccc1 InChI=1S/C24H31N3O3/c28-24(26-20-8-2-1-3-9-20)25-14-6-7-19-12-15-27(16-13-19)17-21-18-29-22-10-4-5-11-23(22)30-21/h1-5,8-11,19,21H,6-7,12-18H2,(H2,25,26,28) ZLOMGHVTJDXSST-UHFFFAOYSA-N 50092422 1-{3-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-propyl}-3-phenyl-urea::CHEMBL123328 D(2) dopamine receptor Rattus norvegicus 90 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10525586 103990567 CHEMBL123328 ZINC27197640 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165457 COc1ccccc1C(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C24H30N2O4/c1-28-21-7-3-2-6-20(21)24(27)25-13-10-18-11-14-26(15-12-18)16-19-17-29-22-8-4-5-9-23(22)30-19/h2-9,18-19H,10-17H2,1H3,(H,25,27) LGZRWXMJVFXJEV-UHFFFAOYSA-N 50092456 CHEMBL120878::N-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10573626 103990601 CHEMBL120878 ZINC13813594 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165463 O=C1Nc2ccccc2CN1CCC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C24H29N3O3/c28-24-25-21-6-2-1-5-19(21)15-27(24)14-11-18-9-12-26(13-10-18)16-20-17-29-22-7-3-4-8-23(22)30-20/h1-8,18,20H,9-17H2,(H,25,28) GJYKVQRJNCOILI-UHFFFAOYSA-N 50092429 3-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3,4-dihydro-1H-quinazolin-2-one::CHEMBL120837 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092429&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692781 103990574 CHEMBL120837 ZINC12356381 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165464 [O-][N+](=O)c1ccc(NC(=O)NCCC2CCN(CC3COc4ccccc4O3)CC2)cc1 InChI=1S/C23H28N4O5/c28-23(25-18-5-7-19(8-6-18)27(29)30)24-12-9-17-10-13-26(14-11-17)15-20-16-31-21-3-1-2-4-22(21)32-20/h1-8,17,20H,9-16H2,(H2,24,25,28) QZJARKYJDRPUEY-UHFFFAOYSA-N 50092423 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-(4-nitro-phenyl)-urea::CHEMBL420891 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092423&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10527067 103990568 CHEMBL420891 C02125 ZINC13813656 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165465 Cc1cccc(C)c1N1CCN(CCC2CCN(CC3COc4ccccc4O3)CC2)C1=O InChI=1S/C27H35N3O3/c1-20-6-5-7-21(2)26(20)30-17-16-29(27(30)31)15-12-22-10-13-28(14-11-22)18-23-19-32-24-8-3-4-9-25(24)33-23/h3-9,22-23H,10-19H2,1-2H3 XEVPCWZBRVLBPV-UHFFFAOYSA-N 50092449 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-(2,6-dimethyl-phenyl)-imidazolidin-2-one::CHEMBL121590 D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092449&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10671227 103990594 CHEMBL121590 ZINC13813717 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165470 O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)c1ccccc1 InChI=1S/C23H28N2O3/c26-23(19-6-2-1-3-7-19)24-13-10-18-11-14-25(15-12-18)16-20-17-27-21-8-4-5-9-22(21)28-20/h1-9,18,20H,10-17H2,(H,24,26) JXRCQDARHHCZDE-UHFFFAOYSA-N 50092457 CHEMBL121698::N-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-benzamide D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10643509 103990602 CHEMBL121698 ZINC12356275 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165477 O=C(Nc1ccccc1)OCCC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C23H28N2O4/c26-23(24-19-6-2-1-3-7-19)27-15-12-18-10-13-25(14-11-18)16-20-17-28-21-8-4-5-9-22(21)29-20/h1-9,18,20H,10-17H2,(H,24,26) SKDDXYKWEBLIJW-UHFFFAOYSA-N 50092448 CHEMBL331327::Phenyl-carbamic acid 2-[1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl ester D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092448&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10572841 103990593 CHEMBL331327 ZINC13813709 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165480 CN(C(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1)c1ccccc1 InChI=1S/C24H31N3O3/c1-26(20-7-3-2-4-8-20)24(28)25-14-11-19-12-15-27(16-13-19)17-21-18-29-22-9-5-6-10-23(22)30-21/h2-10,19,21H,11-18H2,1H3,(H,25,28) ZWFOVLJNNFKCBE-UHFFFAOYSA-N 50092443 3-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-1-methyl-1-phenyl-urea::CHEMBL120812 D(2) dopamine receptor Rattus norvegicus 11.5 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669241 103990588 CHEMBL120812 ZINC13813666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165486 O=C1N(CCC2CCN(CC3COc4ccccc4O3)CC2)CCN1c1ccncc1 InChI=1S/C24H30N4O3/c29-24-27(15-16-28(24)20-5-10-25-11-6-20)14-9-19-7-12-26(13-8-19)17-21-18-30-22-3-1-2-4-23(22)31-21/h1-6,10-11,19,21H,7-9,12-18H2 FMFOZEFYIOCIHK-UHFFFAOYSA-N 50092455 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-pyridin-4-yl-imidazolidin-2-one::CHEMBL121675 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092455&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740921 103990600 CHEMBL121675 ZINC13813768 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165490 CN(CCC1CCN(CC2COc3ccccc3O2)CC1)C(=O)Nc1ccccc1 InChI=1S/C24H31N3O3/c1-26(24(28)25-20-7-3-2-4-8-20)14-11-19-12-15-27(16-13-19)17-21-18-29-22-9-5-6-10-23(22)30-21/h2-10,19,21H,11-18H2,1H3,(H,25,28) NCFQNALJMWRWNO-UHFFFAOYSA-N 50092430 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-1-methyl-3-phenyl-urea::CHEMBL121811 D(2) dopamine receptor Rattus norvegicus 36 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092430&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9844399 103990575 CHEMBL121811 ZINC13813695 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165491 S=C(NCC1CCN(CC2COc3ccccc3O2)CC1)Nc1ccccc1 InChI=1S/C22H27N3O2S/c28-22(24-18-6-2-1-3-7-18)23-14-17-10-12-25(13-11-17)15-19-16-26-20-8-4-5-9-21(20)27-19/h1-9,17,19H,10-16H2,(H2,23,24,28) RNSJPUZYZKKDCL-UHFFFAOYSA-N 50092441 1-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-ylmethyl]-3-phenyl-thiourea::CHEMBL332741 D(2) dopamine receptor Rattus norvegicus 750 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092441&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10763359 103990586 CHEMBL332741 ZINC27197625 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165496 COc1cccc(OC)c1N1CCN(CCC2CCN(CC3COc4ccccc4O3)CC2)C1=O InChI=1S/C27H35N3O5/c1-32-24-8-5-9-25(33-2)26(24)30-17-16-29(27(30)31)15-12-20-10-13-28(14-11-20)18-21-19-34-22-6-3-4-7-23(22)35-21/h3-9,20-21H,10-19H2,1-2H3 GDFJXSNFSJUFOA-UHFFFAOYSA-N 50092447 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-(2,6-dimethoxy-phenyl)-imidazolidin-2-one::CHEMBL123470 D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10528772 103990592 CHEMBL123470 ZINC13813733 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165498 COc1ccccc1CC(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C25H32N2O4/c1-29-22-7-3-2-6-20(22)16-25(28)26-13-10-19-11-14-27(15-12-19)17-21-18-30-23-8-4-5-9-24(23)31-21/h2-9,19,21H,10-18H2,1H3,(H,26,28) BJZNBVQDZCYPGI-UHFFFAOYSA-N 50092458 CHEMBL119767::N-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-2-(2-methoxy-phenyl)-acetamide D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10526357 103990603 CHEMBL119767 ZINC13813603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165501 O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)NCc1ccccc1 InChI=1S/C24H31N3O3/c28-24(26-16-20-6-2-1-3-7-20)25-13-10-19-11-14-27(15-12-19)17-21-18-29-22-8-4-5-9-23(22)30-21/h1-9,19,21H,10-18H2,(H2,25,26,28) AZTPXOVZDKZKIX-UHFFFAOYSA-N 50092420 1-Benzyl-3-{2-[1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-urea::CHEMBL331209 D(2) dopamine receptor Rattus norvegicus 45 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092420&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740272 103990565 CHEMBL331209 ZINC12356372 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165503 O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)Nc1ccccc1 InChI=1S/C23H29N3O3/c27-23(25-19-6-2-1-3-7-19)24-13-10-18-11-14-26(15-12-18)16-20-17-28-21-8-4-5-9-22(21)29-20/h1-9,18,20H,10-17H2,(H2,24,25,27) MXHFBGKZQZRDCZ-UHFFFAOYSA-N 50092434 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-phenyl-urea::CHEMBL421265 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10834528 103990579 CHEMBL421265 ZINC13813635 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165504 O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)NC1CCCCC1 InChI=1S/C23H35N3O3/c27-23(25-19-6-2-1-3-7-19)24-13-10-18-11-14-26(15-12-18)16-20-17-28-21-8-4-5-9-22(21)29-20/h4-5,8-9,18-20H,1-3,6-7,10-17H2,(H2,24,25,27) RHMDXGNHLMFANS-UHFFFAOYSA-N 50092451 1-Cyclohexyl-3-{2-[1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-urea::CHEMBL122215 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092451&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10644754 103990596 CHEMBL122215 ZINC13813662 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165511 COc1cc(OC)c(N2CCN(CCC3CCN(CC4COc5ccccc5O4)CC3)C2=O)c(OC)c1 InChI=1S/C28H37N3O6/c1-33-21-16-25(34-2)27(26(17-21)35-3)31-15-14-30(28(31)32)13-10-20-8-11-29(12-9-20)18-22-19-36-23-6-4-5-7-24(23)37-22/h4-7,16-17,20,22H,8-15,18-19H2,1-3H3 PBLAPYRVHBZQPW-UHFFFAOYSA-N 50092435 1-{2-[1-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-3-(2,4,6-trimethoxy-phenyl)-imidazolidin-2-one::CHEMBL121262 D(2) dopamine receptor Rattus norvegicus 320 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092435&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10369120 103990580 CHEMBL121262 ZINC13813750 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50165513 CCOc1cccc(OCC)c1N1CCN(CCC2CCN(CC3COc4ccccc4O3)CC2)C1=O InChI=1S/C29H39N3O5/c1-3-34-26-10-7-11-27(35-4-2)28(26)32-19-18-31(29(32)33)17-14-22-12-15-30(16-13-22)20-23-21-36-24-8-5-6-9-25(24)37-23/h5-11,22-23H,3-4,12-21H2,1-2H3 HEDSIQXYSQYELN-UHFFFAOYSA-N 50092454 1-(2,6-Diethoxy-phenyl)-3-{2-[1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidin-4-yl]-ethyl}-imidazolidin-2-one::CHEMBL431481 D(2) dopamine receptor Rattus norvegicus 135 ChEMBL 10.1021/jm991121g 10.7270/Q2MW2GD3 11020279 Mayer, P; Brunel, P; Chaplain, C; Piedecoq, C; Calmel, F; Schambel, P; Chopin, P; Wurch, T; Pauwels, PJ; Marien, M; Vidaluc, JL; Imbert, T Centre de Recherche Pierre Fabre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092454&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10815551 103990599 CHEMBL431481 ZINC13813741 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50163601 OC1(Cc2ccccc2)CCN(CC#Cc2ccc3[nH]c(=O)[nH]c3c2)CC1 InChI=1S/C22H23N3O2/c26-21-23-19-9-8-17(15-20(19)24-21)7-4-12-25-13-10-22(27,11-14-25)16-18-5-2-1-3-6-18/h1-3,5-6,8-9,15,27H,10-14,16H2,(H2,23,24,26) ALAHLCCSSRTDAZ-UHFFFAOYSA-N 50091626 5-[3-(4-Benzyl-4-hydroxy-piperidin-1-yl)-prop-1-ynyl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL326742 D(2) dopamine receptor Rattus norvegicus 86000 ChEMBL 10.1021/jm000023o 10.7270/Q2VH5N26 10978188 Wright, JL; Gregory, TF; Kesten, SR; Boxer, PA; Serpa, KA; Meltzer, LT; Wise, LD; Espitia, SA; Konkoy, CS; Whittemore, ER; Woodward, RM CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091626&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594749 103989867 CHEMBL326742 ZINC13813212 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50163603 COc1ccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)cc1 InChI=1S/C23H25N3O2/c1-28-20-7-4-18(5-8-20)15-19-10-13-26(14-11-19)12-2-3-17-6-9-21-22(16-17)25-23(27)24-21/h4-9,16,19H,10-15H2,1H3,(H2,24,25,27) DHGIUNURIAYCCZ-UHFFFAOYSA-N 50091628 5-{3-[4-(4-Methoxy-benzyl)-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL326568 D(2) dopamine receptor Rattus norvegicus 9900 ChEMBL 10.1021/jm000023o 10.7270/Q2VH5N26 10978188 Wright, JL; Gregory, TF; Kesten, SR; Boxer, PA; Serpa, KA; Meltzer, LT; Wise, LD; Espitia, SA; Konkoy, CS; Whittemore, ER; Woodward, RM CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091628&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809482 103989869 CHEMBL326568 ZINC13813206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50163616 Fc1ccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)cc1 InChI=1S/C22H22FN3O/c23-19-6-3-17(4-7-19)14-18-9-12-26(13-10-18)11-1-2-16-5-8-20-21(15-16)25-22(27)24-20/h3-8,15,18H,9-14H2,(H2,24,25,27) PNSPSQVGHSAHIY-UHFFFAOYSA-N 50091636 5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL19506 D(2) dopamine receptor Rattus norvegicus 1700 ChEMBL 10.1021/jm000023o 10.7270/Q2VH5N26 10978188 Wright, JL; Gregory, TF; Kesten, SR; Boxer, PA; Serpa, KA; Meltzer, LT; Wise, LD; Espitia, SA; Konkoy, CS; Whittemore, ER; Woodward, RM CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9998801 103989877 CHEMBL19506 ZINC01483725 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50161557 Oc1ccc(CC2NCCc3ccccc23)cc1O InChI=1S/C16H17NO2/c18-15-6-5-11(10-16(15)19)9-14-13-4-2-1-3-12(13)7-8-17-14/h1-6,10,14,17-19H,7-9H2 VWTDJIDABVMGQN-UHFFFAOYSA-N 50090489 4-(1,2,3,4-Tetrahydro-isoquinolin-1-ylmethyl)-benzene-1,2-diol::CHEMBL44877 D(2) dopamine receptor Rattus norvegicus 8790.0 ChEMBL 10.1016/s0960-894x(00)00326-7 10.7270/Q2M61JH0 10937721 Kawai, H; Kotake, Y; Ohta, S University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090489&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3044540 103988966 CHEMBL44877 ZINC20677058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50161559 C(C1NCCc2ccccc12)c1ccccc1 InChI=1S/C16H17N/c1-2-6-13(7-3-1)12-16-15-9-5-4-8-14(15)10-11-17-16/h1-9,16-17H,10-12H2 YRYCIFUZSUMAAY-UHFFFAOYSA-N 50017041 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline::1,2,3,4-Tetrahydro-1-(phenylmethyl)isoquinoline::1BnTIQ::CHEMBL21640::rac-(1R)-1-benzyl-1,2,3,4-tetrahydroisoquinoline D(2) dopamine receptor Rattus norvegicus 3570 ChEMBL 10.1016/s0960-894x(00)00326-7 10.7270/Q2M61JH0 10937721 Kawai, H; Kotake, Y; Ohta, S University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017041&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 98468 103928369 16804 CHEMBL21640 C05201 ZINC19624722 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50161560 Oc1cc2CCNC(Cc3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-9-12-6-7-17-14(13(12)10-16(15)19)8-11-4-2-1-3-5-11/h1-5,9-10,14,17-19H,6-8H2 GGGSEBXTKMTNBW-UHFFFAOYSA-N 50090488 1-Benzyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol::CHEMBL298285 D(2) dopamine receptor Rattus norvegicus 640 ChEMBL 10.1016/s0960-894x(00)00326-7 10.7270/Q2M61JH0 10937721 Kawai, H; Kotake, Y; Ohta, S University of Tokyo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 177511 103988965 CHEMBL298285 ZINC04724966 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50163617 Cc1ccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)cc1 InChI=1S/C23H25N3O/c1-17-4-6-19(7-5-17)15-20-10-13-26(14-11-20)12-2-3-18-8-9-21-22(16-18)25-23(27)24-21/h4-9,16,20H,10-15H2,1H3,(H2,24,25,27) LHUVDZHUMLCYFE-UHFFFAOYSA-N 50091632 5-{3-[4-(4-Methyl-benzyl)-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL419399 D(2) dopamine receptor Rattus norvegicus 14000 ChEMBL 10.1021/jm000023o 10.7270/Q2VH5N26 10978188 Wright, JL; Gregory, TF; Kesten, SR; Boxer, PA; Serpa, KA; Meltzer, LT; Wise, LD; Espitia, SA; Konkoy, CS; Whittemore, ER; Woodward, RM CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091632&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10689828 103989873 CHEMBL419399 ZINC13813203 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50163620 OC1(Cc2ccc(F)cc2)CCN(CC#Cc2ccc3[nH]c(=O)[nH]c3c2)CC1 InChI=1S/C22H22FN3O2/c23-18-6-3-17(4-7-18)15-22(28)9-12-26(13-10-22)11-1-2-16-5-8-19-20(14-16)25-21(27)24-19/h3-8,14,28H,9-13,15H2,(H2,24,25,27) UORACTXCIWIDCR-UHFFFAOYSA-N 50091629 5-{3-[4-(4-Fluoro-benzyl)-4-hydroxy-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL19576 D(2) dopamine receptor Rattus norvegicus 41000 ChEMBL 10.1021/jm000023o 10.7270/Q2VH5N26 10978188 Wright, JL; Gregory, TF; Kesten, SR; Boxer, PA; Serpa, KA; Meltzer, LT; Wise, LD; Espitia, SA; Konkoy, CS; Whittemore, ER; Woodward, RM CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091629&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10571768 103989870 CHEMBL19576 ZINC13813215 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50163654 O=c1[nH]c2ccc(cc2[nH]1)C#CCN1CCC(Cc2ccccc2)CC1 InChI=1S/C22H23N3O/c26-22-23-20-9-8-18(16-21(20)24-22)7-4-12-25-13-10-19(11-14-25)15-17-5-2-1-3-6-17/h1-3,5-6,8-9,16,19H,10-15H2,(H2,23,24,26) JJEXWPHPFZLTCU-UHFFFAOYSA-N 50091637 5-(3-(4-benzylpiperidin-1-yl)prop-1-ynyl)-1H-benzo[d]imidazol-2(3H)-one::5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL117260 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm000023o 10.7270/Q2VH5N26 10978188 Wright, JL; Gregory, TF; Kesten, SR; Boxer, PA; Serpa, KA; Meltzer, LT; Wise, LD; Espitia, SA; Konkoy, CS; Whittemore, ER; Woodward, RM CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9863010 103989878 CHEMBL117260 ZINC00023994 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50163675 Fc1cccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)c1 InChI=1S/C22H22FN3O/c23-19-5-1-3-18(14-19)13-17-8-11-26(12-9-17)10-2-4-16-6-7-20-21(15-16)25-22(27)24-20/h1,3,5-7,14-15,17H,8-13H2,(H2,24,25,27) MIIJMODVRMTWJP-UHFFFAOYSA-N 50091635 5-{3-[4-(3-Fluoro-benzyl)-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL19636 D(2) dopamine receptor Rattus norvegicus 3900 ChEMBL 10.1021/jm000023o 10.7270/Q2VH5N26 10978188 Wright, JL; Gregory, TF; Kesten, SR; Boxer, PA; Serpa, KA; Meltzer, LT; Wise, LD; Espitia, SA; Konkoy, CS; Whittemore, ER; Woodward, RM CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091635&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10808704 103989876 CHEMBL19636 ZINC13813209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50163686 Clc1ccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)cc1 InChI=1S/C22H22ClN3O/c23-19-6-3-17(4-7-19)14-18-9-12-26(13-10-18)11-1-2-16-5-8-20-21(15-16)25-22(27)24-20/h3-8,15,18H,9-14H2,(H2,24,25,27) QAHMMZQSMDIJJU-UHFFFAOYSA-N 50091643 5-{3-[4-(4-Chloro-benzyl)-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL325825 D(2) dopamine receptor Rattus norvegicus 3700 ChEMBL 10.1021/jm000023o 10.7270/Q2VH5N26 10978188 Wright, JL; Gregory, TF; Kesten, SR; Boxer, PA; Serpa, KA; Meltzer, LT; Wise, LD; Espitia, SA; Konkoy, CS; Whittemore, ER; Woodward, RM CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10547776 103989884 CHEMBL325825 ZINC13813201 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50176151 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1016/s0960-894x(01)00076-2 10.7270/Q2XD10XM 11294383 Thermos, K; Froudakis, GE; Tagmatarchis, N; Katerinopoulos, HE University of Crete http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50176154 NC1CCc2c(C1)ccc(O)c2O InChI=1S/C10H13NO2/c11-7-2-3-8-6(5-7)1-4-9(12)10(8)13/h1,4,7,12-13H,2-3,5,11H2 FSMRTTIHBZCVJG-UHFFFAOYSA-N 50028970 6-Amino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::CA inhibitor, 4::CHEMBL163912 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1016/s0960-894x(01)00076-2 10.7270/Q2XD10XM 11294383 Thermos, K; Froudakis, GE; Tagmatarchis, N; Katerinopoulos, HE University of Crete http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028970&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37631 103938105 CHEMBL163912 ZINC05784462 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179700 CCCN1CCc2cc(O)c(O)cc2[C@@H]1Cc1ccccc1 InChI=1S/C19H23NO2/c1-2-9-20-10-8-15-12-18(21)19(22)13-16(15)17(20)11-14-6-4-3-5-7-14/h3-7,12-13,17,21-22H,2,8-11H2,1H3/t17-/m0/s1 PEMATAWWKGESSC-KRWDZBQOSA-N 50099786 1-Benzyl-2-propyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol::CHEMBL49995 D(2) dopamine receptor Rattus norvegicus 14700 ChEMBL 10.1021/jm001128u 10.7270/Q2SB4517 11356113 Cabedo, N; Andreu, I; Ramirez De Arellano, MC; Chagraoui, A; Serrano, A; Bermejo, A; Protais, P; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10732779 103996611 CHEMBL49995 ZINC13862854 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179704 CCCN1CCc2cc3OCOc3cc2[C@@H]1Cc1ccccc1 InChI=1S/C20H23NO2/c1-2-9-21-10-8-16-12-19-20(23-14-22-19)13-17(16)18(21)11-15-6-4-3-5-7-15/h3-7,12-13,18H,2,8-11,14H2,1H3/t18-/m0/s1 SBYWPUOEYZOXNN-SFHVURJKSA-N 50099788 5-Benzyl-6-propyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline::CHEMBL53520 D(2) dopamine receptor Rattus norvegicus 21900 ChEMBL 10.1021/jm001128u 10.7270/Q2SB4517 11356113 Cabedo, N; Andreu, I; Ramirez De Arellano, MC; Chagraoui, A; Serrano, A; Bermejo, A; Protais, P; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099788&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10582557 103996613 CHEMBL53520 ZINC13862852 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179707 CCCN1CCc2cc3OCOc3cc2[C@H]1Cc1ccccc1 InChI=1S/C20H23NO2/c1-2-9-21-10-8-16-12-19-20(23-14-22-19)13-17(16)18(21)11-15-6-4-3-5-7-15/h3-7,12-13,18H,2,8-11,14H2,1H3/t18-/m1/s1 SBYWPUOEYZOXNN-GOSISDBHSA-N 50099790 5-Benzyl-6-propyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline::CHEMBL53483 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm001128u 10.7270/Q2SB4517 11356113 Cabedo, N; Andreu, I; Ramirez De Arellano, MC; Chagraoui, A; Serrano, A; Bermejo, A; Protais, P; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10852400 103996615 CHEMBL53483 ZINC13862853 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179708 CCCN1CCc2cc(O)c(O)cc2[C@H]1Cc1ccccc1 InChI=1S/C19H23NO2/c1-2-9-20-10-8-15-12-18(21)19(22)13-16(15)17(20)11-14-6-4-3-5-7-14/h3-7,12-13,17,21-22H,2,8-11H2,1H3/t17-/m1/s1 PEMATAWWKGESSC-QGZVFWFLSA-N 50099791 1-Benzyl-2-propyl-1,2,3,4-tetrahydro-isoquinoline-6,7-diol::CHEMBL54050 D(2) dopamine receptor Rattus norvegicus 61200.0 ChEMBL 10.1021/jm001128u 10.7270/Q2SB4517 11356113 Cabedo, N; Andreu, I; Ramirez De Arellano, MC; Chagraoui, A; Serrano, A; Bermejo, A; Protais, P; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10518133 103996616 CHEMBL54050 ZINC13862855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179710 C([C@@H]1NCCc2cc3OCOc3cc12)c1ccccc1 InChI=1S/C17H17NO2/c1-2-4-12(5-3-1)8-15-14-10-17-16(19-11-20-17)9-13(14)6-7-18-15/h1-5,9-10,15,18H,6-8,11H2/t15-/m0/s1 NURSVUHOJCWBJE-HNNXBMFYSA-N 50099789 5-Benzyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline::CHEMBL54051 D(2) dopamine receptor Rattus norvegicus 4000 ChEMBL 10.1021/jm001128u 10.7270/Q2SB4517 11356113 Cabedo, N; Andreu, I; Ramirez De Arellano, MC; Chagraoui, A; Serrano, A; Bermejo, A; Protais, P; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099789&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10400783 103996614 CHEMBL54051 ZINC11599230 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179712 C([C@H]1NCCc2cc3OCOc3cc12)c1ccccc1 InChI=1S/C17H17NO2/c1-2-4-12(5-3-1)8-15-14-10-17-16(19-11-20-17)9-13(14)6-7-18-15/h1-5,9-10,15,18H,6-8,11H2/t15-/m1/s1 NURSVUHOJCWBJE-OAHLLOKOSA-N 50099787 5-Benzyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline::CHEMBL301743 D(2) dopamine receptor Rattus norvegicus 53100.0 ChEMBL 10.1021/jm001128u 10.7270/Q2SB4517 11356113 Cabedo, N; Andreu, I; Ramirez De Arellano, MC; Chagraoui, A; Serrano, A; Bermejo, A; Protais, P; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099787&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10825736 103996612 CHEMBL301743 ZINC11599229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179720 COc1c(cc(Br)c2ccccc12)C(=O)NC1CCN(CC1)C1CCCCCC1 InChI=1S/C24H31BrN2O2/c1-29-23-20-11-7-6-10-19(20)22(25)16-21(23)24(28)26-17-12-14-27(15-13-17)18-8-4-2-3-5-9-18/h6-7,10-11,16-18H,2-5,8-9,12-15H2,1H3,(H,26,28) QUJXZUAZZBHKQA-UHFFFAOYSA-N 50099797 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cycloheptyl-piperidin-4-yl)-amide::CHEMBL53078 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599997 103996622 CHEMBL53078 ZINC13862859 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179725 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 7.6 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179727 COc1c(cc(Br)c2ccccc12)C(=O)NC1CC2CCCC(C1)N2C1CCCCCC1 InChI=1S/C27H35BrN2O2/c1-32-26-23-14-7-6-13-22(23)25(28)17-24(26)27(31)29-18-15-20-11-8-12-21(16-18)30(20)19-9-4-2-3-5-10-19/h6-7,13-14,17-21H,2-5,8-12,15-16H2,1H3,(H,29,31) WATKEYSVNBHFPF-UHFFFAOYSA-N 50099801 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (9-cycloheptyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide::CHEMBL298864 D(2) dopamine receptor Rattus norvegicus 152 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12084052 103996626 CHEMBL298864 ZINC13862886 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179729 COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CCN(C1)C1C2CCCC1CCC2 InChI=1S/C25H31BrN2O2/c1-30-24-20-11-3-2-10-19(20)22(26)14-21(24)25(29)27-18-12-13-28(15-18)23-16-6-4-7-17(23)9-5-8-16/h2-3,10-11,14,16-18,23H,4-9,12-13,15H2,1H3,(H,27,29)/t16?,17?,18-,23?/m0/s1 SWEOLYDPFYCLRX-RNBBLLSTSA-N 50099793 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-bicyclo[3.3.1]non-9-yl-pyrrolidin-3-yl)-amide::CHEMBL416846 D(2) dopamine receptor Rattus norvegicus 132 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099793&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10719188 103996618 CHEMBL416846 ZINC13862865 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179730 COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CCN(C1)C1CCCCC1 InChI=1S/C22H27BrN2O2/c1-27-21-18-10-6-5-9-17(18)20(23)13-19(21)22(26)24-15-11-12-25(14-15)16-7-3-2-4-8-16/h5-6,9-10,13,15-16H,2-4,7-8,11-12,14H2,1H3,(H,24,26)/t15-/m0/s1 UWMANVFYGMUYDW-HNNXBMFYSA-N 50099806 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclohexyl-pyrrolidin-3-yl)-amide::CHEMBL54865 D(2) dopamine receptor Rattus norvegicus 5.9 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10836428 103996631 CHEMBL54865 ZINC13862863 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179731 COc1cc(I)cc(C(=O)NC2CC3CCCC(C2)N3Cc2ccccc2)c1OC InChI=1S/C24H29IN2O3/c1-29-22-12-17(25)11-21(23(22)30-2)24(28)26-18-13-19-9-6-10-20(14-18)27(19)15-16-7-4-3-5-8-16/h3-5,7-8,11-12,18-20H,6,9-10,13-15H2,1-2H3,(H,26,28) RLMCMXONOFRGMR-UHFFFAOYSA-N 50099807 CHEMBL54866::N-(9-Benzyl-9-aza-bicyclo[3.3.1]non-3-yl)-5-iodo-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.05 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44297117 103996632 CHEMBL54866 ZINC13862888 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179735 COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CCN(C1)C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 InChI=1S/C26H31BrN2O2/c1-31-25-21-5-3-2-4-20(21)23(27)13-22(25)26(30)28-19-6-7-29(14-19)24-17-9-15-8-16(11-17)12-18(24)10-15/h2-5,13,15-19,24H,6-12,14H2,1H3,(H,28,30)/t15-,16+,17-,18+,19-,24?/m0/s1 XLNJGZHDQBCQJA-ZHOVQHOQSA-N 50099800 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-adamantan-2-yl-pyrrolidin-3-yl)-amide::CHEMBL52298 D(2) dopamine receptor Rattus norvegicus 5.8 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12084053 103996625 CHEMBL52298 ZINC13862866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179736 COc1c(cc(Br)c2ccccc12)C(=O)NC1CC2CCCC(C1)N2C1CCCCC1 InChI=1S/C26H33BrN2O2/c1-31-25-22-13-6-5-12-21(22)24(27)16-23(25)26(30)28-17-14-19-10-7-11-20(15-17)29(19)18-8-3-2-4-9-18/h5-6,12-13,16-20H,2-4,7-11,14-15H2,1H3,(H,28,30) OBVLIYLZARBQBE-UHFFFAOYSA-N 50099811 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (9-cyclohexyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide::CHEMBL423122 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12084050 103996636 CHEMBL423122 ZINC13862885 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179741 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1CCCCCC1 InChI=1S/C24H31BrN2O2/c1-29-23-20-13-7-6-12-19(20)22(25)15-21(23)24(28)26-16-18-11-8-14-27(18)17-9-4-2-3-5-10-17/h6-7,12-13,15,17-18H,2-5,8-11,14,16H2,1H3,(H,26,28)/t18-/m1/s1 BOSOVNGIOQDIAC-GOSISDBHSA-N 50099796 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cycloheptyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL52300 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10766338 103996621 CHEMBL52300 ZINC13862883 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179744 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1C1C2CCCC1CCC2 InChI=1S/C26H33BrN2O2/c1-31-25-21-13-3-2-12-20(21)23(27)15-22(25)26(30)28-16-19-11-6-14-29(19)24-17-7-4-8-18(24)10-5-9-17/h2-3,12-13,15,17-19,24H,4-11,14,16H2,1H3,(H,28,30)/t17?,18?,19-,24?/m0/s1 OXPSOFUXALIQFQ-MCLLYFMISA-N 50099804 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-bicyclo[3.3.1]non-9-yl-pyrrolidin-2-ylmethyl)-amide::CHEMBL54662 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099804&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10696254 103996629 CHEMBL54662 ZINC13862877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179746 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1C1CCC1 InChI=1S/C21H25BrN2O2/c1-26-20-17-10-3-2-9-16(17)19(22)12-18(20)21(25)23-13-15-8-5-11-24(15)14-6-4-7-14/h2-3,9-10,12,14-15H,4-8,11,13H2,1H3,(H,23,25)/t15-/m0/s1 AFSSAOBKLVREBP-HNNXBMFYSA-N 50099798 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclobutyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL298759 D(2) dopamine receptor Rattus norvegicus 11.8 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099798&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10525997 103996623 CHEMBL298759 ZINC13862873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179748 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1C1CCCCC1 InChI=1S/C23H29BrN2O2/c1-28-22-19-12-6-5-11-18(19)21(24)14-20(22)23(27)25-15-17-10-7-13-26(17)16-8-3-2-4-9-16/h5-6,11-12,14,16-17H,2-4,7-10,13,15H2,1H3,(H,25,27)/t17-/m0/s1 JVVXYJOBIBKLSD-KRWDZBQOSA-N 50099818 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclohexyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL52835 D(2) dopamine receptor Rattus norvegicus 442 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10551313 103996643 CHEMBL52835 ZINC13862875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179751 COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(Cc2ccccc2)C1 InChI=1S/C23H23BrN2O2/c1-28-22-19-10-6-5-9-18(19)21(24)13-20(22)23(27)25-17-11-12-26(15-17)14-16-7-3-2-4-8-16/h2-10,13,17H,11-12,14-15H2,1H3,(H,25,27)/t17-/m1/s1 UBVYCNOXGQYSRQ-QGZVFWFLSA-N 50099814 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((R)-1-benzyl-pyrrolidin-3-yl)-amide::4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-pyrrolidin-3-yl)-amide::CHEMBL298875 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10551026 103996639 CHEMBL298875 ZINC13553240 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179757 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1CCCCC1 InChI=1S/C23H29BrN2O2/c1-28-22-19-12-6-5-11-18(19)21(24)14-20(22)23(27)25-15-17-10-7-13-26(17)16-8-3-2-4-9-16/h5-6,11-12,14,16-17H,2-4,7-10,13,15H2,1H3,(H,25,27)/t17-/m1/s1 JVVXYJOBIBKLSD-QGZVFWFLSA-N 50099815 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((R)-1-cyclohexyl-pyrrolidin-2-ylmethyl)-amide::4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclohexyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL53038 D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599447 103996640 CHEMBL53038 ZINC13862882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179758 COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(C1)C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 InChI=1S/C26H31BrN2O2/c1-31-25-21-5-3-2-4-20(21)23(27)13-22(25)26(30)28-19-6-7-29(14-19)24-17-9-15-8-16(11-17)12-18(24)10-15/h2-5,13,15-19,24H,6-12,14H2,1H3,(H,28,30)/t15-,16+,17-,18+,19-,24?/m1/s1 XLNJGZHDQBCQJA-LJFRYMOQSA-N 50099823 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-adamantan-2-yl-pyrrolidin-3-yl)-amide::CHEMBL51754 D(2) dopamine receptor Rattus norvegicus 62 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12084054 103996648 CHEMBL51754 ZINC13862871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179760 COc1c(cc(Br)c2ccccc12)C(=O)NC1CCN(CC1)C1CCCC1 InChI=1S/C22H27BrN2O2/c1-27-21-18-9-5-4-8-17(18)20(23)14-19(21)22(26)24-15-10-12-25(13-11-15)16-6-2-3-7-16/h4-5,8-9,14-16H,2-3,6-7,10-13H2,1H3,(H,24,26) IBSUSMRNKCYPFQ-UHFFFAOYSA-N 50099820 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclopentyl-piperidin-4-yl)-amide::CHEMBL54092 D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099820&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10582642 103996645 CHEMBL54092 ZINC13862857 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179761 COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CCN(C1)C1CCCC1 InChI=1S/C21H25BrN2O2/c1-26-20-17-9-5-4-8-16(17)19(22)12-18(20)21(25)23-14-10-11-24(13-14)15-6-2-3-7-15/h4-5,8-9,12,14-15H,2-3,6-7,10-11,13H2,1H3,(H,23,25)/t14-/m0/s1 JBWREVQKLWMQCO-AWEZNQCLSA-N 50099812 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclopentyl-pyrrolidin-3-yl)-amide::CHEMBL53778 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099812&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10835756 103996637 CHEMBL53778 ZINC13862862 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179765 COc1c(cc(Br)c2ccccc12)C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C24H25BrN2O2/c1-29-23-20-10-6-5-9-19(20)22(25)15-21(23)24(28)26-18-11-13-27(14-12-18)16-17-7-3-2-4-8-17/h2-10,15,18H,11-14,16H2,1H3,(H,26,28) SUQIESLQCIUEKX-UHFFFAOYSA-N 50099799 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-piperidin-4-yl)-amide::CHEMBL51959 D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10789834 103996624 CHEMBL51959 ZINC13862856 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179769 COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CCN(C1)C1CCCCCC1 InChI=1S/C23H29BrN2O2/c1-28-22-19-11-7-6-10-18(19)21(24)14-20(22)23(27)25-16-12-13-26(15-16)17-8-4-2-3-5-9-17/h6-7,10-11,14,16-17H,2-5,8-9,12-13,15H2,1H3,(H,25,27)/t16-/m0/s1 CJONMKUBCIENBK-INIZCTEOSA-N 50099794 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cycloheptyl-pyrrolidin-3-yl)-amide::CHEMBL54667 D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099794&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9889709 103996619 CHEMBL54667 ZINC13862864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179770 COc1c(cc(Br)c2ccccc12)C(=O)NC1CC2CCCC(C1)N2Cc1ccccc1 InChI=1S/C27H29BrN2O2/c1-32-26-23-13-6-5-12-22(23)25(28)16-24(26)27(31)29-19-14-20-10-7-11-21(15-19)30(20)17-18-8-3-2-4-9-18/h2-6,8-9,12-13,16,19-21H,7,10-11,14-15,17H2,1H3,(H,29,31) JDNRAJORTMVTCX-UHFFFAOYSA-N 50099821 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (9-benzyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide::CHEMBL52588 D(2) dopamine receptor Rattus norvegicus 0.2 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099821&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21846520 103996646 CHEMBL52588 ZINC13862887 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179777 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1CCCC1 InChI=1S/C22H27BrN2O2/c1-27-21-18-11-5-4-10-17(18)20(23)13-19(21)22(26)24-14-16-9-6-12-25(16)15-7-2-3-8-15/h4-5,10-11,13,15-16H,2-3,6-9,12,14H2,1H3,(H,24,26)/t16-/m1/s1 KRQFTVXGLAIKHZ-MRXNPFEDSA-N 50099813 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclopentyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL416481 D(2) dopamine receptor Rattus norvegicus 157 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10550623 103996638 CHEMBL416481 ZINC13862881 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179781 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1CCC1 InChI=1S/C21H25BrN2O2/c1-26-20-17-10-3-2-9-16(17)19(22)12-18(20)21(25)23-13-15-8-5-11-24(15)14-6-4-7-14/h2-3,9-10,12,14-15H,4-8,11,13H2,1H3,(H,23,25)/t15-/m1/s1 AFSSAOBKLVREBP-OAHLLOKOSA-N 50099792 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclobutyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL50517 D(2) dopamine receptor Rattus norvegicus 277 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811875 103996617 CHEMBL50517 ZINC13862880 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179785 COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(C1)C1CCCCC1 InChI=1S/C22H27BrN2O2/c1-27-21-18-10-6-5-9-17(18)20(23)13-19(21)22(26)24-15-11-12-25(14-15)16-7-3-2-4-8-16/h5-6,9-10,13,15-16H,2-4,7-8,11-12,14H2,1H3,(H,24,26)/t15-/m1/s1 UWMANVFYGMUYDW-OAHLLOKOSA-N 50099826 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclohexyl-pyrrolidin-3-yl)-amide::CHEMBL54026 D(2) dopamine receptor Rattus norvegicus 74 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099826&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10741325 103996651 CHEMBL54026 ZINC13862868 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179786 COc1c(cc(Br)c2ccccc12)C(=O)NC1CCN(CC1)C1CCCCC1 InChI=1S/C23H29BrN2O2/c1-28-22-19-10-6-5-9-18(19)21(24)15-20(22)23(27)25-16-11-13-26(14-12-16)17-7-3-2-4-8-17/h5-6,9-10,15-17H,2-4,7-8,11-14H2,1H3,(H,25,27) YPWMABJCFITXHU-UHFFFAOYSA-N 50099808 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclohexyl-piperidin-4-yl)-amide::CHEMBL51856 D(2) dopamine receptor Rattus norvegicus 94 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10789481 103996633 CHEMBL51856 ZINC13862858 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179787 COc1c(cc(Br)c2ccccc12)C(=O)NC1CCN(CC1)C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 InChI=1S/C27H33BrN2O2/c1-32-26-22-5-3-2-4-21(22)24(28)15-23(26)27(31)29-20-6-8-30(9-7-20)25-18-11-16-10-17(13-18)14-19(25)12-16/h2-5,15-20,25H,6-14H2,1H3,(H,29,31)/t16-,17+,18-,19+,25? YRIMPLNXOIKKMH-KAHLFYIYSA-N 50099810 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-adamantan-2-yl-piperidin-4-yl)-amide::CHEMBL50352 D(2) dopamine receptor Rattus norvegicus 96 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12084044 103996635 CHEMBL50352 ZINC13862861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179793 COc1c(cc(Br)c2ccccc12)C(=O)NC1CCN(CC1)C1C2CCCC1CCC2 InChI=1S/C26H33BrN2O2/c1-31-25-21-11-3-2-10-20(21)23(27)16-22(25)26(30)28-19-12-14-29(15-13-19)24-17-6-4-7-18(24)9-5-8-17/h2-3,10-11,16-19,24H,4-9,12-15H2,1H3,(H,28,30) PDTZJFWZZFJDIT-UHFFFAOYSA-N 50099816 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-bicyclo[3.3.1]non-9-yl-piperidin-4-yl)-amide::CHEMBL53401 D(2) dopamine receptor Rattus norvegicus 771 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10582670 103996641 CHEMBL53401 ZINC13862860 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179794 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 InChI=1S/C27H33BrN2O2/c1-32-26-22-7-3-2-6-21(22)24(28)14-23(26)27(31)29-15-20-5-4-8-30(20)25-18-10-16-9-17(12-18)13-19(25)11-16/h2-3,6-7,14,16-20,25H,4-5,8-13,15H2,1H3,(H,29,31)/t16-,17+,18-,19+,20-,25?/m1/s1 NCPWXKOHFJBWEP-NDKMIFBWSA-N 50099805 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-adamantan-2-yl-pyrrolidin-2-ylmethyl)-amide::CHEMBL301929 D(2) dopamine receptor Rattus norvegicus 22.9 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12084056 103996630 CHEMBL301929 ZINC13862884 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179797 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1C1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2 InChI=1S/C27H33BrN2O2/c1-32-26-22-7-3-2-6-21(22)24(28)14-23(26)27(31)29-15-20-5-4-8-30(20)25-18-10-16-9-17(12-18)13-19(25)11-16/h2-3,6-7,14,16-20,25H,4-5,8-13,15H2,1H3,(H,29,31)/t16-,17+,18-,19+,20-,25?/m0/s1 NCPWXKOHFJBWEP-LHHYNMKPSA-N 50099819 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-adamantan-2-yl-pyrrolidin-2-ylmethyl)-amide::CHEMBL53218 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12084055 103996644 CHEMBL53218 ZINC13862878 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179798 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1Cc1ccccc1 InChI=1S/C24H25BrN2O2/c1-29-23-20-12-6-5-11-19(20)22(25)14-21(23)24(28)26-15-18-10-7-13-27(18)16-17-8-3-2-4-9-17/h2-6,8-9,11-12,14,18H,7,10,13,15-16H2,1H3,(H,26,28)/t18-/m1/s1 UGGRLDVMPAOIFF-GOSISDBHSA-N 50099809 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL53102 D(2) dopamine receptor Rattus norvegicus 11.4 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10718492 103996634 CHEMBL53102 ZINC13862879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179801 COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(C1)C1CCCCCC1 InChI=1S/C23H29BrN2O2/c1-28-22-19-11-7-6-10-18(19)21(24)14-20(22)23(27)25-16-12-13-26(15-16)17-8-4-2-3-5-9-17/h6-7,10-11,14,16-17H,2-5,8-9,12-13,15H2,1H3,(H,25,27)/t16-/m1/s1 CJONMKUBCIENBK-MRXNPFEDSA-N 50099803 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cycloheptyl-pyrrolidin-3-yl)-amide::CHEMBL53320 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10741970 103996628 CHEMBL53320 ZINC13862869 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179803 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1C1CCCC1 InChI=1S/C22H27BrN2O2/c1-27-21-18-11-5-4-10-17(18)20(23)13-19(21)22(26)24-14-16-9-6-12-25(16)15-7-2-3-8-15/h4-5,10-11,13,15-16H,2-3,6-9,12,14H2,1H3,(H,24,26)/t16-/m0/s1 KRQFTVXGLAIKHZ-INIZCTEOSA-N 50099795 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclopentyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL54571 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099795&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11796923 103996620 CHEMBL54571 ZINC13862874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179804 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1C1CCCCCC1 InChI=1S/C24H31BrN2O2/c1-29-23-20-13-7-6-12-19(20)22(25)15-21(23)24(28)26-16-18-11-8-14-27(18)17-9-4-2-3-5-10-17/h6-7,12-13,15,17-18H,2-5,8-11,14,16H2,1H3,(H,26,28)/t18-/m0/s1 BOSOVNGIOQDIAC-SFHVURJKSA-N 50099822 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cycloheptyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL301732 D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10790095 103996647 CHEMBL301732 ZINC13862876 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179805 COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(C1)C1C2CCCC1CCC2 InChI=1S/C25H31BrN2O2/c1-30-24-20-11-3-2-10-19(20)22(26)14-21(24)25(29)27-18-12-13-28(15-18)23-16-6-4-7-17(23)9-5-8-16/h2-3,10-11,14,16-18,23H,4-9,12-13,15H2,1H3,(H,27,29)/t16?,17?,18-,23?/m1/s1 SWEOLYDPFYCLRX-NTFGGDPESA-N 50099825 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-bicyclo[3.3.1]non-9-yl-pyrrolidin-3-yl)-amide::CHEMBL301302 D(2) dopamine receptor Rattus norvegicus 75 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099825&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10719189 103996650 CHEMBL301302 ZINC13862870 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179809 COc1c(cc(Br)c2ccccc12)C(=O)N[C@@H]1CCN(C1)C1CCCC1 InChI=1S/C21H25BrN2O2/c1-26-20-17-9-5-4-8-16(17)19(22)12-18(20)21(25)23-14-10-11-24(13-14)15-6-2-3-7-15/h4-5,8-9,12,14-15H,2-3,6-7,10-11,13H2,1H3,(H,23,25)/t14-/m1/s1 JBWREVQKLWMQCO-CQSZACIVSA-N 50099802 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclopentyl-pyrrolidin-3-yl)-amide::CHEMBL54027 D(2) dopamine receptor Rattus norvegicus 283 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645614 103996627 CHEMBL54027 ZINC13862867 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179814 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@@H]1CCCN1Cc1ccccc1 InChI=1S/C24H25BrN2O2/c1-29-23-20-12-6-5-11-19(20)22(25)14-21(23)24(28)26-15-18-10-7-13-27(18)16-17-8-3-2-4-9-17/h2-6,8-9,11-12,14,18H,7,10,13,15-16H2,1H3,(H,26,28)/t18-/m0/s1 UGGRLDVMPAOIFF-SFHVURJKSA-N 50099824 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL53650 D(2) dopamine receptor Rattus norvegicus 151 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099824&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10789833 103996649 CHEMBL53650 ZINC13862872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179815 COc1c(cc(Br)c2ccccc12)C(=O)N[C@H]1CCN(Cc2ccccc2)C1 InChI=1S/C23H23BrN2O2/c1-28-22-19-10-6-5-9-18(19)21(24)13-20(22)23(27)25-17-11-12-26(15-17)14-16-7-3-2-4-8-16/h2-10,13,17H,11-12,14-15H2,1H3,(H,25,27)/t17-/m0/s1 UBVYCNOXGQYSRQ-KRWDZBQOSA-N 50099817 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-benzyl-pyrrolidin-3-yl)-amide::CHEMBL50465 D(2) dopamine receptor Rattus norvegicus 9.7 ChEMBL 10.1021/jm0100077 10.7270/Q2NK3DBZ 11356115 Huang, Y; Luedtke, RR; Freeman, RA; Wu, L; Mach, RH Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10622914 103996642 CHEMBL50465 ZINC13553241 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50179980 COc1ccccc1N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C19H22N4O/c1-24-18-7-3-2-6-17(18)23-11-9-22(10-12-23)14-15-13-21-19-16(15)5-4-8-20-19/h2-8,13H,9-12,14H2,1H3,(H,20,21) IDBBDQXTEVOOKW-UHFFFAOYSA-N 50099890 3-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL435949 D(2) dopamine receptor Rattus norvegicus 438 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10314060 103996715 CHEMBL435949 ZINC28770345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185407 COC(CO)CN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c1-26-16(15-25)14-23-10-12-24(13-11-23)21-17-6-2-4-8-19(17)27-20-9-5-3-7-18(20)22-21/h2-9,16,25H,10-15H2,1H3 VEFWIPJNZIESHB-UHFFFAOYSA-N 50102314 3-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-2-methoxy-propan-1-ol::CHEMBL339889 D(2) dopamine receptor Rattus norvegicus 755 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10810004 103998854 CHEMBL339889 ZINC13861685 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185408 OCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C19H21N3OS/c23-14-13-21-9-11-22(12-10-21)19-15-5-1-3-7-17(15)24-18-8-4-2-6-16(18)20-19/h1-8,23H,9-14H2 OFLMIXVKBNAUIB-UHFFFAOYSA-N 50102315 2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethanol::CHEMBL127823 D(2) dopamine receptor Rattus norvegicus 1330 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102315&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10807021 103998855 CHEMBL127823 ZINC13861677 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185409 OCCOCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C23H29N3O3S/c27-14-16-29-18-17-28-15-13-25-9-11-26(12-10-25)23-19-5-1-3-7-21(19)30-22-8-4-2-6-20(22)24-23/h1-8,27H,9-18H2 JWFSUEASTFEYFJ-UHFFFAOYSA-N 50102316 2-{2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethoxy}-ethanol::CHEMBL341098 D(2) dopamine receptor Rattus norvegicus 1394 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102316&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10764960 103998856 CHEMBL341098 ZINC13861678 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185410 COCC(CO)N1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c1-26-15-16(14-25)23-10-12-24(13-11-23)21-17-6-2-4-8-19(17)27-20-9-5-3-7-18(20)22-21/h2-9,16,25H,10-15H2,1H3 LXKHZIVVODUPIX-UHFFFAOYSA-N 50102317 2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-3-methoxy-propan-1-ol::CHEMBL126540 D(2) dopamine receptor Rattus norvegicus 1640 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102317&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11794379 103998857 CHEMBL126540 ZINC13861687 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185411 OCCOCCN1CCN(CC1)C1=Nc2ccccc2S(=O)(=O)c2ccccc12 InChI=1S/C21H25N3O4S/c25-14-16-28-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)29(26,27)20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 SQUTWXZEWJNIQN-UHFFFAOYSA-N 50102318 2-{2-[4-(5,5-Dioxo-5H-5lambda*6*-dibenzo[b,f][1,4]thiazepin-11-yl)-piperazin-1-yl]-ethoxy}-ethanol::CHEMBL126526 D(2) dopamine receptor Rattus norvegicus 132 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102318&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10788000 103998858 CHEMBL126526 ZINC27302982 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185412 CN1CCN(CC1)C1=Nc2ccc(O)cc2Sc2ccccc12 InChI=1S/C18H19N3OS/c1-20-8-10-21(11-9-20)18-14-4-2-3-5-16(14)23-17-12-13(22)6-7-15(17)19-18/h2-7,12,22H,8-11H2,1H3 DZFBRBNGGYVEGF-UHFFFAOYSA-N 50102319 11-(4-Methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepin-7-ol::CHEMBL126082 D(2) dopamine receptor Rattus norvegicus 49 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10853514 103998859 CHEMBL126082 ZINC13861664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185413 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 132 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185414 OCCOCCN1CCN(CC1)C1=Nc2ccc(O)cc2Sc2ccccc12 InChI=1S/C21H25N3O3S/c25-12-14-27-13-11-23-7-9-24(10-8-23)21-17-3-1-2-4-19(17)28-20-15-16(26)5-6-18(20)22-21/h1-6,15,25-26H,7-14H2 VEGVCHRFYPFJFO-UHFFFAOYSA-N 50102320 11-{4-[2-(2-Hydroxy-ethoxy)-ethyl]-piperazin-1-yl}-dibenzo[b,f][1,4]thiazepin-7-ol::CHEMBL126482 D(2) dopamine receptor Rattus norvegicus 166 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 132203 103998860 CHEMBL126482 ZINC22061171 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185415 C(C1CCCO1)N1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C22H25N3OS/c1-3-9-20-18(7-1)22(23-19-8-2-4-10-21(19)27-20)25-13-11-24(12-14-25)16-17-6-5-15-26-17/h1-4,7-10,17H,5-6,11-16H2 BWMIMNUXQCHAAF-UHFFFAOYSA-N 50102321 11-[4-(Tetrahydro-furan-2-ylmethyl)-piperazin-1-yl]-dibenzo[b,f][1,4]thiazepine::CHEMBL126658 D(2) dopamine receptor Rattus norvegicus 417 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10619728 103998861 CHEMBL126658 ZINC12356208 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185416 COCC(CN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12)OC InChI=1S/C22H27N3O2S/c1-26-16-17(27-2)15-24-11-13-25(14-12-24)22-18-7-3-5-9-20(18)28-21-10-6-4-8-19(21)23-22/h3-10,17H,11-16H2,1-2H3 LHZUERDCLPXCOX-UHFFFAOYSA-N 50102322 11-[4-(2,3-Dimethoxy-propyl)-piperazin-1-yl]-dibenzo[b,f][1,4]thiazepine::CHEMBL338648 D(2) dopamine receptor Rattus norvegicus 795 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102322&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10596975 103998862 CHEMBL338648 ZINC13861681 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185417 OCCOCCN1CCN(CC1)C1=Nc2ccc(F)cc2Sc2ccccc12 InChI=1S/C21H24FN3O2S/c22-16-5-6-18-20(15-16)28-19-4-2-1-3-17(19)21(23-18)25-9-7-24(8-10-25)11-13-27-14-12-26/h1-6,15,26H,7-14H2 KSAGXTGKRZNDFE-UHFFFAOYSA-N 50102323 2-{2-[4-(7-Fluoro-dibenzo[b,f][1,4]thiazepin-11-yl)-piperazin-1-yl]-ethoxy}-ethanol::CHEMBL340225 D(2) dopamine receptor Rattus norvegicus 560 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811052 103998863 CHEMBL340225 ZINC13861674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185418 CN1CCN(CC1)C1=Nc2ccc(F)cc2Sc2ccccc12 InChI=1S/C18H18FN3S/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-16(14)23-17-12-13(19)6-7-15(17)20-18/h2-7,12H,8-11H2,1H3 FNMMIUDLKSABOJ-UHFFFAOYSA-N 50102324 7-Fluoro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::CHEMBL125575 D(2) dopamine receptor Rattus norvegicus 963.0 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10734993 103998864 CHEMBL125575 ZINC13861665 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185419 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Rattus norvegicus 330 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185420 CN1CCN(CC1)C1=Nc2ccccc2Cc2ccccc12 InChI=1S/C19H21N3/c1-21-10-12-22(13-11-21)19-17-8-4-2-6-15(17)14-16-7-3-5-9-18(16)20-19/h2-9H,10-14H2,1H3 PWRPUAKXMQAFCJ-UHFFFAOYSA-N 50102325 6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::CHEMBL340801::Perlapine D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16106 103998865 CHEMBL340801 ZINC27303430 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185421 OCCOCCN1CCN(CC1)C1=Nc2cc(Cl)ccc2Cc2ccccc12 InChI=1S/C22H26ClN3O2/c23-19-6-5-18-15-17-3-1-2-4-20(17)22(24-21(18)16-19)26-9-7-25(8-10-26)11-13-28-14-12-27/h1-6,16,27H,7-15H2 QWBMUFMLNOULHK-UHFFFAOYSA-N 50102327 2-{2-[4-(3-Chloro-11H-dibenzo[b,e]azepin-6-yl)-piperazin-1-yl]-ethoxy}-ethanol::CHEMBL339508 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10787136 103998867 CHEMBL339508 ZINC13861669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185422 COCC(CCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12)OC InChI=1S/C23H29N3O2S/c1-27-17-18(28-2)11-12-25-13-15-26(16-14-25)23-19-7-3-5-9-21(19)29-22-10-6-4-8-20(22)24-23/h3-10,18H,11-17H2,1-2H3 BJVUMFJTYVBRMZ-UHFFFAOYSA-N 50102326 11-[4-(3,4-Dimethoxy-butyl)-piperazin-1-yl]-dibenzo[b,f][1,4]thiazepine::CHEMBL129277 D(2) dopamine receptor Rattus norvegicus 293 ChEMBL 10.1021/jm000242+ 10.7270/Q2639P1N 11462978 Warawa, EJ; Migler, BM; Ohnmacht, CJ; Needles, AL; Gatos, GC; McLaren, FM; Nelson, CL; Kirkland, KM AstraZeneca Pharmaceuticals LP http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795909 103998866 CHEMBL129277 ZINC13861683 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185434 COc1ccccc1N1CCN(CCC(=O)c2csc3ccccc23)CC1 InChI=1S/C22H24N2O2S/c1-26-21-8-4-3-7-19(21)24-14-12-23(13-15-24)11-10-20(25)18-16-27-22-9-5-2-6-17(18)22/h2-9,16H,10-15H2,1H3 VFVYVWQENQPQHA-UHFFFAOYSA-N 50102338 1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one::CHEMBL135878 D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm001059j 10.7270/Q22B8XBC 11462981 Martinez-Esparza, J; Oficialdegui, AM; Perez-Silanes, S; Heras, B; Orus, L; Palop, JA; Lasheras, B; Roca, J; Mourelle, M; Bosch, A; Del Castillo, JC; Tordera, R; Del Rio, J; Monge, A Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9842861 103998878 CHEMBL135878 ZINC53204472 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50180015 Fc1ccccc1N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19FN4/c19-16-5-1-2-6-17(16)23-10-8-22(9-11-23)13-14-12-21-18-15(14)4-3-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) OOKNJSVAHXTYKL-UHFFFAOYSA-N 50099887 3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL282424 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099887&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22065997 103996712 CHEMBL282424 ZINC28769079 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50180027 CSc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C19H22N4S/c1-24-17-6-4-16(5-7-17)23-11-9-22(10-12-23)14-15-13-21-19-18(15)3-2-8-20-19/h2-8,13H,9-12,14H2,1H3,(H,20,21) TYDSNTMUQPPTLL-UHFFFAOYSA-N 50099892 3-[4-(4-Methylsulfanyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL28651 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099892&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020040 103996717 CHEMBL28651 ZINC28770080 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50180032 COc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C19H22N4O/c1-24-17-6-4-16(5-7-17)23-11-9-22(10-12-23)14-15-13-21-19-18(15)3-2-8-20-19/h2-8,13H,9-12,14H2,1H3,(H,20,21) NNGCXJPRHBHODU-UHFFFAOYSA-N 50075360 3-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL28607 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50075360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50075360&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9905249 103968499 CHEMBL28607 ZINC28771301 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50180034 C=Cc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C20H22N4/c1-2-16-5-7-18(8-6-16)24-12-10-23(11-13-24)15-17-14-22-20-19(17)4-3-9-21-20/h2-9,14H,1,10-13,15H2,(H,21,22) HGWVDBLPHYBBTH-UHFFFAOYSA-N 50099889 3-[4-(4-Vinyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL29808 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099889&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44278115 103996714 CHEMBL29808 ZINC28769047 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50180048 FC(F)(F)c1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C19H19F3N4/c20-19(21,22)15-3-5-16(6-4-15)26-10-8-25(9-11-26)13-14-12-24-18-17(14)2-1-7-23-18/h1-7,12H,8-11,13H2,(H,23,24) BFQIOOYNLCWKIJ-UHFFFAOYSA-N 50099891 3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL283036 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099891&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19958494 103996716 CHEMBL283036 ZINC53084151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185489 COc1ccccc1N1CCN(CCC(O)c2csc3ccccc23)CC1 InChI=1S/C22H26N2O2S/c1-26-21-8-4-3-7-19(21)24-14-12-23(13-15-24)11-10-20(25)18-16-27-22-9-5-2-6-17(18)22/h2-9,16,20,25H,10-15H2,1H3 BXLSCEOVEPCFSC-UHFFFAOYSA-N 50102359 1-(benzo[b]thiophen-3-yl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propan-1-ol::1-Benzo[b]thiophen-3-yl-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-ol::CHEMBL136936 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm001059j 10.7270/Q22B8XBC 11462981 Martinez-Esparza, J; Oficialdegui, AM; Perez-Silanes, S; Heras, B; Orus, L; Palop, JA; Lasheras, B; Roca, J; Mourelle, M; Bosch, A; Del Castillo, JC; Tordera, R; Del Rio, J; Monge, A Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102359&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9886269 103998899 CHEMBL136936 ZINC12356220 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50180062 CCCc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C21H26N4/c1-2-4-17-6-8-19(9-7-17)25-13-11-24(12-14-25)16-18-15-23-21-20(18)5-3-10-22-21/h3,5-10,15H,2,4,11-14,16H2,1H3,(H,22,23) QRQZDZPCRVUFNL-UHFFFAOYSA-N 50099894 3-[4-(4-Propyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL28833 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099894&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44278114 103996719 CHEMBL28833 ZINC28769981 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50180071 Fc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19FN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) HNCAIEASLRMRKM-UHFFFAOYSA-N 50099893 3-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL28997 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099893&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10267394 103996718 CHEMBL28997 ZINC53045062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50180186 C(N1CCN(CC1)c1ccc(cc1)-c1ccccc1)c1c[nH]c2ncccc12 InChI=1S/C24H24N4/c1-2-5-19(6-3-1)20-8-10-22(11-9-20)28-15-13-27(14-16-28)18-21-17-26-24-23(21)7-4-12-25-24/h1-12,17H,13-16,18H2,(H,25,26) KGZWRXWYLPRJCF-UHFFFAOYSA-N 50099895 3-(4-Biphenyl-4-yl-piperazin-1-ylmethyl)-1H-pyrrolo[2,3-b]pyridine::CHEMBL287671 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099895&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44278111 103996720 CHEMBL287671 ZINC28769976 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50185616 COc1ccccc1N1CCN(CCC(Oc2cccc3ccccc23)c2ccsc2)CC1 InChI=1S/C28H30N2O2S/c1-31-28-11-5-4-10-25(28)30-18-16-29(17-19-30)15-13-26(23-14-20-33-21-23)32-27-12-6-8-22-7-2-3-9-24(22)27/h2-12,14,20-21,26H,13,15-19H2,1H3 FCNUZSYKUANYNY-UHFFFAOYSA-N 50102346 1-(2-Methoxy-phenyl)-4-[3-(naphthalen-1-yloxy)-3-thiophen-3-yl-propyl]-piperazine::1-(2-methoxyphenyl)-4-(3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propyl)piperazine::CHEMBL134743 D(2) dopamine receptor Rattus norvegicus 2500 ChEMBL 10.1021/jm001059j 10.7270/Q22B8XBC 11462981 Martinez-Esparza, J; Oficialdegui, AM; Perez-Silanes, S; Heras, B; Orus, L; Palop, JA; Lasheras, B; Roca, J; Mourelle, M; Bosch, A; Del Castillo, JC; Tordera, R; Del Rio, J; Monge, A Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10095692 103998886 CHEMBL134743 ZINC13861760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50180193 Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C18H19ClN4/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18/h1-7,12H,8-11,13H2,(H,20,21) OGJGQVFWEPNYSB-UHFFFAOYSA-N 85093 CAS_3853::CHEMBL267014::CHEMBL555670::L 745,870::NSC_3853 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search L74 6IQL 5311200 136351193 CHEMBL555670CHEMBL267014 3303 ZINC25760037 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50180203 CCc1ccc(cc1)N1CCN(Cc2c[nH]c3ncccc23)CC1 InChI=1S/C20H24N4/c1-2-16-5-7-18(8-6-16)24-12-10-23(11-13-24)15-17-14-22-20-19(17)4-3-9-21-20/h3-9,14H,2,10-13,15H2,1H3,(H,21,22) FKHBXKAEVUTBRK-UHFFFAOYSA-N 50099888 3-[4-(4-Ethyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL282829 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(01)00241-4 10.7270/Q28C9VHC 11378358 Huang, Y; Kegeles, LS; Bae, S; Hwang, D; Roth, BL; Savage, JE; Laruelle, M Columbia University College of Physicians and Surgeons http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19958507 103996713 CHEMBL282829 ZINC28770344 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50178174 COc1nsnc1N1CCN(C[C@@H](Cc2cccnc2)NC(=O)C2(C)CCCCC2)CC1 InChI=1S/C23H34N6O2S/c1-23(8-4-3-5-9-23)22(30)25-19(15-18-7-6-10-24-16-18)17-28-11-13-29(14-12-28)20-21(31-2)27-32-26-20/h6-7,10,16,19H,3-5,8-9,11-15,17H2,1-2H3,(H,25,30)/t19-/m1/s1 SWKBPFACSXLZFM-LJQANCHMSA-N 50099011 1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-methoxy-[1,2,5]thiadiazol-3-yl)-piperazin-1-yl]-1-pyridin-3-ylmethyl-ethyl}-amide::CHEMBL266393 D(2) dopamine receptor Rattus norvegicus 3516 ChEMBL 10.1016/s0960-894x(01)00151-2 10.7270/Q2SJ1JWX 11327592 Sabb, AL; Vogel, RL; Kelly, MG; Palmer, Y; Smith, DL; Andree, TH; Schechter, LE Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099011&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9868793 103995942 CHEMBL266393 ZINC52541673 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50174941 ClC1=COc2ccccc2C(=O)N1CCCCN1CCC(=CC1)c1ccccn1 InChI=1S/C23H24ClN3O2/c24-22-17-29-21-9-2-1-7-19(21)23(28)27(22)14-6-5-13-26-15-10-18(11-16-26)20-8-3-4-12-25-20/h1-4,7-10,12,17H,5-6,11,13-16H2 URMTUEWUIGOJBW-UHFFFAOYSA-N 50097342 3-Chloro-4-[4-(3',6'-dihydro-2'H-[2,4']bipyridinyl-1'-yl)-butyl]-4H-benzo[f][1,4]oxazepin-5-one::CHEMBL345237 D(2) dopamine receptor Rattus norvegicus 84 ChEMBL 10.1016/s0960-894x(01)00008-7 10.7270/Q2P26XDB 11229779 Kamei, K; Maeda, N; Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Suntory Biomedical Research Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9801640 103994674 CHEMBL345237 ZINC01892462 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50174942 ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H24ClN5O2/c22-19-16-29-18-7-2-1-6-17(18)20(28)27(19)11-4-3-10-25-12-14-26(15-13-25)21-23-8-5-9-24-21/h1-2,5-9,16H,3-4,10-15H2 MTXWTNUNMLDZTE-UHFFFAOYSA-N 50097343 3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-4H-benzo[f][1,4]oxazepin-5-one::CHEMBL347167 D(2) dopamine receptor Rattus norvegicus 199 ChEMBL 10.1016/s0960-894x(01)00008-7 10.7270/Q2P26XDB 11229779 Kamei, K; Maeda, N; Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Suntory Biomedical Research Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18327916 103994675 CHEMBL347167 ZINC27648485 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50174947 CC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C22H27N5O2/c1-18-17-29-20-8-3-2-7-19(20)21(28)27(18)12-5-4-11-25-13-15-26(16-14-25)22-23-9-6-10-24-22/h2-3,6-10,17H,4-5,11-16H2,1H3 OHIMWQXBTPNPOS-UHFFFAOYSA-N 50097345 3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-4H-benzo[f][1,4]oxazepin-5-one::CHEMBL352029 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1016/s0960-894x(01)00008-7 10.7270/Q2P26XDB 11229779 Kamei, K; Maeda, N; Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Suntory Biomedical Research Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18328103 103994677 CHEMBL352029 ZINC27652922 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50174949 ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ccccn1 InChI=1S/C22H25ClN4O2/c23-20-17-29-19-8-2-1-7-18(19)22(28)27(20)12-6-5-11-25-13-15-26(16-14-25)21-9-3-4-10-24-21/h1-4,7-10,17H,5-6,11-16H2 XIOIYDRBYJBMKK-UHFFFAOYSA-N 50097341 3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-butyl]-4H-benzo[f][1,4]oxazepin-5-one::CHEMBL357266 D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1016/s0960-894x(01)00008-7 10.7270/Q2P26XDB 11229779 Kamei, K; Maeda, N; Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Suntory Biomedical Research Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15490956 103994673 CHEMBL357266 ZINC27648061 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50174950 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1016/s0960-894x(01)00008-7 10.7270/Q2P26XDB 11229779 Kamei, K; Maeda, N; Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Suntory Biomedical Research Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202439 Cn1c2ccc(CCCCN3CCC(CC3)c3ccccc3)cc2sc1=O InChI=1S/C23H28N2OS/c1-24-21-11-10-18(17-22(21)27-23(24)26)7-5-6-14-25-15-12-20(13-16-25)19-8-3-2-4-9-19/h2-4,8-11,17,20H,5-7,12-16H2,1H3 HNSXISBJVADGBQ-UHFFFAOYSA-N 50111632 3-Methyl-6-[4-(4-phenyl-piperidin-1-yl)-butyl]-3H-benzothiazol-2-one::CHEMBL15986 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111632&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10339767 104006170 CHEMBL15986 ZINC13440622 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202440 Cn1c2ccc(CCN3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)cc2sc1=O InChI=1S/C21H23Cl2N3OS/c1-24-19-5-3-15(13-20(19)28-21(24)27)6-7-25-8-10-26(11-9-25)14-16-2-4-17(22)18(23)12-16/h2-5,12-13H,6-11,14H2,1H3 NUAABSUTOZGFHF-UHFFFAOYSA-N 50111634 6-{2-[4-(3,4-Dichloro-benzyl)-piperazin-1-yl]-ethyl}-3-methyl-3H-benzothiazol-2-one::CHEMBL15601 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111634&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17867054 104006172 CHEMBL15601 ZINC22445766 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202442 Cn1c2ccc(CCCCN3CCN(Cc4ccc(Cl)cc4Cl)CC3)cc2sc1=O InChI=1S/C23H27Cl2N3OS/c1-26-21-8-5-17(14-22(21)30-23(26)29)4-2-3-9-27-10-12-28(13-11-27)16-18-6-7-19(24)15-20(18)25/h5-8,14-15H,2-4,9-13,16H2,1H3 BHVDELPYDQJPHR-UHFFFAOYSA-N 50111633 6-{4-[4-(2,4-Dichloro-benzyl)-piperazin-1-yl]-butyl}-3-methyl-3H-benzothiazol-2-one::CHEMBL15637 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111633&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24835442 104006171 CHEMBL15637 ZINC22924640 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202445 Cn1c2ccc(CCN3CCN(Cc4ccccc4)CC3)cc2sc1=O InChI=1S/C21H25N3OS/c1-22-19-8-7-17(15-20(19)26-21(22)25)9-10-23-11-13-24(14-12-23)16-18-5-3-2-4-6-18/h2-8,15H,9-14,16H2,1H3 KIBTUVSBDSDCNM-UHFFFAOYSA-N 50111627 6-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-3-methyl-3H-benzothiazol-2-one::CHEMBL15955 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111627&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15288693 104006165 CHEMBL15955 ZINC22924636 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202452 Cn1c2ccc(CCN3CCC(Cc4ccccc4)CC3)cc2sc1=O InChI=1S/C22H26N2OS/c1-23-20-8-7-18(16-21(20)26-22(23)25)9-12-24-13-10-19(11-14-24)15-17-5-3-2-4-6-17/h2-8,16,19H,9-15H2,1H3 PAQOLVFJAVGSLY-UHFFFAOYSA-N 50111631 6-[2-(4-Benzyl-piperidin-1-yl)-ethyl]-3-methyl-3H-benzothiazol-2-one::CHEMBL15809 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111631&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10361564 104006169 CHEMBL15809 ZINC00836242 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202456 Cn1c2ccc(CCCCN3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)cc2sc1=O InChI=1S/C23H27Cl2N3OS/c1-26-21-8-6-17(15-22(21)30-23(26)29)4-2-3-9-27-10-12-28(13-11-27)16-18-5-7-19(24)20(25)14-18/h5-8,14-15H,2-4,9-13,16H2,1H3 HXCDEZDRGXIHKK-UHFFFAOYSA-N 50111628 6-{4-[4-(3,4-Dichloro-benzyl)-piperazin-1-yl]-butyl}-3-methyl-3H-benzothiazol-2-one::CHEMBL15456 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111628&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10027435 104006166 CHEMBL15456 ZINC22924645 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202464 Cn1c2ccc(CCN3CCC(CC3)c3ccccc3)cc2sc1=O InChI=1S/C21H24N2OS/c1-22-19-8-7-16(15-20(19)25-21(22)24)9-12-23-13-10-18(11-14-23)17-5-3-2-4-6-17/h2-8,15,18H,9-14H2,1H3 JCYAYKQSZYSTGG-UHFFFAOYSA-N 50111626 3-Methyl-6-[2-(4-phenyl-piperidin-1-yl)-ethyl]-3H-benzothiazol-2-one::CHEMBL415985 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111626&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9863340 104006164 CHEMBL415985 ZINC00836243 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202465 C[C@H]1CN(CCc2ccc3n(C)c(=O)sc3c2)C[C@@H](C)N1 InChI=1S/C16H23N3OS/c1-11-9-19(10-12(2)17-11)7-6-13-4-5-14-15(8-13)21-16(20)18(14)3/h4-5,8,11-12,17H,6-7,9-10H2,1-3H3/t11-,12+ JJZCOPQZNMJSKH-TXEJJXNPSA-N 50111635 6-[2-((3R,5S)-3,5-Dimethyl-piperazin-1-yl)-ethyl]-3-methyl-3H-benzothiazol-2-one::CHEMBL15499 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111635&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44270248 104006173 CHEMBL15499 ZINC22924650 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202483 Cn1c2ccc(CCCCN3CCN(Cc4ccccc4)CC3)cc2sc1=O InChI=1S/C23H29N3OS/c1-24-21-11-10-19(17-22(21)28-23(24)27)7-5-6-12-25-13-15-26(16-14-25)18-20-8-3-2-4-9-20/h2-4,8-11,17H,5-7,12-16,18H2,1H3 PFEUKVRZIQOBBQ-UHFFFAOYSA-N 50111625 6-[4-(4-Benzyl-piperazin-1-yl)-butyl]-3-methyl-3H-benzothiazol-2-one::CHEMBL15941 D(2) dopamine receptor Rattus norvegicus 10000 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111625&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22413499 104006163 CHEMBL15941 ZINC19364398 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202501 Cn1c2ccc(CCN3CCN(Cc4ccc(Cl)cc4Cl)CC3)cc2sc1=O InChI=1S/C21H23Cl2N3OS/c1-24-19-5-2-15(12-20(19)28-21(24)27)6-7-25-8-10-26(11-9-25)14-16-3-4-17(22)13-18(16)23/h2-5,12-13H,6-11,14H2,1H3 IVPBWXCQFBOUNC-UHFFFAOYSA-N 50111629 6-{2-[4-(2,4-Dichloro-benzyl)-piperazin-1-yl]-ethyl}-3-methyl-3H-benzothiazol-2-one::CHEMBL280063 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111629&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17867053 104006167 CHEMBL280063 ZINC22445761 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202502 Cn1c2ccc(CCCCN3CCC(Cc4ccccc4)CC3)cc2sc1=O InChI=1S/C24H30N2OS/c1-25-22-11-10-20(18-23(22)28-24(25)27)9-5-6-14-26-15-12-21(13-16-26)17-19-7-3-2-4-8-19/h2-4,7-8,10-11,18,21H,5-6,9,12-17H2,1H3 ZBVBPDNSLDPENM-UHFFFAOYSA-N 50111630 6-[4-(4-Benzyl-piperidin-1-yl)-butyl]-3-methyl-3H-benzothiazol-2-one::CHEMBL16123 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111630&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21474204 104006168 CHEMBL16123 ZINC13440624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50202505 C[C@H]1CN(CCCCc2ccc3n(C)c(=O)sc3c2)C[C@@H](C)N1 InChI=1S/C18H27N3OS/c1-13-11-21(12-14(2)19-13)9-5-4-6-15-7-8-16-17(10-15)23-18(22)20(16)3/h7-8,10,13-14,19H,4-6,9,11-12H2,1-3H3/t13-,14+ WWHQUUWBFSSVDA-OKILXGFUSA-N 50111624 6-[4-((3R,5S)-3,5-Dimethyl-piperazin-1-yl)-butyl]-3-methyl-3H-benzothiazol-2-one::CHEMBL280088 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1016/s0960-894x(02)00123-3 10.7270/Q2G44PM6 11934576 Mouithys-Mickalad, A; Poupaert, JH; Spampinato, S; Lesieur, D Université de Lille 2 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111624&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44270247 104006162 CHEMBL280088 ZINC22924654 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50197032 COC1Cc2ccccc2C2(CCN(CCCc3ccccc3)CC2)O1 InChI=1S/C23H29NO2/c1-25-22-18-20-11-5-6-12-21(20)23(26-22)13-16-24(17-14-23)15-7-10-19-8-3-2-4-9-19/h2-6,8-9,11-12,22H,7,10,13-18H2,1H3 IJKYJDDNDXAREJ-UHFFFAOYSA-N 50108654 1-[3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]-1-yl]-3-phenylpropane::CHEMBL138458 D(2) dopamine receptor Rattus norvegicus 1600 ChEMBL 10.1021/jm010992z 10.7270/Q2VT1RDH 11784148 Maier, CA; Wunsch, B Pharmazeutisches Institut der Universität Freiburg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108654&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10915140 104003836 CHEMBL138458 ZINC13472041 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50197038 COC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 InChI=1S/C21H25NO2/c1-23-20-15-18-9-5-6-10-19(18)21(24-20)11-13-22(14-12-21)16-17-7-3-2-4-8-17/h2-10,20H,11-16H2,1H3 POOPPNNSPMKABZ-UHFFFAOYSA-N 50108653 1'-benzyl-3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]::1'-benzyl-3-methoxyspiro[isochroman-1,4'-piperidine]::CHEMBL141209 D(2) dopamine receptor Rattus norvegicus 5900 ChEMBL 10.1021/jm010992z 10.7270/Q2VT1RDH 11784148 Maier, CA; Wunsch, B Pharmazeutisches Institut der Universität Freiburg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108653&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10019102 104003835 CHEMBL141209 ZINC13472033 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50197084 COC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc12 InChI=1S/C20H23NO2/c1-22-19-17-9-5-6-10-18(17)20(23-19)11-13-21(14-12-20)15-16-7-3-2-4-8-16/h2-10,19H,11-15H2,1H3 RZZAEVQHACUOGI-UHFFFAOYSA-N 50108659 1'-benzyl-3-methoxy-3H-spiro[2-benzofuran-1,4'-piperidine]::1'-benzyl-3-methoxy-3H-spiro[isobenzofuran-1,4'-piperidine]::1'-benzyl-3-methoxyspiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]::CHEMBL138809 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm010992z 10.7270/Q2VT1RDH 11784148 Maier, CA; Wunsch, B Pharmazeutisches Institut der Universität Freiburg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108659&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357986 104003841 CHEMBL138809 ZINC13472062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195134 CCCN(CCc1ccccc1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C22H29NO2/c1-4-11-23(12-10-17-8-6-5-7-9-17)20-13-18-15-21(24-2)22(25-3)16-19(18)14-20/h5-9,15-16,20H,4,10-14H2,1-3H3 SDGBWVJSVFKSFY-UHFFFAOYSA-N 50107869 (5,6-Dimethoxy-indan-2-yl)-phenethyl-propyl-amine::CHEMBL440819 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10871514 104003097 CHEMBL440819 ZINC13471423 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195135 CCCN(CCC)C1Cc2cccc(O)c2C1 InChI=1S/C15H23NO/c1-3-8-16(9-4-2)13-10-12-6-5-7-15(17)14(12)11-13/h5-7,13,17H,3-4,8-11H2,1-2H3 CJKPENGZQFFKLK-UHFFFAOYSA-N 50107867 (R)-2-Dipropylamino-indan-4-ol::(S)-2-Dipropylamino-indan-4-ol::2-Dipropylamino-indan-4-ol::CHEMBL85362 D(2) dopamine receptor Rattus norvegicus 5.2 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 146855 104003095 CHEMBL85362 ZINC05833150 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195140 CCCN(CCc1ccsc1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C20H27NO2S/c1-4-7-21(8-5-15-6-9-24-14-15)18-10-16-12-19(22-2)20(23-3)13-17(16)11-18/h6,9,12-14,18H,4-5,7-8,10-11H2,1-3H3 QFFWSYBNWWOHJV-UHFFFAOYSA-N 50107874 (5,6-Dimethoxy-indan-2-yl)-propyl-(2-thiophen-3-yl-ethyl)-amine::CHEMBL142481 D(2) dopamine receptor Rattus norvegicus 61 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10882507 104003102 CHEMBL142481 ZINC13471420 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195143 CCCN(CCC)C1Cc2cccc(OC)c2C1 InChI=1S/C16H25NO/c1-4-9-17(10-5-2)14-11-13-7-6-8-16(18-3)15(13)12-14/h6-8,14H,4-5,9-12H2,1-3H3 UJEXCOYXKFZVRX-UHFFFAOYSA-N 50107877 (4-Methoxy-indan-2-yl)-dipropyl-amine::CHEMBL421936 D(2) dopamine receptor Rattus norvegicus 4.2 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107877&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11021227 104003105 CHEMBL421936 ZINC13471356 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195146 CCCN(CCc1ccc(OC)cc1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C23H31NO3/c1-5-11-24(12-10-17-6-8-21(25-2)9-7-17)20-13-18-15-22(26-3)23(27-4)16-19(18)14-20/h6-9,15-16,20H,5,10-14H2,1-4H3 LVJNVXHDJDZJGN-UHFFFAOYSA-N 50107878 (5,6-Dimethoxy-indan-2-yl)-[2-(4-methoxy-phenyl)-ethyl]-propyl-amine::CHEMBL142154 D(2) dopamine receptor Rattus norvegicus 163 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107878&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10893955 104003106 CHEMBL142154 ZINC13471430 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195147 CCCN(CCc1ccc(cc1)C(F)(F)F)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C23H28F3NO2/c1-4-10-27(11-9-16-5-7-19(8-6-16)23(24,25)26)20-12-17-14-21(28-2)22(29-3)15-18(17)13-20/h5-8,14-15,20H,4,9-13H2,1-3H3 WTDNZXBSHAXHEU-UHFFFAOYSA-N 50107879 (5,6-Dimethoxy-indan-2-yl)-propyl-[2-(4-trifluoromethyl-phenyl)-ethyl]-amine::CHEMBL344524 D(2) dopamine receptor Rattus norvegicus 310 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107879&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11080039 104003107 CHEMBL344524 ZINC13471434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195149 CCCN(CCc1cccc(F)c1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C22H28FNO2/c1-4-9-24(10-8-16-6-5-7-19(23)11-16)20-12-17-14-21(25-2)22(26-3)15-18(17)13-20/h5-7,11,14-15,20H,4,8-10,12-13H2,1-3H3 NXLPPGJOKAJXLI-UHFFFAOYSA-N 50107881 (5,6-Dimethoxy-indan-2-yl)-[2-(3-fluoro-phenyl)-ethyl]-propyl-amine::CHEMBL142835 D(2) dopamine receptor Rattus norvegicus 125 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107881&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10893673 104003109 CHEMBL142835 ZINC13471426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195154 CCCN(CCc1cccnc1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C21H28N2O2/c1-4-9-23(10-7-16-6-5-8-22-15-16)19-11-17-13-20(24-2)21(25-3)14-18(17)12-19/h5-6,8,13-15,19H,4,7,9-12H2,1-3H3 BGCJDPYLWUEEJR-UHFFFAOYSA-N 50107872 (5,6-Dimethoxy-indan-2-yl)-propyl-(2-pyridin-3-yl-ethyl)-amine::CHEMBL143509 D(2) dopamine receptor Rattus norvegicus 286 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11046089 104003100 CHEMBL143509 ZINC13471440 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195156 CCCN(Cc1ccsc1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C19H25NO2S/c1-4-6-20(12-14-5-7-23-13-14)17-8-15-10-18(21-2)19(22-3)11-16(15)9-17/h5,7,10-11,13,17H,4,6,8-9,12H2,1-3H3 PJPXNQMIBHMNFN-UHFFFAOYSA-N 50107884 (5,6-Dimethoxy-indan-2-yl)-propyl-thiophen-3-ylmethyl-amine::CHEMBL142976 D(2) dopamine receptor Rattus norvegicus 1244 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11045807 104003112 CHEMBL142976 ZINC13471414 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195159 CCCN(CCC)C1Cc2ccc(O)cc2C1 InChI=1S/C15H23NO/c1-3-7-16(8-4-2)14-9-12-5-6-15(17)11-13(12)10-14/h5-6,11,14,17H,3-4,7-10H2,1-2H3 CGVTXQCPDIZHAI-UHFFFAOYSA-N 50107870 2-Dipropylamino-indan-5-ol::CHEMBL16409 D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12728243 104003098 CHEMBL16409 ZINC13471353 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195162 CCCN(CCCF)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C17H26FNO2/c1-4-7-19(8-5-6-18)15-9-13-11-16(20-2)17(21-3)12-14(13)10-15/h11-12,15H,4-10H2,1-3H3 GKMPOKJUCTTXEA-UHFFFAOYSA-N 50107885 (5,6-Dimethoxy-indan-2-yl)-(3-fluoro-propyl)-propyl-amine::CHEMBL423371 D(2) dopamine receptor Rattus norvegicus 1840 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10880968 104003113 CHEMBL423371 ZINC13471401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195163 CCCN(CCCc1ccccc1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C23H31NO2/c1-4-12-24(13-8-11-18-9-6-5-7-10-18)21-14-19-16-22(25-2)23(26-3)17-20(19)15-21/h5-7,9-10,16-17,21H,4,8,11-15H2,1-3H3 HQRKZFCEXOHQII-UHFFFAOYSA-N 50107882 (5,6-Dimethoxy-indan-2-yl)-(3-phenyl-propyl)-propyl-amine::CHEMBL142197 D(2) dopamine receptor Rattus norvegicus 155 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107882&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11078716 104003110 CHEMBL142197 ZINC13471442 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195165 CCCN(CCC)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C17H27NO2/c1-5-7-18(8-6-2)15-9-13-11-16(19-3)17(20-4)12-14(13)10-15/h11-12,15H,5-10H2,1-4H3 UOLJKAPABHXFRE-UHFFFAOYSA-N 50107876 (5,6-Dimethoxy-indan-2-yl)-dipropyl-amine::CHEMBL16410::PNU-99194A D(2) dopamine receptor Rattus norvegicus 992 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107876&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5626 104003104 CHEMBL16410 ZINC00007459 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195166 CCCN(CCc1ccc(Br)cc1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C22H28BrNO2/c1-4-10-24(11-9-16-5-7-19(23)8-6-16)20-12-17-14-21(25-2)22(26-3)15-18(17)13-20/h5-8,14-15,20H,4,9-13H2,1-3H3 VDMXQMKKYAQTLW-UHFFFAOYSA-N 50107883 CHEMBL142535::[2-(4-Bromo-phenyl)-ethyl]-(5,6-dimethoxy-indan-2-yl)-propyl-amine D(2) dopamine receptor Rattus norvegicus 97 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107883&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10971805 104003111 CHEMBL142535 ZINC13471428 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195167 CCCN(CCC)C1Cc2ccc(OC)cc2C1 InChI=1S/C16H25NO/c1-4-8-17(9-5-2)15-10-13-6-7-16(18-3)12-14(13)11-15/h6-7,12,15H,4-5,8-11H2,1-3H3 IZHPDJHRNYGLPC-UHFFFAOYSA-N 50107875 (5-Methoxy-indan-2-yl)-dipropyl-amine::CHEMBL356823 D(2) dopamine receptor Rattus norvegicus 263 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107875&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11139462 104003103 CHEMBL356823 ZINC13471361 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195168 CCCN(CCc1cccc(N)c1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C22H30N2O2/c1-4-9-24(10-8-16-6-5-7-19(23)11-16)20-12-17-14-21(25-2)22(26-3)15-18(17)13-20/h5-7,11,14-15,20H,4,8-10,12-13,23H2,1-3H3 OAIKERJNHAYFDQ-UHFFFAOYSA-N 50107886 CHEMBL142163::[2-(3-Amino-phenyl)-ethyl]-(5,6-dimethoxy-indan-2-yl)-propyl-amine D(2) dopamine receptor Rattus norvegicus 162 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107886&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10861170 104003114 CHEMBL142163 ZINC13471436 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195172 CCCN(CCc1csc(N)n1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C19H27N3O2S/c1-4-6-22(7-5-15-12-25-19(20)21-15)16-8-13-10-17(23-2)18(24-3)11-14(13)9-16/h10-12,16H,4-9H2,1-3H3,(H2,20,21) BRFFPGSHDFIFKS-UHFFFAOYSA-N 50107880 4-{2-[(5,6-Dimethoxy-indan-2-yl)-propyl-amino]-ethyl}-thiazol-2-ylamine::CHEMBL141614 D(2) dopamine receptor Rattus norvegicus 265 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107880&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10970462 104003108 CHEMBL141614 ZINC13471439 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195173 CCCN(CCc1ccc(OC)c(OC)c1)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C24H33NO4/c1-6-10-25(11-9-17-7-8-21(26-2)22(12-17)27-3)20-13-18-15-23(28-4)24(29-5)16-19(18)14-20/h7-8,12,15-16,20H,6,9-11,13-14H2,1-5H3 PMEYCKNESWKUMY-UHFFFAOYSA-N 50107873 (5,6-Dimethoxy-indan-2-yl)-[2-(3,4-dimethoxy-phenyl)-ethyl]-propyl-amine::CHEMBL142056 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107873&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11825516 104003101 CHEMBL142056 ZINC13471432 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195174 CCCN(CC)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C16H25NO2/c1-5-7-17(6-2)14-8-12-10-15(18-3)16(19-4)11-13(12)9-14/h10-11,14H,5-9H2,1-4H3 HQRJDVRCEULSCC-UHFFFAOYSA-N 50107888 (5,6-Dimethoxy-indan-2-yl)-ethyl-propyl-amine::CHEMBL142684 D(2) dopamine receptor Rattus norvegicus 374.0 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11010820 104003116 CHEMBL142684 ZINC13471376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50195175 CCCN(CCc1ccc(cc1)C(N)=O)C1Cc2cc(OC)c(OC)cc2C1 InChI=1S/C23H30N2O3/c1-4-10-25(11-9-16-5-7-17(8-6-16)23(24)26)20-12-18-14-21(27-2)22(28-3)15-19(18)13-20/h5-8,14-15,20H,4,9-13H2,1-3H3,(H2,24,26) POOHFULDFIUDII-UHFFFAOYSA-N 50107868 4-{2-[(5,6-Dimethoxy-indan-2-yl)-propyl-amino]-ethyl}-benzamide::CHEMBL142956 D(2) dopamine receptor Rattus norvegicus 123 ChEMBL 10.1021/jm010145w 10.7270/Q2ZP45D5 11741489 Haadsma-Svensson, SR; Cleek, KA; Dinh, DM; Duncan, JN; Haber, CL; Huff, RM; Lajiness, ME; Nichols, NF; Smith, MW; Svensson, KA; Zaya, MJ; Carlsson, A; Lin, CH Pharmacia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107868&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11728676 104003096 CHEMBL142956 ZINC13471438 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194245 COc1cccc2c(CCCN3CCN(CC3)c3ccccn3)cccc12 InChI=1S/C23H27N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-5,7,9-13H,6,8,14-18H2,1H3 XTICRBGKPDRHCR-UHFFFAOYSA-N 50107234 1-[3-(5-Methoxy-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL139505 D(2) dopamine receptor Rattus norvegicus 450 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107234&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11046644 104002655 CHEMBL139505 ZINC13470670 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194249 COc1ccc2CC(CNCCOc3ccccn3)CCc2c1 InChI=1S/C19H24N2O2/c1-22-18-8-7-16-12-15(5-6-17(16)13-18)14-20-10-11-23-19-4-2-3-9-21-19/h2-4,7-9,13,15,20H,5-6,10-12,14H2,1H3 XRIKYXQUZSHDJV-UHFFFAOYSA-N 50107237 (6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-[2-(pyridin-2-yloxy)-ethyl]-amine::CHEMBL138899 D(2) dopamine receptor Rattus norvegicus >850 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107237&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11758776 104002658 CHEMBL138899 ZINC13470686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194252 COc1cccc(c1)C1=CCC(CC1)N1CCN(CC1)c1ccccc1OC InChI=1S/C24H30N2O2/c1-27-22-7-5-6-20(18-22)19-10-12-21(13-11-19)25-14-16-26(17-15-25)23-8-3-4-9-24(23)28-2/h3-10,18,21H,11-17H2,1-2H3 WNELYPHBVMGNQP-UHFFFAOYSA-N 50107239 1-(2-Methoxy-phenyl)-4-[4-(3-methoxy-phenyl)-cyclohex-3-enyl]-piperazine::CHEMBL138892 D(2) dopamine receptor Rattus norvegicus 2930 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107239&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11003366 104002660 CHEMBL138892 ZINC13470704 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194262 COc1cccc(CCCCN2CCN(CC2)c2ccccn2)c1 InChI=1S/C20H27N3O/c1-24-19-9-6-8-18(17-19)7-3-5-12-22-13-15-23(16-14-22)20-10-2-4-11-21-20/h2,4,6,8-11,17H,3,5,7,12-16H2,1H3 UYALMDJMDUJNMA-UHFFFAOYSA-N 50107245 1-[4-(3-Methoxy-phenyl)-butyl]-4-pyridin-2-yl-piperazine::CHEMBL344146 D(2) dopamine receptor Rattus norvegicus 750 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107245&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11809531 104002666 CHEMBL344146 ZINC13470674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194266 COc1cccc2c(CCCNCCOc3ccccn3)cccc12 InChI=1S/C21H24N2O2/c1-24-20-11-5-9-18-17(7-4-10-19(18)20)8-6-13-22-15-16-25-21-12-2-3-14-23-21/h2-5,7,9-12,14,22H,6,8,13,15-16H2,1H3 DFNUNBHMMOZMON-UHFFFAOYSA-N 50107235 CHEMBL138109::[3-(5-Methoxy-naphthalen-1-yl)-propyl]-[2-(pyridin-2-yloxy)-ethyl]-amine D(2) dopamine receptor Rattus norvegicus 378.0 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107235&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11782656 104002656 CHEMBL138109 ZINC13470672 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194276 COc1cccc2\C(CCCc12)=C\CCN1CCN(CC1)c1ccccn1 InChI=1S/C23H29N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-3,5,8-9,11-13H,4,6-7,10,14-18H2,1H3/b19-8+ MEJDASWPPCVZOR-UFWORHAWSA-N 50033843 1-[3-(5-Methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)-propyl]-4-pyridin-2-yl-piperazine::1-{3-[5-Methoxy-3,4-dihydro-2H-naphthalen-(1E)-ylidene]-propyl}-4-pyridin-2-yl-piperazine::CHEMBL140406 D(2) dopamine receptor Rattus norvegicus 125 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10248163 103942091 CHEMBL140406 ZINC13470666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194277 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.8 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194282 COc1cccc2\C(CCCc12)=C\CCNCCOc1ccccn1 InChI=1S/C21H26N2O2/c1-24-20-11-5-9-18-17(7-4-10-19(18)20)8-6-13-22-15-16-25-21-12-2-3-14-23-21/h2-3,5,8-9,11-12,14,22H,4,6-7,10,13,15-16H2,1H3/b17-8+ YFOSHVNQFAEBLL-CAOOACKPSA-N 50107250 CHEMBL136563::[3-(5-Methoxy-3,4-dihydro-2H-naphthalen-1-ylidene)-propyl]-[2-(pyridin-2-yloxy)-ethyl]-amine D(2) dopamine receptor Rattus norvegicus >850 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020030 104002671 CHEMBL136563 ZINC13470668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50205288 Fc1ccc(cc1)C(=O)C1CCN(CCc2cccc(I)c2)CC1 InChI=1S/C20H21FINO/c21-18-6-4-16(5-7-18)20(24)17-9-12-23(13-10-17)11-8-15-2-1-3-19(22)14-15/h1-7,14,17H,8-13H2 QJFCDRQWMDZIGI-UHFFFAOYSA-N 50113325 (4-Fluoro-phenyl)-{1-[2-(3-iodo-phenyl)-ethyl]-piperidin-4-yl}-methanone::CHEMBL306478 D(2) dopamine receptor Rattus norvegicus 51.8 ChEMBL 10.1021/jm0200411 10.7270/Q2B27TM2 12014970 Fu, X; Tan, PZ; Kula, NS; Baldessarini, R; Tamagnan, G; Innis, RB; Baldwin, RM Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11729823 104007674 CHEMBL306478 ZINC13473853 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194301 COc1cccc(c1)C1=CCC(CC1)N1CCN(CC1)c1cccc2ccccc12 InChI=1S/C27H30N2O/c1-30-25-9-4-8-23(20-25)21-12-14-24(15-13-21)28-16-18-29(19-17-28)27-11-5-7-22-6-2-3-10-26(22)27/h2-12,20,24H,13-19H2,1H3 COSIKLPCGWBEMS-UHFFFAOYSA-N 50107252 1-[4-(3-Methoxy-phenyl)-cyclohex-3-enyl]-4-naphthalen-1-yl-piperazine::CHEMBL138289 D(2) dopamine receptor Rattus norvegicus 327 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107252&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10862233 104002673 CHEMBL138289 ZINC13470709 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194305 COc1ccc2CCC(CCN3CCN(CC3)c3ccccn3)Cc2c1 InChI=1S/C22H29N3O/c1-26-21-8-7-19-6-5-18(16-20(19)17-21)9-11-24-12-14-25(15-13-24)22-4-2-3-10-23-22/h2-4,7-8,10,17-18H,5-6,9,11-16H2,1H3 MQYILSGYILZXMS-UHFFFAOYSA-N 50107249 1-[2-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-ethyl]-4-pyridin-2-yl-piperazine::CHEMBL423181 D(2) dopamine receptor Rattus norvegicus 1730 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10948133 104002670 CHEMBL423181 ZINC13470691 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194322 COc1cccc2C(CCCN3CCN(CC3)c3ccccn3)CCCc12 InChI=1S/C23H31N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-3,5,9,11-13,19H,4,6-8,10,14-18H2,1H3 KKPMYWNQZNRGIK-UHFFFAOYSA-N 50033852 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL444590 D(2) dopamine receptor Rattus norvegicus 117 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10474042 103942100 CHEMBL444590 ZINC13470658 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194338 COc1cccc(CCCCNCCOc2ccccn2)c1 InChI=1S/C18H24N2O2/c1-21-17-9-6-8-16(15-17)7-2-4-11-19-13-14-22-18-10-3-5-12-20-18/h3,5-6,8-10,12,15,19H,2,4,7,11,13-14H2,1H3 KNABGQWLUPBQHM-UHFFFAOYSA-N 50107246 CHEMBL139146::[4-(3-Methoxy-phenyl)-butyl]-[2-(pyridin-2-yloxy)-ethyl]-amine D(2) dopamine receptor Rattus norvegicus >850 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107246&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10935482 104002667 CHEMBL139146 ZINC13470676 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194341 COc1cccc2C(CCCNCCOc3ccccn3)CCCc12 InChI=1S/C21H28N2O2/c1-24-20-11-5-9-18-17(7-4-10-19(18)20)8-6-13-22-15-16-25-21-12-2-3-14-23-21/h2-3,5,9,11-12,14,17,22H,4,6-8,10,13,15-16H2,1H3 HETKYUVAGHVYTA-UHFFFAOYSA-N 50107240 CHEMBL344432::[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-[2-(pyridin-2-yloxy)-ethyl]-amine D(2) dopamine receptor Rattus norvegicus >850 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44358574 104002661 CHEMBL344432 ZINC13470663 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194343 COc1cccc(c1)C1=CCC(CC1)N1CCN(CC1)c1ccccc1 InChI=1S/C23H28N2O/c1-26-23-9-5-6-20(18-23)19-10-12-22(13-11-19)25-16-14-24(15-17-25)21-7-3-2-4-8-21/h2-10,18,22H,11-17H2,1H3 MCVMARUOYHWORW-UHFFFAOYSA-N 50107251 1-(4-(3-methoxyphenyl)cyclohex-3-enyl)-4-phenylpiperazine::1-[4-(3-Methoxy-phenyl)-cyclohex-3-enyl]-4-phenyl-piperazine::CHEMBL139848 D(2) dopamine receptor Rattus norvegicus 2190 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11068038 104002672 CHEMBL139848 ZINC13470699 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194351 COc1cccc(c1)C1=CCC(CC1)N1CCN(CC1)c1ccccn1 InChI=1S/C22H27N3O/c1-26-21-6-4-5-19(17-21)18-8-10-20(11-9-18)24-13-15-25(16-14-24)22-7-2-3-12-23-22/h2-8,12,17,20H,9-11,13-16H2,1H3 DQBQKYJWMSLVPS-UHFFFAOYSA-N 50107247 1-(4-(3-methoxyphenyl)cyclohex-3-enyl)-4-(pyridin-2-yl)piperazine::1-[4-(3-Methoxy-phenyl)-cyclohex-3-enyl]-4-pyridin-2-yl-piperazine::CHEMBL140287 D(2) dopamine receptor Rattus norvegicus 1220 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10948076 104002668 CHEMBL140287 ZINC13470695 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50194356 COc1ccc2CC(CN3CCN(CC3)c3ccccn3)CCc2c1 InChI=1S/C21H27N3O/c1-25-20-8-7-18-14-17(5-6-19(18)15-20)16-23-10-12-24(13-11-23)21-4-2-3-9-22-21/h2-4,7-9,15,17H,5-6,10-14,16H2,1H3 UQISWIRNAUDVMP-UHFFFAOYSA-N 50107253 1-((6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)methyl)-4-(pyridin-2-yl)piperazine::1-(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-4-pyridin-2-yl-piperazine::CHEMBL138900 D(2) dopamine receptor Rattus norvegicus >850 ChEMBL 10.1021/jm010866v 10.7270/Q2NC60GV 11728188 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Lacivita, E; Tortorella, V; Leonardi, A; Poggesi, E; Testa, R Università Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107253&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11002234 104002674 CHEMBL138900 ZINC13470682 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50205312 OC(C1CCN(CCc2ccccc2I)CC1)c1ccc(F)cc1 InChI=1S/C20H23FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17,20,24H,9-14H2 UGKMIYGDPWUKLG-UHFFFAOYSA-N 50113330 (4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-piperidin-4-yl}-methanol::CHEMBL77855 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm0200411 10.7270/Q2B27TM2 12014970 Fu, X; Tan, PZ; Kula, NS; Baldessarini, R; Tamagnan, G; Innis, RB; Baldwin, RM Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10994400 104007679 CHEMBL77855 ZINC13473856 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50205319 Fc1ccc(CCN2CCC(CC2)C(=O)c2ccc(F)cc2)cc1 InChI=1S/C20H21F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17H,9-14H2 IHYHXNKLWLTICM-UHFFFAOYSA-N 50113326 (4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanone::CHEMBL78218 D(2) dopamine receptor Rattus norvegicus 453.0 ChEMBL 10.1021/jm0200411 10.7270/Q2B27TM2 12014970 Fu, X; Tan, PZ; Kula, NS; Baldessarini, R; Tamagnan, G; Innis, RB; Baldwin, RM Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10991109 104007675 CHEMBL78218 ZINC13473865 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50205329 OC(C1CCN(CCc2ccc(F)cc2)CC1)c1ccc(F)cc1 InChI=1S/C20H23F2NO/c21-18-5-1-15(2-6-18)9-12-23-13-10-17(11-14-23)20(24)16-3-7-19(22)8-4-16/h1-8,17,20,24H,9-14H2 KLCDGLISRKLICJ-UHFFFAOYSA-N 50113329 (4-Fluoro-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol::CHEMBL420010 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm0200411 10.7270/Q2B27TM2 12014970 Fu, X; Tan, PZ; Kula, NS; Baldessarini, R; Tamagnan, G; Innis, RB; Baldwin, RM Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113329&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10042333 104007678 CHEMBL420010 ZINC13473864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50205332 Fc1ccc(cc1)C(=O)C1CCN(CCc2ccccc2I)CC1 InChI=1S/C20H21FINO/c21-18-7-5-16(6-8-18)20(24)17-10-13-23(14-11-17)12-9-15-3-1-2-4-19(15)22/h1-8,17H,9-14H2 JREBTSVEMYTHEU-UHFFFAOYSA-N 50113331 (4-Fluoro-phenyl)-{1-[2-(2-iodo-phenyl)-ethyl]-piperidin-4-yl}-methanone::CHEMBL74756 D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm0200411 10.7270/Q2B27TM2 12014970 Fu, X; Tan, PZ; Kula, NS; Baldessarini, R; Tamagnan, G; Innis, RB; Baldwin, RM Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113331&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11016205 104007680 CHEMBL74756 ZINC13473852 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50205341 Fc1ccc(cc1)C(=O)C1CCN(CCc2ccc(I)cc2)CC1 InChI=1S/C20H21FINO/c21-18-5-3-16(4-6-18)20(24)17-10-13-23(14-11-17)12-9-15-1-7-19(22)8-2-15/h1-8,17H,9-14H2 CHWGPAKCKQJKJN-UHFFFAOYSA-N 50113324 (4-Fluoro-phenyl)-{1-[2-(4-iodo-phenyl)-ethyl]-piperidin-4-yl}-methanone::CHEMBL73979 D(2) dopamine receptor Rattus norvegicus 176 ChEMBL 10.1021/jm0200411 10.7270/Q2B27TM2 12014970 Fu, X; Tan, PZ; Kula, NS; Baldessarini, R; Tamagnan, G; Innis, RB; Baldwin, RM Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10873805 104007673 CHEMBL73979 ZINC13473854 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50211104 CCCN1CCc2nn3ccccc3c2C1 InChI=1S/C13H17N3/c1-2-7-15-9-6-12-11(10-15)13-5-3-4-8-16(13)14-12/h3-5,8H,2,6-7,9-10H2,1H3 URWBDIMBZFWGSF-UHFFFAOYSA-N 50116765 3-Propyl-1,2,3,4-tetrahydro-3,8a,9-triaza-fluorene::CHEMBL80845 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116765&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44316315 104010404 CHEMBL80845 ZINC12355903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50211108 CCCN[C@H]1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1 FASDKYOPVNHBLU-ZETCQYMHSA-N 50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570 D(2) dopamine receptor Rattus norvegicus 9.2 ChEMBL 10.1016/s0960-894x(02)00390-6 10.7270/Q2Z89BRG 12161137 Lober, S; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 119570 104010405 8356 CHEMBL301265 DB00413 ZINC03781664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50209176 COc1cccc2Cc3ccccc3[C@@H]3CN(C)CCN3c12 InChI=1S/C19H22N2O/c1-20-10-11-21-17(13-20)16-8-4-3-6-14(16)12-15-7-5-9-18(22-2)19(15)21/h3-9,17H,10-13H2,1-2H3/t17-/m0/s1 GZXNMNCAWGIAAW-KRWDZBQOSA-N 50115640 (-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,4a-diaza-tribenzo[a,c,e]cycloheptene::CHEMBL113238 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm010566d 10.7270/Q28051ZZ 12109911 Wikstrom, HV; Mensonides-Harsema, MM; Cremers, TI; Moltzen, EK; Arnt, J University Center for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115640&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11033734 104009528 CHEMBL113238 ZINC13475061 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50209185 CN1CCN2C(C1)c1ccccc1Cc1cccnc21 InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3 RONZAEMNMFQXRA-UHFFFAOYSA-N 50115644 (+/-)-12-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::2-methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene::CHEMBL654::MIRTAZAPINE::ORG 3770::REMERON D(2) dopamine receptor Rattus norvegicus 1460 ChEMBL 10.1021/jm010566d 10.7270/Q28051ZZ 12109911 Wikstrom, HV; Mensonides-Harsema, MM; Cremers, TI; Moltzen, EK; Arnt, J University Center for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4205 104009532 6950 CHEMBL654 DB00370 7241 C07570 ZINC19702119 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50209203 COc1cccc2Cc3ccccc3C3CN(C)CCN3c12 InChI=1S/C19H22N2O/c1-20-10-11-21-17(13-20)16-8-4-3-6-14(16)12-15-7-5-9-18(22-2)19(15)21/h3-9,17H,10-13H2,1-2H3 GZXNMNCAWGIAAW-UHFFFAOYSA-N 50115643 (+/-)-6 5-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,4a-diaza-tribenzo[a,c,e]cycloheptene::CHEMBL324270 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm010566d 10.7270/Q28051ZZ 12109911 Wikstrom, HV; Mensonides-Harsema, MM; Cremers, TI; Moltzen, EK; Arnt, J University Center for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9882594 104009531 CHEMBL324270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50209229 COc1cccc2Cc3ccccc3[C@H]3CN(C)CCN3c12 InChI=1S/C19H22N2O/c1-20-10-11-21-17(13-20)16-8-4-3-6-14(16)12-15-7-5-9-18(22-2)19(15)21/h3-9,17H,10-13H2,1-2H3/t17-/m1/s1 GZXNMNCAWGIAAW-QGZVFWFLSA-N 50115642 (+)-65-Methoxy-2-methyl-1,2,3,4,9,13b-hexahydro-2,4a-diaza-tribenzo[a,c,e]cycloheptene::CHEMBL111184 D(2) dopamine receptor Rattus norvegicus 460 ChEMBL 10.1021/jm010566d 10.7270/Q28051ZZ 12109911 Wikstrom, HV; Mensonides-Harsema, MM; Cremers, TI; Moltzen, EK; Arnt, J University Center for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10924369 104009530 CHEMBL111184 ZINC13475062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50209236 Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H YNPFMWCWRVTGKJ-UHFFFAOYSA-N 31005 2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine::MIANSERIN HYDROCHLORIDE::MLS000069681::SMR000058472::cid_68551 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm010566d 10.7270/Q28051ZZ 12109911 Wikstrom, HV; Mensonides-Harsema, MM; Cremers, TI; Moltzen, EK; Arnt, J University Center for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31005&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68551 242052839 ZINC00000504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50221730 OC1(CCC(CC1)N1CCN(Cc2ccccc2)CC1)c1ccc2OCOc2c1 InChI=1S/C24H30N2O3/c27-24(20-6-7-22-23(16-20)29-18-28-22)10-8-21(9-11-24)26-14-12-25(13-15-26)17-19-4-2-1-3-5-19/h1-7,16,21,27H,8-15,17-18H2 QWOWPFGONZKUAH-UHFFFAOYSA-N 50122415 1-Benzo[1,3]dioxol-5-yl-4-(4-benzyl-piperazin-1-yl)-cyclohexanol::CHEMBL100875 D(2) dopamine receptor Rattus norvegicus 1700 ChEMBL 10.1016/s0960-894x(02)00879-x 10.7270/Q2251HJQ 12482441 Mattson, RJ; Catt, JD; Sloan, CP; Gao, Q; Carter, RB; Gentile, A; Mahle, CD; Matos, FF; McGovern, R; VanderMaelen, CP; Yocca, FD Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122415&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15233110 104015086 CHEMBL100875 ZINC22442535 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50221736 COc1cccc(CN2CCN(CC2)C2CCC(O)(CC2)c2ccc3OCOc3c2)c1 InChI=1S/C25H32N2O4/c1-29-22-4-2-3-19(15-22)17-26-11-13-27(14-12-26)21-7-9-25(28,10-8-21)20-5-6-23-24(16-20)31-18-30-23/h2-6,15-16,21,28H,7-14,17-18H2,1H3 OSVMSQACZRYAPT-UHFFFAOYSA-N 50122411 1-Benzo[1,3]dioxol-5-yl-4-[4-(3-methoxy-benzyl)-piperazin-1-yl]-cyclohexanol::CHEMBL100086 D(2) dopamine receptor Rattus norvegicus 4800 ChEMBL 10.1016/s0960-894x(02)00879-x 10.7270/Q2251HJQ 12482441 Mattson, RJ; Catt, JD; Sloan, CP; Gao, Q; Carter, RB; Gentile, A; Mahle, CD; Matos, FF; McGovern, R; VanderMaelen, CP; Yocca, FD Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122411&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9845261 104015082 CHEMBL100086 ZINC22926636 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50211768 Oc1ccc2[C@@H]3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2/t13-/m0/s1 ZQTSNGJHMUKLOM-ZDUSSCGKSA-N 50117181 (S)-2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL124561::Dinapsoline, (+/-)::Dinapsoline, (R)(+) D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm0101545 10.7270/Q28K78FR 12166939 Sit, SY; Xie, K; Jacutin-Porte, S; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Wong, H; Zhu, J; Krishnananthan, S; Gao, Q; Verdoorn, T; Johnson, G Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816455 104010781 CHEMBL124561 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50211770 Oc1ccc2[C@H]3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2/t13-/m1/s1 ZQTSNGJHMUKLOM-CYBMUJFWSA-N 50117183 2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL123642::Dinapsoline, (S)(-) D(2) dopamine receptor Rattus norvegicus 1500 ChEMBL 10.1021/jm0101545 10.7270/Q28K78FR 12166939 Sit, SY; Xie, K; Jacutin-Porte, S; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Wong, H; Zhu, J; Krishnananthan, S; Gao, Q; Verdoorn, T; Johnson, G Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10923047 104010783 CHEMBL123642 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50211771 Oc1ccc2C3CNCc4cccc(Cc2c1O)c34 InChI=1S/C16H15NO2/c18-14-5-4-11-12(16(14)19)6-9-2-1-3-10-7-17-8-13(11)15(9)10/h1-5,13,17-19H,6-8H2 ZQTSNGJHMUKLOM-UHFFFAOYSA-N 50117182 2,3,7,11b-Tetrahydro-1H-dibenzo[de,h]isoquinoline-8,9-diol::CHEMBL120995::Dinapsoline, (+/-) D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1021/jm0101545 10.7270/Q28K78FR 12166939 Sit, SY; Xie, K; Jacutin-Porte, S; Taber, MT; Gulwadi, AG; Korpinen, CD; Burris, KD; Molski, TF; Ryan, E; Xu, C; Wong, H; Zhu, J; Krishnananthan, S; Gao, Q; Verdoorn, T; Johnson, G Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50117182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50117182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5249490 104010782 CHEMBL120995 ZINC12355964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235451 Clc1cccc(N2CCN(CCCNC(=O)C3c4ccccc4-c4ccccc34)CC2)c1Cl InChI=1S/C27H27Cl2N3O/c28-23-11-5-12-24(26(23)29)32-17-15-31(16-18-32)14-6-13-30-27(33)25-21-9-3-1-7-19(21)20-8-2-4-10-22(20)25/h1-5,7-12,25H,6,13-18H2,(H,30,33) LIOYKDHOQLNTTQ-UHFFFAOYSA-N 50104142 9H-Fluorene-9-carboxylic acid {3-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL68860 D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104142&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11812838 104000125 CHEMBL68860 ZINC13534332 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235454 Clc1cccc(N2CCN(C\C=C\CNC(=O)c3ccccc3)CC2)c1Cl InChI=1S/C21H23Cl2N3O/c22-18-9-6-10-19(20(18)23)26-15-13-25(14-16-26)12-5-4-11-24-21(27)17-7-2-1-3-8-17/h1-10H,11-16H2,(H,24,27)/b5-4+ DHOCETPWLQILEE-SNAWJCMRSA-N 50129433 CHEMBL71327::N-{(E)-4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-benzamide::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-benzamide D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10001256 104021016 CHEMBL71327 ZINC13534412 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235455 Fc1ccc2[nH]c(cc2c1)C(=O)NCCCCN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C23H25Cl2FN4O/c24-18-4-3-5-21(22(18)25)30-12-10-29(11-13-30)9-2-1-8-27-23(31)20-15-16-14-17(26)6-7-19(16)28-20/h3-7,14-15,28H,1-2,8-13H2,(H,27,31) IMCPEGAWOYJDMH-UHFFFAOYSA-N 50129425 5-Fluoro-1H-indole-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL68740::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-5-fluoro-1H-indole-2-carboxamide D(2) dopamine receptor Rattus norvegicus 83 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129425&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309876 104021008 CHEMBL68740 ZINC13534380 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235456 Clc1cccc(N2CCN(CCCCCN3C(=O)c4ccccc4C3=O)CC2)c1Cl InChI=1S/C23H25Cl2N3O2/c24-19-9-6-10-20(21(19)25)27-15-13-26(14-16-27)11-4-1-5-12-28-22(29)17-7-2-3-8-18(17)23(28)30/h2-3,6-10H,1,4-5,11-16H2 HZMBQYFOWZCHKD-UHFFFAOYSA-N 50104133 2-{5-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-pentyl}-isoindole-1,3-dione::CHEMBL306672 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104133&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10983150 104000116 CHEMBL306672 ZINC13534368 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235458 Clc1cccc(N2CCN(C\C=C\CNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl InChI=1S/C28H27Cl2N3O/c29-25-8-5-9-26(27(25)30)33-16-14-32(15-17-33)13-4-3-12-31-28(34)21-10-11-24-22(19-21)18-20-6-1-2-7-23(20)24/h1-11,19H,12-18H2,(H,31,34)/b4-3+ ZCTVOGWWMHRQLN-ONEGZZNKSA-N 50129429 9H-Fluorene-2-carboxylic acid {(E)-4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide::9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide::CHEMBL304605::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)but-2-enyl)-9H-fluorene-2-carboxamide D(2) dopamine receptor Rattus norvegicus 198 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129429&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309775 104021012 CHEMBL304605 ZINC13534401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235461 Clc1cccc(N2CCN(CCCNC(=O)c3cccc4C(=O)c5ccccc5-c34)CC2)c1Cl InChI=1S/C27H25Cl2N3O2/c28-22-10-4-11-23(25(22)29)32-16-14-31(15-17-32)13-5-12-30-27(34)21-9-3-8-20-24(21)18-6-1-2-7-19(18)26(20)33/h1-4,6-11H,5,12-17H2,(H,30,34) CVJYJKRPDVXLEY-UHFFFAOYSA-N 50104129 9-Oxo-9H-fluorene-4-carboxylic acid {3-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL309118 D(2) dopamine receptor Rattus norvegicus 153 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11762743 104000112 CHEMBL309118 ZINC13534342 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235462 Clc1cccc(N2CCN(CC#CCNC(=O)c3cccc4Cc5ccccc5-c34)CC2)c1Cl InChI=1S/C28H25Cl2N3O/c29-24-11-6-12-25(27(24)30)33-17-15-32(16-18-33)14-4-3-13-31-28(34)23-10-5-8-21-19-20-7-1-2-9-22(20)26(21)23/h1-2,5-12H,13-19H2,(H,31,34) IYDGVRYZQGNOLM-UHFFFAOYSA-N 50129427 9H-Fluorene-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-ynyl}-amide::CHEMBL71416 D(2) dopamine receptor Rattus norvegicus 891 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309604 104021010 CHEMBL71416 ZINC13534421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235468 Nc1ccc2Cc3cccc(C(=O)NCCCCN4CCN(CC4)c4cccc(Cl)c4Cl)c3-c2c1 InChI=1S/C28H30Cl2N4O/c29-24-7-4-8-25(27(24)30)34-15-13-33(14-16-34)12-2-1-11-32-28(35)22-6-3-5-20-17-19-9-10-21(31)18-23(19)26(20)22/h3-10,18H,1-2,11-17,31H2,(H,32,35) PEMDADNXFPDJPI-UHFFFAOYSA-N 50129438 6-Amino-9H-fluorene-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL71502 D(2) dopamine receptor Rattus norvegicus 79 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309898 104021021 CHEMBL71502 ZINC13534376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235470 Clc1cccc(N2CCN(CCCCNC(=O)c3cnc4ccccc4n3)CC2)c1Cl InChI=1S/C23H25Cl2N5O/c24-17-6-5-9-21(22(17)25)30-14-12-29(13-15-30)11-4-3-10-26-23(31)20-16-27-18-7-1-2-8-19(18)28-20/h1-2,5-9,16H,3-4,10-15H2,(H,26,31) WKAAYYBBGYEZQQ-UHFFFAOYSA-N 50129432 CHEMBL262724::Quinoxaline-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 109 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129432&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309509 104021015 CHEMBL262724 ZINC13534384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235471 Clc1cccc(N2CCN(CCCCNC(=O)c3cccc4Cc5ccccc5-c34)CC2)c1Cl InChI=1S/C28H29Cl2N3O/c29-24-11-6-12-25(27(24)30)33-17-15-32(16-18-33)14-4-3-13-31-28(34)23-10-5-8-21-19-20-7-1-2-9-22(20)26(21)23/h1-2,5-12H,3-4,13-19H2,(H,31,34) DOSHKUUCMXQODO-UHFFFAOYSA-N 50129434 9H-Fluorene-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL305294 D(2) dopamine receptor Rattus norvegicus 134 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309601 104021017 CHEMBL305294 ZINC13534372 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235473 Clc1cccc(N2CCN(C\C=C/CNC(=O)c3ccccc3)CC2)c1Cl InChI=1S/C21H23Cl2N3O/c22-18-9-6-10-19(20(18)23)26-15-13-25(14-16-26)12-5-4-11-24-21(27)17-7-2-1-3-8-17/h1-10H,11-16H2,(H,24,27)/b5-4- DHOCETPWLQILEE-PLNGDYQASA-N 50129430 CHEMBL71865::N-{(Z)-4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-benzamide D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129430&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9887463 104021013 CHEMBL71865 ZINC13534416 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235474 Clc1cccc(N2CCN(C\C=C/CNC(=O)c3cccc4Cc5ccccc5-c34)CC2)c1Cl InChI=1S/C28H27Cl2N3O/c29-24-11-6-12-25(27(24)30)33-17-15-32(16-18-33)14-4-3-13-31-28(34)23-10-5-8-21-19-20-7-1-2-9-22(20)26(21)23/h1-12H,13-19H2,(H,31,34)/b4-3- LFQZHAKGDXWDRR-ARJAWSKDSA-N 50129439 9H-Fluorene-4-carboxylic acid {(Z)-4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide::CHEMBL305019 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309675 104021022 CHEMBL305019 ZINC13534397 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235475 Clc1cccc(N2CCN(CC#CCNC(=O)c3ccccc3)CC2)c1Cl InChI=1S/C21H21Cl2N3O/c22-18-9-6-10-19(20(18)23)26-15-13-25(14-16-26)12-5-4-11-24-21(27)17-7-2-1-3-8-17/h1-3,6-10H,11-16H2,(H,24,27) NZDBRYJVPWCALT-UHFFFAOYSA-N 50129435 CHEMBL71783::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-ynyl}-benzamide D(2) dopamine receptor Rattus norvegicus 1700 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129435&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309602 104021018 CHEMBL71783 ZINC13534429 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235479 O=C(NCCCN1CCN(CC1)c1ccccc1)C1c2ccccc2-c2ccccc12 InChI=1S/C27H29N3O/c31-27(26-24-13-6-4-11-22(24)23-12-5-7-14-25(23)26)28-15-8-16-29-17-19-30(20-18-29)21-9-2-1-3-10-21/h1-7,9-14,26H,8,15-20H2,(H,28,31) SNZILXJFTMMHEQ-UHFFFAOYSA-N 50104121 9H-Fluorene-9-carboxylic acid [3-(4-phenyl-piperazin-1-yl)-propyl]-amide::CHEMBL302796 D(2) dopamine receptor Rattus norvegicus 1020 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11133385 104000104 CHEMBL302796 ZINC13534327 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235481 Clc1cccc(N2CCN(CCCCN3C(=O)c4ccccc4C3=O)CC2)c1Cl InChI=1S/C22H23Cl2N3O2/c23-18-8-5-9-19(20(18)24)26-14-12-25(13-15-26)10-3-4-11-27-21(28)16-6-1-2-7-17(16)22(27)29/h1-2,5-9H,3-4,10-15H2 SGVBRIHFEULKBC-UHFFFAOYSA-N 50104125 2-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione::CHEMBL69717 D(2) dopamine receptor Rattus norvegicus 102 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104125&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11812065 104000108 CHEMBL69717 ZINC13534364 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235485 Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)cc3)CC2)c1Cl InChI=1S/C21H24Cl2IN3O/c22-18-4-3-5-19(20(18)23)27-14-12-26(13-15-27)11-2-1-10-25-21(28)16-6-8-17(24)9-7-16/h3-9H,1-2,10-15H2,(H,25,28) UKOYDIULRIOVQF-UHFFFAOYSA-N 50129428 CHEMBL302374::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-4-iodo-benzamide::Quinoxaline-1-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 88 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129428&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309510 104021011 CHEMBL302374 ZINC26288566 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235487 Clc1cccc(N2CCN(C\C=C\CNC(=O)c3cccc4Cc5ccccc5-c34)CC2)c1Cl InChI=1S/C28H27Cl2N3O/c29-24-11-6-12-25(27(24)30)33-17-15-32(16-18-33)14-4-3-13-31-28(34)23-10-5-8-21-19-20-7-1-2-9-22(20)26(21)23/h1-12H,13-19H2,(H,31,34)/b4-3+ LFQZHAKGDXWDRR-ONEGZZNKSA-N 50129431 9H-Fluorene-4-carboxylic acid {(E)-4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide::9H-Fluorene-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide::CHEMBL69571 D(2) dopamine receptor Rattus norvegicus 106 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309688 104021014 CHEMBL69571 ZINC13534393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235488 Clc1cccc(N2CCN(CCCCCNC(=O)c3cccc4C(=O)c5ccccc5-c34)CC2)c1Cl InChI=1S/C29H29Cl2N3O2/c30-24-12-7-13-25(27(24)31)34-18-16-33(17-19-34)15-5-1-4-14-32-29(36)23-11-6-10-22-26(23)20-8-2-3-9-21(20)28(22)35/h2-3,6-13H,1,4-5,14-19H2,(H,32,36) HTQLYZCPYPEYGO-UHFFFAOYSA-N 50104130 9-Oxo-9H-fluorene-4-carboxylic acid {5-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-pentyl}-amide::CHEMBL68720 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104130&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11005852 104000113 CHEMBL68720 ZINC13534351 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235490 Clc1cccc(N2CCN(CCCCNC(=O)C3c4ccccc4-c4ccccc34)CC2)c1Cl InChI=1S/C28H29Cl2N3O/c29-24-12-7-13-25(27(24)30)33-18-16-32(17-19-33)15-6-5-14-31-28(34)26-22-10-3-1-8-20(22)21-9-2-4-11-23(21)26/h1-4,7-13,26H,5-6,14-19H2,(H,31,34) QCKWKKZGPZWWFN-UHFFFAOYSA-N 50104140 9H-Fluorene-9-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL307800 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104140&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10885524 104000123 CHEMBL307800 ZINC13534337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235491 Clc1cccc(N2CCN(CC#CCNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl InChI=1S/C28H25Cl2N3O/c29-25-8-5-9-26(27(25)30)33-16-14-32(15-17-33)13-4-3-12-31-28(34)21-10-11-24-22(19-21)18-20-6-1-2-7-23(20)24/h1-2,5-11,19H,12-18H2,(H,31,34) KHRMKRBHPQLYHH-UHFFFAOYSA-N 50129437 9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-ynyl}-amide::CHEMBL71364 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129437&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309603 104021020 CHEMBL71364 ZINC13534425 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235492 Clc1cccc(N2CCN(CCCNC(=O)c3cccc4Cc5ccccc5-c34)CC2)c1Cl InChI=1S/C27H27Cl2N3O/c28-23-10-4-11-24(26(23)29)32-16-14-31(15-17-32)13-5-12-30-27(33)22-9-3-7-20-18-19-6-1-2-8-21(19)25(20)22/h1-4,6-11H,5,12-18H2,(H,30,33) XFOUSEPBBUXFFN-UHFFFAOYSA-N 50129440 9H-Fluorene-4-carboxylic acid {3-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL69718 D(2) dopamine receptor Rattus norvegicus 376 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309524 104021023 CHEMBL69718 ZINC13534356 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235493 Clc1cccc(N2CCN(CCCCNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl InChI=1S/C28H29Cl2N3O/c29-25-8-5-9-26(27(25)30)33-16-14-32(15-17-33)13-4-3-12-31-28(34)21-10-11-24-22(19-21)18-20-6-1-2-7-23(20)24/h1-2,5-11,19H,3-4,12-18H2,(H,31,34) YJPWVCIGSHWNON-UHFFFAOYSA-N 50071959 9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL300780::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide D(2) dopamine receptor Rattus norvegicus 911 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9891901 103965649 CHEMBL300780 6674 ZINC01545255 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235494 Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(cc3)-c3ccccn3)CC2)c1Cl InChI=1S/C26H28Cl2N4O/c27-22-6-5-8-24(25(22)28)32-18-16-31(17-19-32)15-4-3-14-30-26(33)21-11-9-20(10-12-21)23-7-1-2-13-29-23/h1-2,5-13H,3-4,14-19H2,(H,30,33) YJGPWNCHDJDGJR-UHFFFAOYSA-N 50129426 CHEMBL69451::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-4-(pyridin-2-yl)benzamide::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-4-pyridin-2-yl-benzamide D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129426&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9826580 104021009 CHEMBL69451 6675 ZINC13534388 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235498 Clc1cccc(N2CCN(CCCNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl InChI=1S/C27H27Cl2N3O/c28-24-7-3-8-25(26(24)29)32-15-13-31(14-16-32)12-4-11-30-27(33)20-9-10-23-21(18-20)17-19-5-1-2-6-22(19)23/h1-3,5-10,18H,4,11-17H2,(H,30,33) WPLCSVMMEFEPPZ-UHFFFAOYSA-N 50104124 9H-Fluorene-2-carboxylic acid {3-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL67750 D(2) dopamine receptor Rattus norvegicus 396 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104124&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10972865 104000107 CHEMBL67750 ZINC13534360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235500 Clc1cccc(N2CCN(CCCCNC(=O)c3cccc4C(=O)c5ccccc5-c34)CC2)c1Cl InChI=1S/C28H27Cl2N3O2/c29-23-11-6-12-24(26(23)30)33-17-15-32(16-18-33)14-4-3-13-31-28(35)22-10-5-9-21-25(22)19-7-1-2-8-20(19)27(21)34/h1-2,5-12H,3-4,13-18H2,(H,31,35) WOWYFQWPMWYJNL-UHFFFAOYSA-N 50104122 9-Oxo-9H-fluorene-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL301242 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104122&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10436285 104000105 CHEMBL301242 ZINC13534346 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50235502 Clc1cccc(N2CCN(C\C=C/CNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl InChI=1S/C28H27Cl2N3O/c29-25-8-5-9-26(27(25)30)33-16-14-32(15-17-33)13-4-3-12-31-28(34)21-10-11-24-22(19-21)18-20-6-1-2-7-23(20)24/h1-11,19H,12-18H2,(H,31,34)/b4-3- ZCTVOGWWMHRQLN-ARJAWSKDSA-N 50129436 9H-Fluorene-2-carboxylic acid {(Z)-4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide::CHEMBL304766 D(2) dopamine receptor Rattus norvegicus 87 ChEMBL 10.1016/s0960-894x(03)00389-5 10.7270/Q21Z43SN 12798330 Newman, AH; Cao, J; Bennett, CJ; Robarge, MJ; Freeman, RA; Luedtke, RR National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309773 104021019 CHEMBL304766 ZINC13534406 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50229298 O=C1CN(CN2CCN(CC2)c2cccc3ccccc23)C(=O)C2CCCN12 InChI=1S/C22H26N4O2/c27-21-15-25(22(28)20-9-4-10-26(20)21)16-23-11-13-24(14-12-23)19-8-3-6-17-5-1-2-7-18(17)19/h1-3,5-8,20H,4,9-16H2 CTZWGZSINBFHFD-UHFFFAOYSA-N 50126475 2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione::CHEMBL285066 D(2) dopamine receptor Rattus norvegicus 192 ChEMBL 10.1016/s0960-894x(03)00160-4 10.7270/Q2BV7FZX 12668005 Lopez-Rodriguez, ML; Morcillo, MJ; Fernandez, E; Benhamu, B; Tejada, I; Ayala, D; Viso, A; Olivella, M; Pardo, L; Delgado, M; Manzanares, J; Fuentes, JA Universidad Complutense http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126475&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10317515 104018551 CHEMBL285066 ZINC28475410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50243376 CCCN(CCC)C1CCC2=C(CCCC2C1)N=O InChI=1S/C16H28N2O/c1-3-10-18(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)17-19/h13-14H,3-12H2,1-2H3 SZWSFWTZDMZIJS-UHFFFAOYSA-N 50133184 6-Dipropylamino-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one oxime::CHEMBL132575 D(2) dopamine receptor Rattus norvegicus 2234 ChEMBL 10.1021/jm0307786 10.7270/Q2M61JP7 12954065 Venhuis, BJ; Dijkstra, D; Wustrow, D; Meltzer, LT; Wise, LD; Johnson, SJ; Wikstrom, HV University Center for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133184&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91932639 104024112 CHEMBL132575 ZINC13527257 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50243378 CCCN(CCC)C1CCC2=C(CCC\C2=N/OC)C1 InChI=1S/C17H30N2O/c1-4-11-19(12-5-2)15-9-10-16-14(13-15)7-6-8-17(16)18-20-3/h15H,4-13H2,1-3H3/b18-17+ PQHRVMZXOMRVOE-ISLYRVAYSA-N 50133185 6-Dipropylamino-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one O-methyl-oxime::CHEMBL130398 D(2) dopamine receptor Rattus norvegicus 2295 ChEMBL 10.1021/jm0307786 10.7270/Q2M61JP7 12954065 Venhuis, BJ; Dijkstra, D; Wustrow, D; Meltzer, LT; Wise, LD; Johnson, SJ; Wikstrom, HV University Center for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133185&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10221294 104024113 CHEMBL130398 ZINC13527261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50243380 CCCN(CCC)c1ccc2CCCCc2c1 InChI=1S/C16H25N/c1-3-11-17(12-4-2)16-10-9-14-7-5-6-8-15(14)13-16/h9-10,13H,3-8,11-12H2,1-2H3 NIAGNBAOEWXBKS-UHFFFAOYSA-N 50133186 CHEMBL132626::Dipropyl-(5,6,7,8-tetrahydro-naphthalen-2-yl)-amine::N,N-dipropyl-N-5,6,7,8-tetrahydronaphthalen-2-ylamine D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm0307786 10.7270/Q2M61JP7 12954065 Venhuis, BJ; Dijkstra, D; Wustrow, D; Meltzer, LT; Wise, LD; Johnson, SJ; Wikstrom, HV University Center for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133186 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133186&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44354072 104024114 CHEMBL132626 ZINC27408780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50243381 CCCN(CCC)C1CCc2c(C1)ccc(O)c2O InChI=1S/C16H25NO2/c1-3-9-17(10-4-2)13-6-7-14-12(11-13)5-8-15(18)16(14)19/h5,8,13,18-19H,3-4,6-7,9-11H2,1-2H3 JQHSYAQISCFWOK-UHFFFAOYSA-N 50026553 (+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::(+/-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::(-)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene-1,2-diol (DP-5,6-ADTN)::CHEMBL11845 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm0307786 10.7270/Q2M61JP7 12954065 Venhuis, BJ; Dijkstra, D; Wustrow, D; Meltzer, LT; Wise, LD; Johnson, SJ; Wikstrom, HV University Center for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026553&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122167 103936193 CHEMBL11845 ZINC05833076 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252257 COc1cc2CCN(CCNC(=O)c3cc(Br)cc(OC)c3OC)Cc2cc1OC InChI=1S/C22H27BrN2O5/c1-27-18-9-14-5-7-25(13-15(14)10-19(18)28-2)8-6-24-22(26)17-11-16(23)12-20(29-3)21(17)30-4/h9-12H,5-8,13H2,1-4H3,(H,24,26) GSHZYENJHIPEJJ-UHFFFAOYSA-N 50137615 5-Bromo-N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-2,3-dimethoxy-benzamide::CHEMBL64176 D(2) dopamine receptor Rattus norvegicus 714.0 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137615&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11488451 104027758 CHEMBL64176 ZINC13588502 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252259 COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCc2ccccc2C1 InChI=1S/C23H23BrN2O2/c1-28-22-19-9-5-4-8-18(19)21(24)14-20(22)23(27)25-11-13-26-12-10-16-6-2-3-7-17(16)15-26/h2-9,14H,10-13,15H2,1H3,(H,25,27) LQOYFQQIZFEVDY-UHFFFAOYSA-N 50137616 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2-(3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-amide::CHEMBL60133 D(2) dopamine receptor Rattus norvegicus 132 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137616&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11235994 104027759 CHEMBL60133 ZINC13588498 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252271 COc1cc2CCN(CCNC(=O)c3cc(Br)c4ccccc4c3OC)Cc2cc1OC InChI=1S/C25H27BrN2O4/c1-30-22-12-16-8-10-28(15-17(16)13-23(22)31-2)11-9-27-25(29)20-14-21(26)18-6-4-5-7-19(18)24(20)32-3/h4-7,12-14H,8-11,15H2,1-3H3,(H,27,29) NJTZXTZDMKNNIW-UHFFFAOYSA-N 50137622 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-amide::CHEMBL60140 D(2) dopamine receptor Rattus norvegicus 241 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137622&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11317999 104027765 CHEMBL60140 ZINC13588499 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252272 Clc1cccc(N2CCN(CCCCNC(=O)c3cccc4C(=O)c5ccccc5-c34)CC2)c1Cl InChI=1S/C28H27Cl2N3O2/c29-23-11-6-12-24(26(23)30)33-17-15-32(16-18-33)14-4-3-13-31-28(35)22-10-5-9-21-25(22)19-7-1-2-8-20(19)27(21)34/h1-2,5-12H,3-4,13-18H2,(H,31,35) WOWYFQWPMWYJNL-UHFFFAOYSA-N 50104122 9-Oxo-9H-fluorene-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL301242 D(2) dopamine receptor Rattus norvegicus 89 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104122&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10436285 104000105 CHEMBL301242 ZINC13534346 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252275 COc1cc2CCN(CCCCNC(=O)c3cc(Br)c4ccccc4c3OC)Cc2cc1OC InChI=1S/C27H31BrN2O4/c1-32-24-14-18-10-13-30(17-19(18)15-25(24)33-2)12-7-6-11-29-27(31)22-16-23(28)20-8-4-5-9-21(20)26(22)34-3/h4-5,8-9,14-16H,6-7,10-13,17H2,1-3H3,(H,29,31) XXDKXXVEKGJMFE-UHFFFAOYSA-N 50137623 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-butyl]-amide::CHEMBL60139 D(2) dopamine receptor Rattus norvegicus 741 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137623&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11191741 104027766 CHEMBL60139 ZINC13588500 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252276 COc1cc2CCN(CCCCNC(=O)c3cc(Br)cc(OC)c3OC)Cc2cc1OC InChI=1S/C24H31BrN2O5/c1-29-20-11-16-7-10-27(15-17(16)12-21(20)30-2)9-6-5-8-26-24(28)19-13-18(25)14-22(31-3)23(19)32-4/h11-14H,5-10,15H2,1-4H3,(H,26,28) UNYNHWPKQAKANT-UHFFFAOYSA-N 50137618 5-Bromo-N-[4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-butyl]-2,3-dimethoxy-benzamide::5-bromo-N-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-2,3-dimethoxybenzamide::CHEMBL291439 D(2) dopamine receptor Rattus norvegicus 2200 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10458892 104027761 CHEMBL291439 ZINC13588503 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252277 COc1cc(Br)cc(-c2ccc(CN3CCc4ccccc4C3)[nH]2)c1OC InChI=1S/C22H23BrN2O2/c1-26-21-12-17(23)11-19(22(21)27-2)20-8-7-18(24-20)14-25-10-9-15-5-3-4-6-16(15)13-25/h3-8,11-12,24H,9-10,13-14H2,1-2H3 WZKNBWSCKIWALS-UHFFFAOYSA-N 50137627 2-[5-(5-Bromo-2,3-dimethoxy-phenyl)-1H-pyrrol-2-ylmethyl]-1,2,3,4-tetrahydro-isoquinoline::CHEMBL303796 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137627&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44303759 104027770 CHEMBL303796 ZINC13476302 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252279 COc1cc2CCN(CCNC(=O)c3cc(Br)ccc3OC)Cc2cc1OC InChI=1S/C21H25BrN2O4/c1-26-18-5-4-16(22)12-17(18)21(25)23-7-9-24-8-6-14-10-19(27-2)20(28-3)11-15(14)13-24/h4-5,10-12H,6-9,13H2,1-3H3,(H,23,25) KSANSFZVRVSECI-UHFFFAOYSA-N 50137624 5-Bromo-N-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-2-methoxy-benzamide::CHEMBL64261 D(2) dopamine receptor Rattus norvegicus 3570 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137624&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25184808 104027767 CHEMBL64261 ZINC13588505 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252281 COc1ccc(Br)cc1C(=O)NCCN1CCc2ccccc2C1 InChI=1S/C19H21BrN2O2/c1-24-18-7-6-16(20)12-17(18)19(23)21-9-11-22-10-8-14-4-2-3-5-15(14)13-22/h2-7,12H,8-11,13H2,1H3,(H,21,23) XLWBMMOOMNHHBQ-UHFFFAOYSA-N 50137619 5-Bromo-N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-2-methoxy-benzamide::CHEMBL64751 D(2) dopamine receptor Rattus norvegicus 2190 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137619&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11315257 104027762 CHEMBL64751 ZINC13588504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252282 Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(cc3)-c3ccccc3)CC2)c1Cl InChI=1S/C27H29Cl2N3O/c28-24-9-6-10-25(26(24)29)32-19-17-31(18-20-32)16-5-4-15-30-27(33)23-13-11-22(12-14-23)21-7-2-1-3-8-21/h1-3,6-14H,4-5,15-20H2,(H,30,33) JNGNQZWCWJWYDP-UHFFFAOYSA-N 50122056 Biphenyl-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL305362 D(2) dopamine receptor Rattus norvegicus 262 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122056&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11016342 104014769 CHEMBL305362 ZINC13492667 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252283 Clc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4s3)CC2)c1Cl InChI=1S/C23H25Cl2N3OS/c24-18-7-5-8-19(22(18)25)28-14-12-27(13-15-28)11-4-3-10-26-23(29)21-16-17-6-1-2-9-20(17)30-21/h1-2,5-9,16H,3-4,10-15H2,(H,26,29) CPTSTFKVXWZGEV-UHFFFAOYSA-N 50119390 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL59725::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide D(2) dopamine receptor Rattus norvegicus 3600 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119390&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10276451 104012608 CHEMBL59725 ZINC13491634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252285 COc1ccc(C)cc1C(=O)NCCCCN1CCc2cc(OC)c(OC)cc2C1 InChI=1S/C24H32N2O4/c1-17-7-8-21(28-2)20(13-17)24(27)25-10-5-6-11-26-12-9-18-14-22(29-3)23(30-4)15-19(18)16-26/h7-8,13-15H,5-6,9-12,16H2,1-4H3,(H,25,27) KOEMMHBJOHMMBF-UHFFFAOYSA-N 50137628 CHEMBL1830682::CHEMBL60048::N-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-2-methoxy-5-methylbenzamide::N-[4-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-butyl]-2-methoxy-5-methyl-benzamide::[3H]-N-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-2-methoxy-5-methylbenzamide D(2) dopamine receptor Rattus norvegicus 642 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137628&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11165837 104027771 CHEMBL1830682CHEMBL60048 ZINC13588507 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252289 COc1cc2CCN(Cc3ccc([nH]3)-c3cc(Br)cc(OC)c3OC)Cc2cc1OC InChI=1S/C24H27BrN2O4/c1-28-21-9-15-7-8-27(13-16(15)10-22(21)29-2)14-18-5-6-20(26-18)19-11-17(25)12-23(30-3)24(19)31-4/h5-6,9-12,26H,7-8,13-14H2,1-4H3 NSOZZCMSSAVDQC-UHFFFAOYSA-N 50137620 2-[5-(5-Bromo-2,3-dimethoxy-phenyl)-1H-pyrrol-2-ylmethyl]-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline::CHEMBL60213 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137620&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44303796 104027763 CHEMBL60213 ZINC13476304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252291 COc1cc(Br)cc(C(=O)NCCCCN2CCN(CC2)c2cccc(Cl)c2Cl)c1OC InChI=1S/C23H28BrCl2N3O3/c1-31-20-15-16(24)14-17(22(20)32-2)23(30)27-8-3-4-9-28-10-12-29(13-11-28)19-7-5-6-18(25)21(19)26/h5-7,14-15H,3-4,8-13H2,1-2H3,(H,27,30) RYXXRKZWJMNUEJ-UHFFFAOYSA-N 50137626 5-Bromo-N-{4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-2,3-dimethoxy-benzamide::CHEMBL59713 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137626&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10392655 104027769 CHEMBL59713 ZINC26162325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252293 COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C24H24BrCl2N3O2/c1-32-23-17-6-3-2-5-16(17)19(25)15-18(23)24(31)28-9-10-29-11-13-30(14-12-29)21-8-4-7-20(26)22(21)27/h2-8,15H,9-14H2,1H3,(H,28,31) RAZKAAYRLZXGBT-UHFFFAOYSA-N 50071960 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL287198 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9828632 103965650 CHEMBL287198 ZINC53084591 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252296 COc1c(cc(Br)c2ccccc12)C(=O)NC1CCN(C1)C1C2CC3CC(C2)CC1C3 InChI=1S/C26H31BrN2O2/c1-31-25-21-5-3-2-4-20(21)23(27)13-22(25)26(30)28-19-6-7-29(14-19)24-17-9-15-8-16(11-17)12-18(24)10-15/h2-5,13,15-19,24H,6-12,14H2,1H3,(H,28,30) XLNJGZHDQBCQJA-UHFFFAOYSA-N 50137621 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-adamantan-2-yl-pyrrolidin-3-yl)-amide::CHEMBL62638 D(2) dopamine receptor Rattus norvegicus 5.8 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137621&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44303758 104027764 CHEMBL62638 ZINC13862871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252300 COc1cc(Br)cc(C(=O)NCCN2CCc3ccccc3C2)c1OC InChI=1S/C20H23BrN2O3/c1-25-18-12-16(21)11-17(19(18)26-2)20(24)22-8-10-23-9-7-14-5-3-4-6-15(14)13-23/h3-6,11-12H,7-10,13H2,1-2H3,(H,22,24) PWXJESIQWPYCPX-UHFFFAOYSA-N 50137625 5-Bromo-N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-2,3-dimethoxy-benzamide::CHEMBL305366 D(2) dopamine receptor Rattus norvegicus 430 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137625&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11304676 104027768 CHEMBL305366 ZINC13588501 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252306 COc1cc2CCN(CCNC(=O)c3cc(C)ccc3OC)Cc2cc1OC InChI=1S/C22H28N2O4/c1-15-5-6-19(26-2)18(11-15)22(25)23-8-10-24-9-7-16-12-20(27-3)21(28-4)13-17(16)14-24/h5-6,11-13H,7-10,14H2,1-4H3,(H,23,25) CKJPETQDQGIHJS-UHFFFAOYSA-N 50137617 CHEMBL64260::N-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-2-methoxy-5-methyl-benzamide D(2) dopamine receptor Rattus norvegicus 2850 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11338096 104027760 CHEMBL64260 ZINC13588506 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252308 Clc1cccc(N2CCN(CCCCNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl InChI=1S/C28H29Cl2N3O/c29-25-8-5-9-26(27(25)30)33-16-14-32(15-17-33)13-4-3-12-31-28(34)21-10-11-24-22(19-21)18-20-6-1-2-7-23(20)24/h1-2,5-11,19H,3-4,12-18H2,(H,31,34) YJPWVCIGSHWNON-UHFFFAOYSA-N 50071959 9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL300780::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide D(2) dopamine receptor Rattus norvegicus 217 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9891901 103965649 CHEMBL300780 6674 ZINC01545255 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252309 COc1c(cc(Br)c2ccccc12)C(=O)NCCCCN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C26H28BrCl2N3O2/c1-34-25-19-8-3-2-7-18(19)21(27)17-20(25)26(33)30-11-4-5-12-31-13-15-32(16-14-31)23-10-6-9-22(28)24(23)29/h2-3,6-10,17H,4-5,11-16H2,1H3,(H,30,33) LGTFCCLATINIEE-UHFFFAOYSA-N 50122031 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL61789 D(2) dopamine receptor Rattus norvegicus 107 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11028157 104014744 CHEMBL61789 ZINC26173028 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50252315 COc1c(cc(Br)c2ccccc12)C(=O)NC[C@H]1CCCN1C1CCCCC1 InChI=1S/C23H29BrN2O2/c1-28-22-19-12-6-5-11-18(19)21(24)14-20(22)23(27)25-15-17-10-7-13-26(17)16-8-3-2-4-9-16/h5-6,11-12,14,16-17H,2-4,7-10,13,15H2,1H3,(H,25,27)/t17-/m1/s1 JVVXYJOBIBKLSD-QGZVFWFLSA-N 50099815 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid ((R)-1-cyclohexyl-pyrrolidin-2-ylmethyl)-amide::4-Bromo-1-methoxy-naphthalene-2-carboxylic acid (1-cyclohexyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL53038 D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1016/j.bmcl.2003.09.083 10.7270/Q2CV4H45 14684327 Mach, RH; Huang, Y; Freeman, RA; Wu, L; Vangveravong, S; Luedtke, RR Wake Forest University School of Medicine http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599447 103996640 CHEMBL53038 ZINC13862882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50246942 CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(Br)c1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(19)7-6-11(16)14(13)21-2/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 QRMZHEDLUQMLGK-JTQLQIEISA-N 50026561 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::CHEMBL23519 D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1016/j.bmcl.2003.08.063 10.7270/Q27M07BC 14592497 Baldwin, RM; Fu, X; Kula, NS; Baldessarini, RJ; Amici, L; Innis, RB; Tamagnan, GD Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493823 103936201 CHEMBL23519 ZINC05851784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50246943 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1016/j.bmcl.2003.08.063 10.7270/Q27M07BC 14592497 Baldwin, RM; Fu, X; Kula, NS; Baldessarini, RJ; Amici, L; Innis, RB; Tamagnan, GD Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50246946 CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)ccc1OC InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 CANPFCFJURGKAX-JTQLQIEISA-N 50012961 (-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::CHEMBL267723::N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide (IBZM)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide( (S)-(-)IBZM) D(2) dopamine receptor Rattus norvegicus 1.7 ChEMBL 10.1016/j.bmcl.2003.08.063 10.7270/Q27M07BC 14592497 Baldwin, RM; Fu, X; Kula, NS; Baldessarini, RJ; Amici, L; Innis, RB; Tamagnan, GD Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 107995 103925209 CHEMBL267723 ZINC03786360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50246949 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 7.2 ChEMBL 10.1016/j.bmcl.2003.08.063 10.7270/Q27M07BC 14592497 Baldwin, RM; Fu, X; Kula, NS; Baldessarini, RJ; Amici, L; Innis, RB; Tamagnan, GD Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50246951 CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(I)c1OC InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(19)7-6-11(16)14(13)21-2/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 FKOZYIIIHDNKFQ-JTQLQIEISA-N 50135412 CHEMBL423331::N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-3-iodo-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 196 ChEMBL 10.1016/j.bmcl.2003.08.063 10.7270/Q27M07BC 14592497 Baldwin, RM; Fu, X; Kula, NS; Baldessarini, RJ; Amici, L; Innis, RB; Tamagnan, GD Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50135412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50135412&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14691952 104025780 CHEMBL423331 ZINC12356025 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50246952 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.075000 ChEMBL 10.1016/j.bmcl.2003.08.063 10.7270/Q27M07BC 14592497 Baldwin, RM; Fu, X; Kula, NS; Baldessarini, RJ; Amici, L; Innis, RB; Tamagnan, GD Yale University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250501 Cn1c2ncn(CCCCN3CCc4ccccc4C3)c2c(=O)n(C)c1=O InChI=1S/C20H25N5O2.ClH/c1-22-18-17(19(26)23(2)20(22)27)25(14-21-18)11-6-5-10-24-12-9-15-7-3-4-8-16(15)13-24;/h3-4,7-8,14H,5-6,9-13H2,1-2H3;1H NPMOVNCZMGTWMN-UHFFFAOYSA-N 50034801 CHEMBL3361003 D(2) dopamine receptor Rattus norvegicus 7823 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987649 313066526 CHEMBL3361003 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250502 Cn1c2ncn(CCCN3CCc4ccccc4C3)c2c(=O)n(C)c1=O InChI=1S/C19H23N5O2.ClH/c1-21-17-16(18(25)22(2)19(21)26)24(13-20-17)10-5-9-23-11-8-14-6-3-4-7-15(14)12-23;/h3-4,6-7,13H,5,8-12H2,1-2H3;1H NTIGOHIOIBVJJX-UHFFFAOYSA-N 50034800 CHEMBL3361002 D(2) dopamine receptor Rattus norvegicus 2705 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987648 313066525 CHEMBL3361002 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250503 Cn1c2ncn(CCCCCN3CCN(CC3)c3cccc(Cl)c3)c2c(=O)n(C)c1=O InChI=1S/C22H29ClN6O2.ClH/c1-25-20-19(21(30)26(2)22(25)31)29(16-24-20)10-5-3-4-9-27-11-13-28(14-12-27)18-8-6-7-17(23)15-18;/h6-8,15-16H,3-5,9-14H2,1-2H3;1H JXBBTIRIOXBXLF-UHFFFAOYSA-N 50034799 CHEMBL3361001 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987647 313066524 CHEMBL3361001 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250504 COc1ccccc1N1CCN(CCCCCn2cnc3n(C)c(=O)n(C)c(=O)c23)CC1 InChI=1S/C23H32N6O3.ClH/c1-25-21-20(22(30)26(2)23(25)31)29(17-24-21)12-8-4-7-11-27-13-15-28(16-14-27)18-9-5-6-10-19(18)32-3;/h5-6,9-10,17H,4,7-8,11-16H2,1-3H3;1H YMJMBHOKHYLUDZ-UHFFFAOYSA-N 50034797 CHEMBL3361000 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987646 313066523 CHEMBL3361000 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250505 Cn1c2ncn(CCCCCN3CCN(CC3)c3ccccc3)c2c(=O)n(C)c1=O InChI=1S/C22H30N6O2.ClH/c1-24-20-19(21(29)25(2)22(24)30)28(17-23-20)12-8-4-7-11-26-13-15-27(16-14-26)18-9-5-3-6-10-18;/h3,5-6,9-10,17H,4,7-8,11-16H2,1-2H3;1H XFSRNEHJWUOLTP-UHFFFAOYSA-N 50034796 CHEMBL3360999 D(2) dopamine receptor Rattus norvegicus 356 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118724639 312528627 CHEMBL3360999 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250506 Cn1c2ncn(CCCCN3CCN(CC3)c3ccc(Cl)c(Cl)c3)c2c(=O)n(C)c1=O InChI=1S/C21H26Cl2N6O2.ClH/c1-25-19-18(20(30)26(2)21(25)31)29(14-24-19)8-4-3-7-27-9-11-28(12-10-27)15-5-6-16(22)17(23)13-15;/h5-6,13-14H,3-4,7-12H2,1-2H3;1H ZJMJCFGXMWADSK-UHFFFAOYSA-N 50034795 CHEMBL3360998 D(2) dopamine receptor Rattus norvegicus 73 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034795&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987645 313066522 CHEMBL3360998 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250507 Cn1c2ncn(CCCCN3CCN(CC3)c3cccc(Cl)c3Cl)c2c(=O)n(C)c1=O InChI=1S/C21H26Cl2N6O2.ClH/c1-25-19-18(20(30)26(2)21(25)31)29(14-24-19)9-4-3-8-27-10-12-28(13-11-27)16-7-5-6-15(22)17(16)23;/h5-7,14H,3-4,8-13H2,1-2H3;1H UUZXMGXKPBNTBD-UHFFFAOYSA-N 50034794 CHEMBL3360997 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034794&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987644 313066521 CHEMBL3360997 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250508 Cn1c2ncn(CCCCN3CCN(CC3)c3cccc(Cl)c3)c2c(=O)n(C)c1=O InChI=1S/C21H27ClN6O2.ClH/c1-24-19-18(20(29)25(2)21(24)30)28(15-23-19)9-4-3-8-26-10-12-27(13-11-26)17-7-5-6-16(22)14-17;/h5-7,14-15H,3-4,8-13H2,1-2H3;1H CIYYZIMGBLFERV-UHFFFAOYSA-N 50034793 CHEMBL3360996 D(2) dopamine receptor Rattus norvegicus 195 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034793&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987643 313066520 CHEMBL3360996 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250509 COc1ccccc1N1CCN(CCCCn2cnc3n(C)c(=O)n(C)c(=O)c23)CC1 InChI=1S/C22H30N6O3.ClH/c1-24-20-19(21(29)25(2)22(24)30)28(16-23-20)11-7-6-10-26-12-14-27(15-13-26)17-8-4-5-9-18(17)31-3;/h4-5,8-9,16H,6-7,10-15H2,1-3H3;1H ATMOXDFJUIWWDB-UHFFFAOYSA-N 50034792 CHEMBL3360995 D(2) dopamine receptor Rattus norvegicus 65 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987642 313066519 CHEMBL3360995 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250510 Cn1c2ncn(CCCCN3CCN(CC3)c3ccccc3)c2c(=O)n(C)c1=O InChI=1S/C21H28N6O2.ClH/c1-23-19-18(20(28)24(2)21(23)29)27(16-22-19)11-7-6-10-25-12-14-26(15-13-25)17-8-4-3-5-9-17;/h3-5,8-9,16H,6-7,10-15H2,1-2H3;1H VYJLWTSKBVYVBN-UHFFFAOYSA-N 50034807 CHEMBL3360994 D(2) dopamine receptor Rattus norvegicus 1006 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987655 313066532 CHEMBL3360994 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250511 Cn1c2ncn(CCCN3CCN(CC3)c3cccc(Cl)c3)c2c(=O)n(C)c1=O InChI=1S/C20H25ClN6O2.ClH/c1-23-18-17(19(28)24(2)20(23)29)27(14-22-18)8-4-7-25-9-11-26(12-10-25)16-6-3-5-15(21)13-16;/h3,5-6,13-14H,4,7-12H2,1-2H3;1H TUMJQIMKVJQZQY-UHFFFAOYSA-N 50034806 CHEMBL3360993 D(2) dopamine receptor Rattus norvegicus 3187 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987654 313066531 CHEMBL3360993 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250512 COc1ccccc1N1CCN(CCCn2cnc3n(C)c(=O)n(C)c(=O)c23)CC1 InChI=1S/C21H28N6O3.ClH/c1-23-19-18(20(28)24(2)21(23)29)27(15-22-19)10-6-9-25-11-13-26(14-12-25)16-7-4-5-8-17(16)30-3;/h4-5,7-8,15H,6,9-14H2,1-3H3;1H XXLGFBATEKMROI-UHFFFAOYSA-N 50034805 CHEMBL3360992 D(2) dopamine receptor Rattus norvegicus 944 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987653 313066530 CHEMBL3360992 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250513 Cn1c2ncn(CCCN3CCN(CC3)c3ccccc3)c2c(=O)n(C)c1=O InChI=1S/C20H26N6O2.ClH/c1-22-18-17(19(27)23(2)20(22)28)26(15-21-18)10-6-9-24-11-13-25(14-12-24)16-7-4-3-5-8-16;/h3-5,7-8,15H,6,9-14H2,1-2H3;1H VVFCOTSQNBOXPP-UHFFFAOYSA-N 50034804 CHEMBL3360991 D(2) dopamine receptor Rattus norvegicus 1088 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034804&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987652 313066529 CHEMBL3360991 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250547 Cn1c2ncn(CCCCCN3CCc4ccccc4C3)c2c(=O)n(C)c1=O InChI=1S/C21H27N5O2.ClH/c1-23-19-18(20(27)24(2)21(23)28)26(15-22-19)12-7-3-6-11-25-13-10-16-8-4-5-9-17(16)14-25;/h4-5,8-9,15H,3,6-7,10-14H2,1-2H3;1H PHWRDQGHKXBPLO-UHFFFAOYSA-N 50034802 CHEMBL3361004 D(2) dopamine receptor Rattus norvegicus 1222 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118987650 313066527 CHEMBL3361004 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50250548 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 7.0 ChEMBL 10.1016/j.bmc.2014.11.008 10.7270/Q2WD425D 25435254 Partyka, A; Chlon-Rzepa, G; Wasik, A; Jastrzebska-Wiesek, M; Bucki, A; Kolaczkowski, M; Satala, G; Bojarski, AJ; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056595 Fc1ccc2c(CCCCN3C4CCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 InChI=1S/C24H23F2N3O/c25-14-5-8-19-18(11-14)24-21(27-19)13-16-6-9-22(24)29(16)10-2-1-3-20-17-7-4-15(26)12-23(17)30-28-20/h4-5,7-8,11-12,16,22,27H,1-3,6,9-10,13H2 RKKLLFDATFBVDR-UHFFFAOYSA-N 50036649 (7R,10S)-1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::(7S,10R)-1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::CHEMBL284163 D(2) dopamine receptor Rattus norvegicus 2380 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646191 103944290 CHEMBL284163 ZINC13827354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50275258 Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCOc4c3)c2c1 InChI=1S/C23H26FN3O2/c24-18-4-6-21-20(13-18)17(15-25-21)3-1-2-8-26-9-11-27(12-10-26)19-5-7-22-23(14-19)29-16-28-22/h4-7,13-15,25H,1-3,8-12,16H2 AMIPACMJPDEFPD-UHFFFAOYSA-N 50152002 3-[4-(4-Benzo[1,3]dioxol-5-yl-piperazin-1-yl)-butyl]-5-fluoro-1H-indole::CHEMBL188798 D(2) dopamine receptor Rattus norvegicus <100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152002&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11293380 104040136 CHEMBL188798 ZINC13582481 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50275259 N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3c(cccc3C#N)C#N)c2c1 InChI=1S/C25H24N6/c26-15-19-7-8-24-23(14-19)22(18-29-24)4-1-2-9-30-10-12-31(13-11-30)25-20(16-27)5-3-6-21(25)17-28/h3,5-8,14,18,29H,1-2,4,9-13H2 NGKGVCSPLNBGIR-UHFFFAOYSA-N 50152016 2-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-isophthalonitrile::CHEMBL189869 D(2) dopamine receptor Rattus norvegicus <100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152016&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11442169 104040150 CHEMBL189869 ZINC13582509 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50275260 N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCCc4c3)c2c1 InChI=1S/C26H30N4O/c27-18-20-6-8-25-24(16-20)22(19-28-25)4-1-2-10-29-11-13-30(14-12-29)23-7-9-26-21(17-23)5-3-15-31-26/h6-9,16-17,19,28H,1-5,10-15H2 HVDRFZFBSWKCCX-UHFFFAOYSA-N 50152003 3-[4-(4-Chroman-6-yl-piperazin-1-yl)-butyl]-1H-indole-5-carbonitrile::CHEMBL188481 D(2) dopamine receptor Rattus norvegicus <42 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152003&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11774334 104040137 CHEMBL188481 ZINC13582536 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50275261 COC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C26H31N3O4/c1-31-26(30)19-5-7-23-22(16-19)20(18-27-23)4-2-3-9-28-10-12-29(13-11-28)21-6-8-24-25(17-21)33-15-14-32-24/h5-8,16-18,27H,2-4,9-15H2,1H3 MDHVRPTXQRFWPA-UHFFFAOYSA-N 50152018 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid methyl ester::CHEMBL188848 D(2) dopamine receptor Rattus norvegicus <100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152018&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11168397 104040152 CHEMBL188848 ZINC13582473 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50275264 O=Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C25H29N3O3/c29-18-19-4-6-23-22(15-19)20(17-26-23)3-1-2-8-27-9-11-28(12-10-27)21-5-7-24-25(16-21)31-14-13-30-24/h4-7,15-18,26H,1-3,8-14H2 QJAPFMHRCXYIEW-UHFFFAOYSA-N 50152007 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carbaldehyde::CHEMBL185768 D(2) dopamine receptor Rattus norvegicus <100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152007&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11350652 104040141 CHEMBL185768 ZINC13582466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50276383 Fc1ccc2n(C3CCN(CCN4CCCc5ccccc5C4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C24H27FN4O2/c25-18-7-8-22-21(16-18)26-24(31)29(22)19-9-12-27(13-10-19)14-15-28-11-3-5-17-4-1-2-6-20(17)23(28)30/h1-2,4,6-8,16,19H,3,5,9-15H2,(H,26,31) KOTITFQGTVUMBT-UHFFFAOYSA-N 50125260 2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-ethyl}-2,3,4,5-tetrahydro-benzo[c]azepin-1-one::CHEMBL273921 D(2) dopamine receptor Rattus norvegicus 234 ChEMBL 10.1021/jm0498102 10.7270/Q2FQ9W2Z 15267230 Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50125260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50125260&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9888494 104017488 CHEMBL273921 ZINC01489492 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50276385 CCCN(CCC)[C@H]1CCc2c(C1)cccc2-c1c(OC)cccc1OC InChI=1S/C24H33NO2/c1-5-15-25(16-6-2)19-13-14-20-18(17-19)9-7-10-21(20)24-22(26-3)11-8-12-23(24)27-4/h7-12,19H,5-6,13-17H2,1-4H3/t19-/m0/s1 UZMHRPBLJWVAII-IBGZPJMESA-N 50150674 CHEMBL361875::[(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dipropyl-amine D(2) dopamine receptor Rattus norvegicus 1210 ChEMBL 10.1021/jm0498102 10.7270/Q2FQ9W2Z 15267230 Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150674&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10429067 104039033 CHEMBL361875 ZINC13581251 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50276387 CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1ccccc1 InChI=1S/C21H27NO/c1-3-13-22(14-4-2)19-15-18-11-8-12-20(21(18)23-16-19)17-9-6-5-7-10-17/h5-12,19H,3-4,13-16H2,1-2H3/t19-/m1/s1 OYEKUFKQGCYWCG-LJQANCHMSA-N 50150676 ((R)-8-Phenyl-chroman-3-yl)-dipropyl-amine::(R)-8-phenyl-N,N-dipropylchroman-3-amine::CHEMBL186112 D(2) dopamine receptor Rattus norvegicus 106 ChEMBL 10.1021/jm0498102 10.7270/Q2FQ9W2Z 15267230 Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150676&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11267988 104039035 CHEMBL186112 ZINC13581257 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50276411 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2C#N)c-31 InChI=1S/C25H22N2/c1-16-6-3-9-19(15-26)23(16)20-10-5-8-18-14-22-25-17(12-13-27(22)2)7-4-11-21(25)24(18)20/h3-11,22H,12-14H2,1-2H3/t22-/m1/s1 APEZAWGOFKUHCA-JOCHJYFZSA-N 50098549 (6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::(6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::3-Methyl-2-((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::CHEMBL28056 D(2) dopamine receptor Rattus norvegicus 498.0 ChEMBL 10.1021/jm0498102 10.7270/Q2FQ9W2Z 15267230 Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11725453 103995562 CHEMBL28056 ZINC01493886 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50276415 CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1ccccc1OC InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)18-15-17-9-8-11-20(22(17)25-16-18)19-10-6-7-12-21(19)24-3/h6-12,18H,4-5,13-16H2,1-3H3/t18-/m1/s1 VDFXNGPWAIBQSN-GOSISDBHSA-N 50150679 CHEMBL186316::[(R)-8-(2-Methoxy-phenyl)-chroman-3-yl]-dipropyl-amine D(2) dopamine receptor Rattus norvegicus 512.0 ChEMBL 10.1021/jm0498102 10.7270/Q2FQ9W2Z 15267230 Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11772153 104039038 CHEMBL186316 ZINC13581259 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50276421 COc1cccc(OC)c1-c1cccc2C[C@H](CCc12)N(C)C InChI=1S/C20H25NO2/c1-21(2)15-11-12-16-14(13-15)7-5-8-17(16)20-18(22-3)9-6-10-19(20)23-4/h5-10,15H,11-13H2,1-4H3/t15-/m0/s1 BFHVQDBLFZYJPG-HNNXBMFYSA-N 50150673 CHEMBL363466::[(S)-5-(2,6-Dimethoxy-phenyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 241 ChEMBL 10.1021/jm0498102 10.7270/Q2FQ9W2Z 15267230 Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150673&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10064052 104039032 CHEMBL363466 ZINC13581255 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50276432 CCCN(CCC)[C@@H]1COc2c(C1)cccc2-c1ccccc1OC InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)18-15-17-9-8-11-20(22(17)25-16-18)19-10-6-7-12-21(19)24-3/h6-12,18H,4-5,13-16H2,1-3H3/t18-/m0/s1 VDFXNGPWAIBQSN-SFHVURJKSA-N 50150683 CHEMBL361287::[(S)-8-(2-Methoxy-phenyl)-chroman-3-yl]-dipropyl-amine D(2) dopamine receptor Rattus norvegicus 2110 ChEMBL 10.1021/jm0498102 10.7270/Q2FQ9W2Z 15267230 Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150683&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11209976 104039042 CHEMBL361287 ZINC13581261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50276433 CCCN(CCC)[C@H]1COc2c(C1)cccc2-c1ccc(OC)cc1 InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)19-15-18-7-6-8-21(22(18)25-16-19)17-9-11-20(24-3)12-10-17/h6-12,19H,4-5,13-16H2,1-3H3/t19-/m1/s1 QWKYFMXJKILTAJ-LJQANCHMSA-N 50150678 CHEMBL186758::[(R)-8-(4-Methoxy-phenyl)-chroman-3-yl]-dipropyl-amine D(2) dopamine receptor Rattus norvegicus 741 ChEMBL 10.1021/jm0498102 10.7270/Q2FQ9W2Z 15267230 Holmberg, P; Sohn, D; Leideborg, R; Caldirola, P; Zlatoidsky, P; Hanson, S; Mohell, N; Rosqvist, S; Nordvall, G; Johansson, AM; Johansson, R Uppsala University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150678&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11151958 104039037 CHEMBL186758 ZINC13581263 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50266539 COc1cccc2C(CCN3CCN(CC3)C3CCCCC3)CCCc12 InChI=1S/C23H36N2O/c1-26-23-12-6-10-21-19(7-5-11-22(21)23)13-14-24-15-17-25(18-16-24)20-8-3-2-4-9-20/h6,10,12,19-20H,2-5,7-9,11,13-18H2,1H3 SYWSXXBZIRUBHU-UHFFFAOYSA-N 50145013 1-Cyclohexyl-4-[2-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-ethyl]-piperazine::CHEMBL74858 D(2) dopamine receptor Rattus norvegicus 1620 ChEMBL 10.1021/jm031026e 10.7270/Q2DN44HS 15084129 Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145013&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11405620 104033941 CHEMBL74858 ZINC22931085 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50266540 COc1cccc2C(CN3CCN(CC3)C3CCCCC3)CCCc12 InChI=1S/C22H34N2O/c1-25-22-12-6-10-20-18(7-5-11-21(20)22)17-23-13-15-24(16-14-23)19-8-3-2-4-9-19/h6,10,12,18-19H,2-5,7-9,11,13-17H2,1H3 YHVGSPGZCCLSHP-UHFFFAOYSA-N 50145014 1-Cyclohexyl-4-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-piperazine::CHEMBL75878 D(2) dopamine receptor Rattus norvegicus 4260.0 ChEMBL 10.1021/jm031026e 10.7270/Q2DN44HS 15084129 Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145014&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11439301 104033942 CHEMBL75878 ZINC22778605 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50266548 COc1cccc2C(CCCCCCN3CCN(CC3)C3CCCCC3)CCCc12 InChI=1S/C27H44N2O/c1-30-27-17-10-15-25-23(12-9-16-26(25)27)11-5-2-3-8-18-28-19-21-29(22-20-28)24-13-6-4-7-14-24/h10,15,17,23-24H,2-9,11-14,16,18-22H2,1H3 YWDVQCRTJZURGA-UHFFFAOYSA-N 50145023 1-Cyclohexyl-4-[6-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-hexyl]-piperazine::CHEMBL74811 D(2) dopamine receptor Rattus norvegicus 3480 ChEMBL 10.1021/jm031026e 10.7270/Q2DN44HS 15084129 Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145023&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11281378 104033951 CHEMBL74811 ZINC22931135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50266553 COc1ccc2CCCC(CCCN3CCN(CC3)C3CCCCC3)c2c1 InChI=1S/C24H38N2O/c1-27-23-13-12-21-8-5-7-20(24(21)19-23)9-6-14-25-15-17-26(18-16-25)22-10-3-2-4-11-22/h12-13,19-20,22H,2-11,14-18H2,1H3 TUMKKQCFMIMRJN-UHFFFAOYSA-N 50145025 1-Cyclohexyl-4-[3-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL75444 D(2) dopamine receptor Rattus norvegicus 479 ChEMBL 10.1021/jm031026e 10.7270/Q2DN44HS 15084129 Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145025&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44314013 104033953 CHEMBL75444 ZINC22931106 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50266560 COc1cccc2C(CCCCCN3CCN(CC3)C3CCCCC3)CCCc12 InChI=1S/C26H42N2O/c1-29-26-16-9-14-24-22(11-8-15-25(24)26)10-4-3-7-17-27-18-20-28(21-19-27)23-12-5-2-6-13-23/h9,14,16,22-23H,2-8,10-13,15,17-21H2,1H3 YTACRVLZUUYUQX-UHFFFAOYSA-N 50145027 1-Cyclohexyl-4-[5-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-pentyl]-piperazine::CHEMBL306365 D(2) dopamine receptor Rattus norvegicus 2450 ChEMBL 10.1021/jm031026e 10.7270/Q2DN44HS 15084129 Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11292472 104033955 CHEMBL306365 ZINC22931129 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50266565 COc1cccc2C(CCCCN3CCN(CC3)C3CCCCC3)CCCc12 InChI=1S/C25H40N2O/c1-28-25-15-8-13-23-21(10-7-14-24(23)25)9-5-6-16-26-17-19-27(20-18-26)22-11-3-2-4-12-22/h8,13,15,21-22H,2-7,9-12,14,16-20H2,1H3 XYLRIJUMSWFUTA-UHFFFAOYSA-N 50145028 1-Cyclohexyl-4-[4-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperazine::1-cyclohexyl-4-(4-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)butyl)piperazine::CHEMBL77220 D(2) dopamine receptor Rattus norvegicus 3670 ChEMBL 10.1021/jm031026e 10.7270/Q2DN44HS 15084129 Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11199981 104033956 CHEMBL77220 ZINC22931117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50266566 COc1cccc2C(CCCN3CCN(CC3)C3CCCCC3)CCCc12 InChI=1S/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3 PHRCDWVPTULQMT-UHFFFAOYSA-N 50048866 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperazine::1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)propyl]piperazine::1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine::CHEMBL53325::PB-28 D(2) dopamine receptor Rattus norvegicus 604 ChEMBL 10.1021/jm031026e 10.7270/Q2DN44HS 15084129 Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search YT1 7M93 10474335 103979247 CHEMBL53325 6681 ZINC22931097 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50266583 COc1cccc2C(CCCc12)N1CCN(CC1)C1CCCCC1 InChI=1S/C21H32N2O/c1-24-21-12-6-9-18-19(21)10-5-11-20(18)23-15-13-22(14-16-23)17-7-3-2-4-8-17/h6,9,12,17,20H,2-5,7-8,10-11,13-16H2,1H3 ZKMTXBPXPWCYGI-UHFFFAOYSA-N 50145018 1-Cyclohexyl-4-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-piperazine::CHEMBL309064 D(2) dopamine receptor Rattus norvegicus 1160 ChEMBL 10.1021/jm031026e 10.7270/Q2DN44HS 15084129 Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V Università di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145018&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11381875 104033946 CHEMBL309064 ZINC22931079 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279235 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC)c(OC)c3)c2c1 InChI=1S/C25H33N3O3/c1-29-21-8-9-23-22(17-21)19(18-26-23)6-4-5-11-27-12-14-28(15-13-27)20-7-10-24(30-2)25(16-20)31-3/h7-10,16-18,26H,4-6,11-15H2,1-3H3 RMQSZNRXFGKRBN-UHFFFAOYSA-N 50151931 3-{4-[4-(3,4-Dimethoxy-phenyl)-piperazin-1-yl]-butyl}-5-methoxy-1H-indole::CHEMBL186409 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151931&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396440 104040065 CHEMBL186409 ZINC13582401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279236 NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C23H28N4O/c24-23(28)18-9-10-22-21(16-18)19(17-25-22)6-4-5-11-26-12-14-27(15-13-26)20-7-2-1-3-8-20/h1-3,7-10,16-17,25H,4-6,11-15H2,(H2,24,28) RAUAAMMVLJHXCC-UHFFFAOYSA-N 50151932 3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indole-5-carboxylic acid amide::CHEMBL365716 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151932&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11303411 104040066 CHEMBL365716 ZINC13582373 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279238 COc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccc(OC)cc23)CC1 InChI=1S/C25H30N2O2/c1-28-22-8-6-19(7-9-22)20-12-15-27(16-13-20)14-4-3-5-21-18-26-25-11-10-23(29-2)17-24(21)25/h6-12,17-18,26H,3-5,13-16H2,1-2H3 CIRIBUYXUVMNIM-UHFFFAOYSA-N 50151934 5-Methoxy-3-{4-[4-(4-methoxy-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL366104 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151934&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396409 104040068 CHEMBL366104 ZINC13582355 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279246 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(NC(C)=O)cc3)c2c1 InChI=1S/C25H32N4O2/c1-19(30)27-21-6-8-22(9-7-21)29-15-13-28(14-16-29)12-4-3-5-20-18-26-25-11-10-23(31-2)17-24(20)25/h6-11,17-18,26H,3-5,12-16H2,1-2H3,(H,27,30) BXMULCSTOJNWHO-UHFFFAOYSA-N 50151939 CHEMBL364150::N-(4-{4-[4-(5-Methoxy-1H-indol-3-yl)-butyl]-piperazin-1-yl}-phenyl)-acetamide D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396365 104040073 CHEMBL364150 ZINC13582392 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279247 CCOc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC)cc3)c2c1 InChI=1S/C25H33N3O2/c1-3-30-23-11-12-25-24(18-23)20(19-26-25)6-4-5-13-27-14-16-28(17-15-27)21-7-9-22(29-2)10-8-21/h7-12,18-19,26H,3-6,13-17H2,1-2H3 GPUAJZMBIFTLOG-UHFFFAOYSA-N 50151942 5-Ethoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL185779 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396425 104040076 CHEMBL185779 ZINC13582413 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279248 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OCc4ccccc4)cc3)c2c1 InChI=1S/C30H35N3O2/c1-34-28-14-15-30-29(21-28)25(22-31-30)9-5-6-16-32-17-19-33(20-18-32)26-10-12-27(13-11-26)35-23-24-7-3-2-4-8-24/h2-4,7-8,10-15,21-22,31H,5-6,9,16-20,23H2,1H3 AQLHFZXPURDXGQ-UHFFFAOYSA-N 50151941 3-{4-[4-(4-Benzyloxy-phenyl)-piperazin-1-yl]-butyl}-5-methoxy-1H-indole::CHEMBL188408 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396449 104040075 CHEMBL188408 ZINC13582383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279257 COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OCc4ccccc4)cc23)CC1 InChI=1S/C30H35N3O2/c1-34-27-12-10-26(11-13-27)33-19-17-32(18-20-33)16-6-5-9-25-22-31-30-15-14-28(21-29(25)30)35-23-24-7-3-2-4-8-24/h2-4,7-8,10-15,21-22,31H,5-6,9,16-20,23H2,1H3 MSSOSZCLQHFAJP-UHFFFAOYSA-N 50151947 5-Benzyloxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL186415 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396560 104040081 CHEMBL186415 ZINC13582421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279261 NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3C(N)=O)c2c1 InChI=1S/C24H29N5O2/c25-23(30)17-8-9-21-20(15-17)18(16-27-21)5-3-4-10-28-11-13-29(14-12-28)22-7-2-1-6-19(22)24(26)31/h1-2,6-9,15-16,27H,3-5,10-14H2,(H2,25,30)(H2,26,31) GMWUCQTVJHIJAK-UHFFFAOYSA-N 50151950 3-{4-[4-(2-Carbamoyl-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL186608 D(2) dopamine receptor Rattus norvegicus 97 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11384601 104040084 CHEMBL186608 ZINC13582448 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279264 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCCc4c3)c2c1 InChI=1S/C26H33N3O2/c1-30-23-8-9-25-24(18-23)21(19-27-25)5-2-3-11-28-12-14-29(15-13-28)22-7-10-26-20(17-22)6-4-16-31-26/h7-10,17-19,27H,2-6,11-16H2,1H3 KFNBERZIJGZUQL-UHFFFAOYSA-N 50151951 3-[4-(4-Chroman-6-yl-piperazin-1-yl)-butyl]-5-methoxy-1H-indole::CHEMBL359793 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151951&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19438846 104040085 CHEMBL359793 ZINC01542115 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279265 COC(=O)c1ccc2[nH]cc(CCCCN3CCC(CC3)c3ccccc3)c2c1 InChI=1S/C25H30N2O2/c1-29-25(28)21-10-11-24-23(17-21)22(18-26-24)9-5-6-14-27-15-12-20(13-16-27)19-7-3-2-4-8-19/h2-4,7-8,10-11,17-18,20,26H,5-6,9,12-16H2,1H3 ATHPTSAHKOYGIM-UHFFFAOYSA-N 50151949 3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole-5-carboxylic acid methyl ester::CHEMBL186034 D(2) dopamine receptor Rattus norvegicus 113 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151949&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12137276 104040083 CHEMBL186034 ZINC13582365 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279267 CCOc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC)cc23)CC1 InChI=1S/C25H33N3O2/c1-3-30-22-9-7-21(8-10-22)28-16-14-27(15-17-28)13-5-4-6-20-19-26-25-12-11-23(29-2)18-24(20)25/h7-12,18-19,26H,3-6,13-17H2,1-2H3 PBXLRHIKMFGPMT-UHFFFAOYSA-N 50151953 3-{4-[4-(4-Ethoxy-phenyl)-piperazin-1-yl]-butyl}-5-methoxy-1H-indole::CHEMBL188471 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151953&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396468 104040087 CHEMBL188471 ZINC13582380 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279269 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(O)cc3)c2c1 InChI=1S/C23H29N3O2/c1-28-21-9-10-23-22(16-21)18(17-24-23)4-2-3-11-25-12-14-26(15-13-25)19-5-7-20(27)8-6-19/h5-10,16-17,24,27H,2-4,11-15H2,1H3 QZPJXIWUORTZLP-UHFFFAOYSA-N 50151955 4-{4-[4-(5-Methoxy-1H-indol-3-yl)-butyl]-piperazin-1-yl}-phenol::CHEMBL186173 D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396429 104040089 CHEMBL186173 ZINC13582378 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279272 COC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C24H29N3O2/c1-29-24(28)19-10-11-23-22(17-19)20(18-25-23)7-5-6-12-26-13-15-27(16-14-26)21-8-3-2-4-9-21/h2-4,8-11,17-18,25H,5-7,12-16H2,1H3 GTCRIIOPGCGQMP-UHFFFAOYSA-N 50151959 3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indole-5-carboxylic acid methyl ester::CHEMBL188183 D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19936446 104040093 CHEMBL188183 ZINC13582367 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279277 COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C24H28N2O/c1-27-22-10-11-24-23(17-22)21(18-25-24)9-5-6-14-26-15-12-20(13-16-26)19-7-3-2-4-8-19/h2-4,7-8,10-12,17-18,25H,5-6,9,13-16H2,1H3 OUSYTGMUXWLOBH-UHFFFAOYSA-N 50002177 5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::5-methoxy-3-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-1H-indole::CHEMBL130327 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10408477 103916483 CHEMBL130327 ZINC13582350 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279281 OC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C23H27N3O2/c27-23(28)18-9-10-22-21(16-18)19(17-24-22)6-4-5-11-25-12-14-26(15-13-25)20-7-2-1-3-8-20/h1-3,7-10,16-17,24H,4-6,11-15H2,(H,27,28) XWAGQFOILGMJLI-UHFFFAOYSA-N 50151963 3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indole-5-carboxylic acid::CHEMBL365433 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151963&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11280358 104040097 CHEMBL365433 ZINC13582369 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279290 NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(O)cc3)c2c1 InChI=1S/C23H28N4O2/c24-23(29)17-4-9-22-21(15-17)18(16-25-22)3-1-2-10-26-11-13-27(14-12-26)19-5-7-20(28)8-6-19/h4-9,15-16,25,28H,1-3,10-14H2,(H2,24,29) VXYWRBIWAVBFCQ-UHFFFAOYSA-N 50151966 3-{4-[4-(4-Hydroxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL439664 D(2) dopamine receptor Rattus norvegicus 156 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11429291 104040100 CHEMBL439664 ZINC13582430 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279294 CC(=O)Nc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C(N)=O)CC1 InChI=1S/C25H31N5O2/c1-18(31)28-21-6-8-22(9-7-21)30-14-12-29(13-15-30)11-3-2-4-20-17-27-24-10-5-19(25(26)32)16-23(20)24/h5-10,16-17,27H,2-4,11-15H2,1H3,(H2,26,32)(H,28,31) YAHUFCAARVRTSU-UHFFFAOYSA-N 50151954 3-{4-[4-(4-Acetylamino-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL189708 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11259059 104040088 CHEMBL189708 ZINC13582450 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279296 NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C25H30N4O3/c26-25(30)18-4-6-22-21(15-18)19(17-27-22)3-1-2-8-28-9-11-29(12-10-28)20-5-7-23-24(16-20)32-14-13-31-23/h4-7,15-17,27H,1-3,8-14H2,(H2,26,30) JVGGPWIASBTPGW-UHFFFAOYSA-N 50151948 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL364592 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11154775 104040082 CHEMBL364592 ZINC13582443 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279297 COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C(N)=O)CC1 InChI=1S/C24H30N4O2/c1-30-21-8-6-20(7-9-21)28-14-12-27(13-15-28)11-3-2-4-19-17-26-23-10-5-18(24(25)29)16-22(19)23/h5-10,16-17,26H,2-4,11-15H2,1H3,(H2,25,29) QTDOPNDTFBPKHU-UHFFFAOYSA-N 50151946 3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL360419 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9978693 104040080 CHEMBL360419 ZINC03986678 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279299 Oc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C22H27N3O/c26-20-9-10-22-21(16-20)18(17-23-22)6-4-5-11-24-12-14-25(15-13-24)19-7-2-1-3-8-19/h1-3,7-10,16-17,23,26H,4-6,11-15H2 HUPROOXJTZKFAQ-UHFFFAOYSA-N 50151960 3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indol-5-ol::CHEMBL362771 D(2) dopamine receptor Rattus norvegicus 4.2 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396416 104040094 CHEMBL362771 ZINC13582362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279300 OC(=O)c1ccc2[nH]cc(CCCCN3CCC(CC3)c3ccccc3)c2c1 InChI=1S/C24H28N2O2/c27-24(28)20-9-10-23-22(16-20)21(17-25-23)8-4-5-13-26-14-11-19(12-15-26)18-6-2-1-3-7-18/h1-3,6-7,9-10,16-17,19,25H,4-5,8,11-15H2,(H,27,28) UTBJLSMZCXDLAF-UHFFFAOYSA-N 50151965 3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole-5-carboxylic acid::CHEMBL188184 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151965&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11326368 104040099 CHEMBL188184 ZINC12356250 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279302 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C25H31N3O3/c1-29-21-6-7-23-22(17-21)19(18-26-23)4-2-3-9-27-10-12-28(13-11-27)20-5-8-24-25(16-20)31-15-14-30-24/h5-8,16-18,26H,2-4,9-15H2,1H3 VLOAJINDPKHKIO-UHFFFAOYSA-N 50151952 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-5-methoxy-1H-indole::CHEMBL188296 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11154398 104040086 CHEMBL188296 ZINC13582406 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279303 COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC4CCCC4)cc23)CC1 InChI=1S/C28H37N3O2/c1-32-24-11-9-23(10-12-24)31-18-16-30(17-19-31)15-5-4-6-22-21-29-28-14-13-26(20-27(22)28)33-25-7-2-3-8-25/h9-14,20-21,25,29H,2-8,15-19H2,1H3 GOHAIWYNEPLTLZ-UHFFFAOYSA-N 50151967 5-Cyclopentyloxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL364341 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396486 104040101 CHEMBL364341 ZINC13582418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279304 NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3C#N)c2c1 InChI=1S/C24H27N5O/c25-16-19-5-1-2-7-23(19)29-13-11-28(12-14-29)10-4-3-6-20-17-27-22-9-8-18(24(26)30)15-21(20)22/h1-2,5,7-9,15,17,27H,3-4,6,10-14H2,(H2,26,30) HJQVFWPFCDCXRG-UHFFFAOYSA-N 50151933 3-{4-[4-(2-Cyano-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL189450 D(2) dopamine receptor Rattus norvegicus 6.2 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151933&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11452383 104040067 CHEMBL189450 ZINC13582453 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279306 NC(=O)c1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C(N)=O)CC1 InChI=1S/C24H29N5O2/c25-23(30)17-4-7-20(8-5-17)29-13-11-28(12-14-29)10-2-1-3-19-16-27-22-9-6-18(24(26)31)15-21(19)22/h4-9,15-16,27H,1-3,10-14H2,(H2,25,30)(H2,26,31) TYPRYKUBSLGLEL-UHFFFAOYSA-N 50151945 3-{4-[4-(4-Carbamoyl-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL185938 D(2) dopamine receptor Rattus norvegicus >850 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11774457 104040079 CHEMBL185938 ZINC13582445 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279309 COc1c(Cl)cc(cc1Cl)N1CCN(CCCCc2c[nH]c3ccc(cc23)C(N)=O)CC1 InChI=1S/C24H28Cl2N4O2/c1-32-23-20(25)13-18(14-21(23)26)30-10-8-29(9-11-30)7-3-2-4-17-15-28-22-6-5-16(24(27)31)12-19(17)22/h5-6,12-15,28H,2-4,7-11H2,1H3,(H2,27,31) LIIZQDKCZCZHLB-UHFFFAOYSA-N 50151973 3-{4-[4-(3,5-Dichloro-4-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL366269 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151973&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11167431 104040107 CHEMBL366269 ZINC13582432 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279310 O=C1N(CCCCN2CCN(CC2)c2ncccn2)S(=O)(=O)c2ccccc12 InChI=1S/C19H23N5O3S/c25-18-16-6-1-2-7-17(16)28(26,27)24(18)11-4-3-10-22-12-14-23(15-13-22)19-20-8-5-9-21-19/h1-2,5-9H,3-4,10-15H2 TZJUVVIWVWFLCD-UHFFFAOYSA-N 50005127 1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one::1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one (Ipsapirone)::1,1-Dioxo-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one(Ipsapirone)::CHEMBL8412::IPSAPIRONE D(2) dopamine receptor Rattus norvegicus 2900 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005127&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56971 103918673 CHEMBL8412 42 ZINC01999529 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279312 CCCCCOc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC)cc3)c2c1 InChI=1S/C28H39N3O2/c1-3-4-7-20-33-26-13-14-28-27(21-26)23(22-29-28)8-5-6-15-30-16-18-31(19-17-30)24-9-11-25(32-2)12-10-24/h9-14,21-22,29H,3-8,15-20H2,1-2H3 WQLVHDHVUFPOBT-UHFFFAOYSA-N 50151968 3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-5-pentyloxy-1H-indole::CHEMBL434899 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151968&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396552 104040102 CHEMBL434899 ZINC13582416 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279314 NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCCc4c3)c2c1 InChI=1S/C26H32N4O2/c27-26(31)20-6-8-24-23(17-20)21(18-28-24)4-1-2-10-29-11-13-30(14-12-29)22-7-9-25-19(16-22)5-3-15-32-25/h6-9,16-18,28H,1-5,10-15H2,(H2,27,31) ZOTMPHLOFULIPB-UHFFFAOYSA-N 50151971 3-[4-(4-Chroman-6-yl-piperazin-1-yl)-butyl]-1H-indole-5-carboxylic acid amide::CHEMBL185915 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151971&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10410574 104040105 CHEMBL185915 ZINC03986680 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279317 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCc4c3)c2c1 InChI=1S/C25H31N3O2/c1-29-22-6-7-24-23(17-22)20(18-26-24)4-2-3-10-27-11-13-28(14-12-27)21-5-8-25-19(16-21)9-15-30-25/h5-8,16-18,26H,2-4,9-15H2,1H3 FBORTSDQSNZPLD-UHFFFAOYSA-N 50151962 3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-yl]-butyl}-5-methoxy-1H-indole::CHEMBL189454 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151962&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12137277 104040096 CHEMBL189454 ZINC13582399 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279318 COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC(C)=O)cc23)CC1 InChI=1S/C25H31N3O3/c1-19(29)31-23-10-11-25-24(17-23)20(18-26-25)5-3-4-12-27-13-15-28(16-14-27)21-6-8-22(30-2)9-7-21/h6-11,17-18,26H,3-5,12-16H2,1-2H3 SPDSMYRGVAEZCP-UHFFFAOYSA-N 50151943 Acetic acid 3-{4-[4-(4-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indol-5-yl ester::CHEMBL186115 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151943&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11486994 104040077 CHEMBL186115 ZINC13582425 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279320 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC(C)=O)cc3)c2c1 InChI=1S/C25H31N3O3/c1-19(29)31-22-8-6-21(7-9-22)28-15-13-27(14-16-28)12-4-3-5-20-18-26-25-11-10-23(30-2)17-24(20)25/h6-11,17-18,26H,3-5,12-16H2,1-2H3 FCBAMQJWCNMMEU-UHFFFAOYSA-N 50151972 Acetic acid 4-{4-[4-(5-methoxy-1H-indol-3-yl)-butyl]-piperazin-1-yl}-phenyl ester::CHEMBL185899 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151972&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396358 104040106 CHEMBL185899 ZINC13582389 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279323 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C23H29N3O/c1-27-21-10-11-23-22(17-21)19(18-24-23)7-5-6-12-25-13-15-26(16-14-25)20-8-3-2-4-9-20/h2-4,8-11,17-18,24H,5-7,12-16H2,1H3 BKPFUMLELZUBFG-UHFFFAOYSA-N 50151956 5-Methoxy-3-[4-(4-phenyl-piperazin-1-yl)-butyl]-1H-indole::CHEMBL186229 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396457 104040090 CHEMBL186229 ZINC13582376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279326 COc1ccc(N2CCN(CCCCc3c[nH]c4ccc(cc34)C(N)=O)CC2)c(OC)c1 InChI=1S/C25H32N4O3/c1-31-20-7-9-23(24(16-20)32-2)29-13-11-28(12-14-29)10-4-3-5-19-17-27-22-8-6-18(25(26)30)15-21(19)22/h6-9,15-17,27H,3-5,10-14H2,1-2H3,(H2,26,30) BACQGYHNOMRIBQ-UHFFFAOYSA-N 50151976 3-{4-[4-(2,4-Dimethoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL364181 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151976&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11476079 104040110 CHEMBL364181 ZINC13582441 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279328 NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3cccc(F)c3C#N)c2c1 InChI=1S/C24H26FN5O/c25-21-5-3-6-23(20(21)15-26)30-12-10-29(11-13-30)9-2-1-4-18-16-28-22-8-7-17(24(27)31)14-19(18)22/h3,5-8,14,16,28H,1-2,4,9-13H2,(H2,27,31) NCDKJAFICFICEX-UHFFFAOYSA-N 50151969 3-{4-[4-(2-Cyano-3-fluoro-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL186423 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151969&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11177596 104040103 CHEMBL186423 ZINC13582456 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279329 COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(OC)cc23)CC1 InChI=1S/C24H31N3O2/c1-28-21-8-6-20(7-9-21)27-15-13-26(14-16-27)12-4-3-5-19-18-25-24-11-10-22(29-2)17-23(19)24/h6-11,17-18,25H,3-5,12-16H2,1-2H3 MOFQVDOYTSRLKU-UHFFFAOYSA-N 50151935 5-Methoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL187196 D(2) dopamine receptor Rattus norvegicus 420 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151935&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9800737 104040069 CHEMBL187196 ZINC02010334 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279330 Oc1ccc2[nH]cc(CCCCN3CCC(CC3)c3ccccc3)c2c1 InChI=1S/C23H28N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-10,16-17,19,24,26H,4-5,8,11-15H2 DOWRAWDUVGYWFP-UHFFFAOYSA-N 50151964 3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indol-5-ol::CHEMBL363932 D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396396 104040098 CHEMBL363932 ZINC13582360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279331 COC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(OC)cc3)c2c1 InChI=1S/C25H31N3O3/c1-30-22-9-7-21(8-10-22)28-15-13-27(14-16-28)12-4-3-5-20-18-26-24-11-6-19(17-23(20)24)25(29)31-2/h6-11,17-18,26H,3-5,12-16H2,1-2H3 LIPBRTUWGKEQNE-UHFFFAOYSA-N 50151974 3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid methyl ester::CHEMBL360415 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151974&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11247206 104040108 CHEMBL360415 ZINC13582427 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279332 NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCOc4c3)c2c1 InChI=1S/C24H28N4O3/c25-24(29)17-4-6-21-20(13-17)18(15-26-21)3-1-2-8-27-9-11-28(12-10-27)19-5-7-22-23(14-19)31-16-30-22/h4-7,13-15,26H,1-3,8-12,16H2,(H2,25,29) CINVAGCQZHMSDL-UHFFFAOYSA-N 50151930 3-[4-(4-Benzo[1,3]dioxol-5-yl-piperazin-1-yl)-butyl]-1H-indole-5-carboxylic acid amide::CHEMBL363537 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9823464 104040064 CHEMBL363537 ZINC01540000 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279336 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3cc(C)c(OC)c(C)c3)c2c1 InChI=1S/C26H35N3O2/c1-19-15-22(16-20(2)26(19)31-4)29-13-11-28(12-14-29)10-6-5-7-21-18-27-25-9-8-23(30-3)17-24(21)25/h8-9,15-18,27H,5-7,10-14H2,1-4H3 WRIJSTMOEVEIIV-UHFFFAOYSA-N 50151977 5-Methoxy-3-{4-[4-(4-methoxy-3,5-dimethyl-phenyl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL426616 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151977&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396561 104040111 CHEMBL426616 ZINC13582397 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279340 COc1ccccc1N1CCN(CCCCc2c[nH]c3ccc(cc23)C(N)=O)CC1 InChI=1S/C24H30N4O2/c1-30-23-8-3-2-7-22(23)28-14-12-27(13-15-28)11-5-4-6-19-17-26-21-10-9-18(24(25)29)16-20(19)21/h2-3,7-10,16-17,26H,4-6,11-15H2,1H3,(H2,25,29) DCVFPUZNCLIHIT-UHFFFAOYSA-N 50151937 3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL185860 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151937&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11165673 104040071 CHEMBL185860 ZINC13582435 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279342 COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccc4OCOc4c3)c2c1 InChI=1S/C25H28N2O3/c1-28-21-6-7-23-22(15-21)20(16-26-23)4-2-3-11-27-12-9-18(10-13-27)19-5-8-24-25(14-19)30-17-29-24/h5-9,14-16,26H,2-4,10-13,17H2,1H3 UNWPOGGIFDUAHY-UHFFFAOYSA-N 50151957 3-[4-(4-Benzo[1,3]dioxol-5-yl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-5-methoxy-1H-indole::CHEMBL186814 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396410 104040091 CHEMBL186814 ZINC28390852 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279343 NC(=O)c1ccc2[nH]cc(CCCCN3CCC(CC3)c3ccccc3)c2c1 InChI=1S/C24H29N3O/c25-24(28)20-9-10-23-22(16-20)21(17-26-23)8-4-5-13-27-14-11-19(12-15-27)18-6-2-1-3-7-18/h1-3,6-7,9-10,16-17,19,26H,4-5,8,11-15H2,(H2,25,28) RBDWWKPSSYIBCB-UHFFFAOYSA-N 50151978 3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole-5-carboxylic acid amide::CHEMBL188625 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151978&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11291810 104040112 CHEMBL188625 ZINC13582371 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279346 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCOc4c3)c2c1 InChI=1S/C24H29N3O3/c1-28-20-6-7-22-21(15-20)18(16-25-22)4-2-3-9-26-10-12-27(13-11-26)19-5-8-23-24(14-19)30-17-29-23/h5-8,14-16,25H,2-4,9-13,17H2,1H3 ZLYNSXAUXWPSCC-UHFFFAOYSA-N 50151961 3-[4-(4-Benzo[1,3]dioxol-5-yl-piperazin-1-yl)-butyl]-5-methoxy-1H-indole::CHEMBL366271 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396446 104040095 CHEMBL366271 ZINC13582404 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279347 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3cc(OC)c(OC)c(OC)c3)c2c1 InChI=1S/C26H35N3O4/c1-30-21-8-9-23-22(17-21)19(18-27-23)7-5-6-10-28-11-13-29(14-12-28)20-15-24(31-2)26(33-4)25(16-20)32-3/h8-9,15-18,27H,5-7,10-14H2,1-4H3 CGBJTVRUDYBOKU-UHFFFAOYSA-N 50151936 5-Methoxy-3-{4-[4-(3,4,5-trimethoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL188674 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151936&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44396483 104040070 CHEMBL188674 ZINC13582410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279351 NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCc4c3)c2c1 InChI=1S/C25H30N4O2/c26-25(30)19-4-6-23-22(16-19)20(17-27-23)3-1-2-9-28-10-12-29(13-11-28)21-5-7-24-18(15-21)8-14-31-24/h4-7,15-17,27H,1-3,8-14H2,(H2,26,30) UMXKZXWFCNSZOX-UHFFFAOYSA-N 50151958 3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL363292 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11750460 104040092 CHEMBL363292 ZINC13582438 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279352 Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 HGEYJZMMUGWEOT-UHFFFAOYSA-N 50002173 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole D(2) dopamine receptor Rattus norvegicus 5.6 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 219050 103916479 48558 CHEMBL431367 52 ZINC01548439 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279357 CCOCCOCCOc1cccc(N2CCN(CCCCc3c[nH]c4ccc(cc34)C(N)=O)CC2)c1C#N InChI=1S/C30H39N5O4/c1-2-37-16-17-38-18-19-39-29-8-5-7-28(26(29)21-31)35-14-12-34(13-15-35)11-4-3-6-24-22-33-27-10-9-23(30(32)36)20-25(24)27/h5,7-10,20,22,33H,2-4,6,11-19H2,1H3,(H2,32,36) ZSUFDIUGZONWRS-UHFFFAOYSA-N 50151940 3-[4-(4-{2-Cyano-3-[2-(2-ethoxy-ethoxy)-ethoxy]-phenyl}-piperazin-1-yl)-butyl]-1H-indole-5-carboxylic acid amide::CHEMBL360179 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm040792y 10.7270/Q28S4PCR 15341483 Heinrich, T; Bottcher, H; Bartoszyk, GD; Greiner, HE; Seyfried, CA; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151940&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11785924 104040074 CHEMBL360179 ZINC13582458 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279360 O=c1ccc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C26H26N4O2/c27-17-19-4-7-24-23(15-19)21(18-28-24)3-1-2-10-29-11-13-30(14-12-29)22-6-8-25-20(16-22)5-9-26(31)32-25/h4-9,15-16,18,28H,1-3,10-14H2 JYRQRDDPHJEJCJ-UHFFFAOYSA-N 50151983 3-{4-[4-(2-Oxo-2H-chromen-6-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL189704 D(2) dopamine receptor Rattus norvegicus 740 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151983&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9867165 104040117 CHEMBL189704 ZINC01546681 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279365 N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4[nH]ccc4c3)c2c1 InChI=1S/C25H27N5/c26-17-19-4-6-25-23(15-19)21(18-28-25)3-1-2-10-29-11-13-30(14-12-29)22-5-7-24-20(16-22)8-9-27-24/h4-9,15-16,18,27-28H,1-3,10-14H2 BIHUQIVPVHHXCO-UHFFFAOYSA-N 50151981 3-{4-[4-(1H-Indol-5-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL189759 D(2) dopamine receptor Rattus norvegicus 5.7 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151981&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11213557 104040115 CHEMBL189759 ZINC13582544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279371 N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3cccc4nsnc34)c2c1 InChI=1S/C23H24N6S/c24-15-17-7-8-20-19(14-17)18(16-25-20)4-1-2-9-28-10-12-29(13-11-28)22-6-3-5-21-23(22)27-30-26-21/h3,5-8,14,16,25H,1-2,4,9-13H2 WNFZGOUONAMKNP-UHFFFAOYSA-N 50151989 3-[4-(4-Benzo[1,2,5]thiadiazol-4-yl-piperazin-1-yl)-butyl]-1H-indole-5-carbonitrile::CHEMBL359566 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151989&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11775354 104040123 CHEMBL359566 ZINC13582542 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279374 CCOCCOCCOc1cccc(N2CCN(CCCCc3c[nH]c4ccc(cc34)C#N)CC2)c1C#N InChI=1S/C30H37N5O3/c1-2-36-16-17-37-18-19-38-30-8-5-7-29(27(30)22-32)35-14-12-34(13-15-35)11-4-3-6-25-23-33-28-10-9-24(21-31)20-26(25)28/h5,7-10,20,23,33H,2-4,6,11-19H2,1H3 KAWWVHKWESRAHV-UHFFFAOYSA-N 50151990 3-[4-(4-{2-Cyano-3-[2-(2-ethoxy-ethoxy)-ethoxy]-phenyl}-piperazin-1-yl)-butyl]-1H-indole-5-carbonitrile::CHEMBL186468 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151990&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11375756 104040124 CHEMBL186468 ZINC13582519 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279375 Fc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C23H25FN4/c24-20-5-7-21(8-6-20)28-13-11-27(12-14-28)10-2-1-3-19-17-26-23-9-4-18(16-25)15-22(19)23/h4-9,15,17,26H,1-3,10-14H2 FAKUMASWBXILCF-UHFFFAOYSA-N 50151992 3-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL188409 D(2) dopamine receptor Rattus norvegicus 4.2 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151992&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10134144 104040126 CHEMBL188409 ZINC13582505 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279380 N#Cc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C24H25N5/c25-16-19-4-7-22(8-5-19)29-13-11-28(12-14-29)10-2-1-3-21-18-27-24-9-6-20(17-26)15-23(21)24/h4-9,15,18,27H,1-3,10-14H2 BPSWBRVXRVOQSP-UHFFFAOYSA-N 50151979 3-{4-[4-(4-Cyano-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL186424 D(2) dopamine receptor Rattus norvegicus 255 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151979&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9929930 104040113 CHEMBL186424 ZINC01893305 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279385 N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4occc4c3)c2c1 InChI=1S/C25H26N4O/c26-17-19-4-6-24-23(15-19)21(18-27-24)3-1-2-9-28-10-12-29(13-11-28)22-5-7-25-20(16-22)8-14-30-25/h4-8,14-16,18,27H,1-3,9-13H2 NHTRRMAECKCPFH-UHFFFAOYSA-N 50151998 3-[4-(4-Benzofuran-5-yl-piperazin-1-yl)-butyl]-1H-indole-5-carbonitrile::CHEMBL184343 D(2) dopamine receptor Rattus norvegicus 8 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151998&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11420033 104040132 CHEMBL184343 ZINC13582546 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279388 COc1ccc(cc1OC)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C25H30N4O2/c1-30-24-9-7-21(16-25(24)31-2)29-13-11-28(12-14-29)10-4-3-5-20-18-27-23-8-6-19(17-26)15-22(20)23/h6-9,15-16,18,27H,3-5,10-14H2,1-2H3 NRNXACCQRCIESQ-UHFFFAOYSA-N 50151999 3-{4-[4-(3,4-Dimethoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL184162 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151999&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11166018 104040133 CHEMBL184162 ZINC13582534 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279389 Oc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C24H29N3O3/c28-20-5-6-22-21(16-20)18(17-25-22)3-1-2-8-26-9-11-27(12-10-26)19-4-7-23-24(15-19)30-14-13-29-23/h4-7,15-17,25,28H,1-3,8-14H2 ZGRIICNJMQCNJE-UHFFFAOYSA-N 50151994 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-1H-indol-5-ol::CHEMBL363055 D(2) dopamine receptor Rattus norvegicus 77 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11395680 104040128 CHEMBL363055 ZINC12356364 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279391 N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4nsnc4c3)c2c1 InChI=1S/C23H24N6S/c24-15-17-4-6-21-20(13-17)18(16-25-21)3-1-2-8-28-9-11-29(12-10-28)19-5-7-22-23(14-19)27-30-26-22/h4-7,13-14,16,25H,1-3,8-12H2 KCOLXAMZGORQBP-UHFFFAOYSA-N 50151980 3-[4-(4-Benzo[1,2,5]thiadiazol-5-yl-piperazin-1-yl)-butyl]-1H-indole-5-carbonitrile::CHEMBL189033 D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151980&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10273418 104040114 CHEMBL189033 ZINC13582540 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279393 NC(=O)c1cc2c(cccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C26H27N5O2/c27-16-18-7-8-22-20(14-18)19(17-29-22)4-1-2-9-30-10-12-31(13-11-30)23-5-3-6-24-21(23)15-25(33-24)26(28)32/h3,5-8,14-15,17,29H,1-2,4,9-13H2,(H2,28,32) WVUXEQNDACAHHK-UHFFFAOYSA-N 50152000 4-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide::CHEMBL188834 D(2) dopamine receptor Rattus norvegicus 6.6 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152000&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11295263 104040134 CHEMBL188834 ZINC13582549 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279397 OC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C25H29N3O4/c29-25(30)18-4-6-22-21(15-18)19(17-26-22)3-1-2-8-27-9-11-28(12-10-27)20-5-7-23-24(16-20)32-14-13-31-23/h4-7,15-17,26H,1-3,8-14H2,(H,29,30) JPOCGVCFCLUQHP-UHFFFAOYSA-N 50152004 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid::CHEMBL188833 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152004&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11454248 104040138 CHEMBL188833 ZINC13582471 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279412 NC(=O)c1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C24H27N5O/c25-16-18-4-9-23-22(15-18)20(17-27-23)3-1-2-10-28-11-13-29(14-12-28)21-7-5-19(6-8-21)24(26)30/h4-9,15,17,27H,1-3,10-14H2,(H2,26,30) VCIWMQRQRVRAAL-UHFFFAOYSA-N 50152014 4-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzamide::CHEMBL187909 D(2) dopamine receptor Rattus norvegicus >270 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152014&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11304169 104040148 CHEMBL187909 ZINC13582530 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279413 NC(=O)c1ccccc1N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C24H27N5O/c25-16-18-8-9-22-21(15-18)19(17-27-22)5-3-4-10-28-11-13-29(14-12-28)23-7-2-1-6-20(23)24(26)30/h1-2,6-9,15,17,27H,3-5,10-14H2,(H2,26,30) FQMVBOXQWIUSJR-UHFFFAOYSA-N 50151991 2-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzamide::CHEMBL189722 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151991&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11259179 104040125 CHEMBL189722 ZINC13582532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279418 C(CCc1c[nH]c2ccccc12)CN1CCN(CC1)c1ccc2OCCOc2c1 InChI=1S/C24H29N3O2/c1-2-7-22-21(6-1)19(18-25-22)5-3-4-10-26-11-13-27(14-12-26)20-8-9-23-24(17-20)29-16-15-28-23/h1-2,6-9,17-18,25H,3-5,10-16H2 DTDAFQBYHBDFSS-UHFFFAOYSA-N 50151997 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL364610 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151997&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11773729 104040131 CHEMBL364610 ZINC13582460 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279419 N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C25H28N4O2/c26-17-19-4-6-23-22(15-19)20(18-27-23)3-1-2-8-28-9-11-29(12-10-28)21-5-7-24-25(16-21)31-14-13-30-24/h4-7,15-16,18,27H,1-3,8-14H2 XDVASTBBJDCVRN-UHFFFAOYSA-N 50151988 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL189709 D(2) dopamine receptor Rattus norvegicus 5.6 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151988&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11362047 104040122 CHEMBL189709 ZINC13582476 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279421 COc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C24H28N4O/c1-29-22-8-6-21(7-9-22)28-14-12-27(13-15-28)11-3-2-4-20-18-26-24-10-5-19(17-25)16-23(20)24/h5-10,16,18,26H,2-4,11-15H2,1H3 JXHSVQARNSBQLW-UHFFFAOYSA-N 50151984 3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL189758 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151984&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9865114 104040118 CHEMBL189758 ZINC13582501 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279429 Oc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C23H26N4O/c24-16-18-4-9-23-22(15-18)19(17-25-23)3-1-2-10-26-11-13-27(14-12-26)20-5-7-21(28)8-6-20/h4-9,15,17,25,28H,1-3,10-14H2 CSGIPYRFITVHEP-UHFFFAOYSA-N 50151993 3-{4-[4-(4-Hydroxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL186654 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11374697 104040127 CHEMBL186654 ZINC13582498 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279430 NC(=O)c1cc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(F)cc23)CC1 InChI=1S/C25H27FN4O2/c26-19-4-6-22-21(15-19)17(16-28-22)3-1-2-8-29-9-11-30(12-10-29)20-5-7-23-18(13-20)14-24(32-23)25(27)31/h4-7,13-16,28H,1-3,8-12H2,(H2,27,31) GGTNSGOMXSGNLN-UHFFFAOYSA-N 50152012 5-{4-[4-(5-Fluoro-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide::CHEMBL360390 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152012&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11316467 104040146 CHEMBL360390 ZINC13582491 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279434 NC(=O)c1cc2ccc(cc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C26H27N5O2/c27-16-18-4-7-23-22(13-18)20(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-6-5-19-14-25(26(28)32)33-24(19)15-21/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32) SRDHJWOHYPFNTJ-UHFFFAOYSA-N 50152008 6-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide::CHEMBL188370 D(2) dopamine receptor Rattus norvegicus 95 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152008&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11191519 104040142 CHEMBL188370 ZINC13582547 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279435 N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCc4c3)c2c1 InChI=1S/C25H28N4O/c26-17-19-4-6-24-23(15-19)21(18-27-24)3-1-2-9-28-10-12-29(13-11-28)22-5-7-25-20(16-22)8-14-30-25/h4-7,15-16,18,27H,1-3,8-14H2 QIXJCHBQCPESEZ-UHFFFAOYSA-N 50152017 3-{4-[4-(2,3-Dihydro-benzofuran-5-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL185631 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152017&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11406934 104040151 CHEMBL185631 ZINC13582538 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279440 Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(cc3)C#N)c2c1 InChI=1S/C23H25FN4/c24-20-6-9-23-22(15-20)19(17-26-23)3-1-2-10-27-11-13-28(14-12-27)21-7-4-18(16-25)5-8-21/h4-9,15,17,26H,1-3,10-14H2 MUXCNTSVWVAFRC-UHFFFAOYSA-N 50152001 4-{4-[4-(5-Fluoro-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzonitrile::CHEMBL185807 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152001&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11394765 104040135 CHEMBL185807 ZINC13582479 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279448 N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCOc4c3)c2c1 InChI=1S/C24H26N4O2/c25-15-18-4-6-22-21(13-18)19(16-26-22)3-1-2-8-27-9-11-28(12-10-27)20-5-7-23-24(14-20)30-17-29-23/h4-7,13-14,16,26H,1-3,8-12,17H2 XBNXSLUDGIRCOM-UHFFFAOYSA-N 50152022 3-[4-(4-Benzo[1,3]dioxol-5-yl-piperazin-1-yl)-butyl]-1H-indole-5-carbonitrile::CHEMBL188799 D(2) dopamine receptor Rattus norvegicus 4.9 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152022&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11249411 104040156 CHEMBL188799 ZINC13582484 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279453 Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C24H28FN3O2/c25-19-4-6-22-21(15-19)18(17-26-22)3-1-2-8-27-9-11-28(12-10-27)20-5-7-23-24(16-20)30-14-13-29-23/h4-7,15-17,26H,1-3,8-14H2 OHRNLIWSDINQNJ-UHFFFAOYSA-N 50152015 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-5-fluoro-1H-indole::CHEMBL186655 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152015&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11751188 104040149 CHEMBL186655 ZINC13582462 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279458 COc1cc(ccc1N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1)C#N InChI=1S/C25H27N5O/c1-31-25-15-20(17-27)6-8-24(25)30-12-10-29(11-13-30)9-3-2-4-21-18-28-23-7-5-19(16-26)14-22(21)23/h5-8,14-15,18,28H,2-4,9-13H2,1H3 LJRGZVNBEHCGFU-UHFFFAOYSA-N 50151995 3-{4-[4-(4-Cyano-2-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL185805 D(2) dopamine receptor Rattus norvegicus 6 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11487741 104040129 CHEMBL185805 ZINC13582513 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279461 NC(=O)c1cc2cc(ccc2[nH]1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C26H28N6O/c27-16-18-4-6-24-22(13-18)19(17-29-24)3-1-2-8-31-9-11-32(12-10-31)21-5-7-23-20(14-21)15-25(30-23)26(28)33/h4-7,13-15,17,29-30H,1-3,8-12H2,(H2,28,33) FWBKATFCLSEGMU-UHFFFAOYSA-N 50152023 5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-1H-indole-2-carboxylic acid amide::CHEMBL366300 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152023&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11306838 104040157 CHEMBL366300 ZINC13582557 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279462 NC(=O)c1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C25H30N4O3/c26-25(30)18-4-6-22-21(15-18)19(17-27-22)3-1-2-8-28-9-11-29(12-10-28)20-5-7-23-24(16-20)32-14-13-31-23/h4-7,15-17,27H,1-3,8-14H2,(H2,26,30) JVGGPWIASBTPGW-UHFFFAOYSA-N 50151948 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide::CHEMBL364592 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11154775 104040082 CHEMBL364592 ZINC13582443 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279469 Oc1ccc(cc1C#N)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C24H25N5O/c25-15-18-4-6-23-22(13-18)19(17-27-23)3-1-2-8-28-9-11-29(12-10-28)21-5-7-24(30)20(14-21)16-26/h4-7,13-14,17,27,30H,1-3,8-12H2 VUPDCEKJOFIAMS-UHFFFAOYSA-N 50152010 3-{4-[4-(3-Cyano-4-hydroxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL363754 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152010&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11751791 104040144 CHEMBL363754 ZINC13582522 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279470 Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4oc(=O)ccc4c3)c2c1 InChI=1S/C25H26FN3O2/c26-20-5-7-23-22(16-20)19(17-27-23)3-1-2-10-28-11-13-29(14-12-28)21-6-8-24-18(15-21)4-9-25(30)31-24/h4-9,15-17,27H,1-3,10-14H2 CMCPGNNULUGJBT-UHFFFAOYSA-N 50152013 6-{4-[4-(5-Fluoro-1H-indol-3-yl)-butyl]-piperazin-1-yl}-chromen-2-one::CHEMBL278471 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152013&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10159048 104040147 CHEMBL278471 ZINC13582494 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279472 Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4oc(cc4c3)C#N)c2c1 InChI=1S/C25H25FN4O/c26-20-4-6-24-23(15-20)18(17-28-24)3-1-2-8-29-9-11-30(12-10-29)21-5-7-25-19(13-21)14-22(16-27)31-25/h4-7,13-15,17,28H,1-3,8-12H2 MXKGLSUKUMBHHW-UHFFFAOYSA-N 50151986 5-{4-[4-(5-Fluoro-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carbonitrile::CHEMBL186219 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151986&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11247047 104040120 CHEMBL186219 ZINC13582486 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279473 O=NCc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C25H30N4O3/c30-27-17-19-4-6-23-22(15-19)20(18-26-23)3-1-2-8-28-9-11-29(12-10-28)21-5-7-24-25(16-21)32-14-13-31-24/h4-7,15-16,18,26H,1-3,8-14,17H2 WMMPFCPGWJRXLU-UHFFFAOYSA-N 50152009 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carbaldehyde oxime::CHEMBL185730 D(2) dopamine receptor Rattus norvegicus 9.4 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152009&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91933039 104040143 CHEMBL185730 ZINC13582468 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279477 NC(=O)c1cc2cccc(N3CCN(CCCCc4c[nH]c5ccc(cc45)C#N)CC3)c2o1 InChI=1S/C26H27N5O2/c27-16-18-7-8-22-21(14-18)20(17-29-22)4-1-2-9-30-10-12-31(13-11-30)23-6-3-5-19-15-24(26(28)32)33-25(19)23/h3,5-8,14-15,17,29H,1-2,4,9-13H2,(H2,28,32) UHUMNQDHQUUJKC-UHFFFAOYSA-N 50152026 7-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide::CHEMBL188530 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11249294 104040160 CHEMBL188530 ZINC12356448 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279479 NC(=O)C1Cc2cc(ccc2O1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C26H29N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-14,17,25,29H,1-3,8-12,15H2,(H2,28,32) URVHPPHCKCBHLS-UHFFFAOYSA-N 50151996 5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-2,3-dihydro-benzofuran-2-carboxylic acid amide::CHEMBL184171 D(2) dopamine receptor Rattus norvegicus 1400 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11260155 104040130 CHEMBL184171 ZINC13582554 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279481 N#Cc1cc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C26H25N5O/c27-16-19-4-6-25-24(13-19)20(18-29-25)3-1-2-8-30-9-11-31(12-10-30)22-5-7-26-21(14-22)15-23(17-28)32-26/h4-7,13-15,18,29H,1-3,8-12H2 GMSXHDFLWANNPI-UHFFFAOYSA-N 50152011 3-{4-[4-(2-Cyano-benzofuran-5-yl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL184556 D(2) dopamine receptor Rattus norvegicus >630 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152011&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11441638 104040145 CHEMBL184556 ZINC13582488 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279486 NC(=O)c1cc2cc(ccc2o1)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C26H27N5O2/c27-16-18-4-6-23-22(13-18)19(17-29-23)3-1-2-8-30-9-11-31(12-10-30)21-5-7-24-20(14-21)15-25(33-24)26(28)32/h4-7,13-15,17,29H,1-3,8-12H2,(H2,28,32) SGEGOXDYSFKCPT-UHFFFAOYSA-N 50151982 5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide::CHEMBL439849::VILAZODONE D(2) dopamine receptor Rattus norvegicus 666 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151982&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search YG7 7LWD 6918314 104040116 70707 CHEMBL439849 DB06684 ZINC01542113 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279490 N#Cc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C23H26N4/c24-17-19-9-10-23-22(16-19)20(18-25-23)6-4-5-11-26-12-14-27(15-13-26)21-7-2-1-3-8-21/h1-3,7-10,16,18,25H,4-6,11-15H2 NMONVBAPWMEOIO-UHFFFAOYSA-N 50152020 3-[4-(4-Phenyl-piperazin-1-yl)-butyl]-1H-indole-5-carbonitrile::CHEMBL188835 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11279810 104040154 CHEMBL188835 ZINC13582496 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279495 COc1cccc(N2CCN(CCCCc3c[nH]c4ccc(cc34)C#N)CC2)c1C#N InChI=1S/C25H27N5O/c1-31-25-7-4-6-24(22(25)17-27)30-13-11-29(12-14-30)10-3-2-5-20-18-28-23-9-8-19(16-26)15-21(20)23/h4,6-9,15,18,28H,2-3,5,10-14H2,1H3 QMRDAGPTZAPMJI-UHFFFAOYSA-N 50152006 3-{4-[4-(2-Cyano-3-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL433968 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152006&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11293864 104040140 CHEMBL433968 ZINC13582516 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279501 NC(=O)c1c(ccc2occc12)N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C26H27N5O2/c27-16-18-4-5-22-21(15-18)19(17-29-22)3-1-2-9-30-10-12-31(13-11-30)23-6-7-24-20(8-14-33-24)25(23)26(28)32/h4-8,14-15,17,29H,1-3,9-13H2,(H2,28,32) PBHMSZAQUTYCEO-UHFFFAOYSA-N 50152021 5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-4-carboxylic acid amide::CHEMBL186138 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152021&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11464867 104040155 CHEMBL186138 ZINC13582563 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279504 COc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C25H31N3O3/c1-29-21-6-7-23-22(17-21)19(18-26-23)4-2-3-9-27-10-12-28(13-11-27)20-5-8-24-25(16-20)31-15-14-30-24/h5-8,16-18,26H,2-4,9-15H2,1H3 VLOAJINDPKHKIO-UHFFFAOYSA-N 50151952 3-{4-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-5-methoxy-1H-indole::CHEMBL188296 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11154398 104040086 CHEMBL188296 ZINC13582406 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279511 COc1ccccc1N1CCN(CCCCc2c[nH]c3ccc(cc23)C#N)CC1 InChI=1S/C24H28N4O/c1-29-24-8-3-2-7-23(24)28-14-12-27(13-15-28)11-5-4-6-20-18-26-22-10-9-19(17-25)16-21(20)22/h2-3,7-10,16,18,26H,4-6,11-15H2,1H3 CIPDKOWUWNPALY-UHFFFAOYSA-N 50152024 3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile::CHEMBL427523 D(2) dopamine receptor Rattus norvegicus 0.700000 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11464427 104040158 CHEMBL427523 ZINC13582503 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50279517 Clc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc4OCCOc4c3)c2c1 InChI=1S/C24H28ClN3O2/c25-19-4-6-22-21(15-19)18(17-26-22)3-1-2-8-27-9-11-28(12-10-27)20-5-7-23-24(16-20)30-14-13-29-23/h4-7,15-17,26H,1-3,8-14H2 HAZSMOOIQWLRTO-UHFFFAOYSA-N 50151987 5-Chloro-3-{4-[4-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL360407 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm040793q 10.7270/Q2513XPS 15341484 Heinrich, T; Bottcher, H; Gericke, R; Bartoszyk, GD; Anzali, S; Seyfried, CA; Greiner, HE; Van Amsterdam, C Merck KGaA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11248217 104040121 CHEMBL360407 ZINC13582464 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50292548 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2.3 ChEMBL 10.1016/j.ejmech.2014.11.012 10.7270/Q2WS8VWN 25461306 Sozio, P; Fiorito, J; Di Giacomo, V; Di Stefano, A; Marinelli, L; Cacciatore, I; Cataldi, A; Pacella, S; Turkez, H; Parenti, C; Rescifina, A; Marrazzo, A Universit£ degli Studi di Chieti Gabriele D'Annunzio http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50292549 O[C@@H](CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1 InChI=1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2/t20-/m0/s1 WNZBBTJFOIOEMP-FQEVSTJZSA-N 50036734 (S)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol::CHEMBL129237 D(2) dopamine receptor Rattus norvegicus 71 ChEMBL 10.1016/j.ejmech.2014.11.012 10.7270/Q2WS8VWN 25461306 Sozio, P; Fiorito, J; Di Giacomo, V; Di Stefano, A; Marinelli, L; Cacciatore, I; Cataldi, A; Pacella, S; Turkez, H; Parenti, C; Rescifina, A; Marrazzo, A Universit£ degli Studi di Chieti Gabriele D'Annunzio http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16048564 103944375 CHEMBL129237 ZINC02516030 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50292550 O[C@H](CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1 InChI=1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2/t20-/m1/s1 WNZBBTJFOIOEMP-HXUWFJFHSA-N 50036738 (R)-4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol::CHEMBL129159 D(2) dopamine receptor Rattus norvegicus 256 ChEMBL 10.1016/j.ejmech.2014.11.012 10.7270/Q2WS8VWN 25461306 Sozio, P; Fiorito, J; Di Giacomo, V; Di Stefano, A; Marinelli, L; Cacciatore, I; Cataldi, A; Pacella, S; Turkez, H; Parenti, C; Rescifina, A; Marrazzo, A Universit£ degli Studi di Chieti Gabriele D'Annunzio http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036738&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24867245 103944379 CHEMBL129159 ZINC04257980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50292551 OC1(CCN(CCC[C@H](OC(=O)CCCc2ccccc2)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C31H35ClFNO3/c32-27-15-13-26(14-16-27)31(36)19-22-34(23-20-31)21-5-9-29(25-11-17-28(33)18-12-25)37-30(35)10-4-8-24-6-2-1-3-7-24/h1-3,6-7,11-18,29,36H,4-5,8-10,19-23H2/t29-/m0/s1 BYFXZIUNDKEGTH-LJAQVGFWSA-N 50059787 CHEMBL3393790 D(2) dopamine receptor Rattus norvegicus >5000 ChEMBL 10.1016/j.ejmech.2014.11.012 10.7270/Q2WS8VWN 25461306 Sozio, P; Fiorito, J; Di Giacomo, V; Di Stefano, A; Marinelli, L; Cacciatore, I; Cataldi, A; Pacella, S; Turkez, H; Parenti, C; Rescifina, A; Marrazzo, A Universit£ degli Studi di Chieti Gabriele D'Annunzio http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059787&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118725676 103955568 CHEMBL3393790 ZINC26748383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50292552 OC1(CCN(CCC[C@@H](OC(=O)CCCc2ccccc2)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C31H35ClFNO3/c32-27-15-13-26(14-16-27)31(36)19-22-34(23-20-31)21-5-9-29(25-11-17-28(33)18-12-25)37-30(35)10-4-8-24-6-2-1-3-7-24/h1-3,6-7,11-18,29,36H,4-5,8-10,19-23H2/t29-/m1/s1 BYFXZIUNDKEGTH-GDLZYMKVSA-N 50059789 CHEMBL3393789 D(2) dopamine receptor Rattus norvegicus >5000 ChEMBL 10.1016/j.ejmech.2014.11.012 10.7270/Q2WS8VWN 25461306 Sozio, P; Fiorito, J; Di Giacomo, V; Di Stefano, A; Marinelli, L; Cacciatore, I; Cataldi, A; Pacella, S; Turkez, H; Parenti, C; Rescifina, A; Marrazzo, A Universit£ degli Studi di Chieti Gabriele D'Annunzio http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059789&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118725675 103955570 CHEMBL3393789 ZINC26738160 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303445 CCCN[C@H]1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1 FASDKYOPVNHBLU-ZETCQYMHSA-N 50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570 D(2) dopamine receptor Rattus norvegicus 9.2 ChEMBL 10.1021/jm049269+ 10.7270/Q2TT4QGT 15801839 Boeckler, F; Ohnmacht, U; Lehmann, T; Utz, W; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 119570 104010405 8356 CHEMBL301265 DB00413 ZINC03781664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303450 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm049269+ 10.7270/Q2TT4QGT 15801839 Boeckler, F; Ohnmacht, U; Lehmann, T; Utz, W; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303452 CCCN(CCC)[C@H]1CCn2c(C1)ccc2C#N InChI=1S/C15H23N3/c1-3-8-17(9-4-2)13-7-10-18-14(11-13)5-6-15(18)12-16/h5-6,13H,3-4,7-11H2,1-2H3/t13-/m0/s1 VQEFMIATWHWTNX-ZDUSSCGKSA-N 50164427 (S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbonitrile::CHEMBL372020 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1021/jm049269+ 10.7270/Q2TT4QGT 15801839 Boeckler, F; Ohnmacht, U; Lehmann, T; Utz, W; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11230330 104050208 CHEMBL372020 ZINC13642130 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303461 CCCN(CCC)[C@H]1CCn2c(C1)ccc2C#N InChI=1S/C15H23N3/c1-3-8-17(9-4-2)13-7-10-18-14(11-13)5-6-15(18)12-16/h5-6,13H,3-4,7-11H2,1-2H3/t13-/m0/s1 VQEFMIATWHWTNX-ZDUSSCGKSA-N 50164427 (S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbonitrile::CHEMBL372020 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm049269+ 10.7270/Q2TT4QGT 15801839 Boeckler, F; Ohnmacht, U; Lehmann, T; Utz, W; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11230330 104050208 CHEMBL372020 ZINC13642130 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303463 CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1 RIOOLQVLOZQLQJ-ZDUSSCGKSA-N 50105731 (S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbaldehyde::CHEMBL316983 D(2) dopamine receptor Rattus norvegicus 79 ChEMBL 10.1021/jm049269+ 10.7270/Q2TT4QGT 15801839 Boeckler, F; Ohnmacht, U; Lehmann, T; Utz, W; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105731&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014924 104001429 CHEMBL316983 ZINC13642125 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50300443 CN1CCN(CC1)C1=Cc2ccccc2Cn2cccc12 InChI=1S/C18H21N3/c1-19-9-11-20(12-10-19)18-13-15-5-2-3-6-16(15)14-21-8-4-7-17(18)21/h2-8,13H,9-12,14H2,1H3 KCYDZGZXAVPYDV-UHFFFAOYSA-N 50162952 11-(4-Methyl-piperazin-1-yl)-5H-benzo[e]pyrrolo[1,2-a]azepine::CHEMBL179775 D(2) dopamine receptor Rattus norvegicus 578 ChEMBL 10.1021/jm049629t 10.7270/Q2R49Q72 15771414 Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Università di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9838572 104049045 CHEMBL179775 ZINC28119505 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50300445 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/jm049629t 10.7270/Q2R49Q72 15771414 Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Università di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50300448 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm049629t 10.7270/Q2R49Q72 15771414 Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Università di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50300451 CN1CCN(CC1)C1=Cc2cc(Cl)ccc2Cn2cccc12 InChI=1S/C18H20ClN3/c1-20-7-9-21(10-8-20)18-12-15-11-16(19)5-4-14(15)13-22-6-2-3-17(18)22/h2-6,11-12H,7-10,13H2,1H3 DZDAGFDMUXEPPJ-UHFFFAOYSA-N 50162954 8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]pyrrolo[1,2-a]azepine::CHEMBL179557 D(2) dopamine receptor Rattus norvegicus 71.1 ChEMBL 10.1021/jm049629t 10.7270/Q2R49Q72 15771414 Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Università di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11186086 104049047 CHEMBL179557 ZINC13611455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50300455 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm049629t 10.7270/Q2R49Q72 15771414 Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Università di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50300465 CN1CCN(CC1)C1=Cn2cccc2Sc2sccc12 InChI=1S/C15H17N3S2/c1-16-6-8-17(9-7-16)13-11-18-5-2-3-14(18)20-15-12(13)4-10-19-15/h2-5,10-11H,6-9H2,1H3 ACRDOIMNOGBPSA-UHFFFAOYSA-N 50162953 9-(4-Methyl-piperazin-1-yl)-3,4-dithia-7a-aza-cyclopenta[f]azulene::CHEMBL180319 D(2) dopamine receptor Rattus norvegicus 8.4 ChEMBL 10.1021/jm049629t 10.7270/Q2R49Q72 15771414 Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Università di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162953&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11324141 104049046 CHEMBL180319 ZINC12355999 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50300466 CN1CCN(CC1)C1=Cn2cccc2Sc2ccccc12 InChI=1S/C17H19N3S/c1-18-9-11-19(12-10-18)15-13-20-8-4-7-17(20)21-16-6-3-2-5-14(15)16/h2-8,13H,9-12H2,1H3 JFLBTRDHDHTNGX-UHFFFAOYSA-N 50137976 9-(4-Methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL367045 D(2) dopamine receptor Rattus norvegicus 17.2 ChEMBL 10.1021/jm049629t 10.7270/Q2R49Q72 15771414 Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Università di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137976&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9796255 104028114 CHEMBL367045 ZINC28014373 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50300469 CN1CCN(CC1)C1=Cn2cccc2Sc2ccc(Cl)cc12 InChI=1S/C17H18ClN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11-12H,7-10H2,1H3 HJNMOCAMMZEOBF-UHFFFAOYSA-N 50137981 7-Chloro-9-(4-methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL426763 D(2) dopamine receptor Rattus norvegicus 0.43 ChEMBL 10.1021/jm049629t 10.7270/Q2R49Q72 15771414 Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Università di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137981&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9797664 104028119 CHEMBL426763 ZINC13532216 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50300471 CN1CCN(CC1)C1=Cc2ccccc2Cn2c(C)ccc12 InChI=1S/C19H23N3/c1-15-7-8-18-19(21-11-9-20(2)10-12-21)13-16-5-3-4-6-17(16)14-22(15)18/h3-8,13H,9-12,14H2,1-2H3 KCHOGJMXHYZZSG-UHFFFAOYSA-N 50162955 3-Methyl-11-(4-methyl-piperazin-1-yl)-5H-benzo[e]pyrrolo[1,2-a]azepine::CHEMBL178564 D(2) dopamine receptor Rattus norvegicus 923.0 ChEMBL 10.1021/jm049629t 10.7270/Q2R49Q72 15771414 Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Università di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11392229 104049048 CHEMBL178564 ZINC13611457 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303348 Clc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc([nH]c3c2=O)-c2ccccc2Cl)CC1 InChI=1S/C24H23Cl2N5O2/c25-17-6-2-1-5-16(17)19-15-20-22(27-19)23(32)31(24(33)28-20)14-11-29-9-12-30(13-10-29)21-8-4-3-7-18(21)26/h1-8,15,27H,9-14H2,(H,28,33) FMDAKEXJKXHJKI-UHFFFAOYSA-N 50164348 6-(2-Chloro-phenyl)-3-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl}-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione::CHEMBL190301 D(2) dopamine receptor Rattus norvegicus 27.79 ChEMBL 10.1021/jm040870h 10.7270/Q2377872 15801833 Patane, E; Pittala, V; Guerrera, F; Salerno, L; Romeo, G; Siracusa, MA; Russo, F; Manetti, F; Botta, M; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11420321 104050172 CHEMBL190301 ZINC13641889 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303352 Cc1ccc(cc1)-c1cc2[nH]c(=O)n(CCN3CCN(CC3)c3ccccc3Cl)c(=O)c2[nH]1 InChI=1S/C25H26ClN5O2/c1-17-6-8-18(9-7-17)20-16-21-23(27-20)24(32)31(25(33)28-21)15-12-29-10-13-30(14-11-29)22-5-3-2-4-19(22)26/h2-9,16,27H,10-15H2,1H3,(H,28,33) DSHAQKQNBSNNEJ-UHFFFAOYSA-N 50164343 3-(2-(4-(2-chlorophenyl)piperazin-1-yl)ethyl)-6-p-tolyl-1H-pyrrolo[3,2-d]pyrimidine-2,4(3H,5H)-dione::3-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-6-p-tolyl-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione::CHEMBL372222 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm040870h 10.7270/Q2377872 15801833 Patane, E; Pittala, V; Guerrera, F; Salerno, L; Romeo, G; Siracusa, MA; Russo, F; Manetti, F; Botta, M; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11751611 104050167 CHEMBL372222 ZINC13641904 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303364 COc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc([nH]c3c2=O)-c2ccc(C)cc2)CC1 InChI=1S/C26H29N5O3/c1-18-7-9-19(10-8-18)20-17-21-24(27-20)25(32)31(26(33)28-21)16-13-29-11-14-30(15-12-29)22-5-3-4-6-23(22)34-2/h3-10,17,27H,11-16H2,1-2H3,(H,28,33) AGKWUSSOLCJWPA-UHFFFAOYSA-N 50164347 3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-6-p-tolyl-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione::CHEMBL190525 D(2) dopamine receptor Rattus norvegicus 19.95 ChEMBL 10.1021/jm040870h 10.7270/Q2377872 15801833 Patane, E; Pittala, V; Guerrera, F; Salerno, L; Romeo, G; Siracusa, MA; Russo, F; Manetti, F; Botta, M; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11487989 104050171 CHEMBL190525 ZINC13641901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303378 COc1ccc(cc1)-c1cc2[nH]c(=O)n(CCCN3CCN(CC3)c3ccccc3OC)c(=O)c2[nH]1 InChI=1S/C27H31N5O4/c1-35-20-10-8-19(9-11-20)21-18-22-25(28-21)26(33)32(27(34)29-22)13-5-12-30-14-16-31(17-15-30)23-6-3-4-7-24(23)36-2/h3-4,6-11,18,28H,5,12-17H2,1-2H3,(H,29,34) NSXWXRWMWCJXJX-UHFFFAOYSA-N 50164345 6-(4-Methoxy-phenyl)-3-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione::CHEMBL190034 D(2) dopamine receptor Rattus norvegicus 2.11 ChEMBL 10.1021/jm040870h 10.7270/Q2377872 15801833 Patane, E; Pittala, V; Guerrera, F; Salerno, L; Romeo, G; Siracusa, MA; Russo, F; Manetti, F; Botta, M; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44399581 104050169 CHEMBL190034 ZINC28470138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303384 COc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc([nH]c3c2=O)-c2ccc(Cl)cc2)CC1 InChI=1S/C25H26ClN5O3/c1-34-22-5-3-2-4-21(22)30-13-10-29(11-14-30)12-15-31-24(32)23-20(28-25(31)33)16-19(27-23)17-6-8-18(26)9-7-17/h2-9,16,27H,10-15H2,1H3,(H,28,33) MOIUZUKSUMOMKZ-UHFFFAOYSA-N 50164355 6-(4-Chloro-phenyl)-3-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione::CHEMBL189437 D(2) dopamine receptor Rattus norvegicus 3.64 ChEMBL 10.1021/jm040870h 10.7270/Q2377872 15801833 Patane, E; Pittala, V; Guerrera, F; Salerno, L; Romeo, G; Siracusa, MA; Russo, F; Manetti, F; Botta, M; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11454443 104050179 CHEMBL189437 ZINC13641895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303385 Clc1ccc(cc1)-c1cc2[nH]c(=O)n(CCN3CCN(CC3)c3ccccc3Cl)c(=O)c2[nH]1 InChI=1S/C24H23Cl2N5O2/c25-17-7-5-16(6-8-17)19-15-20-22(27-19)23(32)31(24(33)28-20)14-11-29-9-12-30(13-10-29)21-4-2-1-3-18(21)26/h1-8,15,27H,9-14H2,(H,28,33) DMQPHRQAXQYLGW-UHFFFAOYSA-N 50164350 6-(4-Chloro-phenyl)-3-{2-[4-(2-chloro-phenyl)-piperazin-1-yl]-ethyl}-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione::CHEMBL191425 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm040870h 10.7270/Q2377872 15801833 Patane, E; Pittala, V; Guerrera, F; Salerno, L; Romeo, G; Siracusa, MA; Russo, F; Manetti, F; Botta, M; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11237063 104050174 CHEMBL191425 ZINC13641898 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303393 Clc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc[nH]c3c2=O)CC1 InChI=1S/C18H20ClN5O2/c19-13-3-1-2-4-15(13)23-10-7-22(8-11-23)9-12-24-17(25)16-14(5-6-20-16)21-18(24)26/h1-6,20H,7-12H2,(H,21,26) SZUAWSHWOGGCTK-UHFFFAOYSA-N 50164344 3-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-1,5-dihydro-pyrrolo[3,2-d]pyrimidine-2,4-dione::CHEMBL190384 D(2) dopamine receptor Rattus norvegicus 322.1 ChEMBL 10.1021/jm040870h 10.7270/Q2377872 15801833 Patane, E; Pittala, V; Guerrera, F; Salerno, L; Romeo, G; Siracusa, MA; Russo, F; Manetti, F; Botta, M; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50164344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50164344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11280247 104050168 CHEMBL190384 ZINC13641862 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303428 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1021/jm049269+ 10.7270/Q2TT4QGT 15801839 Boeckler, F; Ohnmacht, U; Lehmann, T; Utz, W; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303435 CCCN[C@H]1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1 FASDKYOPVNHBLU-ZETCQYMHSA-N 50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm049269+ 10.7270/Q2TT4QGT 15801839 Boeckler, F; Ohnmacht, U; Lehmann, T; Utz, W; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 119570 104010405 8356 CHEMBL301265 DB00413 ZINC03781664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50303438 CCCN(CCC)[C@H]1CCn2c(C1)ccc2C=O InChI=1S/C15H24N2O/c1-3-8-16(9-4-2)13-7-10-17-14(11-13)5-6-15(17)12-18/h5-6,12-13H,3-4,7-11H2,1-2H3/t13-/m0/s1 RIOOLQVLOZQLQJ-ZDUSSCGKSA-N 50105731 (S)-7-Dipropylamino-5,6,7,8-tetrahydro-indolizine-3-carbaldehyde::CHEMBL316983 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm049269+ 10.7270/Q2TT4QGT 15801839 Boeckler, F; Ohnmacht, U; Lehmann, T; Utz, W; Hubner, H; Gmeiner, P Friedrich-Alexander University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50105731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50105731&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014924 104001429 CHEMBL316983 ZINC13642125 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50317136 FC(F)(F)c1cccc(c1)N1CCN(CCCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1 InChI=1S/C23H26F3N3O3/c24-23(25,26)17-3-1-4-18(14-17)28-10-8-27(9-11-28)7-2-12-32-29-21(30)19-15-5-6-16(13-15)20(19)22(29)31/h1,3-6,14-16,19-20H,2,7-13H2 HHOJHFKKQUQMQF-UHFFFAOYSA-N 50171885 4-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-propoxy}-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione::CHEMBL191226 D(2) dopamine receptor Rattus norvegicus 670 ChEMBL 10.1021/jm050246k 10.7270/Q2TM79N5 16107148 Fiorino, F; Perissutti, E; Severino, B; Santagada, V; Cirillo, D; Terracciano, S; Massarelli, P; Bruni, G; Collavoli, E; Renner, C; Caliendo, G Università di Napoli "Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44399174 104058061 CHEMBL191226 ZINC13671675 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50317151 Clc1ccccc1N1CCN(CCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1 InChI=1S/C21H24ClN3O3/c22-16-3-1-2-4-17(16)24-9-7-23(8-10-24)11-12-28-25-20(26)18-14-5-6-15(13-14)19(18)21(25)27/h1-6,14-15,18-19H,7-13H2 AJURAEJVSNFUBV-UHFFFAOYSA-N 50171890 4-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethoxy}-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione::CHEMBL426813 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm050246k 10.7270/Q2TM79N5 16107148 Fiorino, F; Perissutti, E; Severino, B; Santagada, V; Cirillo, D; Terracciano, S; Massarelli, P; Bruni, G; Collavoli, E; Renner, C; Caliendo, G Università di Napoli "Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44399126 104058066 CHEMBL426813 ZINC28477268 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50317156 COc1ccccc1N1CCN(CCCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1 InChI=1S/C23H29N3O4/c1-29-19-6-3-2-5-18(19)25-12-10-24(11-13-25)9-4-14-30-26-22(27)20-16-7-8-17(15-16)21(20)23(26)28/h2-3,5-8,16-17,20-21H,4,9-15H2,1H3 QCWCXCPPQKWURU-UHFFFAOYSA-N 50171884 4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione::CHEMBL189384 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm050246k 10.7270/Q2TM79N5 16107148 Fiorino, F; Perissutti, E; Severino, B; Santagada, V; Cirillo, D; Terracciano, S; Massarelli, P; Bruni, G; Collavoli, E; Renner, C; Caliendo, G Università di Napoli "Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11418453 104058060 CHEMBL189384 ZINC28471032 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50317163 FC(F)(F)c1cccc(c1)N1CCN(CCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1 InChI=1S/C22H24F3N3O3/c23-22(24,25)16-2-1-3-17(13-16)27-8-6-26(7-9-27)10-11-31-28-20(29)18-14-4-5-15(12-14)19(18)21(28)30/h1-5,13-15,18-19H,6-12H2 SDJKZQGULMYBGL-UHFFFAOYSA-N 50171886 4-{2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-ethoxy}-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione::CHEMBL364530 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm050246k 10.7270/Q2TM79N5 16107148 Fiorino, F; Perissutti, E; Severino, B; Santagada, V; Cirillo, D; Terracciano, S; Massarelli, P; Bruni, G; Collavoli, E; Renner, C; Caliendo, G Università di Napoli "Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171886&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44398782 104058062 CHEMBL364530 ZINC28468911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50325899 COc1cccc2cc(oc12)C(=O)NCCCCN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C24H27Cl2N3O3/c1-31-20-9-4-6-17-16-21(32-23(17)20)24(30)27-10-2-3-11-28-12-14-29(15-13-28)19-8-5-7-18(25)22(19)26/h4-9,16H,2-3,10-15H2,1H3,(H,27,30) OVCZXWAILUTIOQ-UHFFFAOYSA-N 50176070 7-Methoxy-benzofuran-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL196476::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-7-methoxybenzofuran-2-carboxamide D(2) dopamine receptor Rattus norvegicus 720 ChEMBL 10.1021/jm050171k 10.7270/Q2H994SR 16250661 Turolla, EA; Matarrese, M; Belloli, S; Moresco, RM; Simonelli, P; Todde, S; Fazio, F; Magni, F; Kienle, MG; Leopoldo, M; Berardi, F; Colabufo, NA; Lacivita, E; Perrone, R University of Milano/Bicocca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50176070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50176070&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10254390 104061744 CHEMBL196476 ZINC13492671 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50325901 COc1c(ccc2ccccc12)C(=O)NCCCCN1CCN(CC1)c1cccc(Cl)c1Cl InChI=1S/C26H29Cl2N3O2/c1-33-25-20-8-3-2-7-19(20)11-12-21(25)26(32)29-13-4-5-14-30-15-17-31(18-16-30)23-10-6-9-22(27)24(23)28/h2-3,6-12H,4-5,13-18H2,1H3,(H,29,32) JIFZJJHUCHFIGP-UHFFFAOYSA-N 50122041 1-Methoxy-naphthalene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL345820::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-1-methoxy-2-naphthamide D(2) dopamine receptor Rattus norvegicus 720 ChEMBL 10.1021/jm050171k 10.7270/Q2H994SR 16250661 Turolla, EA; Matarrese, M; Belloli, S; Moresco, RM; Simonelli, P; Todde, S; Fazio, F; Magni, F; Kienle, MG; Leopoldo, M; Berardi, F; Colabufo, NA; Lacivita, E; Perrone, R University of Milano/Bicocca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122041&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10961938 104014754 CHEMBL345820 ZINC13492664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50336055 NCCc1c(Cl)sc2[nH]c(=O)c(c(O)c12)-c1cccc(Oc2ccccc2)c1 InChI=1S/C21H17ClN2O3S/c22-19-15(9-10-23)17-18(25)16(20(26)24-21(17)28-19)12-5-4-8-14(11-12)27-13-6-2-1-3-7-13/h1-8,11H,9-10,23H2,(H2,24,25,26) YIMSHHMJWBMJCZ-UHFFFAOYSA-N 50181443 3-(2-aminoethyl)-2-chloro-4-hydroxy-5-(3-phenoxyphenyl)thieno[2,3-b]pyridin-6(7H)-one::CHEMBL202126 D(2) dopamine receptor Rattus norvegicus >30000 ChEMBL 10.1021/jm0503493 10.7270/Q2513XS4 16451052 Buchstaller, HP; Siebert, CD; Steinmetz, R; Frank, I; Berger, ML; Gottschlich, R; Leibrock, J; Krug, M; Steinhilber, D; Noe, CR Johann Wolfgang Goethe University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54706507 104066282 CHEMBL202126 ZINC13680079 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50336104 NCCc1c(Cl)sc2[nH]c(=O)c(-c3ccccc3)c(O)c12 InChI=1S/C15H13ClN2O2S/c16-13-9(6-7-17)11-12(19)10(8-4-2-1-3-5-8)14(20)18-15(11)21-13/h1-5H,6-7,17H2,(H2,18,19,20) NFCXBOFCIPCUSM-UHFFFAOYSA-N 50241006 3-(2-aminoethyl)-2-chloro-4-hydroxy-5-phenylthieno[2,3-b]pyridin-6(7H)-one::CHEMBL380963 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm0503493 10.7270/Q2513XS4 16451052 Buchstaller, HP; Siebert, CD; Steinmetz, R; Frank, I; Berger, ML; Gottschlich, R; Leibrock, J; Krug, M; Steinhilber, D; Noe, CR Johann Wolfgang Goethe University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241006&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54690866 104098549 CHEMBL380963 ZINC13680030 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50353478 COc1ccccc1N1CCN(CCCCN2C(=O)NC3(CCc4ccccc34)C2=O)CC1 InChI=1S/C26H32N4O3/c1-33-23-11-5-4-10-22(23)29-18-16-28(17-19-29)14-6-7-15-30-24(31)26(27-25(30)32)13-12-20-8-2-3-9-21(20)26/h2-5,8-11H,6-7,12-19H2,1H3,(H,27,32) QGKLLEYCXJRYRS-UHFFFAOYSA-N 50094292 CHEMBL3589977 D(2) dopamine receptor Rattus norvegicus 104 ChEMBL 10.1016/j.bmc.2015.04.026 10.7270/Q23T9JZD 25936259 Czopek, A; Kolaczkowski, M; Bucki, A; Byrtus, H; Pawlowski, M; Kazek, G; Bojarski, AJ; Piaskowska, A; Kalinowska-Tluscik, J; Partyka, A; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094292&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122181251 318473478 CHEMBL3589977 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50353488 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)NC3(CCC(CC3)c3ccccc3)C2=O)CC1 InChI=1S/C17H22O2/c1-2-3-11-14-17(19)15-12-9-7-5-4-6-8-10-13-16-18/h7,9,12,15,18H,2-3,10-11,13-14,16H2,1H3/b9-7+,15-12+ CNWDQIWOBGMLNM-KDFHGORWSA-N 50094273 CHEMBL3590095 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmc.2015.04.026 10.7270/Q23T9JZD 25936259 Czopek, A; Kolaczkowski, M; Bucki, A; Byrtus, H; Pawlowski, M; Kazek, G; Bojarski, AJ; Piaskowska, A; Kalinowska-Tluscik, J; Partyka, A; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122181343 103992172 CHEMBL3590095 ZINC13835254 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50353489 Clc1cccc(c1)N1CCN(CCCCN2C(=O)NC3(CCC(CC3)c3ccccc3)C2=O)CC1 InChI=1S/C19H24O3/c1-3-15-19(21)16-13-11-9-7-5-4-6-8-10-12-14-17-22-18(2)20/h5,7,9,11,13,16,19,21H,3,12,14-15,17H2,1-2H3/b7-5+,11-9+,16-13+/t19-/m1/s1 OHFODISPAOYBLZ-PDYGGIGGSA-N 50094274 CHEMBL3590094 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmc.2015.04.026 10.7270/Q23T9JZD 25936259 Czopek, A; Kolaczkowski, M; Bucki, A; Byrtus, H; Pawlowski, M; Kazek, G; Bojarski, AJ; Piaskowska, A; Kalinowska-Tluscik, J; Partyka, A; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094274&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122181342 103992173 CHEMBL3590094 ZINC13835246 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50353490 COc1ccccc1N1CCN(CCCCN2C(=O)NC3(CCC(CC3)c3ccccc3)C2=O)CC1 InChI=1S/C21H29NO2/c1-3-5-19-22-21(24)18-15-13-11-9-7-6-8-10-12-14-17-20(23)16-4-2/h6,8,10,12,14,17,20,23H,3-5,15-16,18-19H2,1-2H3,(H,22,24)/b8-6+,12-10+,17-14+/t20-/m1/s1 CAGCYHDAYVSDPK-ZCJAXSLHSA-N 50094275 CHEMBL3590093 D(2) dopamine receptor Rattus norvegicus 79 ChEMBL 10.1016/j.bmc.2015.04.026 10.7270/Q23T9JZD 25936259 Czopek, A; Kolaczkowski, M; Bucki, A; Byrtus, H; Pawlowski, M; Kazek, G; Bojarski, AJ; Piaskowska, A; Kalinowska-Tluscik, J; Partyka, A; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094275&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122181341 103992174 CHEMBL3590093 ZINC13835259 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50353491 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)NC3(CCCc4ccccc34)C2=O)CC1 InChI=1S/C15H18O7/c1-12(2,18)6-7-10(16)20-8(6)9-13(3)14(7,19)4-5-15(13,22-5)11(17)21-9/h5-9,18-19H,4H2,1-3H3/t5?,6-,7+,8+,9+,13+,14+,15?/m0/s1 RYEFFICCPKWYML-NEIGCKIQSA-N 50094277 CHEMBL3590091 D(2) dopamine receptor Rattus norvegicus 608 ChEMBL 10.1016/j.bmc.2015.04.026 10.7270/Q23T9JZD 25936259 Czopek, A; Kolaczkowski, M; Bucki, A; Byrtus, H; Pawlowski, M; Kazek, G; Bojarski, AJ; Piaskowska, A; Kalinowska-Tluscik, J; Partyka, A; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122181339 103992176 CHEMBL3590091 ZINC27519907 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50353492 Clc1cccc(c1)N1CCN(CCCCN2C(=O)NC3(CCCc4ccccc34)C2=O)CC1 InChI=1S/C11H15N3O5/c1-2-11(5-15)8(17)7(16)9(19-11)14-4-3-6(12)13-10(14)18/h1,3-4,6-9,15-17H,5,12H2,(H,13,18)/t6?,7?,8-,9-,11-/m1/s1 AHPUQKGGHKGABH-DOVWHHSFSA-N 50094280 CHEMBL3590090 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1016/j.bmc.2015.04.026 10.7270/Q23T9JZD 25936259 Czopek, A; Kolaczkowski, M; Bucki, A; Byrtus, H; Pawlowski, M; Kazek, G; Bojarski, AJ; Piaskowska, A; Kalinowska-Tluscik, J; Partyka, A; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122181338 103992179 CHEMBL3590090 ZINC27519677 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50353493 COc1ccccc1N1CCN(CCCCN2C(=O)NC3(CCCc4ccccc34)C2=O)CC1 InChI=1S/C27H34N4O3/c1-34-24-13-5-4-12-23(24)30-19-17-29(18-20-30)15-6-7-16-31-25(32)27(28-26(31)33)14-8-10-21-9-2-3-11-22(21)27/h2-5,9,11-13H,6-8,10,14-20H2,1H3,(H,28,33) BUVAGKGIBHOSMY-UHFFFAOYSA-N 50094283 CHEMBL3590089 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1016/j.bmc.2015.04.026 10.7270/Q23T9JZD 25936259 Czopek, A; Kolaczkowski, M; Bucki, A; Byrtus, H; Pawlowski, M; Kazek, G; Bojarski, AJ; Piaskowska, A; Kalinowska-Tluscik, J; Partyka, A; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122181337 318473474 CHEMBL3590089 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50353494 O=C1NC2(CCCc3ccccc23)C(=O)N1CCCCN1CCN(CC1)c1ccccc1 InChI=1S/C26H32N4O2/c31-24-26(14-8-10-21-9-4-5-13-23(21)26)27-25(32)30(24)16-7-6-15-28-17-19-29(20-18-28)22-11-2-1-3-12-22/h1-5,9,11-13H,6-8,10,14-20H2,(H,27,32) QKAAUECANFAGOP-UHFFFAOYSA-N 50094289 CHEMBL3590088 D(2) dopamine receptor Rattus norvegicus 743 ChEMBL 10.1016/j.bmc.2015.04.026 10.7270/Q23T9JZD 25936259 Czopek, A; Kolaczkowski, M; Bucki, A; Byrtus, H; Pawlowski, M; Kazek, G; Bojarski, AJ; Piaskowska, A; Kalinowska-Tluscik, J; Partyka, A; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122181336 318473475 CHEMBL3590088 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50353495 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)NC3(CCc4ccccc34)C2=O)CC1 InChI=1S/C26H29F3N4O2/c27-26(28,29)20-7-5-8-21(18-20)32-16-14-31(15-17-32)12-3-4-13-33-23(34)25(30-24(33)35)11-10-19-6-1-2-9-22(19)25/h1-2,5-9,18H,3-4,10-17H2,(H,30,35) HFQUPGBANBTKLO-UHFFFAOYSA-N 50094290 CHEMBL3590087 D(2) dopamine receptor Rattus norvegicus 412 ChEMBL 10.1016/j.bmc.2015.04.026 10.7270/Q23T9JZD 25936259 Czopek, A; Kolaczkowski, M; Bucki, A; Byrtus, H; Pawlowski, M; Kazek, G; Bojarski, AJ; Piaskowska, A; Kalinowska-Tluscik, J; Partyka, A; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122181335 318473476 CHEMBL3590087 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50353496 Clc1cccc(c1)N1CCN(CCCCN2C(=O)NC3(CCc4ccccc34)C2=O)CC1 InChI=1S/C25H29ClN4O2/c26-20-7-5-8-21(18-20)29-16-14-28(15-17-29)12-3-4-13-30-23(31)25(27-24(30)32)11-10-19-6-1-2-9-22(19)25/h1-2,5-9,18H,3-4,10-17H2,(H,27,32) KCCOADNQWWNYBT-UHFFFAOYSA-N 50094291 CHEMBL3589978 D(2) dopamine receptor Rattus norvegicus 539 ChEMBL 10.1016/j.bmc.2015.04.026 10.7270/Q23T9JZD 25936259 Czopek, A; Kolaczkowski, M; Bucki, A; Byrtus, H; Pawlowski, M; Kazek, G; Bojarski, AJ; Piaskowska, A; Kalinowska-Tluscik, J; Partyka, A; Wesolowska, A Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50094291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50094291&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122181252 318473477 CHEMBL3589978 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50377203 COC(=O)C1(CC1CN1CCC(O)(CC1)c1ccccc1)c1ccc(C)cc1 InChI=1S/C24H29NO3/c1-18-8-10-20(11-9-18)24(22(26)28-2)16-21(24)17-25-14-12-23(27,13-15-25)19-6-4-3-5-7-19/h3-11,21,27H,12-17H2,1-2H3 BDSYECBSUUOPCT-UHFFFAOYSA-N 50206578 CHEMBL222301::cis-((+/-)-Methyl(1R,2S/1S,2R)-2-[(4-Hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate::methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperidin-1-yl)-methyl]-1-(4-methylphenyl)cyclopropanecarboxylate D(2) dopamine receptor Rattus norvegicus 1285 ChEMBL 10.1021/jm0611197 10.7270/Q2GH9HN8 17328523 Prezzavento, O; Campisi, A; Ronsisvalle, S; Li Volti, G; Marrazzo, A; Bramanti, V; Cannavo, G; Vanella, L; Cagnotto, A; Mennini, T; Ientile, R; Ronsisvalle, G University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16726095 104084577 CHEMBL222301 6676 ZINC28635563 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50372080 CC(C)N1CCN(CC1)C(CN1CCN(CCCc2ccccc2-c2ccc(F)cc2)CC1)c1ccc(F)cc1 InChI=1S/C34H44F2N4/c1-27(2)39-22-24-40(25-23-39)34(30-11-15-32(36)16-12-30)26-38-20-18-37(19-21-38)17-5-7-28-6-3-4-8-33(28)29-9-13-31(35)14-10-29/h3-4,6,8-16,27,34H,5,7,17-26H2,1-2H3 VDJPVMKXBQABSL-UHFFFAOYSA-N 50202924 (+/-)-1-[3-(4'-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(4-isopropylpiperazin-1-yl)ethyl]piperazine::CHEMBL226281 D(2) dopamine receptor Rattus norvegicus 721 ChEMBL 10.1016/j.bmc.2006.12.039 10.7270/Q2C53KHN 17234422 Nozawa, D; Okubo, T; Ishii, T; Kakinuma, H; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423463 104082293 CHEMBL226281 ZINC28646382 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50372087 CC(C)N1CCN(CC1)C(CN1CCN(CCCc2cc(F)ccc2-c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C34H44F2N4/c1-27(2)39-21-23-40(24-22-39)34(29-10-12-31(35)13-11-29)26-38-19-17-37(18-20-38)16-6-9-30-25-32(36)14-15-33(30)28-7-4-3-5-8-28/h3-5,7-8,10-15,25,27,34H,6,9,16-24,26H2,1-2H3 VEHVBAJFWBANGR-UHFFFAOYSA-N 50202926 (+/-)-1-[3-(4-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-4-isopropylpiperazin-1-yl)ethyl]piperazine::CHEMBL226125 D(2) dopamine receptor Rattus norvegicus 721 ChEMBL 10.1016/j.bmc.2006.12.039 10.7270/Q2C53KHN 17234422 Nozawa, D; Okubo, T; Ishii, T; Kakinuma, H; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202926&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423456 104082295 CHEMBL226125 ZINC28646344 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50372094 CC(C)N1CCN(CC1)C(CN1CCN(CCCc2c(Cl)cccc2-c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C34H44ClFN4/c1-27(2)39-22-24-40(25-23-39)34(29-13-15-30(36)16-14-29)26-38-20-18-37(19-21-38)17-7-11-32-31(10-6-12-33(32)35)28-8-4-3-5-9-28/h3-6,8-10,12-16,27,34H,7,11,17-26H2,1-2H3 VFCUBGIDVRNDJS-UHFFFAOYSA-N 50202929 (+/-)-1-[3-(3-chlorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-4-isopropylpiperazin-1-yl)ethyl]piperazine::CHEMBL226177 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2006.12.039 10.7270/Q2C53KHN 17234422 Nozawa, D; Okubo, T; Ishii, T; Kakinuma, H; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202929&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423458 104082298 CHEMBL226177 ZINC28646355 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50372114 CC(C)N1CCN(CC1)C(CN1CCN(CCCc2cccc(F)c2-c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C34H44F2N4/c1-27(2)39-22-24-40(25-23-39)33(28-13-15-31(35)16-14-28)26-38-20-18-37(19-21-38)17-7-11-30-10-6-12-32(36)34(30)29-8-4-3-5-9-29/h3-6,8-10,12-16,27,33H,7,11,17-26H2,1-2H3 XHPVWBPEZTWPSN-UHFFFAOYSA-N 50202941 (+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-4-isopropylpiperazin-1-yl)ethyl]piperazine::CHEMBL226123 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2006.12.039 10.7270/Q2C53KHN 17234422 Nozawa, D; Okubo, T; Ishii, T; Kakinuma, H; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423454 104082310 CHEMBL226123 ZINC28646330 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50372157 CC(C)N1CCN(CC1)C(CN1CCN(CCCc2ccccc2-c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C34H45FN4/c1-28(2)38-23-25-39(26-24-38)34(31-14-16-32(35)17-15-31)27-37-21-19-36(20-22-37)18-8-12-30-11-6-7-13-33(30)29-9-4-3-5-10-29/h3-7,9-11,13-17,28,34H,8,12,18-27H2,1-2H3 UOUWWVWWIQEODA-UHFFFAOYSA-N 50202930 (+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophenyl)-2-(4-isopropylpiperazin-1-yl)ethyl]piperazine::CHEMBL226025 D(2) dopamine receptor Rattus norvegicus 645 ChEMBL 10.1016/j.bmc.2006.12.039 10.7270/Q2C53KHN 17234422 Nozawa, D; Okubo, T; Ishii, T; Kakinuma, H; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10239507 104082299 CHEMBL226025 ZINC28646306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50372180 CC(C)N1CCN(CC1)C(CN1CCN(CCCc2ccc(F)cc2-c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C34H44F2N4/c1-27(2)39-21-23-40(24-22-39)34(30-11-13-31(35)14-12-30)26-38-19-17-37(18-20-38)16-6-9-29-10-15-32(36)25-33(29)28-7-4-3-5-8-28/h3-5,7-8,10-15,25,27,34H,6,9,16-24,26H2,1-2H3 DRSLEYLXVNRDKA-UHFFFAOYSA-N 50202934 (+/-)-1-[3-(5-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-4-isopropylpiperazin-1-yl)ethyl]piperazine::CHEMBL226124 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2006.12.039 10.7270/Q2C53KHN 17234422 Nozawa, D; Okubo, T; Ishii, T; Kakinuma, H; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202934&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423455 104082303 CHEMBL226124 ZINC28646338 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50372185 CC(C)N1CCN(CC1)C(CN1CCN(CCCc2c(C)cccc2-c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C35H47FN4/c1-28(2)39-23-25-40(26-24-39)35(31-14-16-32(36)17-15-31)27-38-21-19-37(20-22-38)18-8-13-33-29(3)9-7-12-34(33)30-10-5-4-6-11-30/h4-7,9-12,14-17,28,35H,8,13,18-27H2,1-3H3 JBXYADWMJLOTTL-UHFFFAOYSA-N 50202933 (+/-)-1-[2-(4-fluorophenyl)-2-(4-isopropylpiperazin-1-yl)ethyl]-4-[3-(3-methylbiphenyl-2-yl)propyl]piperazine::CHEMBL226227 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2006.12.039 10.7270/Q2C53KHN 17234422 Nozawa, D; Okubo, T; Ishii, T; Kakinuma, H; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202933&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423459 104082302 CHEMBL226227 ZINC28646360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50372191 CC(C)N1CCN(CC1)C(CN1CCN(CCCc2ccccc2-c2cccc(F)c2)CC1)c1ccc(F)cc1 InChI=1S/C34H44F2N4/c1-27(2)39-21-23-40(24-22-39)34(29-12-14-31(35)15-13-29)26-38-19-17-37(18-20-38)16-6-9-28-7-3-4-11-33(28)30-8-5-10-32(36)25-30/h3-5,7-8,10-15,25,27,34H,6,9,16-24,26H2,1-2H3 OSBBNXANCGTXBW-UHFFFAOYSA-N 50202938 (+/-)-1-[3-(3'-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(4-isopropylpiperazin-1-yl)ethyl]piperazine::CHEMBL226280 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2006.12.039 10.7270/Q2C53KHN 17234422 Nozawa, D; Okubo, T; Ishii, T; Kakinuma, H; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202938&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423462 104082307 CHEMBL226280 ZINC28646376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50372199 CC(C)N1CCN(CC1)C(CN1CCN(CCCc2c(F)cccc2-c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C34H44F2N4/c1-27(2)39-22-24-40(25-23-39)34(29-13-15-30(35)16-14-29)26-38-20-18-37(19-21-38)17-7-11-32-31(10-6-12-33(32)36)28-8-4-3-5-9-28/h3-6,8-10,12-16,27,34H,7,11,17-26H2,1-2H3 PAVIGVDFHAXYTL-UHFFFAOYSA-N 50202947 (+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(4-isopropylpiperazin-1-yl)ethyl]piperazine::CHEMBL226176 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2006.12.039 10.7270/Q2C53KHN 17234422 Nozawa, D; Okubo, T; Ishii, T; Kakinuma, H; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423457 104082316 CHEMBL226176 ZINC28646350 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50367265 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 0.40 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50367297 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm060662k 10.7270/Q25X28MM 17149874 Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD; Nakane, M; Miller, LN; Uchic, ME; Terranova, MA; El-Kouhen, OF; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Chang, R; Martino, BR; Wetter, JM; Marsh, KC; Martin, R; Darbyshire, JF; Gintant, G; Hsieh, GC; Moreland, RB; Sullivan, JP; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376927 COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(=O)C3CCCC3)C2=O)CC1 InChI=1S/C25H36N4O4/c1-33-22-11-5-4-10-21(22)28-16-14-27(15-17-28)12-6-7-13-29-23(30)18-20(25(29)32)26-24(31)19-8-2-3-9-19/h4-5,10-11,19-20H,2-3,6-9,12-18H2,1H3,(H,26,31)/t20-/m0/s1 DJFTUKCLDFIJPC-FQEVSTJZSA-N 50186240 (S)-N-(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,5-dioxopyrrolidin-3-yl)cyclopentanecarboxamide::CHEMBL207493::N-((S)-1-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}pyrrolidin-2,5-dion-3-yl)cyclopentanecarboxamide D(2) dopamine receptor Rattus norvegicus 905 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50186240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50186240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44412838 104070289 CHEMBL207493 ZINC36187826 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376930 Clc1cccc(c1)N1CCN(CCCC[C@@H]2CCCN2C(=O)C23CC4CC(CC(C4)C2)C3)CC1 InChI=1S/C29H42ClN3O/c30-25-5-3-7-27(18-25)32-13-11-31(12-14-32)9-2-1-6-26-8-4-10-33(26)28(34)29-19-22-15-23(20-29)17-24(16-22)21-29/h3,5,7,18,22-24,26H,1-2,4,6,8-17,19-21H2/t22?,23?,24?,26-,29?/m1/s1 KYUIGEMGEGFVHQ-KXAIUKJUSA-N 50206346 1-(adamantylcarbonyl)-N-{4-[4-(3-chlorophenyl)piperazin-1-yl]butyl}-L-prolinamide::CHEMBL232449 D(2) dopamine receptor Rattus norvegicus 1780 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431021 104084480 CHEMBL232449 ZINC28820036 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376933 COc1ccccc1N1CCN(CCCC[C@@H]2CCCN2C(=O)C2CCCCC2)CC1 InChI=1S/C26H41N3O2/c1-31-25-15-6-5-14-24(25)28-20-18-27(19-21-28)16-8-7-12-23-13-9-17-29(23)26(30)22-10-3-2-4-11-22/h5-6,14-15,22-23H,2-4,7-13,16-21H2,1H3/t23-/m1/s1 KVMZOTTULOREGX-HSZRJFAPSA-N 50206348 1-(cyclohexylcarbonyl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-L-prolinamide::CHEMBL232035 D(2) dopamine receptor Rattus norvegicus 3595 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431014 104084482 CHEMBL232035 ZINC28819994 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376934 COc1ccccc1N1CCN(CCCC[C@@H]2CCCN2C(=O)CC2CC3CCC2C3)CC1 InChI=1S/C28H43N3O2/c1-33-27-10-3-2-9-26(27)30-17-15-29(16-18-30)13-5-4-7-25-8-6-14-31(25)28(32)21-24-20-22-11-12-23(24)19-22/h2-3,9-10,22-25H,4-8,11-21H2,1H3/t22?,23?,24?,25-/m1/s1 VCCYTIFUNPMUAI-FVPXYTCKSA-N 50206347 1-((bicyclo[2.2.1]heptan-2-yl)acetyl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-L-prolinamide::CHEMBL232036 D(2) dopamine receptor Rattus norvegicus 1365 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431015 104084481 CHEMBL232036 ZINC28820007 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376941 COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(=O)C3CCCCC3)C2=O)CC1 InChI=1S/C26H38N4O4/c1-34-23-12-6-5-11-22(23)29-17-15-28(16-18-29)13-7-8-14-30-24(31)19-21(26(30)33)27-25(32)20-9-3-2-4-10-20/h5-6,11-12,20-21H,2-4,7-10,13-19H2,1H3,(H,27,32)/t21-/m0/s1 QWILWYRTJFBACP-NRFANRHFSA-N 50186244 (S)-N-(1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,5-dioxopyrrolidin-3-yl)cyclohexanecarboxamide::CHEMBL378298::N-((S)-1-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}pyrrolidine-2,5-dion-3-yl)cyclohexanecarboxamide D(2) dopamine receptor Rattus norvegicus 2080 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50186244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50186244&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16739258 104070293 CHEMBL378298 ZINC36187830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376947 Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)C3CCCCC3)C2=O)CC1 InChI=1S/C25H35ClN4O3/c26-20-9-6-10-21(17-20)29-15-13-28(14-16-29)11-4-5-12-30-23(31)18-22(25(30)33)27-24(32)19-7-2-1-3-8-19/h6,9-10,17,19,22H,1-5,7-8,11-16,18H2,(H,27,32)/t22-/m0/s1 JQGSUXZAAKIPPD-QFIPXVFZSA-N 50206351 (S)-N-(1-(4-(4-(3-chlorophenyl)piperazin-1-yl)butyl)-2,5-dioxopyrrolidin-3-yl)cyclohexanecarboxamide::CHEMBL408589::N-((S)-1-{4-[4-(3-chlorophenyl)piperazin-1-yl]butyl}pyrrolidin-2,5-dion-3-yl)cyclohexanecarboxamide D(2) dopamine receptor Rattus norvegicus 2130 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11442899 104084485 CHEMBL408589 ZINC28819974 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376949 COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1 InChI=1S/C28H40N4O4/c1-36-25-7-3-2-6-24(25)31-14-12-30(13-15-31)10-4-5-11-32-27(34)19-23(28(32)35)29-26(33)18-22-17-20-8-9-21(22)16-20/h2-3,6-7,20-23H,4-5,8-19H2,1H3,(H,29,33)/t20?,21?,22?,23-/m0/s1 VDXRQLKUIDYFID-JVLTXYAPSA-N 50186243 2-(bicyclo[2.2.1]heptan-2-yl)-N-((S)-1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,5-dioxopyrrolidin-3-yl)acetamide::CHEMBL209007::N-((S)-1-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}pyrrolidin-2,5-dion-3-yl)-2-(bicyclo[2.2.1]heptan-2-yl)acetamide D(2) dopamine receptor Rattus norvegicus 880 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50186243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50186243&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44413025 104070292 CHEMBL209007 ZINC36187829 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376951 Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)C3CCCC3)C2=O)CC1 InChI=1S/C24H33ClN4O3/c25-19-8-5-9-20(16-19)28-14-12-27(13-15-28)10-3-4-11-29-22(30)17-21(24(29)32)26-23(31)18-6-1-2-7-18/h5,8-9,16,18,21H,1-4,6-7,10-15,17H2,(H,26,31)/t21-/m0/s1 DIGSPDFIECXXEM-NRFANRHFSA-N 50206344 CHEMBL398209::N-((S)-1-{4-[4-(3-chlorophenyl)piperazin-1-yl]butyl}pyrrolidin-2,5-dion-yl)cyclopentanecarboxamide D(2) dopamine receptor Rattus norvegicus 12450 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11408562 104084478 CHEMBL398209 ZINC28819938 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376952 COc1ccccc1N1CCN(CCCCN2C(=O)C[C@H](NC(=O)C34CC5CC(CC(C5)C3)C4)C2=O)CC1 InChI=1S/C30H42N4O4/c1-38-26-7-3-2-6-25(26)33-12-10-32(11-13-33)8-4-5-9-34-27(35)17-24(28(34)36)31-29(37)30-18-21-14-22(19-30)16-23(15-21)20-30/h2-3,6-7,21-24H,4-5,8-20H2,1H3,(H,31,37)/t21?,22?,23?,24-,30?/m0/s1 QJZONTFPLHEGKF-KAQSQBPVSA-N 50186236 Adamantane-1-carboxylic acid ((S)-1-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-2,5-dioxo-pyrrolidin-3-yl)-amide::CHEMBL208905::N-((S)-1-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}pyrrolidin-2,5-dion-yl)-1-adamantanecarboxamide::N-[(3S)-1-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-2,5-dioxopyrrolidin-3-yl]adamantane-1-carboxamide D(2) dopamine receptor Rattus norvegicus 1775 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50186236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50186236&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44413037 104070285 CHEMBL208905 ZINC36187827 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376956 Clc1cccc(c1)N1CCN(CCCC[C@@H]2CCCN2C(=O)C2CCCCC2)CC1 InChI=1S/C25H38ClN3O/c26-22-10-6-12-24(20-22)28-18-16-27(17-19-28)14-5-4-11-23-13-7-15-29(23)25(30)21-8-2-1-3-9-21/h6,10,12,20-21,23H,1-5,7-9,11,13-19H2/t23-/m1/s1 KKQKXXNCYFHKTJ-HSZRJFAPSA-N 50206345 1-(cyclohexylcarbonyl)-N-{4-[4-(3-chlorophenyl)piperazin-1-yl]butyl}-L-prolinamide::CHEMBL390659 D(2) dopamine receptor Rattus norvegicus 1050 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431018 104084479 CHEMBL390659 ZINC28820021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376957 Clc1cccc(c1)N1CCN(CCCCN2C(=O)CCC2=O)CC1 InChI=1S/C18H24ClN3O2/c19-15-4-3-5-16(14-15)21-12-10-20(11-13-21)8-1-2-9-22-17(23)6-7-18(22)24/h3-5,14H,1-2,6-13H2 VEXMLGRNFUUGTD-UHFFFAOYSA-N 50206349 1-(4-(4-(3-chlorophenyl)piperazin-1-yl)butyl)pyrrolidine-2,5-dione::CHEMBL398181 D(2) dopamine receptor Rattus norvegicus 7800 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431006 104084483 CHEMBL398181 ZINC13678541 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376958 COc1ccccc1N1CCN(CCCCN2C(=O)CCC2=O)CC1 InChI=1S/C19H27N3O3/c1-25-17-7-3-2-6-16(17)21-14-12-20(13-15-21)10-4-5-11-22-18(23)8-9-19(22)24/h2-3,6-7H,4-5,8-15H2,1H3 MQHOGPLXAXSQAJ-UHFFFAOYSA-N 50051166 1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrrolidine-2,5-dione::1-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-pyrrolidine-2,5-dione::CHEMBL279841 D(2) dopamine receptor Rattus norvegicus 490 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3994476 103948164 CHEMBL279841 ZINC02009671 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376961 Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)CC3CC4CCC3C4)C2=O)CC1 InChI=1S/C27H37ClN4O3/c28-22-4-3-5-23(17-22)31-12-10-30(11-13-31)8-1-2-9-32-26(34)18-24(27(32)35)29-25(33)16-21-15-19-6-7-20(21)14-19/h3-5,17,19-21,24H,1-2,6-16,18H2,(H,29,33)/t19?,20?,21?,24-/m0/s1 XHIDRVCCMYQHQX-HFHBMHTISA-N 50206350 CHEMBL390037::N-((S)-1-{4-[4-(3-chlorophenyl)piperazin-1-yl]butyl}pyrrolidin-2,5-dion-3-yl)-2-(bicyclo[2.2.1]heptan-2-yl)acetamide D(2) dopamine receptor Rattus norvegicus 776 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431013 104084484 CHEMBL390037 ZINC28819982 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376962 COc1ccccc1N1CCN(CCCC[C@@H]2CCCN2C(=O)C23CC4CC(CC(C4)C2)C3)CC1 InChI=1S/C30H45N3O2/c1-35-28-10-3-2-9-27(28)32-15-13-31(14-16-32)11-5-4-7-26-8-6-12-33(26)29(34)30-20-23-17-24(21-30)19-25(18-23)22-30/h2-3,9-10,23-26H,4-8,11-22H2,1H3/t23?,24?,25?,26-,30?/m1/s1 ZIRYRORSOPJCRQ-SKQAHVGISA-N 50206353 1-(adamantylcarbonyl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-L-prolinamide::CHEMBL232246 D(2) dopamine receptor Rattus norvegicus 1114 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206353&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431017 104084487 CHEMBL232246 ZINC28820018 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376970 Clc1cccc(c1)N1CCN(CCCCN2C(=O)C[C@H](NC(=O)C34CC5CC(CC(C5)C3)C4)C2=O)CC1 InChI=1S/C29H39ClN4O3/c30-23-4-3-5-24(15-23)33-10-8-32(9-11-33)6-1-2-7-34-26(35)16-25(27(34)36)31-28(37)29-17-20-12-21(18-29)14-22(13-20)19-29/h3-5,15,20-22,25H,1-2,6-14,16-19H2,(H,31,37)/t20?,21?,22?,25-,29?/m0/s1 PWFKOTHBUIUXGW-FADFPCINSA-N 50206354 CHEMBL231825::N-((S)-1-{4-[4-(3-chlorophenyl)piperazin-1-yl]butyl}pyrrolidin-2,5-dion-yl)-1-adamantanecarboxamide D(2) dopamine receptor Rattus norvegicus 21190 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206354&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11432502 104084488 CHEMBL231825 ZINC28819992 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50376971 Clc1cccc(c1)N1CCN(CCCC[C@@H]2CCCN2C(=O)CC2CC3CCC2C3)CC1 InChI=1S/C27H40ClN3O/c28-24-5-3-7-26(20-24)30-15-13-29(14-16-30)11-2-1-6-25-8-4-12-31(25)27(32)19-23-18-21-9-10-22(23)17-21/h3,5,7,20-23,25H,1-2,4,6,8-19H2/t21?,22?,23?,25-/m1/s1 PHXREEFTPPBZIF-HBSCBHPYSA-N 50206352 1-((bicyclo[2.2.1]heptan-2-yl)acetyl)-N-{4-[4-(3-chlorophenyl)piperazin-1-yl]butyl}-L-prolinamide::CHEMBL232247 D(2) dopamine receptor Rattus norvegicus 1550 ChEMBL 10.1016/j.bmc.2007.02.018 10.7270/Q20G3JTZ 17321139 Zajdel, P; Subra, G; Bojarski, AJ; Duszynska, B; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E; Pawlowski, M; Martinez, J University of Montpellier http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431019 104084486 CHEMBL232247 ZINC28820025 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50388845 CN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 InChI=1S/C18H19NO/c1-11-6-7-13-10-15-16-12(8-9-19(15)2)4-3-5-14(16)17(13)18(11)20/h3-7,15,20H,8-10H2,1-2H3/t15-/m1/s1 YGOZTDLAUVOPMF-OAHLLOKOSA-N 50036286 (R)-(-)-10-methyl-11-hydroxyaporphine::(R)-6,10-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL53510 D(2) dopamine receptor Rattus norvegicus 11500 ChEMBL 10.1016/j.bmcl.2007.05.057 10.7270/Q2ZG6RZ2 17543523 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3082625 103944104 CHEMBL53510 ZINC00006368 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50388856 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(CO)c(O)c-31 InChI=1S/C20H23NO2/c1-2-9-21-10-8-13-4-3-5-16-18(13)17(21)11-14-6-7-15(12-22)20(23)19(14)16/h3-7,17,22-23H,2,8-12H2,1H3/t17-/m1/s1 HPYHWVGULBZELQ-QGZVFWFLSA-N 50214521 (R)-10-hydroxymethyl-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL233567 D(2) dopamine receptor Rattus norvegicus 6060 ChEMBL 10.1016/j.bmcl.2007.05.057 10.7270/Q2ZG6RZ2 17543523 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214521&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44432812 104089499 CHEMBL233567 ZINC28823249 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50388858 CN1CCc2cccc-3c2[C@H]1Cc1ccc(CO)c(O)c-31 InChI=1S/C18H19NO2/c1-19-8-7-11-3-2-4-14-16(11)15(19)9-12-5-6-13(10-20)18(21)17(12)14/h2-6,15,20-21H,7-10H2,1H3/t15-/m1/s1 HATGKOHTAYTUSG-OAHLLOKOSA-N 50214523 (R)-10-hydroxymethyl-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL444368 D(2) dopamine receptor Rattus norvegicus 7000 ChEMBL 10.1016/j.bmcl.2007.05.057 10.7270/Q2ZG6RZ2 17543523 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214523&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23656544 104089501 CHEMBL444368 ZINC28823248 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50388860 COc1cc2CCN(C)[C@@H]3Cc4ccc(C)c(O)c4-c(c1)c23 InChI=1S/C19H21NO2/c1-11-4-5-12-9-16-17-13(6-7-20(16)2)8-14(22-3)10-15(17)18(12)19(11)21/h4-5,8,10,16,21H,6-7,9H2,1-3H3/t16-/m1/s1 UHYZEOGGPBAXJR-MRXNPFEDSA-N 50214522 (R)-2-methoxy-6,10-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL392447 D(2) dopamine receptor Rattus norvegicus 3760 ChEMBL 10.1016/j.bmcl.2007.05.057 10.7270/Q2ZG6RZ2 17543523 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23656545 104089500 CHEMBL392447 ZINC28823246 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50388861 CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1ccc(C)c(O)c-31 InChI=1S/C21H25NO2/c1-4-8-22-9-7-15-10-16(24-3)12-17-19(15)18(22)11-14-6-5-13(2)21(23)20(14)17/h5-6,10,12,18,23H,4,7-9,11H2,1-3H3/t18-/m1/s1 UBCLTXIFVDEQLA-GOSISDBHSA-N 50214520 (R)-2-methoxy-10-methyl-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL233566 D(2) dopamine receptor Rattus norvegicus 1350 ChEMBL 10.1016/j.bmcl.2007.05.057 10.7270/Q2ZG6RZ2 17543523 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44432811 104089498 CHEMBL233566 ZINC28823247 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382662 C[C@@H]1CN(CCN1CC[C@@H]1OCCc2cc(ccc12)C(N)=O)c1cccc2cc(F)ccc12 InChI=1S/C27H30FN3O2/c1-18-17-31(25-4-2-3-19-16-22(28)6-8-23(19)25)13-12-30(18)11-9-26-24-7-5-21(27(29)32)15-20(24)10-14-33-26/h2-8,15-16,18,26H,9-14,17H2,1H3,(H2,29,32)/t18-,26+/m1/s1 BVWYBVKUPUODDY-DWXRJYCRSA-N 50210633 (S)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide::CHEMBL391271 D(2) dopamine receptor Rattus norvegicus 71 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210633&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431532 104087120 CHEMBL391271 ZINC28821521 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382667 NC(=O)c1ccc2[C@H](CCN3CCN(CC3)c3ccc4cc(F)ccc4c3)OCCc2c1 InChI=1S/C26H28FN3O2/c27-22-4-1-19-17-23(5-2-18(19)16-22)30-12-10-29(11-13-30)9-7-25-24-6-3-21(26(28)31)15-20(24)8-14-32-25/h1-6,15-17,25H,7-14H2,(H2,28,31)/t25-/m0/s1 LSKWSFUPQIOHOG-VWLOTQADSA-N 50210636 (S)-1-(2-(4-(6-fluoronaphthalen-2-yl)piperazin-1-yl)ethyl)isochroman-6-carboxamide::CHEMBL234449 D(2) dopamine receptor Rattus norvegicus 704 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431535 104087123 CHEMBL234449 ZINC28821524 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382676 C[C@H]1CN(CCN1CC[C@H]1OCC2=CC(=CCC12)C(N)=O)c1cccc2cc(F)ccc12 InChI=1S/C26H30FN3O2/c1-17-15-30(24-4-2-3-18-14-21(27)6-8-22(18)24)12-11-29(17)10-9-25-23-7-5-19(26(28)31)13-20(23)16-32-25/h2-6,8,13-14,17,23,25H,7,9-12,15-16H2,1H3,(H2,28,31)/t17-,23?,25+/m0/s1 TZGHJRPUBWXMCC-PBGLVDLSSA-N 50210634 (1R)-1-(2-((S)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-1,3,7,7a-tetrahydroisobenzofuran-5-carboxamide::CHEMBL233212 D(2) dopamine receptor Rattus norvegicus 107 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210634&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431539 104087121 CHEMBL233212 ZINC28821528 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382677 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3c[nH]c4cc(F)ccc34)OCCc2c1 InChI=1S/C25H26FN3O2/c26-19-2-4-21-22(15-28-23(21)14-19)16-5-9-29(10-6-16)11-7-24-20-3-1-18(25(27)30)13-17(20)8-12-31-24/h1-5,13-15,24,28H,6-12H2,(H2,27,30) AYGLZYIWAZBQDC-UHFFFAOYSA-N 50145347 1-(2-(4-(6-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide::1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL83617 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9802187 104034188 CHEMBL83617 ZINC03976847 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382681 C[C@H]1CN(CCN1CC[C@H]1OCC2=CC(=CCC12)C(N)=O)c1cccc2cc(ccc12)C#N InChI=1S/C27H30N4O2/c1-18-16-31(25-4-2-3-20-13-19(15-28)5-7-23(20)25)12-11-30(18)10-9-26-24-8-6-21(27(29)32)14-22(24)17-33-26/h2-7,13-14,18,24,26H,8-12,16-17H2,1H3,(H2,29,32)/t18-,24?,26+/m0/s1 RNYOAQVTXKPTQL-XDYZAOKASA-N 50210640 (1R)-1-(2-((S)-4-(6-cyanonaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-1,3,7,7a-tetrahydroisobenzofuran-5-carboxamide::CHEMBL392780 D(2) dopamine receptor Rattus norvegicus 346 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210640&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431540 104087127 CHEMBL392780 ZINC28821529 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382682 NC(=O)c1ccc2[C@H](CCN3CCN(CC3)c3cccc4cc(ccc34)C#N)OCCc2c1 InChI=1S/C27H28N4O2/c28-18-19-4-6-23-20(16-19)2-1-3-25(23)31-13-11-30(12-14-31)10-8-26-24-7-5-22(27(29)32)17-21(24)9-15-33-26/h1-7,16-17,26H,8-15H2,(H2,29,32)/t26-/m0/s1 IRSJJJFRMIQSOE-SANMLTNESA-N 50210635 (S)-1-(2-(4-(6-cyanonaphthalen-1-yl)piperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide::CHEMBL391273 D(2) dopamine receptor Rattus norvegicus 88 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210635&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431537 104087122 CHEMBL391273 ZINC28821526 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382684 C[C@@H]1CN(CCN1CC[C@H]1OCCc2cc(ccc12)C(N)=O)c1cccc2cc(F)ccc12 InChI=1S/C27H30FN3O2/c1-18-17-31(25-4-2-3-19-16-22(28)6-8-23(19)25)13-12-30(18)11-9-26-24-7-5-21(27(29)32)15-20(24)10-14-33-26/h2-8,15-16,18,26H,9-14,17H2,1H3,(H2,29,32)/t18-,26-/m1/s1 BVWYBVKUPUODDY-WXTAPIANSA-N 50210639 (R)-1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide::CHEMBL234448 D(2) dopamine receptor Rattus norvegicus 78 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210639&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431533 104087126 CHEMBL234448 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382696 C[C@@H]1CN(CCN1CCC1OCCc2cc(ccc12)C(N)=O)c1cccc2cc(F)ccc12 InChI=1S/C27H30FN3O2/c1-18-17-31(25-4-2-3-19-16-22(28)6-8-23(19)25)13-12-30(18)11-9-26-24-7-5-21(27(29)32)15-20(24)10-14-33-26/h2-8,15-16,18,26H,9-14,17H2,1H3,(H2,29,32)/t18-,26?/m1/s1 BVWYBVKUPUODDY-QOBPCVTDSA-N 50210638 1-(2-((R)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide::CHEMBL234447 D(2) dopamine receptor Rattus norvegicus 4.7 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431531 104087125 CHEMBL234447 ZINC28821522 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382702 C[C@H]1CN(CCN1CC[C@@H]1OCCc2cc(ccc12)C(N)=O)c1ccc2cc(F)ccc2c1 InChI=1S/C27H30FN3O2/c1-18-17-31(24-6-3-19-15-23(28)5-2-20(19)16-24)12-11-30(18)10-8-26-25-7-4-22(27(29)32)14-21(25)9-13-33-26/h2-7,14-16,18,26H,8-13,17H2,1H3,(H2,29,32)/t18-,26-/m0/s1 RRWISUYOSRHAFZ-QYBDOPJKSA-N 50210641 (S)-1-(2-((S)-4-(6-fluoronaphthalen-2-yl)-2-methylpiperazin-1-yl)ethyl)isochroman-6-carboxamide::CHEMBL391272 D(2) dopamine receptor Rattus norvegicus 1170 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210641&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431534 104087128 CHEMBL391272 ZINC28821523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382716 C[C@H]1CN(CCN1CC[C@@H]1OCCc2cc(ccc12)C(N)=O)c1cccc2cc(ccc12)C#N InChI=1S/C28H30N4O2/c1-19-18-32(26-4-2-3-21-15-20(17-29)5-7-24(21)26)13-12-31(19)11-9-27-25-8-6-23(28(30)33)16-22(25)10-14-34-27/h2-8,15-16,19,27H,9-14,18H2,1H3,(H2,30,33)/t19-,27-/m0/s1 WNCRJQLQHVFPBO-PPHZAIPVSA-N 50210642 (S)-1-(2-((S)-4-(6-cyanonaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide::CHEMBL233210 D(2) dopamine receptor Rattus norvegicus 287 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431536 104087129 CHEMBL233210 ZINC28821525 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50382723 C[C@H]1CN(CCN1CC[C@@H]1OCC2=CC(=CCC12)C(N)=O)c1cccc2cc(F)ccc12 InChI=1S/C26H30FN3O2/c1-17-15-30(24-4-2-3-18-14-21(27)6-8-22(18)24)12-11-29(17)10-9-25-23-7-5-19(26(28)31)13-20(23)16-32-25/h2-6,8,13-14,17,23,25H,7,9-12,15-16H2,1H3,(H2,28,31)/t17-,23?,25-/m0/s1 TZGHJRPUBWXMCC-DQNHKJGCSA-N 50210637 (1S)-1-(2-((S)-4-(6-fluoronaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-1,3,7,7a-tetrahydroisobenzofuran-5-carboxamide::CHEMBL233211 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1016/j.bmcl.2007.03.101 10.7270/Q20V8CG3 17434731 Bueno, AB; Gilmore, J; Boot, J; Broadmore, R; Cooper, J; Findlay, J; Hayhurst, L; Marcos, A; Montero, C; Mitchell, S; Timms, G; Tomlinson, R; Wallace, L; Walton, L Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50210637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50210637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44431538 104087124 CHEMBL233211 ZINC28821527 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396677 CC(=O)Nc1ccc(cc1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cc(cc(c2)C(F)(F)F)C#N)CC1 InChI=1S/C28H34F3N5O3S/c1-20(37)33-24-6-8-27(9-7-24)40(38,39)34-25-4-2-21(3-5-25)10-11-35-12-14-36(15-13-35)26-17-22(19-32)16-23(18-26)28(29,30)31/h6-9,16-18,21,25,34H,2-5,10-15H2,1H3,(H,33,37)/t21-,25- LXMMBRNGXUZPDD-OKDASEJXSA-N 50219935 CHEMBL392528::N-[4-(4-{2-[4-(3-cyano-5-trifluoromethyl-phenyl)-piperazin-1-yl]-ethyl}-cyclohexylsulfamoyl)-phenyl]-acetamide D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219935&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435095 104093058 CHEMBL392528 ZINC28826608 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396678 Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3cccnc3)CC2)c1Cl InChI=1S/C23H30Cl2N4O2S/c24-21-4-1-5-22(23(21)25)29-15-13-28(14-16-29)12-10-18-6-8-19(9-7-18)27-32(30,31)20-3-2-11-26-17-20/h1-5,11,17-19,27H,6-10,12-16H2/t18-,19- DLCUNIPVNVPKEI-WGSAOQKQSA-N 50219939 CHEMBL240693::N-((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)pyridine-3-sulfonamide D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24180454 104093062 CHEMBL240693 ZINC28826616 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396679 FC(F)(F)c1cc(cc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NS(=O)(=O)c2ccc(Br)cc2)CC1)C#N InChI=1S/C26H30BrF3N4O2S/c27-22-3-7-25(8-4-22)37(35,36)32-23-5-1-19(2-6-23)9-10-33-11-13-34(14-12-33)24-16-20(18-31)15-21(17-24)26(28,29)30/h3-4,7-8,15-17,19,23,32H,1-2,5-6,9-14H2/t19-,23- FCSNJXPPXJWFER-UILWBTOOSA-N 50219936 4-bromo-N-((1r,4r)-4-(2-(4-(3-cyano-5-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)cyclohexyl)benzenesulfonamide::CHEMBL239846 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219936&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435090 104093059 CHEMBL239846 ZINC28826600 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396680 FC(F)(F)c1cccc(NC2CCN(CC[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3ccc(Cl)cc3)CC2)c1 InChI=1S/C26H33ClF3N3O2S/c27-21-6-10-25(11-7-21)36(34,35)32-23-8-4-19(5-9-23)12-15-33-16-13-22(14-17-33)31-24-3-1-2-20(18-24)26(28,29)30/h1-3,6-7,10-11,18-19,22-23,31-32H,4-5,8-9,12-17H2/t19-,23- OUSKSBFRBAHODU-UILWBTOOSA-N 50219937 4-chloro-N-((1r,4r)-4-(2-(4-(3-(trifluoromethyl)phenylamino)piperidin-1-yl)ethyl)cyclohexyl)benzenesulfonamide::CHEMBL393556 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219937&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435089 104093060 CHEMBL393556 ZINC03988964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396682 FC(F)(F)c1cccc(OC2CCN(CC[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3cccnc3)CC2)c1 InChI=1S/C25H32F3N3O3S/c26-25(27,28)20-3-1-4-23(17-20)34-22-11-15-31(16-12-22)14-10-19-6-8-21(9-7-19)30-35(32,33)24-5-2-13-29-18-24/h1-5,13,17-19,21-22,30H,6-12,14-16H2/t19-,21- YPTJILAMYFGVSH-XUTJKUGGSA-N 50219938 CHEMBL391699::N-((1r,4r)-4-(2-(4-(3-(trifluoromethyl)phenoxy)piperidin-1-yl)ethyl)cyclohexyl)pyridine-3-sulfonamide D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219938&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435099 104093061 CHEMBL391699 ZINC03988969 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396685 Cc1ccc(cn1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cc(cc(c2)C(F)(F)F)C#N)CC1 InChI=1S/C26H32F3N5O2S/c1-19-2-7-25(18-31-19)37(35,36)32-23-5-3-20(4-6-23)8-9-33-10-12-34(13-11-33)24-15-21(17-30)14-22(16-24)26(27,28)29/h2,7,14-16,18,20,23,32H,3-6,8-13H2,1H3/t20-,23- PCIZAOBILWCZLZ-JKIUYZKVSA-N 50219941 CHEMBL240909::N-((1r,4r)-4-(2-(4-(3-cyano-5-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)cyclohexyl)-6-methylpyridine-3-sulfonamide D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435101 104093064 CHEMBL240909 ZINC28826619 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396691 FC(F)(F)c1cccc(CC2CCN(CC[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3ccc(Cl)cc3)CC2)c1 InChI=1S/C27H34ClF3N2O2S/c28-24-6-10-26(11-7-24)36(34,35)32-25-8-4-20(5-9-25)12-15-33-16-13-21(14-17-33)18-22-2-1-3-23(19-22)27(29,30)31/h1-3,6-7,10-11,19-21,25,32H,4-5,8-9,12-18H2/t20-,25- KUPGAPXCPCXKDD-WBANQOEISA-N 50219934 CHEMBL399833::N-((1r,4r)-4-(2-(4-(3-(trifluoromethyl)benzyl)piperidin-1-yl)ethyl)cyclohexyl)-4-chlorobenzenesulfonamide D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219934&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435088 104093057 CHEMBL399833 ZINC28826599 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396694 COc1ccc(cc1OC)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(c2)C#N)CC1 InChI=1S/C27H36N4O4S/c1-34-26-11-10-25(19-27(26)35-2)36(32,33)29-23-8-6-21(7-9-23)12-13-30-14-16-31(17-15-30)24-5-3-4-22(18-24)20-28/h3-5,10-11,18-19,21,23,29H,6-9,12-17H2,1-2H3/t21-,23- QMBLUFIVEKJLQY-AFARHQOCSA-N 50219947 CHEMBL429093::N-((1r,4r)-4-(2-(4-(3-cyanophenyl)piperazin-1-yl)ethyl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide D(2) dopamine receptor Rattus norvegicus 57 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435092 104093070 CHEMBL429093 ZINC28826602 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396695 FC(F)(F)c1cc(cc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NS(=O)(=O)c2ccc3NC(=O)CCc3c2)CC1)C#N InChI=1S/C29H34F3N5O3S/c30-29(31,32)23-15-21(19-33)16-25(18-23)37-13-11-36(12-14-37)10-9-20-1-4-24(5-2-20)35-41(39,40)26-6-7-27-22(17-26)3-8-28(38)34-27/h6-7,15-18,20,24,35H,1-5,8-14H2,(H,34,38)/t20-,24- HVFQVLBUJHAZFN-LSNLESRRSA-N 50219945 CHEMBL240273::N-((1r,4r)-4-(2-(4-(3-cyano-5-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)cyclohexyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonamide D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435097 104093068 CHEMBL240273 ZINC28826611 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396698 Fc1ccc(cc1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)Nc2cc(Cl)ccc2Cl)CC1 InChI=1S/C25H32Cl2FN3O2S/c26-19-3-10-24(27)25(17-19)29-21-12-15-31(16-13-21)14-11-18-1-6-22(7-2-18)30-34(32,33)23-8-4-20(28)5-9-23/h3-5,8-10,17-18,21-22,29-30H,1-2,6-7,11-16H2/t18-,22- NDTPECCQNUXAEC-LBZQVFOQSA-N 50219942 CHEMBL240051::N-((1r,4r)-4-(2-(4-(2,5-dichlorophenylamino)piperidin-1-yl)ethyl)cyclohexyl)-4-fluorobenzenesulfonamide D(2) dopamine receptor Rattus norvegicus 9 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435087 104093065 CHEMBL240051 ZINC28826598 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396699 FC(F)(F)c1cccc(OC2CCN(CC[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3ccc4OCC(=O)Nc4c3)CC2)c1 InChI=1S/C28H34F3N3O5S/c29-28(30,31)20-2-1-3-23(16-20)39-22-11-14-34(15-12-22)13-10-19-4-6-21(7-5-19)33-40(36,37)24-8-9-26-25(17-24)32-27(35)18-38-26/h1-3,8-9,16-17,19,21-22,33H,4-7,10-15,18H2,(H,32,35)/t19-,21- JRHGAKDMCLLJTM-XUTJKUGGSA-N 50219949 3-oxo-N-((1r,4r)-4-(2-(4-(3-(trifluoromethyl)phenoxy)piperidin-1-yl)ethyl)cyclohexyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-sulfonamide::CHEMBL240480 D(2) dopamine receptor Rattus norvegicus 5.3 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219949&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435098 104093072 CHEMBL240480 ZINC28826613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396700 COc1ccc(cc1)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccc(Br)cc2OC)CC1 InChI=1S/C26H36BrN3O4S/c1-33-23-8-10-24(11-9-23)35(31,32)28-22-6-3-20(4-7-22)13-14-29-15-17-30(18-16-29)25-12-5-21(27)19-26(25)34-2/h5,8-12,19-20,22,28H,3-4,6-7,13-18H2,1-2H3/t20-,22- OWSHDISQJVVMQC-AQYVVDRMSA-N 50219944 CHEMBL239847::N-((1r,4r)-4-(2-(4-(4-bromo-2-methoxyphenyl)piperazin-1-yl)ethyl)cyclohexyl)-4-methoxybenzenesulfonamide D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219944&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435091 104093067 CHEMBL239847 ZINC28826601 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396701 FC(F)(F)c1cccc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NS(=O)(=O)c2cccnc2)CC1 InChI=1S/C24H31F3N4O2S/c25-24(26,27)20-3-1-4-22(17-20)31-15-13-30(14-16-31)12-10-19-6-8-21(9-7-19)29-34(32,33)23-5-2-11-28-18-23/h1-5,11,17-19,21,29H,6-10,12-16H2/t19-,21- KYNADVPWOIATEI-XUTJKUGGSA-N 50219946 CHEMBL391700::N-((1r,4r)-4-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)cyclohexyl)pyridine-3-sulfonamide D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435100 104093069 CHEMBL391700 ZINC03988968 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396702 FC(F)(F)c1cccc(CC2CCN(CC[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3ccc(cc3)-n3cccn3)CC2)c1 InChI=1S/C30H37F3N4O2S/c31-30(32,33)26-4-1-3-25(22-26)21-24-14-19-36(20-15-24)18-13-23-5-7-27(8-6-23)35-40(38,39)29-11-9-28(10-12-29)37-17-2-16-34-37/h1-4,9-12,16-17,22-24,27,35H,5-8,13-15,18-21H2/t23-,27- UYHCIKJLSMEARZ-JIBACQESSA-N 50219940 CHEMBL240271::N-((1r,4r)-4-(2-(4-(3-(trifluoromethyl)benzyl)piperidin-1-yl)ethyl)cyclohexyl)-4-(1H-pyrazol-1-yl)benzenesulfonamide D(2) dopamine receptor Rattus norvegicus 4.3 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219940&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435096 104093063 CHEMBL240271 ZINC28826609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396703 FC(F)(F)c1cc(cc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NS(=O)(=O)c2cccc(c2)C#N)CC1)C#N InChI=1S/C27H30F3N5O2S/c28-27(29,30)23-14-22(19-32)15-25(17-23)35-12-10-34(11-13-35)9-8-20-4-6-24(7-5-20)33-38(36,37)26-3-1-2-21(16-26)18-31/h1-3,14-17,20,24,33H,4-13H2/t20-,24- SHWRVFAKOGFBCZ-LSNLESRRSA-N 50219950 3-cyano-N-((1r,4r)-4-(2-(4-(3-cyano-5-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)cyclohexyl)benzenesulfonamide::CHEMBL392527 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435094 104093073 CHEMBL392527 ZINC28826604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396705 FC(F)(F)c1cc(cc(c1)N1CCN(CC[C@H]2CC[C@@H](CC2)NS(=O)(=O)c2cccnc2)CC1)C#N InChI=1S/C25H30F3N5O2S/c26-25(27,28)21-14-20(17-29)15-23(16-21)33-12-10-32(11-13-33)9-7-19-3-5-22(6-4-19)31-36(34,35)24-2-1-8-30-18-24/h1-2,8,14-16,18-19,22,31H,3-7,9-13H2/t19-,22- FZTKOLKXELORMS-XYWHTSSQSA-N 50219943 CHEMBL428910::N-((1r,4r)-4-(2-(4-(3-cyano-5-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)cyclohexyl)pyridine-3-sulfonamide D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219943&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10142798 104093066 CHEMBL428910 ZINC28826660 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50396709 FC(F)(F)c1cccc(CC2CCN(CC[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3cc4ccccc4s3)CC2)c1 InChI=1S/C29H35F3N2O2S2/c30-29(31,32)25-6-3-4-23(19-25)18-22-13-16-34(17-14-22)15-12-21-8-10-26(11-9-21)33-38(35,36)28-20-24-5-1-2-7-27(24)37-28/h1-7,19-22,26,33H,8-18H2/t21-,26- QWEKXOVUJZFIHF-WVPZODRTSA-N 50219948 CHEMBL236407::N-((1r,4r)-4-(2-(4-(3-(trifluoromethyl)benzyl)piperidin-1-yl)ethyl)cyclohexyl)benzo[b]thiophene-2-sulfonamide D(2) dopamine receptor Rattus norvegicus 91 ChEMBL 10.1016/j.bmcl.2007.08.015 10.7270/Q22F7N5G 17720494 Agai-Csongor, E; Nogradi, K; Galambos, J; Vago, I; Bielik, A; Magdo, I; Ignacz-Szendrei, G; Keseru, GM; Greiner, I; Laszlovszky, I; Schmidt, E; Kiss, B; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Domany, G Gedeon Richter Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50219948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50219948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44435102 104093071 CHEMBL236407 ZINC28826620 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50403906 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1016/j.ejmech.2015.06.039 10.7270/Q25M67H8 26164842 Matera, C; Pucci, L; Fiorentini, C; Fucile, S; Missale, C; Grazioso, G; Clementi, F; Zoli, M; De Amici, M; Gotti, C; Dallanoce, C Universit£ degli Studi di Milano http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50403907 [Br-].CN1CCC[C@H]1c1ccc[n+](CCCCCCCCCCCCNCC2CCc3ccc(O)cc3O2)c1 InChI=1S/C32H49N3O2.BrH/c1-34-21-13-15-31(34)28-14-12-23-35(26-28)22-11-9-7-5-3-2-4-6-8-10-20-33-25-30-19-17-27-16-18-29(36)24-32(27)37-30;/h12,14,16,18,23-24,26,30-31,33H,2-11,13,15,17,19-22,25H2,1H3;1H/t30?,31-;/m0./s1 ZBYQPTKAJYPXPW-VBZSYHMBSA-N 50116300 CHEMBL3612361 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1016/j.ejmech.2015.06.039 10.7270/Q25M67H8 26164842 Matera, C; Pucci, L; Fiorentini, C; Fucile, S; Missale, C; Grazioso, G; Clementi, F; Zoli, M; De Amici, M; Gotti, C; Dallanoce, C Universit£ degli Studi di Milano http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116300&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122188159 319494197 CHEMBL3612361 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50403908 [Br-].CN1CCC[C@H]1c1ccc[n+](CCCCCCCCCCNCC2CCc3ccc(O)cc3O2)c1 InChI=1S/C30H45N3O2.BrH/c1-32-19-11-13-29(32)26-12-10-21-33(24-26)20-9-7-5-3-2-4-6-8-18-31-23-28-17-15-25-14-16-27(34)22-30(25)35-28;/h10,12,14,16,21-22,24,28-29,31H,2-9,11,13,15,17-20,23H2,1H3;1H/t28?,29-;/m0./s1 GTIPANYRNCQASG-ARHHNASGSA-N 50116299 CHEMBL3612360 D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1016/j.ejmech.2015.06.039 10.7270/Q25M67H8 26164842 Matera, C; Pucci, L; Fiorentini, C; Fucile, S; Missale, C; Grazioso, G; Clementi, F; Zoli, M; De Amici, M; Gotti, C; Dallanoce, C Universit£ degli Studi di Milano http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122188157 319494196 CHEMBL3612360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50403909 [Br-].CN1CCC[C@H]1c1ccc[n+](CCCCCCNCC2CCc3ccc(O)cc3O2)c1 InChI=1S/C26H37N3O2.BrH/c1-28-15-7-9-25(28)22-8-6-17-29(20-22)16-5-3-2-4-14-27-19-24-13-11-21-10-12-23(30)18-26(21)31-24;/h6,8,10,12,17-18,20,24-25,27H,2-5,7,9,11,13-16,19H2,1H3;1H/t24?,25-;/m0./s1 BNPZQIJALSSGBJ-MRUATQDUSA-N 50116199 CHEMBL3612359 D(2) dopamine receptor Rattus norvegicus 97 ChEMBL 10.1016/j.ejmech.2015.06.039 10.7270/Q25M67H8 26164842 Matera, C; Pucci, L; Fiorentini, C; Fucile, S; Missale, C; Grazioso, G; Clementi, F; Zoli, M; De Amici, M; Gotti, C; Dallanoce, C Universit£ degli Studi di Milano http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116199 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116199&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122188155 104009999 CHEMBL3612359 ZINC13445208 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50403910 [Br-].CN1CCC[C@H]1c1ccc[n+](CCCCCNCC2CCc3ccc(O)cc3O2)c1 InChI=1S/C25H35N3O2.BrH/c1-27-14-6-8-24(27)21-7-5-16-28(19-21)15-4-2-3-13-26-18-23-12-10-20-9-11-22(29)17-25(20)30-23;/h5,7,9,11,16-17,19,23-24,26H,2-4,6,8,10,12-15,18H2,1H3;1H/t23?,24-;/m0./s1 RMUPCYORZHHTBX-ZAPAOSNUSA-N 50116197 CHEMBL3612358 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1016/j.ejmech.2015.06.039 10.7270/Q25M67H8 26164842 Matera, C; Pucci, L; Fiorentini, C; Fucile, S; Missale, C; Grazioso, G; Clementi, F; Zoli, M; De Amici, M; Gotti, C; Dallanoce, C Universit£ degli Studi di Milano http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116197 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116197&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122188153 104009997 CHEMBL3612358 ZINC13445205 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50403911 CCCCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C16H25NO2/c1-2-3-4-5-10-17-12-15-9-7-13-6-8-14(18)11-16(13)19-15/h6,8,11,15,17-18H,2-5,7,9-10,12H2,1H3 QNPXMHDZEWNMNS-UHFFFAOYSA-N 50061679 2-Hexylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135222 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1016/j.ejmech.2015.06.039 10.7270/Q25M67H8 26164842 Matera, C; Pucci, L; Fiorentini, C; Fucile, S; Missale, C; Grazioso, G; Clementi, F; Zoli, M; De Amici, M; Gotti, C; Dallanoce, C Universit£ degli Studi di Milano http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10220913 103957229 CHEMBL135222 ZINC03959251 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50403912 CCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C13H19NO2/c1-2-7-14-9-12-6-4-10-3-5-11(15)8-13(10)16-12/h3,5,8,12,14-15H,2,4,6-7,9H2,1H3 PEHTUJKNDCNRDK-UHFFFAOYSA-N 50061652 2-Propylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135636 D(2) dopamine receptor Rattus norvegicus 49 ChEMBL 10.1016/j.ejmech.2015.06.039 10.7270/Q25M67H8 26164842 Matera, C; Pucci, L; Fiorentini, C; Fucile, S; Missale, C; Grazioso, G; Clementi, F; Zoli, M; De Amici, M; Gotti, C; Dallanoce, C Universit£ degli Studi di Milano http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061652&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10513189 103957202 CHEMBL135636 ZINC03959253 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412737 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 202 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412739 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccccc1)C1CCc2nc(N)sc2C1 InChI=1S/C28H37N5S/c1-2-14-32(25-12-13-26-27(21-25)34-28(29)30-26)18-15-31-16-19-33(20-17-31)24-10-8-23(9-11-24)22-6-4-3-5-7-22/h3-11,25H,2,12-21H2,1H3,(H2,29,30) YDLWLYDTYNHXBM-UHFFFAOYSA-N 50261383 (-)-N6-(2-(4-(Biphenyl-4-yl)piperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL467540 D(2) dopamine receptor Rattus norvegicus 264 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24936081 104110494 CHEMBL467540 ZINC40876250 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412740 CCCN(CCN1CCN(CC1)c1cccc(Cl)c1Cl)C1CCc2nc(N)sc2C1 InChI=1S/C22H31Cl2N5S/c1-2-8-28(16-6-7-18-20(15-16)30-22(25)26-18)12-9-27-10-13-29(14-11-27)19-5-3-4-17(23)21(19)24/h3-5,16H,2,6-15H2,1H3,(H2,25,26) MTSRJJUOIYINNP-UHFFFAOYSA-N 50261279 (+)-N6-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::(-)-N6-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL468017::D-219::N6-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiaxole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 56.8 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866114 104110452 CHEMBL468017 ZINC40879460 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412741 CCCN(CCN1CCN(CC1)c1cccc(Cl)c1Cl)C1CCc2nc(N)sc2C1 InChI=1S/C22H31Cl2N5S/c1-2-8-28(16-6-7-18-20(15-16)30-22(25)26-18)12-9-27-10-13-29(14-11-27)19-5-3-4-17(23)21(19)24/h3-5,16H,2,6-15H2,1H3,(H2,25,26) MTSRJJUOIYINNP-UHFFFAOYSA-N 50261279 (+)-N6-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::(-)-N6-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL468017::D-219::N6-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiaxole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 56.8 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866114 104110452 CHEMBL468017 ZINC40879460 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412742 CCCN(CCN1CCN(CC1)c1ccccc1OC)C1CCc2nc(N)sc2C1 InChI=1S/C23H35N5OS/c1-3-10-27(18-8-9-19-22(17-18)30-23(24)25-19)14-11-26-12-15-28(16-13-26)20-6-4-5-7-21(20)29-2/h4-7,18H,3,8-17H2,1-2H3,(H2,24,25) WIZIUHWXARABLD-UHFFFAOYSA-N 50261278 (+)-N6-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::(-)-N6-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL468016::D-210::N6-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiaxole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 288 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866614 104110451 CHEMBL468016 ZINC40879452 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412743 CCCN(CCN1CCN(CC1)c1ccccc1OC)C1CCc2nc(N)sc2C1 InChI=1S/C23H35N5OS/c1-3-10-27(18-8-9-19-22(17-18)30-23(24)25-19)14-11-26-12-15-28(16-13-26)20-6-4-5-7-21(20)29-2/h4-7,18H,3,8-17H2,1-2H3,(H2,24,25) WIZIUHWXARABLD-UHFFFAOYSA-N 50261278 (+)-N6-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::(-)-N6-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL468016::D-210::N6-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiaxole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 288 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866614 104110451 CHEMBL468016 ZINC40879452 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412744 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2nc(N)sc2C1 InChI=1S/C22H33N5S/c1-2-10-26(19-8-9-20-21(17-19)28-22(23)24-20)14-11-25-12-15-27(16-13-25)18-6-4-3-5-7-18/h3-7,19H,2,8-17H2,1H3,(H2,23,24) QXKRKYHYAGPGAN-UHFFFAOYSA-N 50261277 (+)-N6-(2-(4-Phenylpiperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::(-)-N6-(2-(4-Phenylpiperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL468015::N6-(2-(4-Phenylpiperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 243 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44593628 104110450 CHEMBL468015 ZINC40848964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412745 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2nc(N)sc2C1 InChI=1S/C22H33N5S/c1-2-10-26(19-8-9-20-21(17-19)28-22(23)24-20)14-11-25-12-15-27(16-13-25)18-6-4-3-5-7-18/h3-7,19H,2,8-17H2,1H3,(H2,23,24) QXKRKYHYAGPGAN-UHFFFAOYSA-N 50261277 (+)-N6-(2-(4-Phenylpiperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::(-)-N6-(2-(4-Phenylpiperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL468015::N6-(2-(4-Phenylpiperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 243 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44593628 104110450 CHEMBL468015 ZINC40848964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412746 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2cn[nH]c2C1 InChI=1S/C22H33N5/c1-2-10-26(21-9-8-19-18-23-24-22(19)17-21)14-11-25-12-15-27(16-13-25)20-6-4-3-5-7-20/h3-7,18,21H,2,8-17H2,1H3,(H,23,24) MNBXINPRAIZJNI-UHFFFAOYSA-N 50261336 CHEMBL467768::[2-(4-Phenylpiperazin-1-yl)ethyl]propyl(4,5,6,7-tetrahydro-2H-indazol-6-yl]amine D(2) dopamine receptor Rattus norvegicus 2570 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866296 104110483 CHEMBL467768 ZINC40877201 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412747 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2nn[se]c2C1 InChI=1S/C21H31N5Se/c1-2-10-25(19-8-9-20-21(17-19)27-23-22-20)14-11-24-12-15-26(16-13-24)18-6-4-3-5-7-18/h3-7,19H,2,8-17H2,1H3 PFIKDGAKWFWZIM-UHFFFAOYSA-N 50261335 CHEMBL467767::D-190::[2-(4-Phenylpiperazin-1-yl)ethyl]propyl(4,5,6,7-tetrahydrobenzo[1,2,3]selenadiazol-6-yl)amine D(2) dopamine receptor Rattus norvegicus 189 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261335&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866294 104110482 CHEMBL467767 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412748 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2nnsc2C1 InChI=1S/C21H31N5S/c1-2-10-25(19-8-9-20-21(17-19)27-23-22-20)14-11-24-12-15-26(16-13-24)18-6-4-3-5-7-18/h3-7,19H,2,8-17H2,1H3 JICSOUQQDNPUEL-UHFFFAOYSA-N 50261334 CHEMBL466561::[2-(4-Phenylpiperazin-1-yl)ethyl]propyl(4,5,6,7-tetrahydrobenzo[1,2,3]thiadiazol-6-yl)amine D(2) dopamine receptor Rattus norvegicus 746 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866292 104110481 CHEMBL466561 ZINC40880287 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412749 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2nocc2C1 InChI=1S/C22H32N4O/c1-2-10-25(21-8-9-22-19(17-21)18-27-23-22)14-11-24-12-15-26(16-13-24)20-6-4-3-5-7-20/h3-7,18,21H,2,8-17H2,1H3 FVLVETKUEQQGET-UHFFFAOYSA-N 50261306 CHEMBL469182::D-192::[2-(4-Phenylpiperazin-1-yl)ethyl]propyl(4,5,6,7-tetrahydrobenzo[c]isoxazol-5-yl)amine D(2) dopamine receptor Rattus norvegicus 813 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261306&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866118 104110468 CHEMBL469182 ZINC40895648 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412750 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2oncc2C1 InChI=1S/C22H32N4O/c1-2-10-25(21-8-9-22-19(17-21)18-23-27-22)14-11-24-12-15-26(16-13-24)20-6-4-3-5-7-20/h3-7,18,21H,2,8-17H2,1H3 SYVXHALPVYBOLF-UHFFFAOYSA-N 50261305 CHEMBL469181::D-193::[2-(4-Phenylpiperazin-1-yl)ethyl]propyl(4,5,6,7-tetrahydrobenzo[d]isoxazol-5-yl)amine D(2) dopamine receptor Rattus norvegicus 915 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261305&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866290 104110467 CHEMBL469181 ZINC40895642 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412751 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2[nH]ncc2C1 InChI=1S/C22H33N5/c1-2-10-26(21-8-9-22-19(17-21)18-23-24-22)14-11-25-12-15-27(16-13-25)20-6-4-3-5-7-20/h3-7,18,21H,2,8-17H2,1H3,(H,23,24) LHOJVHKKDRWEEV-UHFFFAOYSA-N 50261304 CHEMBL468834::D-189::N-(2-(4-Phenylpiperazin-1-yl)ethyl)-N-propyl-4,5,6,7-tetrahydro-1H-indazol-5-amine D(2) dopamine receptor Rattus norvegicus 1835 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261304&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866288 104110466 CHEMBL468834 ZINC40893898 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411687 CCCCOc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C21H25NO3/c1-3-4-9-25-15-10-14-7-8-22(2)17-11-13-5-6-18(23)21(24)20(13)16(12-15)19(14)17/h5-6,10,12,17,23-24H,3-4,7-9,11H2,1-2H3/t17-/m1/s1 BYGOBYFAXDOLTN-QGZVFWFLSA-N 50251327 (R)-2-Butoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL449461 D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567594 104104496 CHEMBL449461 ZINC40835949 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411688 CN1CCc2cc(OCCO)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO4/c1-20-5-4-12-8-13(24-7-6-21)10-14-17(12)15(20)9-11-2-3-16(22)19(23)18(11)14/h2-3,8,10,15,21-23H,4-7,9H2,1H3/t15-/m1/s1 MLSWBRKIYGJEGT-OAHLLOKOSA-N 50251328 CHEMBL457275::[R-(-)-Apomorphine-2-yl]-(2'-hydroxy-ethyl)ether D(2) dopamine receptor Rattus norvegicus 315 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251328&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567595 104104497 CHEMBL457275 ZINC40380136 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411689 CN1CCc2cc(OCCOCCO)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C21H25NO5/c1-22-5-4-14-10-15(27-9-8-26-7-6-23)12-16-19(14)17(22)11-13-2-3-18(24)21(25)20(13)16/h2-3,10,12,17,23-25H,4-9,11H2,1H3/t17-/m1/s1 LUIRUBNQVJTQKP-QGZVFWFLSA-N 50251329 2-{[R-(-)-Apomorphine-2'-oxy]ethoxy}-ethanol::CHEMBL516151 D(2) dopamine receptor Rattus norvegicus 939 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251329&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567596 104104498 CHEMBL516151 ZINC40848455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411691 CCCOc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C20H23NO3/c1-3-8-24-14-9-13-6-7-21(2)16-10-12-4-5-17(22)20(23)19(12)15(11-14)18(13)16/h4-5,9,11,16,22-23H,3,6-8,10H2,1-2H3/t16-/m1/s1 BCZNYILKVXTJOI-MRXNPFEDSA-N 50251321 (R)-6-Methyl-2-propoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL517491 D(2) dopamine receptor Rattus norvegicus 75 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567588 104104495 CHEMBL517491 ZINC40877998 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411692 CCOc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C19H21NO3/c1-3-23-13-8-12-6-7-20(2)15-9-11-4-5-16(21)19(22)18(11)14(10-13)17(12)15/h4-5,8,10,15,21-22H,3,6-7,9H2,1-2H3/t15-/m1/s1 AQIUGBDBNRZYIA-OAHLLOKOSA-N 50251320 (R)-2-Ethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL465055 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567587 104104494 CHEMBL465055 ZINC40866020 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411693 CCCCOc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C21H25NO3/c1-3-4-9-25-15-10-14-7-8-22(2)17-11-13-5-6-18(23)21(24)20(13)16(12-15)19(14)17/h5-6,10,12,17,23-24H,3-4,7-9,11H2,1-2H3/t17-/m1/s1 BYGOBYFAXDOLTN-QGZVFWFLSA-N 50251327 (R)-2-Butoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL449461 D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567594 104104496 CHEMBL449461 ZINC40835949 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411694 CN1CCc2cc(OCCO)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO4/c1-20-5-4-12-8-13(24-7-6-21)10-14-17(12)15(20)9-11-2-3-16(22)19(23)18(11)14/h2-3,8,10,15,21-23H,4-7,9H2,1H3/t15-/m1/s1 MLSWBRKIYGJEGT-OAHLLOKOSA-N 50251328 CHEMBL457275::[R-(-)-Apomorphine-2-yl]-(2'-hydroxy-ethyl)ether D(2) dopamine receptor Rattus norvegicus 347 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251328&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567595 104104497 CHEMBL457275 ZINC40380136 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411695 CN1CCc2cc(OCCOCCO)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C21H25NO5/c1-22-5-4-14-10-15(27-9-8-26-7-6-23)12-16-19(14)17(22)11-13-2-3-18(24)21(25)20(13)16/h2-3,10,12,17,23-25H,4-9,11H2,1H3/t17-/m1/s1 LUIRUBNQVJTQKP-QGZVFWFLSA-N 50251329 2-{[R-(-)-Apomorphine-2'-oxy]ethoxy}-ethanol::CHEMBL516151 D(2) dopamine receptor Rattus norvegicus 587 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251329&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567596 104104498 CHEMBL516151 ZINC40848455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411696 CSc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C18H19NO2S/c1-19-6-5-11-7-12(22-2)9-13-16(11)14(19)8-10-3-4-15(20)18(21)17(10)13/h3-4,7,9,14,20-21H,5-6,8H2,1-2H3/t14-/m1/s1 OTNVAWFTTKQJMY-CQSZACIVSA-N 50251314 (R)-6-Methyl-2-methylsulfanyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL511711 D(2) dopamine receptor Rattus norvegicus 54.7 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567582 104104491 CHEMBL511711 ZINC40392887 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411697 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 11.1 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411698 CN1CCc2cc(N)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H18N2O2/c1-19-5-4-10-6-11(18)8-12-15(10)13(19)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,20-21H,4-5,7,18H2,1H3/t13-/m1/s1 MJZQRNCUULBFRH-CYBMUJFWSA-N 50016785 (R)-2-Amino-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Amino-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL276042 D(2) dopamine receptor Rattus norvegicus 19.9 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15627829 103928153 CHEMBL276042 ZINC05851200 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411699 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411700 CN1CCc2cc(OCCOCCOc3cc4CCN(C)[C@@H]5Cc6ccc(O)c(O)c6-c(c3)c45)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C38H40N2O7/c1-39-9-7-23-15-25(19-27-33(23)29(39)17-21-3-5-31(41)37(43)35(21)27)46-13-11-45-12-14-47-26-16-24-8-10-40(2)30-18-22-4-6-32(42)38(44)36(22)28(20-26)34(24)30/h3-6,15-16,19-20,29-30,41-44H,7-14,17-18H2,1-2H3/t29-,30-/m1/s1 GJLNFWNMAQBYPC-LOYHVIPDSA-N 50251331 Bis-{[R-(-)-apomorphine-2-oxy]ethyl} ether::CHEMBL444149 D(2) dopamine receptor Rattus norvegicus 17158 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251331&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567598 104104500 CHEMBL444149 ZINC44306425 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411701 CN1CCc2cc(OCCOc3cc4CCN(C)[C@@H]5Cc6ccc(O)c(O)c6-c(c3)c45)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C36H36N2O6/c1-37-9-7-21-13-23(17-25-31(21)27(37)15-19-3-5-29(39)35(41)33(19)25)43-11-12-44-24-14-22-8-10-38(2)28-16-20-4-6-30(40)36(42)34(20)26(18-24)32(22)28/h3-6,13-14,17-18,27-28,39-42H,7-12,15-16H2,1-2H3/t27-,28-/m1/s1 KWKONXOZQQYOJW-VSGBNLITSA-N 50251330 1,2-Bis-[R-(-)-apomorphine-2'-oxy]ethane::CHEMBL442926 D(2) dopamine receptor Rattus norvegicus 345 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567597 104104499 CHEMBL442926 ZINC44280648 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411702 CN1CCc2cc(OCCOc3cc4CCN(C)[C@@H]5Cc6ccc(O)c(O)c6-c(c3)c45)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C36H36N2O6/c1-37-9-7-21-13-23(17-25-31(21)27(37)15-19-3-5-29(39)35(41)33(19)25)43-11-12-44-24-14-22-8-10-38(2)28-16-20-4-6-30(40)36(42)34(20)26(18-24)32(22)28/h3-6,13-14,17-18,27-28,39-42H,7-12,15-16H2,1-2H3/t27-,28-/m1/s1 KWKONXOZQQYOJW-VSGBNLITSA-N 50251330 1,2-Bis-[R-(-)-apomorphine-2'-oxy]ethane::CHEMBL442926 D(2) dopamine receptor Rattus norvegicus 308 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567597 104104499 CHEMBL442926 ZINC44280648 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411703 CN1CCc2cc(OCCOCCOc3cc4CCN(C)[C@@H]5Cc6ccc(O)c(O)c6-c(c3)c45)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C38H40N2O7/c1-39-9-7-23-15-25(19-27-33(23)29(39)17-21-3-5-31(41)37(43)35(21)27)46-13-11-45-12-14-47-26-16-24-8-10-40(2)30-18-22-4-6-32(42)38(44)36(22)28(20-26)34(24)30/h3-6,15-16,19-20,29-30,41-44H,7-14,17-18H2,1-2H3/t29-,30-/m1/s1 GJLNFWNMAQBYPC-LOYHVIPDSA-N 50251331 Bis-{[R-(-)-apomorphine-2-oxy]ethyl} ether::CHEMBL444149 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251331&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567598 104104500 CHEMBL444149 ZINC44306425 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411706 CCOc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C19H21NO3/c1-3-23-13-8-12-6-7-20(2)15-9-11-4-5-16(21)19(22)18(11)14(10-13)17(12)15/h4-5,8,10,15,21-22H,3,6-7,9H2,1-2H3/t15-/m1/s1 AQIUGBDBNRZYIA-OAHLLOKOSA-N 50251320 (R)-2-Ethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL465055 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567587 104104494 CHEMBL465055 ZINC40866020 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411707 CCCOc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C20H23NO3/c1-3-8-24-14-9-13-6-7-21(2)16-10-12-4-5-17(22)20(23)19(12)15(11-14)18(13)16/h4-5,9,11,16,22-23H,3,6-8,10H2,1-2H3/t16-/m1/s1 BCZNYILKVXTJOI-MRXNPFEDSA-N 50251321 (R)-6-Methyl-2-propoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL517491 D(2) dopamine receptor Rattus norvegicus 76 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567588 104104495 CHEMBL517491 ZINC40877998 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411708 CN1CCc2cc(Br)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H16BrNO2/c1-19-5-4-10-6-11(18)8-12-15(10)13(19)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,20-21H,4-5,7H2,1H3/t13-/m1/s1 SETZXJXEHHDPBP-CYBMUJFWSA-N 50010696 (R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL276326 D(2) dopamine receptor Rattus norvegicus 17.7 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010696&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15627832 103923442 CHEMBL276326 ZINC28220764 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411709 COc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C18H19NO3/c1-19-6-5-11-7-12(22-2)9-13-16(11)14(19)8-10-3-4-15(20)18(21)17(10)13/h3-4,7,9,14,20-21H,5-6,8H2,1-2H3/t14-/m1/s1 QGJWYJSOGNAUCY-CQSZACIVSA-N 50010697 (R)-(-)-2-methoxyapomorphine::(R)-2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-methoxyapomorphine::CHEMBL53445 D(2) dopamine receptor Rattus norvegicus 1.12 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010697&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 195499 103923443 CHEMBL53445 ZINC03646006 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411710 CN1CCc2cc(O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO3/c1-18-5-4-10-6-11(19)8-12-15(10)13(18)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,19-21H,4-5,7H2,1H3/t13-/m1/s1 QNBCPLWFVGLFHO-CYBMUJFWSA-N 50010698 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::CHEMBL19130 D(2) dopamine receptor Rattus norvegicus 0.38 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010698&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603797 103923444 CHEMBL19130 ZINC01561184 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412753 COc1ccccc1N1CCN(CCN(CC#C)C2CCc3nc(N)sc3C2)CC1 InChI=1S/C23H31N5OS/c1-3-10-27(18-8-9-19-22(17-18)30-23(24)25-19)14-11-26-12-15-28(16-13-26)20-6-4-5-7-21(20)29-2/h1,4-7,18H,8-17H2,2H3,(H2,24,25) GUCAXHFLECNGRL-UHFFFAOYSA-N 50261302 CHEMBL513352::D-218::N6-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N6-(prop-2-ynyl)-4,5,6,7-tetrahydrobenzo[d]thiaxole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 81.2 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261302&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44577151 104110464 CHEMBL513352 ZINC40893505 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412754 CCCN(CCCCN1CCN(CC1)c1ccccc1)C1CCc2nc(N)sc2C1 InChI=1S/C24H37N5S/c1-2-12-28(21-10-11-22-23(19-21)30-24(25)26-22)14-7-6-13-27-15-17-29(18-16-27)20-8-4-3-5-9-20/h3-5,8-9,21H,2,6-7,10-19H2,1H3,(H2,25,26) AHNMVVBJGPOWFW-UHFFFAOYSA-N 50261280 CHEMBL468022::D-203::N6-(4-(4-Phenylpiperazin-1-yl)butyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiaxole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 769 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866616 104110453 CHEMBL468022 ZINC40880532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412755 CCCN(CCN1CCN(CC1)c1cccc(Cl)c1Cl)C1CCc2nc(N)sc2C1 InChI=1S/C22H31Cl2N5S/c1-2-8-28(16-6-7-18-20(15-16)30-22(25)26-18)12-9-27-10-13-29(14-11-27)19-5-3-4-17(23)21(19)24/h3-5,16H,2,6-15H2,1H3,(H2,25,26) MTSRJJUOIYINNP-UHFFFAOYSA-N 50261279 (+)-N6-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::(-)-N6-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL468017::D-219::N6-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiaxole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 44.2 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866114 104110452 CHEMBL468017 ZINC40879460 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412756 CCCN(CCN1CCN(CC1)c1ccccc1OC)C1CCc2nc(N)sc2C1 InChI=1S/C23H35N5OS/c1-3-10-27(18-8-9-19-22(17-18)30-23(24)25-19)14-11-26-12-15-28(16-13-26)20-6-4-5-7-21(20)29-2/h4-7,18H,3,8-17H2,1-2H3,(H2,24,25) WIZIUHWXARABLD-UHFFFAOYSA-N 50261278 (+)-N6-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::(-)-N6-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL468016::D-210::N6-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiaxole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 243 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866614 104110451 CHEMBL468016 ZINC40879452 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412757 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2nc(N)sc2C1 InChI=1S/C22H33N5S/c1-2-10-26(19-8-9-20-21(17-19)28-22(23)24-20)14-11-25-12-15-27(16-13-25)18-6-4-3-5-7-18/h3-7,19H,2,8-17H2,1H3,(H2,23,24) QXKRKYHYAGPGAN-UHFFFAOYSA-N 50261277 (+)-N6-(2-(4-Phenylpiperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::(-)-N6-(2-(4-Phenylpiperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL468015::N6-(2-(4-Phenylpiperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 1970 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44593628 104110450 CHEMBL468015 ZINC40848964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412758 CCCN(CCN1CCN(CC1)c1ccccc1)C1CCc2ccc(O)cc2C1 InChI=1S/C25H35N3O/c1-2-12-27(24-10-8-21-9-11-25(29)20-22(21)19-24)16-13-26-14-17-28(18-15-26)23-6-4-3-5-7-23/h3-7,9,11,20,24,29H,2,8,10,12-19H2,1H3 POVCSYONXDMZKL-UHFFFAOYSA-N 50109926 7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol::7-{[2-(4-Phenyl-piperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL156639 D(2) dopamine receptor Rattus norvegicus 142 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109926&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10178704 104004815 CHEMBL156639 ZINC22924460 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50412752 Nc1nc2CCC(Cc2s1)N(CCN1CCN(CC1)c1cccc(Cl)c1Cl)CC#C InChI=1S/C22H27Cl2N5S/c1-2-8-28(16-6-7-18-20(15-16)30-22(25)26-18)12-9-27-10-13-29(14-11-27)19-5-3-4-17(23)21(19)24/h1,3-5,16H,6-15H2,(H2,25,26) AWFHSDHVMOYPMI-UHFFFAOYSA-N 50261303 CHEMBL468833::D-220::N6-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)-N6-(prop-2-ynyl)-4,5,6,7-tetrahydrobenzo[d]thiaxole-2,6-diamine D(2) dopamine receptor Rattus norvegicus 34.9 ChEMBL 10.1021/jm701524h 10.7270/Q2BV7GD5 18410082 Biswas, S; Hazeldine, S; Ghosh, B; Parrington, I; Kuzhikandathil, E; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261303&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44577152 104110465 CHEMBL468833 ZINC40893510 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411711 CN1CCc2cc(F)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H16FNO2/c1-19-5-4-10-6-11(18)8-12-15(10)13(19)7-9-2-3-14(20)17(21)16(9)12/h2-3,6,8,13,20-21H,4-5,7H2,1H3/t13-/m1/s1 YBEUIAYJOLGULC-CYBMUJFWSA-N 50016786 (R)-2-Fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL18598 D(2) dopamine receptor Rattus norvegicus 0.43 ChEMBL 10.1016/j.bmc.2008.02.038 10.7270/Q24J0DW0 18313931 Sipos, A; Csutoras, C; Berenyi, S; Uustare, A; Rinken, A University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128965 103928154 CHEMBL18598 ZINC28220760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411163 CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1cccc2c1oc1ccccc21 InChI=1S/C29H23NO3/c1-30-12-11-17-13-18(19-6-4-7-21-20-5-2-3-8-25(20)33-29(19)21)14-22-26(17)23(30)15-16-9-10-24(31)28(32)27(16)22/h2-10,13-14,23,31-32H,11-12,15H2,1H3/t23-/m1/s1 XIJMIVGGWJHATO-HSZRJFAPSA-N 50251034 (R)-(-)-2-(4-dibenzo-furanyl)-apomorphine hydrochloride::CHEMBL465696 D(2) dopamine receptor Rattus norvegicus 1627 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567298 104104365 CHEMBL465696 ZINC40880686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411164 CN(C)c1ccc(cc1)-c1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C25H26N2O2/c1-26(2)19-7-4-15(5-8-19)18-12-17-10-11-27(3)21-14-16-6-9-22(28)25(29)24(16)20(13-18)23(17)21/h4-9,12-13,21,28-29H,10-11,14H2,1-3H3/t21-/m1/s1 BSBMMXOBOAVGQD-OAQYLSRUSA-N 50251029 (R)-(-)-2-(4-N,N-Dimethylaminophenyl)-apomorphine dihydrochloride::CHEMBL458587 D(2) dopamine receptor Rattus norvegicus 484 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251029&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567294 104104363 CHEMBL458587 ZINC40392711 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411176 CN1CCc2cc(C)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C18H19NO2/c1-10-7-12-5-6-19(2)14-9-11-3-4-15(20)18(21)17(11)13(8-10)16(12)14/h3-4,7-8,14,20-21H,5-6,9H2,1-2H3/t14-/m1/s1 QRJZCXSRTBCYIW-CQSZACIVSA-N 50251028 (R)-(-)-2-Methyl-apomorphine hydrochloride::CHEMBL507567::CHEMBL557547 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567292 104104362 CHEMBL557547CHEMBL507567 ZINC40846701 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411179 CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccc(O)cc1 InChI=1S/C23H21NO3/c1-24-9-8-15-10-16(13-2-5-17(25)6-3-13)11-18-21(15)19(24)12-14-4-7-20(26)23(27)22(14)18/h2-7,10-11,19,25-27H,8-9,12H2,1H3/t19-/m1/s1 IEYKUJATGFZIHM-LJQANCHMSA-N 50251027 (R)-(-)-2-(4-Hydroxyphenyl)-apomorphine hydrochloride::CHEMBL458579::CHEMBL517028 D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11639064 104104361 CHEMBL517028CHEMBL458579 ZINC35982742 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411180 CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1 InChI=1S/C23H21NO2/c1-24-10-9-16-11-17(14-5-3-2-4-6-14)12-18-21(16)19(24)13-15-7-8-20(25)23(26)22(15)18/h2-8,11-12,19,25-26H,9-10,13H2,1H3/t19-/m1/s1 NJWHLJABYCIZPL-LJQANCHMSA-N 50251026 (R)-(-)-2-Phenyl-apomorphine hydrochloride::CHEMBL458397::CHEMBL465054 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11515697 104104360 CHEMBL458397CHEMBL465054 ZINC40863607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50411182 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 29644 (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol;hydrate;hydrochloride::APOMORPHINE HYDROCHLORIDE::APOMORPHINE HYDROCHLORIDE HEMIHYDRATE::MLS000069811::SMR000059235::cid_6852399 D(2) dopamine receptor Rattus norvegicus 87 ChEMBL 10.1016/j.bmc.2008.01.057 10.7270/Q2959HB7 18289859 Sipos, A; Kiss, B; Schmidt, E; Greiner, I; Berenyi, S University of Debrecen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 252614856 DB00714 ZINC00446541 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50431829 CCCN(CC[C@H]1CC[C@@H](CC1)NC(=O)\C=C\c1ccccc1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C27H38N4OS/c1-2-17-31(23-13-14-24-25(19-23)33-27(28)30-24)18-16-21-8-11-22(12-9-21)29-26(32)15-10-20-6-4-3-5-7-20/h3-7,10,15,21-23H,2,8-9,11-14,16-19H2,1H3,(H2,28,30)(H,29,32)/b15-10+/t21-,22-,23-/m0/s1 VEYJQJYLFDMMTQ-BUWVWOCESA-N 50253473 CHEMBL492883::N-(4-{2-[((S)-2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-propyl-amino]-ethyl}-cyclohexyl)-3-phenyl-acrylamide D(2) dopamine receptor Rattus norvegicus 330 ChEMBL 10.1021/jm800471h 10.7270/Q2FN161H 18785726 Chen, J; Collins, GT; Zhang, J; Yang, CY; Levant, B; Woods, J; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25099152 104105994 CHEMBL492883 ZINC40955064 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50431830 CCCN(CC[C@H]1CC[C@@H](CC1)NC(=O)c1cc2ccccc2o1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C27H36N4O2S/c1-2-14-31(21-11-12-22-25(17-21)34-27(28)30-22)15-13-18-7-9-20(10-8-18)29-26(32)24-16-19-5-3-4-6-23(19)33-24/h3-6,16,18,20-21H,2,7-15,17H2,1H3,(H2,28,30)(H,29,32)/t18-,20-,21-/m0/s1 WTWMPEGOAVNGOY-JBACZVJFSA-N 50253472 Benzofuran-2-carboxylic acid (4-{2-[((S)-2-amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-propyl-amino]-ethyl}-cyclohexyl)-amide::CHEMBL494511 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1021/jm800471h 10.7270/Q2FN161H 18785726 Chen, J; Collins, GT; Zhang, J; Yang, CY; Levant, B; Woods, J; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25131138 104105993 CHEMBL494511 ZINC40429841 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50431831 Nc1nc2CC[C@@H](Cc2s1)NCC[C@H]1CC[C@@H](CC1)NC(=O)c1ccc2ccccc2c1 InChI=1S/C26H32N4OS/c27-26-30-23-12-11-22(16-24(23)32-26)28-14-13-17-5-9-21(10-6-17)29-25(31)20-8-7-18-3-1-2-4-19(18)15-20/h1-4,7-8,15,17,21-22,28H,5-6,9-14,16H2,(H2,27,30)(H,29,31)/t17-,21-,22-/m0/s1 NAJAFAGBGXSZLZ-HSQYWUDLSA-N 50253471 CHEMBL494510::Naphthalene-2-carboxylic acid {4-[2-((S)-2-amino-4,5,6,7-tetrahydro-benzothiazol-6-ylamino)-ethyl]-cyclohexyl}-amide D(2) dopamine receptor Rattus norvegicus 670 ChEMBL 10.1021/jm800471h 10.7270/Q2FN161H 18785726 Chen, J; Collins, GT; Zhang, J; Yang, CY; Levant, B; Woods, J; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25131135 104105992 CHEMBL494510 ZINC40957028 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50431832 Nc1nc2CC[C@@H](Cc2s1)N(CCC1CCCCC1)CC[C@H]1CC[C@@H](CC1)NC(=O)c1ccc2ccccc2c1 InChI=1S/C34H46N4OS/c35-34-37-31-17-16-30(23-32(31)40-34)38(20-18-24-6-2-1-3-7-24)21-19-25-10-14-29(15-11-25)36-33(39)28-13-12-26-8-4-5-9-27(26)22-28/h4-5,8-9,12-13,22,24-25,29-30H,1-3,6-7,10-11,14-21,23H2,(H2,35,37)(H,36,39)/t25-,29-,30-/m0/s1 QCKRGEPENASGES-ARVREXMNSA-N 50253470 CHEMBL494509::Naphthalene-2-carboxylic acid (4-{2-[((S)-2-amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-(2-cyclohexyl-ethyl)-amino]-ethyl}-cyclohexyl)-amide D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm800471h 10.7270/Q2FN161H 18785726 Chen, J; Collins, GT; Zhang, J; Yang, CY; Levant, B; Woods, J; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25131137 104105991 CHEMBL494509 ZINC49878680 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50431833 CC(C)CCN(CC[C@H]1CC[C@@H](CC1)NC(=O)c1ccc2ccccc2c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C31H42N4OS/c1-21(2)15-17-35(27-13-14-28-29(20-27)37-31(32)34-28)18-16-22-7-11-26(12-8-22)33-30(36)25-10-9-23-5-3-4-6-24(23)19-25/h3-6,9-10,19,21-22,26-27H,7-8,11-18,20H2,1-2H3,(H2,32,34)(H,33,36)/t22-,26-,27-/m0/s1 OLVLMWXYVZNIPP-CAVYSCNFSA-N 50253395 CHEMBL494309::Naphthalene-2-carboxylic acid (4-{2-[((S)-2-amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-(3-methyl-butyl)-amino]-ethyl}-cyclohexyl)-amide D(2) dopamine receptor Rattus norvegicus 345 ChEMBL 10.1021/jm800471h 10.7270/Q2FN161H 18785726 Chen, J; Collins, GT; Zhang, J; Yang, CY; Levant, B; Woods, J; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25130817 104105933 CHEMBL494309 ZINC40972566 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50431834 CCCCN(CC[C@H]1CC[C@@H](CC1)NC(=O)c1ccc2ccccc2c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C30H40N4OS/c1-2-3-17-34(26-14-15-27-28(20-26)36-30(31)33-27)18-16-21-8-12-25(13-9-21)32-29(35)24-11-10-22-6-4-5-7-23(22)19-24/h4-7,10-11,19,21,25-26H,2-3,8-9,12-18,20H2,1H3,(H2,31,33)(H,32,35)/t21-,25-,26-/m0/s1 XLKUVKBPRSKDBI-MZBJOSPHSA-N 50253394 CHEMBL494308::Naphthalene-2-carboxylic acid (4-{2-[((S)-2-amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-butyl-amino]-ethyl}-cyclohexyl)-amide D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm800471h 10.7270/Q2FN161H 18785726 Chen, J; Collins, GT; Zhang, J; Yang, CY; Levant, B; Woods, J; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253394&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25131136 104105932 CHEMBL494308 ZINC40972564 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50431835 CCCN(CC[C@H]1CC[C@@H](CC1)NC(=O)c1ccc2ccccc2c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C29H38N4OS/c1-2-16-33(25-13-14-26-27(19-25)35-29(30)32-26)17-15-20-7-11-24(12-8-20)31-28(34)23-10-9-21-5-3-4-6-22(21)18-23/h3-6,9-10,18,20,24-25H,2,7-8,11-17,19H2,1H3,(H2,30,32)(H,31,34)/t20-,24-,25-/m0/s1 QKVIHOUAEYBMIJ-OPXMRZJTSA-N 50253393 CHEMBL495327::Naphthalene-2-carboxylic acid (4-{2-[((S)-2-amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-propyl-amino]-ethyl}-cyclohexyl)-amide D(2) dopamine receptor Rattus norvegicus 307 ChEMBL 10.1021/jm800471h 10.7270/Q2FN161H 18785726 Chen, J; Collins, GT; Zhang, J; Yang, CY; Levant, B; Woods, J; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25130816 104105931 CHEMBL495327 ZINC40429944 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50431836 CCCN(CCCCNC(=O)c1ccc2ccccc2c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C25H32N4OS/c1-2-14-29(21-11-12-22-23(17-21)31-25(26)28-22)15-6-5-13-27-24(30)20-10-9-18-7-3-4-8-19(18)16-20/h3-4,7-10,16,21H,2,5-6,11-15,17H2,1H3,(H2,26,28)(H,27,30)/t21-/m0/s1 ZIWNVFRTTBQUSJ-NRFANRHFSA-N 50253328 (S)-N-(4-((2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)(propyl)amino)butyl)-2-naphthamide::CHEMBL492664 D(2) dopamine receptor Rattus norvegicus 2.7 ChEMBL 10.1021/jm800471h 10.7270/Q2FN161H 18785726 Chen, J; Collins, GT; Zhang, J; Yang, CY; Levant, B; Woods, J; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253328&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25099153 104105876 CHEMBL492664 ZINC40423298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50431837 COc1ccc2N3CCN(CC[C@H]4CC[C@@H](CC4)NC(=O)c4ccc5ccccc5c4)C[C@H]3CCc2c1 InChI=1S/C32H39N3O2/c1-37-30-14-15-31-26(21-30)10-13-29-22-34(18-19-35(29)31)17-16-23-6-11-28(12-7-23)33-32(36)27-9-8-24-4-2-3-5-25(24)20-27/h2-5,8-9,14-15,20-21,23,28-29H,6-7,10-13,16-19,22H2,1H3,(H,33,36)/t23-,28-,29-/m1/s1 PTRAWPOMIAVCDX-HCLMJZEPSA-N 50253327 CHEMBL524005::Naphthalene-2-carboxylic acid {4-[2-((R)-8-methoxy-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-ethyl]-cyclohexyl}-amide D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm800471h 10.7270/Q2FN161H 18785726 Chen, J; Collins, GT; Zhang, J; Yang, CY; Levant, B; Woods, J; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11386434 104105875 CHEMBL524005 ZINC06745072 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50421583 COc1ccccc1N1CCN(CCCSc2nc3ccccc3s2)CC1 InChI=1S/C21H25N3OS2/c1-25-19-9-4-3-8-18(19)24-14-12-23(13-15-24)11-6-16-26-21-22-17-7-2-5-10-20(17)27-21/h2-5,7-10H,6,11-16H2,1H3 XGBAGSLZEBECDF-UHFFFAOYSA-N 50263290 2-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]thio]benzothiazole::CHEMBL477200 D(2) dopamine receptor Rattus norvegicus 25.8 ChEMBL 10.1021/jm800176x 10.7270/Q2Q81CWG 18598015 Siracusa, MA; Salerno, L; Modica, MN; Pittala, V; Romeo, G; Amato, ME; Nowak, M; Bojarski, AJ; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949690 104111690 CHEMBL477200 ZINC40918920 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50421591 COc1ccccc1N1CCN(CCCCCCSc2nc3ccccc3o2)CC1 InChI=1S/C24H31N3O2S/c1-28-23-13-7-5-11-21(23)27-17-15-26(16-18-27)14-8-2-3-9-19-30-24-25-20-10-4-6-12-22(20)29-24/h4-7,10-13H,2-3,8-9,14-19H2,1H3 UAQAANDOLMXUHK-UHFFFAOYSA-N 50262790 2-[[6-[4-(2-Methoxyphenyl)-1-piperazinyl]hexyl]thio]benzoxazole::CHEMBL476722 D(2) dopamine receptor Rattus norvegicus 46.6 ChEMBL 10.1021/jm800176x 10.7270/Q2Q81CWG 18598015 Siracusa, MA; Salerno, L; Modica, MN; Pittala, V; Romeo, G; Amato, ME; Nowak, M; Bojarski, AJ; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949535 104111355 CHEMBL476722 ZINC40917240 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50421592 COc1ccccc1N1CCN(CCCCSc2nc3ccccc3o2)CC1 InChI=1S/C22H27N3O2S/c1-26-21-11-5-3-9-19(21)25-15-13-24(14-16-25)12-6-7-17-28-22-23-18-8-2-4-10-20(18)27-22/h2-5,8-11H,6-7,12-17H2,1H3 HZFUSQCPFRLRSJ-UHFFFAOYSA-N 50262788 2-[[4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl]thio]benzoxazole::CHEMBL514074 D(2) dopamine receptor Rattus norvegicus 37.3 ChEMBL 10.1021/jm800176x 10.7270/Q2Q81CWG 18598015 Siracusa, MA; Salerno, L; Modica, MN; Pittala, V; Romeo, G; Amato, ME; Nowak, M; Bojarski, AJ; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262788&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949534 104111353 CHEMBL514074 ZINC40915771 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50421593 COc1ccccc1N1CCN(CCCCSc2nc3ccccc3s2)CC1 InChI=1S/C22H27N3OS2/c1-26-20-10-4-3-9-19(20)25-15-13-24(14-16-25)12-6-7-17-27-22-23-18-8-2-5-11-21(18)28-22/h2-5,8-11H,6-7,12-17H2,1H3 ISSGVAQXZMSDSW-UHFFFAOYSA-N 50262787 2-[[4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl]thio]benzothiazole::CHEMBL477765 D(2) dopamine receptor Rattus norvegicus 58.3 ChEMBL 10.1021/jm800176x 10.7270/Q2Q81CWG 18598015 Siracusa, MA; Salerno, L; Modica, MN; Pittala, V; Romeo, G; Amato, ME; Nowak, M; Bojarski, AJ; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262787&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949857 104111352 CHEMBL477765 ZINC40915769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50421594 C(CSc1nc2ccccc2s1)CN1CCN(CC1)c1ncccn1 InChI=1S/C18H21N5S2/c1-2-6-16-15(5-1)21-18(25-16)24-14-4-9-22-10-12-23(13-11-22)17-19-7-3-8-20-17/h1-3,5-8H,4,9-14H2 PEPMTRGKCCXQQJ-UHFFFAOYSA-N 50262742 2-[[3-[4-(Pyrimidin-2-yl)-1-piperazinyl]propyl]thio]benzothiazole::CHEMBL479026 D(2) dopamine receptor Rattus norvegicus 532 ChEMBL 10.1021/jm800176x 10.7270/Q2Q81CWG 18598015 Siracusa, MA; Salerno, L; Modica, MN; Pittala, V; Romeo, G; Amato, ME; Nowak, M; Bojarski, AJ; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262742&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949694 104111317 CHEMBL479026 ZINC40917362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50421595 C(CSc1nc2ccccc2o1)CN1CCN(CC1)c1ccccn1 InChI=1S/C19H22N4OS/c1-2-7-17-16(6-1)21-19(24-17)25-15-5-10-22-11-13-23(14-12-22)18-8-3-4-9-20-18/h1-4,6-9H,5,10-15H2 AHNRDNGNUMIWLX-UHFFFAOYSA-N 50262639 2-[[3-[4-(Pyridin-2-yl)-1-piperazinyl]propyl]thio]benzoxazole::CHEMBL517962 D(2) dopamine receptor Rattus norvegicus 429 ChEMBL 10.1021/jm800176x 10.7270/Q2Q81CWG 18598015 Siracusa, MA; Salerno, L; Modica, MN; Pittala, V; Romeo, G; Amato, ME; Nowak, M; Bojarski, AJ; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262639&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949388 104111267 CHEMBL517962 ZINC40916606 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50421596 C(CSc1nc2ccccc2s1)CN1CCN(CC1)c1ccccn1 InChI=1S/C19H22N4S2/c1-2-7-17-16(6-1)21-19(25-17)24-15-5-10-22-11-13-23(14-12-22)18-8-3-4-9-20-18/h1-4,6-9H,5,10-15H2 WFKQHFRAVGTTCE-UHFFFAOYSA-N 50262582 2-[[3-[4-(Pyridin-2-yl)-1-piperazinyl]propyl]thio]benzothiazole::CHEMBL478413 D(2) dopamine receptor Rattus norvegicus 462 ChEMBL 10.1021/jm800176x 10.7270/Q2Q81CWG 18598015 Siracusa, MA; Salerno, L; Modica, MN; Pittala, V; Romeo, G; Amato, ME; Nowak, M; Bojarski, AJ; Mereghetti, I; Cagnotto, A; Mennini, T Università di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50262582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50262582&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24949693 104111223 CHEMBL478413 ZINC40407775 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50431819 CCCN[C@H]1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1 FASDKYOPVNHBLU-ZETCQYMHSA-N 50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570 D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1021/jm800471h 10.7270/Q2FN161H 18785726 Chen, J; Collins, GT; Zhang, J; Yang, CY; Levant, B; Woods, J; Wang, S University of Michigan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 119570 104010405 8356 CHEMBL301265 DB00413 ZINC03781664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50420909 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m1/s1 WZJSIHGOLMMBAL-MRXNPFEDSA-N 84636 CHEMBL27559::NPA-11-OH-R,(+) D(2) dopamine receptor Rattus norvegicus 28.5 ChEMBL 10.1016/j.bmcl.2008.06.016 10.7270/Q2S46RRC 18585036 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333842 136350736 CHEMBL27559 ZINC05833984 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50420916 CCCN1CCc2cc(OCCO)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C21H25NO3/c1-2-7-22-8-6-15-11-16(25-10-9-23)13-17-20(15)18(22)12-14-4-3-5-19(24)21(14)17/h3-5,11,13,18,23-24H,2,6-10,12H2,1H3/t18-/m1/s1 UAIMCCJYZHBQNQ-GOSISDBHSA-N 50251470 CHEMBL480149::R(-)2-(2-hydroxyethoxy)-11-hydroxy-N-n-propylnoraporphine D(2) dopamine receptor Rattus norvegicus 97 ChEMBL 10.1016/j.bmcl.2008.06.016 10.7270/Q2S46RRC 18585036 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24894057 104104568 CHEMBL480149 ZINC40933700 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50420917 CN1CCc2cc(O)cc-3c2[C@H]1Cc1cccc(OCCO)c-31 InChI=1S/C19H21NO3/c1-20-6-5-13-9-14(22)11-15-18(13)16(20)10-12-3-2-4-17(19(12)15)23-8-7-21/h2-4,9,11,16,21-22H,5-8,10H2,1H3/t16-/m1/s1 FMNUYUVZQXAOTK-MRXNPFEDSA-N 50251445 (R)-11-(2-Hydroxy-ethoxy)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol::CHEMBL480526 D(2) dopamine receptor Rattus norvegicus 3340 ChEMBL 10.1016/j.bmcl.2008.06.016 10.7270/Q2S46RRC 18585036 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567690 104104549 CHEMBL480526 ZINC40410565 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50420918 CCCOc1cccc2C[C@H]3N(C)CCc4cc(O)cc(c34)-c12 InChI=1S/C20H23NO2/c1-3-9-23-18-6-4-5-13-11-17-19-14(7-8-21(17)2)10-15(22)12-16(19)20(13)18/h4-6,10,12,17,22H,3,7-9,11H2,1-2H3/t17-/m1/s1 JQZDCSZYILWJAG-QGZVFWFLSA-N 50251444 (R)-6-Methyl-11-propoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol::CHEMBL480525 D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1016/j.bmcl.2008.06.016 10.7270/Q2S46RRC 18585036 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567689 104104548 CHEMBL480525 ZINC40934132 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50420919 CCOc1cccc2C[C@H]3N(C)CCc4cc(O)cc(c34)-c12 InChI=1S/C19H21NO2/c1-3-22-17-6-4-5-12-10-16-18-13(7-8-20(16)2)9-14(21)11-15(18)19(12)17/h4-6,9,11,16,21H,3,7-8,10H2,1-2H3/t16-/m1/s1 XGQXLURNIMYBEA-MRXNPFEDSA-N 50251443 (R)-11-Ethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol::CHEMBL520573 D(2) dopamine receptor Rattus norvegicus 641 ChEMBL 10.1016/j.bmcl.2008.06.016 10.7270/Q2S46RRC 18585036 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567688 104104547 CHEMBL520573 ZINC40934131 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50420920 CCCN1CCc2cc(OC)cc3-c4ccccc4C[C@@H]1c23 InChI=1S/C20H23NO/c1-3-9-21-10-8-15-11-16(22-2)13-18-17-7-5-4-6-14(17)12-19(21)20(15)18/h4-7,11,13,19H,3,8-10,12H2,1-2H3/t19-/m1/s1 MWRWFSJANWAIKQ-LJQANCHMSA-N 50251442 (R)-2-Methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL480524 D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1016/j.bmcl.2008.06.016 10.7270/Q2S46RRC 18585036 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567687 104104546 CHEMBL480524 ZINC40934130 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50420921 COc1cc2CCN(C)[C@@H]3Cc4ccccc4-c(c1)c23 InChI=1S/C18H19NO/c1-19-8-7-13-9-14(20-2)11-16-15-6-4-3-5-12(15)10-17(19)18(13)16/h3-6,9,11,17H,7-8,10H2,1-2H3/t17-/m1/s1 UVNXQKRQDGRTSE-QGZVFWFLSA-N 50251441 (R)-2-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL520262 D(2) dopamine receptor Rattus norvegicus 731 ChEMBL 10.1016/j.bmcl.2008.06.016 10.7270/Q2S46RRC 18585036 Si, YG; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251441&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567686 104104545 CHEMBL520262 ZINC40935447 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50438281 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50438282 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 155 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50438283 CC(c1nc2ccccc2o1)c1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)cc1 InChI=1S/C30H30FN3O3/c1-20(30-32-26-5-2-3-6-27(26)36-30)21-7-10-24(11-8-21)35-18-4-15-34-16-13-22(14-17-34)29-25-12-9-23(31)19-28(25)37-33-29/h2-3,5-12,19-20,22H,4,13-18H2,1H3 TVMSDNWCQAGRCR-UHFFFAOYSA-N 50133175 CHEMBL3634825 D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133175&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196385 321903531 CHEMBL3634825 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50438284 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(CCc3nc4ccccc4o3)cc2)CC1 InChI=1S/C30H30FN3O3/c31-23-9-12-25-28(20-23)37-33-30(25)22-14-17-34(18-15-22)16-3-19-35-24-10-6-21(7-11-24)8-13-29-32-26-4-1-2-5-27(26)36-29/h1-2,4-7,9-12,20,22H,3,8,13-19H2 JZZWBHDXYLOBGC-UHFFFAOYSA-N 50133174 CHEMBL3634824 D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196384 321903530 CHEMBL3634824 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50438285 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(cc2)-c2nc3ccccc3s2)CC1 InChI=1S/C28H26FN3O2S/c29-21-8-11-23-25(18-21)34-31-27(23)19-12-15-32(16-13-19)14-3-17-33-22-9-6-20(7-10-22)28-30-24-4-1-2-5-26(24)35-28/h1-2,4-11,18-19H,3,12-17H2 PVHCQGPPCAOZER-UHFFFAOYSA-N 50133173 CHEMBL3634823 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196383 321903529 CHEMBL3634823 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50438286 Fc1ccc2c(noc2c1)C1CCN(CCCCOc2ccc(cc2)-c2nc3ccccc3o2)CC1 InChI=1S/C29H28FN3O3/c30-22-9-12-24-27(19-22)36-32-28(24)20-13-16-33(17-14-20)15-3-4-18-34-23-10-7-21(8-11-23)29-31-25-5-1-2-6-26(25)35-29/h1-2,5-12,19-20H,3-4,13-18H2 LRQCCVWNHKQSPO-UHFFFAOYSA-N 50133172 CHEMBL3634822 D(2) dopamine receptor Rattus norvegicus 2198 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196382 321903528 CHEMBL3634822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50438287 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(Cc3nc4ccccc4o3)cc2)CC1 InChI=1S/C29H28FN3O3/c30-22-8-11-24-27(19-22)36-32-29(24)21-12-15-33(16-13-21)14-3-17-34-23-9-6-20(7-10-23)18-28-31-25-4-1-2-5-26(25)35-28/h1-2,4-11,19,21H,3,12-18H2 DRXDGURYDDKZLG-UHFFFAOYSA-N 50133171 CHEMBL3634821 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196381 321903527 CHEMBL3634821 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50438288 Fc1ccc2c(noc2c1)C1CCN(CCCOc2cccc(c2)-c2nc3ccccc3o2)CC1 InChI=1S/C28H26FN3O3/c29-21-9-10-23-26(18-21)35-31-27(23)19-11-14-32(15-12-19)13-4-16-33-22-6-3-5-20(17-22)28-30-24-7-1-2-8-25(24)34-28/h1-3,5-10,17-19H,4,11-16H2 NBVRWKVJYNXODW-UHFFFAOYSA-N 50133170 CHEMBL3634820 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196380 321903526 CHEMBL3634820 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50438289 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(-c3nc4ccccc4o3)c(F)c2)CC1 InChI=1S/C28H25F2N3O3/c29-19-6-8-22-26(16-19)36-32-27(22)18-10-13-33(14-11-18)12-3-15-34-20-7-9-21(23(30)17-20)28-31-24-4-1-2-5-25(24)35-28/h1-2,4-9,16-18H,3,10-15H2 SZAARPVLKHDSNR-UHFFFAOYSA-N 50133169 CHEMBL3634819 D(2) dopamine receptor Rattus norvegicus 143 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196379 321903525 CHEMBL3634819 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442558 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 311 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442560 Oc1cccc2C[C@H]3[C@@H](CCCN3CCN3CCN(CC3)c3cccc(Cl)c3Cl)Cc12 InChI=1S/C25H31Cl2N3O/c26-21-6-2-7-22(25(21)27)30-14-11-28(12-15-30)10-13-29-9-3-5-19-16-20-18(17-23(19)29)4-1-8-24(20)31/h1-2,4,6-8,19,23,31H,3,5,9-17H2/t19-,23-/m0/s1 FGHCYRVZNIWGCZ-CVDCTZTESA-N 50273468 (+/-)-trans-1-{2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl}-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-ol::CHEMBL456979 D(2) dopamine receptor Rattus norvegicus 136 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25179489 104117589 CHEMBL456979 ZINC40847887 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442561 Oc1cccc2C[C@H]3[C@@H](CCCN3CCN3CCN(CC3)c3ccccc3)Cc12 InChI=1S/C25H33N3O/c29-25-10-4-6-20-19-24-21(18-23(20)25)7-5-11-28(24)17-14-26-12-15-27(16-13-26)22-8-2-1-3-9-22/h1-4,6,8-10,21,24,29H,5,7,11-19H2/t21-,24-/m0/s1 BDSPUJFGSUKYBJ-URXFXBBRSA-N 50273467 (+/-)-trans-1-[2-(4-Phenylpiperazin-1-yl)ethyl]-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-ol::CHEMBL514411 D(2) dopamine receptor Rattus norvegicus 1712 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25179487 104117588 CHEMBL514411 ZINC40847620 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442562 Oc1cccc2[C@@H]3CCCN(CCN4CCN(CC4)c4ccccc4)[C@H]3CCc12 InChI=1S/C25H33N3O/c29-25-10-4-8-21-22-9-5-13-28(24(22)12-11-23(21)25)19-16-26-14-17-27(18-15-26)20-6-2-1-3-7-20/h1-4,6-8,10,22,24,29H,5,9,11-19H2/t22-,24-/m0/s1 QQRPTUXXSDJYLW-UPVQGACJSA-N 50273418 (+/-)-trans-4-(2-(4-Phenylpiperazin-1-yl)ethyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-7-ol::(-)-(4aS,10bS)-trans-4-(2-(4-Phenylpiperazin-1-yl)ethyl)-1,2,3,4,4a,5,6,10b-octa-hydrobenzo[f]quinolin-7-ol::CHEMBL516296 D(2) dopamine receptor Rattus norvegicus 23.6 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25147748 104117548 CHEMBL516296 ZINC40847071 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442563 Oc1cccc2[C@H]3CCCN(CCN4CCN(CC4)c4ccccc4)[C@@H]3CCc12 InChI=1S/C25H33N3O/c29-25-10-4-8-21-22-9-5-13-28(24(22)12-11-23(21)25)19-16-26-14-17-27(18-15-26)20-6-2-1-3-7-20/h1-4,6-8,10,22,24,29H,5,9,11-19H2/t22-,24-/m1/s1 QQRPTUXXSDJYLW-ISKFKSNPSA-N 50273419 (+)-(4aR,10aR)-trans-4-(2-(4-Phenylpiperazin-1-yl)ethyl)-1,2,3,4,4a,5,6,10b-octa-hydrobenzo[f]quinolin-7-ol::CHEMBL513931 D(2) dopamine receptor Rattus norvegicus 835 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273419&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24767804 104117549 CHEMBL513931 ZINC40847308 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442564 Oc1cccc2[C@@H]3CCCN(CCN4CCN(CC4)c4ccccc4)[C@H]3CCc12 InChI=1S/C25H33N3O/c29-25-10-4-8-21-22-9-5-13-28(24(22)12-11-23(21)25)19-16-26-14-17-27(18-15-26)20-6-2-1-3-7-20/h1-4,6-8,10,22,24,29H,5,9,11-19H2/t22-,24-/m0/s1 QQRPTUXXSDJYLW-UPVQGACJSA-N 50273418 (+/-)-trans-4-(2-(4-Phenylpiperazin-1-yl)ethyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-7-ol::(-)-(4aS,10bS)-trans-4-(2-(4-Phenylpiperazin-1-yl)ethyl)-1,2,3,4,4a,5,6,10b-octa-hydrobenzo[f]quinolin-7-ol::CHEMBL516296 D(2) dopamine receptor Rattus norvegicus 23.6 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25147748 104117548 CHEMBL516296 ZINC40847071 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442565 Oc1ccc2C[C@@H]3CCCN(CCCCN4CCN(CC4)c4ccccc4)[C@H]3Cc2c1 InChI=1S/C27H37N3O/c31-26-11-10-22-19-23-7-6-14-30(27(23)21-24(22)20-26)13-5-4-12-28-15-17-29(18-16-28)25-8-2-1-3-9-25/h1-3,8-11,20,23,27,31H,4-7,12-19,21H2/t23-,27-/m0/s1 KKEATGXCXUWNJJ-HOFKKMOUSA-N 50273417 (+/-)-trans-1-[4-(4-Phenylpiperazin-1-yl)butyl]-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-8-ol::CHEMBL456336 D(2) dopamine receptor Rattus norvegicus 289 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273417&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25178929 104117547 CHEMBL456336 ZINC40847069 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442566 Oc1ccc2C[C@@H]3CCCN(CCN4CCN(CC4)c4cccc(Cl)c4Cl)[C@H]3Cc2c1 InChI=1S/C25H31Cl2N3O/c26-22-4-1-5-23(25(22)27)30-13-10-28(11-14-30)9-12-29-8-2-3-19-15-18-6-7-21(31)16-20(18)17-24(19)29/h1,4-7,16,19,24,31H,2-3,8-15,17H2/t19-,24-/m0/s1 WHAZETDLHOXKNK-CYFREDJKSA-N 50273343 (+/-)-trans-1-{2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl}-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-8-ol::CHEMBL464183 D(2) dopamine receptor Rattus norvegicus 338 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25178749 104117492 CHEMBL464183 ZINC40873789 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442567 Oc1ccc2C[C@@H]3CCCN(CCN4CCN(CC4)c4cccc(Cl)c4Cl)[C@@H]3Cc2c1 InChI=1S/C25H31Cl2N3O/c26-22-4-1-5-23(25(22)27)30-13-10-28(11-14-30)9-12-29-8-2-3-19-15-18-6-7-21(31)16-20(18)17-24(19)29/h1,4-7,16,19,24,31H,2-3,8-15,17H2/t19-,24+/m0/s1 WHAZETDLHOXKNK-YADARESESA-N 50273341 (+/-)-cis-1-{2-[4-(2,3-Dichlorophenyl)piperazin-1-yl]ethyl}-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-8-ol::CHEMBL517014 D(2) dopamine receptor Rattus norvegicus 148 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25178546 104117490 CHEMBL517014 ZINC40873576 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442568 Oc1ccc2C[C@@H]3CCCN(CCN4CCN(CC4)c4ccccc4)[C@@H]3Cc2c1 InChI=1S/C25H33N3O/c29-24-9-8-20-17-21-5-4-10-28(25(21)19-22(20)18-24)16-13-26-11-14-27(15-12-26)23-6-2-1-3-7-23/h1-3,6-9,18,21,25,29H,4-5,10-17,19H2/t21-,25+/m0/s1 NAPNWCZWDZJHJF-SQJMNOBHSA-N 50273340 (+/-)-cis-1-[2-(4-Phenylpiperazin-1-yl)ethyl]-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-8-ol::CHEMBL463576 D(2) dopamine receptor Rattus norvegicus 3326 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25178543 104117489 CHEMBL463576 ZINC40873767 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442569 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccccc1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C28H37N5S/c1-2-14-32(25-12-13-26-27(21-25)34-28(29)30-26)18-15-31-16-19-33(20-17-31)24-10-8-23(9-11-24)22-6-4-3-5-7-22/h3-11,25H,2,12-21H2,1H3,(H2,29,30)/t25-/m0/s1 YDLWLYDTYNHXBM-VWLOTQADSA-N 50273996 (S)-N*6*-[2-(4-Biphenyl-4-yl-piperazin-1-yl)-ethyl]-N*6*-propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine::(S)-N6-(2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL514885::D-264 D(2) dopamine receptor Rattus norvegicus 234 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866612 104117939 CHEMBL514885 ZINC40379927 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442570 CCCN(CCN1CCN(CC1)c1ccccc1)[C@@H]1CCc2nc(N)sc2C1 InChI=1S/C22H33N5S/c1-2-10-26(19-8-9-20-21(17-19)28-22(23)24-20)14-11-25-12-15-27(16-13-25)18-6-4-3-5-7-18/h3-7,19H,2,8-17H2,1H3,(H2,23,24)/t19-/m1/s1 QXKRKYHYAGPGAN-LJQANCHMSA-N 50273995 (R)-N6-(2-(4-phenylpiperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL456811 D(2) dopamine receptor Rattus norvegicus 1979 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866446 104117938 CHEMBL456811 ZINC40380115 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442571 CCCN(CCN1CCN(CC1)c1ccccc1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C22H33N5S/c1-2-10-26(19-8-9-20-21(17-19)28-22(23)24-20)14-11-25-12-15-27(16-13-25)18-6-4-3-5-7-18/h3-7,19H,2,8-17H2,1H3,(H2,23,24)/t19-/m0/s1 QXKRKYHYAGPGAN-IBGZPJMESA-N 50273994 (S)-N6-(2-(4-phenylpiperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL456597 D(2) dopamine receptor Rattus norvegicus 243 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866112 104117937 CHEMBL456597 ZINC40848964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442572 Oc1ccc2CC[C@H]3[C@@H](CCCN3CCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C25H33N3O/c29-22-10-8-20-9-11-25-23(24(20)19-22)7-4-12-28(25)18-15-26-13-16-27(17-14-26)21-5-2-1-3-6-21/h1-3,5-6,8,10,19,23,25,29H,4,7,9,11-18H2/t23-,25-/m0/s1 KNPPDPMAXUBRQJ-ZCYQVOJMSA-N 50273993 (4aS,10bS)-4-(2-(4-phenylpiperazin-1-yl)ethyl)-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-9-ol::CHEMBL456596 D(2) dopamine receptor Rattus norvegicus 219 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25179491 104117936 CHEMBL456596 ZINC40848962 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442573 CCCN(CCN1CCN(CC1)c1ccccc1)[C@@H]1CCc2c(O)cccc2C1 InChI=1S/C25H35N3O/c1-2-13-27(23-11-12-24-21(20-23)7-6-10-25(24)29)17-14-26-15-18-28(19-16-26)22-8-4-3-5-9-22/h3-10,23,29H,2,11-20H2,1H3/t23-/m1/s1 ACDYFMOSSUKHJD-HSZRJFAPSA-N 50273939 (R)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::CHEMBL457025::D-237 D(2) dopamine receptor Rattus norvegicus 238 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24754478 104117902 CHEMBL457025 ZINC28964117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442574 CCCN(CCN1CCN(CC1)c1ccccc1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C25H35N3O/c1-2-13-27(23-11-12-24-21(20-23)7-6-10-25(24)29)17-14-26-15-18-28(19-16-26)22-8-4-3-5-9-22/h3-10,23,29H,2,11-20H2,1H3/t23-/m0/s1 ACDYFMOSSUKHJD-QHCPKHFHSA-N 50273938 (-)-(S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::(S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::CHEMBL457024::D-237 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273938&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24754542 104117901 CHEMBL457024 ZINC28964118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442575 CCCN(CCN1CCN(CC1)c1ccccc1)[C@@H]1CCc2ccc(O)cc2C1 InChI=1S/C25H35N3O/c1-2-12-27(24-10-8-21-9-11-25(29)20-22(21)19-24)16-13-26-14-17-28(18-15-26)23-6-4-3-5-7-23/h3-7,9,11,20,24,29H,2,8,10,12-19H2,1H3/t24-/m1/s1 POVCSYONXDMZKL-XMMPIXPASA-N 50273937 (+)-(R)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::(R)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL456825::D-315 D(2) dopamine receptor Rattus norvegicus 40.6 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273937&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44588498 104117900 CHEMBL456825 ZINC22924455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442576 CCCN(CCN1CCN(CC1)c1ccccc1)[C@H]1CCc2ccc(O)cc2C1 InChI=1S/C25H35N3O/c1-2-12-27(24-10-8-21-9-11-25(29)20-22(21)19-24)16-13-26-14-17-28(18-15-26)23-6-4-3-5-7-23/h3-7,9,11,20,24,29H,2,8,10,12-19H2,1H3/t24-/m0/s1 POVCSYONXDMZKL-DEOSSOPVSA-N 50273936 (S)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL458088 D(2) dopamine receptor Rattus norvegicus 809 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273936&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44588497 104117899 CHEMBL458088 ZINC22924460 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442577 CCCN1CCC[C@@H]2[C@@H]1CCc1c(O)cccc21 InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15-/m0/s1 ANYSYRVXKLTFPB-ZFWWWQNUSA-N 50273466 (+/-)-trans-4-propyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolin-7-ol::4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol::CHEMBL450863 D(2) dopamine receptor Rattus norvegicus 347 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039958 104117587 CHEMBL450863 ZINC05833784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442578 CCCN1CCC[C@@H]2Cc3c(O)cccc3C[C@@H]12 InChI=1S/C16H23NO/c1-2-8-17-9-4-6-13-10-14-12(11-15(13)17)5-3-7-16(14)18/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15-/m1/s1 GNIVTAIHBFVOJN-UKRRQHHQSA-N 50273465 (+/-)-trans-1-Propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-6-ol::CHEMBL3098131::CHEMBL455497 D(2) dopamine receptor Rattus norvegicus 2780 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13851595 104117586 CHEMBL3098131CHEMBL455497 ZINC13826411 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50442601 Oc1ccc2C[C@@H]3CCCN(CCN4CCN(CC4)c4ccccc4)[C@H]3Cc2c1 InChI=1S/C25H33N3O/c29-24-9-8-20-17-21-5-4-10-28(25(21)19-22(20)18-24)16-13-26-11-14-27(15-12-26)23-6-2-1-3-7-23/h1-3,6-9,18,21,25,29H,4-5,10-17,19H2/t21-,25-/m0/s1 NAPNWCZWDZJHJF-OFVILXPXSA-N 50273342 (+/-)-trans-1-[2-(4-Phenylpiperazin-1-yl)ethyl]-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-8-ol::CHEMBL464182 D(2) dopamine receptor Rattus norvegicus 2522 ChEMBL 10.1021/jm8008629 10.7270/Q22B8XWJ 19053758 Brown, DA; Kharkar, PS; Parrington, I; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25179885 104117491 CHEMBL464182 ZINC40873578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437853 C(COc1ccc(cc1)-c1nc2ccccc2o1)CN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C27H26N4O2S/c1-4-9-25-22(6-1)26(29-34-25)31-17-15-30(16-18-31)14-5-19-32-21-12-10-20(11-13-21)27-28-23-7-2-3-8-24(23)33-27/h1-4,6-13H,5,14-19H2 OTHIKKZLZJYTPI-UHFFFAOYSA-N 50133179 CHEMBL3634814 D(2) dopamine receptor Rattus norvegicus 879 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133179&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196374 321903535 CHEMBL3634814 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437854 Cc1ccc2oc(nc2c1)-c1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)cc1 InChI=1S/C29H28FN3O3/c1-19-3-10-26-25(17-19)31-29(35-26)21-4-7-23(8-5-21)34-16-2-13-33-14-11-20(12-15-33)28-24-9-6-22(30)18-27(24)36-32-28/h3-10,17-18,20H,2,11-16H2,1H3 GGBAWSCTEFODHQ-UHFFFAOYSA-N 50133180 CHEMBL3634815 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133180&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196375 321903536 CHEMBL3634815 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437855 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(cc2)-c2nc3cc(Cl)ccc3o2)CC1 InChI=1S/C28H25ClFN3O3/c29-20-4-9-25-24(16-20)31-28(35-25)19-2-6-22(7-3-19)34-15-1-12-33-13-10-18(11-14-33)27-23-8-5-21(30)17-26(23)36-32-27/h2-9,16-18H,1,10-15H2 SDPWBLYTEKGWLP-UHFFFAOYSA-N 50133178 CHEMBL3634816 D(2) dopamine receptor Rattus norvegicus 660 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133178&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196376 321903534 CHEMBL3634816 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437856 Cc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)-c1nc2ccccc2o1 InChI=1S/C29H28FN3O3/c1-19-17-21(29-31-24-5-2-3-6-26(24)35-29)7-10-25(19)34-16-4-13-33-14-11-20(12-15-33)28-23-9-8-22(30)18-27(23)36-32-28/h2-3,5-10,17-18,20H,4,11-16H2,1H3 MCWAVMLFDUJCCA-UHFFFAOYSA-N 50133177 CHEMBL3634817 D(2) dopamine receptor Rattus norvegicus 1589 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196377 321903533 CHEMBL3634817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437857 COc1cc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)ccc1-c1nc2ccccc2o1 InChI=1S/C29H28FN3O4/c1-34-26-18-21(8-10-23(26)29-31-24-5-2-3-6-25(24)36-29)35-16-4-13-33-14-11-19(12-15-33)28-22-9-7-20(30)17-27(22)37-32-28/h2-3,5-10,17-19H,4,11-16H2,1H3 QLUKUUCJXHPADS-UHFFFAOYSA-N 50133176 CHEMBL3634818 D(2) dopamine receptor Rattus norvegicus 1192 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133176&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196378 321903532 CHEMBL3634818 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444210 Clc1ccc(N2CCN(CCCCNC(=O)c3cc4cc(Cl)ccc4[nH]3)CC2)c(Cl)c1 InChI=1S/C23H25Cl3N4O/c24-17-3-5-20-16(13-17)14-21(28-20)23(31)27-7-1-2-8-29-9-11-30(12-10-29)22-6-4-18(25)15-19(22)26/h3-6,13-15,28H,1-2,7-12H2,(H,27,31) VGPQHQDBSBJSAG-UHFFFAOYSA-N 50131930 5-Chloro-1H-indole-2-carboxylic acid {4-[4-(2,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::5-chloro-N-(4-(4-(2,4-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide::CHEMBL126889 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10367857 104022955 CHEMBL126889 ZINC13525845 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444211 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444212 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Rattus norvegicus 0.8 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444214 Clc1ccc(N2CCN(CCCCNC(=O)c3cc4ccccc4[nH]3)CC2)c(Cl)c1 InChI=1S/C23H26Cl2N4O/c24-18-7-8-22(19(25)16-18)29-13-11-28(12-14-29)10-4-3-9-26-23(30)21-15-17-5-1-2-6-20(17)27-21/h1-2,5-8,15-16,27H,3-4,9-14H2,(H,26,30) CYNHGJORJGHXEX-UHFFFAOYSA-N 50131925 1H-Indole-2-carboxylic acid {4-[4-(2,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL339960::N-(4-(4-(2,4-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131925&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10411237 104022950 CHEMBL339960 ZINC03817191 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444215 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444216 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444217 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444218 COc1cccc2cc3CN(CCCCN4CCn5c(cc6ccccc56)C4=O)CCn3c12 InChI=1S/C27H30N4O2/c1-33-25-10-6-8-21-17-22-19-28(13-15-30(22)26(21)25)11-4-5-12-29-14-16-31-23-9-3-2-7-20(23)18-24(31)27(29)32/h2-3,6-10,17-18H,4-5,11-16,19H2,1H3 GPANICKLGIVBML-UHFFFAOYSA-N 50265446 3,4-Dihydro-2-[4-(3,4-dihydro-6-methoxypyrazino[1,2-a]indol-2(1H)-yl)butyl]pyrazino[1,2-a]indol-1(2H)-one::CHEMBL495573 D(2) dopamine receptor Rattus norvegicus 3530 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11676600 104113214 CHEMBL495573 ZINC38226296 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444219 Clc1cccc(N2CCN(CCCCCOc3cc4ccccc4cn3)CC2)c1Cl InChI=1S/C24H27Cl2N3O/c25-21-9-6-10-22(24(21)26)29-14-12-28(13-15-29)11-4-1-5-16-30-23-17-19-7-2-3-8-20(19)18-27-23/h2-3,6-10,17-18H,1,4-5,11-16H2 KPLQQMQZQUMPCN-UHFFFAOYSA-N 50265445 3-[5-[4-(2,3-Dichlorophenyl)piperazin-1-yl]pentyloxy]isoquinoline::CHEMBL495572 D(2) dopamine receptor Rattus norvegicus 75 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25186023 104113213 CHEMBL495572 ZINC40955299 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444220 Clc1cccc(N2CCN(CCCCOc3cc4ccccc4cn3)CC2)c1Cl InChI=1S/C23H25Cl2N3O/c24-20-8-5-9-21(23(20)25)28-13-11-27(12-14-28)10-3-4-15-29-22-16-18-6-1-2-7-19(18)17-26-22/h1-2,5-9,16-17H,3-4,10-15H2 MHFKMHGOYNDZEI-UHFFFAOYSA-N 50265444 3-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy]isoquinoline::CHEMBL522044 D(2) dopamine receptor Rattus norvegicus 215 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25186839 104113212 CHEMBL522044 ZINC40955759 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444221 Clc1cccc(N2CCN(CCCCOc3ccc4cccnc4c3)CC2)c1Cl InChI=1S/C23H25Cl2N3O/c24-20-6-3-7-22(23(20)25)28-14-12-27(13-15-28)11-1-2-16-29-19-9-8-18-5-4-10-26-21(18)17-19/h3-10,17H,1-2,11-16H2 FUOMYSOASQSWCG-UHFFFAOYSA-N 50265390 7-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyloxy]quinoline::CHEMBL497988 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265390&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25186022 104113159 CHEMBL497988 ZINC40973903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444222 Cc1cccc(c1)N1CCN(CCCCNC(=O)c2cc3ccccc3o2)CC1 InChI=1S/C24H29N3O2/c1-19-7-6-9-21(17-19)27-15-13-26(14-16-27)12-5-4-11-25-24(28)23-18-20-8-2-3-10-22(20)29-23/h2-3,6-10,17-18H,4-5,11-16H2,1H3,(H,25,28) DIJKUIXRAWOVGJ-UHFFFAOYSA-N 50265376 CHEMBL496739::N-(4-(4-(m-Tolyl)piperazin-1-yl)butyl)benzo[b]furan-2-carboxamide::N-(4-(4-m-tolylpiperazin-1-yl)butyl)benzofuran-2-carboxamide D(2) dopamine receptor Rattus norvegicus 263 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265376&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11696813 104113153 CHEMBL496739 ZINC26954229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444223 Clc1cccc(N2CCN(CCCCN3CCn4c(cc5ccccc45)C3=O)CC2)c1Cl InChI=1S/C25H28Cl2N4O/c26-20-7-5-9-22(24(20)27)29-14-12-28(13-15-29)10-3-4-11-30-16-17-31-21-8-2-1-6-19(21)18-23(31)25(30)32/h1-2,5-9,18H,3-4,10-17H2 DGKURWUVIVQHCD-UHFFFAOYSA-N 50265375 CHEMBL496531::N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]3,4-dihydropyrazino[1,2-a]indol-1(2H)-one D(2) dopamine receptor Rattus norvegicus 122 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265375&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11712530 104113152 CHEMBL496531 ZINC34637497 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444224 Clc1ccc(N2CCN(CCCCN3CCn4c(cc5ccccc45)C3=O)CC2)c(Cl)c1 InChI=1S/C25H28Cl2N4O/c26-20-7-8-23(21(27)18-20)29-13-11-28(12-14-29)9-3-4-10-30-15-16-31-22-6-2-1-5-19(22)17-24(31)25(30)32/h1-2,5-8,17-18H,3-4,9-16H2 XLZXIDKEIKKBGP-UHFFFAOYSA-N 50265374 CHEMBL497574::N-[4-[4-(2,4-Dichlorophenyl)piperazin-1-yl]butyl]3,4-dihydropyrazino[1,2-a]indol-1(2H)-one D(2) dopamine receptor Rattus norvegicus 229 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25186021 104113151 CHEMBL497574 ZINC40975182 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444225 O=C1N(CCCCN2CCN(CC2)c2cccc(c2)C#N)CCn2c1cc1ccccc21 InChI=1S/C26H29N5O/c27-20-21-6-5-8-23(18-21)29-14-12-28(13-15-29)10-3-4-11-30-16-17-31-24-9-2-1-7-22(24)19-25(31)26(30)32/h1-2,5-9,18-19H,3-4,10-17H2 MHGRSFGKSQVLIY-UHFFFAOYSA-N 50265373 CHEMBL497573::N-[4-[4-(3-Cyanophenyl)piperazin-1-yl]butyl]3,4-dihydropyrazino[1,2-a]indol-1(2H)-one D(2) dopamine receptor Rattus norvegicus 339 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265373&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11704609 104113150 CHEMBL497573 ZINC40975180 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444226 O=C(NCCCCN1CCN(CC1)c1cccc(c1)C#N)c1cc2ccccc2o1 InChI=1S/C24H26N4O2/c25-18-19-6-5-8-21(16-19)28-14-12-27(13-15-28)11-4-3-10-26-24(29)23-17-20-7-1-2-9-22(20)30-23/h1-2,5-9,16-17H,3-4,10-15H2,(H,26,29) AFUIBDRITZEBAF-UHFFFAOYSA-N 50265759 CHEMBL497604::N-[4-[4-(3-Cyanophenyl)piperazin-1-yl]butyl]benzo[b]furan-2-carboxamide D(2) dopamine receptor Rattus norvegicus 859 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265759&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11596521 104113413 CHEMBL497604 ZINC35901290 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444227 Clc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4cn3)CC2)c1Cl InChI=1S/C24H26Cl2N4O/c25-20-8-5-9-22(23(20)26)30-14-12-29(13-15-30)11-4-3-10-27-24(31)21-16-18-6-1-2-7-19(18)17-28-21/h1-2,5-9,16-17H,3-4,10-15H2,(H,27,31) JMYVVZJJTRVCDC-UHFFFAOYSA-N 50265775 CHEMBL462508::N-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]isoquinoline-3-carboxamide D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25186569 104113428 CHEMBL462508 ZINC40867283 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444228 Clc1cccc(c1)N1CCN(CCCCNC(=O)c2cc3ccccc3cn2)CC1 InChI=1S/C24H27ClN4O/c25-21-8-5-9-22(17-21)29-14-12-28(13-15-29)11-4-3-10-26-24(30)23-16-19-6-1-2-7-20(19)18-27-23/h1-2,5-9,16-18H,3-4,10-15H2,(H,26,30) UPKZNVQHJZHSGN-UHFFFAOYSA-N 50265776 CHEMBL461236::N-[4-[4-(3-Chlorophenyl)piperazin-1-yl]butyl]isoquinoline-3-carboxamide D(2) dopamine receptor Rattus norvegicus 1039 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265776&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11654739 104113429 CHEMBL461236 ZINC40393501 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444229 COc1cccc2cc3CN(CCCCNC(=O)C4=NCc5ccccc5C4)CCn3c12 InChI=1S/C26H30N4O2/c1-32-24-10-6-9-20-15-22-18-29(13-14-30(22)25(20)24)12-5-4-11-27-26(31)23-16-19-7-2-3-8-21(19)17-28-23/h2-3,6-10,15H,4-5,11-14,16-18H2,1H3,(H,27,31) XLDORXGCMVUJKE-UHFFFAOYSA-N 50265777 CHEMBL461023::N-[4-(3,4-Dihydro-6-methoxypyrazino[1,2-a]1ndol-2(1H)-yl)-butyl]isoquinoline-3-carboxamide D(2) dopamine receptor Rattus norvegicus 1012 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91935077 104113430 CHEMBL461023 ZINC49844843 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50444230 COc1cccc2[nH]c3CN(CCCCNC(=O)C4=NCc5ccccc5C4)CCc3c12 InChI=1S/C26H30N4O2/c1-32-24-10-6-9-21-25(24)20-11-14-30(17-23(20)29-21)13-5-4-12-27-26(31)22-15-18-7-2-3-8-19(18)16-28-22/h2-3,6-10,29H,4-5,11-17H2,1H3,(H,27,31) BURMBJGIJZXZNP-UHFFFAOYSA-N 50265778 CHEMBL517730::N-[4-(1,2,3,4-Tetrahydro-5-methoxy--carbolin-2-yl)butyl]isoquinoline-3-carboxamide D(2) dopamine receptor Rattus norvegicus 6475 ChEMBL 10.1021/jm800689g 10.7270/Q2J67GSD 19072656 Butini, S; Gemma, S; Campiani, G; Franceschini, S; Trotta, F; Borriello, M; Ceres, N; Ros, S; Coccone, SS; Bernetti, M; De Angelis, M; Brindisi, M; Nacci, V; Fiorini, I; Novellino, E; Cagnotto, A; Mennini, T; Sandager-Nielsen, K; Andreasen, JT; Scheel-Kruger, J; Mikkelsen, JD; Fattorusso, C University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91935078 104113431 CHEMBL517730 ZINC49573642 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437864 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(cc2)-c2nc3ccccc3o2)CC1 InChI=1S/C28H26FN3O3/c29-21-8-11-23-26(18-21)35-31-27(23)19-12-15-32(16-13-19)14-3-17-33-22-9-6-20(7-10-22)28-30-24-4-1-2-5-25(24)34-28/h1-2,4-11,18-19H,3,12-17H2 LKVJROOIPKZVDQ-UHFFFAOYSA-N 50133181 CHEMBL3634813 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196373 321903537 CHEMBL3634813 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437865 Fc1ccc(C(=O)C2CCN(CCCOc3ccc(cc3)-c3nc4ccccc4o3)CC2)c(F)c1 InChI=1S/C28H26F2N2O3/c29-21-8-11-23(24(30)18-21)27(33)19-12-15-32(16-13-19)14-3-17-34-22-9-6-20(7-10-22)28-31-25-4-1-2-5-26(25)35-28/h1-2,4-11,18-19H,3,12-17H2 KMSFTQMRXXGIJL-UHFFFAOYSA-N 50133182 CHEMBL3634812 D(2) dopamine receptor Rattus norvegicus 408 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196372 321903538 CHEMBL3634812 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437866 C(COc1ccc(cc1)-c1nc2ccccc2o1)CN1CCN(CC1)c1ncccn1 InChI=1S/C24H25N5O2/c1-2-6-22-21(5-1)27-23(31-22)19-7-9-20(10-8-19)30-18-4-13-28-14-16-29(17-15-28)24-25-11-3-12-26-24/h1-3,5-12H,4,13-18H2 MOJQSPUHCBQVRK-UHFFFAOYSA-N 50133183 CHEMBL3634811 D(2) dopamine receptor Rattus norvegicus 198 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196371 321903539 CHEMBL3634811 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437867 COc1ccccc1N1CCN(CCCOc2ccc(cc2)-c2nc3ccccc3o2)CC1 InChI=1S/C27H29N3O3/c1-31-26-10-5-3-8-24(26)30-18-16-29(17-19-30)15-6-20-32-22-13-11-21(12-14-22)27-28-23-7-2-4-9-25(23)33-27/h2-5,7-14H,6,15-20H2,1H3 MJHYYYGWONMZQV-UHFFFAOYSA-N 50133203 CHEMBL3634810 D(2) dopamine receptor Rattus norvegicus 467 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133203 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133203&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196370 321903540 CHEMBL3634810 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437868 C(COc1ccc(cc1)-c1nc2ccccc2o1)CN1CCC(CC1)c1nc2ccccc2s1 InChI=1S/C28H27N3O2S/c1-3-8-25-23(6-1)29-27(33-25)20-10-12-22(13-11-20)32-19-5-16-31-17-14-21(15-18-31)28-30-24-7-2-4-9-26(24)34-28/h1-4,6-13,21H,5,14-19H2 CFVAAXIVOJKSJZ-UHFFFAOYSA-N 50133208 CHEMBL3634809 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133208&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196369 321903541 CHEMBL3634809 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437869 C(COc1ccc(cc1)-c1nc2ccccc2o1)CN1CCC(CC1)c1nc2ccccc2o1 InChI=1S/C28H27N3O3/c1-3-8-25-23(6-1)29-27(33-25)20-10-12-22(13-11-20)32-19-5-16-31-17-14-21(15-18-31)28-30-24-7-2-4-9-26(24)34-28/h1-4,6-13,21H,5,14-19H2 LPQJKQOHGVKYSK-UHFFFAOYSA-N 50133209 CHEMBL3634808 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133209&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196368 321903542 CHEMBL3634808 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437870 C(COc1ccc(cc1)-c1nc2ccccc2o1)CN1CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C29H31N3O4/c1-2-7-26-25(6-1)30-29(36-26)22-10-12-23(13-11-22)33-19-5-14-31-15-17-32(18-16-31)20-24-21-34-27-8-3-4-9-28(27)35-24/h1-4,6-13,24H,5,14-21H2 LTBPWXMCJRDIKD-UHFFFAOYSA-N 50133210 CHEMBL3634807 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133210&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196367 321903543 CHEMBL3634807 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437871 C(COc1ccc(cc1)-c1nc2ccccc2o1)CN1CCN(CC1)c1ccccn1 InChI=1S/C25H26N4O2/c1-2-7-23-22(6-1)27-25(31-23)20-9-11-21(12-10-20)30-19-5-14-28-15-17-29(18-16-28)24-8-3-4-13-26-24/h1-4,6-13H,5,14-19H2 GKGJGKJYBXXPBA-UHFFFAOYSA-N 50133211 CHEMBL3634806 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133211&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196366 321903544 CHEMBL3634806 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437872 Cc1cccc(N2CCN(CCCOc3ccc(cc3)-c3nc4ccccc4o3)CC2)c1C InChI=1S/C28H31N3O2/c1-21-7-5-9-26(22(21)2)31-18-16-30(17-19-31)15-6-20-32-24-13-11-23(12-14-24)28-29-25-8-3-4-10-27(25)33-28/h3-5,7-14H,6,15-20H2,1-2H3 CLELJDWLAJNMSA-UHFFFAOYSA-N 50133212 CHEMBL3634805 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133212&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196365 321903545 CHEMBL3634805 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437873 FC(F)(F)c1cccc(c1)N1CCN(CCCOc2ccc(cc2)-c2nc3ccccc3o2)CC1 InChI=1S/C27H26F3N3O2/c28-27(29,30)21-5-3-6-22(19-21)33-16-14-32(15-17-33)13-4-18-34-23-11-9-20(10-12-23)26-31-24-7-1-2-8-25(24)35-26/h1-3,5-12,19H,4,13-18H2 PVSUEYDGEQXFQJ-UHFFFAOYSA-N 50133213 CHEMBL3634804 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133213&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196364 321903546 CHEMBL3634804 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437874 Clc1cccc(N2CCN(CCCOc3ccc(cc3)-c3nc4ccccc4o3)CC2)c1Cl InChI=1S/C26H25Cl2N3O2/c27-21-5-3-7-23(25(21)28)31-16-14-30(15-17-31)13-4-18-32-20-11-9-19(10-12-20)26-29-22-6-1-2-8-24(22)33-26/h1-3,5-12H,4,13-18H2 LQRRYCPMPKPDKI-UHFFFAOYSA-N 50133214 CHEMBL3634803 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133214&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196363 321903547 CHEMBL3634803 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437875 C(COc1ccc(cc1)-c1nc2ccccc2o1)CN1CCN(CC1)c1ccccc1 InChI=1S/C26H27N3O2/c1-2-7-22(8-3-1)29-18-16-28(17-19-29)15-6-20-30-23-13-11-21(12-14-23)26-27-24-9-4-5-10-25(24)31-26/h1-5,7-14H,6,15-20H2 QBIQXEYXJORJLM-UHFFFAOYSA-N 50133215 CHEMBL3634802 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133215&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122196362 321903548 CHEMBL3634802 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50437876 COc1ccccc1N1CCN(CCCOc2ccc(cc2)-c2nc3ccccc3[nH]2)CC1 InChI=1S/C27H30N4O2/c1-32-26-10-5-4-9-25(26)31-18-16-30(17-19-31)15-6-20-33-22-13-11-21(12-14-22)27-28-23-7-2-3-8-24(23)29-27/h2-5,7-14H,6,15-20H2,1H3,(H,28,29) WWABSSMRPUCUEJ-UHFFFAOYSA-N 50285668 2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-1H-benzoimidazole::CHEMBL313620 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1016/j.bmcl.2015.09.045 10.7270/Q26W9CW2 26483200 Huang, L; Zhang, W; Zhang, X; Yin, L; Chen, B; Song, J Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50285668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50285668&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10456040 104127239 CHEMBL313620 ZINC26571489 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50443335 CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1cccc(OC(C)=O)c-31 InChI=1S/C22H25NO3/c1-4-9-23-10-8-16-11-17(25-3)13-18-21(16)19(23)12-15-6-5-7-20(22(15)18)26-14(2)24/h5-7,11,13,19H,4,8-10,12H2,1-3H3/t19-/m1/s1 ICIICPHBNXIOKJ-LJQANCHMSA-N 50254065 CHEMBL513174::MCL-515::R(-)-2-methoxy-11-acetyloxy-N-n-propylnoraporphine D(2) dopamine receptor Rattus norvegicus 18.9 ChEMBL 10.1016/j.bmcl.2008.11.025 10.7270/Q26W99XP 19058967 Si, YG; Choi, YK; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25181482 104106432 CHEMBL513174 ZINC40896067 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50443336 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m1/s1 WZJSIHGOLMMBAL-MRXNPFEDSA-N 84636 CHEMBL27559::NPA-11-OH-R,(+) D(2) dopamine receptor Rattus norvegicus 28.5 ChEMBL 10.1016/j.bmcl.2008.11.025 10.7270/Q26W99XP 19058967 Si, YG; Choi, YK; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333842 136350736 CHEMBL27559 ZINC05833984 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50443337 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OC(C)=O)c-31 InChI=1S/C21H23NO2/c1-3-11-22-12-10-15-6-4-8-17-20(15)18(22)13-16-7-5-9-19(21(16)17)24-14(2)23/h4-9,18H,3,10-13H2,1-2H3/t18-/m1/s1 DDXVSTOHMBOXGN-GOSISDBHSA-N 50202291 Acetic acid (R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester::CHEMBL255229 D(2) dopamine receptor Rattus norvegicus 72.3 ChEMBL 10.1016/j.bmcl.2008.11.025 10.7270/Q26W99XP 19058967 Si, YG; Choi, YK; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202291&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11336218 104081868 CHEMBL255229 ZINC13985687 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50443338 CCCCC(=O)Oc1cccc2C[C@H]3N(CCC)CCc4cc(OC)cc(c34)-c12 InChI=1S/C25H31NO3/c1-4-6-10-23(27)29-22-9-7-8-17-15-21-24-18(11-13-26(21)12-5-2)14-19(28-3)16-20(24)25(17)22/h7-9,14,16,21H,4-6,10-13,15H2,1-3H3/t21-/m1/s1 MUDQDDJDUSCNJB-OAQYLSRUSA-N 50254090 CHEMBL468056::Pentanoic acid (R)-2-methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester D(2) dopamine receptor Rattus norvegicus 89 ChEMBL 10.1016/j.bmcl.2008.11.025 10.7270/Q26W99XP 19058967 Si, YG; Choi, YK; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254090&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44569492 104106448 CHEMBL468056 ZINC40395367 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50443339 COc1cc2CCN(C)[C@@H]3Cc4cccc(OC(C)=O)c4-c(c1)c23 InChI=1S/C20H21NO3/c1-12(22)24-18-6-4-5-13-10-17-19-14(7-8-21(17)2)9-15(23-3)11-16(19)20(13)18/h4-6,9,11,17H,7-8,10H2,1-3H3/t17-/m1/s1 LDYRKVDHSYMRQS-QGZVFWFLSA-N 50254064 Acetic acid (R)-2-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester::CHEMBL468677 D(2) dopamine receptor Rattus norvegicus 165 ChEMBL 10.1016/j.bmcl.2008.11.025 10.7270/Q26W99XP 19058967 Si, YG; Choi, YK; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50254064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50254064&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44569447 104106431 CHEMBL468677 ZINC40395234 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50443340 CCCCC(=O)Oc1cccc2C[C@H]3N(C)CCc4cc(OC)cc(c34)-c12 InChI=1S/C23H27NO3/c1-4-5-9-21(25)27-20-8-6-7-15-13-19-22-16(10-11-24(19)2)12-17(26-3)14-18(22)23(15)20/h6-8,12,14,19H,4-5,9-11,13H2,1-3H3/t19-/m1/s1 NMUGDOOOAXACRK-LJQANCHMSA-N 50252323 (R)-2-Methoxyaporphin-11-yl pentanoate::CHEMBL482276::MCL-516::R(-)-2-methoxy-11-valeryloxy-N-n-propylnoraporhine D(2) dopamine receptor Rattus norvegicus 192 ChEMBL 10.1016/j.bmcl.2008.11.025 10.7270/Q26W99XP 19058967 Si, YG; Choi, YK; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50252323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50252323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44593524 104105235 CHEMBL482276 ZINC40411281 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50443341 CCCCC(=O)Oc1cccc2C[C@H]3N(CCC)CCc4cccc(c34)-c12 InChI=1S/C24H29NO2/c1-3-5-12-22(26)27-21-11-7-9-18-16-20-23-17(13-15-25(20)14-4-2)8-6-10-19(23)24(18)21/h6-11,20H,3-5,12-16H2,1-2H3/t20-/m1/s1 JGCVBGVDWQJTDF-HXUWFJFHSA-N 50202292 11-valeryloxynoraporphine::CHEMBL403550::Pentanoic acid (R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester D(2) dopamine receptor Rattus norvegicus 340 ChEMBL 10.1016/j.bmcl.2008.11.025 10.7270/Q26W99XP 19058967 Si, YG; Choi, YK; Gardner, MP; Tarazi, FI; Baldessarini, RJ; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202292&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44447998 104081869 CHEMBL403550 ZINC29041617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465185 COc1ccccc1N1CCN(CCNC(=O)c2ccncc2)CC1 InChI=1S/C19H24N4O2/c1-25-18-5-3-2-4-17(18)23-14-12-22(13-15-23)11-10-21-19(24)16-6-8-20-9-7-16/h2-9H,10-15H2,1H3,(H,21,24) IQYRBWJVVBVMOS-UHFFFAOYSA-N 50056031 CHEMBL104593::N-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-isonicotinamide D(2) dopamine receptor Rattus norvegicus 537 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640907 103952437 CHEMBL104593 ZINC13760892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465186 Clc1ccccc1N1CCN(CCNC(=O)c2ccncc2)CC1 InChI=1S/C18H21ClN4O/c19-16-3-1-2-4-17(16)23-13-11-22(12-14-23)10-9-21-18(24)15-5-7-20-8-6-15/h1-8H,9-14H2,(H,21,24) VWYRKMWREYNOQH-UHFFFAOYSA-N 50145623 CHEMBL3763714 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145623&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324024 85439956 CHEMBL3763714 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465187 Clc1cccc(c1)N1CCN(CCNC(=O)c2ccncc2)CC1 InChI=1S/C18H21ClN4O/c19-16-2-1-3-17(14-16)23-12-10-22(11-13-23)9-8-21-18(24)15-4-6-20-7-5-15/h1-7,14H,8-13H2,(H,21,24) JCCYAZCVHKZJFG-UHFFFAOYSA-N 50145624 CHEMBL3764539 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145624&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324163 85440309 CHEMBL3764539 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465188 Fc1ccccc1N1CCN(CCNC(=O)c2ccncc2)CC1 InChI=1S/C18H21FN4O/c19-16-3-1-2-4-17(16)23-13-11-22(12-14-23)10-9-21-18(24)15-5-7-20-8-6-15/h1-8H,9-14H2,(H,21,24) BCVMAEDRAYTSDX-UHFFFAOYSA-N 50145627 CHEMBL3763812 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145627&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324140 85440244 CHEMBL3763812 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465189 Fc1ccc(cc1)N1CCN(CCNC(=O)c2ccncc2)CC1 InChI=1S/C18H21FN4O/c19-16-1-3-17(4-2-16)23-13-11-22(12-14-23)10-9-21-18(24)15-5-7-20-8-6-15/h1-8H,9-14H2,(H,21,24) HBRJQKKQLVXGLT-UHFFFAOYSA-N 50145628 CHEMBL3765231 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145628&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10231144 85439742 CHEMBL3765231 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465190 O=C(NCCN1CCN(CC1)c1ccccn1)c1ccncc1 InChI=1S/C17H21N5O/c23-17(15-4-7-18-8-5-15)20-9-10-21-11-13-22(14-12-21)16-3-1-2-6-19-16/h1-8H,9-14H2,(H,20,23) KTIXCJUKKFEAAE-UHFFFAOYSA-N 50145585 CHEMBL3765362 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145585&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323307 85438287 CHEMBL3765362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465196 Cl.Fc1ccc(cc1)C(N1CCN(CCNC(=O)c2ccncc2)CC1)c1ccc(F)cc1 InChI=1S/C25H26F2N4O.ClH/c26-22-5-1-19(2-6-22)24(20-3-7-23(27)8-4-20)31-17-15-30(16-18-31)14-13-29-25(32)21-9-11-28-12-10-21;/h1-12,24H,13-18H2,(H,29,32);1H BDGWDVARUQVWDY-UHFFFAOYSA-N 50145591 CHEMBL3765471 D(2) dopamine receptor Rattus norvegicus 1680 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323138 104034353 CHEMBL3765471 ZINC26578529 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465198 Cc1cccc(N2CCN(CCCNC(=O)c3ccncc3)CC2)c1C InChI=1S/C21H28N4O/c1-17-5-3-6-20(18(17)2)25-15-13-24(14-16-25)12-4-9-23-21(26)19-7-10-22-11-8-19/h3,5-8,10-11H,4,9,12-16H2,1-2H3,(H,23,26) KLSHYRCXYZZWFQ-UHFFFAOYSA-N 50145603 CHEMBL3764575 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145603&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45261023 92732865 CHEMBL3764575 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465199 Fc1ccccc1N1CCN(CCCNC(=O)c2ccncc2)CC1 InChI=1S/C19H23FN4O/c20-17-4-1-2-5-18(17)24-14-12-23(13-15-24)11-3-8-22-19(25)16-6-9-21-10-7-16/h1-2,4-7,9-10H,3,8,11-15H2,(H,22,25) KUVDBGQRAUIWGG-UHFFFAOYSA-N 50145609 CHEMBL3763474 D(2) dopamine receptor Rattus norvegicus 1420 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145609&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323897 85439609 CHEMBL3763474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465202 Fc1ccc(cc1)N1CCN(CCCNC(=O)c2ccncc2)CC1 InChI=1S/C19H23FN4O/c20-17-2-4-18(5-3-17)24-14-12-23(13-15-24)11-1-8-22-19(25)16-6-9-21-10-7-16/h2-7,9-10H,1,8,11-15H2,(H,22,25) UEQGRPBCHZRURB-UHFFFAOYSA-N 50145610 CHEMBL3764420 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145610&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9851384 85440263 CHEMBL3764420 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465203 O=C(NCCCN1CCN(CC1)c1ncccn1)c1ccncc1 InChI=1S/C17H22N6O/c24-16(15-3-8-18-9-4-15)19-7-2-10-22-11-13-23(14-12-22)17-20-5-1-6-21-17/h1,3-6,8-9H,2,7,10-14H2,(H,19,24) DGZNKZXCLRHNMR-UHFFFAOYSA-N 50145612 CHEMBL3764177 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145612&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323838 85439460 CHEMBL3764177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465205 O=C(NCCCN1CCN(Cc2ccc3OCOc3c2)CC1)c1ccncc1 InChI=1S/C21H26N4O3/c26-21(18-4-7-22-8-5-18)23-6-1-9-24-10-12-25(13-11-24)15-17-2-3-19-20(14-17)28-16-27-19/h2-5,7-8,14H,1,6,9-13,15-16H2,(H,23,26) GQPZNEKXJZVZFM-UHFFFAOYSA-N 50145613 CHEMBL3764390 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145613&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324208 85440414 CHEMBL3764390 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465216 Cl.Fc1ccc(cc1)C(N1CCN(CCCNC(=O)c2ccncc2)CC1)c1ccc(F)cc1 InChI=1S/C26H28F2N4O.ClH/c27-23-6-2-20(3-7-23)25(21-4-8-24(28)9-5-21)32-18-16-31(17-19-32)15-1-12-30-26(33)22-10-13-29-14-11-22;/h2-11,13-14,25H,1,12,15-19H2,(H,30,33);1H NWVQWEATHIBBPB-UHFFFAOYSA-N 50145616 CHEMBL3763331 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1016/j.ejmech.2016.01.021 10.7270/Q24X59N9 26820556 Fiorino, F; Ciano, A; Magli, E; Severino, B; Corvino, A; Perissutti, E; Frecentese, F; Di Vaio, P; Izzo, AA; Capasso, R; Massarelli, P; Nencini, C; Rossi, I; Kedzierska, E; Orzelska-Gòrka, J; Bielenica, A; Santagada, V; Caliendo, G Dipartimento di Farmacia Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145616&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44324138 85440240 CHEMBL3763331 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50459875 ONC(=N)CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12 InChI=1S/C17H19FN6O/c18-12-3-4-14-13(10-12)20-17(15-2-1-5-24(14)15)23-8-6-22(7-9-23)11-16(19)21-25/h1-5,10,25H,6-9,11H2,(H2,19,21) OHKKNUFVKFSRIU-UHFFFAOYSA-N 50258431 CHEMBL523716::[4-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl)piperazin-1-yl]hydroxyacetamidine D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm900018b 10.7270/Q2M908K7 19425598 Morelli, E; Gemma, S; Budriesi, R; Campiani, G; Novellino, E; Fattorusso, C; Catalanotti, B; Coccone, SS; Ros, S; Borrelli, G; Persico, M; Fiorini, I; Nacci, V; Ioan, P; Chiarini, A; Hamon, M; Cagnotto, A; Mennini, T; Fracasso, C; Colovic, M; Caccia, S; Butini, S European Research Centre for Drug Discovery and Development (NatSynDrugs) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44157734 104109114 CHEMBL523716 ZINC40953018 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50459881 N[C@@H](CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12)C(O)=O InChI=1S/C18H20FN5O2/c19-12-3-4-15-14(10-12)21-17(16-2-1-5-24(15)16)23-8-6-22(7-9-23)11-13(20)18(25)26/h1-5,10,13H,6-9,11,20H2,(H,25,26)/t13-/m0/s1 CTKOQDQPYZTIFY-ZDUSSCGKSA-N 50258462 (S)-2-Amino-3-[4-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)piperazin-1-yl]propionic Acid::CHEMBL511555 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm900018b 10.7270/Q2M908K7 19425598 Morelli, E; Gemma, S; Budriesi, R; Campiani, G; Novellino, E; Fattorusso, C; Catalanotti, B; Coccone, SS; Ros, S; Borrelli, G; Persico, M; Fiorini, I; Nacci, V; Ioan, P; Chiarini, A; Hamon, M; Cagnotto, A; Mennini, T; Fracasso, C; Colovic, M; Caccia, S; Butini, S European Research Centre for Drug Discovery and Development (NatSynDrugs) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44157942 104109134 CHEMBL511555 ZINC40401805 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50459887 N[C@H](CN1CCN(CC1)c1nc2cc(F)ccc2n2cccc12)C(O)=O InChI=1S/C18H20FN5O2/c19-12-3-4-15-14(10-12)21-17(16-2-1-5-24(15)16)23-8-6-22(7-9-23)11-13(20)18(25)26/h1-5,10,13H,6-9,11,20H2,(H,25,26)/t13-/m1/s1 CTKOQDQPYZTIFY-CYBMUJFWSA-N 50258495 (R)-2-Amino-3-[4-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)piperazin-1-yl]propionic Acid::CHEMBL466462 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm900018b 10.7270/Q2M908K7 19425598 Morelli, E; Gemma, S; Budriesi, R; Campiani, G; Novellino, E; Fattorusso, C; Catalanotti, B; Coccone, SS; Ros, S; Borrelli, G; Persico, M; Fiorini, I; Nacci, V; Ioan, P; Chiarini, A; Hamon, M; Cagnotto, A; Mennini, T; Fracasso, C; Colovic, M; Caccia, S; Butini, S European Research Centre for Drug Discovery and Development (NatSynDrugs) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44157837 104109152 CHEMBL466462 ZINC40395344 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50459892 OC(=O)CN1CCN(CC1)c1ccc2ccccc2n1 InChI=1S/C15H17N3O2/c19-15(20)11-17-7-9-18(10-8-17)14-6-5-12-3-1-2-4-13(12)16-14/h1-6H,7-11H2,(H,19,20) HCRXUFYSLPXCDW-UHFFFAOYSA-N 50258497 (4-Quinolin-2-ylpiperazin-1-yl)acetic Acid::CHEMBL468498 D(2) dopamine receptor Rattus norvegicus 919 ChEMBL 10.1021/jm900018b 10.7270/Q2M908K7 19425598 Morelli, E; Gemma, S; Budriesi, R; Campiani, G; Novellino, E; Fattorusso, C; Catalanotti, B; Coccone, SS; Ros, S; Borrelli, G; Persico, M; Fiorini, I; Nacci, V; Ioan, P; Chiarini, A; Hamon, M; Cagnotto, A; Mennini, T; Fracasso, C; Colovic, M; Caccia, S; Butini, S European Research Centre for Drug Discovery and Development (NatSynDrugs) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 715494 104109154 CHEMBL468498 ZINC22117939 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50464504 COc1cc(N)c(Cl)cc1C(=O)NC[C@H]1CCC2CCCCN2C1 InChI=1S/C18H26ClN3O2/c1-24-17-9-16(20)15(19)8-14(17)18(23)21-10-12-5-6-13-4-2-3-7-22(13)11-12/h8-9,12-13H,2-7,10-11,20H2,1H3,(H,21,23)/t12-,13?/m1/s1 VTFNJDHZVZDGIG-PZORYLMUSA-N 50280716 4-Amino-5-chloro-2-methoxy-N-[(R)-1-(octahydro-quinolizin-3-yl)methyl]-benzamide::CHEMBL15307 D(2) dopamine receptor Rattus norvegicus 3900 ChEMBL 10.1016/S0960-894X(00)80636-8 10.7270/Q28915SZ Hadley, MS; King, FD; McRitchie, B; Smith, DM; Turner, DH TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280716&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44270214 104122420 CHEMBL15307 ZINC36093036 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50462512 CN1CCC=C2[C@@H]1CCc1sc(N)nc21 InChI=1S/C11H15N3S/c1-14-6-2-3-7-8(14)4-5-9-10(7)13-11(12)15-9/h3,8H,2,4-6H2,1H3,(H2,12,13)/t8-/m0/s1 XFJSSDHKIXXJLM-QMMMGPOBSA-N 50279805 (S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-2-ylamine::CHEMBL348012 D(2) dopamine receptor Rattus norvegicus 768 ChEMBL 10.1016/S0960-894X(01)80462-5 10.7270/Q22807HM Jaen, JC; Caprathe, BW; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44367326 104121509 CHEMBL348012 ZINC05140806 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50462514 CCCN1CCC=C2[C@H]1CCc1sc(N)nc21 InChI=1S/C13H19N3S/c1-2-7-16-8-3-4-9-10(16)5-6-11-12(9)15-13(14)17-11/h4,10H,2-3,5-8H2,1H3,(H2,14,15)/t10-/m1/s1 VOPHHPYKMCJUCP-SNVBAGLBSA-N 50279806 (R)-6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-2-ylamine::CHEMBL150551 D(2) dopamine receptor Rattus norvegicus 860 ChEMBL 10.1016/S0960-894X(01)80462-5 10.7270/Q22807HM Jaen, JC; Caprathe, BW; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44367325 104121510 CHEMBL150551 ZINC13824112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50462515 CCC[N@H+]1CCC=C2[C@@H]1CCc1sc(N)nc21 InChI=1S/C13H19N3S/c1-2-7-16-8-3-4-9-10(16)5-6-11-12(9)15-13(14)17-11/h4,10H,2-3,5-8H2,1H3,(H2,14,15)/p+1/t10-/m0/s1 VOPHHPYKMCJUCP-JTQLQIEISA-O 50007572 2-Amino-6-propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-6-ium D(2) dopamine receptor Rattus norvegicus 2243 ChEMBL 10.1016/S0960-894X(01)80462-5 10.7270/Q22807HM Jaen, JC; Caprathe, BW; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325746 103920842 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50462517 CN1CCC=C2[C@H]1CCc1sc(N)nc21 InChI=1S/C11H15N3S/c1-14-6-2-3-7-8(14)4-5-9-10(7)13-11(12)15-9/h3,8H,2,4-6H2,1H3,(H2,12,13)/t8-/m1/s1 XFJSSDHKIXXJLM-MRVPVSSYSA-N 50279807 (R)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-2-ylamine::CHEMBL150523 D(2) dopamine receptor Rattus norvegicus 376 ChEMBL 10.1016/S0960-894X(01)80462-5 10.7270/Q22807HM Jaen, JC; Caprathe, BW; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 146574 104121511 CHEMBL150523 ZINC00002365 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50462521 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1016/S0960-894X(01)80462-5 10.7270/Q22807HM Jaen, JC; Caprathe, BW; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463721 CN1CCc2cc(Cl)c(O)cc2C(C1)N1CCCCC1 InChI=1S/C16H23ClN2O/c1-18-8-5-12-9-14(17)16(20)10-13(12)15(11-18)19-6-3-2-4-7-19/h9-10,15,20H,2-8,11H2,1H3 KMGQNUYJWJFJQG-UHFFFAOYSA-N 50280428 8-Chloro-3-methyl-5-piperidin-1-yl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL334650 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280428&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937722 104122132 CHEMBL334650 ZINC38344810 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463722 CN1CCc2cc(Cl)c(O)cc2C2(CCCC2)C1 InChI=1S/C15H20ClNO/c1-17-7-4-11-8-13(16)14(18)9-12(11)15(10-17)5-2-3-6-15/h8-9,18H,2-7,10H2,1H3 RRJIUBJUSZTIFV-UHFFFAOYSA-N 50280429 7-chloro-3-methyl-2,3,4,5-tetrahydrospiro[3-benzazepine-1,1'-cyclopentan]-8-ol::CHEMBL336610 D(2) dopamine receptor Rattus norvegicus 2250 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280429&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19795148 104122133 CHEMBL336610 ZINC27323718 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463723 CN1CCc2cc(Cl)c(O)cc2C(C1)C1CCCCC1 InChI=1S/C17H24ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h9-10,12,15,20H,2-8,11H2,1H3 LTQIAJAFDWMJTE-UHFFFAOYSA-N 50280430 8-Chloro-5-cyclohexyl-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL422796 D(2) dopamine receptor Rattus norvegicus 1780 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280430&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937726 104122134 CHEMBL422796 ZINC13884985 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463724 CN1CCc2cc(Cl)c(O)cc2C(CC#C)C1 InChI=1S/C14H16ClNO/c1-3-4-11-9-16(2)6-5-10-7-13(15)14(17)8-12(10)11/h1,7-8,11,17H,4-6,9H2,2H3 MJBXDMCRKLENIA-UHFFFAOYSA-N 50280431 8-Chloro-3-methyl-5-prop-2-ynyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL127843 D(2) dopamine receptor Rattus norvegicus 626 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937719 104122135 CHEMBL127843 ZINC27317409 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463727 CCCC1CN(C)CCc2cc(Cl)c(O)cc12 InChI=1S/C14H20ClNO/c1-3-4-11-9-16(2)6-5-10-7-13(15)14(17)8-12(10)11/h7-8,11,17H,3-6,9H2,1-2H3 JIBHLDTYYXSNCP-UHFFFAOYSA-N 50280434 8-Chloro-3-methyl-5-propyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL130851 D(2) dopamine receptor Rattus norvegicus 1160 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937717 104122138 CHEMBL130851 ZINC27321562 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463728 CN1CCc2cc(Cl)c(O)cc2C(C1)C1=CCCCC1 InChI=1S/C17H22ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h5,9-10,15,20H,2-4,6-8,11H2,1H3 OMWXLIIUEOVDML-UHFFFAOYSA-N 50280435 8-Chloro-5-cyclohex-1-enyl-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL131054 D(2) dopamine receptor Rattus norvegicus 1600 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280435&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10935201 104122139 CHEMBL131054 ZINC27321882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463729 CN(C)CCCC1CN(C)CCc2cc(Cl)c(O)cc12 InChI=1S/C16H25ClN2O/c1-18(2)7-4-5-13-11-19(3)8-6-12-9-15(17)16(20)10-14(12)13/h9-10,13,20H,4-8,11H2,1-3H3 TZWBHWCSLLOIOT-UHFFFAOYSA-N 50280433 8-Chloro-5-(3-dimethylamino-propyl)-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL340324 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937723 104122137 CHEMBL340324 ZINC27313364 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463730 CCSC1CN(C)CCc2cc(Cl)c(O)cc12 InChI=1S/C13H18ClNOS/c1-3-17-13-8-15(2)5-4-9-6-11(14)12(16)7-10(9)13/h6-7,13,16H,3-5,8H2,1-2H3 VVFBHNJTTAXEPI-UHFFFAOYSA-N 50280436 8-Chloro-5-ethylsulfanyl-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL338237 D(2) dopamine receptor Rattus norvegicus 2710 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937720 104122140 CHEMBL338237 ZINC27318424 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463732 CN1CCc2cc(Cl)c(O)cc2C(C1)C1CCCC1 InChI=1S/C16H22ClNO/c1-18-7-6-12-8-15(17)16(19)9-13(12)14(10-18)11-4-2-3-5-11/h8-9,11,14,19H,2-7,10H2,1H3 FAHWOYFONAIAQL-UHFFFAOYSA-N 50280437 8-Chloro-5-cyclopentyl-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL339342 D(2) dopamine receptor Rattus norvegicus 2050 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280437&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937725 104122141 CHEMBL339342 ZINC27320676 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463733 CCOC1CN(C)CCc2cc(Cl)c(O)cc12 InChI=1S/C13H18ClNO2/c1-3-17-13-8-15(2)5-4-9-6-11(14)12(16)7-10(9)13/h6-7,13,16H,3-5,8H2,1-2H3 UWJZELKDZCMKAN-UHFFFAOYSA-N 50280432 8-Chloro-5-ethoxy-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL128917 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280432&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937721 104122136 CHEMBL128917 ZINC03783397 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463737 CN1CCc2cc(Cl)c(O)cc2C(CC=C)C1 InChI=1S/C14H18ClNO/c1-3-4-11-9-16(2)6-5-10-7-13(15)14(17)8-12(10)11/h3,7-8,11,17H,1,4-6,9H2,2H3 WNPHNSBQPJWDNK-UHFFFAOYSA-N 50280439 5-Allyl-8-chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL334728 D(2) dopamine receptor Rattus norvegicus 284 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937718 104122143 CHEMBL334728 ZINC27321552 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463739 CN1CCc2cc(Cl)c(O)cc2C(C1)C1CCCC=C1 InChI=1S/C17H22ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h3,5,9-10,12,15,20H,2,4,6-8,11H2,1H3 YWMDBNUBAGRKLQ-UHFFFAOYSA-N 50280440 8-Chloro-5-cyclohex-2-enyl-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL130328 D(2) dopamine receptor Rattus norvegicus 581 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937728 104122144 CHEMBL130328 ZINC27328658 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463740 CN1CCc2cc(Cl)c(O)cc2C(C1)C1CCCCCC1 InChI=1S/C18H26ClNO/c1-20-9-8-14-10-17(19)18(21)11-15(14)16(12-20)13-6-4-2-3-5-7-13/h10-11,13,16,21H,2-9,12H2,1H3 YISAECOZKOOTOI-UHFFFAOYSA-N 50280438 8-Chloro-5-cycloheptyl-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL336532 D(2) dopamine receptor Rattus norvegicus 1190 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937727 104122142 CHEMBL336532 ZINC27328665 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463742 CN1CCc2cc(Cl)c(O)cc2C(C1)C1=CCCC1 InChI=1S/C16H20ClNO/c1-18-7-6-12-8-15(17)16(19)9-13(12)14(10-18)11-4-2-3-5-11/h4,8-9,14,19H,2-3,5-7,10H2,1H3 USNSYPNBJKRKSR-UHFFFAOYSA-N 50280441 8-Chloro-5-cyclopent-1-enyl-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL340855 D(2) dopamine receptor Rattus norvegicus 1540 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280441&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937729 104122145 CHEMBL340855 ZINC27320652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463746 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 760 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463747 CN1CCc2cc(Cl)c(O)cc2C(C1)C1C=CC=CC=C1 InChI=1S/C18H20ClNO/c1-20-9-8-14-10-17(19)18(21)11-15(14)16(12-20)13-6-4-2-3-5-7-13/h2-7,10-11,13,16,21H,8-9,12H2,1H3 MBKZTNVGBURXSW-UHFFFAOYSA-N 50280443 8-Chloro-5-cyclohepta-2,4,6-trienyl-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL128649 D(2) dopamine receptor Rattus norvegicus 1800 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937730 104122147 CHEMBL128649 ZINC27313373 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50463750 CN1CCc2cc(O)c(Cl)cc2CC1 InChI=1S/C11H14ClNO/c1-13-4-2-8-6-10(12)11(14)7-9(8)3-5-13/h6-7,14H,2-5H2,1H3 KUIFDRGVGCKHAW-UHFFFAOYSA-N 50280442 8-Chloro-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL340006 D(2) dopamine receptor Rattus norvegicus 265 ChEMBL 10.1016/S0960-894X(00)80155-9 10.7270/Q2C53KRS Chang, WK; Peters, M; Fevig, VP; Kozlowski, JA; Zhou, G; Lowe, DB; Guzik, H; McQuade, RD; Duffy, R; Coffin, VL; Berger, JG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937731 104122146 CHEMBL340006 ZINC27317402 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465941 C(CCc1ccncc1)CN1CCC(=CC1)c1ccc2ccccc2c1 InChI=1S/C24H26N2/c1-2-7-23-19-24(9-8-21(23)6-1)22-12-17-26(18-13-22)16-4-3-5-20-10-14-25-15-11-20/h1-2,6-12,14-15,19H,3-5,13,16-18H2 UFKFJODSTRHACQ-UHFFFAOYSA-N 50281499 4-[4-(4-Naphthalen-2-yl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-pyridine::CHEMBL94950 D(2) dopamine receptor Rattus norvegicus 660 ChEMBL 10.1016/S0960-894X(01)80892-1 10.7270/Q2HH6K0R Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281499&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44327702 104123173 CHEMBL94950 ZINC26673975 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465945 C(CCc1ccncc1)CN1CCC(=CC1)c1ccccc1 InChI=1S/C20H24N2/c1-2-7-19(8-3-1)20-11-16-22(17-12-20)15-5-4-6-18-9-13-21-14-10-18/h1-3,7-11,13-14H,4-6,12,15-17H2 JHVGMVBCFXYAFS-UHFFFAOYSA-N 50281498 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-pyridine::CHEMBL96777 D(2) dopamine receptor Rattus norvegicus 69.10 ChEMBL 10.1016/S0960-894X(01)80892-1 10.7270/Q2HH6K0R Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281498&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15166841 104123172 CHEMBL96777 ZINC26672883 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465946 Cc1ccc(cc1)C1=CCN(CCCCc2ccncc2)CC1 InChI=1S/C21H26N2/c1-18-5-7-20(8-6-18)21-11-16-23(17-12-21)15-3-2-4-19-9-13-22-14-10-19/h5-11,13-14H,2-4,12,15-17H2,1H3 MQSPGQTTXPUUKH-UHFFFAOYSA-N 50281502 4-[4-(4-p-Tolyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-pyridine::CHEMBL97285 D(2) dopamine receptor Rattus norvegicus 957 ChEMBL 10.1016/S0960-894X(01)80892-1 10.7270/Q2HH6K0R Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281502&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44327682 104123176 CHEMBL97285 ZINC26719862 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465948 COc1ccc(cc1)C1=CCN(CCCCc2ccncc2)CC1 InChI=1S/C21H26N2O/c1-24-21-7-5-19(6-8-21)20-11-16-23(17-12-20)15-3-2-4-18-9-13-22-14-10-18/h5-11,13-14H,2-4,12,15-17H2,1H3 PJSIDKBGHZEVKT-UHFFFAOYSA-N 50281503 4-{4-[4-(4-Methoxy-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-pyridine::CHEMBL94801 D(2) dopamine receptor Rattus norvegicus 1639 ChEMBL 10.1016/S0960-894X(01)80892-1 10.7270/Q2HH6K0R Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44327700 104123177 CHEMBL94801 ZINC26673752 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465950 C(CCc1ccncc1)CN1CCC(=CC1)c1c[nH]c2ccccc12 InChI=1S/C22H25N3/c1-2-7-22-20(6-1)21(17-24-22)19-10-15-25(16-11-19)14-4-3-5-18-8-12-23-13-9-18/h1-2,6-10,12-13,17,24H,3-5,11,14-16H2 WOVOLFXUPUQCAS-UHFFFAOYSA-N 50281505 3-[1-(4-Pyridin-4-yl-butyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-1H-indole::CHEMBL96524 D(2) dopamine receptor Rattus norvegicus 286 ChEMBL 10.1016/S0960-894X(01)80892-1 10.7270/Q2HH6K0R Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15166844 104123179 CHEMBL96524 ZINC26667815 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465953 C(CCc1ccncc1)CN1CCC(=CC1)c1cccs1 InChI=1S/C18H22N2S/c1(4-16-6-10-19-11-7-16)2-12-20-13-8-17(9-14-20)18-5-3-15-21-18/h3,5-8,10-11,15H,1-2,4,9,12-14H2 FXHUAMJZVUMXSB-UHFFFAOYSA-N 50281504 4-[4-(4-Thiophen-2-yl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-pyridine::CHEMBL97302 D(2) dopamine receptor Rattus norvegicus 496 ChEMBL 10.1016/S0960-894X(01)80892-1 10.7270/Q2HH6K0R Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281504&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15166845 104123178 CHEMBL97302 ZINC26719050 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465954 Clc1ccc(cc1)C1=CCN(CCCCc2ccncc2)CC1 InChI=1S/C20H23ClN2/c21-20-6-4-18(5-7-20)19-10-15-23(16-11-19)14-2-1-3-17-8-12-22-13-9-17/h4-10,12-13H,1-3,11,14-16H2 QSHYUCHOHNOYKS-UHFFFAOYSA-N 50281500 4-{4-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-pyridine::CHEMBL93442 D(2) dopamine receptor Rattus norvegicus 456 ChEMBL 10.1016/S0960-894X(01)80892-1 10.7270/Q2HH6K0R Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281500&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44327701 104123174 CHEMBL93442 ZINC26673969 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465955 C(CCc1ccncc1)CN1CCC(=CC1)c1ccccn1 InChI=1S/C19H23N3/c1-3-11-21-19(6-1)18-9-15-22(16-10-18)14-4-2-5-17-7-12-20-13-8-17/h1,3,6-9,11-13H,2,4-5,10,14-16H2 JRSQWUYARZZTAX-UHFFFAOYSA-N 50281501 1'-(4-Pyridin-4-yl-butyl)-1',2',3',6'-tetrahydro-[2,4']bipyridinyl::CHEMBL94844 D(2) dopamine receptor Rattus norvegicus 322 ChEMBL 10.1016/S0960-894X(01)80892-1 10.7270/Q2HH6K0R Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281501&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15166843 104123175 CHEMBL94844 ZINC26672206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50465956 Fc1ccc(cc1)C1=CCN(CCCCc2ccncc2)CC1 InChI=1S/C20H23FN2/c21-20-6-4-18(5-7-20)19-10-15-23(16-11-19)14-2-1-3-17-8-12-22-13-9-17/h4-10,12-13H,1-3,11,14-16H2 MQHLBMYDUSNRHH-UHFFFAOYSA-N 50281497 4-{4-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-pyridine::CHEMBL421195 D(2) dopamine receptor Rattus norvegicus 5305 ChEMBL 10.1016/S0960-894X(01)80892-1 10.7270/Q2HH6K0R Wustrow, DJ; Wise, LD; Pugsley, TA; Meltzer, LT; Heffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44327733 104123171 CHEMBL421195 ZINC26721301 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471903 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471904 CCCCCCCCCN1CCC[C@H]1CNC(=O)c1cc(Cl)cc2N(C)CCOc12 InChI=1S/C24H38ClN3O2/c1-3-4-5-6-7-8-9-12-28-13-10-11-20(28)18-26-24(29)21-16-19(25)17-22-23(21)30-15-14-27(22)2/h16-17,20H,3-15,18H2,1-2H3,(H,26,29)/t20-/m0/s1 OIRVABZCOMKCDZ-FQEVSTJZSA-N 50284587 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-nonyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL284027 D(2) dopamine receptor Rattus norvegicus 750 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457685 104126158 CHEMBL284027 ZINC36187752 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471909 CCCCN1CCC[C@@H]1CNC(=O)c1cc(Cl)cc2CCOc12 InChI=1S/C18H25ClN2O2/c1-2-3-7-21-8-4-5-15(21)12-20-18(22)16-11-14(19)10-13-6-9-23-17(13)16/h10-11,15H,2-9,12H2,1H3,(H,20,22)/t15-/m1/s1 NPHBQQIDTJVGJZ-OAHLLOKOSA-N 50284590 5-Chloro-2,3-dihydro-benzofuran-7-carboxylic acid ((R)-1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL22306 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284590&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457769 104126161 CHEMBL22306 ZINC28248062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471914 CCCCN1CCC[C@H]1CNC(=O)c1cc(SC)cc2N(C)CCOc12 InChI=1S/C20H31N3O2S/c1-4-5-8-23-9-6-7-15(23)14-21-20(24)17-12-16(26-3)13-18-19(17)25-11-10-22(18)2/h12-13,15H,4-11,14H2,1-3H3,(H,21,24)/t15-/m0/s1 SZKKGHLUAWSFSZ-HNNXBMFYSA-N 50284595 4-Methyl-6-methylsulfanyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL21971 D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18649736 104126166 CHEMBL21971 ZINC28248596 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471915 CCN1CCC[C@@H]1CNC(=O)c1cc(Cl)cc2N(C)C(=O)COc12 InChI=1S/C17H22ClN3O3/c1-3-21-6-4-5-12(21)9-19-17(23)13-7-11(18)8-14-16(13)24-10-15(22)20(14)2/h7-8,12H,3-6,9-10H2,1-2H3,(H,19,23)/t12-/m1/s1 DPGIUSLRHNCIMZ-GFCCVEGCSA-N 50284596 6-Chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL279292 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284596&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457756 104126167 CHEMBL279292 ZINC28244282 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471916 CCCCCCCCCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C22H37N3O4S/c1-3-4-5-6-7-8-9-14-25-15-10-11-18(25)17-24-22(26)20-16-19(30(23,27)28)12-13-21(20)29-2/h12-13,16,18H,3-11,14-15,17H2,1-2H3,(H,24,26)(H2,23,27,28)/t18-/m0/s1 BCRHIOMGOHZPSX-SFHVURJKSA-N 50284597 2-Methoxy-N-((S)-1-nonyl-pyrrolidin-2-ylmethyl)-5-sulfamoyl-benzamide::CHEMBL280912 D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284597&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15664993 104126168 CHEMBL280912 ZINC36187751 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471917 CCCCN1CCC[C@H]1CNC(=O)c1cc(Cl)cc2CCOc12 InChI=1S/C18H25ClN2O2/c1-2-3-7-21-8-4-5-15(21)12-20-18(22)16-11-14(19)10-13-6-9-23-17(13)16/h10-11,15H,2-9,12H2,1H3,(H,20,22)/t15-/m0/s1 NPHBQQIDTJVGJZ-HNNXBMFYSA-N 50284598 5-Chloro-2,3-dihydro-benzofuran-7-carboxylic acid ((S)-1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL22772 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284598&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457774 104126169 CHEMBL22772 ZINC28250098 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50469809 CCCN(CCC)C1C[C@@H](O)c2ccccc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)14-11-13-7-5-6-8-15(13)16(18)12-14/h5-8,14,16,18H,3-4,9-12H2,1-2H3/t14?,16-/m1/s1 NYBWBNYARFYGIA-BZSJEYESSA-N 50283546 (R)-3-Dipropylamino-1,2,3,4-tetrahydro-naphthalen-1-ol::CHEMBL315840 D(2) dopamine receptor Rattus norvegicus 13950 ChEMBL 10.1016/S0960-894X(01)80289-4 10.7270/Q2FQ9WJ7 Gmeiner, P; Hummel, E; Mierau, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283546&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320901 104125203 CHEMBL315840 ZINC26577839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471919 CCCCCCCCCN1CCC[C@@H]1CNC(=O)c1cc(Cl)cc2CCOc12 InChI=1S/C23H35ClN2O2/c1-2-3-4-5-6-7-8-12-26-13-9-10-20(26)17-25-23(27)21-16-19(24)15-18-11-14-28-22(18)21/h15-16,20H,2-14,17H2,1H3,(H,25,27)/t20-/m1/s1 RPMGDSWCTGGBNZ-HXUWFJFHSA-N 50284591 5-Chloro-2,3-dihydro-benzofuran-7-carboxylic acid ((R)-1-nonyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL278838 D(2) dopamine receptor Rattus norvegicus 84 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274374 104126162 CHEMBL278838 ZINC36187750 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471924 CN1CCOc2c1cc(Cl)cc2C(=O)NC[C@H]1CCCN1Cc1ccccc1 InChI=1S/C22H26ClN3O2/c1-25-10-11-28-21-19(12-17(23)13-20(21)25)22(27)24-14-18-8-5-9-26(18)15-16-6-3-2-4-7-16/h2-4,6-7,12-13,18H,5,8-11,14-15H2,1H3,(H,24,27)/t18-/m1/s1 QWVSEPFYQZBQPE-GOSISDBHSA-N 50284602 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-benzyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL22468 D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457681 104126173 CHEMBL22468 ZINC28250145 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471928 CCCCN1CCC[C@H]1CNC(=O)c1cc(Cl)cc2N(C)C(=O)COc12 InChI=1S/C19H26ClN3O3/c1-3-4-7-23-8-5-6-14(23)11-21-19(25)15-9-13(20)10-16-18(15)26-12-17(24)22(16)2/h9-10,14H,3-8,11-12H2,1-2H3,(H,21,25)/t14-/m0/s1 KNIXJTUVNQWAHS-AWEZNQCLSA-N 50284605 6-Chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL418560 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284605&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457757 104126176 CHEMBL418560 ZINC28244288 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471930 CCN1CCC[C@@H]1CNC(=O)c1cc(Cl)cc2N(C)CCOc12 InChI=1S/C17H24ClN3O2/c1-3-21-6-4-5-13(21)11-19-17(22)14-9-12(18)10-15-16(14)23-8-7-20(15)2/h9-10,13H,3-8,11H2,1-2H3,(H,19,22)/t13-/m1/s1 BKZJUXQQYKNDDO-CYBMUJFWSA-N 50284594 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL22469 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457682 104126165 CHEMBL22469 ZINC28250152 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471931 CCN1CCC[C@@H]1CNC(=O)c1cc(Cl)cc2CCOc12 InChI=1S/C16H21ClN2O2/c1-2-19-6-3-4-13(19)10-18-16(20)14-9-12(17)8-11-5-7-21-15(11)14/h8-9,13H,2-7,10H2,1H3,(H,18,20)/t13-/m1/s1 YLIBXJUYQINVGV-CYBMUJFWSA-N 50284599 5-Chloro-2,3-dihydro-benzofuran-7-carboxylic acid ((R)-1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL21680 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284599&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274590 104126170 CHEMBL21680 ZINC28245132 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471932 CCCCCCCCCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C22H37N3O4S/c1-3-4-5-6-7-8-9-14-25-15-10-11-18(25)17-24-22(26)20-16-19(30(23,27)28)12-13-21(20)29-2/h12-13,16,18H,3-11,14-15,17H2,1-2H3,(H,24,26)(H2,23,27,28)/t18-/m1/s1 BCRHIOMGOHZPSX-GOSISDBHSA-N 50284607 2-Methoxy-N-((R)-1-nonyl-pyrrolidin-2-ylmethyl)-5-sulfamoyl-benzamide::CHEMBL21940 D(2) dopamine receptor Rattus norvegicus 92 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284607&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15664994 104126178 CHEMBL21940 ZINC14254359 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471934 CSc1cc2N(C)CCOc2c(c1)C(=O)NC[C@@H]1CCCN1Cc1ccccc1 InChI=1S/C23H29N3O2S/c1-25-11-12-28-22-20(13-19(29-2)14-21(22)25)23(27)24-15-18-9-6-10-26(18)16-17-7-4-3-5-8-17/h3-5,7-8,13-14,18H,6,9-12,15-16H2,1-2H3,(H,24,27)/t18-/m0/s1 LGVVEFQWWBTSHP-SFHVURJKSA-N 50284592 4-Methyl-6-methylsulfanyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-benzyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL22835 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284592&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457680 104126163 CHEMBL22835 ZINC00601532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471937 CCCCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C17H27N3O4S/c1-3-4-9-20-10-5-6-13(20)12-19-17(21)15-11-14(25(18,22)23)7-8-16(15)24-2/h7-8,11,13H,3-6,9-10,12H2,1-2H3,(H,19,21)(H2,18,22,23)/t13-/m1/s1 OBOHWJBYXZNLJD-CYBMUJFWSA-N 50284609 CHEMBL278762::N-((R)-1-Butyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoyl-benzamide D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284609&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12771208 104126180 CHEMBL278762 ZINC13860949 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471940 CCCCN1CCC[C@@H]1CNC(=O)c1cc(Cl)cc2N(C)C(=O)COc12 InChI=1S/C19H26ClN3O3/c1-3-4-7-23-8-5-6-14(23)11-21-19(25)15-9-13(20)10-16-18(15)26-12-17(24)22(16)2/h9-10,14H,3-8,11-12H2,1-2H3,(H,21,25)/t14-/m1/s1 KNIXJTUVNQWAHS-CQSZACIVSA-N 50284601 6-Chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL282935 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457797 104126172 CHEMBL282935 ZINC28248959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471942 CCN1CCC[C@H]1CNC(=O)c1cc(Cl)cc2CCOc12 InChI=1S/C16H21ClN2O2/c1-2-19-6-3-4-13(19)10-18-16(20)14-9-12(17)8-11-5-7-21-15(11)14/h8-9,13H,2-7,10H2,1H3,(H,18,20)/t13-/m0/s1 YLIBXJUYQINVGV-ZDUSSCGKSA-N 50284589 5-Chloro-2,3-dihydro-benzofuran-7-carboxylic acid ((S)-1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL21802 D(2) dopamine receptor Rattus norvegicus 6.50 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284589&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457796 104126160 CHEMBL21802 ZINC28249475 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471950 CSc1cc2N(C)CCOc2c(c1)C(=O)NC[C@H]1CCCN1Cc1ccccc1 InChI=1S/C23H29N3O2S/c1-25-11-12-28-22-20(13-19(29-2)14-21(22)25)23(27)24-15-18-9-6-10-26(18)16-17-7-4-3-5-8-17/h3-5,7-8,13-14,18H,6,9-12,15-16H2,1-2H3,(H,24,27)/t18-/m1/s1 LGVVEFQWWBTSHP-GOSISDBHSA-N 50284608 4-Methyl-6-methylsulfanyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-benzyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL278151 D(2) dopamine receptor Rattus norvegicus 4.20 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284608&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10482024 104126179 CHEMBL278151 ZINC03813508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471954 CCN1CCC[C@H]1CNC(=O)c1cc(Cl)cc2N(C)CCOc12 InChI=1S/C17H24ClN3O2/c1-3-21-6-4-5-13(21)11-19-17(22)14-9-12(18)10-15-16(14)23-8-7-20(15)2/h9-10,13H,3-8,11H2,1-2H3,(H,19,22)/t13-/m0/s1 BKZJUXQQYKNDDO-ZDUSSCGKSA-N 50284593 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL21819 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284593&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274375 104126164 CHEMBL21819 ZINC28242076 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471957 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.5 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471969 CCCCCCCCCN1CCC[C@@H]1CNC(=O)c1cc(Cl)cc2N(C)CCOc12 InChI=1S/C24H38ClN3O2/c1-3-4-5-6-7-8-9-12-28-13-10-11-20(28)18-26-24(29)21-16-19(25)17-22-23(21)30-15-14-27(22)2/h16-17,20H,3-15,18H2,1-2H3,(H,26,29)/t20-/m1/s1 OIRVABZCOMKCDZ-HXUWFJFHSA-N 50284603 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-nonyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL22777 D(2) dopamine receptor Rattus norvegicus 690 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284603&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457684 104126174 CHEMBL22777 ZINC36093038 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471970 CCN1CCC[C@H]1CNC(=O)c1cc(Cl)cc2N(C)C(=O)COc12 InChI=1S/C17H22ClN3O3/c1-3-21-6-4-5-12(21)9-19-17(23)13-7-11(18)8-14-16(13)24-10-15(22)20(14)2/h7-8,12H,3-6,9-10H2,1-2H3,(H,19,23)/t12-/m0/s1 DPGIUSLRHNCIMZ-LBPRGKRZSA-N 50284600 6-Chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL279698 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284600&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457763 104126171 CHEMBL279698 ZINC28246176 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471973 CCCCCCCCCN1CCC[C@H]1CNC(=O)c1cc(Cl)cc2CCOc12 InChI=1S/C23H35ClN2O2/c1-2-3-4-5-6-7-8-12-26-13-9-10-20(26)17-25-23(27)21-16-19(24)15-18-11-14-28-22(18)21/h15-16,20H,2-14,17H2,1H3,(H,25,27)/t20-/m0/s1 RPMGDSWCTGGBNZ-FQEVSTJZSA-N 50284612 5-Chloro-2,3-dihydro-benzofuran-7-carboxylic acid ((S)-1-nonyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL22154 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284612&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457795 104126183 CHEMBL22154 ZINC36187753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471976 CCCCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C17H27N3O4S/c1-3-4-9-20-10-5-6-13(20)12-19-17(21)15-11-14(25(18,22)23)7-8-16(15)24-2/h7-8,11,13H,3-6,9-10,12H2,1-2H3,(H,19,21)(H2,18,22,23)/t13-/m0/s1 OBOHWJBYXZNLJD-ZDUSSCGKSA-N 50284586 CHEMBL22857::N-((S)-1-Butyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoyl-benzamide D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12771209 104126157 CHEMBL22857 ZINC13860948 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471978 CCCCN1CCCC1CNC(=O)c1cc(cc2N(C)CCOc12)S(N)(=O)=O InChI=1S/C19H30N4O4S/c1-3-4-7-23-8-5-6-14(23)13-21-19(24)16-11-15(28(20,25)26)12-17-18(16)27-10-9-22(17)2/h11-12,14H,3-10,13H2,1-2H3,(H,21,24)(H2,20,25,26) IHHMITAGSZTQGQ-UHFFFAOYSA-N 50284588 4-Methyl-6-sulfamoyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid (1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL280879 D(2) dopamine receptor Rattus norvegicus 670 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284588&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19780145 104126159 CHEMBL280879 ZINC28247790 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50469810 CCCN(CCC)C1C[C@H](O)c2ccccc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)14-11-13-7-5-6-8-15(13)16(18)12-14/h5-8,14,16,18H,3-4,9-12H2,1-2H3/t14?,16-/m0/s1 NYBWBNYARFYGIA-WMCAAGNKSA-N 50283547 (S)-3-Dipropylamino-1,2,3,4-tetrahydro-naphthalen-1-ol::CHEMBL418944 D(2) dopamine receptor Rattus norvegicus 262 ChEMBL 10.1016/S0960-894X(01)80289-4 10.7270/Q2FQ9WJ7 Gmeiner, P; Hummel, E; Mierau, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283547&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44321342 104125204 CHEMBL418944 ZINC26576106 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50469811 CCCN(CCC)C1C[C@H](O)c2ccccc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)14-11-13-7-5-6-8-15(13)16(18)12-14/h5-8,14,16,18H,3-4,9-12H2,1-2H3/t14?,16-/m0/s1 NYBWBNYARFYGIA-WMCAAGNKSA-N 50283547 (S)-3-Dipropylamino-1,2,3,4-tetrahydro-naphthalen-1-ol::CHEMBL418944 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1016/S0960-894X(01)80289-4 10.7270/Q2FQ9WJ7 Gmeiner, P; Hummel, E; Mierau, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283547&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44321342 104125204 CHEMBL418944 ZINC26576106 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50469812 CCCN(CCC)C1C[C@@H](O)c2ccccc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)14-11-13-7-5-6-8-15(13)16(18)12-14/h5-8,14,16,18H,3-4,9-12H2,1-2H3/t14?,16-/m1/s1 NYBWBNYARFYGIA-BZSJEYESSA-N 50283546 (R)-3-Dipropylamino-1,2,3,4-tetrahydro-naphthalen-1-ol::CHEMBL315840 D(2) dopamine receptor Rattus norvegicus 35.7 ChEMBL 10.1016/S0960-894X(01)80289-4 10.7270/Q2FQ9WJ7 Gmeiner, P; Hummel, E; Mierau, J TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50283546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50283546&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320901 104125203 CHEMBL315840 ZINC26577839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471982 CCCCN1CCCC1CNC(=O)c1cccc2N(C)CCOc12 InChI=1S/C19H29N3O2/c1-3-4-10-22-11-6-7-15(22)14-20-19(23)16-8-5-9-17-18(16)24-13-12-21(17)2/h5,8-9,15H,3-4,6-7,10-14H2,1-2H3,(H,20,23) OHLTTZFTUSNLCS-UHFFFAOYSA-N 50284606 4-Methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid (1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL22465 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284606&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19780185 104126177 CHEMBL22465 ZINC28247804 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471987 CCCCCCCCCN1CCC[C@H]1CNC(=O)c1cc(Cl)cc2N(C)C(=O)COc12 InChI=1S/C24H36ClN3O3/c1-3-4-5-6-7-8-9-12-28-13-10-11-19(28)16-26-24(30)20-14-18(25)15-21-23(20)31-17-22(29)27(21)2/h14-15,19H,3-13,16-17H2,1-2H3,(H,26,30)/t19-/m0/s1 YZVZOJQCZLMJMC-IBGZPJMESA-N 50284610 6-Chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-nonyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL418374 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284610&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457772 104126181 CHEMBL418374 ZINC44182117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471990 CCCCN1CCC[C@H]1CNC(=O)c1cc(Cl)cc2N(C)CCOc12 InChI=1S/C19H28ClN3O2/c1-3-4-7-23-8-5-6-15(23)13-21-19(24)16-11-14(20)12-17-18(16)25-10-9-22(17)2/h11-12,15H,3-10,13H2,1-2H3,(H,21,24)/t15-/m0/s1 AHCLBNDBOQTPGQ-HNNXBMFYSA-N 50086852 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL283528 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18649737 103985974 CHEMBL283528 ZINC28248328 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471994 CCCCN1CCC[C@@H]1CNC(=O)c1cc(Cl)cc2N(C)CCOc12 InChI=1S/C19H28ClN3O2/c1-3-4-7-23-8-5-6-15(23)13-21-19(24)16-11-14(20)12-17-18(16)25-10-9-22(17)2/h11-12,15H,3-10,13H2,1-2H3,(H,21,24)/t15-/m1/s1 AHCLBNDBOQTPGQ-OAHLLOKOSA-N 50086863 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL279729 D(2) dopamine receptor Rattus norvegicus 630 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457584 103985985 CHEMBL279729 ZINC28249164 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471996 CN1CCOc2c1cc(Cl)cc2C(=O)NC[C@@H]1CCCN1CCc1ccccc1 InChI=1S/C23H28ClN3O2/c1-26-12-13-29-22-20(14-18(24)15-21(22)26)23(28)25-16-19-8-5-10-27(19)11-9-17-6-3-2-4-7-17/h2-4,6-7,14-15,19H,5,8-13,16H2,1H3,(H,25,28)/t19-/m0/s1 ZIGNSANQGXWXBU-IBGZPJMESA-N 50086858 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-phenethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL281363 D(2) dopamine receptor Rattus norvegicus 800 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457652 103985980 CHEMBL281363 ZINC28248590 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471997 CN1CCOc2c1cc(Cl)cc2C(=O)NC[C@@H]1CCCN1Cc1ccccc1 InChI=1S/C22H26ClN3O2/c1-25-10-11-28-21-19(12-17(23)13-20(21)25)22(27)24-14-18-8-5-9-26(18)15-16-6-3-2-4-7-16/h2-4,6-7,12-13,18H,5,8-11,14-15H2,1H3,(H,24,27)/t18-/m0/s1 QWVSEPFYQZBQPE-SFHVURJKSA-N 50284604 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((S)-1-benzyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL21386 D(2) dopamine receptor Rattus norvegicus 310 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284604&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457669 104126175 CHEMBL21386 ZINC28243131 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50472000 CN1CCOc2c1cc(Cl)cc2C(=O)NC[C@H]1CCCN1CCc1ccccc1 InChI=1S/C23H28ClN3O2/c1-26-12-13-29-22-20(14-18(24)15-21(22)26)23(28)25-16-19-8-5-10-27(19)11-9-17-6-3-2-4-7-17/h2-4,6-7,14-15,19H,5,8-13,16H2,1H3,(H,25,28)/t19-/m1/s1 ZIGNSANQGXWXBU-LJQANCHMSA-N 50086862 6-Chloro-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-phenethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL279937 D(2) dopamine receptor Rattus norvegicus 57 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457651 103985984 CHEMBL279937 ZINC28248556 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50472001 CCCCCCCCCN1CCC[C@@H]1CNC(=O)c1cc(Cl)cc2N(C)C(=O)COc12 InChI=1S/C24H36ClN3O3/c1-3-4-5-6-7-8-9-12-28-13-10-11-19(28)16-26-24(30)20-14-18(25)15-21-23(20)31-17-22(29)27(21)2/h14-15,19H,3-13,16-17H2,1-2H3,(H,26,30)/t19-/m1/s1 YZVZOJQCZLMJMC-LJQANCHMSA-N 50284613 6-Chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-nonyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL21403 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284613&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274394 104126184 CHEMBL21403 ZINC43504091 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50472002 CCCCN1CCC[C@@H]1CNC(=O)c1cc(SC)cc2N(C)CCOc12 InChI=1S/C20H31N3O2S/c1-4-5-8-23-9-6-7-15(23)14-21-20(24)17-12-16(26-3)13-18-19(17)25-11-10-22(18)2/h12-13,15H,4-11,14H2,1-3H3,(H,21,24)/t15-/m1/s1 SZKKGHLUAWSFSZ-OAHLLOKOSA-N 50284611 4-Methyl-6-methylsulfanyl-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid ((R)-1-butyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL21318 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1016/0960-894X(95)00197-2 10.7270/Q2WH2PX0 Kuroita, T; Ikebe, T; Murakami, S; Takehara, S; Kawakita, T TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284611&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457668 104126182 CHEMBL21318 ZINC28246121 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481889 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C25H34N2O2/c1-28-24-14-6-10-21-20(8-5-11-22(21)24)9-7-15-26-16-18-27(19-17-26)23-12-3-4-13-25(23)29-2/h3-4,6,10,12-14,20H,5,7-9,11,15-19H2,1-2H3 INGWKGCHJJYQIB-UHFFFAOYSA-N 50033839 1-(2-Methoxy-phenyl)-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL26929 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10385977 103942087 CHEMBL26929 ZINC13740674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481893 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.7 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481896 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 117 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481897 COc1ccccc1N1CCN(CCNC(=O)c2cc(Cl)c(N)cc2OC)CC1 InChI=1S/C21H27ClN4O3/c1-28-19-6-4-3-5-18(19)26-11-9-25(10-12-26)8-7-24-21(27)15-13-16(22)17(23)14-20(15)29-2/h3-6,13-14H,7-12,23H2,1-2H3,(H,24,27) LHXBLQLSBOWGSX-UHFFFAOYSA-N 50289383 4-Amino-5-chloro-2-methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL26758 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742798 104130954 CHEMBL26758 ZINC28762199 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481899 COc1cccc(c1)C(=O)CCCCN1CCN(CC1)c1ccccc1OC InChI=1S/C23H30N2O3/c1-27-20-9-7-8-19(18-20)22(26)11-5-6-13-24-14-16-25(17-15-24)21-10-3-4-12-23(21)28-2/h3-4,7-10,12,18H,5-6,11,13-17H2,1-2H3 ZWHFVXLGTWFJQQ-UHFFFAOYSA-N 50123716 1-(3-Methoxy-phenyl)-5-[4-(2-methoxy-phenyl)-piperazin-1-yl]-pentan-1-one::CHEMBL26135 D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123716&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276170 104016128 CHEMBL26135 ZINC13493236 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481902 COc1cccc2C(CCCc12)NC(=O)CCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H33N3O3/c1-30-23-12-6-7-19-20(23)8-5-9-21(19)26-25(29)13-14-27-15-17-28(18-16-27)22-10-3-4-11-24(22)31-2/h3-4,6-7,10-12,21H,5,8-9,13-18H2,1-2H3,(H,26,29) HGOXUQUWFDSTAA-UHFFFAOYSA-N 50052563 3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propionamide::CHEMBL28063::N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propanamide D(2) dopamine receptor Rattus norvegicus 253 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740969 103949415 CHEMBL28063 ZINC13586504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481908 COc1cccc(c1)C(=O)NCCN1CCN(CC1)c1ccccc1OC InChI=1S/C21H27N3O3/c1-26-18-7-5-6-17(16-18)21(25)22-10-11-23-12-14-24(15-13-23)19-8-3-4-9-20(19)27-2/h3-9,16H,10-15H2,1-2H3,(H,22,25) LXCQKNOPMINDBU-UHFFFAOYSA-N 50068362 3-Methoxy-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL286725 D(2) dopamine receptor Rattus norvegicus 141 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068362&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406796 103962608 CHEMBL286725 ZINC53084608 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481909 COc1cccc2C(CCCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C26H36N2O2/c1-29-25-15-8-11-22-21(10-7-12-23(22)25)9-5-6-16-27-17-19-28(20-18-27)24-13-3-4-14-26(24)30-2/h3-4,8,11,13-15,21H,5-7,9-10,12,16-20H2,1-2H3 FKAHRAYTSLFRRL-UHFFFAOYSA-N 50033835 1-(2-Methoxy-phenyl)-4-[4-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperazine::CHEMBL28209 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10001519 103942083 CHEMBL28209 ZINC13740680 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481910 COc1cccc2C(CCCc12)C(=O)NCCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H33N3O3/c1-30-23-12-6-7-19-20(23)8-5-9-21(19)25(29)26-13-14-27-15-17-28(18-16-27)22-10-3-4-11-24(22)31-2/h3-4,6-7,10-12,21H,5,8-9,13-18H2,1-2H3,(H,26,29) CPGVFFIAFKTJQY-UHFFFAOYSA-N 50052573 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL26426 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740968 103949425 CHEMBL26426 ZINC13757312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481919 COc1ccccc1N1CCN(CCCNC(=O)C2CCCc3cccc(OC)c23)CC1 InChI=1S/C26H35N3O3/c1-31-23-12-4-3-11-22(23)29-18-16-28(17-19-29)15-7-14-27-26(30)21-10-5-8-20-9-6-13-24(32-2)25(20)21/h3-4,6,9,11-13,21H,5,7-8,10,14-19H2,1-2H3,(H,27,30) FQRDAWJJGHRRCG-UHFFFAOYSA-N 50289384 8-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL283211 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289384&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44276155 104130955 CHEMBL283211 ZINC28762836 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50481920 COc1cccc(c1)C(=O)CCCN1CCN(CC1)c1ccccc1OC InChI=1S/C22H28N2O3/c1-26-19-8-5-7-18(17-19)21(25)10-6-12-23-13-15-24(16-14-23)20-9-3-4-11-22(20)27-2/h3-5,7-9,11,17H,6,10,12-16H2,1-2H3 XGXUWJSIDSMGFX-UHFFFAOYSA-N 50068364 1-(3-Methoxy-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one::CHEMBL26677 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1016/S0960-894X(97)00218-7 10.7270/Q2P55NJG Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50068364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50068364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11726532 103962610 CHEMBL26677 ZINC13493235 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471013 CCCN[C@@H]1CCc2c(cccc2[C@@H]1C)C#N InChI=1S/C15H20N2/c1-3-9-17-15-8-7-14-12(10-16)5-4-6-13(14)11(15)2/h4-6,11,15,17H,3,7-9H2,1-2H3/t11-,15+/m0/s1 CZBFFLYTWBQJJK-XHDPSFHLSA-N 50284082 (5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-naphthalene-1-carbonitrile::CHEMBL161921 D(2) dopamine receptor Rattus norvegicus 16670 ChEMBL 10.1016/S0960-894X(01)80181-5 10.7270/Q2SX6D5J Haadsma-Svensson, SR; Smith, MW; Lin, CH; Duncan, JN; Sonesson, C; Wikström, H; Waters, N; Carlsson, A; Svensson, K TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284082&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44374649 104125739 CHEMBL161921 ZINC27749200 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572643 CCc1c(C)[nH]c2CC(CN3CCN(CCCC(=O)c4ccc(F)cc4)CC3)CC(=O)c12 InChI=1S/C26H34FN3O2/c1-3-22-18(2)28-23-15-19(16-25(32)26(22)23)17-30-13-11-29(12-14-30)10-4-5-24(31)20-6-8-21(27)9-7-20/h6-9,19,28H,3-5,10-17H2,1-2H3 NWIRMMHLUWBLSN-UHFFFAOYSA-N 50215258 CHEMBL163605 D(2) dopamine receptor Rattus norvegicus 282 ChEMBL 10.7270/Q2DJ5HTQ n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215258&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10455878 376071647 CHEMBL163605 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572642 CCc1c(C)[nH]c2CC(CN3CCC(CC3)C(=O)c3ccc(F)cc3)CC(=O)c12 InChI=1S/C24H29FN2O2/c1-3-20-15(2)26-21-12-16(13-22(28)23(20)21)14-27-10-8-18(9-11-27)24(29)17-4-6-19(25)7-5-17/h4-7,16,18,26H,3,8-14H2,1-2H3 RORBQRBRHNFMGK-UHFFFAOYSA-N 50215259 CHEMBL162901 D(2) dopamine receptor Rattus norvegicus 631 ChEMBL 10.7270/Q2DJ5HTQ n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215259&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9978065 376071648 CHEMBL162901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572644 CCc1c(C)[nH]c2CC(CN3CCN(CC3)c3ccccc3OC)CC(=O)c12 InChI=1S/C23H31N3O2/c1-4-18-16(2)24-19-13-17(14-21(27)23(18)19)15-25-9-11-26(12-10-25)20-7-5-6-8-22(20)28-3/h5-8,17,24H,4,9-15H2,1-3H3 WBOSTHWNFSNILI-UHFFFAOYSA-N 50409518 CHEMBL349832 D(2) dopamine receptor Rattus norvegicus 955 ChEMBL 10.7270/Q2DJ5HTQ n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10022745 163358542 CHEMBL349832 ZINC13471638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572645 CCc1c(C)[nH]c2CC(CN3CCC(CC3)c3noc4cc(F)ccc34)CC(=O)c12 InChI=1S/C24H28FN3O2/c1-3-18-14(2)26-20-10-15(11-21(29)23(18)20)13-28-8-6-16(7-9-28)24-19-5-4-17(25)12-22(19)30-27-24/h4-5,12,15-16,26H,3,6-11,13H2,1-2H3 WIEKNCZMEBFLFB-UHFFFAOYSA-N 50215260 CHEMBL163012 D(2) dopamine receptor Rattus norvegicus 91 ChEMBL 10.7270/Q2DJ5HTQ n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215260&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10431639 376071649 CHEMBL163012 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572646 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 5.0 ChEMBL 10.7270/Q2DJ5HTQ n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572648 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.7270/Q2DJ5HTQ n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50471023 CCCN(CCC)[C@@H]1CCc2c(cccc2[C@@H]1C)C#N InChI=1S/C18H26N2/c1-4-11-20(12-5-2)18-10-9-17-15(13-19)7-6-8-16(17)14(18)3/h6-8,14,18H,4-5,9-12H2,1-3H3/t14-,18+/m0/s1 MHNYNPNSLCDEFQ-KBXCAEBGSA-N 50284085 (5S,6R)-6-Dipropylamino-5-methyl-5,6,7,8-tetrahydro-naphthalene-1-carbonitrile::CHEMBL161812 D(2) dopamine receptor Rattus norvegicus 6670 ChEMBL 10.1016/S0960-894X(01)80181-5 10.7270/Q2SX6D5J Haadsma-Svensson, SR; Smith, MW; Lin, CH; Duncan, JN; Sonesson, C; Wikström, H; Waters, N; Carlsson, A; Svensson, K TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284085&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44374638 104125742 CHEMBL161812 ZINC27749771 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50480935 COc1ccccc1N1CCN(Cn2c(O)c3CCCCn3c2=O)CC1 InChI=1S/C19H26N4O3/c1-26-17-8-3-2-6-15(17)21-12-10-20(11-13-21)14-23-18(24)16-7-4-5-9-22(16)19(23)25/h2-3,6,8,24H,4-5,7,9-14H2,1H3 AQSDXGYFPPUAQZ-UHFFFAOYSA-N 50054398 2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-tetrahydro-imidazo[1,5-a]pyridine-1,3-dione::CHEMBL295168 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/0960-894X(96)00081-9 10.7270/Q2JH3M5K López-Rodríguez, ML; Morcillo, M; Rosado, M; Benhamu, B; Sanz, AM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53657171 103951048 CHEMBL295168 ZINC29403018 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50480949 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 852 ChEMBL 10.1016/0960-894X(96)00081-9 10.7270/Q2JH3M5K López-Rodríguez, ML; Morcillo, M; Rosado, M; Benhamu, B; Sanz, AM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50480964 COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3 SJDOMIRMMUGQQK-UHFFFAOYSA-N 82517 2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione::CAS_107966::CHEMBL126632::CHEMBL8618::NAN-190::NSC_107966 D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1016/0960-894X(96)00081-9 10.7270/Q2JH3M5K López-Rodríguez, ML; Morcillo, M; Rosado, M; Benhamu, B; Sanz, AM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4431 136350487 64123 CHEMBL8618CHEMBL126632 ZINC01537496 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466723 COc1ccc2OCCC(CN3CCC4(CC3)N(CNC4=O)c3ccccc3)c2c1 InChI=1S/C24H29N3O3/c1-29-20-7-8-22-21(15-20)18(9-14-30-22)16-26-12-10-24(11-13-26)23(28)25-17-27(24)19-5-3-2-4-6-19/h2-8,15,18H,9-14,16-17H2,1H3,(H,25,28) BMPFOIOFNWMANH-UHFFFAOYSA-N 50281865 8-(6-Methoxy-chroman-4-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL14499 D(2) dopamine receptor Rattus norvegicus 164 ChEMBL 10.1016/S0960-894X(00)80301-7 10.7270/Q2QV3MF5 Ennis, MD; Hoffman, RL; Lahti, RA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281865&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269606 104123539 CHEMBL14499 ZINC36248137 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466725 COc1ccc2C(CN3CCC4(CC3)N(CNC4=O)c3ccccc3)CCOc2c1 InChI=1S/C24H29N3O3/c1-29-20-7-8-21-18(9-14-30-22(21)15-20)16-26-12-10-24(11-13-26)23(28)25-17-27(24)19-5-3-2-4-6-19/h2-8,15,18H,9-14,16-17H2,1H3,(H,25,28) LPSPHNRNDAXWOT-UHFFFAOYSA-N 50281866 8-(7-Methoxy-chroman-4-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL14896 D(2) dopamine receptor Rattus norvegicus 274 ChEMBL 10.1016/S0960-894X(00)80301-7 10.7270/Q2QV3MF5 Ennis, MD; Hoffman, RL; Lahti, RA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269512 104123540 CHEMBL14896 ZINC36248141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466726 COc1cccc2OCCC(CN3CCC4(CC3)N(CNC4=O)c3ccccc3)c12 InChI=1S/C24H29N3O3/c1-29-20-8-5-9-21-22(20)18(10-15-30-21)16-26-13-11-24(12-14-26)23(28)25-17-27(24)19-6-3-2-4-7-19/h2-9,18H,10-17H2,1H3,(H,25,28) WVZTWBKXINSVHU-UHFFFAOYSA-N 50281867 8-(5-Methoxy-chroman-4-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL14349 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1016/S0960-894X(00)80301-7 10.7270/Q2QV3MF5 Ennis, MD; Hoffman, RL; Lahti, RA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269559 104123541 CHEMBL14349 ZINC36248132 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466727 COc1cccc2OCCC(CNCCCc3ccccc3)c12 InChI=1S/C20H25NO2/c1-22-18-10-5-11-19-20(18)17(12-14-23-19)15-21-13-6-9-16-7-3-2-4-8-16/h2-5,7-8,10-11,17,21H,6,9,12-15H2,1H3 SJHRGGQBEYKSMY-UHFFFAOYSA-N 50281868 (5-Methoxy-chroman-4-ylmethyl)-(3-phenyl-propyl)-amine::CHEMBL418541 D(2) dopamine receptor Rattus norvegicus 279 ChEMBL 10.1016/S0960-894X(00)80301-7 10.7270/Q2QV3MF5 Ennis, MD; Hoffman, RL; Lahti, RA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281868&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269487 104123542 CHEMBL418541 ZINC36093034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466730 COc1ccc2C(CNCCCc3ccccc3)CCOc2c1 InChI=1S/C20H25NO2/c1-22-18-9-10-19-17(11-13-23-20(19)14-18)15-21-12-5-8-16-6-3-2-4-7-16/h2-4,6-7,9-10,14,17,21H,5,8,11-13,15H2,1H3 ATXGQTCCNBGDHP-UHFFFAOYSA-N 50281870 (7-Methoxy-chroman-4-ylmethyl)-(3-phenyl-propyl)-amine::CHEMBL14867 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/S0960-894X(00)80301-7 10.7270/Q2QV3MF5 Ennis, MD; Hoffman, RL; Lahti, RA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269581 104123544 CHEMBL14867 ZINC36248145 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466733 COc1cccc2C(CN3CCC4(CC3)N(CNC4=O)c3ccccc3)CCOc12 InChI=1S/C24H29N3O3/c1-29-21-9-5-8-20-18(10-15-30-22(20)21)16-26-13-11-24(12-14-26)23(28)25-17-27(24)19-6-3-2-4-7-19/h2-9,18H,10-17H2,1H3,(H,25,28) HQDLFPOLHWHLGD-UHFFFAOYSA-N 50281869 8-(8-Methoxy-chroman-4-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL279368 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/S0960-894X(00)80301-7 10.7270/Q2QV3MF5 Ennis, MD; Hoffman, RL; Lahti, RA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269511 104123543 CHEMBL279368 ZINC40640283 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466734 COc1ccc2OCCC(CNCCCc3ccccc3)c2c1 InChI=1S/C20H25NO2/c1-22-18-9-10-20-19(14-18)17(11-13-23-20)15-21-12-5-8-16-6-3-2-4-7-16/h2-4,6-7,9-10,14,17,21H,5,8,11-13,15H2,1H3 NEFBXSSWNMJLSJ-UHFFFAOYSA-N 50281871 (6-Methoxy-chroman-4-ylmethyl)-(3-phenyl-propyl)-amine::CHEMBL277757 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/S0960-894X(00)80301-7 10.7270/Q2QV3MF5 Ennis, MD; Hoffman, RL; Lahti, RA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269582 104123545 CHEMBL277757 ZINC36248149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466737 COc1cccc2C(CNCCCc3ccccc3)CCOc12 InChI=1S/C20H25NO2/c1-22-19-11-5-10-18-17(12-14-23-20(18)19)15-21-13-6-9-16-7-3-2-4-8-16/h2-5,7-8,10-11,17,21H,6,9,12-15H2,1H3 BMTDXVFJZOZCGC-UHFFFAOYSA-N 50281872 (8-Methoxy-chroman-4-ylmethyl)-(3-phenyl-propyl)-amine::CHEMBL275247 D(2) dopamine receptor Rattus norvegicus 620 ChEMBL 10.1016/S0960-894X(00)80301-7 10.7270/Q2QV3MF5 Ennis, MD; Hoffman, RL; Lahti, RA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44269492 104123546 CHEMBL275247 ZINC36248128 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466777 C[N+](C)(C)NCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H21ClN3S/c1-21(2,3)19-10-11-20-14-6-4-5-7-16(14)22-17-9-8-13(18)12-15(17)20/h4-9,12,19H,10-11H2,1-3H3/q+1 ZVYLQFNJTFRZHF-UHFFFAOYSA-N 50281900 CHEMBL21398::N'-[2-(2-Chloro-phenothiazin-10-yl)-ethyl]-N,N,N-trimethyl-hydrazinium; iodide D(2) dopamine receptor Rattus norvegicus 4880 ChEMBL 10.1016/S0960-894X(00)80323-6 10.7270/Q26W9B00 Markovich, KM; Farooqui, T; Wallace, LJ; Uretsky, NJ; Miller, DD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281900&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457701 104123574 CHEMBL21398 ZINC28246302 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466778 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1016/S0960-894X(00)80323-6 10.7270/Q26W9B00 Markovich, KM; Farooqui, T; Wallace, LJ; Uretsky, NJ; Miller, DD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466779 C[N+](C)(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H22ClN2S/c1-21(2,3)12-6-11-20-15-7-4-5-8-17(15)22-18-10-9-14(19)13-16(18)20/h4-5,7-10,13H,6,11-12H2,1-3H3/q+1 RGKWYLVIZNCRIY-UHFFFAOYSA-N 50019879 CHEMBL279905::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-trimethyl-ammonium; iodide D(2) dopamine receptor Rattus norvegicus 8570 ChEMBL 10.1016/S0960-894X(00)80323-6 10.7270/Q26W9B00 Markovich, KM; Farooqui, T; Wallace, LJ; Uretsky, NJ; Miller, DD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019879&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9683 103930802 CHEMBL279905 ZINC01677751 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50466780 C[N+](C)(N)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H21ClN3S/c1-21(2,19)11-5-10-20-14-6-3-4-7-16(14)22-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11,19H2,1-2H3/q+1 CSUMXQFRJKILGE-UHFFFAOYSA-N 50281901 CHEMBL21564::MethanesulfonateN-[3-(2-chloro-phenothiazin-10-yl)-propyl]-N,N-dimethyl-hydrazinium D(2) dopamine receptor Rattus norvegicus 820 ChEMBL 10.1016/S0960-894X(00)80323-6 10.7270/Q26W9B00 Markovich, KM; Farooqui, T; Wallace, LJ; Uretsky, NJ; Miller, DD TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281901&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44457698 104123575 CHEMBL21564 ZINC28246294 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482171 C=CCN1CCCC(C1)\C=C\c1ccccc1 InChI=1S/C16H21N/c1-2-12-17-13-6-9-16(14-17)11-10-15-7-4-3-5-8-15/h2-5,7-8,10-11,16H,1,6,9,12-14H2/b11-10+ LFYDIFWLHBZMPF-ZHACJKMWSA-N 50289538 1-Allyl-3-((E)-styryl)-piperidine::CHEMBL39735 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289538&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353701 104131109 CHEMBL39735 ZINC29323425 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482175 C1CNCC(C1)\C=C/c1ccccc1 InChI=1S/C13H17N/c1-2-5-12(6-3-1)8-9-13-7-4-10-14-11-13/h1-3,5-6,8-9,13-14H,4,7,10-11H2/b9-8- QXTASUKXIQDRJK-HJWRWDBZSA-N 50289542 3-((Z)-Styryl)-piperidine::CHEMBL38345 D(2) dopamine receptor Rattus norvegicus 870 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289542&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44284985 104131113 CHEMBL38345 ZINC29312800 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482180 C1CCC(CC1)N1CCCC(C1)\C=C/c1ccccc1 InChI=1S/C19H27N/c1-3-8-17(9-4-1)13-14-18-10-7-15-20(16-18)19-11-5-2-6-12-19/h1,3-4,8-9,13-14,18-19H,2,5-7,10-12,15-16H2/b14-13- UWNYFNPDMLMEHC-YPKPFQOOSA-N 50289539 1-Cyclohexyl-3-((Z)-styryl)-piperidine::CHEMBL39806 D(2) dopamine receptor Rattus norvegicus 1120 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289539&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285044 104131110 CHEMBL39806 ZINC29326269 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482182 CC(C)=CCN1CCCC(C1)\C=C\c1ccccc1 InChI=1S/C18H25N/c1-16(2)12-14-19-13-6-9-18(15-19)11-10-17-7-4-3-5-8-17/h3-5,7-8,10-12,18H,6,9,13-15H2,1-2H3/b11-10+ YRIVOKPRESAZEC-ZHACJKMWSA-N 50289546 1-(3-Methyl-but-2-enyl)-3-((E)-styryl)-piperidine::CHEMBL38848 D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289546&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285576 104131117 CHEMBL38848 ZINC29336189 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482183 C1CNCC(C1)\C=C\c1ccccc1 InChI=1S/C13H17N/c1-2-5-12(6-3-1)8-9-13-7-4-10-14-11-13/h1-3,5-6,8-9,13-14H,4,7,10-11H2/b9-8+ QXTASUKXIQDRJK-CMDGGOBGSA-N 50289548 3-((E)-Styryl)-piperidine::CHEMBL40056 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285562 104131119 CHEMBL40056 ZINC29325501 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482185 C1CCC(CC1)N1CCCC(C1)\C=C\c1ccccc1 InChI=1S/C19H27N/c1-3-8-17(9-4-1)13-14-18-10-7-15-20(16-18)19-11-5-2-6-12-19/h1,3-4,8-9,13-14,18-19H,2,5-7,10-12,15-16H2/b14-13+ UWNYFNPDMLMEHC-BUHFOSPRSA-N 50289549 1-Cyclohexyl-3-((E)-styryl)-piperidine::CHEMBL291228 D(2) dopamine receptor Rattus norvegicus 5120 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285575 104131120 CHEMBL291228 ZINC29328556 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482186 C(CN1CCCC(C1)\C=C\c1ccccc1)Cc1ccccc1 InChI=1S/C22H27N/c1-3-9-20(10-4-1)13-7-17-23-18-8-14-22(19-23)16-15-21-11-5-2-6-12-21/h1-6,9-12,15-16,22H,7-8,13-14,17-19H2/b16-15+ ACBCMYMOZJAEDD-FOCLMDBBSA-N 50289541 1-(3-Phenyl-propyl)-3-((E)-styryl)-piperidine::CHEMBL37661 D(2) dopamine receptor Rattus norvegicus 1240 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289541&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44284723 104131112 CHEMBL37661 ZINC29310502 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482187 C(CN1CCCC(C1)\C=C/c1ccccc1)Cc1ccccc1 InChI=1S/C22H27N/c1-3-9-20(10-4-1)13-7-17-23-18-8-14-22(19-23)16-15-21-11-5-2-6-12-21/h1-6,9-12,15-16,22H,7-8,13-14,17-19H2/b16-15- ACBCMYMOZJAEDD-NXVVXOECSA-N 50289537 1-(3-Phenyl-propyl)-3-((Z)-styryl)-piperidine::CHEMBL39483 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289537&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285034 104131108 CHEMBL39483 ZINC29327005 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482189 C(CCc1ccccc1)CN1CCCC(C1)\C=C/c1ccccc1 InChI=1S/C23H29N/c1-3-10-21(11-4-1)14-7-8-18-24-19-9-15-23(20-24)17-16-22-12-5-2-6-13-22/h1-6,10-13,16-17,23H,7-9,14-15,18-20H2/b17-16- IRWSTPPEWQMKSY-MSUUIHNZSA-N 50289551 1-(4-Phenyl-butyl)-3-((Z)-styryl)-piperidine::CHEMBL39818 D(2) dopamine receptor Rattus norvegicus 1440 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289551&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285013 104131122 CHEMBL39818 ZINC29322606 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482191 CC(C)=CCN1CCCC(C1)\C=C/c1ccccc1 InChI=1S/C18H25N/c1-16(2)12-14-19-13-6-9-18(15-19)11-10-17-7-4-3-5-8-17/h3-5,7-8,10-12,18H,6,9,13-15H2,1-2H3/b11-10- YRIVOKPRESAZEC-KHPPLWFESA-N 50289552 1-(3-Methyl-but-2-enyl)-3-((Z)-styryl)-piperidine::CHEMBL40031 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289552&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285043 104131123 CHEMBL40031 ZINC29326261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482194 C(Cc1ccccc1)N1CCCC(C1)\C=C\c1ccccc1 InChI=1S/C21H25N/c1-3-8-19(9-4-1)13-14-21-12-7-16-22(18-21)17-15-20-10-5-2-6-11-20/h1-6,8-11,13-14,21H,7,12,15-18H2/b14-13+ YKCREYMJRACNJN-BUHFOSPRSA-N 50289547 1-Phenethyl-3-((E)-styryl)-piperidine::CHEMBL287937 D(2) dopamine receptor Rattus norvegicus 2400 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289547&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44284724 104131118 CHEMBL287937 ZINC29310514 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482199 C(Cc1ccccc1)N1CCCC(C1)\C=C/c1ccccc1 InChI=1S/C21H25N/c1-3-8-19(9-4-1)13-14-21-12-7-16-22(18-21)17-15-20-10-5-2-6-11-20/h1-6,8-11,13-14,21H,7,12,15-18H2/b14-13- YKCREYMJRACNJN-YPKPFQOOSA-N 50289553 1-Phenethyl-3-((Z)-styryl)-piperidine::CHEMBL36979 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289553&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285030 104131124 CHEMBL36979 ZINC29322861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482203 C(CN1CCCC(C1)\C=C/c1ccccc1)C1CCCCC1 InChI=1S/C21H31N/c1-3-8-19(9-4-1)13-14-21-12-7-16-22(18-21)17-15-20-10-5-2-6-11-20/h1,3-4,8-9,13-14,20-21H,2,5-7,10-12,15-18H2/b14-13- RWNKMTZPBWQHPR-YPKPFQOOSA-N 50289545 1-(2-Cyclohexyl-ethyl)-3-((Z)-styryl)-piperidine::CHEMBL39807 D(2) dopamine receptor Rattus norvegicus 5440 ChEMBL 10.1016/S0960-894X(97)00253-9 10.7270/Q2N58MCN Mantegani, S; Brambilla, E; Cremonesi, P; Caccia, C; Fornaretto, MG; Carfagna, N; Colombo, M; McArthur, RA; Varasi, M TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285045 104131116 CHEMBL39807 ZINC29326278 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50477008 CN1CCc2cc(Cl)c(O)cc2C(C1)c1cccc(c1)N=C=S InChI=1S/C18H17ClN2OS/c1-21-6-5-13-8-17(19)18(22)9-15(13)16(10-21)12-3-2-4-14(7-12)20-11-23/h2-4,7-9,16,22H,5-6,10H2,1H3 WTWCYPGMQVAHAF-UHFFFAOYSA-N 50287046 8-Chloro-5-(3-isothiocyanato-phenyl)-3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::AS-300::CHEMBL279634 D(2) dopamine receptor Rattus norvegicus 978 ChEMBL 10.1016/0960-894X(96)00186-2 10.7270/Q2BP02R9 Archer, S; Glick, SD; Maisonneuve, IM; Bidlack, JM; Xu, JY; Teitler, M; Sebastian, A; El-Hamouly, W; Hutchinson, I TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50287046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50287046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9819535 104128617 CHEMBL279634 ZINC04631278 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572640 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.7270/Q2DJ5HTQ n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482682 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCC(O)C2)CC1 InChI=1S/C26H35N3O3/c1-20(2)32-25-11-4-3-10-24(25)28-15-13-27(14-16-28)18-21-7-5-8-22(17-21)26(31)29-12-6-9-23(30)19-29/h3-5,7-8,10-11,17,20,23,30H,6,9,12-16,18-19H2,1-2H3 QIJBSROVPILMNU-UHFFFAOYSA-N 50289780 (3-Hydroxy-piperidin-1-yl)-{3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL58053 D(2) dopamine receptor Rattus norvegicus 8.8 ChEMBL 10.1016/S0960-894X(97)00336-3 10.7270/Q2SQ90CB Reitz, AB; McDonnell, ME; Baxter, EW; Codd, EE; Wu, WN TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289780&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300869 104131351 CHEMBL58053 ZINC29564723 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482685 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-12-5-4-11-24(25)28-17-15-27(16-18-28)20-22-9-8-10-23(19-22)26(30)29-13-6-3-7-14-29/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3 ZKZFPRUSWCYSGT-UHFFFAOYSA-N 50029257 (3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)phenyl)(piperidin-1-yl)methanone::CHEMBL10085::RWJ-377796::mazapertine::{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1016/S0960-894X(97)00336-3 10.7270/Q2SQ90CB Reitz, AB; McDonnell, ME; Baxter, EW; Codd, EE; Wu, WN TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60820 103938328 CHEMBL10085 ZINC52956332 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482687 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2O)CC1 InChI=1S/C26H35N3O3/c1-20(2)32-24-11-4-3-10-23(24)28-16-14-27(15-17-28)19-21-8-7-9-22(18-21)26(31)29-13-6-5-12-25(29)30/h3-4,7-11,18,20,25,30H,5-6,12-17,19H2,1-2H3 DTUCCDRFZFVGSC-UHFFFAOYSA-N 50289781 (2-Hydroxy-piperidin-1-yl)-{3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL58517 D(2) dopamine receptor Rattus norvegicus 9 ChEMBL 10.1016/S0960-894X(97)00336-3 10.7270/Q2SQ90CB Reitz, AB; McDonnell, ME; Baxter, EW; Codd, EE; Wu, WN TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289781&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44301057 104131352 CHEMBL58517 ZINC29567213 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50482689 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCC(O)CC2)CC1 InChI=1S/C26H35N3O3/c1-20(2)32-25-9-4-3-8-24(25)28-16-14-27(15-17-28)19-21-6-5-7-22(18-21)26(31)29-12-10-23(30)11-13-29/h3-9,18,20,23,30H,10-17,19H2,1-2H3 QOPODAWBTQRJNF-UHFFFAOYSA-N 50289782 (4-Hydroxy-piperidin-1-yl)-{3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL61096 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1016/S0960-894X(97)00336-3 10.7270/Q2SQ90CB Reitz, AB; McDonnell, ME; Baxter, EW; Codd, EE; Wu, WN TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50289782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50289782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10343035 104131353 CHEMBL61096 ZINC29563855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485060 CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C InChI=1S/C18H29NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-9,14,17H,5-6,10-13H2,1-4H3/t14-,17+/m0/s1 BTOJYCTUJJHANF-WMLDXEAASA-N 50041961 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL278751::UH-232 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1016/S0960-894X(97)10068-3 10.7270/Q2F47P56 Stjernlöf, P; Lin, CH; Sonesson, C; Svensson, K; Smith, MW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604756 103973640 CHEMBL278751 ZINC03995702 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485064 CCCN1CC[C@@H]2[C@H]1CCc1cccc(O)c21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-13(16)7-6-11-4-3-5-14(17)15(11)12/h3-5,12-13,17H,2,6-10H2,1H3/t12-,13-/m1/s1 UVOXCNCVSFLEPX-CHWSQXEVSA-N 50034342 (3aR,9bS) 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::(3aR,9bS)-3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::(3aS,9bR) 3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::(Recemic)3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-9-ol::CHEMBL430332 D(2) dopamine receptor Rattus norvegicus 769 ChEMBL 10.1016/S0960-894X(97)10068-3 10.7270/Q2F47P56 Stjernlöf, P; Lin, CH; Sonesson, C; Svensson, K; Smith, MW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014136 103942543 CHEMBL430332 ZINC13826515 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485065 CCCN(CCC)C1CCc2ccc3ccoc3c2C1 InChI=1S/C18H25NO/c1-3-10-19(11-4-2)16-8-7-14-5-6-15-9-12-20-18(15)17(14)13-16/h5-6,9,12,16H,3-4,7-8,10-11,13H2,1-2H3 VFZOPLQXSQRUHM-UHFFFAOYSA-N 50290664 CHEMBL93186::Dipropyl-(6,7,8,9-tetrahydro-naphtho[1,2-b]furan-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1016/S0960-894X(97)10068-3 10.7270/Q2F47P56 Stjernlöf, P; Lin, CH; Sonesson, C; Svensson, K; Smith, MW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290664&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333405 104132216 CHEMBL93186 ZINC26663096 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485066 CCCN(CCC)C1CCc2c(C1)ccc1ccoc21 InChI=1S/C18H25NO/c1-3-10-19(11-4-2)16-7-8-17-15(13-16)6-5-14-9-12-20-18(14)17/h5-6,9,12,16H,3-4,7-8,10-11,13H2,1-2H3 GISUIIBROMOYGQ-UHFFFAOYSA-N 50290665 CHEMBL96735::Dipropyl-(6,7,8,9-tetrahydro-naphtho[1,2-b]furan-7-yl)-amine D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1016/S0960-894X(97)10068-3 10.7270/Q2F47P56 Stjernlöf, P; Lin, CH; Sonesson, C; Svensson, K; Smith, MW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290665&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19041559 104132217 CHEMBL96735 ZINC13905628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485072 CCCN(CCC)[C@@H]1CCc2c(ccc3ccoc23)[C@@H]1C InChI=1S/C19H27NO/c1-4-11-20(12-5-2)18-9-8-17-16(14(18)3)7-6-15-10-13-21-19(15)17/h6-7,10,13-14,18H,4-5,8-9,11-12H2,1-3H3/t14-,18+/m0/s1 BIWLJQPOPQOPKB-KBXCAEBGSA-N 50133917 ((6S,7R)-6-Methyl-6,7,8,9-tetrahydro-naphtho[1,2-b]furan-7-yl)-dipropyl-amine::CHEMBL433002 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1016/S0960-894X(97)10068-3 10.7270/Q2F47P56 Stjernlöf, P; Lin, CH; Sonesson, C; Svensson, K; Smith, MW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44326256 104024622 CHEMBL433002 ZINC13527710 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485075 CCCN(CCC)C1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3 MDBWEQVKJDMEMK-UHFFFAOYSA-N 50020221 (-)-5-hydroxy-2-(dipropylamino)tetralin::(-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::5-hydroxy-2-(dipropylamino)tetralin::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (DP-5-ADTN)::CHEMBL273273 D(2) dopamine receptor Rattus norvegicus 0.700000 ChEMBL 10.1016/S0960-894X(97)10068-3 10.7270/Q2F47P56 Stjernlöf, P; Lin, CH; Sonesson, C; Svensson, K; Smith, MW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 172267 103931135 CHEMBL273273 128 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485083 CCCN1CC[C@@H]2[C@H]1CCc1ccc3ccoc3c21 InChI=1S/C17H21NO/c1-2-9-18-10-7-14-15(18)6-5-12-3-4-13-8-11-19-17(13)16(12)14/h3-4,8,11,14-15H,2,5-7,9-10H2,1H3/t14-,15-/m1/s1 ASNREPVWGRJPSG-HUUCEWRRSA-N 50290663 (7aR,10aS)-8-Propyl-7,7a,8,9,10,10a-hexahydro-6H-1-oxa-8-aza-dicyclopenta[a,h]naphthalene::CHEMBL328107 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1016/S0960-894X(97)10068-3 10.7270/Q2F47P56 Stjernlöf, P; Lin, CH; Sonesson, C; Svensson, K; Smith, MW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290663&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44326324 104132215 CHEMBL328107 ZINC26662848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485086 CCCN(CCC)C1CCc2ccc3occc3c2C1 InChI=1S/C18H25NO/c1-3-10-19(11-4-2)15-7-5-14-6-8-18-16(9-12-20-18)17(14)13-15/h6,8-9,12,15H,3-5,7,10-11,13H2,1-2H3 NBMBMTFMWYKPHV-UHFFFAOYSA-N 50290666 CHEMBL314548::Dipropyl-(6,7,8,9-tetrahydro-naphtho[2,1-b]furan-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1016/S0960-894X(97)10068-3 10.7270/Q2F47P56 Stjernlöf, P; Lin, CH; Sonesson, C; Svensson, K; Smith, MW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290666&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44326257 104132218 CHEMBL314548 ZINC26664525 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485087 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1016/S0960-894X(97)10068-3 10.7270/Q2F47P56 Stjernlöf, P; Lin, CH; Sonesson, C; Svensson, K; Smith, MW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485091 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 2.5 ChEMBL 10.1016/S0960-894X(97)10068-3 10.7270/Q2F47P56 Stjernlöf, P; Lin, CH; Sonesson, C; Svensson, K; Smith, MW TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50492748 CCCN(CCC)C1CCc2ccc3cc[nH]c3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)16-8-7-14-5-6-15-9-10-19-18(15)17(14)13-16/h5-6,9-10,16,19H,3-4,7-8,11-13H2,1-2H3 MCMMNBMKDJGGIV-UHFFFAOYSA-N 50037274 CHEMBL308143::Dipropyl-(6,7,8,9-tetrahydro-1H-benzo[g]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 145 ChEMBL 10.1021/jm00046a010 10.7270/Q21R6PJ7 7932553 Stjernlof, P; Elebring, T; Nilsson, J; Andersson, B; Lagerkvist, S; Svensson, K; Ekman, A; Carlsson, A; Wikstrom, H Göteborg University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037274&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10107188 103944822 CHEMBL308143 ZINC13738691 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484718 COc1ccccc1N1CCN(CCCc2ccc3n(CCN4CCC(CC4)C(=O)c4ccc(F)cc4)c(=O)sc3c2)CC1 InChI=1S/C35H41FN4O3S/c1-43-32-7-3-2-6-30(32)39-22-19-37(20-23-39)16-4-5-26-8-13-31-33(25-26)44-35(42)40(31)24-21-38-17-14-28(15-18-38)34(41)27-9-11-29(36)12-10-27/h2-3,6-13,25,28H,4-5,14-24H2,1H3 LZVZRPUWGPOYBB-UHFFFAOYSA-N 50290505 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-6-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-3H-benzothiazol-2-one::CHEMBL87469 D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320588 104132057 CHEMBL87469 ZINC26575107 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484719 Fc1ccc(cc1)C(=O)C1CCN(CCN2C(=O)OCc3cc(CCCCN4CCOCC4)ccc23)CC1 InChI=1S/C30H38FN3O4/c31-27-7-5-24(6-8-27)29(35)25-10-13-33(14-11-25)15-16-34-28-9-4-23(21-26(28)22-38-30(34)36)3-1-2-12-32-17-19-37-20-18-32/h4-9,21,25H,1-3,10-20,22H2 JDZYVIOTRKFEGM-UHFFFAOYSA-N 50290506 1-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-6-(4-morpholin-4-yl-butyl)-1,4-dihydro-benzo[d][1,3]oxazin-2-one::CHEMBL312982 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290506&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320426 104132058 CHEMBL312982 ZINC26575960 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485703 CCCN1CCC(C1)c1cccc(c1)S(C)(=O)=O InChI=1S/C14H21NO2S/c1-3-8-15-9-7-13(11-15)12-5-4-6-14(10-12)18(2,16)17/h4-6,10,13H,3,7-9,11H2,1-2H3 RJYDYJIGFDPBRL-UHFFFAOYSA-N 50290926 3-(3-Methanesulfonyl-phenyl)-1-propyl-pyrrolidine::CHEMBL310745 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290926&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461148 104132478 CHEMBL310745 ZINC26496921 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485715 CCCN1CCC(C1)c1cccc(c1)C(F)(F)F InChI=1S/C14H18F3N/c1-2-7-18-8-6-12(10-18)11-4-3-5-13(9-11)14(15,16)17/h3-5,9,12H,2,6-8,10H2,1H3 YATKXAPVZGTXAR-UHFFFAOYSA-N 50290929 1-Propyl-3-(3-trifluoromethyl-phenyl)-pyrrolidine::CHEMBL310607 D(2) dopamine receptor Rattus norvegicus 151 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290929&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44460502 104132481 CHEMBL310607 ZINC26488883 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485718 C1CC(CN1)c1cccc2ccccc12 InChI=1S/C14H15N/c1-2-6-13-11(4-1)5-3-7-14(13)12-8-9-15-10-12/h1-7,12,15H,8-10H2 KTMCVZGLGDBGJZ-UHFFFAOYSA-N 50290933 3-Naphthalen-1-yl-pyrrolidine::CHEMBL311972 D(2) dopamine receptor Rattus norvegicus 264 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290933&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10584082 104132485 CHEMBL311972 ZINC26493216 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485719 C1CC(CN1)c1ccccc1 InChI=1S/C10H13N/c1-2-4-9(5-3-1)10-6-7-11-8-10/h1-5,10-11H,6-8H2 PRRFFTYUBPGHLE-UHFFFAOYSA-N 50144660 3-Phenyl-pyrrolidine::CHEMBL75207 D(2) dopamine receptor Rattus norvegicus 486 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50144660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50144660&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3146743 104033733 CHEMBL75207 ZINC01237308 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485722 CCCN1CCC(C1)c1cccc(OS(=O)(=O)C(F)(F)F)c1 InChI=1S/C14H18F3NO3S/c1-2-7-18-8-6-12(10-18)11-4-3-5-13(9-11)21-22(19,20)14(15,16)17/h3-5,9,12H,2,6-8,10H2,1H3 MVBKJLXZIXBXKY-UHFFFAOYSA-N 50290928 CHEMBL79812::Trifluoro-methanesulfonic acid 3-(1-propyl-pyrrolidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 162 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290928&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44460777 104132480 CHEMBL79812 ZINC36187783 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485724 CCCN1CCC(C1)c1cccc2ccccc12 InChI=1S/C17H21N/c1-2-11-18-12-10-15(13-18)17-9-5-7-14-6-3-4-8-16(14)17/h3-9,15H,2,10-13H2,1H3 JPGGRFYDEHKZFB-UHFFFAOYSA-N 50290927 3-Naphthalen-1-yl-1-propyl-pyrrolidine::CHEMBL82485 D(2) dopamine receptor Rattus norvegicus 71 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290927&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44460743 104132479 CHEMBL82485 ZINC26492745 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485727 CCCN1CCC(C1)c1cccnc1 InChI=1S/C12H18N2/c1-2-7-14-8-5-12(10-14)11-4-3-6-13-9-11/h3-4,6,9,12H,2,5,7-8,10H2,1H3 UIWBBOCIFDQWIF-UHFFFAOYSA-N 50290934 3-(1-Propyl-pyrrolidin-3-yl)-pyridine::CHEMBL311378 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290934&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461147 104132486 CHEMBL311378 ZINC26496912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485734 CCCN1CCC(C1)C1CCCCC1 InChI=1S/C13H25N/c1-2-9-14-10-8-13(11-14)12-6-4-3-5-7-12/h12-13H,2-11H2,1H3 UMDPCWOWMSWVNT-UHFFFAOYSA-N 50290932 3-Cyclohexyl-1-propyl-pyrrolidine::CHEMBL81623 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290932&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44460756 104132484 CHEMBL81623 ZINC26489730 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485735 CCCN1CCC(C1)c1ccccc1 InChI=1S/C13H19N/c1-2-9-14-10-8-13(11-14)12-6-4-3-5-7-12/h3-7,13H,2,8-11H2,1H3 SUMWVMTWESCBLU-UHFFFAOYSA-N 50290930 3-Phenyl-1-propyl-pyrrolidine::CHEMBL82541 D(2) dopamine receptor Rattus norvegicus 625 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12101308 104132482 CHEMBL82541 ZINC26492752 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485736 CCCN1CCC(C1)c1cccc(O)c1 InChI=1S/C13H19NO/c1-2-7-14-8-6-12(10-14)11-4-3-5-13(15)9-11/h3-5,9,12,15H,2,6-8,10H2,1H3 WPYVGSUSOOZONM-UHFFFAOYSA-N 50290931 3-(1-Propyl-pyrrolidin-3-yl)-phenol::CHEMBL81675 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290931&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11074524 104132483 CHEMBL81675 ZINC26489721 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50485741 CN1CCC(C1)C1=CN=CCC1 InChI=1S/C10H16N2/c1-12-6-4-10(8-12)9-3-2-5-11-7-9/h5,7,10H,2-4,6,8H2,1H3 GWBIBWHPIKQCCD-UHFFFAOYSA-N 50290935 5-(1-Methyl-pyrrolidin-3-yl)-3,4-dihydro-pyridine::CHEMBL81665 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290935&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44460721 104132487 CHEMBL81665 ZINC26489425 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484728 COc1ccccc1N1CCN(CCc2ccc3n(CCN4CCC(CC4)C(=O)c4ccc(F)cc4)c(=O)sc3c2)CC1 InChI=1S/C34H39FN4O3S/c1-42-31-5-3-2-4-29(31)38-21-18-37(19-22-38)15-12-25-6-11-30-32(24-25)43-34(41)39(30)23-20-36-16-13-27(14-17-36)33(40)26-7-9-28(35)10-8-26/h2-11,24,27H,12-23H2,1H3 COOVPPBNHHFYDF-UHFFFAOYSA-N 50290510 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-6-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-3H-benzothiazol-2-one::CHEMBL314814 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19437824 104132062 CHEMBL314814 ZINC26575961 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484737 COc1ccccc1N1CCN(CCCCc2ccc3n(CCN4CCC(CC4)=C(c4ccc(F)cc4)c4ccc(F)cc4)c(=O)sc3c2)CC1 InChI=1S/C42H46F2N4O2S/c1-50-39-8-3-2-7-37(39)47-27-24-45(25-28-47)21-5-4-6-31-9-18-38-40(30-31)51-42(49)48(38)29-26-46-22-19-34(20-23-46)41(32-10-14-35(43)15-11-32)33-12-16-36(44)17-13-33/h2-3,7-18,30H,4-6,19-29H2,1H3 WOHUDPBPWKPSAX-UHFFFAOYSA-N 50290512 3-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-6-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-3H-benzothiazol-2-one::CHEMBL314371 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290512&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320689 104132064 CHEMBL314371 ZINC26577112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484740 COc1ccccc1N1CCN(CCCCc2ccc3n(CCN4CCC(CC4)C(=O)c4ccc(F)cc4)c(=O)oc3c2)CC1 InChI=1S/C36H43FN4O4/c1-44-33-8-3-2-7-31(33)40-23-20-38(21-24-40)17-5-4-6-27-9-14-32-34(26-27)45-36(43)41(32)25-22-39-18-15-29(16-19-39)35(42)28-10-12-30(37)13-11-28/h2-3,7-14,26,29H,4-6,15-25H2,1H3 SMKCWLRQAIMCBO-UHFFFAOYSA-N 50290515 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-6-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-3H-benzooxazol-2-one::CHEMBL314372 D(2) dopamine receptor Rattus norvegicus 0.500000 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19437835 104132067 CHEMBL314372 ZINC26577113 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484745 COc1ccccc1N1CCN(CCCCc2ccc3N(CCN4CCC(CC4)=C(c4ccc(F)cc4)c4ccc(F)cc4)C(=O)OCc3c2)CC1 InChI=1S/C43H48F2N4O3/c1-51-41-8-3-2-7-40(41)48-27-24-46(25-28-48)21-5-4-6-32-9-18-39-36(30-32)31-52-43(50)49(39)29-26-47-22-19-35(20-23-47)42(33-10-14-37(44)15-11-33)34-12-16-38(45)17-13-34/h2-3,7-18,30H,4-6,19-29,31H2,1H3 KJJPRLXHLHFGRW-UHFFFAOYSA-N 50290509 1-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-6-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-1,4-dihydro-benzo[d][1,3]oxazin-2-one::CHEMBL313744 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320688 104132061 CHEMBL313744 ZINC26576187 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484749 COc1ccccc1N1CCN(CCCCc2ccc3N(CCN4CCC(CC4)C(=O)c4ccc(F)cc4)C(=O)OCc3c2)CC1 InChI=1S/C37H45FN4O4/c1-45-35-8-3-2-7-34(35)41-23-20-39(21-24-41)17-5-4-6-28-9-14-33-31(26-28)27-46-37(44)42(33)25-22-40-18-15-30(16-19-40)36(43)29-10-12-32(38)13-11-29/h2-3,7-14,26,30H,4-6,15-25,27H2,1H3 WIUSLLLTFQPYHM-UHFFFAOYSA-N 50290513 1-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-6-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-1,4-dihydro-benzo[d][1,3]oxazin-2-one::CHEMBL85580 D(2) dopamine receptor Rattus norvegicus 0.060000 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320417 104132065 CHEMBL85580 ZINC26573916 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484755 COc1ccccc1N1CCN(CCCCc2ccc3n(CCN4CCC(CC4)=C(c4ccc(F)cc4)c4ccc(F)cc4)c(=O)oc3c2)CC1 InChI=1S/C42H46F2N4O3/c1-50-39-8-3-2-7-37(39)47-27-24-45(25-28-47)21-5-4-6-31-9-18-38-40(30-31)51-42(49)48(38)29-26-46-22-19-34(20-23-46)41(32-10-14-35(43)15-11-32)33-12-16-36(44)17-13-33/h2-3,7-18,30H,4-6,19-29H2,1H3 IVSRQATZVDQHTP-UHFFFAOYSA-N 50290514 3-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-6-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-3H-benzooxazol-2-one::CHEMBL262167 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320657 104132066 CHEMBL262167 ZINC26575615 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484760 COc1ccccc1N1CCN(CCCCc2ccc3n(CCN4CCC(CC4)C(=O)c4ccc(F)cc4)c(=O)sc3c2)CC1 InChI=1S/C36H43FN4O3S/c1-44-33-8-3-2-7-31(33)40-23-20-38(21-24-40)17-5-4-6-27-9-14-32-34(26-27)45-36(43)41(32)25-22-39-18-15-29(16-19-39)35(42)28-10-12-30(37)13-11-28/h2-3,7-14,26,29H,4-6,15-25H2,1H3 QBKUPBPJZQRXGW-UHFFFAOYSA-N 50290511 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-6-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-3H-benzothiazol-2-one::CHEMBL314813 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290511&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9940262 104132063 CHEMBL314813 ZINC03917082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484764 Fc1ccc(cc1)C(=O)C1CCN(CCn2c3ccc(CCCCN4CCN(CC4)c4cccc(c4)C(F)(F)F)cc3sc2=O)CC1 InChI=1S/C36H40F4N4O2S/c37-30-10-8-27(9-11-30)34(45)28-13-16-42(17-14-28)20-23-44-32-12-7-26(24-33(32)47-35(44)46)4-1-2-15-41-18-21-43(22-19-41)31-6-3-5-29(25-31)36(38,39)40/h3,5-12,24-25,28H,1-2,4,13-23H2 QUYWOUGBIFGWJT-UHFFFAOYSA-N 50290507 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-6-{4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-3H-benzothiazol-2-one::CHEMBL87745 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290507&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19437818 104132059 CHEMBL87745 ZINC03916775 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50484770 Fc1ccc(cc1)C(=O)C1CCN(CCn2c3ccc(CCCCN4CCOCC4)cc3sc2=O)CC1 InChI=1S/C29H36FN3O3S/c30-25-7-5-23(6-8-25)28(34)24-10-13-32(14-11-24)15-16-33-26-9-4-22(21-27(26)37-29(33)35)3-1-2-12-31-17-19-36-20-18-31/h4-9,21,24H,1-3,10-20H2 NSPAPURIGJZYJN-UHFFFAOYSA-N 50290508 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-6-(4-morpholin-4-yl-butyl)-3H-benzothiazol-2-one::CHEMBL433345 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1016/S0960-894X(97)10023-3 10.7270/Q2QN66SR Diouf, O; Carato, P; Depreux, P; Bonte, JP; Caignard, DH; Guardiola-Lemaître, B; Rettori, MC; Belzung, C; Lesieur, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50290508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50290508&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15228924 104132060 CHEMBL433345 ZINC26574304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504388 COc1cc2CCN(C)[C@@H](Cc3ccc(Oc4cc(C[C@H]5N(C)CCc6cc(OC)c(O)cc56)ccc4OC)cc3)c2cc1O InChI=1S/C37H42N2O6/c1-38-14-12-25-19-35(43-4)32(40)21-28(25)30(38)16-23-6-9-27(10-7-23)45-37-18-24(8-11-34(37)42-3)17-31-29-22-33(41)36(44-5)20-26(29)13-15-39(31)2/h6-11,18-22,30-31,40-41H,12-17H2,1-5H3/t30-,31+/m0/s1 ZKGBUDJODLZAHS-IOWSJCHKSA-N 50292548 (+)-(1R,1'S)-thaligrisine hydrochloride::CHEMBL451734 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10031670 104134099 CHEMBL451734 ZINC44351713 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504389 COc1cc2CCN(C)[C@@H](Cc3ccc(Oc4cc(C[C@H]5N(C)CCc6cc(OC)c(O)cc56)ccc4O)cc3)c2cc1O InChI=1S/C36H40N2O6/c1-37-13-11-24-18-34(42-3)32(40)20-27(24)29(37)15-22-5-8-26(9-6-22)44-36-17-23(7-10-31(36)39)16-30-28-21-33(41)35(43-4)19-25(28)12-14-38(30)2/h5-10,17-21,29-30,39-41H,11-16H2,1-4H3/t29-,30+/m0/s1 FDABVSXGAMFQQH-XZWHSSHBSA-N 50292549 (+)-(1R,1'S)-berbamunine hydrochloride::CHEMBL503882 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 440585 104134100 16777 CHEMBL503882 C05177 ZINC04096650 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504390 COc1ccc(C[C@@H]2N(C)CCc3cc(OC)c(OC)cc23)cc1Oc1ccc(C[C@H]2N(C)CCc3cc(OC)c(OC)cc23)cc1 InChI=1S/C39H46N2O6/c1-40-16-14-27-21-35(43-4)37(45-6)23-30(27)32(40)18-25-8-11-29(12-9-25)47-39-20-26(10-13-34(39)42-3)19-33-31-24-38(46-7)36(44-5)22-28(31)15-17-41(33)2/h8-13,20-24,32-33H,14-19H2,1-7H3/t32-,33+/m1/s1 UHYCXSGUNAWVBW-SAIUNTKASA-N 50292466 CHEMBL450147::CHEMBL507970::Dimethylgrisabine D(2) dopamine receptor Rattus norvegicus 1450 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14137099 104134017 CHEMBL450147CHEMBL507970 ZINC05882795 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504391 COc1ccc(C[C@H]2N(C)CCc3cc(OC)c(OC)cc23)cc1Oc1ccc(C[C@H]2NCCc3cc(OC)c(OC)cc23)cc1 InChI=1S/C38H44N2O6/c1-40-16-14-27-21-35(43-4)37(45-6)23-30(27)32(40)18-25-9-12-33(41-2)38(19-25)46-28-10-7-24(8-11-28)17-31-29-22-36(44-5)34(42-3)20-26(29)13-15-39-31/h7-12,19-23,31-32,39H,13-18H2,1-6H3/t31-,32-/m1/s1 IUALMDJBFWMRDF-ROJLCIKYSA-N 50292471 CHEMBL449016::CHEMBL504801::Pampulhamine D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13992155 104134022 CHEMBL504801CHEMBL449016 ZINC42834669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504392 COc1ccc(C[C@H]2N(C)CCc3cc(OC)c(OC)cc23)cc1Oc1ccc(C[C@H]2N(C)CCc3cc(OC)c(OC)cc23)cc1 InChI=1S/C39H46N2O6/c1-40-16-14-27-21-35(43-4)37(45-6)23-30(27)32(40)18-25-8-11-29(12-9-25)47-39-20-26(10-13-34(39)42-3)19-33-31-24-38(46-7)36(44-5)22-28(31)15-17-41(33)2/h8-13,20-24,32-33H,14-19H2,1-7H3/t32-,33-/m1/s1 UHYCXSGUNAWVBW-CZNDPXEESA-N 50292469 CHEMBL443081::CHEMBL501861::O-methyldauricine D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292469&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 200521 104134020 CHEMBL443081CHEMBL501861 ZINC42805235 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504393 COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(Oc5c(O)c(OC)cc6CCN(C)[C@H](Cc7ccc(Oc1c2)cc7)c56)cc34 InChI=1S/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)17-23-8-11-30(41-3)32(18-23)44-26-9-6-22(7-10-26)16-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3/t28-,29+/m0/s1 YJRWQNIRFXVBRB-URLMMPGGSA-N 50292553 (R,S)-homoaromaline hydrochloride::CHEMBL443953 D(2) dopamine receptor Rattus norvegicus 66400 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292553&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9851833 104134104 CHEMBL443953 ZINC44306880 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504394 COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(OC)c(Oc5cc6[C@H](Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34 InChI=1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30+/m0/s1 WVTKBKWTSCPRNU-XZWHSSHBSA-N 85444 CHEMBL506025::Isotetrandrine (R,S)::Pheanthine (R,R) D(2) dopamine receptor Rattus norvegicus 670 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 457825 136351544 CHEMBL506025 C17060 ZINC38146181 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504395 COc1ccc2C[C@H]3N(C)CCc4cc(OC)c(Oc5c(OC)c(OC)cc6CCN(C)[C@@H](Cc7ccc(Oc1c2)cc7)c56)cc34 InChI=1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)18-24-9-12-31(41-3)33(19-24)45-27-10-7-23(8-11-27)17-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30+/m1/s1 FBCXFKWMGIWMJQ-IHLOFXLRSA-N 50241642 (+)-Obaberine::CHEMBL451211::CHEMBL464525::Obaberine D(2) dopamine receptor Rattus norvegicus 28400 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 100231 104098825 CHEMBL451211CHEMBL464525 C09596 ZINC30726940 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504396 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(c4)-c4cc(ccc4O)C(=O)[C@H]4N(C)CCc5cc(OC)c(Oc(c1O)c23)cc45 InChI=1S/C37H38N2O7/c1-38-12-11-22-18-32(45-5)36(42)37-33(22)27(38)15-20-6-9-29(43-3)26(14-20)25-16-23(7-8-28(25)40)35(41)34-24-19-31(46-37)30(44-4)17-21(24)10-13-39(34)2/h6-9,14,16-19,27,34,40,42H,10-13,15H2,1-5H3/t27-,34-/m0/s1 XCZPVAXCZZECDL-FOPBOCKXSA-N 50292556 (S,S)-oxandrine hydrochloride::CHEMBL445011 D(2) dopamine receptor Rattus norvegicus 2760 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44584684 104134107 CHEMBL445011 ZINC44305936 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504397 COc1cc2CCN(C)[C@H]3c2c(Oc2cc4[C@@H](Cc5ccc(OC)c(c5)-c5cc(ccc5O)C3=O)N(C)CCc4cc2OC)c1O InChI=1S/C37H38N2O7/c1-38-12-10-21-17-30(44-4)31-19-24(21)27(38)15-20-6-9-29(43-3)26(14-20)25-16-23(7-8-28(25)40)35(41)34-33-22(11-13-39(34)2)18-32(45-5)36(42)37(33)46-31/h6-9,14,16-19,27,34,40,42H,10-13,15H2,1-5H3/t27-,34+/m1/s1 RUAKOEPLVVXTGN-YJNPBZNESA-N 50292557 (S,R)-pseudoxandrine hydrochloride::CHEMBL504303 D(2) dopamine receptor Rattus norvegicus 16200 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44584686 104134108 CHEMBL504303 ZINC42808003 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504398 COc1cc2CCN(C)[C@H]3Cc4ccc(OC)c(c4)-c4cc(C[C@H]5N(C)CCc6cc(OC)c(Oc(c1O)c23)cc56)ccc4O InChI=1S/C37H40N2O6/c1-38-12-10-23-18-32(43-4)33-20-25(23)28(38)16-21-6-8-30(40)26(14-21)27-15-22(7-9-31(27)42-3)17-29-35-24(11-13-39(29)2)19-34(44-5)36(41)37(35)45-33/h6-9,14-15,18-20,28-29,40-41H,10-13,16-17H2,1-5H3/t28-,29+/m1/s1 MNNXIEANPHEHSB-WDYNHAJCSA-N 50292467 Antioquine::Antioquine (S,R)::CHEMBL446564::CHEMBL452904 D(2) dopamine receptor Rattus norvegicus 3180 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10393931 104134018 CHEMBL452904CHEMBL446564 ZINC42835355 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504399 COc1ccc(C=O)cc1Oc1ccc(C[C@@H]2N(C)CCc3cc(OC)c(OC)c(Oc4cc5C(=O)N(C)CCc5cc4OC)c23)cc1 InChI=1S/C38H40N2O8/c1-39-15-14-26-20-34(45-5)36(46-6)37(48-33-21-28-25(19-31(33)44-4)13-16-40(2)38(28)42)35(26)29(39)17-23-7-10-27(11-8-23)47-32-18-24(22-41)9-12-30(32)43-3/h7-12,18-22,29H,13-17H2,1-6H3/t29-/m0/s1 CCLPJGYXMUPSKC-LJAQVGFWSA-N 50292559 (S)-secoobaberine hydrochloride::CHEMBL451463 D(2) dopamine receptor Rattus norvegicus >30000 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10556238 104134110 CHEMBL451463 ZINC49833552 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504400 COc1cc2CCN(C)[C@@H](Cc3ccc(OC)c(c3)-c3cc(C=O)ccc3O)c2c(Oc2cc3C(=O)N(C)CCc3cc2OC)c1O InChI=1S/C37H38N2O8/c1-38-12-11-24-18-33(46-5)35(42)36(47-32-19-25-23(17-31(32)45-4)10-13-39(2)37(25)43)34(24)28(38)16-21-7-9-30(44-3)27(14-21)26-15-22(20-40)6-8-29(26)41/h6-9,14-15,17-20,28,41-42H,10-13,16H2,1-5H3/t28-/m0/s1 ZOBAYWQPWZMJPP-NDEPHWFRSA-N 50292473 CHEMBL450155::CHEMBL506299::Secantioquine D(2) dopamine receptor Rattus norvegicus 10000 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44559885 104134024 CHEMBL450155CHEMBL506299 ZINC49833487 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50504401 COc1ccc(C[C@@H]2N(C)CCc3cc(OC)c4Oc5cc6CCN(C)C(=O)c6cc5Oc4c23)cc1-c1cc(C=O)ccc1O InChI=1S/C36H34N2O7/c1-37-11-10-23-17-32(43-4)34-35(45-31-18-24-22(16-30(31)44-34)9-12-38(2)36(24)41)33(23)27(37)15-20-6-8-29(42-3)26(13-20)25-14-21(19-39)5-7-28(25)40/h5-8,13-14,16-19,27,40H,9-12,15H2,1-4H3/t27-/m0/s1 IPZZJEUUDCPILE-MHZLTWQESA-N 50292472 CHEMBL450834::CHEMBL509530::Secolucidine D(2) dopamine receptor Rattus norvegicus 81600 ChEMBL 10.1021/np50087a016 10.7270/Q2WM1DF2 1431946 Cortes, D; Figadere, B; Saez, J; Protais, P TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44559884 104134023 CHEMBL509530CHEMBL450834 ZINC42850828 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509884 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 311 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509885 CCCN(CCC)C1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3 MDBWEQVKJDMEMK-UHFFFAOYSA-N 50020221 (-)-5-hydroxy-2-(dipropylamino)tetralin::(-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::5-hydroxy-2-(dipropylamino)tetralin::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (DP-5-ADTN)::CHEMBL273273 D(2) dopamine receptor Rattus norvegicus 58.8 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 172267 103931135 CHEMBL273273 128 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509886 CCCN(CCN1CCN(CC1)c1ccccc1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C25H35N3O/c1-2-13-27(23-11-12-24-21(20-23)7-6-10-25(24)29)17-14-26-15-18-28(19-16-26)22-8-4-3-5-9-22/h3-10,23,29H,2,11-20H2,1H3/t23-/m0/s1 ACDYFMOSSUKHJD-QHCPKHFHSA-N 50273938 (-)-(S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::(S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::CHEMBL457024::D-237 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273938&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24754542 104117901 CHEMBL457024 ZINC28964118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509887 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccccc1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C28H37N5S/c1-2-14-32(25-12-13-26-27(21-25)34-28(29)30-26)18-15-31-16-19-33(20-17-31)24-10-8-23(9-11-24)22-6-4-3-5-7-22/h3-11,25H,2,12-21H2,1H3,(H2,29,30)/t25-/m0/s1 YDLWLYDTYNHXBM-VWLOTQADSA-N 50273996 (S)-N*6*-[2-(4-Biphenyl-4-yl-piperazin-1-yl)-ethyl]-N*6*-propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine::(S)-N6-(2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL514885::D-264 D(2) dopamine receptor Rattus norvegicus 264 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866612 104117939 CHEMBL514885 ZINC40379927 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509888 CCCN(CCN1CCN(CC1)c1ccccc1)[C@@H]1CCc2ccc(O)cc2C1 InChI=1S/C25H35N3O/c1-2-12-27(24-10-8-21-9-11-25(29)20-22(21)19-24)16-13-26-14-17-28(18-15-26)23-6-4-3-5-7-23/h3-7,9,11,20,24,29H,2,8,10,12-19H2,1H3/t24-/m1/s1 POVCSYONXDMZKL-XMMPIXPASA-N 50273937 (+)-(R)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::(R)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL456825::D-315 D(2) dopamine receptor Rattus norvegicus 40.6 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273937&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44588498 104117900 CHEMBL456825 ZINC22924455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509889 CCCN(CCN1CCN(CC1)C(=O)c1cc2ccccc2[nH]1)C1CCc2ccc(O)cc2C1 InChI=1S/C28H36N4O2/c1-2-11-31(24-9-7-21-8-10-25(33)19-23(21)18-24)15-12-30-13-16-32(17-14-30)28(34)27-20-22-5-3-4-6-26(22)29-27/h3-6,8,10,19-20,24,29,33H,2,7,9,11-18H2,1H3 WPHMPNDBLUZOLV-UHFFFAOYSA-N 50294838 (4-{2-[(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone::CHEMBL550089 D(2) dopamine receptor Rattus norvegicus 116 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294838&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45271437 104136369 CHEMBL550089 ZINC43010610 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509890 CCCN(CCN1CCN(Cc2cc3ccccc3[nH]2)CC1)C1CCc2ccc(O)cc2C1 InChI=1S/C28H38N4O/c1-2-11-32(26-9-7-22-8-10-27(33)20-24(22)19-26)17-16-30-12-14-31(15-13-30)21-25-18-23-5-3-4-6-28(23)29-25/h3-6,8,10,18,20,26,29,33H,2,7,9,11-17,19,21H2,1H3 RPRMJDRFAFJTHY-UHFFFAOYSA-N 50294839 7-({2-[4-(1H-Indol-2-ylmethyl)-piperazin-1-yl]-ethyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL549350 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269785 104136370 CHEMBL549350 ZINC43017401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509891 CCCN(CCN1CCN(Cc2ccc3[nH]ccc3c2)CC1)C1CCc2ccc(O)cc2C1 InChI=1S/C28H38N4O/c1-2-11-32(26-6-4-23-5-7-27(33)20-25(23)19-26)17-16-30-12-14-31(15-13-30)21-22-3-8-28-24(18-22)9-10-29-28/h3,5,7-10,18,20,26,29,33H,2,4,6,11-17,19,21H2,1H3 WSQNSMNIIQXLQN-UHFFFAOYSA-N 50294840 7-({2-[4-(1H-Indol-5-ylmethyl)-piperazin-1-yl]-ethyl}-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL551776 D(2) dopamine receptor Rattus norvegicus 144 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294840&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45272332 104136371 CHEMBL551776 ZINC43021792 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509892 CCCN(CCN1CCN(CC1)C(=O)c1ccc2[nH]ccc2c1)C1CCc2ccc(O)cc2C1 InChI=1S/C28H36N4O2/c1-2-11-31(25-6-3-21-4-7-26(33)20-24(21)19-25)15-12-30-13-16-32(17-14-30)28(34)23-5-8-27-22(18-23)9-10-29-27/h4-5,7-10,18,20,25,29,33H,2-3,6,11-17,19H2,1H3 KPYXPLTZRLPUAS-UHFFFAOYSA-N 50294841 (4-{2-[(7-hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-5-yl)-methanone::CHEMBL563131 D(2) dopamine receptor Rattus norvegicus 65.9 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294841&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45273206 104136372 CHEMBL563131 ZINC43120184 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509893 CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1)C1CCc2ccc(O)cc2C1 InChI=1S/C27H36N4O/c1-2-11-30(24-5-3-21-4-7-26(32)20-23(21)19-24)15-12-29-13-16-31(17-14-29)25-6-8-27-22(18-25)9-10-28-27/h4,6-10,18,20,24,28,32H,2-3,5,11-17,19H2,1H3 SSHCPHXGSFGAOS-UHFFFAOYSA-N 50294842 7-((2-(4-(1H-indol-5-yl)piperazin-1-yl)ethyl)(propyl)-amino)-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL551959 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294842&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45272335 104136373 CHEMBL551959 ZINC43120029 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509894 CCCN(CCN1CCN(CC1)C(=O)c1ccc2[nH]ccc2c1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C28H36N4O2/c1-2-12-31(24-7-8-25-21(20-24)4-3-5-27(25)33)16-13-30-14-17-32(18-15-30)28(34)23-6-9-26-22(19-23)10-11-29-26/h3-6,9-11,19,24,29,33H,2,7-8,12-18,20H2,1H3/t24-/m0/s1 HMYBAZWTOQSPCY-DEOSSOPVSA-N 50294843 (S)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-5-yl)-methanone::CHEMBL556269 D(2) dopamine receptor Rattus norvegicus 157 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45273211 104136374 CHEMBL556269 ZINC43021310 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509895 CCCN(CCN1CCN(CC1)C(=O)c1cc2ccccc2[nH]1)C1CCc2c(O)cccc2C1 InChI=1S/C28H36N4O2/c1-2-12-31(23-10-11-24-21(19-23)7-5-9-27(24)33)16-13-30-14-17-32(18-15-30)28(34)26-20-22-6-3-4-8-25(22)29-26/h3-9,20,23,29,33H,2,10-19H2,1H3 DQMMOHPPKACCQN-UHFFFAOYSA-N 50294844 (+)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone::(+/-)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone::(-)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone::CHEMBL551960 D(2) dopamine receptor Rattus norvegicus 51.2 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44188280 104136375 CHEMBL551960 ZINC43123396 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509896 CCCN(CCN1CCN(CC1)C(=O)c1cc2ccccc2[nH]1)C1CCc2c(O)cccc2C1 InChI=1S/C28H36N4O2/c1-2-12-31(23-10-11-24-21(19-23)7-5-9-27(24)33)16-13-30-14-17-32(18-15-30)28(34)26-20-22-6-3-4-8-25(22)29-26/h3-9,20,23,29,33H,2,10-19H2,1H3 DQMMOHPPKACCQN-UHFFFAOYSA-N 50294844 (+)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone::(+/-)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone::(-)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone::CHEMBL551960 D(2) dopamine receptor Rattus norvegicus 47.5 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44188280 104136375 CHEMBL551960 ZINC43123396 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509897 CCCN(CCN1CCN(CC1)C(=O)c1cc2ccccc2[nH]1)C1CCc2c(O)cccc2C1 InChI=1S/C28H36N4O2/c1-2-12-31(23-10-11-24-21(19-23)7-5-9-27(24)33)16-13-30-14-17-32(18-15-30)28(34)26-20-22-6-3-4-8-25(22)29-26/h3-9,20,23,29,33H,2,10-19H2,1H3 DQMMOHPPKACCQN-UHFFFAOYSA-N 50294844 (+)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone::(+/-)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone::(-)-(4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-2-yl)-methanone::CHEMBL551960 D(2) dopamine receptor Rattus norvegicus 47.5 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44188280 104136375 CHEMBL551960 ZINC43123396 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509898 CCCN(CCN1CCN(CC1)C(=O)c1c[nH]c2ccccc12)C1CCc2c(O)cccc2C1 InChI=1S/C28H36N4O2/c1-2-12-31(22-10-11-23-21(19-22)6-5-9-27(23)33)16-13-30-14-17-32(18-15-30)28(34)25-20-29-26-8-4-3-7-24(25)26/h3-9,20,22,29,33H,2,10-19H2,1H3 RMHOFEFHGRLHFR-UHFFFAOYSA-N 50294845 (4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indol-3-yl)-methanone::CHEMBL556685 D(2) dopamine receptor Rattus norvegicus 58.9 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45273217 104136376 CHEMBL556685 ZINC43060010 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509899 CCCN(CCN1CCN(CC1)C(=O)c1n[nH]c2ccccc12)C1CCc2c(O)cccc2C1 InChI=1S/C27H35N5O2/c1-2-12-31(21-10-11-22-20(19-21)6-5-9-25(22)33)16-13-30-14-17-32(18-15-30)27(34)26-23-7-3-4-8-24(23)28-29-26/h3-9,21,33H,2,10-19H2,1H3,(H,28,29) FWNRTOASMIUOIB-UHFFFAOYSA-N 50294846 (4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-(1H-indazol-3-yl)-methanone::CHEMBL561307 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294846&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45268064 104136377 CHEMBL561307 ZINC43122596 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509900 CCCN(CCN1CCN(CC1)C(=O)c1cc2ccccc2o1)C1CCc2c(O)cccc2C1 InChI=1S/C28H35N3O3/c1-2-12-30(23-10-11-24-21(19-23)7-5-8-25(24)32)16-13-29-14-17-31(18-15-29)28(33)27-20-22-6-3-4-9-26(22)34-27/h3-9,20,23,32H,2,10-19H2,1H3 BEZQDVRSAHYQKR-UHFFFAOYSA-N 50294847 Benzofuran-2-yl-(4-{2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-methanone::CHEMBL549968 D(2) dopamine receptor Rattus norvegicus 132 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269797 104136378 CHEMBL549968 ZINC43011939 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509901 CCCN(CCN1CCN(CC1)C(=O)c1cc2ccccc2s1)C1CCc2c(O)cccc2C1 InChI=1S/C28H35N3O2S/c1-2-12-30(23-10-11-24-21(19-23)7-5-8-25(24)32)16-13-29-14-17-31(18-15-29)28(33)27-20-22-6-3-4-9-26(22)34-27/h3-9,20,23,32H,2,10-19H2,1H3 VPRUUPSNGKFQJD-UHFFFAOYSA-N 50294848 Benzo[b]thiophen-2-yl-(4-{2-[(5-hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-methanone::CHEMBL559459 D(2) dopamine receptor Rattus norvegicus 76.9 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45267206 104136379 CHEMBL559459 ZINC43073990 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50509902 CCCN(CCN1CCN(CC1)C(=O)c1cnc2ccccc2c1)C1CCc2c(O)cccc2C1 InChI=1S/C29H36N4O2/c1-2-12-32(25-10-11-26-22(20-25)7-5-9-28(26)34)16-13-31-14-17-33(18-15-31)29(35)24-19-23-6-3-4-8-27(23)30-21-24/h3-9,19,21,25,34H,2,10-18,20H2,1H3 CORRNILCUDTMSS-UHFFFAOYSA-N 50294849 (4-{2-[(5-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-ethyl}-piperazin-1-yl)-quinolin-3-ylmethanone::CHEMBL561511 D(2) dopamine receptor Rattus norvegicus 158 ChEMBL 10.1016/j.bmc.2009.04.031 10.7270/Q25H7G8C 19427222 Brown, DA; Mishra, M; Zhang, S; Biswas, S; Parrington, I; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294849&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45268070 104136380 CHEMBL561511 ZINC43069216 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512279 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 197 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512280 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 11.5 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512281 CN1CCc2cc(C)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C18H19NO2/c1-10-7-12-5-6-19(2)14-9-11-3-4-15(20)18(21)17(11)13(8-10)16(12)14/h3-4,7-8,14,20-21H,5-6,9H2,1-2H3/t14-/m1/s1 QRJZCXSRTBCYIW-CQSZACIVSA-N 50251028 (R)-(-)-2-Methyl-apomorphine hydrochloride::CHEMBL507567::CHEMBL557547 D(2) dopamine receptor Rattus norvegicus 20.7 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567292 104104362 CHEMBL557547CHEMBL507567 ZINC40846701 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512282 CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1 InChI=1S/C23H21NO2/c1-24-10-9-16-11-17(14-5-3-2-4-6-14)12-18-21(16)19(24)13-15-7-8-20(25)23(26)22(15)18/h2-8,11-12,19,25-26H,9-10,13H2,1H3/t19-/m1/s1 NJWHLJABYCIZPL-LJQANCHMSA-N 50251026 (R)-(-)-2-Phenyl-apomorphine hydrochloride::CHEMBL458397::CHEMBL465054 D(2) dopamine receptor Rattus norvegicus 11.7 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11515697 104104360 CHEMBL458397CHEMBL465054 ZINC40863607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512283 CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccc(O)cc1 InChI=1S/C23H21NO3/c1-24-9-8-15-10-16(13-2-5-17(25)6-3-13)11-18-21(15)19(24)12-14-4-7-20(26)23(27)22(14)18/h2-7,10-11,19,25-27H,8-9,12H2,1H3/t19-/m1/s1 IEYKUJATGFZIHM-LJQANCHMSA-N 50251027 (R)-(-)-2-(4-Hydroxyphenyl)-apomorphine hydrochloride::CHEMBL458579::CHEMBL517028 D(2) dopamine receptor Rattus norvegicus 4.14 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11639064 104104361 CHEMBL517028CHEMBL458579 ZINC35982742 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512284 CCN1CCc2cc(C)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-3-20-7-6-13-8-11(2)9-14-17(13)15(20)10-12-4-5-16(21)19(22)18(12)14/h4-5,8-9,15,21-22H,3,6-7,10H2,1-2H3/t15-/m1/s1 VNGYREUWVHTKAV-OAHLLOKOSA-N 50295861 CHEMBL562460::N-Ethyl-2-methylnorapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 115 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45267373 104137392 CHEMBL562460 ZINC43123260 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512285 CCN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1 InChI=1S/C24H23NO2/c1-2-25-11-10-17-12-18(15-6-4-3-5-7-15)13-19-22(17)20(25)14-16-8-9-21(26)24(27)23(16)19/h3-9,12-13,20,26-27H,2,10-11,14H2,1H3/t20-/m1/s1 RJCYHSVPFFEYKA-HXUWFJFHSA-N 50295862 CHEMBL564909::N-Ethyl-2-phenylnorapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45271622 104137393 CHEMBL564909 ZINC43061376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512286 CCN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccc(O)cc1 InChI=1S/C24H23NO3/c1-2-25-10-9-16-11-17(14-3-6-18(26)7-4-14)12-19-22(16)20(25)13-15-5-8-21(27)24(28)23(15)19/h3-8,11-12,20,26-28H,2,9-10,13H2,1H3/t20-/m1/s1 LXMBBFMKKSPIBR-HXUWFJFHSA-N 50295863 CHEMBL562935::N-Ethyl-2-(4-hydroxyphenyl)-norapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 1.5 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44241581 104137394 CHEMBL562935 ZINC42989613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512287 CCCN1CCc2cc(C)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H23NO2/c1-3-7-21-8-6-14-9-12(2)10-15-18(14)16(21)11-13-4-5-17(22)20(23)19(13)15/h4-5,9-10,16,22-23H,3,6-8,11H2,1-2H3/t16-/m1/s1 IQXHLUBOFQZZLM-MRXNPFEDSA-N 50295864 CHEMBL550180::N-Propyl-2-methylnorapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 9.2 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269964 104137395 CHEMBL550180 ZINC43014509 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512288 CCCN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1 InChI=1S/C25H25NO2/c1-2-11-26-12-10-18-13-19(16-6-4-3-5-7-16)14-20-23(18)21(26)15-17-8-9-22(27)25(28)24(17)20/h3-9,13-14,21,27-28H,2,10-12,15H2,1H3/t21-/m1/s1 DSINXCRDVCZBKB-OAQYLSRUSA-N 50295865 CHEMBL550792::N-Propyl-2-phenylnorapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 192 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295865&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269974 104137396 CHEMBL550792 ZINC43013693 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512289 CCCN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccc(O)cc1 InChI=1S/C25H25NO3/c1-2-10-26-11-9-17-12-18(15-3-6-19(27)7-4-15)13-20-23(17)21(26)14-16-5-8-22(28)25(29)24(16)20/h3-8,12-13,21,27-29H,2,9-11,14H2,1H3/t21-/m1/s1 UIDHCUWLPJKWMW-OAQYLSRUSA-N 50295866 CHEMBL560721::N-Propyl-2-(4-hydroxyphenyl)-norapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44241577 104137397 CHEMBL560721 ZINC43120417 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512290 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 1425 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512291 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512292 CN1CCc2cc(C)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C18H19NO2/c1-10-7-12-5-6-19(2)14-9-11-3-4-15(20)18(21)17(11)13(8-10)16(12)14/h3-4,7-8,14,20-21H,5-6,9H2,1-2H3/t14-/m1/s1 QRJZCXSRTBCYIW-CQSZACIVSA-N 50251028 (R)-(-)-2-Methyl-apomorphine hydrochloride::CHEMBL507567::CHEMBL557547 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44567292 104104362 CHEMBL557547CHEMBL507567 ZINC40846701 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512293 CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1 InChI=1S/C23H21NO2/c1-24-10-9-16-11-17(14-5-3-2-4-6-14)12-18-21(16)19(24)13-15-7-8-20(25)23(26)22(15)18/h2-8,11-12,19,25-26H,9-10,13H2,1H3/t19-/m1/s1 NJWHLJABYCIZPL-LJQANCHMSA-N 50251026 (R)-(-)-2-Phenyl-apomorphine hydrochloride::CHEMBL458397::CHEMBL465054 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251026&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11515697 104104360 CHEMBL458397CHEMBL465054 ZINC40863607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512294 CN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccc(O)cc1 InChI=1S/C23H21NO3/c1-24-9-8-15-10-16(13-2-5-17(25)6-3-13)11-18-21(15)19(24)12-14-4-7-20(26)23(27)22(14)18/h2-7,10-11,19,25-27H,8-9,12H2,1H3/t19-/m1/s1 IEYKUJATGFZIHM-LJQANCHMSA-N 50251027 (R)-(-)-2-(4-Hydroxyphenyl)-apomorphine hydrochloride::CHEMBL458579::CHEMBL517028 D(2) dopamine receptor Rattus norvegicus 8.5 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251027&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11639064 104104361 CHEMBL517028CHEMBL458579 ZINC35982742 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512295 CCN1CCc2cc(C)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-3-20-7-6-13-8-11(2)9-14-17(13)15(20)10-12-4-5-16(21)19(22)18(12)14/h4-5,8-9,15,21-22H,3,6-7,10H2,1-2H3/t15-/m1/s1 VNGYREUWVHTKAV-OAHLLOKOSA-N 50295861 CHEMBL562460::N-Ethyl-2-methylnorapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 480 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45267373 104137392 CHEMBL562460 ZINC43123260 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512296 CCN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1 InChI=1S/C24H23NO2/c1-2-25-11-10-17-12-18(15-6-4-3-5-7-15)13-19-22(17)20(25)14-16-8-9-21(26)24(27)23(16)19/h3-9,12-13,20,26-27H,2,10-11,14H2,1H3/t20-/m1/s1 RJCYHSVPFFEYKA-HXUWFJFHSA-N 50295862 CHEMBL564909::N-Ethyl-2-phenylnorapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45271622 104137393 CHEMBL564909 ZINC43061376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512297 CCN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccc(O)cc1 InChI=1S/C24H23NO3/c1-2-25-10-9-16-11-17(14-3-6-18(26)7-4-14)12-19-22(16)20(25)13-15-5-8-21(27)24(28)23(15)19/h3-8,11-12,20,26-28H,2,9-10,13H2,1H3/t20-/m1/s1 LXMBBFMKKSPIBR-HXUWFJFHSA-N 50295863 CHEMBL562935::N-Ethyl-2-(4-hydroxyphenyl)-norapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 8.7 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44241581 104137394 CHEMBL562935 ZINC42989613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512298 CCCN1CCc2cc(C)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H23NO2/c1-3-7-21-8-6-14-9-12(2)10-15-18(14)16(21)11-13-4-5-17(22)20(23)19(13)15/h4-5,9-10,16,22-23H,3,6-8,11H2,1-2H3/t16-/m1/s1 IQXHLUBOFQZZLM-MRXNPFEDSA-N 50295864 CHEMBL550180::N-Propyl-2-methylnorapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269964 104137395 CHEMBL550180 ZINC43014509 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512299 CCCN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccccc1 InChI=1S/C25H25NO2/c1-2-11-26-12-10-18-13-19(16-6-4-3-5-7-16)14-20-23(18)21(26)15-17-8-9-22(27)25(28)24(17)20/h3-9,13-14,21,27-28H,2,10-12,15H2,1H3/t21-/m1/s1 DSINXCRDVCZBKB-OAQYLSRUSA-N 50295865 CHEMBL550792::N-Propyl-2-phenylnorapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 577 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295865&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45269974 104137396 CHEMBL550792 ZINC43013693 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50512300 CCCN1CCc2cc(cc-3c2[C@H]1Cc1ccc(O)c(O)c-31)-c1ccc(O)cc1 InChI=1S/C25H25NO3/c1-2-10-26-11-9-17-12-18(15-3-6-19(27)7-4-15)13-20-23(17)21(26)14-16-5-8-22(28)25(29)24(16)20/h3-8,12-13,21,27-29H,2,9-11,14H2,1H3/t21-/m1/s1 UIDHCUWLPJKWMW-OAQYLSRUSA-N 50295866 CHEMBL560721::N-Propyl-2-(4-hydroxyphenyl)-norapomorphine hydrochloride D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/j.bmc.2009.04.047 10.7270/Q2KD1XZ4 19454369 Herm, L; Berenyi, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44241577 104137397 CHEMBL560721 ZINC43120417 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50537923 Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c23)n1CCCN1CCN(CC1)c1ccccc1 InChI=1S/C23H29N7O2/c1-17-16-30-19-20(25(2)23(32)26(3)21(19)31)24-22(30)29(17)11-7-10-27-12-14-28(15-13-27)18-8-5-4-6-9-18/h4-6,8-9,16H,7,10-15H2,1-3H3 GQBKCNRAKIZTLJ-UHFFFAOYSA-N 50301627 7-Methyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-1,3-dimethyl-(1H,8H)-imidazo[2,1-f]purine-2,4-dione::CHEMBL585300 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.ejmech.2009.07.014 10.7270/Q2C53KWK 19679379 Zagorska, A; Jurczyk, S; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301627&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16812281 104155988 CHEMBL585300 ZINC09421115 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50537926 COc1ccccc1N1CCN(CCCn2c(C)cn3c2nc2n(C)c(=O)n(C)c(=O)c32)CC1 InChI=1S/C24H31N7O3/c1-17-16-31-20-21(26(2)24(33)27(3)22(20)32)25-23(31)30(17)11-7-10-28-12-14-29(15-13-28)18-8-5-6-9-19(18)34-4/h5-6,8-9,16H,7,10-15H2,1-4H3 BIQBLMZWRXRLPF-UHFFFAOYSA-N 50301628 7-Methyl-8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-yl-propyl]-1,3-dimethyl-(1H,8H)-imidazo[2,1-f]purine-2,4-dione::CHEMBL585503 D(2) dopamine receptor Rattus norvegicus 344.7 ChEMBL 10.1016/j.ejmech.2009.07.014 10.7270/Q2C53KWK 19679379 Zagorska, A; Jurczyk, S; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301628&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44512625 104155989 CHEMBL585503 ZINC45322183 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50537929 Cn1c2nc3n(CCCN4CCN(CC4)c4ccccc4)ccn3c2c(=O)n(C)c1=O InChI=1S/C22H27N7O2/c1-24-19-18(20(30)25(2)22(24)31)29-16-15-28(21(29)23-19)10-6-9-26-11-13-27(14-12-26)17-7-4-3-5-8-17/h3-5,7-8,15-16H,6,9-14H2,1-2H3 AOAWROOBGZLWJS-UHFFFAOYSA-N 50301629 8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-1,3-dimethyl-(1H,8H)-imidazo[2,1-f]purine-2,4-dione::CHEMBL585105 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.ejmech.2009.07.014 10.7270/Q2C53KWK 19679379 Zagorska, A; Jurczyk, S; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301629&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44517350 104155990 CHEMBL585105 ZINC45320086 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50537932 COc1ccccc1N1CCN(CCCn2ccn3c2nc2n(C)c(=O)n(C)c(=O)c32)CC1 InChI=1S/C23H29N7O3/c1-25-20-19(21(31)26(2)23(25)32)30-16-15-29(22(30)24-20)10-6-9-27-11-13-28(14-12-27)17-7-4-5-8-18(17)33-3/h4-5,7-8,15-16H,6,9-14H2,1-3H3 RJWDXQQJQDKNAH-UHFFFAOYSA-N 50301630 8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-yl-propyl]-1,3-dimethyl-(1H,8H)-imidazo[2,1-f]purine-2,4-dione::CHEMBL565423 D(2) dopamine receptor Rattus norvegicus 839 ChEMBL 10.1016/j.ejmech.2009.07.014 10.7270/Q2C53KWK 19679379 Zagorska, A; Jurczyk, S; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301630&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44517352 104155991 CHEMBL565423 ZINC45253428 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50537935 Cn1c2nc3n(CCCN4CCN(CC4)c4cccc(Cl)c4)ccn3c2c(=O)n(C)c1=O InChI=1S/C22H26ClN7O2/c1-25-19-18(20(31)26(2)22(25)32)30-14-13-29(21(30)24-19)8-4-7-27-9-11-28(12-10-27)17-6-3-5-16(23)15-17/h3,5-6,13-15H,4,7-12H2,1-2H3 AEQRKKLCVSMSAY-UHFFFAOYSA-N 50301631 8-[3-(N4-3'-chlorophenyl)-piperazin-N1-yl-propyl]-1,3-dimethyl-(1H,8H)-imidazo[2,1-f]purine-2,4-dione::CHEMBL566890 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.ejmech.2009.07.014 10.7270/Q2C53KWK 19679379 Zagorska, A; Jurczyk, S; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301631&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44512622 104155992 CHEMBL566890 ZINC45244903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50537940 Cc1cn2c(nc3n(C)c(=O)n(C)c(=O)c23)n1CCCN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C23H28ClN7O2/c1-16-15-31-19-20(26(2)23(33)27(3)21(19)32)25-22(31)30(16)9-5-8-28-10-12-29(13-11-28)18-7-4-6-17(24)14-18/h4,6-7,14-15H,5,8-13H2,1-3H3 NSAFBDJYALKWHC-UHFFFAOYSA-N 50301632 7-Methyl-8-[3-(N4-3'-chlorophenyl)-piperazin-N1-yl-propyl]-1,3-dimethyl-(1H,8H)-imidazo[2,1-f]purine-2,4-dione::CHEMBL567496 D(2) dopamine receptor Rattus norvegicus 767.2 ChEMBL 10.1016/j.ejmech.2009.07.014 10.7270/Q2C53KWK 19679379 Zagorska, A; Jurczyk, S; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301632&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17599548 104155993 CHEMBL567496 ZINC10049531 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50537943 Cn1c2nc3n(CCCN4CCN(CC4)c4ccccc4)c(cn3c2c(=O)n(C)c1=O)-c1ccccc1 InChI=1S/C28H31N7O2/c1-30-25-24(26(36)31(2)28(30)37)35-20-23(21-10-5-3-6-11-21)34(27(35)29-25)15-9-14-32-16-18-33(19-17-32)22-12-7-4-8-13-22/h3-8,10-13,20H,9,14-19H2,1-2H3 GANDOFQJHIQVLA-UHFFFAOYSA-N 50301633 7-Phenyl-8-[3-(N4-phenyl)-piperazin-N1-yl-propyl]-1,3-dimethyl-(1H,8H)-imidazo[2,1-f]purine-2,4-dione::CHEMBL566235 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.ejmech.2009.07.014 10.7270/Q2C53KWK 19679379 Zagorska, A; Jurczyk, S; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301633&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44512956 104155994 CHEMBL566235 ZINC45253989 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50537946 COc1ccccc1N1CCN(CCCn2c(cn3c2nc2n(C)c(=O)n(C)c(=O)c32)-c2ccccc2)CC1 InChI=1S/C29H33N7O3/c1-31-26-25(27(37)32(2)29(31)38)36-20-23(21-10-5-4-6-11-21)35(28(36)30-26)15-9-14-33-16-18-34(19-17-33)22-12-7-8-13-24(22)39-3/h4-8,10-13,20H,9,14-19H2,1-3H3 IFNDRFYBHSYWBF-UHFFFAOYSA-N 50301634 7-Phenyl-8-[3-(N4-2'-methoxyphenyl)-piperazin-N1-yl-propyl]-1,3-dimethyl-(1H,8H)-imidazo[2,1-f]purine-2,4-dione::CHEMBL565405 D(2) dopamine receptor Rattus norvegicus 143 ChEMBL 10.1016/j.ejmech.2009.07.014 10.7270/Q2C53KWK 19679379 Zagorska, A; Jurczyk, S; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301634&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44513277 104155995 CHEMBL565405 ZINC45245645 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50537955 Cn1c2nc3nc(NCCCN4CCN(CC4)c4ccccc4)c(Br)cn3c2c(=O)n(C)c1=O InChI=1S/C23H27BrN8O2/c1-28-20-18(21(33)29(2)23(28)34)32-15-17(24)19(26-22(32)27-20)25-9-6-10-30-11-13-31(14-12-30)16-7-4-3-5-8-16/h3-5,7-8,15H,6,9-14H2,1-2H3,(H,25,26,27) ODQOBVAPJLPYJD-UHFFFAOYSA-N 50301639 6-Bromo-1,3-dimethyl-7-[3-(4-phenyl-piperazin-1-yl)-propylamino]-1H-1,3,4b,8,9-pentaaza-fluorene-2,4-dione::7-bromo-1,3-dimethyl-8-(3-(4-phenylpiperazin-1-yl)propylamino)pyrimido[1,2-f]purine-2,4(1H,3H)-dione::CHEMBL195047 D(2) dopamine receptor Rattus norvegicus 414 ChEMBL 10.1016/j.ejmech.2009.07.014 10.7270/Q2C53KWK 19679379 Zagorska, A; Jurczyk, S; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Nikiforuk, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301639&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11180043 104156000 CHEMBL195047 ZINC03838264 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50531103 CCCCC1NCCc2cc(Cl)c(O)cc12 InChI=1S/C13H18ClNO/c1-2-3-4-12-10-8-13(16)11(14)7-9(10)5-6-15-12/h7-8,12,15-16H,2-6H2,1H3 ACJUSWFGYPTYCW-UHFFFAOYSA-N 50298706 1-Butyl-6-chloro-7-hydroxy-1,2,3,4-tetrahydroisoquinoline::CHEMBL574111 D(2) dopamine receptor Rattus norvegicus 76 ChEMBL 10.1016/j.bmc.2009.05.079 10.7270/Q26D5T2B 19540762 Berenguer, I; El Aouad, N; Andujar, S; Romero, V; Suvire, F; Freret, T; Bermejo, A; Ivorra, MD; Enriz, RD; Boulouard, M; Cabedo, N; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298706&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45481841 104140235 CHEMBL574111 ZINC45284820 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50531104 Oc1cc2C(Cc3ccccc3)NCCc2cc1Cl InChI=1S/C16H16ClNO/c17-14-9-12-6-7-18-15(13(12)10-16(14)19)8-11-4-2-1-3-5-11/h1-5,9-10,15,18-19H,6-8H2 SQICKVBXLWYACA-UHFFFAOYSA-N 50298707 1-Benzyl-6-chloro-7-hydroxy-1,2,3,4-tetrahydroisoquinoline::CHEMBL574695 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1016/j.bmc.2009.05.079 10.7270/Q26D5T2B 19540762 Berenguer, I; El Aouad, N; Andujar, S; Romero, V; Suvire, F; Freret, T; Bermejo, A; Ivorra, MD; Enriz, RD; Boulouard, M; Cabedo, N; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50298707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50298707&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45481864 104140236 CHEMBL574695 ZINC45288334 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50531105 CN1CCc2cc(Cl)c(O)cc2C1c1ccccc1 InChI=1S/C16H16ClNO/c1-18-8-7-12-9-14(17)15(19)10-13(12)16(18)11-5-3-2-4-6-11/h2-6,9-10,16,19H,7-8H2,1H3 AVXGCGYACIYZAR-UHFFFAOYSA-N 50022051 1-Phenyl-6-chloro-7-hydroxy-N-methyl-1,2,3,4-tetrahydroisoquinoline::6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::CHEMBL57579 D(2) dopamine receptor Rattus norvegicus 504 ChEMBL 10.1016/j.bmc.2009.05.079 10.7270/Q26D5T2B 19540762 Berenguer, I; El Aouad, N; Andujar, S; Romero, V; Suvire, F; Freret, T; Bermejo, A; Ivorra, MD; Enriz, RD; Boulouard, M; Cabedo, N; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198584 103932732 CHEMBL57579 ZINC13675796 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572200 CC1(NC(=O)N(CCCN2CCN(CC2)c2cccc(Cl)c2)C1=O)c1ccccc1 InChI=1S/C23H27ClN4O2/c1-23(18-7-3-2-4-8-18)21(29)28(22(30)25-23)12-6-11-26-13-15-27(16-14-26)20-10-5-9-19(24)17-20/h2-5,7-10,17H,6,11-16H2,1H3,(H,25,30) KYCKSTNLWKOHQH-UHFFFAOYSA-N 50316326 CHEMBL1098614::rac-5-Methyl-5-pheny-3-{3-[4-(3-chlorophenyl)piperazin-1-yl]-propyl}-imidazolidine-2,4-dione D(2) dopamine receptor Rattus norvegicus 3900 ChEMBL 10.1016/j.ejmech.2009.11.053 10.7270/Q2WM1DKV 20060623 Czopek, A; Byrtus, H; Kolaczkowski, M; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Wesolowska, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46191860 104150687 CHEMBL1098614 ZINC49116148 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572201 O=C1NC2(CCc3ccccc23)C(=O)N1CCCN1CCN(CC1)c1ccccc1 InChI=1S/C24H28N4O2/c29-22-24(12-11-19-7-4-5-10-21(19)24)25-23(30)28(22)14-6-13-26-15-17-27(18-16-26)20-8-2-1-3-9-20/h1-5,7-10H,6,11-18H2,(H,25,30) UMLQEUFOJFONRU-UHFFFAOYSA-N 50316327 CHEMBL1096275::rac-1-[3-(4-Phenylpiperazin-1-yl)propyl]-2',3'-dihydrospiro[imidazolidine-4,1'-indene]-2,5-dione D(2) dopamine receptor Rattus norvegicus 15600 ChEMBL 10.1016/j.ejmech.2009.11.053 10.7270/Q2WM1DKV 20060623 Czopek, A; Byrtus, H; Kolaczkowski, M; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Wesolowska, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46191868 104150688 CHEMBL1096275 ZINC49089053 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50573867 COc1ccccc1N1CCN(CCCN=C(NC#N)c2ccncc2)CC1 InChI=1S/C21H26N6O/c1-28-20-6-3-2-5-19(20)27-15-13-26(14-16-27)12-4-9-24-21(25-17-22)18-7-10-23-11-8-18/h2-3,5-8,10-11H,4,9,12-16H2,1H3,(H,24,25) PCSRINCTRTWFDX-UHFFFAOYSA-N 50316960 CHEMBL1099374::N'-cyano-N-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)isonicotinamidine D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2010.02.106 10.7270/Q2QR4X80 20347301 Fiorino, F; Severino, B; De Angelis, F; Perissutti, E; Magli, E; Frecentese, F; Esposito, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46861870 104151321 CHEMBL1099374 ZINC49048122 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50573868 CCOc1ccccc1N1CCN(CCCN=C(NC#N)c2ccncc2)CC1 InChI=1S/C22H28N6O/c1-2-29-21-7-4-3-6-20(21)28-16-14-27(15-17-28)13-5-10-25-22(26-18-23)19-8-11-24-12-9-19/h3-4,6-9,11-12H,2,5,10,13-17H2,1H3,(H,25,26) VOWPZTJZZPVECG-UHFFFAOYSA-N 50316970 CHEMBL1087182::N'-cyano-N-(3-(4-(2-ethoxyphenyl)piperazin-1-yl)propyl)isonicotinamidine D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2010.02.106 10.7270/Q2QR4X80 20347301 Fiorino, F; Severino, B; De Angelis, F; Perissutti, E; Magli, E; Frecentese, F; Esposito, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316970&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46861871 104151331 CHEMBL1087182 ZINC49052353 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50573869 Clc1cccc(c1)N1CCN(CCCN=C(NC#N)c2ccncc2)CC1 InChI=1S/C20H23ClN6/c21-18-3-1-4-19(15-18)27-13-11-26(12-14-27)10-2-7-24-20(25-16-22)17-5-8-23-9-6-17/h1,3-6,8-9,15H,2,7,10-14H2,(H,24,25) UYPUJSDZUUVYIA-UHFFFAOYSA-N 50316967 CHEMBL1086958::N-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-N'-cyanoisonicotinamidine D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2010.02.106 10.7270/Q2QR4X80 20347301 Fiorino, F; Severino, B; De Angelis, F; Perissutti, E; Magli, E; Frecentese, F; Esposito, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46889212 104151328 CHEMBL1086958 ZINC49050787 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50573870 N#CNC(=NCCCN1CCN(CC1)c1ccccn1)c1ccncc1 InChI=1S/C19H23N7/c20-16-24-19(17-5-9-21-10-6-17)23-8-3-11-25-12-14-26(15-13-25)18-4-1-2-7-22-18/h1-2,4-7,9-10H,3,8,11-15H2,(H,23,24) JPCJGSJYXPPMAF-UHFFFAOYSA-N 50316964 CHEMBL1086961::N'-cyano-N-(3-(4-(pyridin-2-yl)piperazin-1-yl)propyl)isonicotinamidine D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmcl.2010.02.106 10.7270/Q2QR4X80 20347301 Fiorino, F; Severino, B; De Angelis, F; Perissutti, E; Magli, E; Frecentese, F; Esposito, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46861872 104151325 CHEMBL1086961 ZINC49112112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572202 Clc1cccc(c1)N1CCN(CCCN2C(=O)NC3(CCc4ccccc34)C2=O)CC1 InChI=1S/C24H27ClN4O2/c25-19-6-3-7-20(17-19)28-15-13-27(14-16-28)11-4-12-29-22(30)24(26-23(29)31)10-9-18-5-1-2-8-21(18)24/h1-3,5-8,17H,4,9-16H2,(H,26,31) IARDVIOHDKSEPI-UHFFFAOYSA-N 50316322 CHEMBL1098609::rac-1-{3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl}-2',3'-dihydrospiro[imidazolidine-4,1'-indene]-2,5-dione D(2) dopamine receptor Rattus norvegicus 6200 ChEMBL 10.1016/j.ejmech.2009.11.053 10.7270/Q2WM1DKV 20060623 Czopek, A; Byrtus, H; Kolaczkowski, M; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Wesolowska, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316322&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46192015 104150683 CHEMBL1098609 ZINC49089020 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572203 O=C1NC2(CCCc3ccccc23)C(=O)N1CCCN1CCN(CC1)c1ccccc1 InChI=1S/C25H30N4O2/c30-23-25(13-6-9-20-8-4-5-12-22(20)25)26-24(31)29(23)15-7-14-27-16-18-28(19-17-27)21-10-2-1-3-11-21/h1-5,8,10-12H,6-7,9,13-19H2,(H,26,31) XATUHDUVAWBHDD-UHFFFAOYSA-N 50316323 CHEMBL1098286::rac-1-[3-(4-Phenylpiperazin-1-yl)propyl]-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione D(2) dopamine receptor Rattus norvegicus 675 ChEMBL 10.1016/j.ejmech.2009.11.053 10.7270/Q2WM1DKV 20060623 Czopek, A; Byrtus, H; Kolaczkowski, M; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Wesolowska, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46192017 104150684 CHEMBL1098286 ZINC49088462 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572204 COc1ccccc1N1CCN(CCCN2C(=O)NC3(CCCc4ccccc34)C2=O)CC1 InChI=1S/C26H32N4O3/c1-33-23-12-5-4-11-22(23)29-18-16-28(17-19-29)14-7-15-30-24(31)26(27-25(30)32)13-6-9-20-8-2-3-10-21(20)26/h2-5,8,10-12H,6-7,9,13-19H2,1H3,(H,27,32) OUXGCTLOLJELQS-UHFFFAOYSA-N 50316324 CHEMBL1098287::rac-1-{3-[4-(2-Methoxyphenyl)piperazin-1-yl]propyl}-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione D(2) dopamine receptor Rattus norvegicus 965 ChEMBL 10.1016/j.ejmech.2009.11.053 10.7270/Q2WM1DKV 20060623 Czopek, A; Byrtus, H; Kolaczkowski, M; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Wesolowska, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46192019 104150685 CHEMBL1098287 ZINC49088056 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572205 Clc1cccc(c1)N1CCN(CCCN2C(=O)NC3(CCCc4ccccc34)C2=O)CC1 InChI=1S/C25H29ClN4O2/c26-20-8-3-9-21(18-20)29-16-14-28(15-17-29)12-5-13-30-23(31)25(27-24(30)32)11-4-7-19-6-1-2-10-22(19)25/h1-3,6,8-10,18H,4-5,7,11-17H2,(H,27,32) NKVHCNUWDQBXDY-UHFFFAOYSA-N 50316325 CHEMBL1096620::rac-1-{3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl}-3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphthalene]-2,5-dione D(2) dopamine receptor Rattus norvegicus 1800 ChEMBL 10.1016/j.ejmech.2009.11.053 10.7270/Q2WM1DKV 20060623 Czopek, A; Byrtus, H; Kolaczkowski, M; Pawlowski, M; Dybala, M; Nowak, G; Tatarczynska, E; Wesolowska, A; Chojnacka-Wojcik, E Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46192021 104150686 CHEMBL1096620 ZINC49114252 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50601752 CCCCN1CCC(COC(=O)c2ccc(N)c(OC)c2)CC1 InChI=1S/C18H28N2O3/c1-3-4-9-20-10-7-14(8-11-20)13-23-18(21)15-5-6-16(19)17(12-15)22-2/h5-6,12,14H,3-4,7-11,13,19H2,1-2H3 DZZIAERGLDKTBT-UHFFFAOYSA-N 50327861 (1-Butylpiperidin-4-yl)methyl 4-Amino-3-methoxybenzoate::CHEMBL1258452 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm100668r 10.7270/Q2BR8SD7 20812727 Xu, R; Hong, J; Morse, CL; Pike, VW National Institute of Mental Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50327861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50327861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 49783415 123106976 CHEMBL1258452 ZINC64548966 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585526 Cc1cccc(c1)N1CCN(CCCCCCN2CCN(CC2)c2ccccc2)CC1 InChI=1S/C27H40N4/c1-25-10-9-13-27(24-25)31-22-18-29(19-23-31)15-8-3-2-7-14-28-16-20-30(21-17-28)26-11-5-4-6-12-26/h4-6,9-13,24H,2-3,7-8,14-23H2,1H3 AWPASOZUABXVOH-UHFFFAOYSA-N 50322369 1-phenyl-4-(6-(4-m-tolylpiperazin-1-yl)hexyl)piperazine::CHEMBL1172734 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322369&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11640376 104143898 CHEMBL1172734 ZINC35984164 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585527 C(CCCN1CCN(CC1)c1ccnc2ccccc12)CCN1CCN(CC1)c1ccccc1 InChI=1S/C29H39N5/c1(8-16-31-18-22-33(23-19-31)26-10-4-3-5-11-26)2-9-17-32-20-24-34(25-21-32)29-14-15-30-28-13-7-6-12-27(28)29/h3-7,10-15H,1-2,8-9,16-25H2 AEQHEVDDTLOOMD-UHFFFAOYSA-N 50322370 4-(4-(6-(4-phenylpiperazin-1-yl)hexyl)piperazin-1-yl)quinoline::CHEMBL1173017 D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322370&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11539823 104143899 CHEMBL1173017 ZINC34631347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585528 Cc1cccc(c1)N1CCN(CCCCCCN2CCN(CC2)c2ccccn2)CC1 InChI=1S/C26H39N5/c1-24-9-8-10-25(23-24)30-19-15-28(16-20-30)13-6-2-3-7-14-29-17-21-31(22-18-29)26-11-4-5-12-27-26/h4-5,8-12,23H,2-3,6-7,13-22H2,1H3 GXAJAEYMTGMWDK-UHFFFAOYSA-N 50322371 1-(pyridin-2-yl)-4-(6-(4-m-tolylpiperazin-1-yl)hexyl)piperazine::CHEMBL1173018 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322371&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11661752 104143900 CHEMBL1173018 ZINC38210083 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585529 Cc1cccc(c1)N1CCN(CCCCCCN2CCN(CC2)c2cccc(C)n2)CC1 InChI=1S/C27H41N5/c1-24-9-7-11-26(23-24)31-19-15-29(16-20-31)13-5-3-4-6-14-30-17-21-32(22-18-30)27-12-8-10-25(2)28-27/h7-12,23H,3-6,13-22H2,1-2H3 PBQPCCMEDMVKBH-UHFFFAOYSA-N 50322372 1-(6-methylpyridin-2-yl)-4-(6-(4-m-tolylpiperazin-1-yl)hexyl)piperazine::CHEMBL1173077 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322372&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11524900 104143901 CHEMBL1173077 ZINC53314426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585530 COc1cccc(c1)N1CCN(CCCCCCN2CCN(CC2)c2cccc(Cl)c2)CC1 InChI=1S/C27H39ClN4O/c1-33-27-11-7-10-26(23-27)32-20-16-30(17-21-32)13-5-3-2-4-12-29-14-18-31(19-15-29)25-9-6-8-24(28)22-25/h6-11,22-23H,2-5,12-21H2,1H3 LHRSLSNYJPWXLS-UHFFFAOYSA-N 50322373 1-(3-chlorophenyl)-4-(6-(4-(3-methoxyphenyl)piperazin-1-yl)hexyl)piperazine::CHEMBL1173143 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322373 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322373&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11648483 104143902 CHEMBL1173143 ZINC35998779 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585531 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 319 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585532 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585533 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585534 Cc1cccc(c1)N1CCN(CCCCNC(=O)c2cc3ccccc3o2)CC1 InChI=1S/C24H29N3O2/c1-19-7-6-9-21(17-19)27-15-13-26(14-16-27)12-5-4-11-25-24(28)23-18-20-8-2-3-10-22(20)29-23/h2-3,6-10,17-18H,4-5,11-16H2,1H3,(H,25,28) DIJKUIXRAWOVGJ-UHFFFAOYSA-N 50265376 CHEMBL496739::N-(4-(4-(m-Tolyl)piperazin-1-yl)butyl)benzo[b]furan-2-carboxamide::N-(4-(4-m-tolylpiperazin-1-yl)butyl)benzofuran-2-carboxamide D(2) dopamine receptor Rattus norvegicus 4.5 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265376&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11696813 104113153 CHEMBL496739 ZINC26954229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599300 CCCN(CCC)CCc1cccc2NC(=O)Cc12 InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19) UHSKFQJFRQCDBE-UHFFFAOYSA-N 50020680 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE D(2) dopamine receptor Rattus norvegicus 2674 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5095 103931441 8888 CHEMBL589 DB00268 7295 C07564 ZINC00002041 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599301 CCCN(CCN1CCN(CC1)c1ccccc1)[C@@H]1CCc2ccc(O)cc2C1 InChI=1S/C25H35N3O/c1-2-12-27(24-10-8-21-9-11-25(29)20-22(21)19-24)16-13-26-14-17-28(18-15-26)23-6-4-3-5-7-23/h3-7,9,11,20,24,29H,2,8,10,12-19H2,1H3/t24-/m1/s1 POVCSYONXDMZKL-XMMPIXPASA-N 50273937 (+)-(R)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::(R)-7-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL456825::D-315 D(2) dopamine receptor Rattus norvegicus 40.6 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273937&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44588498 104117900 CHEMBL456825 ZINC22924455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599302 CCCN(CCN1CCN(CC1)c1nccc2ccccc12)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C25H34N6S/c1-2-11-30(20-7-8-22-23(18-20)32-25(26)28-22)15-12-29-13-16-31(17-14-29)24-21-6-4-3-5-19(21)9-10-27-24/h3-6,9-10,20H,2,7-8,11-18H2,1H3,(H2,26,28)/t20-/m0/s1 SNMHDHJEXUFVCO-FQEVSTJZSA-N 50303791 (-)-(S)-N6-(2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine::CHEMBL571992 D(2) dopamine receptor Rattus norvegicus 269 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45486330 104158152 CHEMBL571992 ZINC45283305 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599303 CCCN(CCN1CCN(CC1)c1ccccn1)C1CCc2ccc(O)cc2C1 InChI=1S/C24H34N4O/c1-2-11-27(22-8-6-20-7-9-23(29)19-21(20)18-22)15-12-26-13-16-28(17-14-26)24-5-3-4-10-25-24/h3-5,7,9-10,19,22,29H,2,6,8,11-18H2,1H3 KIBICQVMFUXHBE-UHFFFAOYSA-N 50326725 7-(propyl(2-(4-(pyridin-2-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL1254689 D(2) dopamine receptor Rattus norvegicus 103 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326725&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 46919028 123105840 CHEMBL1254689 ZINC64251805 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599304 CCCN(CCN1CCN(CC1)c1ncccn1)C1CCc2ccc(O)cc2C1 InChI=1S/C23H33N5O/c1-2-10-27(21-6-4-19-5-7-22(29)18-20(19)17-21)14-11-26-12-15-28(16-13-26)23-24-8-3-9-25-23/h3,5,7-9,18,21,29H,2,4,6,10-17H2,1H3 QPFPLXIMWCZMQV-UHFFFAOYSA-N 50326726 7-(propyl(2-(4-(pyrimidin-2-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL1254772 D(2) dopamine receptor Rattus norvegicus 165 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52949476 123105841 CHEMBL1254772 ZINC64415649 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599305 CCCN(CCN1CCN(CC1)c1cccnc1)C1CCc2ccc(O)cc2C1 InChI=1S/C24H34N4O/c1-2-10-27(22-7-5-20-6-8-24(29)18-21(20)17-22)14-11-26-12-15-28(16-13-26)23-4-3-9-25-19-23/h3-4,6,8-9,18-19,22,29H,2,5,7,10-17H2,1H3 LFLWSALOEDMVRA-UHFFFAOYSA-N 50326727 7-(propyl(2-(4-(pyridin-3-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL1254773 D(2) dopamine receptor Rattus norvegicus 21.7 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326727&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52943355 123105842 CHEMBL1254773 ZINC64415651 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599306 CCCN(CCN1CCN(CC1)c1ccncc1)C1CCc2ccc(O)cc2C1 InChI=1S/C24H34N4O/c1-2-11-27(23-5-3-20-4-6-24(29)19-21(20)18-23)15-12-26-13-16-28(17-14-26)22-7-9-25-10-8-22/h4,6-10,19,23,29H,2-3,5,11-18H2,1H3 JBAHBJRMOBCAFP-UHFFFAOYSA-N 50326728 7-(propyl(2-(4-(pyridin-4-yl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL1254861 D(2) dopamine receptor Rattus norvegicus 68.3 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326728&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52948252 123105843 CHEMBL1254861 ZINC64415807 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599307 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1cccnc1)C1CCc2ccc(O)cc2C1 InChI=1S/C30H38N4O/c1-2-14-33(29-11-7-25-8-12-30(35)22-27(25)21-29)18-15-32-16-19-34(20-17-32)28-9-5-24(6-10-28)26-4-3-13-31-23-26/h3-6,8-10,12-13,22-23,29,35H,2,7,11,14-21H2,1H3 BEZGSFSQVUCZFC-UHFFFAOYSA-N 50326729 CHEMBL1254862::rac-7-(propyl(2-(4-(4-(pyridin-3-yl)phenyl)-piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol D(2) dopamine receptor Rattus norvegicus 59.1 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326729&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52949517 123105844 CHEMBL1254862 ZINC64415787 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599308 CCCN(CCN1CCN(CC1)c1ccc(I)cc1)C1CCc2ccc(O)cc2C1 InChI=1S/C25H34IN3O/c1-2-11-28(24-7-3-20-4-10-25(30)19-21(20)18-24)15-12-27-13-16-29(17-14-27)23-8-5-22(26)6-9-23/h4-6,8-10,19,24,30H,2-3,7,11-18H2,1H3 DFALWOBBEKTUMZ-UHFFFAOYSA-N 50326730 7-((2-(4-(4-iodophenyl)piperazin-1-yl)-ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL1254946 D(2) dopamine receptor Rattus norvegicus 46.4 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326730&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52942220 123105845 CHEMBL1254946 ZINC64459452 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599309 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccccc1)C1CCc2c(O)cccc2C1 InChI=1S/C31H39N3O/c1-2-17-33(29-15-16-30-27(24-29)9-6-10-31(30)35)21-18-32-19-22-34(23-20-32)28-13-11-26(12-14-28)25-7-4-3-5-8-25/h3-14,29,35H,2,15-24H2,1H3 KLFRUTOTKKRLHR-UHFFFAOYSA-N 50326731 (-)-6-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::CHEMBL1254947 D(2) dopamine receptor Rattus norvegicus 53.6 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326731&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52941006 123105846 CHEMBL1254947 ZINC64416924 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599310 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccncc1)C1CCc2c(O)cccc2C1 InChI=1S/C30H38N4O/c1-2-16-33(28-10-11-29-26(23-28)4-3-5-30(29)35)20-17-32-18-21-34(22-19-32)27-8-6-24(7-9-27)25-12-14-31-15-13-25/h3-9,12-15,28,35H,2,10-11,16-23H2,1H3 SRCFLOVZPHBHHM-UHFFFAOYSA-N 50326732 (-)-6-(propyl(2-(4-(4-(pyridin-4-yl)-phenyl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::CHEMBL1255028 D(2) dopamine receptor Rattus norvegicus 13.2 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326732&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52948338 123105847 CHEMBL1255028 ZINC64436343 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599311 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccncc1)C1CCc2ccc(O)cc2C1 InChI=1S/C30H38N4O/c1-2-15-33(29-9-5-25-6-10-30(35)23-27(25)22-29)19-16-32-17-20-34(21-18-32)28-7-3-24(4-8-28)26-11-13-31-14-12-26/h3-4,6-8,10-14,23,29,35H,2,5,9,15-22H2,1H3 AQQDXLPBCNHRIE-UHFFFAOYSA-N 50326733 (+)-7-(propyl(2-(4-(4-(pyridin-4-yl)-phenyl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::(-)-7-(propyl(2-(4-(4-(pyridin-4yl)-phenyl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL1253769 D(2) dopamine receptor Rattus norvegicus 399 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326733&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52949727 123105848 CHEMBL1253769 ZINC64391307 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599312 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccncc1)C1CCc2ccc(O)cc2C1 InChI=1S/C30H38N4O/c1-2-15-33(29-9-5-25-6-10-30(35)23-27(25)22-29)19-16-32-17-20-34(21-18-32)28-7-3-24(4-8-28)26-11-13-31-14-12-26/h3-4,6-8,10-14,23,29,35H,2,5,9,15-22H2,1H3 AQQDXLPBCNHRIE-UHFFFAOYSA-N 50326733 (+)-7-(propyl(2-(4-(4-(pyridin-4-yl)-phenyl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::(-)-7-(propyl(2-(4-(4-(pyridin-4yl)-phenyl)piperazin-1-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL1253769 D(2) dopamine receptor Rattus norvegicus 399 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326733&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52949727 123105848 CHEMBL1253769 ZINC64391307 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599332 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 311 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599334 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccccc1)C1CCc2ccc(O)cc2C1 InChI=1S/C31H39N3O/c1-2-16-33(30-14-10-27-11-15-31(35)24-28(27)23-30)20-17-32-18-21-34(22-19-32)29-12-8-26(9-13-29)25-6-4-3-5-7-25/h3-9,11-13,15,24,30,35H,2,10,14,16-23H2,1H3 MHNXSUUHELFLSP-UHFFFAOYSA-N 50326734 7-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydro naphthalen-2-ol::7-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL1253770 D(2) dopamine receptor Rattus norvegicus 64.1 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16038360 123105849 CHEMBL1253770 ZINC34875786 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599336 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccccc1)C1CCc2ccc(O)cc2C1 InChI=1S/C31H39N3O/c1-2-16-33(30-14-10-27-11-15-31(35)24-28(27)23-30)20-17-32-18-21-34(22-19-32)29-12-8-26(9-13-29)25-6-4-3-5-7-25/h3-9,11-13,15,24,30,35H,2,10,14,16-23H2,1H3 MHNXSUUHELFLSP-UHFFFAOYSA-N 50326734 7-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydro naphthalen-2-ol::7-((2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL1253770 D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16038360 123105849 CHEMBL1253770 ZINC34875786 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50599340 CCCN(CCC)C1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3 MDBWEQVKJDMEMK-UHFFFAOYSA-N 50020221 (-)-5-hydroxy-2-(dipropylamino)tetralin::(-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::5-hydroxy-2-(dipropylamino)tetralin::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (DP-5-ADTN)::CHEMBL273273 D(2) dopamine receptor Rattus norvegicus 58.8 ChEMBL 10.1016/j.bmc.2010.06.025 10.7270/Q2W37WJ9 20605099 Ghosh, B; Antonio, T; Gopishetty, B; Reith, M; Dutta, A Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 172267 103931135 CHEMBL273273 128 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585600 C(CCCN1CCN(CC1)c1ccccc1)CCN1CCN(CC1)c1ccccc1 InChI=1S/C26H38N4/c1(9-15-27-17-21-29(22-18-27)25-11-5-3-6-12-25)2-10-16-28-19-23-30(24-20-28)26-13-7-4-8-14-26/h3-8,11-14H,1-2,9-10,15-24H2 ORESESSHUCUUFK-UHFFFAOYSA-N 50322374 1,6-bis(4-phenylpiperazin-1-yl)hexane::CHEMBL1172205 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11567667 104143903 CHEMBL1172205 ZINC35826839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585601 Cc1cccc(c1)N1CCN(CCCCCCN2CCN(CC2)c2cccc(C)c2)CC1 InChI=1S/C28H42N4/c1-25-9-7-11-27(23-25)31-19-15-29(16-20-31)13-5-3-4-6-14-30-17-21-32(22-18-30)28-12-8-10-26(2)24-28/h7-12,23-24H,3-6,13-22H2,1-2H3 CQEUVRXXXLSTIL-UHFFFAOYSA-N 50322375 1,6-bis(4-m-tolylpiperazin-1-yl)hexane::CHEMBL1172204 D(2) dopamine receptor Rattus norvegicus 70 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322375&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11669239 104143904 CHEMBL1172204 ZINC38216590 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585602 COc1cccc(c1)N1CCN(CCCCCCN2CCN(CC2)c2cccc(OC)c2)CC1 InChI=1S/C28H42N4O2/c1-33-27-11-7-9-25(23-27)31-19-15-29(16-20-31)13-5-3-4-6-14-30-17-21-32(22-18-30)26-10-8-12-28(24-26)34-2/h7-12,23-24H,3-6,13-22H2,1-2H3 IMWNCWRNMUKPGO-UHFFFAOYSA-N 50322376 1,6-bis(4-(3-methoxyphenyl)piperazin-1-yl)hexane::CHEMBL1172206 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322376&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11568942 104143905 CHEMBL1172206 ZINC35833901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585603 Clc1cccc(c1)N1CCN(CCCCCCN2CCN(CC2)c2cccc(Cl)c2)CC1 InChI=1S/C26H36Cl2N4/c27-23-7-5-9-25(21-23)31-17-13-29(14-18-31)11-3-1-2-4-12-30-15-19-32(20-16-30)26-10-6-8-24(28)22-26/h5-10,21-22H,1-4,11-20H2 YWGRWBCJUGEEBA-UHFFFAOYSA-N 50322377 1,6-bis(4-(3-chlorophenyl)piperazin-1-yl)hexane::CHEMBL1171823 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11641429 104143906 CHEMBL1171823 ZINC35985316 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585604 C(CCCN1CCN(CC1)c1ccccn1)CCN1CCN(CC1)c1ccccn1 InChI=1S/C24H36N6/c1(7-13-27-15-19-29(20-16-27)23-9-3-5-11-25-23)2-8-14-28-17-21-30(22-18-28)24-10-4-6-12-26-24/h3-6,9-12H,1-2,7-8,13-22H2 OSEVIYJKDQCRJK-UHFFFAOYSA-N 50322378 1,6-bis(4-(pyridin-2-yl)piperazin-1-yl)hexane::CHEMBL1171644 D(2) dopamine receptor Rattus norvegicus 159 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11524350 104143907 CHEMBL1171644 ZINC53298110 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585605 C(CCCN1CCN(CC1)c1ccccn1)CCN1CCN(CC1)c1ccccc1 InChI=1S/C25H37N5/c1(8-14-27-16-20-29(21-17-27)24-10-4-3-5-11-24)2-9-15-28-18-22-30(23-19-28)25-12-6-7-13-26-25/h3-7,10-13H,1-2,8-9,14-23H2 BWMDINMAJBXMLE-UHFFFAOYSA-N 50322379 1-phenyl-4-(6-(4-(pyridin-2-yl)piperazin-1-yl)hexyl)piperazine::CHEMBL1171646 D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322379&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11704191 104143908 CHEMBL1171646 ZINC38279943 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50585606 Cc1cccc(n1)N1CCN(CCCCCCN2CCN(CC2)c2ccccc2)CC1 InChI=1S/C26H39N5/c1-24-10-9-13-26(27-24)31-22-18-29(19-23-31)15-8-3-2-7-14-28-16-20-30(21-17-28)25-11-5-4-6-12-25/h4-6,9-13H,2-3,7-8,14-23H2,1H3 RZIJMFBERNFJML-UHFFFAOYSA-N 50322380 1-(6-methylpyridin-2-yl)-4-(6-(4-phenylpiperazin-1-yl)hexyl)piperazine::CHEMBL1171824 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm100294b 10.7270/Q28P60QP 20481570 Butini, S; Campiani, G; Franceschini, S; Trotta, F; Kumar, V; Guarino, E; Borrelli, G; Fiorini, I; Novellino, E; Fattorusso, C; Persico, M; Orteca, N; Sandager-Nielsen, K; Jacobsen, TA; Madsen, K; Scheel-Kruger, J; Gemma, S Universita di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11604196 104143909 CHEMBL1171824 ZINC35919698 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50601671 CCCCN1CCC(COC(=O)c2cc(Cl)c(NC)c3OCCOc23)CC1 InChI=1S/C20H29ClN2O4/c1-3-4-7-23-8-5-14(6-9-23)13-27-20(24)15-12-16(21)17(22-2)19-18(15)25-10-11-26-19/h12,14,22H,3-11,13H2,1-2H3 WKWADEWWLCVVLF-UHFFFAOYSA-N 50327860 (1-Butylpiperidin-4-yl)methyl 7-chloro-8-(methylamino)-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate::CHEMBL1258223 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm100668r 10.7270/Q2BR8SD7 20812727 Xu, R; Hong, J; Morse, CL; Pike, VW National Institute of Mental Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50327860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50327860&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 49783209 123106975 CHEMBL1258223 ZINC64548813 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50601721 CCCCN1CCC(COC(=O)c2cc(F)c(N)c3OCCOc23)CC1 InChI=1S/C19H27FN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3 WLHFUBIRAHRPHA-UHFFFAOYSA-N 50327863 (1-Butylpiperidin-4-yl)methyl 8-Amino-7-fluoro-2,3-dihydrobenzo[b][1,4]dioxine-5-carboxylate::CHEMBL1258671 D(2) dopamine receptor Rattus norvegicus 615 ChEMBL 10.1021/jm100668r 10.7270/Q2BR8SD7 20812727 Xu, R; Hong, J; Morse, CL; Pike, VW National Institute of Mental Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50327863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50327863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 49783419 123106978 CHEMBL1258671 ZINC64548828 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50620016 OC1(CCN(CCCC(OC(=O)CCCc2ccccc2)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C31H35ClFNO3/c32-27-15-13-26(14-16-27)31(36)19-22-34(23-20-31)21-5-9-29(25-11-17-28(33)18-12-25)37-30(35)10-4-8-24-6-2-1-3-7-24/h1-3,6-7,11-18,29,36H,4-5,8-10,19-23H2 BYFXZIUNDKEGTH-UHFFFAOYSA-N 50335605 (+/-)-4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butyl4-phenylbutanoate::CHEMBL1649601 D(2) dopamine receptor Rattus norvegicus >5000 ChEMBL 10.1016/j.ejmech.2010.10.012 10.7270/Q2FF3SN9 21055848 Marrazzo, A; Fiorito, J; Zappala, L; Prezzavento, O; Ronsisvalle, S; Pasquinucci, L; Scoto, GM; Bernardini, R; Ronsisvalle, G University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50335605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50335605&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24894137 125085707 CHEMBL1649601 ZINC66104711 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50620017 OC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1 InChI=1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2 WNZBBTJFOIOEMP-UHFFFAOYSA-N 50064946 4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol::CHEMBL1036::Hydroxyhaloperidol D(2) dopamine receptor Rattus norvegicus 232 ChEMBL 10.1016/j.ejmech.2010.10.012 10.7270/Q2FF3SN9 21055848 Marrazzo, A; Fiorito, J; Zappala, L; Prezzavento, O; Ronsisvalle, S; Pasquinucci, L; Scoto, GM; Bernardini, R; Ronsisvalle, G University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 119265 103959901 CHEMBL1036 ZINC04257980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50620018 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2.1 ChEMBL 10.1016/j.ejmech.2010.10.012 10.7270/Q2FF3SN9 21055848 Marrazzo, A; Fiorito, J; Zappala, L; Prezzavento, O; Ronsisvalle, S; Pasquinucci, L; Scoto, GM; Bernardini, R; Ronsisvalle, G University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638600 COc1ccccc1C1CCN(Cc2nc3ccccc3n2C)CC1 InChI=1S/C21H25N3O/c1-23-19-9-5-4-8-18(19)22-21(23)15-24-13-11-16(12-14-24)17-7-3-6-10-20(17)25-2/h3-10,16H,11-15H2,1-2H3 MJDLYRJRCRLNGE-UHFFFAOYSA-N 50343295 2-((4-(2-Methoxy-phenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo[d]imidazole::CHEMBL1774101 D(2) dopamine receptor Rattus norvegicus 426 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343295&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51356569 131346231 CHEMBL1774101 ZINC71316782 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638601 Cn1c(CN2CCC(CC2)c2ccccc2F)nc2ccccc12 InChI=1S/C20H22FN3/c1-23-19-9-5-4-8-18(19)22-20(23)14-24-12-10-15(11-13-24)16-6-2-3-7-17(16)21/h2-9,15H,10-14H2,1H3 AMADNKXMEDYTCS-UHFFFAOYSA-N 50343299 2-((4-(2-Fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo-[d]imidazole::2-((4-(2-fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo[d]imidazole::CHEMBL607689 D(2) dopamine receptor Rattus norvegicus 93 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24815439 131346235 CHEMBL607689 ZINC45387802 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638603 Cn1c(CN2CCC(CC2)c2ccc(Cl)cc2F)nc2ccccc12 InChI=1S/C20H21ClFN3/c1-24-19-5-3-2-4-18(19)23-20(24)13-25-10-8-14(9-11-25)16-7-6-15(21)12-17(16)22/h2-7,12,14H,8-11,13H2,1H3 ZOSDMAHANBIICB-UHFFFAOYSA-N 50343305 2-((4-(4-Chloro-2-fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo[d]imidazole::CHEMBL1774107 D(2) dopamine receptor Rattus norvegicus 91 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343305&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23725156 131346241 CHEMBL1774107 ZINC71317497 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638604 Cn1c(CN2CCC(CC2)c2ccc(cc2)C(F)(F)F)nc2ccccc12 InChI=1S/C21H22F3N3/c1-26-19-5-3-2-4-18(19)25-20(26)14-27-12-10-16(11-13-27)15-6-8-17(9-7-15)21(22,23)24/h2-9,16H,10-14H2,1H3 SCFTWYRRDFJRSO-UHFFFAOYSA-N 50343306 1-methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-benzo[d]imidazole::CHEMBL593745 D(2) dopamine receptor Rattus norvegicus 561 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343306&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24815976 131346242 CHEMBL593745 ZINC45348327 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638605 Cn1c(CN2CCC(CC2)c2ccc(cc2)C(F)(F)F)nc2ncccc12 InChI=1S/C20H21F3N4/c1-26-17-3-2-10-24-19(17)25-18(26)13-27-11-8-15(9-12-27)14-4-6-16(7-5-14)20(21,22)23/h2-7,10,15H,8-9,11-13H2,1H3 JJJUTEJMSCWLKG-UHFFFAOYSA-N 50343308 1-Methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-imidazo[4,5-b]pyridine::CHEMBL1774108 D(2) dopamine receptor Rattus norvegicus 404 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343308&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25008615 131346244 CHEMBL1774108 ZINC71319046 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638606 Cn1c(CN2CCC(CC2)c2ccc(cc2)C(F)(F)F)nc2cnccc12 InChI=1S/C20H21F3N4/c1-26-18-6-9-24-12-17(18)25-19(26)13-27-10-7-15(8-11-27)14-2-4-16(5-3-14)20(21,22)23/h2-6,9,12,15H,7-8,10-11,13H2,1H3 OPQVLALJVICCEZ-UHFFFAOYSA-N 50343309 1-Methyl-2-((4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-imidazo[4,5-c]pyridine::CHEMBL1774109 D(2) dopamine receptor Rattus norvegicus 671 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343309&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25008437 131346245 CHEMBL1774109 ZINC71319382 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638607 COc1cc(ccc1C1CCN(Cc2nc3ncccc3n2C)CC1)C(F)(F)F InChI=1S/C21H23F3N4O/c1-27-17-4-3-9-25-20(17)26-19(27)13-28-10-7-14(8-11-28)16-6-5-15(21(22,23)24)12-18(16)29-2/h3-6,9,12,14H,7-8,10-11,13H2,1-2H3 OQNTWJNDKUVZAQ-UHFFFAOYSA-N 50343312 2-((4-(2-Methoxy-4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine::CHEMBL1774112 D(2) dopamine receptor Rattus norvegicus 2430 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343312&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25008958 131346248 CHEMBL1774112 ZINC71330229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638608 Cn1c(CN2CCC(CC2)c2ccc(cc2F)C(F)(F)F)nc2ncccc12 InChI=1S/C20H20F4N4/c1-27-17-3-2-8-25-19(17)26-18(27)12-28-9-6-13(7-10-28)15-5-4-14(11-16(15)21)20(22,23)24/h2-5,8,11,13H,6-7,9-10,12H2,1H3 KOJZZXZYGJZWMH-UHFFFAOYSA-N 50343313 2-((4-(2-Fluoro-4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine::CHEMBL1774221 D(2) dopamine receptor Rattus norvegicus 1780 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343313&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51357399 131346249 CHEMBL1774221 ZINC71317979 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638609 Cn1c(CN2CCC(CC2)c2ccc(OC(F)(F)F)cc2F)nc2ncccc12 InChI=1S/C20H20F4N4O/c1-27-17-3-2-8-25-19(17)26-18(27)12-28-9-6-13(7-10-28)15-5-4-14(11-16(15)21)29-20(22,23)24/h2-5,8,11,13H,6-7,9-10,12H2,1H3 WVBOYSGJAJVORN-UHFFFAOYSA-N 50343314 2-((4-(2-Fluoro-4-(trifluoromethoxy)phenyl)piperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine::CHEMBL1774222 D(2) dopamine receptor Rattus norvegicus 1180 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51357400 131346250 CHEMBL1774222 ZINC71329700 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638610 C[C@@H]1C[C@@H](CCN1Cc1nc2ncccc2n1C)c1ccc(cc1)C(F)(F)F InChI=1S/C21H23F3N4/c1-14-12-16(15-5-7-17(8-6-15)21(22,23)24)9-11-28(14)13-19-26-20-18(27(19)2)4-3-10-25-20/h3-8,10,14,16H,9,11-13H2,1-2H3/t14-,16-/m1/s1 BOZVHERQYJVRDG-GDBMZVCRSA-N 50343316 CHEMBL1774224::cis-1-methyl-2-(((2R,4R)-2-methyl-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-imidazo[4,5-b]pyridine D(2) dopamine receptor Rattus norvegicus 589 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343316&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51356571 131346252 CHEMBL1774224 ZINC71317156 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638611 Cn1c(CN2[C@H]3CC[C@@H]2CC(C3)c2ccc(cc2)C(F)(F)F)nc2ncccc12 InChI=1S/C22H23F3N4/c1-28-19-3-2-10-26-21(19)27-20(28)13-29-17-8-9-18(29)12-15(11-17)14-4-6-16(7-5-14)22(23,24)25/h2-7,10,15,17-18H,8-9,11-13H2,1H3/t15?,17-,18+ IZHSVHBZIDFPRT-ZNXRZULTSA-N 50343317 1-methyl-2-(((1R,5S)-3-(4-(trifluoromethyl)phenyl)-8-azabicyclo[3.2.1]octan-8-yl)methyl)-1H-imidazo[4,5-b]pyridine::CHEMBL1774225 D(2) dopamine receptor Rattus norvegicus 355 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343317&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51356833 131346253 CHEMBL1774225 ZINC71319409 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638612 Cn1c(CN2CC[C@@H](c3ccc(cc3)C(F)(F)F)C(C)(C)C2)nc2ncccc12 InChI=1S/C22H25F3N4/c1-21(2)14-29(13-19-27-20-18(28(19)3)5-4-11-26-20)12-10-17(21)15-6-8-16(9-7-15)22(23,24)25/h4-9,11,17H,10,12-14H2,1-3H3/t17-/m0/s1 KHCXQMDIHQPUSZ-KRWDZBQOSA-N 50343318 (S)-2-((3,3-dimethyl-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine::CHEMBL1774226 D(2) dopamine receptor Rattus norvegicus >2800 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343318&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54580322 131346254 CHEMBL1774226 ZINC71330235 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638613 C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(cc1)C(F)(F)F InChI=1S/C21H23F3N4/c1-14-12-28(13-19-26-20-18(27(19)2)4-3-10-25-20)11-9-17(14)15-5-7-16(8-6-15)21(22,23)24/h3-8,10,14,17H,9,11-13H2,1-2H3/t14-,17+/m0/s1 IORJDNYKXIMYCK-WMLDXEAASA-N 50343319 CHEMBL1774227::cis-1-methyl-2-(((3R,4R)-3-methyl-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-imidazo[4,5-b]pyridine::cis-rac-1-methyl-2-(((3R,4R)-3-methyl-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-imidazo[4,5-b]pyridine D(2) dopamine receptor Rattus norvegicus >2800 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51357934 131346255 CHEMBL1774227 ZINC71317946 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638614 C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(cc1)C(F)(F)F InChI=1S/C21H23F3N4/c1-14-12-28(13-19-26-20-18(27(19)2)4-3-10-25-20)11-9-17(14)15-5-7-16(8-6-15)21(22,23)24/h3-8,10,14,17H,9,11-13H2,1-2H3/t14-,17+/m0/s1 IORJDNYKXIMYCK-WMLDXEAASA-N 50343319 CHEMBL1774227::cis-1-methyl-2-(((3R,4R)-3-methyl-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-imidazo[4,5-b]pyridine::cis-rac-1-methyl-2-(((3R,4R)-3-methyl-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-imidazo[4,5-b]pyridine D(2) dopamine receptor Rattus norvegicus >2800 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51357934 131346255 CHEMBL1774227 ZINC71317946 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638615 C[C@@H]1CN(Cc2nc3ncccc3n2C)CC[C@@H]1c1ccc(cc1)C(F)(F)F InChI=1S/C21H23F3N4/c1-14-12-28(13-19-26-20-18(27(19)2)4-3-10-25-20)11-9-17(14)15-5-7-16(8-6-15)21(22,23)24/h3-8,10,14,17H,9,11-13H2,1-2H3/t14-,17+/m1/s1 IORJDNYKXIMYCK-PBHICJAKSA-N 50343320 CHEMBL1774228::cis-1-methyl-2-(((3S,4S)-3-methyl-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-imidazo[4,5-b]pyridine D(2) dopamine receptor Rattus norvegicus >2800 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51353704 131346256 CHEMBL1774228 ZINC71297078 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638616 C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(Cl)cc1F InChI=1S/C20H22ClFN4/c1-13-11-26(9-7-15(13)16-6-5-14(21)10-17(16)22)12-19-24-20-18(25(19)2)4-3-8-23-20/h3-6,8,10,13,15H,7,9,11-12H2,1-2H3/t13-,15+/m0/s1 HUDWYYYFRVUKIA-DZGCQCFKSA-N 50343321 CHEMBL1774229::cis-2-(((3R,4R)-4-(4-chloro-2-fluorophenyl)-3-methylpiperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine D(2) dopamine receptor Rattus norvegicus 1620 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51357935 131346257 CHEMBL1774229 ZINC71316141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638617 COc1cc(ccc1[C@@H]1CCN(Cc2nc3ncccc3n2C)C[C@@H]1C)C(F)(F)F InChI=1S/C22H25F3N4O/c1-14-12-29(13-20-27-21-18(28(20)2)5-4-9-26-21)10-8-16(14)17-7-6-15(22(23,24)25)11-19(17)30-3/h4-7,9,11,14,16H,8,10,12-13H2,1-3H3/t14-,16+/m0/s1 XTGROMAGIGWBCC-GOEBONIOSA-N 50343323 CHEMBL1774231::cis-2-(((3R,4R)-4-(2-methoxy-4-(trifluoromethyl)phenyl)-3-methylpiperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine D(2) dopamine receptor Rattus norvegicus >5260 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51357936 131346259 CHEMBL1774231 ZINC71329372 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638618 C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(cc1F)C(F)(F)F InChI=1S/C21H22F4N4/c1-13-11-29(12-19-27-20-18(28(19)2)4-3-8-26-20)9-7-15(13)16-6-5-14(10-17(16)22)21(23,24)25/h3-6,8,10,13,15H,7,9,11-12H2,1-2H3/t13-,15+/m0/s1 FVYBXACUKLZYDM-DZGCQCFKSA-N 50343325 CHEMBL1774233::cis-2-(((3R,4R)-4-(2-fluoro-4-(trifluoromethyl)phenyl)-3-methylpiperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine D(2) dopamine receptor Rattus norvegicus >5260 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51357937 131346261 CHEMBL1774233 ZINC71318369 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638619 C[C@H]1CN(Cc2nc3ncccc3n2C)CC[C@H]1c1ccc(OC(F)(F)F)cc1F InChI=1S/C21H22F4N4O/c1-13-11-29(12-19-27-20-18(28(19)2)4-3-8-26-20)9-7-15(13)16-6-5-14(10-17(16)22)30-21(23,24)25/h3-6,8,10,13,15H,7,9,11-12H2,1-2H3/t13-,15+/m0/s1 CQTZXNPIJZSXKK-DZGCQCFKSA-N 50343327 CHEMBL1774235::cis-2-(((3R,4R)-4-(2-fluoro-4-(trifluoromethoxy)phenyl)-3-methylpiperidin-1-yl)methyl)-1-methyl-1H-imidazo[4,5-b]pyridine D(2) dopamine receptor Rattus norvegicus >4680 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44178197 131346263 CHEMBL1774235 ZINC71329333 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50638602 Cn1c(CN2CCC(CC2)c2ccc(F)cc2)nc2ccccc12 InChI=1S/C20H22FN3/c1-23-19-5-3-2-4-18(19)22-20(23)14-24-12-10-16(11-13-24)15-6-8-17(21)9-7-15/h2-9,16H,10-14H2,1H3 YEJCZFQPJIMMCF-UHFFFAOYSA-N 50343301 2-((4-(4-Fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo-[d]imidazole::CHEMBL1774103 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm101414h 10.7270/Q2222V3C 21366332 Zhang, L; Brodney, MA; Candler, J; Doran, AC; Duplantier, AJ; Efremov, IV; Evrard, E; Kraus, K; Ganong, AH; Haas, JA; Hanks, AN; Jenza, K; Lazzaro, JT; Maklad, N; McCarthy, SA; Qian, W; Rogers, BN; Rottas, MD; Schmidt, CJ; Siuciak, JA; Tingley, FD; Zhang, AQ Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343301&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24815355 131346237 CHEMBL1774103 ZINC71318646 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647637 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 11.5 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647638 CN1CCc2cc(SC[C@H](N)C(O)=O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H22N2O4S/c1-22-5-4-11-6-12(27-9-14(21)20(25)26)8-13-17(11)15(22)7-10-2-3-16(23)19(24)18(10)13/h2-3,6,8,14-15,23-24H,4-5,7,9,21H2,1H3,(H,25,26)/t14-,15+/m0/s1 QCEAYDMNZTWNGV-LSDHHAIUSA-N 50347556 CHEMBL1802231 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53328719 136354242 CHEMBL1802231 C05726 ZINC72105437 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647639 CN1CCc2cc(SC[C@@H](N)C(O)=O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H22N2O4S/c1-22-5-4-11-6-12(27-9-14(21)20(25)26)8-13-17(11)15(22)7-10-2-3-16(23)19(24)18(10)13/h2-3,6,8,14-15,23-24H,4-5,7,9,21H2,1H3,(H,25,26)/t14-,15-/m1/s1 QCEAYDMNZTWNGV-HUUCEWRRSA-N 50347557 CHEMBL1802232 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53328721 136354243 CHEMBL1802232 ZINC72109060 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647640 CN1CCc2cc(SCCN)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H22N2O2S/c1-21-6-4-12-8-13(24-7-5-20)10-14-17(12)15(21)9-11-2-3-16(22)19(23)18(11)14/h2-3,8,10,15,22-23H,4-7,9,20H2,1H3/t15-/m1/s1 JNVDABKFDDZRON-OAHLLOKOSA-N 50347558 CHEMBL1802233 D(2) dopamine receptor Rattus norvegicus 9.6 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327663 136354244 CHEMBL1802233 ZINC72105045 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647641 CN1CCc2cc(Sc3ccccc3)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C23H21NO2S/c1-24-10-9-15-11-17(27-16-5-3-2-4-6-16)13-18-21(15)19(24)12-14-7-8-20(25)23(26)22(14)18/h2-8,11,13,19,25-26H,9-10,12H2,1H3/t19-/m1/s1 KQUKOXMDOZGIMI-LJQANCHMSA-N 50347559 CHEMBL1802234 D(2) dopamine receptor Rattus norvegicus 580 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15548770 136354245 CHEMBL1802234 ZINC72106489 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647642 COC(=O)[C@@H](N)CSc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C21H24N2O4S/c1-23-6-5-12-7-13(28-10-15(22)21(26)27-2)9-14-18(12)16(23)8-11-3-4-17(24)20(25)19(11)14/h3-4,7,9,15-16,24-25H,5-6,8,10,22H2,1-2H3/t15-,16+/m0/s1 MRAUUEIDBJJIOT-JKSUJKDBSA-N 50347560 CHEMBL1802235 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327665 136354246 CHEMBL1802235 C03317 ZINC72105046 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647643 CN1CCc2cc(SCCC(O)=O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H21NO4S/c1-21-6-4-12-8-13(26-7-5-17(23)24)10-14-18(12)15(21)9-11-2-3-16(22)20(25)19(11)14/h2-3,8,10,15,22,25H,4-7,9H2,1H3,(H,23,24)/t15-/m1/s1 WJDARRQQNQNTEX-OAHLLOKOSA-N 50347561 CHEMBL1802236 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53328901 136354247 CHEMBL1802236 ZINC72105987 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647644 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647645 CN1CCc2cc(SC[C@H](N)C(O)=O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H22N2O4S/c1-22-5-4-11-6-12(27-9-14(21)20(25)26)8-13-17(11)15(22)7-10-2-3-16(23)19(24)18(10)13/h2-3,6,8,14-15,23-24H,4-5,7,9,21H2,1H3,(H,25,26)/t14-,15+/m0/s1 QCEAYDMNZTWNGV-LSDHHAIUSA-N 50347556 CHEMBL1802231 D(2) dopamine receptor Rattus norvegicus 211 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53328719 136354242 CHEMBL1802231 C05726 ZINC72105437 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647646 CN1CCc2cc(SC[C@@H](N)C(O)=O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H22N2O4S/c1-22-5-4-11-6-12(27-9-14(21)20(25)26)8-13-17(11)15(22)7-10-2-3-16(23)19(24)18(10)13/h2-3,6,8,14-15,23-24H,4-5,7,9,21H2,1H3,(H,25,26)/t14-,15-/m1/s1 QCEAYDMNZTWNGV-HUUCEWRRSA-N 50347557 CHEMBL1802232 D(2) dopamine receptor Rattus norvegicus 198 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53328721 136354243 CHEMBL1802232 ZINC72109060 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647647 CN1CCc2cc(SCCN)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H22N2O2S/c1-21-6-4-12-8-13(24-7-5-20)10-14-17(12)15(21)9-11-2-3-16(22)19(23)18(11)14/h2-3,8,10,15,22-23H,4-7,9,20H2,1H3/t15-/m1/s1 JNVDABKFDDZRON-OAHLLOKOSA-N 50347558 CHEMBL1802233 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327663 136354244 CHEMBL1802233 ZINC72105045 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647648 CN1CCc2cc(Sc3ccccc3)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C23H21NO2S/c1-24-10-9-15-11-17(27-16-5-3-2-4-6-16)13-18-21(15)19(24)12-14-7-8-20(25)23(26)22(14)18/h2-8,11,13,19,25-26H,9-10,12H2,1H3/t19-/m1/s1 KQUKOXMDOZGIMI-LJQANCHMSA-N 50347559 CHEMBL1802234 D(2) dopamine receptor Rattus norvegicus 820 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15548770 136354245 CHEMBL1802234 ZINC72106489 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647649 COC(=O)[C@@H](N)CSc1cc2CCN(C)[C@@H]3Cc4ccc(O)c(O)c4-c(c1)c23 InChI=1S/C21H24N2O4S/c1-23-6-5-12-7-13(28-10-15(22)21(26)27-2)9-14-18(12)16(23)8-11-3-4-17(24)20(25)19(11)14/h3-4,7,9,15-16,24-25H,5-6,8,10,22H2,1-2H3/t15-,16+/m0/s1 MRAUUEIDBJJIOT-JKSUJKDBSA-N 50347560 CHEMBL1802235 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53327665 136354246 CHEMBL1802235 C03317 ZINC72105046 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647650 CN1CCc2cc(SCCC(O)=O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H21NO4S/c1-21-6-4-12-8-13(26-7-5-17(23)24)10-14-18(12)15(21)9-11-2-3-16(22)20(25)19(11)14/h2-3,8,10,15,22,25H,4-7,9H2,1H3,(H,23,24)/t15-/m1/s1 WJDARRQQNQNTEX-OAHLLOKOSA-N 50347561 CHEMBL1802236 D(2) dopamine receptor Rattus norvegicus 148 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53328901 136354247 CHEMBL1802236 ZINC72105987 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647651 CN1CCc2c3[C@H]1Cc1ccc(O)c(O)c1-c3cc1SCCC(=O)c21 InChI=1S/C20H19NO3S/c1-21-6-4-11-18-12(9-16-19(11)14(22)5-7-25-16)17-10(8-13(18)21)2-3-15(23)20(17)24/h2-3,9,13,23-24H,4-8H2,1H3/t13-/m1/s1 UOWFASPLMHQBNL-CYBMUJFWSA-N 50347562 CHEMBL1802237 D(2) dopamine receptor Rattus norvegicus 383 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53328903 136354248 CHEMBL1802237 ZINC72105076 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647660 CN1CCc2c3[C@H]1Cc1ccc(O)c(O)c1-c3cc1SCCC(=O)c21 InChI=1S/C20H19NO3S/c1-21-6-4-11-18-12(9-16-19(11)14(22)5-7-25-16)17-10(8-13(18)21)2-3-15(23)20(17)24/h2-3,9,13,23-24H,4-8H2,1H3/t13-/m1/s1 UOWFASPLMHQBNL-CYBMUJFWSA-N 50347562 CHEMBL1802237 D(2) dopamine receptor Rattus norvegicus 415 ChEMBL 10.1016/j.ejmech.2011.04.028 10.7270/Q2X34XTG 21550699 Reinart, R; Gyulai, Z; Berenyi, S; Antus, S; Vonk, A; Rinken, A; Sipos, A University of Tartu http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53328903 136354248 CHEMBL1802237 ZINC72105076 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50645368 O=c1n(OCCCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12 InChI=1S/C24H25N5O2/c30-24-21-10-3-4-11-22(21)25-26-29(24)31-18-6-13-27-14-16-28(17-15-27)23-12-5-8-19-7-1-2-9-20(19)23/h1-5,7-12H,6,13-18H2 DMXFORFTCSBZNW-UHFFFAOYSA-N 50346380 3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propoxy)benzo[d][1,2,3]triazin-4(3H)-one::CHEMBL1783349 D(2) dopamine receptor Rattus norvegicus 85.4 ChEMBL 10.1016/j.ejmech.2011.03.001 10.7270/Q2M32W4J 21440338 Fiorino, F; Magli, E; Perissutti, E; Severino, B; Frecentese, F; Esposito, A; De Angelis, F; Incisivo, GM; Massarelli, P; Nencini, C; Di Gennaro, E; Budillon, A; Di Cintio, A; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53304670 131349311 CHEMBL1783349 ZINC71282388 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50645369 O=C1C2C3CC(C=C3)C2C(=O)N1OCCCN1CCN(CC1)c1cccc2ccccc12 InChI=1S/C26H29N3O3/c30-25-23-19-9-10-20(17-19)24(23)26(31)29(25)32-16-4-11-27-12-14-28(15-13-27)22-8-3-6-18-5-1-2-7-21(18)22/h1-3,5-10,19-20,23-24H,4,11-17H2 RUFAUUMYKFPZQN-UHFFFAOYSA-N 50346375 4-[3-[4-(naphthalen)piperazin-1-yl]propoxy]-4-aza-tricyclo [5.2.1.02,6]dec-8-ene-3,5-dione::CHEMBL1783351 D(2) dopamine receptor Rattus norvegicus 263 ChEMBL 10.1016/j.ejmech.2011.03.001 10.7270/Q2M32W4J 21440338 Fiorino, F; Magli, E; Perissutti, E; Severino, B; Frecentese, F; Esposito, A; De Angelis, F; Incisivo, GM; Massarelli, P; Nencini, C; Di Gennaro, E; Budillon, A; Di Cintio, A; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346375&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54582356 131349306 CHEMBL1783351 ZINC71294641 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50645370 N#CNC(=NCCCN1CCN(CC1)c1cccc2ccccc12)c1ccncc1 InChI=1S/C24H26N6/c25-19-28-24(21-9-12-26-13-10-21)27-11-4-14-29-15-17-30(18-16-29)23-8-3-6-20-5-1-2-7-22(20)23/h1-3,5-10,12-13H,4,11,14-18H2,(H,27,28) AAKZKXONERDTDD-UHFFFAOYSA-N 50346381 CHEMBL1783352::N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)isonicotinamidine D(2) dopamine receptor Rattus norvegicus 1600 ChEMBL 10.1016/j.ejmech.2011.03.001 10.7270/Q2M32W4J 21440338 Fiorino, F; Magli, E; Perissutti, E; Severino, B; Frecentese, F; Esposito, A; De Angelis, F; Incisivo, GM; Massarelli, P; Nencini, C; Di Gennaro, E; Budillon, A; Di Cintio, A; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346381&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53304674 131349312 CHEMBL1783352 ZINC71295540 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50645371 O=c1n(CCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12 InChI=1S/C23H23N5O/c29-23-20-9-3-4-10-21(20)24-25-28(23)17-14-26-12-15-27(16-13-26)22-11-5-7-18-6-1-2-8-19(18)22/h1-11H,12-17H2 JQQXUGWNTUCGOI-UHFFFAOYSA-N 50346374 3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethyl)benzo[d][1,2,3]triazin-4(3H)-one::CHEMBL1783346 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2011.03.001 10.7270/Q2M32W4J 21440338 Fiorino, F; Magli, E; Perissutti, E; Severino, B; Frecentese, F; Esposito, A; De Angelis, F; Incisivo, GM; Massarelli, P; Nencini, C; Di Gennaro, E; Budillon, A; Di Cintio, A; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24777378 131349305 CHEMBL1783346 ZINC71295555 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50645372 O=c1n(CCCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12 InChI=1S/C24H25N5O/c30-24-21-10-3-4-11-22(21)25-26-29(24)14-6-13-27-15-17-28(18-16-27)23-12-5-8-19-7-1-2-9-20(19)23/h1-5,7-12H,6,13-18H2 VTPLXEUSMDJJMM-UHFFFAOYSA-N 50346376 3-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)benzo[d][1,2,3]triazin-4(3H)-one::CHEMBL1783347 D(2) dopamine receptor Rattus norvegicus >10001 ChEMBL 10.1016/j.ejmech.2011.03.001 10.7270/Q2M32W4J 21440338 Fiorino, F; Magli, E; Perissutti, E; Severino, B; Frecentese, F; Esposito, A; De Angelis, F; Incisivo, GM; Massarelli, P; Nencini, C; Di Gennaro, E; Budillon, A; Di Cintio, A; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346376&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24777372 131349307 CHEMBL1783347 ZINC71296175 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50645373 O=c1n(OCCN2CCN(CC2)c2cccc3ccccc23)nnc2ccccc12 InChI=1S/C23H23N5O2/c29-23-20-9-3-4-10-21(20)24-25-28(23)30-17-16-26-12-14-27(15-13-26)22-11-5-7-18-6-1-2-8-19(18)22/h1-11H,12-17H2 GTEJVFXEOPITIQ-UHFFFAOYSA-N 50346379 3-(2-(4-(naphthalen-1-yl)piperazin-1-yl)ethoxy)benzo[d][1,2,3]triazin-4(3H)-one::CHEMBL1783348 D(2) dopamine receptor Rattus norvegicus >10002 ChEMBL 10.1016/j.ejmech.2011.03.001 10.7270/Q2M32W4J 21440338 Fiorino, F; Magli, E; Perissutti, E; Severino, B; Frecentese, F; Esposito, A; De Angelis, F; Incisivo, GM; Massarelli, P; Nencini, C; Di Gennaro, E; Budillon, A; Di Cintio, A; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346379&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53304669 131349310 CHEMBL1783348 ZINC71295800 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50645374 O=C1C2C3CC(C=C3)C2C(=O)N1OCCN1CCN(CC1)c1cccc2ccccc12 InChI=1S/C25H27N3O3/c29-24-22-18-8-9-19(16-18)23(22)25(30)28(24)31-15-14-26-10-12-27(13-11-26)21-7-3-5-17-4-1-2-6-20(17)21/h1-9,18-19,22-23H,10-16H2 XVVQTXOUNBDUSY-UHFFFAOYSA-N 50346377 4-[2-[4-(naphthalen)piperazin-1-yl]ethoxy]-4-aza-tricyclo [5.2.1.02,6]dec-8-ene-3,5-dione::CHEMBL1783350 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2011.03.001 10.7270/Q2M32W4J 21440338 Fiorino, F; Magli, E; Perissutti, E; Severino, B; Frecentese, F; Esposito, A; De Angelis, F; Incisivo, GM; Massarelli, P; Nencini, C; Di Gennaro, E; Budillon, A; Di Cintio, A; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54585250 131349308 CHEMBL1783350 ZINC71295400 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50645375 N#CNC(=NCCCN1CCN(CC1)c1cccc2ccccc12)c1ccccn1 InChI=1S/C24H26N6/c25-19-28-24(22-10-3-4-12-26-22)27-13-6-14-29-15-17-30(18-16-29)23-11-5-8-20-7-1-2-9-21(20)23/h1-5,7-12H,6,13-18H2,(H,27,28) YWTAKDXVVAFCSC-UHFFFAOYSA-N 50346378 CHEMBL1783353::N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)picolinamidine D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2011.03.001 10.7270/Q2M32W4J 21440338 Fiorino, F; Magli, E; Perissutti, E; Severino, B; Frecentese, F; Esposito, A; De Angelis, F; Incisivo, GM; Massarelli, P; Nencini, C; Di Gennaro, E; Budillon, A; Di Cintio, A; Santagada, V; Caliendo, G Universit£ di Napoli Federico II http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53304828 131349309 CHEMBL1783353 ZINC71296118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706718 Oc1c2CCCn2c(=O)n1CCCCNCc1ccc2ccccc2c1 InChI=1S/C21H25N3O2/c25-20-19-8-5-13-23(19)21(26)24(20)12-4-3-11-22-15-16-9-10-17-6-1-2-7-18(17)14-16/h1-2,6-7,9-10,14,22,25H,3-5,8,11-13,15H2 MLTZOWOQUKMZCO-UHFFFAOYSA-N 50359425 CHEMBL1926730 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359425&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91930423 136963449 CHEMBL1926730 ZINC73199004 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706719 Oc1c2CCCn2c(=O)n1CCCCNCCc1cccc2ccccc12 InChI=1S/C22H27N3O2/c26-21-20-11-6-16-24(20)22(27)25(21)15-4-3-13-23-14-12-18-9-5-8-17-7-1-2-10-19(17)18/h1-2,5,7-10,23,26H,3-4,6,11-16H2 CIKAFPKBAOFJTC-UHFFFAOYSA-N 50359426 CHEMBL1926729 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359426&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90752437 136963450 CHEMBL1926729 ZINC73277181 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706806 Oc1csc(=O)n1CCCCCCCCNCC1CCc2ccccc2O1 InChI=1S/C21H30N2O3S/c24-20-16-27-21(25)23(20)14-8-4-2-1-3-7-13-22-15-18-12-11-17-9-5-6-10-19(17)26-18/h5-6,9-10,16,18,22,24H,1-4,7-8,11-15H2 BRKZWBXBNWKPOJ-UHFFFAOYSA-N 50359427 CHEMBL1926760 D(2) dopamine receptor Rattus norvegicus 410 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90762067 136963451 CHEMBL1926760 ZINC35907397 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706807 Oc1csc(=O)n1CCCCCCNCC1CCc2ccccc2O1 InChI=1S/C19H26N2O3S/c22-18-14-25-19(23)21(18)12-6-2-1-5-11-20-13-16-10-9-15-7-3-4-8-17(15)24-16/h3-4,7-8,14,16,20,22H,1-2,5-6,9-13H2 ARHJQEBWDUYAPL-UHFFFAOYSA-N 50359428 CHEMBL1926759 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359428&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91500378 136963452 CHEMBL1926759 ZINC73275093 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706808 Oc1csc(=O)n1CCCCCNCC1CCc2ccccc2O1 InChI=1S/C18H24N2O3S/c21-17-13-24-18(22)20(17)11-5-1-4-10-19-12-15-9-8-14-6-2-3-7-16(14)23-15/h2-3,6-7,13,15,19,21H,1,4-5,8-12H2 BECZXSSRKPETSS-UHFFFAOYSA-N 50359429 CHEMBL1926758 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359429&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91188017 136963453 CHEMBL1926758 ZINC73280374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706809 Oc1c2CCCn2c(=O)n1Cc1cccc(CNCC2CCc3ccccc3O2)c1 InChI=1S/C24H27N3O3/c28-23-21-8-4-12-26(21)24(29)27(23)16-18-6-3-5-17(13-18)14-25-15-20-11-10-19-7-1-2-9-22(19)30-20/h1-3,5-7,9,13,20,25,28H,4,8,10-12,14-16H2 WHSPEDOVAKRTFO-UHFFFAOYSA-N 50359430 CHEMBL1926757 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359430&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90949029 136963454 CHEMBL1926757 ZINC34661136 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706810 Oc1c2CCCn2c(=O)n1Cc1ccc(CNCC2CCc3ccccc3O2)cc1 InChI=1S/C24H27N3O3/c28-23-21-5-3-13-26(21)24(29)27(23)16-18-9-7-17(8-10-18)14-25-15-20-12-11-19-4-1-2-6-22(19)30-20/h1-2,4,6-10,20,25,28H,3,5,11-16H2 ANLXKXZPJFWNAG-UHFFFAOYSA-N 50359431 CHEMBL1926756 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90996303 136963455 CHEMBL1926756 ZINC35943255 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50707947 COc1ccccc1N1CCN(CCCN=C(NC#N)c2ccccn2)CC1 InChI=1S/C21H26N6O/c1-28-20-9-3-2-8-19(20)27-15-13-26(14-16-27)12-6-11-24-21(25-17-22)18-7-4-5-10-23-18/h2-5,7-10H,6,11-16H2,1H3,(H,24,25) QDINHVYVESYLKG-UHFFFAOYSA-N 50359954 CHEMBL1927088 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2011.11.023 10.7270/Q29S1RFN 22133459 Fiorino, F; Severino, B; Magli, E; Perissutti, E; Frecentese, F; Esposito, A; Incisivo, GM; Ciano, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56971026 136963978 CHEMBL1927088 ZINC73389814 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50707952 COc1ccc(cc1)N1CCN(CCCN=C(NC#N)c2ccccn2)CC1 InChI=1S/C21H26N6O/c1-28-19-8-6-18(7-9-19)27-15-13-26(14-16-27)12-4-11-24-21(25-17-22)20-5-2-3-10-23-20/h2-3,5-10H,4,11-16H2,1H3,(H,24,25) CVZMDIHZFOVDBI-UHFFFAOYSA-N 50359955 CHEMBL1927089 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2011.11.023 10.7270/Q29S1RFN 22133459 Fiorino, F; Severino, B; Magli, E; Perissutti, E; Frecentese, F; Esposito, A; Incisivo, GM; Ciano, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56971027 136963979 CHEMBL1927089 ZINC82156796 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50707953 CCOc1ccccc1N1CCN(CCCN=C(NC#N)c2ccccn2)CC1 InChI=1S/C22H28N6O/c1-2-29-21-10-4-3-9-20(21)28-16-14-27(15-17-28)13-7-12-25-22(26-18-23)19-8-5-6-11-24-19/h3-6,8-11H,2,7,12-17H2,1H3,(H,25,26) NHUMMWMTKRGTLW-UHFFFAOYSA-N 50359956 CHEMBL1927090 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2011.11.023 10.7270/Q29S1RFN 22133459 Fiorino, F; Severino, B; Magli, E; Perissutti, E; Frecentese, F; Esposito, A; Incisivo, GM; Ciano, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56971028 136963980 CHEMBL1927090 ZINC82154952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50707954 Cc1cccc(N2CCN(CCCN=C(NC#N)c3ccccn3)CC2)c1C InChI=1S/C22H28N6/c1-18-7-5-9-21(19(18)2)28-15-13-27(14-16-28)12-6-11-25-22(26-17-23)20-8-3-4-10-24-20/h3-5,7-10H,6,11-16H2,1-2H3,(H,25,26) JHFSEBODCGAYRF-UHFFFAOYSA-N 50359958 CHEMBL1927092 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2011.11.023 10.7270/Q29S1RFN 22133459 Fiorino, F; Severino, B; Magli, E; Perissutti, E; Frecentese, F; Esposito, A; Incisivo, GM; Ciano, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56971030 136963982 CHEMBL1927092 ZINC82154957 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50707955 Clc1cccc(c1)N1CCN(CCCN=C(NC#N)c2ccccn2)CC1 InChI=1S/C20H23ClN6/c21-17-5-3-6-18(15-17)27-13-11-26(12-14-27)10-4-9-24-20(25-16-22)19-7-1-2-8-23-19/h1-3,5-8,15H,4,9-14H2,(H,24,25) OZUQLMIRFSQYTM-UHFFFAOYSA-N 50359960 CHEMBL1927094 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2011.11.023 10.7270/Q29S1RFN 22133459 Fiorino, F; Severino, B; Magli, E; Perissutti, E; Frecentese, F; Esposito, A; Incisivo, GM; Ciano, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56971032 136963984 CHEMBL1927094 ZINC82151133 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50707956 FC(F)(F)c1cccc(c1)N1CCN(CCCN=C(NC#N)c2ccccn2)CC1 InChI=1S/C21H23F3N6/c22-21(23,24)17-5-3-6-18(15-17)30-13-11-29(12-14-30)10-4-9-27-20(28-16-25)19-7-1-2-8-26-19/h1-3,5-8,15H,4,9-14H2,(H,27,28) OXXWZHKBQVSZRB-UHFFFAOYSA-N 50359961 CHEMBL1927095 D(2) dopamine receptor Rattus norvegicus 83.7 ChEMBL 10.1016/j.ejmech.2011.11.023 10.7270/Q29S1RFN 22133459 Fiorino, F; Severino, B; Magli, E; Perissutti, E; Frecentese, F; Esposito, A; Incisivo, GM; Ciano, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56971261 136963985 CHEMBL1927095 ZINC82151136 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50707957 N#CNC(=NCCCN1CCN(CC1)c1ncccn1)c1ccccn1 InChI=1S/C18H22N8/c19-15-24-17(16-5-1-2-6-20-16)21-9-4-10-25-11-13-26(14-12-25)18-22-7-3-8-23-18/h1-3,5-8H,4,9-14H2,(H,21,24) DLTDRUFHRWCSNO-UHFFFAOYSA-N 50359962 CHEMBL1927096 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2011.11.023 10.7270/Q29S1RFN 22133459 Fiorino, F; Severino, B; Magli, E; Perissutti, E; Frecentese, F; Esposito, A; Incisivo, GM; Ciano, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359962&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56971262 136963986 CHEMBL1927096 ZINC82156560 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50707958 N#CNC(=NCCCN1CCN(CC1)c1ccccn1)c1ccccn1 InChI=1S/C19H23N7/c20-16-24-19(17-6-1-3-8-21-17)23-10-5-11-25-12-14-26(15-13-25)18-7-2-4-9-22-18/h1-4,6-9H,5,10-15H2,(H,23,24) RYRUUOFCTXRLPJ-UHFFFAOYSA-N 50359963 CHEMBL1927097 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2011.11.023 10.7270/Q29S1RFN 22133459 Fiorino, F; Severino, B; Magli, E; Perissutti, E; Frecentese, F; Esposito, A; Incisivo, GM; Ciano, A; Massarelli, P; Nencini, C; Santagada, V; Caliendo, G Universit£ di Napoli"Federico II" http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359963&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56971263 136963987 CHEMBL1927097 ZINC82156563 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706811 Oc1c2CCCn2c(=O)n1C\C=C\CNCC1CCc2ccccc2O1 InChI=1S/C20H25N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-4,6,8,16,21,24H,5,7,9-14H2/b4-3+ CXIGAAUKJDPSQU-ONEGZZNKSA-N 50359434 CHEMBL1926753 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91930426 136963458 CHEMBL1926753 ZINC35825604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706812 Oc1c2CCCn2c(=O)n1CCCCCCNCC1CCc2ccccc2O1 InChI=1S/C22H31N3O3/c26-21-19-9-7-15-24(19)22(27)25(21)14-6-2-1-5-13-23-16-18-12-11-17-8-3-4-10-20(17)28-18/h3-4,8,10,18,23,26H,1-2,5-7,9,11-16H2 KFEOCDXIJZFQIE-UHFFFAOYSA-N 50359436 CHEMBL1926751 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90838408 136963460 CHEMBL1926751 ZINC73275720 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706813 Oc1c2CCCn2c(=O)n1CCCCCNCC1CCc2ccccc2O1 InChI=1S/C21H29N3O3/c25-20-18-8-6-14-23(18)21(26)24(20)13-5-1-4-12-22-15-17-11-10-16-7-2-3-9-19(16)27-17/h2-3,7,9,17,22,25H,1,4-6,8,10-15H2 HSBHWVSZXUGNDP-UHFFFAOYSA-N 50359437 CHEMBL1926686 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359437&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91046420 136963461 CHEMBL1926686 ZINC73277206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706814 Oc1c2CCCn2c(=O)n1CCCNCC1CCc2ccccc2O1 InChI=1S/C19H25N3O3/c23-18-16-6-3-11-21(16)19(24)22(18)12-4-10-20-13-15-9-8-14-5-1-2-7-17(14)25-15/h1-2,5,7,15,20,23H,3-4,6,8-13H2 QBJIXXNWWVDIGD-UHFFFAOYSA-N 50359438 CHEMBL1926750 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91360146 136963462 CHEMBL1926750 ZINC35845956 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706815 Oc1csc(=O)n1CCCCNCC1CCc2ccccc2O1 InChI=1S/C17H22N2O3S/c20-16-12-23-17(21)19(16)10-4-3-9-18-11-14-8-7-13-5-1-2-6-15(13)22-14/h1-2,5-6,12,14,18,20H,3-4,7-11H2 OAIPWPJDJGTZKB-UHFFFAOYSA-N 50359439 CHEMBL1926749 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90973056 136963463 CHEMBL1926749 ZINC73258851 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706816 Oc1c2CSCn2c(=O)n1CCCCNCC1CCc2ccccc2O1 InChI=1S/C19H25N3O3S/c23-18-16-12-26-13-22(16)19(24)21(18)10-4-3-9-20-11-15-8-7-14-5-1-2-6-17(14)25-15/h1-2,5-6,15,20,23H,3-4,7-13H2 SGZHZVDWIAURCO-UHFFFAOYSA-N 50359416 CHEMBL1926748 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359416&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91930421 136963440 CHEMBL1926748 ZINC73258842 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706817 Oc1c2CCSn2c(=O)n1CCCCNCC1CCc2ccccc2O1 InChI=1S/C19H25N3O3S/c23-18-16-9-12-26-22(16)19(24)21(18)11-4-3-10-20-13-15-8-7-14-5-1-2-6-17(14)25-15/h1-2,5-6,15,20,23H,3-4,7-13H2 NPGJSXDYSSLKJT-UHFFFAOYSA-N 50359417 CHEMBL1926747 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359417&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91930422 136963441 CHEMBL1926747 ZINC73258621 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706818 O=C1CN(CCCCNCC2CCc3ccccc3O2)C(=O)C2CCCCN12 InChI=1S/C22H31N3O3/c26-21-16-24(22(27)19-8-3-5-14-25(19)21)13-6-4-12-23-15-18-11-10-17-7-1-2-9-20(17)28-18/h1-2,7,9,18-19,23H,3-6,8,10-16H2 JCQOGVDSEZNVDJ-UHFFFAOYSA-N 50359418 CHEMBL1926746 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11560071 136963442 CHEMBL1926746 ZINC35815547 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706819 O=C1CN(CCCCNCC2CCc3ccccc3O2)C(=O)C2CCCN12 InChI=1S/C21H29N3O3/c25-20-15-23(21(26)18-7-5-13-24(18)20)12-4-3-11-22-14-17-10-9-16-6-1-2-8-19(16)27-17/h1-2,6,8,17-18,22H,3-5,7,9-15H2 DSCQYJWJCPNZPX-UHFFFAOYSA-N 50359419 CHEMBL1926745 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359419&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56850658 136963443 CHEMBL1926745 ZINC73280366 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706820 Oc1c2CCCCn2c(=O)n1CCCCNCC1CCc2ccccc2O1 InChI=1S/C21H29N3O3/c25-20-18-8-3-5-13-23(18)21(26)24(20)14-6-4-12-22-15-17-11-10-16-7-1-2-9-19(16)27-17/h1-2,7,9,17,22,25H,3-6,8,10-15H2 TUCNIAHIRFQJSH-UHFFFAOYSA-N 50359420 CHEMBL1926744 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359420&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91400956 136963444 CHEMBL1926744 ZINC73197700 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706821 Oc1c2CCCn2c(=O)n1CCCCNC[C@@H]1CCc2ccccc2O1 InChI=1S/C20H27N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-2,6,8,16,21,24H,3-5,7,9-14H2/t16-/m0/s1 UAMOZWUMVFJFDW-INIZCTEOSA-N 50359421 CHEMBL1926735 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91407908 136963445 CHEMBL1926735 ZINC73198271 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706822 Oc1c2CCCn2c(=O)n1CCCCNC[C@H]1CCc2ccccc2O1 InChI=1S/C20H27N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-2,6,8,16,21,24H,3-5,7,9-14H2/t16-/m1/s1 UAMOZWUMVFJFDW-MRXNPFEDSA-N 50359422 CHEMBL1926734 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91432022 136963446 CHEMBL1926734 ZINC73198270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706823 Oc1c2CCCn2c(=O)n1CCCCNC[C@@H]1CCc2ccccc2O1 InChI=1S/C20H27N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-2,6,8,16,21,24H,3-5,7,9-14H2/t16-/m0/s1 UAMOZWUMVFJFDW-INIZCTEOSA-N 50359421 CHEMBL1926735 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91407908 136963445 CHEMBL1926735 ZINC73198271 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706824 Oc1c2CCCn2c(=O)n1CCCCNCc1ccc2ccccc2n1 InChI=1S/C20H24N4O2/c25-19-18-8-5-13-23(18)20(26)24(19)12-4-3-11-21-14-16-10-9-15-6-1-2-7-17(15)22-16/h1-2,6-7,9-10,21,25H,3-5,8,11-14H2 DSMQQQLBFHYIQT-UHFFFAOYSA-N 50359423 CHEMBL1926732 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359423&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91143227 136963447 CHEMBL1926732 ZINC38278803 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50706825 Oc1c2CCCn2c(=O)n1CCCCNCCc1ccc2ccccc2c1 InChI=1S/C22H27N3O2/c26-21-20-8-5-15-24(20)22(27)25(21)14-4-3-12-23-13-11-17-9-10-18-6-1-2-7-19(18)16-17/h1-2,6-7,9-10,16,23,26H,3-5,8,11-15H2 QUJIOTKSUKNCSB-UHFFFAOYSA-N 50359424 CHEMBL1926731 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm2007886 10.7270/Q2R49R61 22029386 Marco, I; Valhondo, M; Martin-Fontecha, M; Vazquez-Villa, H; Del Rio, J; Planas, A; Sagredo, O; Ramos, JA; Torrecillas, IR; Pardo, L; Frechilla, D; Benhamu, B; Lopez-Rodriguez, ML Universidad Complutense de Madrid http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359424&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91035728 136963448 CHEMBL1926731 ZINC73258615 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723596 C1CC(=CCC1N1CCN(CC1)c1ccccn1)c1cccs1 InChI=1S/C19H23N3S/c1-2-10-20-19(5-1)22-13-11-21(12-14-22)17-8-6-16(7-9-17)18-4-3-15-23-18/h1-6,10,15,17H,7-9,11-14H2 CXONTQZSVJEICK-UHFFFAOYSA-N 50281605 1-Pyridin-2-yl-4-(4-thiophen-2-yl-cyclohex-3-enyl)-piperazine::CHEMBL157087::PD-135188 D(2) dopamine receptor Rattus norvegicus 352 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281605&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15079634 104123279 CHEMBL157087 ZINC27712873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723601 C1CC(=CCC1N1CCN(CC1)c1ccccn1)c1ccccn1 InChI=1S/C20H24N4/c1-3-11-21-19(5-1)17-7-9-18(10-8-17)23-13-15-24(16-14-23)20-6-2-4-12-22-20/h1-7,11-12,18H,8-10,13-16H2 MCTSZRVXVCAAHY-UHFFFAOYSA-N 50281607 1-Pyridin-2-yl-4-(4-pyridin-2-yl-cyclohex-3-enyl)-piperazine::CHEMBL422187::PD-135222 D(2) dopamine receptor Rattus norvegicus 1180 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281607&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15079632 104123281 CHEMBL422187 ZINC27715411 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723607 C(CN1CCN(CC1)c1ccccn1)C1CCC(=CC1)c1ccccn1 InChI=1S/C22H28N4/c1-3-12-23-21(5-1)20-9-7-19(8-10-20)11-14-25-15-17-26(18-16-25)22-6-2-4-13-24-22/h1-6,9,12-13,19H,7-8,10-11,14-18H2 KTGXACIWWLVCPX-UHFFFAOYSA-N 50281609 1-Pyridin-2-yl-4-[2-(4-pyridin-2-yl-cyclohex-3-enyl)-ethyl]-piperazine::CHEMBL346075::PD-135540 D(2) dopamine receptor Rattus norvegicus 128 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281609&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15079633 104123283 CHEMBL346075 ZINC27715200 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723608 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723609 C(C1CCC(=CC1)c1cccs1)N1CCN(CC1)c1ccccn1 InChI=1S/C20H25N3S/c1-2-10-21-20(5-1)23-13-11-22(12-14-23)16-17-6-8-18(9-7-17)19-4-3-15-24-19/h1-5,8,10,15,17H,6-7,9,11-14,16H2 QFAVGTOUBHVISF-UHFFFAOYSA-N 50281608 1-Pyridin-2-yl-4-(4-thiophen-2-yl-cyclohex-3-enylmethyl)-piperazine::CHEMBL349994::PD-135146 D(2) dopamine receptor Rattus norvegicus 2430 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281608&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15079636 104123282 CHEMBL349994 ZINC27715399 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723611 C1CC(=CCC1N1CCN(CC1)c1ccccn1)c1ccccc1 InChI=1S/C21H25N3/c1-2-6-18(7-3-1)19-9-11-20(12-10-19)23-14-16-24(17-15-23)21-8-4-5-13-22-21/h1-9,13,20H,10-12,14-17H2 MBOHGQXYZVXXQF-UHFFFAOYSA-N 50281610 1-(4-Phenyl-cyclohex-3-enyl)-4-pyridin-2-yl-piperazine::CHEMBL157422::PD-135478 D(2) dopamine receptor Rattus norvegicus 600 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281610&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15079635 104123284 CHEMBL157422 ZINC27712503 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723614 C(CN1CCN(CC1)c1ccccn1)C1CCC(=CC1)c1cccs1 InChI=1S/C21H27N3S/c1-2-11-22-21(5-1)24-15-13-23(14-16-24)12-10-18-6-8-19(9-7-18)20-4-3-17-25-20/h1-5,8,11,17-18H,6-7,9-10,12-16H2 AAFWZBAPCZZXNP-UHFFFAOYSA-N 50281611 1-Pyridin-2-yl-4-[2-(4-thiophen-2-yl-cyclohex-3-enyl)-ethyl]-piperazine::CHEMBL346940::PD-135111 D(2) dopamine receptor Rattus norvegicus 436 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281611&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15079637 104123285 CHEMBL346940 ZINC27711901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50583536 CN(CC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1)CC([O-])=O InChI=1S/C19H20F3NO3/c1-23(13-18(24)25)12-11-17(14-5-3-2-4-6-14)26-16-9-7-15(8-10-16)19(20,21)22/h2-10,17H,11-13H2,1H3,(H,24,25)/p-1/t17-/m1/s1 KZWQAWBTWNPFPW-QGZVFWFLSA-M 50421506 CHEMBL61861::ORG-24598 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1016/s0960-894x(01)00355-9 10.7270/Q2X0687Q 11454468 Brown, A; Carlyle, I; Clark, J; Hamilton, W; Gibson, S; McGarry, G; McEachen, S; Rae, D; Thorn, S; Walker, G Organon Research and Development Group http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421506&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16759590 164150381 CHEMBL61861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723800 CCCN(CCC)C1Cc2cnn3cccc(C1)c23 InChI=1S/C16H23N3/c1-3-7-18(8-4-2)15-10-13-6-5-9-19-16(13)14(11-15)12-17-19/h5-6,9,12,15H,3-4,7-8,10-11H2,1-2H3 NGFQETPADWIYMH-UHFFFAOYSA-N 50282001 (4,5-Dihydro-3H-pyrazolo[4,5,1-ij]quinolin-4-yl)-dipropyl-amine::CHEMBL34025 D(2) dopamine receptor Rattus norvegicus 260 ChEMBL 10.1016/S0960-894X(00)80003-7 10.7270/Q2MS3T7B Gmeiner, P; Sommer, J; Mierau, J; Hofner, G TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50282001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50282001&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377783 104123675 CHEMBL34025 ZINC29248050 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728739 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 2.5 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728741 COc1cc(N)c(Cl)cc1C(=O)NC1CCCCN(C1)C(C)C InChI=1S/C17H26ClN3O2/c1-11(2)21-7-5-4-6-12(10-21)20-17(22)13-8-14(18)15(19)9-16(13)23-3/h8-9,11-12H,4-7,10,19H2,1-3H3,(H,20,22) XCUXZSUEQYPQMO-UHFFFAOYSA-N 50069283 4-Amino-5-chloro-N-(1-isopropyl-azepan-3-yl)-2-methoxy-benzamide::CHEMBL351119 D(2) dopamine receptor Rattus norvegicus 87 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371303 103963391 CHEMBL351119 ZINC27710271 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728743 CCNc1cc(OC)c(cc1Cl)C(=O)NC1CCCCN(CC)C1 InChI=1S/C18H28ClN3O2/c1-4-20-16-11-17(24-3)14(10-15(16)19)18(23)21-13-8-6-7-9-22(5-2)12-13/h10-11,13,20H,4-9,12H2,1-3H3,(H,21,23) NXJMOFREJPLYOW-UHFFFAOYSA-N 50069284 5-Chloro-4-ethylamino-N-(1-ethyl-azepan-3-yl)-2-methoxy-benzamide::CHEMBL345220 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069284&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371127 103963392 CHEMBL345220 ZINC27719532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728746 CCN1CCCC[C@H](C1)NC(=O)c1cc(Cl)c(NC)cc1OC InChI=1S/C17H26ClN3O2/c1-4-21-8-6-5-7-12(11-21)20-17(22)13-9-14(18)15(19-2)10-16(13)23-3/h9-10,12,19H,4-8,11H2,1-3H3,(H,20,22)/t12-/m1/s1 QCORICSISJGQIZ-GFCCVEGCSA-N 50366569 CHEMBL1788262 D(2) dopamine receptor Rattus norvegicus 4.5 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54583946 160845671 CHEMBL1788262 ZINC03951826 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728747 CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C16H25ClN4O2/c1-4-21-6-5-20(2)9-11(10-21)19-16(22)12-7-13(17)14(18)8-15(12)23-3/h7-8,11H,4-6,9-10,18H2,1-3H3,(H,19,22) ATMCNNNBGDVDQH-UHFFFAOYSA-N 50069282 4-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-benzamide::CHEMBL346973 D(2) dopamine receptor Rattus norvegicus 127 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11759622 103963390 CHEMBL346973 ZINC36093088 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728748 CCNc1cc(OC)c(cc1Cl)C(=O)NC1CN(C)CCN(CC)C1 InChI=1S/C18H29ClN4O2/c1-5-20-16-10-17(25-4)14(9-15(16)19)18(24)21-13-11-22(3)7-8-23(6-2)12-13/h9-10,13,20H,5-8,11-12H2,1-4H3,(H,21,24) ZXIGYXVBZYGZFG-UHFFFAOYSA-N 50069286 5-Chloro-4-ethylamino-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-benzamide::CHEMBL157784 D(2) dopamine receptor Rattus norvegicus 181 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11014080 103963394 CHEMBL157784 ZINC27703612 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728753 CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(NC)cc1OC InChI=1S/C17H27ClN4O2/c1-5-22-7-6-21(3)10-12(11-22)20-17(23)13-8-14(18)15(19-2)9-16(13)24-4/h8-9,12,19H,5-7,10-11H2,1-4H3,(H,20,23) WKQKHFBNIGVTEQ-UHFFFAOYSA-N 50069288 5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-4-methylamino-benzamide::CHEMBL156188 D(2) dopamine receptor Rattus norvegicus 61 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069288&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11727962 103963396 CHEMBL156188 ZINC00595006 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728754 COc1cc(N)c(Cl)cc1C(=O)NC1CN(C)CCN(C)C1 InChI=1S/C15H23ClN4O2/c1-19-4-5-20(2)9-10(8-19)18-15(21)11-6-12(16)13(17)7-14(11)22-3/h6-7,10H,4-5,8-9,17H2,1-3H3,(H,18,21) MIHPPTZJHZFCPN-UHFFFAOYSA-N 50069290 4-Amino-5-chloro-N-(1,4-dimethyl-[1,4]diazepan-6-yl)-2-methoxy-benzamide::CHEMBL156346 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10336537 103963398 CHEMBL156346 ZINC27707690 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728758 CCCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C17H27ClN4O2/c1-4-5-22-7-6-21(2)10-12(11-22)20-17(23)13-8-14(18)15(19)9-16(13)24-3/h8-9,12H,4-7,10-11,19H2,1-3H3,(H,20,23) UOGOSLXQSCOQQL-UHFFFAOYSA-N 50069289 4-Amino-5-chloro-2-methoxy-N-(1-methyl-4-propyl-[1,4]diazepan-6-yl)-benzamide::CHEMBL345592 D(2) dopamine receptor Rattus norvegicus 218 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11035633 103963397 CHEMBL345592 ZINC36093087 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728759 CCN1CCCCC(C1)NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C16H24ClN3O2/c1-3-20-7-5-4-6-11(10-20)19-16(21)12-8-13(17)14(18)9-15(12)22-2/h8-9,11H,3-7,10,18H2,1-2H3,(H,19,21) UREJLDJPNXRLEF-UHFFFAOYSA-N 50069281 4-Amino-5-chloro-N-(1-ethyl-azepan-3-yl)-2-methoxy-benzamide::CHEMBL347587 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371106 103963389 CHEMBL347587 ZINC27705631 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728762 Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 FELGMEQIXOGIFQ-UHFFFAOYSA-N 85330 CAS_68647::NSC_68647::ONDANSETRON::Ondansetron hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search S87 6W1M 4595 136351430 DB00904 C07325 ZINC00075126 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728766 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C16H25ClN4O2/c1-4-21-6-5-20(2)9-11(10-21)19-16(22)12-7-13(17)14(18)8-15(12)23-3/h7-8,11H,4-6,9-10,18H2,1-3H3,(H,19,22)/t11-/m1/s1 ATMCNNNBGDVDQH-LLVKDONJSA-N 50366568 CHEMBL1788260 D(2) dopamine receptor Rattus norvegicus 87 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11002334 160845670 CHEMBL1788260 ZINC22928209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728767 COc1cc(N)c(Cl)cc1C(=O)NC1CCCCN(C)C1 InChI=1S/C15H22ClN3O2/c1-19-6-4-3-5-10(9-19)18-15(20)11-7-12(16)13(17)8-14(11)21-2/h7-8,10H,3-6,9,17H2,1-2H3,(H,18,20) LRZUMILAVLQNEL-UHFFFAOYSA-N 50069291 4-Amino-5-chloro-2-methoxy-N-(1-methyl-azepan-3-yl)-benzamide::CHEMBL347902 D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069291&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15718473 103963399 CHEMBL347902 ZINC27707372 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728772 CCN1CCCC[C@H](C1)NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C16H24ClN3O2/c1-3-20-7-5-4-6-11(10-20)19-16(21)12-8-13(17)14(18)9-15(12)22-2/h8-9,11H,3-7,10,18H2,1-2H3,(H,19,21)/t11-/m1/s1 UREJLDJPNXRLEF-LLVKDONJSA-N 50366570 CHEMBL1788263 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54583947 160845672 CHEMBL1788263 ZINC27705626 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728773 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 480 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728776 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(NC)cc1OC InChI=1S/C17H27ClN4O2/c1-5-22-7-6-21(3)10-12(11-22)20-17(23)13-8-14(18)15(19-2)9-16(13)24-4/h8-9,12,19H,5-7,10-11H2,1-4H3,(H,20,23)/t12-/m1/s1 WKQKHFBNIGVTEQ-GFCCVEGCSA-N 50070570 5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-4-methylamino-benzamide::CHEMBL40082 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11002742 103964423 CHEMBL40082 ZINC22452401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728779 CCN1CCN(C)C[C@@H](C1)NC(=O)c1cc(Cl)c(NC)cc1OC InChI=1S/C17H27ClN4O2/c1-5-22-7-6-21(3)10-12(11-22)20-17(23)13-8-14(18)15(19-2)9-16(13)24-4/h8-9,12,19H,5-7,10-11H2,1-4H3,(H,20,23)/t12-/m0/s1 WKQKHFBNIGVTEQ-LBPRGKRZSA-N 50366571 CHEMBL1788261 D(2) dopamine receptor Rattus norvegicus 320 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10247591 160845673 CHEMBL1788261 ZINC00595006 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728781 CCN1CCCCC(C1)NC(=O)c1cc(Cl)c(NC)cc1OC InChI=1S/C17H26ClN3O2/c1-4-21-8-6-5-7-12(11-21)20-17(22)13-9-14(18)15(19-2)10-16(13)23-3/h9-10,12,19H,4-8,11H2,1-3H3,(H,20,22) QCORICSISJGQIZ-UHFFFAOYSA-N 50069287 5-Chloro-N-(1-ethyl-azepan-3-yl)-2-methoxy-4-methylamino-benzamide::CHEMBL348517 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9884341 103963395 CHEMBL348517 ZINC13910754 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50728782 CCCN1CCCCC(C1)NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C17H26ClN3O2/c1-3-7-21-8-5-4-6-12(11-21)20-17(22)13-9-14(18)15(19)10-16(13)23-2/h9-10,12H,3-8,11,19H2,1-2H3,(H,20,22) NEHJXJYDQHZELF-UHFFFAOYSA-N 50069285 4-Amino-5-chloro-2-methoxy-N-(1-propyl-azepan-3-yl)-benzamide::CHEMBL436021 D(2) dopamine receptor Rattus norvegicus 57 ChEMBL 10.1016/s0960-894x(98)00078-x 10.7270/Q25Q4WN6 9871571 Hirokawa, Y; Morie, T; Yamazaki, H; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069285&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44371326 103963393 CHEMBL436021 ZINC27706544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722789 CN1CCN(CC1)C1=Cn2cccc2Sc2ccc(F)cc12 InChI=1S/C17H18FN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11-12H,7-10H2,1H3 ZWZRVLJEYRUNHW-UHFFFAOYSA-N 50137972 7-Fluoro-9-(4-methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL366679 D(2) dopamine receptor Rattus norvegicus 8.5 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137972&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9901453 104028110 CHEMBL366679 ZINC28021649 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722794 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722797 Clc1ccc2Sc3cccn3CC(N3CCN(CCN4CCNC4=O)CC3)c2c1 InChI=1S/C21H26ClN5OS/c22-16-3-4-19-17(14-16)18(15-27-6-1-2-20(27)29-19)25-11-8-24(9-12-25)10-13-26-7-5-23-21(26)28/h1-4,6,14,18H,5,7-13,15H2,(H,23,28) NPJJUFNUABZHLO-UHFFFAOYSA-N 50137977 1-{2-[4-(7-Chloro-9,10-dihydro-4-thia-10a-aza-benzo[f]azulen-9-yl)-piperazin-1-yl]-ethyl}-imidazolidin-2-one::CHEMBL367087 D(2) dopamine receptor Rattus norvegicus 125 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137977&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11419055 104028115 CHEMBL367087 ZINC22463657 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722808 CN1CCN(CC1)C1=Cn2cccc2Sc2ccc(Br)cc12 InChI=1S/C17H18BrN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11-12H,7-10H2,1H3 JDXIFXASVQAKDO-UHFFFAOYSA-N 50137975 7-Bromo-9-(4-methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL369367 D(2) dopamine receptor Rattus norvegicus 0.450000 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137975&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11079319 104028113 CHEMBL369367 ZINC13532219 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722810 CN1CCN(CC1)C1=Cn2c(CO)ccc2Sc2ccccc12 InChI=1S/C18H21N3OS/c1-19-8-10-20(11-9-19)16-12-21-14(13-22)6-7-18(21)23-17-5-3-2-4-15(16)17/h2-7,12,22H,8-11,13H2,1H3 GACYTTWULSRQOC-UHFFFAOYSA-N 50137974 CHEMBL367180::[9-(4-Methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulen-1-yl]-methanol D(2) dopamine receptor Rattus norvegicus 854 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137974&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11151583 104028112 CHEMBL367180 ZINC13532228 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50719341 Clc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2cnc3ccccc3c2)CC1 InChI=1S/C23H27ClN4O2S/c24-20-7-5-8-21(17-20)28-14-12-27(13-15-28)11-4-3-10-26-31(29,30)22-16-19-6-1-2-9-23(19)25-18-22/h1-2,5-9,16-18,26H,3-4,10-15H2 WZQQZEZYFURFHH-UHFFFAOYSA-N 50364851 CHEMBL1949963 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1016/j.bmc.2011.12.039 10.7270/Q2HT2PSW 22277589 Zajdel, P; Marciniec, K; Maslankiewicz, A; Satala, G; Duszynska, B; Bojarski, AJ; Partyka, A; Jastrzebska-Wiesek, M; Wrobel, D; Wesolowska, A; Pawlowski, M Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50364851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50364851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57325520 136968913 CHEMBL1949963 ZINC73274863 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50719342 Clc1ccc(cc1)N1CCN(CCCCNS(=O)(=O)c2cnc3ccccc3c2)CC1 InChI=1S/C23H27ClN4O2S/c24-20-7-9-21(10-8-20)28-15-13-27(14-16-28)12-4-3-11-26-31(29,30)22-17-19-5-1-2-6-23(19)25-18-22/h1-2,5-10,17-18,26H,3-4,11-16H2 QCCHEBRTWDZGAB-UHFFFAOYSA-N 50364847 CHEMBL1949967 D(2) dopamine receptor Rattus norvegicus 163 ChEMBL 10.1016/j.bmc.2011.12.039 10.7270/Q2HT2PSW 22277589 Zajdel, P; Marciniec, K; Maslankiewicz, A; Satala, G; Duszynska, B; Bojarski, AJ; Partyka, A; Jastrzebska-Wiesek, M; Wrobel, D; Wesolowska, A; Pawlowski, M Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50364847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50364847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57403839 136968909 CHEMBL1949967 ZINC73278774 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50719343 Clc1ccc(cc1)N1CCN(CCC2CCN(CC2)S(=O)(=O)c2cnc3ccccc3c2)CC1 InChI=1S/C26H31ClN4O2S/c27-23-5-7-24(8-6-23)30-17-15-29(16-18-30)12-9-21-10-13-31(14-11-21)34(32,33)25-19-22-3-1-2-4-26(22)28-20-25/h1-8,19-21H,9-18H2 OGFFWRBVNOYKPL-UHFFFAOYSA-N 50364838 CHEMBL1949976 D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1016/j.bmc.2011.12.039 10.7270/Q2HT2PSW 22277589 Zajdel, P; Marciniec, K; Maslankiewicz, A; Satala, G; Duszynska, B; Bojarski, AJ; Partyka, A; Jastrzebska-Wiesek, M; Wrobel, D; Wesolowska, A; Pawlowski, M Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50364838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50364838&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57396419 136968900 CHEMBL1949976 ZINC73199950 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50719344 Clc1ccc(cc1)N1CCN(CCC2CCN(CC2)S(=O)(=O)c2cncc3ccccc23)CC1 InChI=1S/C26H31ClN4O2S/c27-23-5-7-24(8-6-23)30-17-15-29(16-18-30)12-9-21-10-13-31(14-11-21)34(32,33)26-20-28-19-22-3-1-2-4-25(22)26/h1-8,19-21H,9-18H2 PTCABQYHORAOLY-UHFFFAOYSA-N 50364853 CHEMBL1949977 D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1016/j.bmc.2011.12.039 10.7270/Q2HT2PSW 22277589 Zajdel, P; Marciniec, K; Maslankiewicz, A; Satala, G; Duszynska, B; Bojarski, AJ; Partyka, A; Jastrzebska-Wiesek, M; Wrobel, D; Wesolowska, A; Pawlowski, M Jagiellonian University Medical College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50364853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50364853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57325521 136968915 CHEMBL1949977 ZINC73281002 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722812 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722814 CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 XJGVXQDUIWGIRW-UHFFFAOYSA-N 22871 13-chloro-10-(4-methylpiperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::8-chloro-6-(4-methylpiperazino)benzo[b][1,4]benzoxazepine;succinic acid::CHEMBL831::CL71,563::Cloxazepine::Loxapine D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3964 49846685 50841 CHEMBL831 DB00408 205 C07104 ZINC19796158 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722820 CN1CCN(CC1)C1=Cn2cccc2Sc2ccc(Cl)cc12 InChI=1S/C17H18ClN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11-12H,7-10H2,1H3 HJNMOCAMMZEOBF-UHFFFAOYSA-N 50137981 7-Chloro-9-(4-methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL426763 D(2) dopamine receptor Rattus norvegicus 0.430000 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137981&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9797664 104028119 CHEMBL426763 ZINC13532216 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722822 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Oc2ccccc12 InChI=1S/C18H18ClN3O/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-16(14)23-17-7-6-13(19)12-15(17)20-18/h2-7,12H,8-11H2,1H3 AWHNHDGHHNGACT-UHFFFAOYSA-N 50028980 8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]oxazepine::8-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepine::CHEMBL7828::Isoloxapine D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028980&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10381810 103938110 CHEMBL7828 ZINC13532241 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722828 CN1CCCN(CC1)C1=Cn2cccc2Sc2ccc(Cl)cc12 InChI=1S/C18H20ClN3S/c1-20-7-3-9-21(11-10-20)16-13-22-8-2-4-18(22)23-17-6-5-14(19)12-15(16)17/h2,4-6,8,12-13H,3,7,9-11H2,1H3 FALNVJOEUBWZEU-UHFFFAOYSA-N 50137982 7-Chloro-9-(4-methyl-[1,4]diazepan-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL177455 D(2) dopamine receptor Rattus norvegicus 3.5 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137982&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11727683 104028120 CHEMBL177455 ZINC13532236 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722845 CN1CCN(CC1)[C@@H]1Cn2cccc2Sc2ccc(Cl)cc12 InChI=1S/C17H20ClN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11,15H,7-10,12H2,1H3/t15-/m1/s1 YQXNPUPTPJOJOV-OAHLLOKOSA-N 50137978 (S)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL368324 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137978&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9844271 104028116 CHEMBL368324 ZINC22452134 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722848 CN1CCN(CC1)[C@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m0/s1 XRYLGRGAWQSVQW-KRWDZBQOSA-N 50007568 1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL303313::OCTOCLOTHEPIN-S D(2) dopamine receptor Rattus norvegicus 0.400000 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12765746 103920838 CHEMBL303313 ZINC19368911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722858 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722869 CC(C)OCc1ccc2Sc3ccccc3C(=Cn12)N1CCN(C)CC1 InChI=1S/C21H27N3OS/c1-16(2)25-15-17-8-9-21-24(17)14-19(23-12-10-22(3)11-13-23)18-6-4-5-7-20(18)26-21/h4-9,14,16H,10-13,15H2,1-3H3 ABCRKPVZDDXKEX-UHFFFAOYSA-N 50137985 1-Isopropoxymethyl-9-(4-methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL367875 D(2) dopamine receptor Rattus norvegicus 3824 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137985&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11222444 104028123 CHEMBL367875 ZINC13532231 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722870 CN1CCN(CC1)C1=Cn2c(Sc3ccccc13)ccc2C=O InChI=1S/C18H19N3OS/c1-19-8-10-20(11-9-19)16-12-21-14(13-22)6-7-18(21)23-17-5-3-2-4-15(16)17/h2-7,12-13H,8-11H2,1H3 BNUHYEGPJNDGQR-UHFFFAOYSA-N 50137984 9-(4-Methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene-1-carbaldehyde::CHEMBL362060 D(2) dopamine receptor Rattus norvegicus 1345 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137984&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9945168 104028122 CHEMBL362060 ZINC13532222 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722872 CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m1/s1 XRYLGRGAWQSVQW-QGZVFWFLSA-N 50007567 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL64875::OCTOCLOTHEPIN-R D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603950 103920837 CHEMBL64875 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722873 CN1CCN(CC1)C1=Cc2ccccc2Cc2ccc(Cl)cc12 InChI=1S/C20H21ClN2/c1-22-8-10-23(11-9-22)20-13-16-5-3-2-4-15(16)12-17-6-7-18(21)14-19(17)20/h2-7,13-14H,8-12H2,1H3 SFRWZRKAHVGRFO-UHFFFAOYSA-N 50028601 1-(8-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL7617 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13014692 103937813 CHEMBL7617 ZINC13532247 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722874 CN1CCN(CC1)C1=Cn2c(C)ccc2Sc2ccccc12 InChI=1S/C18H21N3S/c1-14-7-8-18-21(14)13-16(20-11-9-19(2)10-12-20)15-5-3-4-6-17(15)22-18/h3-8,13H,9-12H2,1-2H3 RLPMXJWKLTTXDD-UHFFFAOYSA-N 50137980 1-Methyl-9-(4-methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL176169 D(2) dopamine receptor Rattus norvegicus 126 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137980&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9857902 104028118 CHEMBL176169 ZINC28108687 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722878 CN1CCN(CC1)C1=Cc2cc(Cl)ccc2Cc2ccccc12 InChI=1S/C20H21ClN2/c1-22-8-10-23(11-9-22)20-14-17-13-18(21)7-6-15(17)12-16-4-2-3-5-19(16)20/h2-7,13-14H,8-12H2,1H3 VYHUCPCVCHMNCC-UHFFFAOYSA-N 50028599 1-(2-Chloro-5H-dibenzo[a,d]cyclohepten-10-yl)-4-methyl-piperazine::CHEMBL275696 D(2) dopamine receptor Rattus norvegicus 520 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50028599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50028599&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13014680 103937811 CHEMBL275696 ZINC13532244 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722880 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722889 COCc1ccc2Sc3ccc(Cl)cc3C(Cn12)N1CCN(C)CC1 InChI=1S/C19H24ClN3OS/c1-21-7-9-22(10-8-21)17-12-23-15(13-24-2)4-6-19(23)25-18-5-3-14(20)11-16(17)18/h3-6,11,17H,7-10,12-13H2,1-2H3 AHDOWCJMWQLFRW-UHFFFAOYSA-N 50137979 7-Chloro-1-methoxymethyl-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL175226 D(2) dopamine receptor Rattus norvegicus 1430 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137979&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11406281 104028117 CHEMBL175226 ZINC22930411 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722960 Nc1nc2CC[C@H](Cc2s1)N1CCN(CC1)c1ccccn1 InChI=1S/C16H21N5S/c17-16-19-13-5-4-12(11-14(13)22-16)20-7-9-21(10-8-20)15-3-1-2-6-18-15/h1-3,6,12H,4-5,7-11H2,(H2,17,19)/t12-/m1/s1 FPNSOJRXMGJRFL-GFCCVEGCSA-N 50279866 (R)-6-(4-Pyridin-2-yl-piperazin-1-yl)-4,5,6,7-tetrahydro-benzothiazol-2-ylamine::CHEMBL58265 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1016/S0960-894X(00)80249-8 10.7270/Q2ZC83BV Jaen, JC; Caprathe, BW; Wise, LD; Smith, SJ; Pugsley, TA; Heffner, TG; Meltzer, LT TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15681503 104121570 CHEMBL58265 ZINC29554520 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50722963 CCCN[C@H]1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1 FASDKYOPVNHBLU-ZETCQYMHSA-N 50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570 D(2) dopamine receptor Rattus norvegicus 4700 ChEMBL 10.1016/S0960-894X(00)80249-8 10.7270/Q2ZC83BV Jaen, JC; Caprathe, BW; Wise, LD; Smith, SJ; Pugsley, TA; Heffner, TG; Meltzer, LT TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 119570 104010405 8356 CHEMBL301265 DB00413 ZINC03781664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50724878 COc1cccc2[C@H](CN(C)CCc3ccc4ccoc4c3)CCCc12 InChI=1S/C23H27NO2/c1-24(13-11-17-9-10-18-12-14-26-23(18)15-17)16-19-5-3-7-21-20(19)6-4-8-22(21)25-2/h4,6,8-10,12,14-15,19H,3,5,7,11,13,16H2,1-2H3/t19-/m0/s1 MHPMXTGKTXJIDI-IBGZPJMESA-N 50057128 (2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-amine::A-80426::CHEMBL268258 D(2) dopamine receptor Rattus norvegicus 52 ChEMBL 10.1016/0960-894X(95)00398-D 10.7270/Q2T72HZ0 Meyer, MD; Hancock, AA; Tietje, K; Sippy, kB; Giardina, WJ; Kerwin, JF TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057128&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9928332 103953208 CHEMBL268258 ZINC03810797 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723108 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Rattus norvegicus 1400 ChEMBL 10.1016/S0960-894X(01)80443-1 10.7270/Q28P610P Prucher, H; Gottschlich, R; Haase, A; Stohrer, M; Seyfried, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723110 OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2 ZXUYYZPJUGQHLQ-UHFFFAOYSA-N 50002238 (R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::(S)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-1-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol(BMY-14802)::1-(4-Fluoro-phenyl)-4-[4-(4-fluoro-phenyl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol(BMY-14802)::1-(4-fluorophenyl)-4-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl)butan-1-ol::4-{4-[5-Fluoro-2-(4-fluoro-phenyl)-2H-pyrimidin-1-yl]-piperazin-1-yl}-butan-1-ol::4-{4-[5-Fluoro-2-(4-fluoro-phenyl)-2H-pyrimidin-1-yl]-piperazin-1-yl}-butan-1-ol(BMY 14802)::BMY-14802::CHEMBL60859 D(2) dopamine receptor Rattus norvegicus 4900 ChEMBL 10.1016/S0960-894X(01)80443-1 10.7270/Q28P610P Prucher, H; Gottschlich, R; Haase, A; Stohrer, M; Seyfried, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002238&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 108046 103916544 CHEMBL60859 8 ZINC03995923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50723130 C[C@H]1CN(CCCn2c3ccccc3c3ccccc23)C[C@@H](C)N1 InChI=1S/C21H27N3/c1-16-14-23(15-17(2)22-16)12-7-13-24-20-10-5-3-8-18(20)19-9-4-6-11-21(19)24/h3-6,8-11,16-17,22H,7,12-15H2,1-2H3/t16-,17+ GUDVQJXODNJRIJ-CALCHBBNSA-N 50019742 9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9H-carbazole::9-(3-(3,5-dimethylpiperazin-1-yl)propyl)-9H-carbazole::9-[3-((3R,5R)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-((3R,5S)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-((3S,5R)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole (Rimcazole) (BW234U)::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole(rimcazole)::CHEMBL275707::RIMCAZOLE D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/S0960-894X(01)80443-1 10.7270/Q28P610P Prucher, H; Gottschlich, R; Haase, A; Stohrer, M; Seyfried, C TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019742&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53389 103930665 CHEMBL275707 ZINC22920326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50729741 Fc1ccc(cc1)C(N1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C26H26F2N2/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21/h1-15,26H,16-20H2/b7-4+ SMANXXCATUTDDT-QPJJXVBHSA-N 50017702 1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-((E)-3-phenyl-allyl)-piperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-(3-phenyl-allyl)-piperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-(3-phenyl-allyl)-piperazine(flunarizine)::CHEMBL30008::CHEMBL539027::Flunarizine::NCGC00018102::cid_6365505 D(2) dopamine receptor Rattus norvegicus 228 ChEMBL 10.1016/s0960-894x(99)00516-8 10.7270/Q2D21Z3B 10571163 Annoura, H; Nakanishi, K; Uesugi, M; Fukunaga, A; Miyajima, A; Tamura-Horikawa, Y; Tamura, S Institute for Bio-Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017702&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941361 103928970 CHEMBL539027CHEMBL30008 DB04841 ZINC19360739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50729747 Fc1ccc(Cc2ccc(cc2)C2CCN(C\C=C\c3ccccc3)CC2)cc1 InChI=1S/C27H28FN/c28-27-14-10-24(11-15-27)21-23-8-12-25(13-9-23)26-16-19-29(20-17-26)18-4-7-22-5-2-1-3-6-22/h1-15,26H,16-21H2/b7-4+ JLOMNCFPFBZSKB-QPJJXVBHSA-N 50082323 4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-allyl)-piperidine; hydrochloride::CHEMBL543383 D(2) dopamine receptor Rattus norvegicus 3380 ChEMBL 10.1016/s0960-894x(99)00516-8 10.7270/Q2D21Z3B 10571163 Annoura, H; Nakanishi, K; Uesugi, M; Fukunaga, A; Miyajima, A; Tamura-Horikawa, Y; Tamura, S Institute for Bio-Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9864944 103982126 CHEMBL543383 ZINC13836156 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50729753 OC(COc1ccccc1)CN1CCC(CC1)c1ccc(Cc2ccc(F)cc2)cc1 InChI=1S/C27H30FNO2/c28-25-12-8-22(9-13-25)18-21-6-10-23(11-7-21)24-14-16-29(17-15-24)19-26(30)20-31-27-4-2-1-3-5-27/h1-13,24,26,30H,14-20H2 VWQGDNWLMBJUHU-UHFFFAOYSA-N 50082322 1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-3-phenoxy-propan-2-ol; hydrochloride::CHEMBL543622 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/s0960-894x(99)00516-8 10.7270/Q2D21Z3B 10571163 Annoura, H; Nakanishi, K; Uesugi, M; Fukunaga, A; Miyajima, A; Tamura-Horikawa, Y; Tamura, S Institute for Bio-Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082322&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21349990 103982125 CHEMBL543622 ZINC13836166 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50729756 C(\C=C\c1ccccc1)N1CCC(CC1)c1ccc(Oc2ccccc2)cc1 InChI=1S/C26H27NO/c1-3-8-22(9-4-1)10-7-19-27-20-17-24(18-21-27)23-13-15-26(16-14-23)28-25-11-5-2-6-12-25/h1-16,24H,17-21H2/b10-7+ PUSXGQHPVKPISP-JXMROGBWSA-N 50082320 4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperidine; hydrochloride::CHEMBL545036 D(2) dopamine receptor Rattus norvegicus 2680 ChEMBL 10.1016/s0960-894x(99)00516-8 10.7270/Q2D21Z3B 10571163 Annoura, H; Nakanishi, K; Uesugi, M; Fukunaga, A; Miyajima, A; Tamura-Horikawa, Y; Tamura, S Institute for Bio-Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18412163 103982123 CHEMBL545036 ZINC13836155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50729758 O[C@H](COc1ccccc1)CN1CCC(CC1)c1ccc(Oc2ccccc2)cc1 InChI=1S/C26H29NO3/c28-23(20-29-24-7-3-1-4-8-24)19-27-17-15-22(16-18-27)21-11-13-26(14-12-21)30-25-9-5-2-6-10-25/h1-14,22-23,28H,15-20H2/t23-/m0/s1 FXLWBYZTEVJBSX-QHCPKHFHSA-N 50082324 (S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-yl]-propan-2-ol; hydrochloride::CHEMBL554420 D(2) dopamine receptor Rattus norvegicus 4340 ChEMBL 10.1016/s0960-894x(99)00516-8 10.7270/Q2D21Z3B 10571163 Annoura, H; Nakanishi, K; Uesugi, M; Fukunaga, A; Miyajima, A; Tamura-Horikawa, Y; Tamura, S Institute for Bio-Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332602 103982127 CHEMBL554420 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50725175 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) BVPWJMCABCPUQY-UHFFFAOYSA-N 50132693 4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide(Clebopride)::4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide::CHEMBL325109::Clebopride D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/0960-894X(95)00115-A 10.7270/Q2R78FP7 Langlois, M; Yang, D; Bremont, B; Shen, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2780 104023670 CHEMBL325109 ZINC00608261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50725183 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(C)CC1 InChI=1S/C14H20ClN3O2/c1-18-5-3-9(4-6-18)17-14(19)10-7-11(15)12(16)8-13(10)20-2/h7-9H,3-6,16H2,1-2H3,(H,17,19) IYGMGKYKMGATRC-UHFFFAOYSA-N 50123809 4-Amino-5-chloro-2-methoxy-N-(1-methyl-piperidin-4-yl)-benzamide::CHEMBL164425 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00115-A 10.7270/Q2R78FP7 Langlois, M; Yang, D; Bremont, B; Shen, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44573 104016221 CHEMBL164425 ZINC02000706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50725184 COc1cc(N)c(Cl)cc1C(=O)N[C@@H]1CN2CCC1CC2 InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20)/t13-/m1/s1 FEROPKNOYKURCJ-CYBMUJFWSA-N 50056419 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-((S)-methoxy)-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(S)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxy-benzamide::CHEMBL28992::ZACOPRIDE,R D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00115-A 10.7270/Q2R78FP7 Langlois, M; Yang, D; Bremont, B; Shen, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056419&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604914 103952691 CHEMBL28992 2289 ZINC00003961 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50725186 Nc1cc2OCCOCCN3CCC(CC3)NC(=O)c2cc1Cl InChI=1S/C16H22ClN3O3/c17-13-9-12-15(10-14(13)18)23-8-7-22-6-5-20-3-1-11(2-4-20)19-16(12)21/h9-11H,1-8,18H2,(H,19,21) CEOCEXSTLLSYBV-UHFFFAOYSA-N 50122871 7-Amino-6-chloro-10,13-dioxa-2,16-diaza-tricyclo[14.2.2.0*4,9*]icosa-4,6,8-trien-3-one::CHEMBL116913 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00115-A 10.7270/Q2R78FP7 Langlois, M; Yang, D; Bremont, B; Shen, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11724799 104015489 CHEMBL116913 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50725190 COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC(C1)N2C InChI=1S/C16H22ClN3O2/c1-20-10-3-4-11(20)6-9(5-10)19-16(21)12-7-13(17)14(18)8-15(12)22-2/h7-11H,3-6,18H2,1-2H3,(H,19,21) HTMNINCXKXABOI-UHFFFAOYSA-N 82519 4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)benzamide::BRL 24682::CAS_76272-78-1 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00115-A 10.7270/Q2R78FP7 Langlois, M; Yang, D; Bremont, B; Shen, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9797313 136350489 ZINC13493298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50725191 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 285 ChEMBL 10.1016/0960-894X(95)00115-A 10.7270/Q2R78FP7 Langlois, M; Yang, D; Bremont, B; Shen, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750257 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 36 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750260 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 6 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750280 CCCN1CCO[C@H]2[C@H]1COc1ccc(O)cc21 InChI=1S/C14H19NO3/c1-2-5-15-6-7-17-14-11-8-10(16)3-4-13(11)18-9-12(14)15/h3-4,8,12,14,16H,2,5-7,9H2,1H3/t12-,14-/m1/s1 YOILXOMTHPUMRG-TZMCWYRMSA-N 50010586 (+)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(4aR,10aR)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(Racemic)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(trans)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol (PD 128907)::1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::CHEMBL70565::PD 128,907 D(2) dopamine receptor Rattus norvegicus 3070 ChEMBL 10.1021/jm00119a020 10.7270/Q22R3S82 2903247 Dijkstra, D; Mulder, TB; Rollema, H; Tepper, PG; Van der Weide, J; Horn, AS State University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6O 7CMV 5311346 103923362 CHEMBL70565 ZINC25726114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750281 CCCN1CCO[C@H]2C1COc1c(O)cccc21 InChI=1S/C14H19NO3/c1-2-6-15-7-8-17-13-10-4-3-5-12(16)14(10)18-9-11(13)15/h3-5,11,13,16H,2,6-9H2,1H3/t11?,13-/m1/s1 PQZVZHFVFJNYNL-GLGOKHISSA-N 50020218 1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-8-ol D(2) dopamine receptor Rattus norvegicus 2923 ChEMBL 10.1021/jm00119a020 10.7270/Q22R3S82 2903247 Dijkstra, D; Mulder, TB; Rollema, H; Tepper, PG; Van der Weide, J; Horn, AS State University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020218&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309395 103931132 ZINC26279841 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750282 CCCN1CCO[C@H]2C1CCc1c(O)cccc21 InChI=1S/C15H21NO2/c1-2-8-16-9-10-18-15-12-4-3-5-14(17)11(12)6-7-13(15)16/h3-5,13,15,17H,2,6-10H2,1H3/t13?,15-/m1/s1 NEZSLNYDFZRLJR-AWKYBWMHSA-N 50020219 4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-7-ol D(2) dopamine receptor Rattus norvegicus 75 ChEMBL 10.1021/jm00119a020 10.7270/Q22R3S82 2903247 Dijkstra, D; Mulder, TB; Rollema, H; Tepper, PG; Van der Weide, J; Horn, AS State University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020219&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309198 103931133 ZINC26270718 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750283 CCCN(CCC)C1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3 MDBWEQVKJDMEMK-UHFFFAOYSA-N 50020221 (-)-5-hydroxy-2-(dipropylamino)tetralin::(-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::5-hydroxy-2-(dipropylamino)tetralin::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (DP-5-ADTN)::CHEMBL273273 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm00119a020 10.7270/Q22R3S82 2903247 Dijkstra, D; Mulder, TB; Rollema, H; Tepper, PG; Van der Weide, J; Horn, AS State University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 172267 103931135 CHEMBL273273 128 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750285 CCCN1CCO[C@H]2[C@H]1CCc1ccc(O)cc21 InChI=1S/C15H21NO2/c1-2-7-16-8-9-18-15-13-10-12(17)5-3-11(13)4-6-14(15)16/h3,5,10,14-15,17H,2,4,6-9H2,1H3/t14-,15-/m1/s1 JCSREICEMHWFAY-HUUCEWRRSA-N 50020217 (4aR,10bR)-4-propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::4-Propyl-3,4,4a,5,6,10b-hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol::CHEMBL69271::NAXAGOLIDE HYDROCHLORIDE::PHNO::PHNO,(+) D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm00119a020 10.7270/Q22R3S82 2903247 Dijkstra, D; Mulder, TB; Rollema, H; Tepper, PG; Van der Weide, J; Horn, AS State University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020217&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57533 103931131 CHEMBL69271 ZINC22064446 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750286 CCCN(CCC)C1COc2ccc(O)cc2C1 InChI=1S/C15H23NO2/c1-3-7-16(8-4-2)13-9-12-10-14(17)5-6-15(12)18-11-13/h5-6,10,13,17H,3-4,7-9,11H2,1-2H3 COYBCQFIVNQGKW-UHFFFAOYSA-N 50010587 3-Dipropylamino-chroman-6-ol::CHEMBL69414 D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1021/jm00119a020 10.7270/Q22R3S82 2903247 Dijkstra, D; Mulder, TB; Rollema, H; Tepper, PG; Van der Weide, J; Horn, AS State University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86146 103923363 CHEMBL69414 ZINC05647677 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750287 CCCN(CCC)C1COc2c(O)cccc2C1 InChI=1S/C15H23NO2/c1-3-8-16(9-4-2)13-10-12-6-5-7-14(17)15(12)18-11-13/h5-7,13,17H,3-4,8-11H2,1-2H3 PXSSMALRVSYAFM-UHFFFAOYSA-N 50020220 3-Dipropylamino-chroman-8-ol::CHEMBL38428 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm00119a020 10.7270/Q22R3S82 2903247 Dijkstra, D; Mulder, TB; Rollema, H; Tepper, PG; Van der Weide, J; Horn, AS State University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020220&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86131 103931134 CHEMBL38428 ZINC05647678 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750288 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00119a020 10.7270/Q22R3S82 2903247 Dijkstra, D; Mulder, TB; Rollema, H; Tepper, PG; Van der Weide, J; Horn, AS State University of Groningen http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750184 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753713 CCCN1CCCC(C1)c1csc(N)n1 InChI=1S/C11H19N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h8-9H,2-7H2,1H3,(H2,12,13) GOVJAWLZFVFXRD-UHFFFAOYSA-N 50367938 CHEMBL1203009 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367938&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823148 160847040 CHEMBL1203009 ZINC26937349 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753719 CCCN1CCC=C(C1)c1cnc(N)s1 InChI=1S/C11H17N3S/c1-2-5-14-6-3-4-9(8-14)10-7-13-11(12)15-10/h4,7H,2-3,5-6,8H2,1H3,(H2,12,13) QLUDFKATEBUGML-UHFFFAOYSA-N 50010575 5-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-3H-1lambda*4*-thiazol-2-ylamine::CHEMBL322978 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14510207 103923351 CHEMBL322978 ZINC26938195 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753723 CCCN1CCC=C(C1)c1csc(C)n1 InChI=1S/C12H18N2S/c1-3-6-14-7-4-5-11(8-14)12-9-15-10(2)13-12/h5,9H,3-4,6-8H2,1-2H3 MQLUFBOCYMRCRW-UHFFFAOYSA-N 50367942 CHEMBL1203006 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367942&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14510208 160847044 CHEMBL1203006 ZINC26848298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753725 CCCCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C13H21N3S/c1-2-3-4-7-16-8-5-6-11(9-16)12-10-17-13(14)15-12/h6,10H,2-5,7-9H2,1H3,(H2,14,15) ZQQLUAMRCWINDM-UHFFFAOYSA-N 50367943 CHEMBL1202201 D(2) dopamine receptor Rattus norvegicus 6396 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367943&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823132 160847045 CHEMBL1202201 ZINC26935617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753728 CCCCCCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C15H25N3S/c1-2-3-4-5-6-9-18-10-7-8-13(11-18)14-12-19-15(16)17-14/h8,12H,2-7,9-11H2,1H3,(H2,16,17) PSODDODKEIFPDE-UHFFFAOYSA-N 50367944 CHEMBL1203004 D(2) dopamine receptor Rattus norvegicus 2170 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367944&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823136 160847046 CHEMBL1203004 ZINC36093061 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753732 CN1CCC=C(C1)c1csc(N)n1 InChI=1S/C9H13N3S/c1-12-4-2-3-7(5-12)8-6-13-9(10)11-8/h3,6H,2,4-5H2,1H3,(H2,10,11) NIYQDDWHZSGDEQ-UHFFFAOYSA-N 50367945 CHEMBL1203008 D(2) dopamine receptor Rattus norvegicus 1040 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823127 160847047 CHEMBL1203008 ZINC26938943 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753733 Nc1nc(cs1)C1=CCCN(CCc2ccccc2)C1 InChI=1S/C16H19N3S/c17-16-18-15(12-20-16)14-7-4-9-19(11-14)10-8-13-5-2-1-3-6-13/h1-3,5-7,12H,4,8-11H2,(H2,17,18) VUQQHXCBPFASSP-UHFFFAOYSA-N 50367946 CHEMBL1203001 D(2) dopamine receptor Rattus norvegicus 911 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823140 160847048 CHEMBL1203001 ZINC26847412 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753734 CCCCCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C14H23N3S/c1-2-3-4-5-8-17-9-6-7-12(10-17)13-11-18-14(15)16-13/h7,11H,2-6,8-10H2,1H3,(H2,15,16) YIMBWRIQKZKNDQ-UHFFFAOYSA-N 50367941 CHEMBL1203003 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823134 160847043 CHEMBL1203003 ZINC26846335 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753744 CCCCN1CCC=C(C1)c1csc(NC)n1 InChI=1S/C13H21N3S/c1-3-4-7-16-8-5-6-11(9-16)12-10-17-13(14-2)15-12/h6,10H,3-5,7-9H2,1-2H3,(H,14,15) KKGUCVMOJNBBFW-UHFFFAOYSA-N 50367947 CHEMBL1203005 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14510201 160847049 CHEMBL1203005 ZINC26936915 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753746 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753747 CCCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C12H19N3S/c1-2-3-6-15-7-4-5-10(8-15)11-9-16-12(13)14-11/h5,9H,2-4,6-8H2,1H3,(H2,13,14) DSEWXIWVTCTEJG-UHFFFAOYSA-N 50367940 CHEMBL1203007 D(2) dopamine receptor Rattus norvegicus 2120 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367940&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823130 160847042 CHEMBL1203007 ZINC26843782 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50759836 CCN1CCCC1c1ccc([nH]1)-c1cc(ccc1OC)S(=O)(=O)CC InChI=1S/C19H26N2O3S/c1-4-21-12-6-7-18(21)17-10-9-16(20-17)15-13-14(25(22,23)5-2)8-11-19(15)24-3/h8-11,13,18,20H,4-7,12H2,1-3H3 PWMDANRQWZFAPB-UHFFFAOYSA-N 50005117 (racemic)5'-(5-Ethanesulfonyl-2-methoxy-phenyl)-1-ethyl-2,3,4,5-tetrahydro-1H,1'H-[2,2']bipyrrolyl::5'-(5-Ethanesulfonyl-2-methoxy-phenyl)-1-ethyl-2,3,4,5-tetrahydro-1H,1'H-[2,2']bipyrrolyl::CHEMBL277631 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005117&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 443374 103918663 CHEMBL277631 C11709 ZINC04102179 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50759848 CCN1CCC[C@@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m1/s1 WAOQONBSWFLFPE-SECBINFHSA-N 50005121 (R)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::CHEMBL308129 D(2) dopamine receptor Rattus norvegicus 2920 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55216 103918667 CHEMBL308129 959 ZINC00002021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762159 Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ncc(Cl)cn1 InChI=1S/C18H20ClFN4O/c19-15-12-21-18(22-13-15)24-10-8-23(9-11-24)7-1-2-17(25)14-3-5-16(20)6-4-14/h3-6,12-13H,1-2,7-11H2 VIKBJCYXHQEQEN-UHFFFAOYSA-N 50002335 4-[4-(5-Chloro-pyrimidin-2-yl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one::CHEMBL137870 D(2) dopamine receptor Rattus norvegicus 817 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002335&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10316614 103916641 CHEMBL137870 ZINC13730846 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762162 Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ncccn1 InChI=1S/C18H21FN4O/c19-16-6-4-15(5-7-16)17(24)3-1-10-22-11-13-23(14-12-22)18-20-8-2-9-21-18/h2,4-9H,1,3,10-14H2 WEVJMQOBCRCIPF-UHFFFAOYSA-N 50002334 1-(4-Fluoro-phenyl)-4-(4-pyrimidin-2-yl-piperazin-1-yl)-butan-1-one::4-[4-(2-Pyrimidine)piperazin-1-yl]-1-(4-fluorophenyl)-butan-1-one::CHEMBL140872 D(2) dopamine receptor Rattus norvegicus 679 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10065083 103916640 CHEMBL140872 ZINC13730842 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762164 Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ncc(Br)cn1 InChI=1S/C18H20BrFN4O/c19-15-12-21-18(22-13-15)24-10-8-23(9-11-24)7-1-2-17(25)14-3-5-16(20)6-4-14/h3-6,12-13H,1-2,7-11H2 SSIBROUSXPGCKR-UHFFFAOYSA-N 50002320 4-[4-(5-Bromo-pyrimidin-2-yl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one::CHEMBL141922 D(2) dopamine receptor Rattus norvegicus 2190 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10001423 103916626 CHEMBL141922 ZINC13730849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762170 Fc1ccc(\C=C(/CCN2CCN(CC2)c2ncc(F)cn2)c2ccc(F)cc2)cc1 InChI=1S/C24H23F3N4/c25-21-5-1-18(2-6-21)15-20(19-3-7-22(26)8-4-19)9-10-30-11-13-31(14-12-30)24-28-16-23(27)17-29-24/h1-8,15-17H,9-14H2/b20-15+ LHHHTHPGNCCTBY-HMMYKYKNSA-N 50002332 2-{4-[3,4-Bis-(4-fluoro-phenyl)-but-3-enyl]-piperazin-1-yl}-5-fluoro-pyrimidine::CHEMBL344577 D(2) dopamine receptor Rattus norvegicus 8800 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002332&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44359979 103916638 CHEMBL344577 ZINC27522730 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762173 CC(O)(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C19H24F2N4O/c1-19(26,15-3-5-16(20)6-4-15)7-2-8-24-9-11-25(12-10-24)18-22-13-17(21)14-23-18/h3-6,13-14,26H,2,7-12H2,1H3 INVDAXJKYDQCMS-UHFFFAOYSA-N 50002336 2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-pentan-2-ol::CHEMBL141912 D(2) dopamine receptor Rattus norvegicus 2120 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10021536 103916642 CHEMBL141912 ZINC13730903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762174 OC(CCCN1CCN(CC1)c1ncccn1)c1ccc(F)cc1 InChI=1S/C18H23FN4O/c19-16-6-4-15(5-7-16)17(24)3-1-10-22-11-13-23(14-12-22)18-20-8-2-9-21-18/h2,4-9,17,24H,1,3,10-14H2 ZTPBJWUQRZTCOT-UHFFFAOYSA-N 50002337 1-(4-Fluoro-phenyl)-4-(4-pyrimidin-2-yl-piperazin-1-yl)-butan-1-ol::CHEMBL335348 D(2) dopamine receptor Rattus norvegicus 1380 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10426775 103916643 CHEMBL335348 ZINC13730861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762175 NC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C18H23F2N5/c19-15-5-3-14(4-6-15)17(21)2-1-7-24-8-10-25(11-9-24)18-22-12-16(20)13-23-18/h3-6,12-13,17H,1-2,7-11,21H2 YTEBHKVWLVDMRI-UHFFFAOYSA-N 50002319 1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butylamine::CHEMBL137967 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9974985 103916625 CHEMBL137967 ZINC13730939 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762178 CSc1nc(ncc1F)N1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C19H22F2N4OS/c1-27-18-16(21)13-22-19(23-18)25-11-9-24(10-12-25)8-2-3-17(26)14-4-6-15(20)7-5-14/h4-7,13H,2-3,8-12H2,1H3 TVZQYADMEATGII-UHFFFAOYSA-N 50002328 4-[4-(5-Fluoro-4-methylsulfanyl-pyrimidin-2-yl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one::CHEMBL141455 D(2) dopamine receptor Rattus norvegicus 396 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002328&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977829 103916634 CHEMBL141455 ZINC13730852 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762181 OC(CCCN1CCN(CC1)c1ncc(Br)cn1)c1ccc(F)cc1 InChI=1S/C18H22BrFN4O/c19-15-12-21-18(22-13-15)24-10-8-23(9-11-24)7-1-2-17(25)14-3-5-16(20)6-4-14/h3-6,12-13,17,25H,1-2,7-11H2 UASRUXDOOPQISL-UHFFFAOYSA-N 50002323 4-[4-(5-Bromo-pyrimidin-2-yl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-ol::CHEMBL141670 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10476595 103916629 CHEMBL141670 ZINC13730873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762183 COc1nc(ncc1F)N1CCN(CCCC(O)c2ccc(F)cc2)CC1 InChI=1S/C19H24F2N4O2/c1-27-18-16(21)13-22-19(23-18)25-11-9-24(10-12-25)8-2-3-17(26)14-4-6-15(20)7-5-14/h4-7,13,17,26H,2-3,8-12H2,1H3 LTCULVKPMWAHBA-UHFFFAOYSA-N 50002331 4-[4-(5-Fluoro-4-methoxy-pyrimidin-2-yl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-ol::CHEMBL141854 D(2) dopamine receptor Rattus norvegicus 3940 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002331&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10474783 103916637 CHEMBL141854 ZINC13730891 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762186 O[C@H](CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2/t17-/m1/s1 ZXUYYZPJUGQHLQ-QGZVFWFLSA-N 50036737 (R)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::CHEMBL129768 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604868 103944378 CHEMBL129768 ZINC03995923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762187 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762189 OC(CCCN1CCN(CC1)c1ncc(F)c(=O)[nH]1)c1ccc(F)cc1 InChI=1S/C18H22F2N4O2/c19-14-5-3-13(4-6-14)16(25)2-1-7-23-8-10-24(11-9-23)18-21-12-15(20)17(26)22-18/h3-6,12,16,25H,1-2,7-11H2,(H,21,22,26) PEPKQWOGJXYSSI-UHFFFAOYSA-N 50002324 5-Fluoro-2-{4-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperazin-1-yl}-pyrimidin-4-ol::CHEMBL140833 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9976005 103916630 CHEMBL140833 ZINC13730885 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762190 OC(CCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C17H20F2N4O/c18-14-3-1-13(2-4-14)16(24)5-6-22-7-9-23(10-8-22)17-20-11-15(19)12-21-17/h1-4,11-12,16,24H,5-10H2 GJHQJZCASPURFX-UHFFFAOYSA-N 50002340 1-(4-Fluoro-phenyl)-3-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-propan-1-ol::CHEMBL140712 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10404634 103916646 CHEMBL140712 ZINC13730897 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762191 Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1ncc(F)cn1 InChI=1S/C18H20F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13H,1-2,7-11H2 SFCGNFIBDYIEJN-UHFFFAOYSA-N 50002339 1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-one::CHEMBL140656 D(2) dopamine receptor Rattus norvegicus 494 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131695 103916645 CHEMBL140656 ZINC53218751 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762192 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 440 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762195 OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2 ZXUYYZPJUGQHLQ-UHFFFAOYSA-N 50002238 (R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::(S)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-1-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol(BMY-14802)::1-(4-Fluoro-phenyl)-4-[4-(4-fluoro-phenyl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol(BMY-14802)::1-(4-fluorophenyl)-4-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl)butan-1-ol::4-{4-[5-Fluoro-2-(4-fluoro-phenyl)-2H-pyrimidin-1-yl]-piperazin-1-yl}-butan-1-ol::4-{4-[5-Fluoro-2-(4-fluoro-phenyl)-2H-pyrimidin-1-yl]-piperazin-1-yl}-butan-1-ol(BMY 14802)::BMY-14802::CHEMBL60859 D(2) dopamine receptor Rattus norvegicus 6430 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002238&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 108046 103916544 CHEMBL60859 8 ZINC03995923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762196 CSc1nc(ncc1F)N1CCN(CCCC(O)c2ccc(F)cc2)CC1 InChI=1S/C19H24F2N4OS/c1-27-18-16(21)13-22-19(23-18)25-11-9-24(10-12-25)8-2-3-17(26)14-4-6-15(20)7-5-14/h4-7,13,17,26H,2-3,8-12H2,1H3 UOPZCHLWGQQVGX-UHFFFAOYSA-N 50002322 4-[4-(5-Fluoro-4-methylsulfanyl-pyrimidin-2-yl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-ol::CHEMBL140650 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002322&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10363230 103916628 CHEMBL140650 ZINC13730879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746420 CCN1CCC[C@H]1CNC(=O)c1c(O)c(F)ccc1OC InChI=1S/C15H21FN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 MLQJUWHDLUCERD-JTQLQIEISA-N 50026554 CHEMBL276977::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-fluoro-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 362 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026554&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493798 103936194 CHEMBL276977 ZINC28261157 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746421 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Rattus norvegicus 1570 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746422 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC(C)=O InChI=1S/C17H23BrN2O4/c1-4-20-9-5-6-12(20)10-19-17(22)15-14(23-3)8-7-13(18)16(15)24-11(2)21/h7-8,12H,4-6,9-10H2,1-3H3,(H,19,22)/t12-/m0/s1 JHILJNVWNUBBMS-LBPRGKRZSA-N 50026556 Acetic acid 6-bromo-2-[(1-ethyl-pyrrolidin-2-ylmethyl)-carbamoyl]-3-methoxy-phenyl ester::CHEMBL282681 D(2) dopamine receptor Rattus norvegicus 3500 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44458590 103936196 CHEMBL282681 ZINC28258784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746423 CCN1CCC[C@H]1CNC(=O)c1c(O)cccc1OC InChI=1S/C15H22N2O3/c1-3-17-9-5-6-11(17)10-16-15(19)14-12(18)7-4-8-13(14)20-2/h4,7-8,11,18H,3,5-6,9-10H2,1-2H3,(H,16,19)/t11-/m0/s1 MVWKVVFFVMXULU-NSHDSACASA-N 50012964 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::CHEMBL8945::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (BZM) D(2) dopamine receptor Rattus norvegicus 315 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10956830 103925212 CHEMBL8945 ZINC05851787 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746424 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 233 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746425 CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(CC)c1OC InChI=1S/C17H26N2O3/c1-4-12-8-9-14(20)15(16(12)22-3)17(21)18-11-13-7-6-10-19(13)5-2/h8-9,13,20H,4-7,10-11H2,1-3H3,(H,18,21)/t13-/m0/s1 OQXGPPSRXAKOOA-ZDUSSCGKSA-N 50026557 3-Ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::CHEMBL431490 D(2) dopamine receptor Rattus norvegicus 123 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493820 103936197 CHEMBL431490 ZINC28260582 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746426 CCCN1CCC[C@H]1CNC(=O)c1c(O)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-3-8-19-9-4-5-11(19)10-18-16(21)14-13(20)7-6-12(17)15(14)22-2/h6-7,11,20H,3-5,8-10H2,1-2H3,(H,18,21)/t11-/m0/s1 SCMOLCMJRRMFEV-NSHDSACASA-N 50026558 3-Bromo-6-hydroxy-2-methoxy-N-(1-propyl-pyrrolidin-2-ylmethyl)-benzamide::CHEMBL280953 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493832 103936198 CHEMBL280953 ZINC28260528 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746427 CCOc1c(Br)ccc(OC)c1C(=O)NC[C@@H]1CCCN1CC InChI=1S/C17H25BrN2O3/c1-4-20-10-6-7-12(20)11-19-17(21)15-14(22-3)9-8-13(18)16(15)23-5-2/h8-9,12H,4-7,10-11H2,1-3H3,(H,19,21)/t12-/m0/s1 UANCYESJBBDKLC-LBPRGKRZSA-N 50026559 3-Bromo-2-ethoxy-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-methoxy-benzamide::CHEMBL282463 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44458636 103936199 CHEMBL282463 ZINC28260576 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746428 CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(Br)c1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(19)7-6-11(16)14(13)21-2/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 QRMZHEDLUQMLGK-JTQLQIEISA-N 50026561 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::CHEMBL23519 D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493823 103936201 CHEMBL23519 ZINC05851784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746429 CCCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C16H23BrN2O3/c1-3-8-19-9-4-5-11(19)10-18-16(21)14-13(22-2)7-6-12(17)15(14)20/h6-7,11,20H,3-5,8-10H2,1-2H3,(H,18,21)/t11-/m0/s1 HEKGCOHQFZQHCJ-NSHDSACASA-N 50026560 3-Bromo-2-hydroxy-6-methoxy-N-(1-propyl-pyrrolidin-2-ylmethyl)-benzamide::CHEMBL23437 D(2) dopamine receptor Rattus norvegicus 6.3 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493829 103936200 CHEMBL23437 ZINC28260533 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746430 CCN1CCC[C@H]1CNC(=O)c1c(O)c(C)ccc1OC InChI=1S/C16H24N2O3/c1-4-18-9-5-6-12(18)10-17-16(20)14-13(21-3)8-7-11(2)15(14)19/h7-8,12,19H,4-6,9-10H2,1-3H3,(H,17,20)/t12-/m0/s1 UMEBCICPUODHSU-LBPRGKRZSA-N 50026562 CHEMBL23228::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-3-methyl-benzamide D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493806 103936202 CHEMBL23228 ZINC28259744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746431 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746432 CCN1CCC[C@H]1CNC(=O)c1c(O)c(ccc1OC)[N+]([O-])=O InChI=1S/C15H21N3O5/c1-3-17-8-4-5-10(17)9-16-15(20)13-12(23-2)7-6-11(14(13)19)18(21)22/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,16,20)/t10-/m0/s1 CQEIHZMCJGGOEX-JTQLQIEISA-N 50026564 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::CHEMBL279982::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-3-nitro-benzamide D(2) dopamine receptor Rattus norvegicus 3020 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493803 103936204 CHEMBL279982 ZINC28256944 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746433 CCCc1ccc(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1O InChI=1S/C18H28N2O3/c1-4-7-13-9-10-15(23-3)16(17(13)21)18(22)19-12-14-8-6-11-20(14)5-2/h9-10,14,21H,4-8,11-12H2,1-3H3,(H,19,22)/t14-/m0/s1 GXLRFNYVOBFUES-AWEZNQCLSA-N 50026563 CHEMBL22472::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-3-propyl-benzamide D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493811 103936203 CHEMBL22472 ZINC28257421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746434 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(I)c1OC InChI=1S/C16H23IN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 JJYGMNQCYKVCSO-NSHDSACASA-N 50026568 CHEMBL23464::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-iodo-2,6-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 2790 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493784 103936208 CHEMBL23464 ZINC28260993 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746435 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(CC)c1OC InChI=1S/C18H28N2O3/c1-5-13-9-10-15(22-3)16(17(13)23-4)18(21)19-12-14-8-7-11-20(14)6-2/h9-10,14H,5-8,11-12H2,1-4H3,(H,19,21)/t14-/m0/s1 GGEDSWLSSJZGKV-AWEZNQCLSA-N 50026565 3-Ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::CHEMBL282925 D(2) dopamine receptor Rattus norvegicus 921 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493791 103936205 CHEMBL282925 ZINC28261146 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746436 CCN1CCC[C@H]1CNC(=O)c1c(OC)cccc1OC InChI=1S/C16H24N2O3/c1-4-18-10-6-7-12(18)11-17-16(19)15-13(20-2)8-5-9-14(15)21-3/h5,8-9,12H,4,6-7,10-11H2,1-3H3,(H,17,19)/t12-/m0/s1 XHDCLFMAXFUNGX-LBPRGKRZSA-N 50026566 CHEMBL282024::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 15300 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15565706 103936206 CHEMBL282024 ZINC28259401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746437 CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(Cl)c1OC InChI=1S/C15H21ClN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(19)7-6-11(16)14(13)21-2/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 IBUGWYFNHKGWRI-JTQLQIEISA-N 50026567 3-Chloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::CHEMBL278767 D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493822 103936207 CHEMBL278767 ZINC28256963 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746438 CCCCc1ccc(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1O InChI=1S/C19H30N2O3/c1-4-6-8-14-10-11-16(24-3)17(18(14)22)19(23)20-13-15-9-7-12-21(15)5-2/h10-11,15,22H,4-9,12-13H2,1-3H3,(H,20,23)/t15-/m0/s1 HECDGIYPWMEZGS-HNNXBMFYSA-N 50026569 3-Butyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::CHEMBL268555 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493814 103936209 CHEMBL268555 ZINC28256938 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746439 CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)ccc1OC InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 CANPFCFJURGKAX-JTQLQIEISA-N 50012961 (-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::CHEMBL267723::N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide (IBZM)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide( (S)-(-)IBZM) D(2) dopamine receptor Rattus norvegicus 3.40 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 107995 103925209 CHEMBL267723 ZINC03786360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746441 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)ccc1OC InChI=1S/C17H26N2O3/c1-4-12-8-9-14(22-3)15(16(12)20)17(21)18-11-13-7-6-10-19(13)5-2/h8-9,13,20H,4-7,10-11H2,1-3H3,(H,18,21)/t13-/m0/s1 YMTZSXGHAFKWEQ-ZDUSSCGKSA-N 50026059 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 37843::CHEMBL23403 D(2) dopamine receptor Rattus norvegicus 4.7 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026059&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55217 103935793 CHEMBL23403 ZINC05688578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746443 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)ccc1OC InChI=1S/C15H21ClN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 GNUARZZEUPYJBU-JTQLQIEISA-N 50026570 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::CHEMBL23845 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493817 103936210 CHEMBL23845 ZINC28260609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746444 CCCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C17H25BrN2O3/c1-4-9-20-10-5-6-12(20)11-19-17(21)15-14(22-2)8-7-13(18)16(15)23-3/h7-8,12H,4-6,9-11H2,1-3H3,(H,19,21)/t12-/m0/s1 PPAUVJZNYKISEQ-LBPRGKRZSA-N 50026571 3-Bromo-2,6-dimethoxy-N-(1-propyl-pyrrolidin-2-ylmethyl)-benzamide::CHEMBL278560 D(2) dopamine receptor Rattus norvegicus 987 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13493826 103936211 CHEMBL278560 ZINC28256887 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746445 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Cl)c1OC InChI=1S/C16H23ClN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 CQFIGXQADSIOPJ-NSHDSACASA-N 50026572 3-Chloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::CHEMBL23932 D(2) dopamine receptor Rattus norvegicus 3190 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54956 103936212 CHEMBL23932 ZINC05650381 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753846 Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1 XEXUKNQDDPKEIF-OAHLLOKOSA-N 50007423 (R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrobromide::CHEMBL318111::CHEMBL542493::cid_11957524 D(2) dopamine receptor Rattus norvegicus 0.240000 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007423&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 838674 103920698 CHEMBL318111CHEMBL542493 ZINC00366660 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753850 OCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C18H19NO3/c20-9-8-19-7-6-11-2-1-3-13-16(11)14(19)10-12-4-5-15(21)18(22)17(12)13/h1-5,14,20-22H,6-10H2/t14-/m1/s1 SWOYTIGXQORDEW-CQSZACIVSA-N 50012987 6-(2-Hydroxy-ethyl)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL553060 D(2) dopamine receptor Rattus norvegicus 1460 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10017524 103925227 CHEMBL553060 ZINC13509357 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753852 CCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C18H19NO2/c1-2-19-9-8-11-4-3-5-13-16(11)14(19)10-12-6-7-15(20)18(21)17(12)13/h3-7,14,20-21H,2,8-10H2,1H3/t14-/m1/s1 YPNFSVPDCPRGIG-CQSZACIVSA-N 50012990 6-Ethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL544618 D(2) dopamine receptor Rattus norvegicus 0.220000 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012990&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3032727 103925230 CHEMBL544618 ZINC27518486 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753859 Oc1ccc2C[C@H]3N(CC(F)(F)F)CCc4cccc(c34)-c2c1O InChI=1S/C18H16F3NO2/c19-18(20,21)9-22-7-6-10-2-1-3-12-15(10)13(22)8-11-4-5-14(23)17(24)16(11)12/h1-5,13,23-24H,6-9H2/t13-/m1/s1 RBPGCCWXYDPSBT-CYBMUJFWSA-N 50012995 6-(2,2,2-Trifluoro-ethyl)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL555049 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14488821 103925235 CHEMBL555049 ZINC27517448 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753862 Oc1ccc2C[C@H]3N(CC(F)(F)C(F)(F)F)CCc4cccc(c34)-c2c1O InChI=1S/C19H16F5NO2/c20-18(21,19(22,23)24)9-25-7-6-10-2-1-3-12-15(10)13(25)8-11-4-5-14(26)17(27)16(11)12/h1-5,13,26-27H,6-9H2/t13-/m1/s1 JDUJZJYLYXZGTG-CYBMUJFWSA-N 50012988 6-(2,2,3,3,3-Pentafluoro-propyl)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL558417 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012988&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14488829 103925228 CHEMBL558417 ZINC27440152 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753865 Oc1ccc2C[C@H]3N(CC4CC4)CCc4cccc(c34)-c2c1O InChI=1S/C20H21NO2/c22-17-7-6-14-10-16-18-13(8-9-21(16)11-12-4-5-12)2-1-3-15(18)19(14)20(17)23/h1-3,6-7,12,16,22-23H,4-5,8-11H2/t16-/m1/s1 OXQZCFBTWSWVNN-MRXNPFEDSA-N 50012991 6-Cyclopropylmethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL541867 D(2) dopamine receptor Rattus norvegicus 0.430000 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012991&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033276 103925231 CHEMBL541867 ZINC02000209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753866 CC(C)CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H23NO2/c1-12(2)11-21-9-8-13-4-3-5-15-18(13)16(21)10-14-6-7-17(22)20(23)19(14)15/h3-7,12,16,22-23H,8-11H2,1-2H3/t16-/m1/s1 NVFJFPLZIORLGC-MRXNPFEDSA-N 50012993 6-Isobutyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL540577 D(2) dopamine receptor Rattus norvegicus 490 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14193426 103925233 CHEMBL540577 ZINC27518476 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753869 CC(C)N1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-11(2)20-9-8-12-4-3-5-14-17(12)15(20)10-13-6-7-16(21)19(22)18(13)14/h3-7,11,15,21-22H,8-10H2,1-2H3/t15-/m1/s1 ROPJFLMUAFHJGW-OAHLLOKOSA-N 50012992 6-Isopropyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL555279 D(2) dopamine receptor Rattus norvegicus 895 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012992&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14193423 103925232 CHEMBL555279 ZINC27518541 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753870 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753873 Oc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O InChI=1S/C16H15NO2/c18-13-5-4-10-8-12-14-9(6-7-17-12)2-1-3-11(14)15(10)16(13)19/h1-5,12,17-19H,6-8H2/t12-/m1/s1 MHPQCGZBAVXCGA-GFCCVEGCSA-N 50012989 5,6,6a,7-Tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL541862 D(2) dopamine receptor Rattus norvegicus 1190 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012989&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 30133 103925229 CHEMBL541862 ZINC03874848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753878 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50012994 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrochloride::CHEMBL538542::NPA,(+)::SKF-76783::cid_11957529 D(2) dopamine receptor Rattus norvegicus 0.800000 ChEMBL 10.1021/jm00163a007 10.7270/Q2183732 2136919 Gao, YG; Ram, VJ; Campbell, A; Kula, NS; Baldessarini, RJ; Neumeyer, JL Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103925234 CHEMBL538542 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50740971 COc1ccc2[nH]cc(C3=CCN(CCC4OCCc5cc(ccc45)C(N)=O)CC3)c2c1 InChI=1S/C26H29N3O3/c1-31-20-3-5-24-22(15-20)23(16-28-24)17-6-10-29(11-7-17)12-8-25-21-4-2-19(26(27)30)14-18(21)9-13-32-25/h2-6,14-16,25,28H,7-13H2,1H3,(H2,27,30) SPGZQVBCFBJOGF-UHFFFAOYSA-N 50145332 1-{2-[4-(5-Methoxy-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL84171 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145332&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461306 104034173 CHEMBL84171 ZINC26498914 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50740980 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3c[nH]c4ccc(F)cc34)OCCc2c1 InChI=1S/C25H26FN3O2/c26-19-2-4-23-21(14-19)22(15-28-23)16-5-9-29(10-6-16)11-7-24-20-3-1-18(25(27)30)13-17(20)8-12-31-24/h1-5,13-15,24,28H,6-12H2,(H2,27,30) ILKQRUVBTOCMJS-UHFFFAOYSA-N 50145341 1-{2-[4-(5-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL79561 D(2) dopamine receptor Rattus norvegicus 2.1 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461293 104034182 CHEMBL79561 ZINC26497345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746565 CCCN1CCC[C@H](C1)c1ccc(O)c(O)c1 InChI=1S/C14H21NO2/c1-2-7-15-8-3-4-12(10-15)11-5-6-13(16)14(17)9-11/h5-6,9,12,16-17H,2-4,7-8,10H2,1H3/t12-/m1/s1 JBPMHBLMULBWFU-GFCCVEGCSA-N 50367280 CHEMBL1907814 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00160a016 10.7270/Q2ZC83F6 3761308 Rollema, H; Mastebroek, D; Wikstrom, H; Svensson, K; Carlsson, A; Sundell, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53946795 160846382 CHEMBL1907814 ZINC05833832 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746566 CCCN1CCC[C@@H](C1)c1ccc(O)c(O)c1 InChI=1S/C14H21NO2/c1-2-7-15-8-3-4-12(10-15)11-5-6-13(16)14(17)9-11/h5-6,9,12,16-17H,2-4,7-8,10H2,1H3/t12-/m0/s1 JBPMHBLMULBWFU-LBPRGKRZSA-N 50367281 CHEMBL1907969 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm00160a016 10.7270/Q2ZC83F6 3761308 Rollema, H; Mastebroek, D; Wikstrom, H; Svensson, K; Carlsson, A; Sundell, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53946796 160846383 CHEMBL1907969 ZINC05833744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746568 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm00160a016 10.7270/Q2ZC83F6 3761308 Rollema, H; Mastebroek, D; Wikstrom, H; Svensson, K; Carlsson, A; Sundell, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746569 CCCN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m0/s1 HTSNFXAICLXZMA-ZDUSSCGKSA-N 50010618 (+)-3-(1-Propyl-piperidin-3-yl)-phenol::3-((R)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(-)::CHEMBL7393::cid_202478 D(2) dopamine receptor Rattus norvegicus 189 ChEMBL 10.1021/jm00160a016 10.7270/Q2ZC83F6 3761308 Rollema, H; Mastebroek, D; Wikstrom, H; Svensson, K; Carlsson, A; Sundell, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 202478 103923392 CHEMBL7393 ZINC00000393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50746571 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm00160a016 10.7270/Q2ZC83F6 3761308 Rollema, H; Mastebroek, D; Wikstrom, H; Svensson, K; Carlsson, A; Sundell, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756080 CCCN(CCc1ccccc1)CCc1ccc(O)c(F)c1 InChI=1S/C19H24FNO/c1-2-12-21(13-10-16-6-4-3-5-7-16)14-11-17-8-9-19(22)18(20)15-17/h3-9,15,22H,2,10-14H2,1H3 NPECQGDFUHBZFR-UHFFFAOYSA-N 50010729 2-Fluoro-4-[2-(phenethyl-propyl-amino)-ethyl]-phenol; hydrobromide::CHEMBL538012 D(2) dopamine receptor Rattus norvegicus 580 ChEMBL 10.1021/jm00171a014 10.7270/Q29G5NFT 1975274 Claudi, F; Cardellini, M; Cingolani, GM; Piergentili, A; Peruzzi, G; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010729&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14901835 103923475 CHEMBL538012 ZINC26480703 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756081 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 70 ChEMBL 10.1021/jm00171a014 10.7270/Q29G5NFT 1975274 Claudi, F; Cardellini, M; Cingolani, GM; Piergentili, A; Peruzzi, G; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756083 CCCN(CCc1ccccc1)CCc1ccc(F)c(O)c1 InChI=1S/C19H24FNO/c1-2-12-21(13-10-16-6-4-3-5-7-16)14-11-17-8-9-18(20)19(22)15-17/h3-9,15,22H,2,10-14H2,1H3 JBNSAJXDKKTLOT-UHFFFAOYSA-N 50010731 2-Fluoro-5-[2-(phenethyl-propyl-amino)-ethyl]-phenol; hydrobromide::CHEMBL543838 D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm00171a014 10.7270/Q29G5NFT 1975274 Claudi, F; Cardellini, M; Cingolani, GM; Piergentili, A; Peruzzi, G; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010731&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14901831 103923477 CHEMBL543838 ZINC26489837 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756084 CCN(CCc1ccccc1)CCc1ccc(F)c(O)c1 InChI=1S/C18H22FNO/c1-2-20(12-10-15-6-4-3-5-7-15)13-11-16-8-9-17(19)18(21)14-16/h3-9,14,21H,2,10-13H2,1H3 FHPPQCKJDLXMNZ-UHFFFAOYSA-N 50010733 5-[2-(Ethyl-phenethyl-amino)-ethyl]-2-fluoro-phenol; hydrobromide::CHEMBL540546 D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1021/jm00171a014 10.7270/Q29G5NFT 1975274 Claudi, F; Cardellini, M; Cingolani, GM; Piergentili, A; Peruzzi, G; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010733&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14901825 103923479 CHEMBL540546 ZINC26480707 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756087 CCCN(CCC)CCc1ccc(F)c(O)c1 InChI=1S/C14H22FNO/c1-3-8-16(9-4-2)10-7-12-5-6-13(15)14(17)11-12/h5-6,11,17H,3-4,7-10H2,1-2H3 ZVROUTUQLJOEKS-UHFFFAOYSA-N 50010732 5-(2-Dipropylamino-ethyl)-2-fluoro-phenol; hydrobromide::CHEMBL541304 D(2) dopamine receptor Rattus norvegicus 950 ChEMBL 10.1021/jm00171a014 10.7270/Q29G5NFT 1975274 Claudi, F; Cardellini, M; Cingolani, GM; Piergentili, A; Peruzzi, G; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010732&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14901829 103923478 CHEMBL541304 ZINC26489832 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756091 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 2200 ChEMBL 10.1021/jm00171a014 10.7270/Q29G5NFT 1975274 Claudi, F; Cardellini, M; Cingolani, GM; Piergentili, A; Peruzzi, G; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756093 CCCN(CC)CCc1ccc(F)c(O)c1 InChI=1S/C13H20FNO/c1-3-8-15(4-2)9-7-11-5-6-12(14)13(16)10-11/h5-6,10,16H,3-4,7-9H2,1-2H3 QENBOHPMBXBKIA-UHFFFAOYSA-N 50010734 5-[2-(Ethyl-propyl-amino)-ethyl]-2-fluoro-phenol; hydrobromide::CHEMBL540036 D(2) dopamine receptor Rattus norvegicus 1970 ChEMBL 10.1021/jm00171a014 10.7270/Q29G5NFT 1975274 Claudi, F; Cardellini, M; Cingolani, GM; Piergentili, A; Peruzzi, G; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14901827 103923480 CHEMBL540036 ZINC26483402 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756094 NCCc1ccc(F)c(O)c1 InChI=1S/C8H10FNO/c9-7-2-1-6(3-4-10)5-8(7)11/h1-2,5,11H,3-4,10H2 BQDIGRQKBKSZPE-UHFFFAOYSA-N 50010730 5-(2-Amino-ethyl)-2-fluoro-phenol; hydrobromide::CHEMBL545240 D(2) dopamine receptor Rattus norvegicus 4640 ChEMBL 10.1021/jm00171a014 10.7270/Q29G5NFT 1975274 Claudi, F; Cardellini, M; Cingolani, GM; Piergentili, A; Peruzzi, G; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010730&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14901811 103923476 CHEMBL545240 ZINC06525086 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50740986 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3c[nH]c4cc(ccc34)C(F)(F)F)OCCc2c1 InChI=1S/C26H26F3N3O2/c27-26(28,29)19-2-4-21-22(15-31-23(21)14-19)16-5-9-32(10-6-16)11-7-24-20-3-1-18(25(30)33)13-17(20)8-12-34-24/h1-5,13-15,24,31H,6-12H2,(H2,30,33) ULBUUAFUKXEBCK-UHFFFAOYSA-N 50145346 1-{2-[4-(6-Trifluoromethyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL313452 D(2) dopamine receptor Rattus norvegicus 8.6 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461336 104034187 CHEMBL313452 ZINC26498159 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50740990 NC(=O)c1ccc2C(CCN3CCC(CC3)c3c[nH]c4cc(F)ccc34)OCCc2c1 InChI=1S/C25H28FN3O2/c26-19-2-4-21-22(15-28-23(21)14-19)16-5-9-29(10-6-16)11-7-24-20-3-1-18(25(27)30)13-17(20)8-12-31-24/h1-4,13-16,24,28H,5-12H2,(H2,27,30) NCCVKLHAWCZIET-UHFFFAOYSA-N 50145337 1-{2-[4-(6-Fluoro-1H-indol-3-yl)-piperidin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL79674 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461249 104034178 CHEMBL79674 ZINC26495168 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50740992 NC(=O)c1ccc2C(CCN3CCC(CC3)c3cccc4ccccc34)OCCc2c1 InChI=1S/C27H30N2O2/c28-27(30)22-8-9-25-21(18-22)13-17-31-26(25)12-16-29-14-10-20(11-15-29)24-7-3-5-19-4-1-2-6-23(19)24/h1-9,18,20,26H,10-17H2,(H2,28,30) HRZOOXCBXLHFRO-UHFFFAOYSA-N 50145345 1-[2-(4-Naphthalen-1-yl-piperidin-1-yl)-ethyl]-isochroman-6-carboxylic acid amide::CHEMBL79693 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461443 104034186 CHEMBL79693 ZINC26496430 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741001 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3[nH]nc4cc(F)ccc34)OCCc2c1 InChI=1S/C24H25FN4O2/c25-18-2-4-20-21(14-18)27-28-23(20)15-5-9-29(10-6-15)11-7-22-19-3-1-17(24(26)30)13-16(19)8-12-31-22/h1-5,13-14,22H,6-12H2,(H2,26,30)(H,27,28) NPKCLZQNGLZUCO-UHFFFAOYSA-N 50145354 1-{2-[4-(6-Fluoro-1H-indazol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL441259 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145354&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461297 104034195 CHEMBL441259 ZINC26493957 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741002 C[C@H]1CC(CCN1CCC1OCCc2cc(ccc12)C(N)=O)c1c[nH]c2cc(F)ccc12 InChI=1S/C26H30FN3O2/c1-16-12-17(23-15-29-24-14-20(27)3-5-22(23)24)6-9-30(16)10-7-25-21-4-2-19(26(28)31)13-18(21)8-11-32-25/h2-5,13-17,25,29H,6-12H2,1H3,(H2,28,31)/t16-,17?,25?/m0/s1 ZEJSMIRALRRUAZ-YSIXZZNSSA-N 50145338 1-{2-[(S)-4-(6-Fluoro-1H-indol-3-yl)-2-methyl-piperidin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL311787 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461234 104034179 CHEMBL311787 ZINC36237955 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741003 NC(=O)c1ccc2C(CCN3CCC(C3)c3c[nH]c4cc(F)ccc34)OCCc2c1 InChI=1S/C24H26FN3O2/c25-18-2-4-20-21(13-27-22(20)12-18)17-5-8-28(14-17)9-6-23-19-3-1-16(24(26)29)11-15(19)7-10-30-23/h1-4,11-13,17,23,27H,5-10,14H2,(H2,26,29) ASDKFOKSFQKONG-UHFFFAOYSA-N 50145352 1-{2-[3-(6-Fluoro-1H-indol-3-yl)-pyrrolidin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL79725 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461248 104034193 CHEMBL79725 ZINC36237958 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741005 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3c[nH]c4cc(F)ccc34)OCCc2c1 InChI=1S/C25H26FN3O2/c26-19-2-4-21-22(15-28-23(21)14-19)16-5-9-29(10-6-16)11-7-24-20-3-1-18(25(27)30)13-17(20)8-12-31-24/h1-5,13-15,24,28H,6-12H2,(H2,27,30) AYGLZYIWAZBQDC-UHFFFAOYSA-N 50145347 1-(2-(4-(6-fluoro-1H-indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)ethyl)-3,4-dihydro-1H-isochromene-6-carboxamide::1-{2-[4-(6-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL83617 D(2) dopamine receptor Rattus norvegicus 4.7 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9802187 104034188 CHEMBL83617 ZINC03976847 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741006 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3csc4cc(F)ccc34)OCCc2c1 InChI=1S/C25H25FN2O2S/c26-19-2-4-21-22(15-31-24(21)14-19)16-5-9-28(10-6-16)11-7-23-20-3-1-18(25(27)29)13-17(20)8-12-30-23/h1-5,13-15,23H,6-12H2,(H2,27,29) ADEBGCBREGNKQR-UHFFFAOYSA-N 50145336 1-{2-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL81703 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44460810 104034177 CHEMBL81703 ZINC26490199 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741007 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3c[nH]c4c(F)cccc34)OCCc2c1 InChI=1S/C25H26FN3O2/c26-22-3-1-2-20-21(15-28-24(20)22)16-6-10-29(11-7-16)12-8-23-19-5-4-18(25(27)30)14-17(19)9-13-31-23/h1-6,14-15,23,28H,7-13H2,(H2,27,30) PNTQCYZWFHYKJG-UHFFFAOYSA-N 50145349 1-{2-[4-(7-Fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL83112 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461335 104034190 CHEMBL83112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741013 Cn1nc(C2=CCN(CCC3OCCc4cc(ccc34)C(N)=O)CC2)c2ccc(F)cc12 InChI=1S/C25H27FN4O2/c1-29-22-15-19(26)3-5-21(22)24(28-29)16-6-10-30(11-7-16)12-8-23-20-4-2-18(25(27)31)14-17(20)9-13-32-23/h2-6,14-15,23H,7-13H2,1H3,(H2,27,31) MWMKLQFOQVUILF-UHFFFAOYSA-N 50145350 1-{2-[4-(6-Fluoro-1-methyl-1H-indazol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL442974 D(2) dopamine receptor Rattus norvegicus 183 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461168 104034191 CHEMBL442974 ZINC26495827 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741016 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3c[nH]c4c(cccc34)C#N)OCCc2c1 InChI=1S/C26H26N4O2/c27-15-20-2-1-3-22-23(16-29-25(20)22)17-6-10-30(11-7-17)12-8-24-21-5-4-19(26(28)31)14-18(21)9-13-32-24/h1-6,14,16,24,29H,7-13H2,(H2,28,31) PPSMJBTUSUDLMF-UHFFFAOYSA-N 50145357 1-{2-[4-(7-Cyano-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL311694 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145357&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461251 104034198 CHEMBL311694 ZINC26494013 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741022 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3cccc4ccc(F)cc34)OCCc2c1 InChI=1S/C27H27FN2O2/c28-22-6-4-18-2-1-3-23(25(18)17-22)19-8-12-30(13-9-19)14-10-26-24-7-5-21(27(29)31)16-20(24)11-15-32-26/h1-8,16-17,26H,9-15H2,(H2,29,31) XZGSTXKWHGPPEV-UHFFFAOYSA-N 50145353 1-{2-[4-(7-Fluoro-naphthalen-1-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL83732 D(2) dopamine receptor Rattus norvegicus 87 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145353&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461425 104034194 CHEMBL83732 ZINC26500541 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741027 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3noc4cc(F)ccc34)OCCc2c1 InChI=1S/C24H24FN3O3/c25-18-2-4-20-22(14-18)31-27-23(20)15-5-9-28(10-6-15)11-7-21-19-3-1-17(24(26)29)13-16(19)8-12-30-21/h1-5,13-14,21H,6-12H2,(H2,26,29) LIWHOEWNGHFGGB-UHFFFAOYSA-N 50145339 1-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL79853 D(2) dopamine receptor Rattus norvegicus 37 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461149 104034180 CHEMBL79853 ZINC26494494 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741038 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3c[nH]c4c(F)c(F)ccc34)OCCc2c1 InChI=1S/C25H25F2N3O2/c26-21-4-3-19-20(14-29-24(19)23(21)27)15-5-9-30(10-6-15)11-7-22-18-2-1-17(25(28)31)13-16(18)8-12-32-22/h1-5,13-14,22,29H,6-12H2,(H2,28,31) JBFPRZFBWYBGPQ-UHFFFAOYSA-N 50145356 1-{2-[4-(6,7-Difluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL82523 D(2) dopamine receptor Rattus norvegicus 6.7 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461586 104034197 CHEMBL82523 ZINC26503513 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741041 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3ccc4cc(F)ccc4c3)OCCc2c1 InChI=1S/C27H27FN2O2/c28-24-5-3-20-15-19(1-2-21(20)17-24)18-7-11-30(12-8-18)13-9-26-25-6-4-23(27(29)31)16-22(25)10-14-32-26/h1-7,15-17,26H,8-14H2,(H2,29,31) OKKGMDDMZPMRPO-UHFFFAOYSA-N 50145351 1-{2-[4-(6-Fluoro-naphthalen-2-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL310082 D(2) dopamine receptor Rattus norvegicus 491 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461416 104034192 CHEMBL310082 ZINC26491343 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741042 NC(=O)c1ccc2[C@H](CCN3CCC(=CC3)c3c[nH]c4c(F)cccc34)OCCc2c1 InChI=1S/C25H26FN3O2/c26-22-3-1-2-20-21(15-28-24(20)22)16-6-10-29(11-7-16)12-8-23-19-5-4-18(25(27)30)14-17(19)9-13-31-23/h1-6,14-15,23,28H,7-13H2,(H2,27,30)/t23-/m0/s1 PNTQCYZWFHYKJG-QHCPKHFHSA-N 50366907 CHEMBL1169435 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 49799868 160846009 CHEMBL1169435 ZINC26496752 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741044 Cn1cc(C2=CCN(CCC3OCCc4cc(ccc34)C(N)=O)CC2)c2ccc(F)cc12 InChI=1S/C26H28FN3O2/c1-29-16-23(22-5-3-20(27)15-24(22)29)17-6-10-30(11-7-17)12-8-25-21-4-2-19(26(28)31)14-18(21)9-13-32-25/h2-6,14-16,25H,7-13H2,1H3,(H2,28,31) HMBHJNCGAIXIKJ-UHFFFAOYSA-N 50145344 1-{2-[4-(6-Fluoro-1-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL311323 D(2) dopamine receptor Rattus norvegicus 73 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461300 104034185 CHEMBL311323 ZINC03976853 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741046 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3coc4cc(F)ccc34)OCCc2c1 InChI=1S/C25H25FN2O3/c26-19-2-4-21-22(15-31-24(21)14-19)16-5-9-28(10-6-16)11-7-23-20-3-1-18(25(27)29)13-17(20)8-12-30-23/h1-5,13-15,23H,6-12H2,(H2,27,29) URMWJMIKSZNNLQ-UHFFFAOYSA-N 50145343 1-{2-[4-(6-Fluoro-benzofuran-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL82488 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461298 104034184 CHEMBL82488 ZINC26493962 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752236 CN(C)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C14H18N2/c1-16(2)11-5-3-10-4-6-14-12(7-8-15-14)13(10)9-11/h4,6-8,11,15H,3,5,9H2,1-2H3 HENBLLXAHPTGHX-UHFFFAOYSA-N 50017520 (+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine::CHEMBL413105::Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 1840 ChEMBL 10.1021/jm00130a008 10.7270/Q2KD1ZG8 2571729 Wikstrom, H; Andersson, B; Svensson, A; Humber, LG; Asselin, AA; Svensson, K; Ekman, A; Carlsson, A; Nilsson, I; Chidester, C University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129503 103928788 CHEMBL413105 ZINC05965209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752237 CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 InChI=1S/C20H28N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25)/t14-,16+,18+/m0/s1 JOAHPSVPXZTVEP-YXJHDRRASA-N 50017519 1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-urea::CHEMBL73151::Terguride D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm00130a008 10.7270/Q2KD1ZG8 2571729 Wikstrom, H; Andersson, B; Svensson, A; Humber, LG; Asselin, AA; Svensson, K; Ekman, A; Carlsson, A; Nilsson, I; Chidester, C University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 443951 103928787 CHEMBL73151 ZINC03811327 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752241 CN(C)[C@@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C14H18N2/c1-16(2)11-5-3-10-4-6-14-12(7-8-15-14)13(10)9-11/h4,6-8,11,15H,3,5,9H2,1-2H3/t11-/m1/s1 HENBLLXAHPTGHX-LLVKDONJSA-N 50044236 CHEMBL303339::Dimethyl-(R)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::R-(+)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 1050 ChEMBL 10.1021/jm00130a008 10.7270/Q2KD1ZG8 2571729 Wikstrom, H; Andersson, B; Svensson, A; Humber, LG; Asselin, AA; Svensson, K; Ekman, A; Carlsson, A; Nilsson, I; Chidester, C University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044236&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14547414 103975559 CHEMBL303339 ZINC03798324 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752244 CN(C)[C@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C14H18N2/c1-16(2)11-5-3-10-4-6-14-12(7-8-15-14)13(10)9-11/h4,6-8,11,15H,3,5,9H2,1-2H3/t11-/m0/s1 HENBLLXAHPTGHX-NSHDSACASA-N 50044235 CHEMBL292274::Dimethyl-(S)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::S-(-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 9510 ChEMBL 10.1021/jm00130a008 10.7270/Q2KD1ZG8 2571729 Wikstrom, H; Andersson, B; Svensson, A; Humber, LG; Asselin, AA; Svensson, K; Ekman, A; Carlsson, A; Nilsson, I; Chidester, C University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044235&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14547415 103975558 CHEMBL292274 ZINC05965209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752249 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 5760 ChEMBL 10.1021/jm00130a008 10.7270/Q2KD1ZG8 2571729 Wikstrom, H; Andersson, B; Svensson, A; Humber, LG; Asselin, AA; Svensson, K; Ekman, A; Carlsson, A; Nilsson, I; Chidester, C University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758274 COc1ccc(CC(C)NCCCc2ccccc2)cc1 InChI=1S/C19H25NO/c1-16(15-18-10-12-19(21-2)13-11-18)20-14-6-9-17-7-4-3-5-8-17/h3-5,7-8,10-13,16,20H,6,9,14-15H2,1-2H3 PSDOCJRHKUVMFW-UHFFFAOYSA-N 50006967 CHEMBL53170::[2-(4-Methoxy-phenyl)-1-methyl-ethyl]-(3-phenyl-propyl)-amine D(2) dopamine receptor Rattus norvegicus 9320 ChEMBL 10.1021/jm00110a015 10.7270/Q2WW7J9Z 1648139 Glennon, RA; Ismaiel, AM; Smith, JD; Yousif, M; el-Ashmawy, M; Herndon, JL; Fischer, JB; Howie, KJ; Server, AC Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15061885 103920256 CHEMBL53170 ZINC12356006 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758294 C(CNC1CCc2ccccc2CC1)Cc1ccccc1 InChI=1S/C20H25N/c1-2-7-17(8-3-1)9-6-16-21-20-14-12-18-10-4-5-11-19(18)13-15-20/h1-5,7-8,10-11,20-21H,6,9,12-16H2 XMCZQFIGXDUMNK-UHFFFAOYSA-N 50006968 (3-Phenyl-propyl)-(6,7,8,9-tetrahydro-5H-benzocyclohepten-7-yl)-amine::CHEMBL296601 D(2) dopamine receptor Rattus norvegicus 5800 ChEMBL 10.1021/jm00110a015 10.7270/Q2WW7J9Z 1648139 Glennon, RA; Ismaiel, AM; Smith, JD; Yousif, M; el-Ashmawy, M; Herndon, JL; Fischer, JB; Howie, KJ; Server, AC Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006968&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15061905 103920257 CHEMBL296601 ZINC13822230 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758298 CC(Cc1ccc(Cl)c(Cl)c1)NCCCc1ccccc1 InChI=1S/C18H21Cl2N/c1-14(12-16-9-10-17(19)18(20)13-16)21-11-5-8-15-6-3-2-4-7-15/h2-4,6-7,9-10,13-14,21H,5,8,11-12H2,1H3 KSXRUVUAKCZJMP-UHFFFAOYSA-N 50006973 CHEMBL298758::[2-(3,4-Dichloro-phenyl)-1-methyl-ethyl]-(3-phenyl-propyl)-amine D(2) dopamine receptor Rattus norvegicus 1790 ChEMBL 10.1021/jm00110a015 10.7270/Q2WW7J9Z 1648139 Glennon, RA; Ismaiel, AM; Smith, JD; Yousif, M; el-Ashmawy, M; Herndon, JL; Fischer, JB; Howie, KJ; Server, AC Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006973&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15061899 103920262 CHEMBL298758 ZINC13822218 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758315 CC(Cc1ccc(I)cc1)NCCCc1ccccc1 InChI=1S/C18H22IN/c1-15(14-17-9-11-18(19)12-10-17)20-13-5-8-16-6-3-2-4-7-16/h2-4,6-7,9-12,15,20H,5,8,13-14H2,1H3 NVVHZMXNPUHEAQ-UHFFFAOYSA-N 50006970 CHEMBL293952::[2-(4-Iodo-phenyl)-1-methyl-ethyl]-(3-phenyl-propyl)-amine D(2) dopamine receptor Rattus norvegicus 3800 ChEMBL 10.1021/jm00110a015 10.7270/Q2WW7J9Z 1648139 Glennon, RA; Ismaiel, AM; Smith, JD; Yousif, M; el-Ashmawy, M; Herndon, JL; Fischer, JB; Howie, KJ; Server, AC Virginia Commonwealth University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006970&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44298009 103920259 CHEMBL293952 ZINC28225950 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762678 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 367 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762681 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)[nH]2)CC1 InChI=1S/C24H34N4O2/c1-19(2)30-23-8-4-3-7-22(23)27-15-13-26(14-16-27)17-20-10-11-21(25-20)18-28-12-6-5-9-24(28)29/h3-4,7-8,10-11,19,25H,5-6,9,12-18H2,1-2H3 DYGXCHMXCOSULO-UHFFFAOYSA-N 50001861 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL434512 D(2) dopamine receptor Rattus norvegicus 1.6 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724502 103916228 CHEMBL434512 ZINC53267770 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762688 CCCCOc1ccccc1N1CCN(Cc2ccc(CN3CCCCCC3=O)n2C)CC1 InChI=1S/C27H40N4O2/c1-3-4-20-33-26-11-8-7-10-25(26)30-18-16-29(17-19-30)21-23-13-14-24(28(23)2)22-31-15-9-5-6-12-27(31)32/h7-8,10-11,13-14H,3-6,9,12,15-22H2,1-2H3 GDKYCVUEIWJHFP-UHFFFAOYSA-N 50001863 1-{5-[4-(2-Butoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-azepan-2-one::CHEMBL348002 D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724477 103916230 CHEMBL348002 ZINC13449395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762690 CC(C)c1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C25H36N4O/c1-20(2)23-8-4-5-9-24(23)28-16-14-27(15-17-28)18-21-11-12-22(26(21)3)19-29-13-7-6-10-25(29)30/h4-5,8-9,11-12,20H,6-7,10,13-19H2,1-3H3 HJPQWOMFLXBLKB-UHFFFAOYSA-N 50001858 1-{5-[4-(2-Isopropyl-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL155506 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724500 103916225 CHEMBL155506 ZINC53246210 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762691 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 InChI=1S/C24H34N4O2/c1-19(2)30-23-8-5-4-7-22(23)27-15-13-26(14-16-27)17-20-10-11-21(25(20)3)18-28-12-6-9-24(28)29/h4-5,7-8,10-11,19H,6,9,12-18H2,1-3H3 DFWKGWAWWMFKQB-UHFFFAOYSA-N 50001871 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL345506 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724491 103916238 CHEMBL345506 ZINC13449350 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762698 CC(C)c1ccccc1N1CCN(Cc2ccc(CN3CCCCCCC3=O)n2C)CC1 InChI=1S/C27H40N4O/c1-22(2)25-10-7-8-11-26(25)30-18-16-29(17-19-30)20-23-13-14-24(28(23)3)21-31-15-9-5-4-6-12-27(31)32/h7-8,10-11,13-14,22H,4-6,9,12,15-21H2,1-3H3 JZYKCNDXKHXNNL-UHFFFAOYSA-N 50001856 1-{5-[4-(2-Isopropyl-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-azocan-2-one::CHEMBL347782 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724478 103916223 CHEMBL347782 ZINC13449400 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762699 CCOc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 InChI=1S/C23H32N4O2/c1-3-29-22-8-5-4-7-21(22)26-15-13-25(14-16-26)17-19-10-11-20(24(19)2)18-27-12-6-9-23(27)28/h4-5,7-8,10-11H,3,6,9,12-18H2,1-2H3 UFHCMLOWPCFQMX-UHFFFAOYSA-N 50001870 1-{5-[4-(2-Ethoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL348241 D(2) dopamine receptor Rattus norvegicus 9.3 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724490 103916237 CHEMBL348241 ZINC13449347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762700 CCc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C24H34N4O/c1-3-20-8-4-5-9-23(20)27-16-14-26(15-17-27)18-21-11-12-22(25(21)2)19-28-13-7-6-10-24(28)29/h4-5,8-9,11-12H,3,6-7,10,13-19H2,1-2H3 VAIWZWZRCSJKTP-UHFFFAOYSA-N 50001874 1-{5-[4-(2-Ethyl-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL347334 D(2) dopamine receptor Rattus norvegicus 6.7 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15124074 103916241 CHEMBL347334 ZINC53074262 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762701 Cn1c(CN2CCN(CC2)c2cccc(Cl)c2)ccc1CN1CCCCC1=O InChI=1S/C22H29ClN4O/c1-24-20(8-9-21(24)17-27-10-3-2-7-22(27)28)16-25-11-13-26(14-12-25)19-6-4-5-18(23)15-19/h4-6,8-9,15H,2-3,7,10-14,16-17H2,1H3 MCPAGVLBVBGILQ-UHFFFAOYSA-N 50001875 1-{5-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL153451 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001875&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724503 103916242 CHEMBL153451 ZINC53231173 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741053 NC(=O)c1ccc2C(CCN3CCN(CC3)c3c[nH]c4cc(F)ccc34)OCCc2c1 InChI=1S/C24H27FN4O2/c25-18-2-4-20-21(14-18)27-15-22(20)29-10-8-28(9-11-29)7-5-23-19-3-1-17(24(26)30)13-16(19)6-12-31-23/h1-4,13-15,23,27H,5-12H2,(H2,26,30) DPSICFWUAYTGRW-UHFFFAOYSA-N 50145334 1-{2-[4-(6-Fluoro-1H-indol-3-yl)-piperazin-1-yl]-ethyl}-isochroman-6-carboxylic acid amide::CHEMBL310744 D(2) dopamine receptor Rattus norvegicus 7.1 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461247 104034175 CHEMBL310744 ZINC26496622 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50741063 NC(=O)c1ccc2C(CCN3CCC(=CC3)c3cccc4ccccc34)OCCc2c1 InChI=1S/C27H28N2O2/c28-27(30)22-8-9-25-21(18-22)13-17-31-26(25)12-16-29-14-10-20(11-15-29)24-7-3-5-19-4-1-2-6-23(19)24/h1-10,18,26H,11-17H2,(H2,28,30) JNYHVVZVSHDECL-UHFFFAOYSA-N 50145333 1-[2-(4-Naphthalen-1-yl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-isochroman-6-carboxylic acid amide::CHEMBL81191 D(2) dopamine receptor Rattus norvegicus 167 ChEMBL 10.1016/j.bmcl.2004.03.003 10.7270/Q2057GG2 15109634 Timms, GH; Boot, JR; Broadmore, RJ; Carney, SL; Cooper, J; Findlay, JD; Gilmore, J; Mitchell, S; Moore, NA; Pullar, I; Sanger, GJ; Tomlinson, R; Tree, BB; Wedley, S Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145333&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10070281 104034174 CHEMBL81191 ZINC26496438 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752339 CN1CCN(CC1)C1=Nc2cc(ccc2Nc2nn(C)cc12)C(F)(F)F InChI=1S/C17H19F3N6/c1-24-5-7-26(8-6-24)16-12-10-25(2)23-15(12)21-13-4-3-11(17(18,19)20)9-14(13)22-16/h3-4,9-10H,5-8H2,1-2H3,(H,21,23) MJDDCQXVUIFPIZ-UHFFFAOYSA-N 50017613 2-Methyl-10-(4-methyl-piperazin-1-yl)-7-trifluoromethyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL314787 D(2) dopamine receptor Rattus norvegicus 1600 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017613&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888787 103928881 CHEMBL314787 ZINC26575626 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752340 CN1CCN(CC1)C1=Nc2cc(F)c(F)cc2Nc2nn(C)cc12 InChI=1S/C16H18F2N6/c1-22-3-5-24(6-4-22)16-10-9-23(2)21-15(10)19-13-7-11(17)12(18)8-14(13)20-16/h7-9H,3-6H2,1-2H3,(H,19,21) ALXJJOOZCXXJCK-UHFFFAOYSA-N 50017617 6,7-Difluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL87726 D(2) dopamine receptor Rattus norvegicus 760 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888798 103928885 CHEMBL87726 ZINC26576188 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752341 CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2c(C)nn(C)c12 InChI=1S/C17H21FN6/c1-11-15-16(23(3)21-11)17(24-8-6-22(2)7-9-24)20-14-10-12(18)4-5-13(14)19-15/h4-5,10,19H,6-9H2,1-3H3 JTRJPPCZYWBOLW-UHFFFAOYSA-N 50017621 7-Fluoro-1,3-dimethyl-10-(4-methyl-piperazin-1-yl)-1,4-dihydro-1,2,4,9-tetraaza-benzo[f]azulene::CHEMBL313555 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017621&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590622 103928889 CHEMBL313555 ZINC26573913 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752342 CCn1cc2c(Nc3cc(Cl)c(Cl)cc3N=C2N2CCN(C)CC2)n1 InChI=1S/C17H20Cl2N6/c1-3-25-10-11-16(22-25)20-14-8-12(18)13(19)9-15(14)21-17(11)24-6-4-23(2)5-7-24/h8-10H,3-7H2,1-2H3,(H,20,22) HCQLXDPSICPBJU-UHFFFAOYSA-N 50017622 6,7-Dichloro-2-ethyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL312849 D(2) dopamine receptor Rattus norvegicus 3800 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017622&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590619 103928890 CHEMBL312849 ZINC26574882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752343 CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2nn(C)c(c12)-c1ccccc1 InChI=1S/C22H23FN6/c1-27-10-12-29(13-11-27)22-19-20(15-6-4-3-5-7-15)28(2)26-21(19)24-17-9-8-16(23)14-18(17)25-22/h3-9,14H,10-13H2,1-2H3,(H,24,26) WRBPSBMXXGKKNA-UHFFFAOYSA-N 50017627 7-Fluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-1-phenyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL315620 D(2) dopamine receptor Rattus norvegicus 2100 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017627&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590614 103928895 CHEMBL315620 ZINC26573922 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752344 CCn1cc2c(Nc3ccc(Cl)cc3N=C2N2CCN(C)CC2)n1 InChI=1S/C17H21ClN6/c1-3-24-11-13-16(21-24)19-14-5-4-12(18)10-15(14)20-17(13)23-8-6-22(2)7-9-23/h4-5,10-11H,3,6-9H2,1-2H3,(H,19,21) DOZKGRLEQYKHHD-UHFFFAOYSA-N 50017615 7-Chloro-2-ethyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL421879 D(2) dopamine receptor Rattus norvegicus 340 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017615&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888790 103928883 CHEMBL421879 ZINC26576289 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752345 CCCCCCn1cc2c(Nc3ccc(F)cc3N=C2N2CCN(C)CC2)n1 InChI=1S/C21H29FN6/c1-3-4-5-6-9-28-15-17-20(25-28)23-18-8-7-16(22)14-19(18)24-21(17)27-12-10-26(2)11-13-27/h7-8,14-15H,3-6,9-13H2,1-2H3,(H,23,25) JGMNCJGJBLFTHK-UHFFFAOYSA-N 50017626 7-Fluoro-2-hexyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene; hydrochloride::CHEMBL545247 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017626&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888795 103928894 CHEMBL545247 ZINC26575340 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752346 Cn1cc2c(Nc3ccc(F)cc3N=C2N2CC[N+](C)([O-])CC2)n1 InChI=1S/C16H19FN6O/c1-21-10-12-15(20-21)18-13-4-3-11(17)9-14(13)19-16(12)22-5-7-23(2,24)8-6-22/h3-4,9-10H,5-8H2,1-2H3,(H,18,20) ODDAGPPBKZRYEU-UHFFFAOYSA-N 50017624 7-Fluoro-2-methyl-10-(4-methyl-4-oxy-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL316032 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017624&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888801 103928892 CHEMBL316032 ZINC26577046 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752347 Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCN(CC3CC3)CC2)n1 InChI=1S/C19H23FN6/c1-24-12-15-18(23-24)21-16-5-4-14(20)10-17(16)22-19(15)26-8-6-25(7-9-26)11-13-2-3-13/h4-5,10,12-13H,2-3,6-9,11H2,1H3,(H,21,23) ZEBMXWFZKAPFND-UHFFFAOYSA-N 50017633 10-(4-Cyclopropylmethyl-piperazin-1-yl)-7-fluoro-2-methyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL87869 D(2) dopamine receptor Rattus norvegicus 900 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017633&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888803 103928901 CHEMBL87869 ZINC26576073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752348 CCCn1cc2c(Nc3ccc(F)cc3N=C2N2CCN(C)CC2)n1 InChI=1S/C18H23FN6/c1-3-6-25-12-14-17(22-25)20-15-5-4-13(19)11-16(15)21-18(14)24-9-7-23(2)8-10-24/h4-5,11-12H,3,6-10H2,1-2H3,(H,20,22) RQHXFSWHDAJVFR-UHFFFAOYSA-N 50017634 7-Fluoro-10-(4-methyl-piperazin-1-yl)-2-propyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL315007 D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017634&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888797 103928902 CHEMBL315007 ZINC26574134 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752349 CC(C)n1cc2c(Nc3ccc(F)cc3N=C2N2CCN(C)CC2)n1 InChI=1S/C18H23FN6/c1-12(2)25-11-14-17(22-25)20-15-5-4-13(19)10-16(15)21-18(14)24-8-6-23(3)7-9-24/h4-5,10-12H,6-9H2,1-3H3,(H,20,22) OUUAJIUTRKTKJF-UHFFFAOYSA-N 50017635 7-Fluoro-2-isopropyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL313662 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017635&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888796 103928903 CHEMBL313662 ZINC26575523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752350 CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2nn(C)cc12 InChI=1S/C16H19FN6/c1-21-5-7-23(8-6-21)16-12-10-22(2)20-15(12)18-13-4-3-11(17)9-14(13)19-16/h3-4,9-10H,5-8H2,1-2H3,(H,18,20) MYODITQJTYGHII-UHFFFAOYSA-N 50017636 7-Fluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL313661 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888785 103928904 CHEMBL313661 ZINC26575496 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752351 CC(C)Cn1cc2c(Nc3ccc(Cl)cc3N=C2N2CCN(C)CC2)n1 InChI=1S/C19H25ClN6/c1-13(2)11-26-12-15-18(23-26)21-16-5-4-14(20)10-17(16)22-19(15)25-8-6-24(3)7-9-25/h4-5,10,12-13H,6-9,11H2,1-3H3,(H,21,23) MGVUFBYZICTODX-UHFFFAOYSA-N 50017637 7-Chloro-2-isobutyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL82871 D(2) dopamine receptor Rattus norvegicus 3300 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888789 103928905 CHEMBL82871 ZINC26573669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752352 CCCCCCCCCCn1cc2c(Nc3ccc(Cl)cc3N=C2N2CCN(C)CC2)n1 InChI=1S/C25H37ClN6/c1-3-4-5-6-7-8-9-10-13-32-19-21-24(29-32)27-22-12-11-20(26)18-23(22)28-25(21)31-16-14-30(2)15-17-31/h11-12,18-19H,3-10,13-17H2,1-2H3,(H,27,29) TZKQJTIXILVLND-UHFFFAOYSA-N 50017638 7-Chloro-2-decyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL410143 D(2) dopamine receptor Rattus norvegicus 2500 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590617 103928906 CHEMBL410143 ZINC36093060 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752353 CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2nn(Cc3ccccc3)cc12 InChI=1S/C22H23FN6/c1-27-9-11-28(12-10-27)22-18-15-29(14-16-5-3-2-4-6-16)26-21(18)24-19-8-7-17(23)13-20(19)25-22/h2-8,13,15H,9-12,14H2,1H3,(H,24,26) QKQSKLHSYVEDTO-UHFFFAOYSA-N 50017631 2-Benzyl-7-fluoro-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL316193 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017631&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590616 103928899 CHEMBL316193 ZINC26573919 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752354 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2nn(C)cc12 InChI=1S/C16H19ClN6/c1-21-5-7-23(8-6-21)16-12-10-22(2)20-15(12)18-13-4-3-11(17)9-14(13)19-16/h3-4,9-10H,5-8H2,1-2H3,(H,18,20) LBZWPAIXXRQBFP-UHFFFAOYSA-N 50017630 7-Chloro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL84577 D(2) dopamine receptor Rattus norvegicus 680 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017630&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888786 103928898 CHEMBL84577 ZINC26576554 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752355 CN1CCN(CC1)C1=Nc2ccc(F)cc2Nc2nn(C)cc12 InChI=1S/C16H19FN6/c1-21-5-7-23(8-6-21)16-12-10-22(2)20-15(12)18-14-9-11(17)3-4-13(14)19-16/h3-4,9-10H,5-8H2,1-2H3,(H,18,20) SZLWYBMHEQYOCI-UHFFFAOYSA-N 50017641 6-Fluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL86870 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017641&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888799 103928909 CHEMBL86870 ZINC26576852 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752356 Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCN(CCO)CC2)n1 InChI=1S/C17H21FN6O/c1-22-11-13-16(21-22)19-14-3-2-12(18)10-15(14)20-17(13)24-6-4-23(5-7-24)8-9-25/h2-3,10-11,25H,4-9H2,1H3,(H,19,21) ALLHAQPRFMVUDM-UHFFFAOYSA-N 50017623 2-[4-(7-Fluoro-2-methyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulen-10-yl)-piperazin-1-yl]-ethanol::CHEMBL313370 D(2) dopamine receptor Rattus norvegicus 5100 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017623&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590628 103928891 CHEMBL313370 ZINC26576515 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752357 CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2sc(C)cc12 InChI=1S/C17H19FN4S/c1-11-9-13-16(22-7-5-21(2)6-8-22)19-15-10-12(18)3-4-14(15)20-17(13)23-11/h3-4,9-10,20H,5-8H2,1-2H3 JBHUBOISLBWHAR-UHFFFAOYSA-N 50017536 (Flumezapine)7-Fluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene::7-Fluoro-2-methyl-10-(4-methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene::CHEMBL273786::Flumezapine D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017536&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 43602 103928804 CHEMBL273786 ZINC30690658 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752358 CN1CCN(CC1)C1=Nc2ccc(C)cc2Nc2nn(C)cc12 InChI=1S/C17H22N6/c1-12-4-5-14-15(10-12)18-16-13(11-22(3)20-16)17(19-14)23-8-6-21(2)7-9-23/h4-5,10-11H,6-9H2,1-3H3,(H,18,20) YTNUVPKKCXITHQ-UHFFFAOYSA-N 50017643 2,6-Dimethyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL87629 D(2) dopamine receptor Rattus norvegicus 5600 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590615 103928911 CHEMBL87629 ZINC26576186 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752359 Cn1cc2c(Nc3ccc(Cl)cc3N=C2N)n1 InChI=1S/C11H10ClN5/c1-17-5-7-10(13)14-9-4-6(12)2-3-8(9)15-11(7)16-17/h2-5H,1H3,(H2,13,14)(H,15,16) XGECVIALSVGJCT-UHFFFAOYSA-N 50017614 7-Chloro-2-methyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulen-10-ylamine::CHEMBL86265 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888808 103928882 CHEMBL86265 ZINC26573580 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752360 Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCOCC2)n1 InChI=1S/C15H16FN5O/c1-20-9-11-14(19-20)17-12-3-2-10(16)8-13(12)18-15(11)21-4-6-22-7-5-21/h2-3,8-9H,4-7H2,1H3,(H,17,19) CLBYMEHHRUIOGC-UHFFFAOYSA-N 50017616 7-Fluoro-2-methyl-10-morpholin-4-yl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL87564 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017616&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590632 103928884 CHEMBL87564 ZINC26575620 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752361 CN1CCN(CC1)C1=Nc2cc(Cl)c(Cl)cc2Nc2nn(C)cc12 InChI=1S/C16H18Cl2N6/c1-22-3-5-24(6-4-22)16-10-9-23(2)21-15(10)19-13-7-11(17)12(18)8-14(13)20-16/h7-9H,3-6H2,1-2H3,(H,19,21) YRASTUQIHBHSPV-UHFFFAOYSA-N 50017645 6,7-Dichloro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL315131 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017645&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888792 103928913 CHEMBL315131 ZINC26576961 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752362 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752363 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2nn(cc12)C1CCCC1 InChI=1S/C20H25ClN6/c1-25-8-10-26(11-9-25)20-16-13-27(15-4-2-3-5-15)24-19(16)22-17-7-6-14(21)12-18(17)23-20/h6-7,12-13,15H,2-5,8-11H2,1H3,(H,22,24) FGIWRGQKBCZMMU-UHFFFAOYSA-N 50017646 7-Chloro-2-cyclopentyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL87384 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017646&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888788 103928914 CHEMBL87384 ZINC26575176 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752364 CCn1cc2c(Nc3ccc(F)cc3N=C2N2CCN(C)CC2)n1 InChI=1S/C17H21FN6/c1-3-24-11-13-16(21-24)19-14-5-4-12(18)10-15(14)20-17(13)23-8-6-22(2)7-9-23/h4-5,10-11H,3,6-9H2,1-2H3,(H,19,21) JLYHIQOGBOUJJO-UHFFFAOYSA-N 50017648 2-Ethyl-7-fluoro-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL86753 D(2) dopamine receptor Rattus norvegicus 3300 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888800 103928916 CHEMBL86753 ZINC26576879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752365 CN1CCN(CC1)C1=Nc2cc(Br)ccc2Nc2nn(C)cc12 InChI=1S/C16H19BrN6/c1-21-5-7-23(8-6-21)16-12-10-22(2)20-15(12)18-13-4-3-11(17)9-14(13)19-16/h3-4,9-10H,5-8H2,1-2H3,(H,18,20) IYGACQNPUQTXDA-UHFFFAOYSA-N 50017628 7-Bromo-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL86484 D(2) dopamine receptor Rattus norvegicus 680 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017628&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888791 103928896 CHEMBL86484 ZINC26576962 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752366 CN1CCN(CC1)C1=Nc2cccc(Cl)c2Nc2nn(C)cc12 InChI=1S/C16H19ClN6/c1-21-6-8-23(9-7-21)16-11-10-22(2)20-15(11)19-14-12(17)4-3-5-13(14)18-16/h3-5,10H,6-9H2,1-2H3,(H,19,20) KCRJVEPVZNGUGC-UHFFFAOYSA-N 50017647 5-Chloro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL86731 D(2) dopamine receptor Rattus norvegicus 4700 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590618 103928915 CHEMBL86731 ZINC26576340 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752367 CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2nn(C)c(C)c12 InChI=1S/C17H21FN6/c1-11-15-16(21-23(11)3)19-13-5-4-12(18)10-14(13)20-17(15)24-8-6-22(2)7-9-24/h4-5,10H,6-9H2,1-3H3,(H,19,21) PHJXRGDWGHAIHA-UHFFFAOYSA-N 50017619 7-Fluoro-1,2-dimethyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL86782 D(2) dopamine receptor Rattus norvegicus 97000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017619&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888806 103928887 CHEMBL86782 ZINC26576853 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752368 CN1CCN(CC1)C1=Nc2c(Cl)cccc2Nc2nn(C)cc12 InChI=1S/C16H19ClN6/c1-21-6-8-23(9-7-21)16-11-10-22(2)20-15(11)18-13-5-3-4-12(17)14(13)19-16/h3-5,10H,6-9H2,1-2H3,(H,18,20) YWNBIWYKHZHOMI-UHFFFAOYSA-N 50017644 8-Chloro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL86460 D(2) dopamine receptor Rattus norvegicus 860 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888804 103928912 CHEMBL86460 ZINC26575524 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752369 CCOC(=O)N1CCN(CC1)C1=Nc2cc(F)ccc2Nc2nn(C)cc12 InChI=1S/C18H21FN6O2/c1-3-27-18(26)25-8-6-24(7-9-25)17-13-11-23(2)22-16(13)20-14-5-4-12(19)10-15(14)21-17/h4-5,10-11H,3,6-9H2,1-2H3,(H,20,22) GBRDDIIRPZYCJH-UHFFFAOYSA-N 50017632 4-(7-Fluoro-2-methyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulen-10-yl)-piperazine-1-carboxylic acid ethyl ester::CHEMBL446670 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017632&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590629 103928900 CHEMBL446670 ZINC26575525 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752370 CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2c(C)n(C)nc12 InChI=1S/C17H21FN6/c1-11-15-16(21-23(11)3)17(24-8-6-22(2)7-9-24)20-14-10-12(18)4-5-13(14)19-15/h4-5,10,19H,6-9H2,1-3H3 ZVOOGDDDAQCDTD-UHFFFAOYSA-N 50017649 7-Fluoro-2,3-dimethyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-1,2,4,9-tetraaza-benzo[f]azulene::CHEMBL315741 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590623 103928917 CHEMBL315741 ZINC26575497 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752371 CN1CCN(CC1)C1=Nc2cc(F)ccc2Nc2nn(cc12)-c1ccccc1 InChI=1S/C21H21FN6/c1-26-9-11-27(12-10-26)21-17-14-28(16-5-3-2-4-6-16)25-20(17)23-18-8-7-15(22)13-19(18)24-21/h2-8,13-14H,9-12H2,1H3,(H,23,25) BRPYQZBXHSAXJM-UHFFFAOYSA-N 50017650 7-Fluoro-10-(4-methyl-piperazin-1-yl)-2-phenyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL86380 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017650&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590613 103928918 CHEMBL86380 ZINC26576428 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756451 Oc1ccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c2c1O InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m1/s1 XEXUKNQDDPKEIF-OAHLLOKOSA-N 50007423 (R)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol; hydrobromide::CHEMBL318111::CHEMBL542493::cid_11957524 D(2) dopamine receptor Rattus norvegicus 0.240000 ChEMBL 10.1021/jm00105a005 10.7270/Q24Q7VKQ 1671415 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007423&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 838674 103920698 CHEMBL318111CHEMBL542493 ZINC00366660 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756455 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 0.800000 ChEMBL 10.1021/jm00105a005 10.7270/Q24Q7VKQ 1671415 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756457 CCCN1CCc2cccc-3c2[C@@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m0/s1 BTGAJCKRXPNBFI-HNNXBMFYSA-N 50007425 (S) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(S)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(S)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL330274 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm00105a005 10.7270/Q24Q7VKQ 1671415 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007425&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311191 103920700 CHEMBL330274 ZINC01735106 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756458 Oc1cccc2C[C@H]3N(CC=C)CCc4cccc(c34)-c12 InChI=1S/C19H19NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h2-8,16,21H,1,9-12H2/t16-/m1/s1 AUVXRDCLWMODQH-MRXNPFEDSA-N 50368145 CHEMBL1788212 D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1021/jm00105a005 10.7270/Q24Q7VKQ 1671415 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368145&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3083157 160847247 CHEMBL1788212 ZINC13860705 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756463 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m1/s1 WZJSIHGOLMMBAL-MRXNPFEDSA-N 84636 CHEMBL27559::NPA-11-OH-R,(+) D(2) dopamine receptor Rattus norvegicus 0.900000 ChEMBL 10.1021/jm00105a005 10.7270/Q24Q7VKQ 1671415 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333842 136350736 CHEMBL27559 ZINC05833984 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756465 Oc1ccc2C[C@@H]3N(CC=C)CCc4cccc(c34)-c2c1O InChI=1S/C19H19NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h2-7,15,21-22H,1,8-11H2/t15-/m0/s1 XEXUKNQDDPKEIF-HNNXBMFYSA-N 50007424 (S)6-Allyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL319557 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00105a005 10.7270/Q24Q7VKQ 1671415 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007424&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15136 103920699 CHEMBL319557 ZINC02039533 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756467 Oc1cccc2C[C@@H]3N(CC=C)CCc4cccc(c34)-c12 InChI=1S/C19H19NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h2-8,16,21H,1,9-12H2/t16-/m0/s1 AUVXRDCLWMODQH-INIZCTEOSA-N 50368144 CHEMBL1744043 D(2) dopamine receptor Rattus norvegicus 155 ChEMBL 10.1021/jm00105a005 10.7270/Q24Q7VKQ 1671415 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368144&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5748459 160847246 CHEMBL1744043 ZINC13860706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756473 CCCN1CCc2cccc-3c2[C@@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m0/s1 WZJSIHGOLMMBAL-INIZCTEOSA-N 50023739 (S)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL283489 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm00105a005 10.7270/Q24Q7VKQ 1671415 Neumeyer, JL; Gao, YG; Kula, NS; Baldessarini, RJ Northeastern University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023739&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13922235 103934080 CHEMBL283489 ZINC05833961 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756476 O=c1ccoc2cc(OCCCN3CCN(CC3)c3ccccn3)ccc12 InChI=1S/C21H23N3O3/c25-19-7-15-27-20-16-17(5-6-18(19)20)26-14-3-9-23-10-12-24(13-11-23)21-4-1-2-8-22-21/h1-2,4-8,15-16H,3,9-14H2 NVGYZBZAFVGARK-UHFFFAOYSA-N 50007428 7-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-chromen-4-one::CHEMBL84639 D(2) dopamine receptor Rattus norvegicus 1080 ChEMBL 10.1021/jm00105a039 10.7270/Q20Z73WT 1671416 Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007428&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 147080 103920703 CHEMBL84639 ZINC26570727 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756488 CCN1CCC[C@@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m1/s1 BGRJTUBHPOOWDU-LLVKDONJSA-N 81775 Sulpiride-R::Sulpiride-d::Sulpiride-high,(-)::Sulpiride-low,(-) D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 643497 131342349 64122 960 ZINC00020229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756498 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm00105a041 10.7270/Q2W959SQ 1825115 Murakami, S; Marubayashi, N; Fukuda, T; Takehara, S; Tahara, T Yoshitomi Pharmaceutical Industries Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50760503 CCCN1CCCC(C1)c1ccccc1O InChI=1S/C14H21NO/c1-2-9-15-10-5-6-12(11-15)13-7-3-4-8-14(13)16/h3-4,7-8,12,16H,2,5-6,9-11H2,1H3 IPSFGCUUHLOCEI-UHFFFAOYSA-N 50002126 2-(1-Propyl-piperidin-3-yl)-phenol::CHEMBL104987 D(2) dopamine receptor Rattus norvegicus 7000 ChEMBL 10.1021/jm00094a019 10.7270/Q2JD4XDS 1354263 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Lograno, MD; Daniele, E; Govoni, S Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002126&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937949 103916435 CHEMBL104987 ZINC26829431 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50760508 CCCN1CCCC(C1)c1ccccc1OC InChI=1S/C15H23NO/c1-3-10-16-11-6-7-13(12-16)14-8-4-5-9-15(14)17-2/h4-5,8-9,13H,3,6-7,10-12H2,1-2H3 UGSUUBPXDJGUAQ-UHFFFAOYSA-N 50002130 3-(2-Methoxy-phenyl)-1-propyl-piperidine::3-(2-Methoxy-phenyl)-1-propyl-piperidine;HCl::CHEMBL285709 D(2) dopamine receptor Rattus norvegicus 8000 ChEMBL 10.1021/jm00094a019 10.7270/Q2JD4XDS 1354263 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Lograno, MD; Daniele, E; Govoni, S Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002130&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937938 103916439 CHEMBL285709 ZINC29235143 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50760509 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm00094a019 10.7270/Q2JD4XDS 1354263 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Lograno, MD; Daniele, E; Govoni, S Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762702 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCCC3=O)n2C)CC1 InChI=1S/C26H38N4O2/c1-21(2)32-25-10-7-6-9-24(25)29-17-15-28(16-18-29)19-22-12-13-23(27(22)3)20-30-14-8-4-5-11-26(30)31/h6-7,9-10,12-13,21H,4-5,8,11,14-20H2,1-3H3 VKPKXWTZHUMWST-UHFFFAOYSA-N 50001876 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-azepan-2-one::CHEMBL152311 D(2) dopamine receptor Rattus norvegicus 0.450000 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001876&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724476 103916243 CHEMBL152311 ZINC13449392 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762703 CCc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 InChI=1S/C23H32N4O/c1-3-19-7-4-5-8-22(19)26-15-13-25(14-16-26)17-20-10-11-21(24(20)2)18-27-12-6-9-23(27)28/h4-5,7-8,10-11H,3,6,9,12-18H2,1-2H3 GTKMLSMARUAOQQ-UHFFFAOYSA-N 50001864 1-{5-[4-(2-Ethyl-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL153335 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724483 103916231 CHEMBL153335 ZINC13449326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762711 COc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2-c2ccccc2)CC1 InChI=1S/C27H32N4O2/c1-33-26-11-6-5-10-25(26)29-18-16-28(17-19-29)20-23-13-14-24(21-30-15-7-12-27(30)32)31(23)22-8-3-2-4-9-22/h2-6,8-11,13-14H,7,12,15-21H2,1H3 WNRMEBFGFQNTLL-UHFFFAOYSA-N 50001880 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-phenyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL152424 D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001880&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724489 103916247 CHEMBL152424 ZINC13449344 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762717 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762719 COc1ccccc1N1CCN(Cc2ccc(CN3CCCCCCC3=O)n2C)CC1 InChI=1S/C25H36N4O2/c1-26-21(12-13-22(26)20-29-14-8-4-3-5-11-25(29)30)19-27-15-17-28(18-16-27)23-9-6-7-10-24(23)31-2/h6-7,9-10,12-13H,3-5,8,11,14-20H2,1-2H3 IXXYHUVMEBTGED-UHFFFAOYSA-N 50001860 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-azocan-2-one::CHEMBL347056 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001860&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724479 103916227 CHEMBL347056 ZINC13449403 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762722 Cn1c(CN2CCCC2=O)ccc1CN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C21H27ClN4O/c1-23-19(7-8-20(23)16-26-9-3-6-21(26)27)15-24-10-12-25(13-11-24)18-5-2-4-17(22)14-18/h2,4-5,7-8,14H,3,6,9-13,15-16H2,1H3 WDDZMYMPOOXFJZ-UHFFFAOYSA-N 50001872 1-{5-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL357532 D(2) dopamine receptor Rattus norvegicus 101 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724495 103916239 CHEMBL357532 ZINC13449365 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762728 COc1ccccc1N1CCNCC1 InChI=1S/C11H16N2O/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3 VNZLQLYBRIOLFZ-UHFFFAOYSA-N 50001862 (N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl)-piperazine::1-(2-Methoxy-phenyl)-piperazine::2-METHOXYPHENYLPIPERAZINE::4-(2-Methoxy-phenyl)-piperazin-1-ium::CHEMBL9666 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1346 103916229 CHEMBL9666 280 ZINC00012687 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762730 COc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 InChI=1S/C22H30N4O2/c1-23-18(9-10-19(23)17-26-11-5-8-22(26)27)16-24-12-14-25(15-13-24)20-6-3-4-7-21(20)28-2/h3-4,6-7,9-10H,5,8,11-17H2,1-2H3 ODMHGYCMTWTSGP-UHFFFAOYSA-N 50001883 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL153490 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001883&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724488 103916250 CHEMBL153490 ZINC13449341 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762731 Cn1c(CN2CCCC2=O)ccc1CN1CCN(CC1)c1cccc(c1)C(F)(F)F InChI=1S/C22H27F3N4O/c1-26-19(7-8-20(26)16-29-9-3-6-21(29)30)15-27-10-12-28(13-11-27)18-5-2-4-17(14-18)22(23,24)25/h2,4-5,7-8,14H,3,6,9-13,15-16H2,1H3 HKPMQBGPHOLNJP-UHFFFAOYSA-N 50001877 1-{1-Methyl-5-[4-(3-trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL153219 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001877&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724497 103916244 CHEMBL153219 ZINC13449371 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762732 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCCCC3=O)n2C)CC1 InChI=1S/C27H40N4O2/c1-22(2)33-26-11-8-7-10-25(26)30-18-16-29(17-19-30)20-23-13-14-24(28(23)3)21-31-15-9-5-4-6-12-27(31)32/h7-8,10-11,13-14,22H,4-6,9,12,15-21H2,1-3H3 SJPZXDLVLGJNJW-UHFFFAOYSA-N 50001855 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-azocan-2-one::CHEMBL346168 D(2) dopamine receptor Rattus norvegicus 0.650000 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724480 103916222 CHEMBL346168 ZINC13449406 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762736 COc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)[nH]2)CC1 InChI=1S/C21H28N4O2/c1-27-20-6-3-2-5-19(20)24-13-11-23(12-14-24)15-17-8-9-18(22-17)16-25-10-4-7-21(25)26/h2-3,5-6,8-9,22H,4,7,10-16H2,1H3 KRIRDNNIESRWGA-UHFFFAOYSA-N 50001867 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL152336 D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724487 103916234 CHEMBL152336 ZINC13449336 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762739 COc1ccccc1N1CCN(Cc2ccc(CN3CCCCCC3=O)n2C)CC1 InChI=1S/C24H34N4O2/c1-25-20(11-12-21(25)19-28-13-7-3-4-10-24(28)29)18-26-14-16-27(17-15-26)22-8-5-6-9-23(22)30-2/h5-6,8-9,11-12H,3-4,7,10,13-19H2,1-2H3 JZPBMEODQISYNB-UHFFFAOYSA-N 50001857 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-azepan-2-one::CHEMBL152363 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724475 103916224 CHEMBL152363 ZINC13449387 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762742 Cn1c(CN2CCCC2=O)ccc1CN1CCN(CC1)c1cccc(F)c1 InChI=1S/C21H27FN4O/c1-23-19(7-8-20(23)16-26-9-3-6-21(26)27)15-24-10-12-25(13-11-24)18-5-2-4-17(22)14-18/h2,4-5,7-8,14H,3,6,9-13,15-16H2,1H3 MSFQABHSNMTPKD-UHFFFAOYSA-N 50001887 1-{5-[4-(3-Fluoro-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL346881 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001887&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724496 103916254 CHEMBL346881 ZINC13449368 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762746 Cc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 InChI=1S/C22H30N4O/c1-18-6-3-4-7-21(18)25-14-12-24(13-15-25)16-19-9-10-20(23(19)2)17-26-11-5-8-22(26)27/h3-4,6-7,9-10H,5,8,11-17H2,1-2H3 IHWWUTUWDXAPEO-UHFFFAOYSA-N 50001882 1-[1-Methyl-5-(4-o-tolyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethyl]-pyrrolidin-2-one::CHEMBL151966 D(2) dopamine receptor Rattus norvegicus 167 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001882&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724482 103916249 CHEMBL151966 ZINC12356217 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762747 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762751 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C25H36N4O2/c1-20(2)31-24-9-5-4-8-23(24)28-16-14-27(15-17-28)18-21-11-12-22(26(21)3)19-29-13-7-6-10-25(29)30/h4-5,8-9,11-12,20H,6-7,10,13-19H2,1-3H3 BLFPEKXTSDYQOQ-UHFFFAOYSA-N 50001869 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL428175::RWJ-25730 D(2) dopamine receptor Rattus norvegicus 0.800000 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9910257 103916236 CHEMBL428175 ZINC53255684 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762752 Cn1c(CN2CCCC2=O)ccc1CN1CCN(CC1)c1ccccc1O InChI=1S/C21H28N4O2/c1-22-17(8-9-18(22)16-25-10-4-7-21(25)27)15-23-11-13-24(14-12-23)19-5-2-3-6-20(19)26/h2-3,5-6,8-9,26H,4,7,10-16H2,1H3 YZSKSIBYNQHPBG-UHFFFAOYSA-N 50001891 1-{5-[4-(2-Hydroxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL152617 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001891&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724492 103916258 CHEMBL152617 ZINC13449355 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762753 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762760 CCCc1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 InChI=1S/C24H34N4O/c1-3-7-20-8-4-5-9-23(20)27-16-14-26(15-17-27)18-21-11-12-22(25(21)2)19-28-13-6-10-24(28)29/h4-5,8-9,11-12H,3,6-7,10,13-19H2,1-2H3 VFYIFYPQQPJZIN-UHFFFAOYSA-N 50001878 1-{1-Methyl-5-[4-(2-propyl-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL348014 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001878&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724484 103916245 CHEMBL348014 ZINC13449329 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762761 CCC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C26H38N4O2/c1-4-21(2)32-25-10-6-5-9-24(25)29-17-15-28(16-18-29)19-22-12-13-23(27(22)3)20-30-14-8-7-11-26(30)31/h5-6,9-10,12-13,21H,4,7-8,11,14-20H2,1-3H3 CERMMWURJWEJSR-UHFFFAOYSA-N 50001889 1-{5-[4-(2-sec-Butoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL153136 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001889&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15124076 103916256 CHEMBL153136 ZINC53231057 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762762 Cn1c(CN2CCCC2=O)ccc1CN1CCN(CC1)c1ccccc1C#N InChI=1S/C22H27N5O/c1-24-19(8-9-20(24)17-27-10-4-7-22(27)28)16-25-11-13-26(14-12-25)21-6-3-2-5-18(21)15-23/h2-3,5-6,8-9H,4,7,10-14,16-17H2,1H3 BOUFCEMVEPFIPT-UHFFFAOYSA-N 50001868 2-{4-[1-Methyl-5-(2-oxo-pyrrolidin-1-ylmethyl)-1H-pyrrol-2-ylmethyl]-piperazin-1-yl}-benzonitrile::CHEMBL152204 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001868&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724494 103916235 CHEMBL152204 ZINC13449362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762763 Cn1c(CN2CCCC2=O)ccc1CN1CCN(CC1)c1ccccc1Cl InChI=1S/C21H27ClN4O/c1-23-17(8-9-18(23)16-26-10-4-7-21(26)27)15-24-11-13-25(14-12-24)20-6-3-2-5-19(20)22/h2-3,5-6,8-9H,4,7,10-16H2,1H3 RIWSLMCCDAXDQC-UHFFFAOYSA-N 50001892 1-{5-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL152867 D(2) dopamine receptor Rattus norvegicus >80 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001892&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724493 103916259 CHEMBL152867 ZINC13449359 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762775 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.200000 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762777 CC(C)c1ccccc1N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 InChI=1S/C24H34N4O/c1-19(2)22-7-4-5-8-23(22)27-15-13-26(14-16-27)17-20-10-11-21(25(20)3)18-28-12-6-9-24(28)29/h4-5,7-8,10-11,19H,6,9,12-18H2,1-3H3 ARSYJYRZNBRPGH-UHFFFAOYSA-N 50001866 1-{5-[4-(2-Isopropyl-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL357286 D(2) dopamine receptor Rattus norvegicus 4.6 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724486 103916233 CHEMBL357286 ZINC13449333 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762780 COc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C23H32N4O2/c1-24-19(10-11-20(24)18-27-12-6-5-9-23(27)28)17-25-13-15-26(16-14-25)21-7-3-4-8-22(21)29-2/h3-4,7-8,10-11H,5-6,9,12-18H2,1-2H3 JRAIIPBUVORQLR-UHFFFAOYSA-N 50001881 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL152776 D(2) dopamine receptor Rattus norvegicus 9.5 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001881&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724501 103916248 CHEMBL152776 ZINC53230753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762782 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762785 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 7.8 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762787 Cn1c(CN2CCCC2=O)ccc1CN1CCN(CC1)c1ccccc1 InChI=1S/C21H28N4O/c1-22-19(9-10-20(22)17-25-11-5-8-21(25)26)16-23-12-14-24(15-13-23)18-6-3-2-4-7-18/h2-4,6-7,9-10H,5,8,11-17H2,1H3 HEKIAVJEIMRPAX-UHFFFAOYSA-N 50001890 1-[1-Methyl-5-(4-phenyl-piperazin-1-ylmethyl)-1H-pyrrol-2-ylmethyl]-pyrrolidin-2-one::CHEMBL346459 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724507 103916257 CHEMBL346459 ZINC13449323 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762791 CC(C)c1ccccc1N1CCN(Cc2ccc(CN3CCCCCC3=O)n2C)CC1 InChI=1S/C26H38N4O/c1-21(2)24-9-6-7-10-25(24)29-17-15-28(16-18-29)19-22-12-13-23(27(22)3)20-30-14-8-4-5-11-26(30)31/h6-7,9-10,12-13,21H,4-5,8,11,14-20H2,1-3H3 ITQRUODJAHLNPZ-UHFFFAOYSA-N 50001879 1-{5-[4-(2-Isopropyl-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-azepan-2-one::CHEMBL152458 D(2) dopamine receptor Rattus norvegicus 2.3 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001879&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724505 103916246 CHEMBL152458 ZINC13449384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762794 Cn1c(CN2CCCC2=O)ccc1CN1CCN(CC1)c1cccc(c1)[N+]([O-])=O InChI=1S/C21H27N5O3/c1-22-19(7-8-20(22)16-25-9-3-6-21(25)27)15-23-10-12-24(13-11-23)17-4-2-5-18(14-17)26(28)29/h2,4-5,7-8,14H,3,6,9-13,15-16H2,1H3 IWXPRWKKFNXNQW-UHFFFAOYSA-N 50001854 1-{1-Methyl-5-[4-(3-nitro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL153263 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724498 103916221 CHEMBL153263 ZINC13449374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762798 COc1cccc(c1)N1CCN(Cc2ccc(CN3CCCC3=O)n2C)CC1 InChI=1S/C22H30N4O2/c1-23-19(8-9-20(23)17-26-10-4-7-22(26)27)16-24-11-13-25(14-12-24)18-5-3-6-21(15-18)28-2/h3,5-6,8-9,15H,4,7,10-14,16-17H2,1-2H3 CDWACFHXMBNTNJ-UHFFFAOYSA-N 50001893 1-{5-[4-(3-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-pyrrolidin-2-one::CHEMBL153161 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001893&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15724499 103916260 CHEMBL153161 ZINC13449377 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762799 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 2.8 ChEMBL 10.1021/jm00081a018 10.7270/Q2PR7WMW 1346653 Scott, MK; Martin, GE; DiStefano, DL; Fedde, CL; Kukla, MJ; Barrett, DL; Baldy, WJ; Elgin, RJ; Kesslick, JM; Mathiasen, JR R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50744739 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 5340 ChEMBL 10.1021/jm00367a006 10.7270/Q21J9BBG 6317860 Dandridge, PA; Kaiser, C; Brenner, M; Gaitanopoulos, D; Davis, LD; Webb, RL; Foley, JJ; Sarau, HM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50744744 CN1CC(c2ccc(O)c(O)c2)c2cccc(N)c2C1 InChI=1S/C16H18N2O2/c1-18-8-12(10-5-6-15(19)16(20)7-10)11-3-2-4-14(17)13(11)9-18/h2-7,12,19-20H,8-9,17H2,1H3 ODIYTWXTFQEXKZ-UHFFFAOYSA-N 50027797 4-(8-Amino-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-yl)-benzene-1,2-diol::CHEMBL119555 D(2) dopamine receptor Rattus norvegicus 92000 ChEMBL 10.1021/jm00367a006 10.7270/Q21J9BBG 6317860 Dandridge, PA; Kaiser, C; Brenner, M; Gaitanopoulos, D; Davis, LD; Webb, RL; Foley, JJ; Sarau, HM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 194310 103937246 CHEMBL119555 ZINC27102844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50744745 CN1C[C@@H](c2ccc(O)c(O)c2)c2cccc(N)c2C1 InChI=1S/C16H18N2O2/c1-18-8-12(10-5-6-15(19)16(20)7-10)11-3-2-4-14(17)13(11)9-18/h2-7,12,19-20H,8-9,17H2,1H3/t12-/m0/s1 ODIYTWXTFQEXKZ-LBPRGKRZSA-N 50367174 CHEMBL1788237 D(2) dopamine receptor Rattus norvegicus 85800 ChEMBL 10.1021/jm00367a006 10.7270/Q21J9BBG 6317860 Dandridge, PA; Kaiser, C; Brenner, M; Gaitanopoulos, D; Davis, LD; Webb, RL; Foley, JJ; Sarau, HM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54580951 160846276 CHEMBL1788237 ZINC27102842 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750777 CN1CCN(CC1)[C@@H]1C[C@H](c2ccc(F)cc12)c1ccc(F)cc1 InChI=1S/C20H22F2N2/c1-23-8-10-24(11-9-23)20-13-18(14-2-4-15(21)5-3-14)17-7-6-16(22)12-19(17)20/h2-7,12,18,20H,8-11,13H2,1H3/t18-,20+/m0/s1 BOFPIRRSGDHUCZ-AZUAARDMSA-N 50020224 1-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-4-methyl-piperazine::CHEMBL70887 D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020224&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154764 103931138 CHEMBL70887 ZINC22937728 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750779 CCN1CCN(CCN2CCN(CC2)C2CC(c3ccc(F)cc23)c2ccc(F)cc2)C1=O InChI=1S/C26H32F2N4O/c1-2-30-15-16-32(26(30)33)14-11-29-9-12-31(13-10-29)25-18-23(19-3-5-20(27)6-4-19)22-8-7-21(28)17-24(22)25/h3-8,17,23,25H,2,9-16,18H2,1H3 NYGVMFLFMGJQCG-UHFFFAOYSA-N 50367650 CHEMBL1237323 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367650&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208353 160846752 CHEMBL1237323 ZINC26376386 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750780 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750781 Fc1ccc(cc1)[C@@H]1C[C@@H](N2CCN(CCN3CCNC3=O)CC2)c2cc(F)ccc12 InChI=1S/C24H28F2N4O/c25-18-3-1-17(2-4-18)21-16-23(22-15-19(26)5-6-20(21)22)29-12-9-28(10-13-29)11-14-30-8-7-27-24(30)31/h1-6,15,21,23H,7-14,16H2,(H,27,31)/t21-,23+/m0/s1 MYVPKBWFYFYMBK-JTHBVZDNSA-N 50367651 CHEMBL1237338 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208343 160846753 CHEMBL1237338 ZINC26376998 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750790 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCC3=O)CC2)c2cc(F)ccc12 InChI=1S/C25H29F2N3O/c26-19-5-3-18(4-6-19)22-17-24(23-16-20(27)7-8-21(22)23)29-13-10-28(11-14-29)12-15-30-9-1-2-25(30)31/h3-8,16,22,24H,1-2,9-15,17H2 GUAKGWYDXPBRKT-UHFFFAOYSA-N 50367655 CHEMBL1237343 D(2) dopamine receptor Rattus norvegicus 85 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367655&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208361 160846757 CHEMBL1237343 ZINC26382600 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750791 CN1CCN(CCN2CCN(CC2)C2CC(c3ccc(F)cc23)c2ccc(F)cc2)C1=O InChI=1S/C25H30F2N4O/c1-28-8-12-31(25(28)32)15-11-29-9-13-30(14-10-29)24-17-22(18-2-4-19(26)5-3-18)21-7-6-20(27)16-23(21)24/h2-7,16,22,24H,8-15,17H2,1H3 OJVLTRBLPKFAOC-UHFFFAOYSA-N 50367656 CHEMBL1237327 D(2) dopamine receptor Rattus norvegicus 260 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367656&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208350 160846758 CHEMBL1237327 ZINC26296475 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750792 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H29FN4O/c25-19-7-5-18(6-8-19)22-17-23(21-4-2-1-3-20(21)22)28-14-11-27(12-15-28)13-16-29-10-9-26-24(29)30/h1-8,22-23H,9-17H2,(H,26,30) GHAMYXPEZSUOCU-UHFFFAOYSA-N 50004310 1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL267795 D(2) dopamine receptor Rattus norvegicus 930 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004310&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10319293 103917993 CHEMBL267795 ZINC22463226 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750794 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCNC3=O)CC2)c2cc(F)ccc12 InChI=1S/C24H28F2N4O/c25-18-3-1-17(2-4-18)21-16-23(22-15-19(26)5-6-20(21)22)29-12-9-28(10-13-29)11-14-30-8-7-27-24(30)31/h1-6,15,21,23H,7-14,16H2,(H,27,31) MYVPKBWFYFYMBK-UHFFFAOYSA-N 50020231 1-(2-{4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL431786 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020231 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020231&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208342 103931145 CHEMBL431786 ZINC26382158 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750795 COc1ccc(cc1)C1CC(N2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C25H32N4O2/c1-31-20-8-6-19(7-9-20)23-18-24(22-5-3-2-4-21(22)23)28-15-12-27(13-16-28)14-17-29-11-10-26-25(29)30/h2-9,23-24H,10-18H2,1H3,(H,26,30) YJQDMAVDLRKARR-UHFFFAOYSA-N 50020237 1-(2-{4-[3-(4-Methoxy-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL306939 D(2) dopamine receptor Rattus norvegicus 15000 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020237&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208340 103931151 CHEMBL306939 ZINC26377473 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750803 Fc1ccc(cc1)[C@H]1C[C@H](N2CCN(CCN3CCNC3=O)CC2)c2cc(F)ccc12 InChI=1S/C24H28F2N4O/c25-18-3-1-17(2-4-18)21-16-23(22-15-19(26)5-6-20(21)22)29-12-9-28(10-13-29)11-14-30-8-7-27-24(30)31/h1-6,15,21,23H,7-14,16H2,(H,27,31)/t21-,23+/m1/s1 MYVPKBWFYFYMBK-GGAORHGYSA-N 50367657 CHEMBL1237328 D(2) dopamine receptor Rattus norvegicus 4500 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367657&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18609309 160846759 CHEMBL1237328 ZINC26375730 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750804 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) IENZQIKPVFGBNW-UHFFFAOYSA-N 29568 CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin D(2) dopamine receptor Rattus norvegicus 11000 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search XRA 3OWX 4893 81054997 8364 CHEMBL2 DB00457 503 C07368 ZINC00601304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750812 OCCN1CCN(CC1)C1CC(c2ccccc12)c1ccc(F)cc1 InChI=1S/C21H25FN2O/c22-17-7-5-16(6-8-17)20-15-21(19-4-2-1-3-18(19)20)24-11-9-23(10-12-24)13-14-25/h1-8,20-21,25H,9-15H2 IEIKIDQXGHFLJU-UHFFFAOYSA-N 50020243 (trans) 2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL308123 D(2) dopamine receptor Rattus norvegicus 680 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020243&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154791 103931157 CHEMBL308123 ZINC26383870 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750815 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 1800 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750816 CN1CCN(CC1)C1CC(c2ccc(F)cc12)c1ccc(F)cc1 InChI=1S/C20H22F2N2/c1-23-8-10-24(11-9-23)20-13-18(14-2-4-15(21)5-3-14)17-7-6-16(22)12-19(17)20/h2-7,12,18,20H,8-11,13H2,1H3 BOFPIRRSGDHUCZ-UHFFFAOYSA-N 50020240 1-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-4-methyl-piperazine::CHEMBL1204285::CHEMBL307717 D(2) dopamine receptor Rattus norvegicus 91 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154762 103931154 CHEMBL307717CHEMBL1204285 ZINC22937739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750819 Fc1ccc(cc1)C1CC(N2CCN(CCCN3CCOC3=O)CC2)c2cc(F)ccc12 InChI=1S/C25H29F2N3O2/c26-19-4-2-18(3-5-19)22-17-24(23-16-20(27)6-7-21(22)23)29-12-10-28(11-13-29)8-1-9-30-14-15-32-25(30)31/h2-7,16,22,24H,1,8-15,17H2 QXTIGKAEHWCSKP-UHFFFAOYSA-N 50367658 CHEMBL1237333 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367658&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208367 160846760 CHEMBL1237333 ZINC26378154 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752372 CN1CCN(CC1)C1=Nc2ccccc2Nc2c1cnn2C InChI=1S/C16H20N6/c1-20-7-9-22(10-8-20)16-12-11-17-21(2)15(12)18-13-5-3-4-6-14(13)19-16/h3-6,11,18H,7-10H2,1-2H3 AYLIXQQLAHPDDJ-UHFFFAOYSA-N 50017642 3-Methyl-10-(4-methyl-piperazin-1-yl)-3,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL433339 D(2) dopamine receptor Rattus norvegicus 1500000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590624 103928910 CHEMBL433339 ZINC26575959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752373 Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCCCC2)n1 InChI=1S/C16H18FN5/c1-21-10-12-15(20-21)18-13-6-5-11(17)9-14(13)19-16(12)22-7-3-2-4-8-22/h5-6,9-10H,2-4,7-8H2,1H3,(H,18,20) NMNHCPZKHZJVQE-UHFFFAOYSA-N 50017639 7-Fluoro-2-methyl-10-piperidin-1-yl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL313303 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017639&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590631 103928907 CHEMBL313303 ZINC26575612 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752374 Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCNCC2)n1 InChI=1S/C15H17FN6/c1-21-9-11-14(20-21)18-12-3-2-10(16)8-13(12)19-15(11)22-6-4-17-5-7-22/h2-3,8-9,17H,4-7H2,1H3,(H,18,20) AATNUAIEJXUQIC-UHFFFAOYSA-N 50017640 7-Fluoro-2-methyl-10-piperazin-1-yl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL314226 D(2) dopamine receptor Rattus norvegicus 5200 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017640&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590627 103928908 CHEMBL314226 ZINC26576960 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752375 CN1CCN(CC1)C1=Nc2ccccc2Nc2nn(C)cc12 InChI=1S/C16H20N6/c1-20-7-9-22(10-8-20)16-12-11-21(2)19-15(12)17-13-5-3-4-6-14(13)18-16/h3-6,11H,7-10H2,1-2H3,(H,17,19) JRCCQSATNATUEI-UHFFFAOYSA-N 50017618 2-Methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL313725 D(2) dopamine receptor Rattus norvegicus 6300 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888794 103928886 CHEMBL313725 ZINC26573925 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752376 CN1CCN(CC1)C1=Nc2cc(ccc2Nc2nn(C)cc12)S(C)(=O)=O InChI=1S/C17H22N6O2S/c1-21-6-8-23(9-7-21)17-13-11-22(2)20-16(13)18-14-5-4-12(26(3,24)25)10-15(14)19-17/h4-5,10-11H,6-9H2,1-3H3,(H,18,20) DLKZVJLBWAZZQG-UHFFFAOYSA-N 50017652 7-Methanesulfonyl-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL315120 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017652&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590621 103928920 CHEMBL315120 ZINC26576074 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752377 CN1CCN(CC1)C1=Nc2cc(I)ccc2Nc2nn(C)cc12 InChI=1S/C16H19IN6/c1-21-5-7-23(8-6-21)16-12-10-22(2)20-15(12)18-13-4-3-11(17)9-14(13)19-16/h3-4,9-10H,5-8H2,1-2H3,(H,18,20) AWTFPRSUYNRMKT-UHFFFAOYSA-N 50017653 7-Iodo-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL87382 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017653&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888793 103928921 CHEMBL87382 ZINC26576075 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752378 Cn1cc2c(Nc3ccc(F)cc3N=C2N2CCN(Cc3ccccc3)CC2)n1 InChI=1S/C22H23FN6/c1-27-15-18-21(26-27)24-19-8-7-17(23)13-20(19)25-22(18)29-11-9-28(10-12-29)14-16-5-3-2-4-6-16/h2-8,13,15H,9-12,14H2,1H3,(H,24,26) UQXLCQQSDUCPFW-UHFFFAOYSA-N 50017651 10-(4-Benzyl-piperazin-1-yl)-7-fluoro-2-methyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL86469 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888802 103928919 CHEMBL86469 ZINC26576377 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752379 CN1CCN(CC1)C1=Nc2ccc(Cl)cc2Nc2nn(C)cc12 InChI=1S/C16H19ClN6/c1-21-5-7-23(8-6-21)16-12-10-22(2)20-15(12)18-14-9-11(17)3-4-13(14)19-16/h3-4,9-10H,5-8H2,1-2H3,(H,18,20) UUAXKAADUPQBHB-UHFFFAOYSA-N 50017629 6-Chloro-2-methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulene::CHEMBL315052 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017629&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12888810 103928897 CHEMBL315052 ZINC26574232 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752380 CN1CCN(CC1)C1=Nc2cc(ccc2Nc2nn(C)cc12)C(=O)c1ccccc1 InChI=1S/C23H24N6O/c1-27-10-12-29(13-11-27)23-18-15-28(2)26-22(18)24-19-9-8-17(14-20(19)25-23)21(30)16-6-4-3-5-7-16/h3-9,14-15H,10-13H2,1-2H3,(H,24,26) OMOZQLYRYVWXEX-UHFFFAOYSA-N 50017625 CHEMBL262164::[2-Methyl-10-(4-methyl-piperazin-1-yl)-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulen-7-yl]-phenyl-methanone D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017625&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590620 103928893 CHEMBL262164 ZINC26576419 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752381 CN(C)CCNC1=Nc2cc(F)ccc2Nc2nn(C)cc12 InChI=1S/C15H19FN6/c1-21(2)7-6-17-14-11-9-22(3)20-15(11)18-12-5-4-10(16)8-13(12)19-14/h4-5,8-9H,6-7H2,1-3H3,(H,17,19)(H,18,20) ZSDYXKFZRXFLBU-UHFFFAOYSA-N 50017620 CHEMBL86342::N'-(7-Fluoro-2-methyl-2,4-dihydro-2,3,4,9-tetraaza-benzo[f]azulen-10-yl)-N,N-dimethyl-ethane-1,2-diamine D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00132a012 10.7270/Q22F7P2J 2573732 Chakrabarti, JK; Hotten, TM; Pullar, IA; Type, NC Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017620&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14590630 103928888 CHEMBL86342 ZINC26576878 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756597 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus 6865 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756600 NC[C@@H]1O[C@@H](Cc2c(O)c(Br)ccc12)c1ccccc1 InChI=1S/C16H16BrNO2/c17-13-7-6-11-12(16(13)19)8-14(20-15(11)9-18)10-4-2-1-3-5-10/h1-7,14-15,19H,8-9,18H2/t14-,15-/m0/s1 SIPQEKQXLUBVAY-GJZGRUSLSA-N 50008824 1-Aminomethyl-6-bromo-3-phenyl-isochroman-5-ol; hydrochloride::CHEMBL543390 D(2) dopamine receptor Rattus norvegicus 569 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008824&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15711869 103921935 CHEMBL543390 ZINC13824664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756602 CN(C)C[C@@H]1O[C@@H](Cc2c(O)c(C)ccc12)C1CCCCC1 InChI=1S/C19H29NO2/c1-13-9-10-15-16(19(13)21)11-17(14-7-5-4-6-8-14)22-18(15)12-20(2)3/h9-10,14,17-18,21H,4-8,11-12H2,1-3H3/t17-,18-/m0/s1 XJAIZZAVIKJXAV-ROUUACIJSA-N 50008827 3-Cyclohexyl-1-dimethylaminomethyl-6-methyl-isochroman-5-ol; hydrochloride::CHEMBL545264 D(2) dopamine receptor Rattus norvegicus 18000 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008827&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15711851 103921938 CHEMBL545264 ZINC13824654 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756603 NC[C@@H]1O[C@@H](Cc2c(O)cccc12)c1ccccc1 InChI=1S/C16H17NO2/c17-10-16-12-7-4-8-14(18)13(12)9-15(19-16)11-5-2-1-3-6-11/h1-8,15-16,18H,9-10,17H2/t15-,16-/m0/s1 UYGVYUSBNCJHOS-HOTGVXAUSA-N 50008828 1-Aminomethyl-3-phenyl-isochroman-5-ol; hydrochloride::CHEMBL541838 D(2) dopamine receptor Rattus norvegicus >30000 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008828&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15711865 103921939 CHEMBL541838 ZINC13824662 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756605 NC[C@H]1O[C@@H](Cc2c(O)c(Br)ccc12)c1ccccc1 InChI=1S/C16H16BrNO2/c17-13-7-6-11-12(16(13)19)8-14(20-15(11)9-18)10-4-2-1-3-5-10/h1-7,14-15,19H,8-9,18H2/t14-,15+/m0/s1 SIPQEKQXLUBVAY-LSDHHAIUSA-N 50008829 1-Aminomethyl-6-bromo-3-phenyl-isochroman-5-ol; hydrochloride::CHEMBL538520 D(2) dopamine receptor Rattus norvegicus 1960 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008829&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15711870 103921940 CHEMBL538520 ZINC13824666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756608 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 886 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756612 CNC[C@@H]1O[C@@H](Cc2c(O)c(C)ccc12)C1CCCCC1 InChI=1S/C18H27NO2/c1-12-8-9-14-15(18(12)20)10-16(21-17(14)11-19-2)13-6-4-3-5-7-13/h8-9,13,16-17,19-20H,3-7,10-11H2,1-2H3/t16-,17-/m0/s1 TWJRNAUVADBAOE-IRXDYDNUSA-N 50008831 3-Cyclohexyl-6-methyl-1-methylaminomethyl-isochroman-5-ol; hydrobromide::CHEMBL544099 D(2) dopamine receptor Rattus norvegicus 4610 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008831&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15711855 103921942 CHEMBL544099 ZINC13824658 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756622 COc1ccc2[C@H](CN)O[C@@H](Cc2c1O)c1ccccc1 InChI=1S/C17H19NO3/c1-20-14-8-7-12-13(17(14)19)9-15(21-16(12)10-18)11-5-3-2-4-6-11/h2-8,15-16,19H,9-10,18H2,1H3/t15-,16-/m0/s1 CJSINCRQHDFMNW-HOTGVXAUSA-N 50008830 1-Aminomethyl-6-methoxy-3-phenyl-isochroman-5-ol; hydrochloride::CHEMBL555619 D(2) dopamine receptor Rattus norvegicus >30000 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008830&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15711860 103921941 CHEMBL555619 ZINC13824660 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756625 Cc1ccc2[C@H](CN)O[C@@H](Cc2c1O)C1CCCCC1 InChI=1S/C17H25NO2/c1-11-7-8-13-14(17(11)19)9-15(20-16(13)10-18)12-5-3-2-4-6-12/h7-8,12,15-16,19H,2-6,9-10,18H2,1H3/t15-,16-/m0/s1 HSJYTPFWWPUYDT-HOTGVXAUSA-N 50008825 1-Aminomethyl-3-cyclohexyl-6-methyl-isochroman-5-ol; hydrobromide::CHEMBL542436 D(2) dopamine receptor Rattus norvegicus >30000 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008825&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15711850 103921936 CHEMBL542436 ZINC13824652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756629 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1 SUHGRZPINGKYNV-GJZGRUSLSA-N 50007129 (1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol::1-Aminomethyl-3-phenyl-isochroman-5,6-diol::A-70108::CHEMBL86931 D(2) dopamine receptor Rattus norvegicus 776 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122324 103920412 CHEMBL86931 6077 ZINC03787668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756631 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C16H23NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h6-7,10,14-15,18-19H,1-5,8-9,17H2/t14-,15-/m0/s1 BOKASTZDGGZFET-GJZGRUSLSA-N 50008832 1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol::CHEMBL100572 D(2) dopamine receptor Rattus norvegicus 1120 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008832&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15696466 103921943 CHEMBL100572 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50756637 CCCNC[C@@H]1O[C@@H](Cc2c(O)c(C)ccc12)C1CCCCC1 InChI=1S/C20H31NO2/c1-3-11-21-13-19-16-10-9-14(2)20(22)17(16)12-18(23-19)15-7-5-4-6-8-15/h9-10,15,18-19,21-22H,3-8,11-13H2,1-2H3/t18-,19-/m0/s1 HNIPUZVIZRFWRR-OALUTQOASA-N 50008826 3-Cyclohexyl-6-methyl-1-propylaminomethyl-isochroman-5-ol; hydrochloride::CHEMBL543389 D(2) dopamine receptor Rattus norvegicus 2630 ChEMBL 10.1021/jm00114a002 10.7270/Q2H132MN 1833546 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008826&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15711852 103921937 CHEMBL543389 ZINC13824656 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758485 O=C1N(CCCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23 InChI=1S/C25H24N2O/c28-25-22-11-4-9-21-10-5-12-23(24(21)22)27(25)16-6-15-26-17-13-20(14-18-26)19-7-2-1-3-8-19/h1-5,7-13H,6,14-18H2 RWOFMBJYEBXDKZ-UHFFFAOYSA-N 50010032 1-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-1H-benzo[cd]indol-2-one::CHEMBL442185 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710742 103922960 CHEMBL442185 ZINC13823450 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758486 Cc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C24H27N3O2S/c1-19-9-11-21(12-10-19)26-17-15-25(16-18-26)13-4-14-27-22-7-2-5-20-6-3-8-23(24(20)22)30(27,28)29/h2-3,5-12H,4,13-18H2,1H3 OFDXTWFEOOKPAV-UHFFFAOYSA-N 50010034 2-[3-(4-p-Tolyl-piperazin-1-yl)-propyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL84465 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710731 103922962 CHEMBL84465 ZINC13823490 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758489 Fc1cccc(c1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24FN3O2S/c24-19-7-3-8-20(17-19)26-15-13-25(14-16-26)11-4-12-27-21-9-1-5-18-6-2-10-22(23(18)21)30(27,28)29/h1-3,5-10,17H,4,11-16H2 GZVYNCBPEHDVIB-UHFFFAOYSA-N 50010039 2-{3-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL415272 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710729 103922967 CHEMBL415272 ZINC13823482 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758491 O=S1(=O)N(CCCN2CCN(CC2)c2nsc3ccccc23)c2cccc3cccc1c23 InChI=1S/C24H24N4O2S2/c29-32(30)22-11-4-7-18-6-3-9-20(23(18)22)28(32)13-5-12-26-14-16-27(17-15-26)24-19-8-1-2-10-21(19)31-25-24/h1-4,6-11H,5,12-17H2 PADNXJNFCDTGTC-UHFFFAOYSA-N 50010038 2-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-propyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL79927 D(2) dopamine receptor Rattus norvegicus 473 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010038&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710737 103922966 CHEMBL79927 ZINC13823474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758494 Brc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24BrN3O2S/c24-19-8-10-20(11-9-19)26-16-14-25(15-17-26)12-3-13-27-21-6-1-4-18-5-2-7-22(23(18)21)30(27,28)29/h1-2,4-11H,3,12-17H2 LGLMUFXNPSGLCJ-UHFFFAOYSA-N 50010045 2-{3-[4-(4-Bromo-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL83780 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580038 103922973 CHEMBL83780 ZINC13823486 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758495 Fc1ccccc1N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24FN3O2S/c24-19-8-1-2-9-20(19)26-16-14-25(15-17-26)12-5-13-27-21-10-3-6-18-7-4-11-22(23(18)21)30(27,28)29/h1-4,6-11H,5,12-17H2 RYQFNVDIVFBVPT-UHFFFAOYSA-N 50010047 2-{3-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL83975 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710728 103922975 CHEMBL83975 ZINC13823480 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758496 O=S1(=O)N(CCCN2CCN(CC2)c2noc3ccccc23)c2cccc3cccc1c23 InChI=1S/C24H24N4O3S/c29-32(30)22-11-4-7-18-6-3-9-20(23(18)22)28(32)13-5-12-26-14-16-27(17-15-26)24-19-8-1-2-10-21(19)31-25-24/h1-4,6-11H,5,12-17H2 DAWLQXVXJZJFFV-UHFFFAOYSA-N 50010033 2-[3-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-propyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL418911 D(2) dopamine receptor Rattus norvegicus 990 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710736 103922961 CHEMBL418911 ZINC12356437 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758497 O=S1(=O)N(CCCN2CCN(CC2)c2nc3ccccc3s2)c2cccc3cccc1c23 InChI=1S/C24H24N4O2S2/c29-32(30)22-11-4-7-18-6-3-9-20(23(18)22)28(32)13-5-12-26-14-16-27(17-15-26)24-25-19-8-1-2-10-21(19)31-24/h1-4,6-11H,5,12-17H2 AADXJQSANSVKFN-UHFFFAOYSA-N 50010046 2-[3-(4-Benzothiazol-2-yl-piperazin-1-yl)-propyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL83391 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710739 103922974 CHEMBL83391 ZINC13823478 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758499 O=S1(=O)N(CCCN2CCC(=CC2)c2ccccc2)c2ccccc2-c2ccccc12 InChI=1S/C26H26N2O2S/c29-31(30)26-14-7-5-12-24(26)23-11-4-6-13-25(23)28(31)18-8-17-27-19-15-22(16-20-27)21-9-2-1-3-10-21/h1-7,9-15H,8,16-20H2 CUSNRDWDRXFUFH-UHFFFAOYSA-N 50010036 10-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-10H-9-thia-10-aza-phenanthrene 9,9-dioxide::CHEMBL83664 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010036&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710746 103922964 CHEMBL83664 ZINC13823459 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758503 [O-][N+](=O)c1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24N4O4S/c28-27(29)20-10-8-19(9-11-20)25-16-14-24(15-17-25)12-3-13-26-21-6-1-4-18-5-2-7-22(23(18)21)32(26,30)31/h1-2,4-11H,3,12-17H2 MPUZMWHQBSJEPZ-UHFFFAOYSA-N 50010053 2-{3-[4-(4-Nitro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL84077 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710733 103922981 CHEMBL84077 ZINC13823494 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758505 O=c1[nH]c2ccccc2n1C1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C25H26N4O3S/c30-25-26-20-8-1-2-9-21(20)29(25)19-12-16-27(17-13-19)14-5-15-28-22-10-3-6-18-7-4-11-23(24(18)22)33(28,31)32/h1-4,6-11,19H,5,12-17H2,(H,26,30) ZXYZYKRBNAHRIG-UHFFFAOYSA-N 50010054 1-{1-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]isothiazol-2-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL81813 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010054&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710727 103922982 CHEMBL81813 ZINC13823468 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758506 Fc1ccc(cc1)C(=C1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1)c1ccc(F)cc1 InChI=1S/C31H28F2N2O2S/c32-26-12-8-23(9-13-26)30(24-10-14-27(33)15-11-24)25-16-20-34(21-17-25)18-3-19-35-28-6-1-4-22-5-2-7-29(31(22)28)38(35,36)37/h1-2,4-15H,3,16-21H2 DMYVDWKBRXSJBY-UHFFFAOYSA-N 50010031 2-(3-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-propyl)-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL84346 D(2) dopamine receptor Rattus norvegicus 603 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710726 103922959 CHEMBL84346 ZINC26500006 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758507 O=S1(=O)N(CCCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23 InChI=1S/C24H24N2O2S/c27-29(28)23-12-5-10-21-9-4-11-22(24(21)23)26(29)16-6-15-25-17-13-20(14-18-25)19-7-2-1-3-8-19/h1-5,7-13H,6,14-18H2 OTKMWMJOFBUWDJ-UHFFFAOYSA-N 50010040 2-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL83787 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010040&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580027 103922968 CHEMBL83787 ZINC13823448 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758510 O=S1(=O)N(CCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23 InChI=1S/C23H22N2O2S/c26-28(27)22-11-5-9-20-8-4-10-21(23(20)22)25(28)17-16-24-14-12-19(13-15-24)18-6-2-1-3-7-18/h1-12H,13-17H2 GGWHOXVBCOIHCB-UHFFFAOYSA-N 50010043 2-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL310105 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580042 103922971 CHEMBL310105 ZINC13823498 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758511 Fc1ccc(cc1)C(=O)C1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C25H25FN2O3S/c26-21-10-8-19(9-11-21)25(29)20-12-16-27(17-13-20)14-3-15-28-22-6-1-4-18-5-2-7-23(24(18)22)32(28,30)31/h1-2,4-11,20H,3,12-17H2 YGCLJBSIKQLHLJ-UHFFFAOYSA-N 50010041 CHEMBL84087::{1-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]isothiazol-2-yl)-propyl]-piperidin-4-yl}-(4-fluoro-phenyl)-methanone D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010041&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580035 103922969 CHEMBL84087 ZINC13823466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758513 O=S1(=O)N(CCCN2CCN(CC2)c2ccccc2)c2cccc3cccc1c23 InChI=1S/C23H25N3O2S/c27-29(28)22-12-5-8-19-7-4-11-21(23(19)22)26(29)14-6-13-24-15-17-25(18-16-24)20-9-2-1-3-10-20/h1-5,7-12H,6,13-18H2 AWSBXOYZYNLCBZ-UHFFFAOYSA-N 50010057 2-[3-(4-Phenyl-piperazin-1-yl)-propyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL82651 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010057&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580032 103922985 CHEMBL82651 ZINC13823461 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758515 O=S1(=O)N(CCCN2CCN(CC2)c2ncccn2)c2cccc3cccc1c23 InChI=1S/C21H23N5O2S/c27-29(28)19-8-2-6-17-5-1-7-18(20(17)19)26(29)12-4-11-24-13-15-25(16-14-24)21-22-9-3-10-23-21/h1-3,5-10H,4,11-16H2 YTJUGWSTNZLRMM-UHFFFAOYSA-N 50010060 2-[3-(4-Pyrimidin-2-yl-piperazin-1-yl)-propyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL312043 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010060&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710735 103922988 CHEMBL312043 ZINC13823472 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758521 O=S1(=O)N=C(N2CCN(CCCN3c4cccc5cccc(c45)S3(=O)=O)CC2)c2ccccc12 InChI=1S/C24H24N4O4S2/c29-33(30)21-10-2-1-8-19(21)24(25-33)27-16-14-26(15-17-27)12-5-13-28-20-9-3-6-18-7-4-11-22(23(18)20)34(28,31)32/h1-4,6-11H,5,12-17H2 UVCMETSMBWPLJK-UHFFFAOYSA-N 50010059 2-{3-[4-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL309408 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010059&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710738 103922987 CHEMBL309408 ZINC13823476 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758522 O=S1(=O)N(CCCN2CCN(CC2)c2ccccn2)c2cccc3cccc1c23 InChI=1S/C22H24N4O2S/c27-29(28)20-9-4-7-18-6-3-8-19(22(18)20)26(29)13-5-12-24-14-16-25(17-15-24)21-10-1-2-11-23-21/h1-4,6-11H,5,12-17H2 WZPVCQCUVPNFAG-UHFFFAOYSA-N 50010055 2-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL316227 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010055&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580031 103922983 CHEMBL316227 ZINC13823470 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758524 CS(=O)(=O)N(CCCN1CCC(=CC1)c1ccccc1)c1cccc2ccccc12 InChI=1S/C25H28N2O2S/c1-30(28,29)27(25-14-7-12-23-11-5-6-13-24(23)25)18-8-17-26-19-15-22(16-20-26)21-9-3-2-4-10-21/h2-7,9-15H,8,16-20H2,1H3 SCPNMTOXHVHEIH-UHFFFAOYSA-N 50010037 CHEMBL79598::N-Naphthalen-1-yl-N-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 275 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010037&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710743 103922965 CHEMBL79598 ZINC13823452 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758529 O=S1(=O)N(CCCCN2CCC(=CC2)c2ccccc2)c2cccc3cccc1c23 InChI=1S/C25H26N2O2S/c28-30(29)24-13-7-11-22-10-6-12-23(25(22)24)27(30)17-5-4-16-26-18-14-21(15-19-26)20-8-2-1-3-9-20/h1-3,6-14H,4-5,15-19H2 OKJRBFNMYSRTKZ-UHFFFAOYSA-N 50010052 2-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL440134 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710725 103922980 CHEMBL440134 ZINC13823500 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758532 Oc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H25N3O3S/c27-20-10-8-19(9-11-20)25-16-14-24(15-17-25)12-3-13-26-21-6-1-4-18-5-2-7-22(23(18)21)30(26,28)29/h1-2,4-11,27H,3,12-17H2 ZXCVMKUETOQIIM-UHFFFAOYSA-N 50010049 4-{4-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]isothiazol-2-yl)-propyl]-piperazin-1-yl}-phenol::CHEMBL79375 D(2) dopamine receptor Rattus norvegicus 508 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580034 103922977 CHEMBL79375 ZINC12356349 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758533 CCOC(=O)c1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C26H29N3O4S/c1-2-33-26(30)21-10-12-22(13-11-21)28-18-16-27(17-19-28)14-5-15-29-23-8-3-6-20-7-4-9-24(25(20)23)34(29,31)32/h3-4,6-13H,2,5,14-19H2,1H3 CYNNLBPFJCKOKG-UHFFFAOYSA-N 50010030 4-{4-[3-(1,1-Dioxo-1H-1lambda*6*-naphtho[1,8-cd]isothiazol-2-yl)-propyl]-piperazin-1-yl}-benzoic acid ethyl ester::CHEMBL311550 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010030&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710734 103922958 CHEMBL311550 ZINC13823496 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758535 Clc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24ClN3O2S/c24-19-8-10-20(11-9-19)26-16-14-25(15-17-26)12-3-13-27-21-6-1-4-18-5-2-7-22(23(18)21)30(27,28)29/h1-2,4-11H,3,12-17H2 CJJCHMQYAVQPOO-UHFFFAOYSA-N 50010042 2-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL83035 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010042&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580036 103922970 CHEMBL83035 ZINC13823484 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758536 O=S1(=O)N(CCCN2CCC(CC2)c2ccccc2)c2cccc3cccc1c23 InChI=1S/C24H26N2O2S/c27-29(28)23-12-5-10-21-9-4-11-22(24(21)23)26(29)16-6-15-25-17-13-20(14-18-25)19-7-2-1-3-8-19/h1-5,7-12,20H,6,13-18H2 IMZYYYXDGIFJFD-UHFFFAOYSA-N 50010048 2-[3-(4-Phenyl-piperidin-1-yl)-propyl]-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL418929 D(2) dopamine receptor Rattus norvegicus 385 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580033 103922976 CHEMBL418929 ZINC13823463 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758539 Fc1ccc(cc1)N1CCN(CCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C24H26FN3O2S/c25-20-9-11-21(12-10-20)27-17-15-26(16-18-27)13-1-2-14-28-22-7-3-5-19-6-4-8-23(24(19)22)31(28,29)30/h3-12H,1-2,13-18H2 ZRCNTFMWQUJZCU-UHFFFAOYSA-N 50010061 2-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL82826 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010061&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710741 103922989 CHEMBL82826 ZINC13823504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758540 FC(F)(F)c1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C24H24F3N3O2S/c25-24(26,27)19-8-10-20(11-9-19)29-16-14-28(15-17-29)12-3-13-30-21-6-1-4-18-5-2-7-22(23(18)21)33(30,31)32/h1-2,4-11H,3,12-17H2 QLNUIKIYAAUUBG-UHFFFAOYSA-N 50010035 2-{3-[4-(4-Trifluoromethyl-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL82167 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710732 103922963 CHEMBL82167 ZINC13823492 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758544 COc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C24H27N3O3S/c1-30-21-11-9-20(10-12-21)26-17-15-25(16-18-26)13-4-14-27-22-7-2-5-19-6-3-8-23(24(19)22)31(27,28)29/h2-3,5-12H,4,13-18H2,1H3 OUEYTZFYYVEBDH-UHFFFAOYSA-N 50010051 2-{3-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL79420 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710730 103922979 CHEMBL79420 ZINC13823488 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758555 O=S(=O)(N(CCCN1CCC(=CC1)c1ccccc1)c1ccccc1)c1ccccc1 InChI=1S/C26H28N2O2S/c29-31(30,26-15-8-3-9-16-26)28(25-13-6-2-7-14-25)20-10-19-27-21-17-24(18-22-27)23-11-4-1-5-12-23/h1-9,11-17H,10,18-22H2 QWVPSLXKIGGBPP-UHFFFAOYSA-N 50010050 CHEMBL309660::N-Phenyl-N-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-benzenesulfonamide D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710745 103922978 CHEMBL309660 ZINC13823454 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747171 C1CN(CCN1)C1SNc2ccccc12 InChI=1S/C11H15N3S/c1-2-4-10-9(3-1)11(15-13-10)14-7-5-12-6-8-14/h1-4,11-13H,5-8H2 AUISSLCYULMZPT-UHFFFAOYSA-N 50367312 CHEMBL1203223 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367312&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44347592 160846414 CHEMBL1203223 ZINC27197979 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747172 CSc1ccc2Sc3ccccc3N(CCC3CCCCN3C)c2c1 InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 KLBQZWRITKRQQV-UHFFFAOYSA-N 50002338 (Thioridazine)10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-(2-(1-methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine::10-[2-(1-Methyl-piperidin-2-yl)-ethyl]-2-methylsulfanyl-10H-phenothiazine (thioridazine)::CHEMBL479::MELLARIL::MELLARIL-S::THIORIDAZINE::TP-21::US9504692, Thioridazine D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LZU 4I1R,4UHX 5452 103916644 9566 CHEMBL479 DB00679 100 ZINC01530697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747175 OC(CCCN1CCN(CC1)c1nsc2ccccc12)c1ccc(F)cc1 InChI=1S/C21H24FN3OS/c22-17-9-7-16(8-10-17)19(26)5-3-11-24-12-14-25(15-13-24)21-18-4-1-2-6-20(18)27-23-21/h1-2,4,6-10,19,26H,3,5,11-15H2 UIHHLYXRHNSTAF-UHFFFAOYSA-N 50019359 4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-1-(4-fluoro-phenyl)-butan-1-ol::CHEMBL123338 D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019359&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232486 103930328 CHEMBL123338 ZINC27196513 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747176 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747180 CCCC1(C)CC(=O)N(CCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)C1 InChI=1S/C24H34N4O2S/c1-3-10-24(2)17-21(29)28(22(30)18-24)12-7-6-11-26-13-15-27(16-14-26)23-19-8-4-5-9-20(19)31-25-23/h4-5,8-9H,3,6-7,10-18H2,1-2H3 AYTRJXMMVKNXDR-UHFFFAOYSA-N 50367314 CHEMBL1203224 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232491 160846416 CHEMBL1203224 ZINC27193271 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747181 O=C1SC2(CCCC2)C(=O)N1CCCCN1CCCN(CC1)c1noc2ccccc12 InChI=1S/C23H30N4O3S/c28-21-23(10-3-4-11-23)31-22(29)27(21)15-6-5-12-25-13-7-14-26(17-16-25)20-18-8-1-2-9-19(18)30-24-20/h1-2,8-9H,3-7,10-17H2 FOWNWEAIIITWBW-UHFFFAOYSA-N 50019364 3-[4-(4-Benzo[d]isoxazol-3-yl-[1,4]diazepan-1-yl)-butyl]-1-thia-3-aza-spiro[4.4]nonane-2,4-dione::CHEMBL123834 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019364 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019364&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13568464 103930333 CHEMBL123834 ZINC27197548 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747182 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 440 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747183 O=C1CSC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C18H22N4O2S2/c23-16-13-25-18(24)22(16)8-4-3-7-20-9-11-21(12-10-20)17-14-5-1-2-6-15(14)26-19-17/h1-2,5-6H,3-4,7-13H2 PIMLORHKUTTYEA-UHFFFAOYSA-N 50367315 CHEMBL1203220 D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367315&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232479 160846417 CHEMBL1203220 ZINC27196037 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750822 Fc1ccc(cc1)C1CC(N2CCN(CCCN3CCNC3=O)CC2)c2cc(F)ccc12 InChI=1S/C25H30F2N4O/c26-19-4-2-18(3-5-19)22-17-24(23-16-20(27)6-7-21(22)23)30-14-12-29(13-15-30)9-1-10-31-11-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) UIKUTSSOIQGDCL-UHFFFAOYSA-N 50367661 CHEMBL1237339 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367661&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208365 160846763 CHEMBL1237339 ZINC26376663 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750830 Fc1ccc(cc1)C1CC(N2CCN(CCn3c(=O)[nH]c4ccccc4c3=O)CC2)c2ccccc12 InChI=1S/C29H29FN4O2/c30-21-11-9-20(10-12-21)25-19-27(23-6-2-1-5-22(23)25)33-16-13-32(14-17-33)15-18-34-28(35)24-7-3-4-8-26(24)31-29(34)36/h1-12,25,27H,13-19H2,(H,31,36) XJMYQSULBMVILP-UHFFFAOYSA-N 50367652 CHEMBL1237330 D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367652&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208374 160846754 CHEMBL1237330 ZINC26375923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750831 Fc1ccc(cc1)C1CC(N2CCN(CCn3c(=O)[nH]c4ccccc4c3=O)CC2)c2cc(F)ccc12 InChI=1S/C29H28F2N4O2/c30-20-7-5-19(6-8-20)24-18-27(25-17-21(31)9-10-22(24)25)34-14-11-33(12-15-34)13-16-35-28(36)23-3-1-2-4-26(23)32-29(35)37/h1-10,17,24,27H,11-16,18H2,(H,32,37) AUDLXWKLEAZHMP-UHFFFAOYSA-N 50367663 CHEMBL1237325 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367663&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208373 160846765 CHEMBL1237325 ZINC26377348 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750835 Fc1ccc(cc1)[C@@H]1C[C@@H](N2CCN(CCN3CCNC3=S)CC2)c2cc(F)ccc12 InChI=1S/C24H28F2N4S/c25-18-3-1-17(2-4-18)21-16-23(22-15-19(26)5-6-20(21)22)29-12-9-28(10-13-29)11-14-30-8-7-27-24(30)31/h1-6,15,21,23H,7-14,16H2,(H,27,31)/t21-,23+/m0/s1 HLRUIZCWWSCWOZ-JTHBVZDNSA-N 50367662 CHEMBL1237320 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367662&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208328 160846764 CHEMBL1237320 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750838 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3ccc(F)cc23)c2ccc(F)cc2)C1=O InChI=1S/C27H34F2N4O/c1-19(2)33-16-15-32(27(33)34)14-11-30-9-12-31(13-10-30)26-18-24(20-3-5-21(28)6-4-20)23-8-7-22(29)17-25(23)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3 SWWJOJRZBIXCNX-UHFFFAOYSA-N 50367666 CHEMBL1237324 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367666&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208355 160846768 CHEMBL1237324 ZINC26295887 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750840 Fc1ccc(cc1)C1CC(N2CCNCC2)c2ccccc12 InChI=1S/C19H21FN2/c20-15-7-5-14(6-8-15)18-13-19(22-11-9-21-10-12-22)17-4-2-1-3-16(17)18/h1-8,18-19,21H,9-13H2 IEXNAGAJXPUXLE-UHFFFAOYSA-N 50020254 1-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazine::CHEMBL76004 D(2) dopamine receptor Rattus norvegicus 1900 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208318 103931168 CHEMBL76004 ZINC26383879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750843 Fc1ccc(cc1)C1CC(N2CCN(CCn3c4ccccc4[nH]c3=O)CC2)c2cc(F)ccc12 InChI=1S/C28H28F2N4O/c29-20-7-5-19(6-8-20)23-18-27(24-17-21(30)9-10-22(23)24)33-14-11-32(12-15-33)13-16-34-26-4-2-1-3-25(26)31-28(34)35/h1-10,17,23,27H,11-16,18H2,(H,31,35) DYLJDEUIZSKBJX-UHFFFAOYSA-N 50367668 CHEMBL1237331 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367668&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208371 160846770 CHEMBL1237331 ZINC26379130 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750848 O=C(N1CCN(CCN2CCNC2=O)CC1)c1ccccc1 InChI=1S/C16H22N4O2/c21-15(14-4-2-1-3-5-14)19-11-8-18(9-12-19)10-13-20-7-6-17-16(20)22/h1-5H,6-13H2,(H,17,22) ICPKTAVYZBVYRF-UHFFFAOYSA-N 50020255 1-[2-(4-Benzoyl-piperazin-1-yl)-ethyl]-imidazolidin-2-one::CHEMBL307465 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208334 103931169 CHEMBL307465 ZINC26378120 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750849 CN1CCN(CCN2CCN(CC2)[C@H]2C[C@@H](c3ccc(F)cc23)c2ccc(F)cc2)C1=O InChI=1S/C25H30F2N4O/c1-28-8-12-31(25(28)32)15-11-29-9-13-30(14-10-29)24-17-22(18-2-4-19(26)5-3-18)21-7-6-20(27)16-23(21)24/h2-7,16,22,24H,8-15,17H2,1H3/t22-,24+/m1/s1 OJVLTRBLPKFAOC-VWNXMTODSA-N 50020226 1-(2-{4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-3-methyl-imidazolidin-2-one::CHEMBL308076 D(2) dopamine receptor Rattus norvegicus 8500 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020226&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18609310 103931140 CHEMBL308076 ZINC26296475 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750850 O=C1NCCN1CCN1CCN(CC1)C1CC(c2ccccc12)c1ccccc1 InChI=1S/C24H30N4O/c29-24-25-10-11-28(24)17-14-26-12-15-27(16-13-26)23-18-22(19-6-2-1-3-7-19)20-8-4-5-9-21(20)23/h1-9,22-23H,10-18H2,(H,25,29) VYMYVEYPDIKLSJ-UHFFFAOYSA-N 50367669 CHEMBL1237335 D(2) dopamine receptor Rattus norvegicus 1900 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208344 160846771 CHEMBL1237335 ZINC26378845 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750856 Fc1ccc(cc1)[C@H]1C[C@H](N2CCNCC2)c2ccccc12 InChI=1S/C19H21FN2/c20-15-7-5-14(6-8-15)18-13-19(22-11-9-21-10-12-22)17-4-2-1-3-16(17)18/h1-8,18-19,21H,9-13H2/t18-,19+/m1/s1 IEXNAGAJXPUXLE-MOPGFXCFSA-N 50367654 CHEMBL1237336 D(2) dopamine receptor Rattus norvegicus 8500 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367654&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312373 160846756 CHEMBL1237336 ZINC26378365 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750857 Fc1ccc(cc1)[C@@H]1C[C@@H](N2CCNCC2)c2ccccc12 InChI=1S/C19H21FN2/c20-15-7-5-14(6-8-15)18-13-19(22-11-9-21-10-12-22)17-4-2-1-3-16(17)18/h1-8,18-19,21H,9-13H2/t18-,19+/m0/s1 IEXNAGAJXPUXLE-RBUKOAKNSA-N 50367667 CHEMBL1237326 D(2) dopamine receptor Rattus norvegicus 580 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367667&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208320 160846769 CHEMBL1237326 ZINC26377350 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750858 Fc1ccc(cc1)[C@H]1C[C@H](N2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H29FN4O/c25-19-7-5-18(6-8-19)22-17-23(21-4-2-1-3-20(21)22)28-14-11-27(12-15-28)13-16-29-10-9-26-24(29)30/h1-8,22-23H,9-17H2,(H,26,30)/t22-,23+/m1/s1 GHAMYXPEZSUOCU-PKTZIBPZSA-N 50367649 CHEMBL1237344 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208321 160846751 CHEMBL1237344 ZINC19359343 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750864 O=C1NCCN1CCN1CCN(CC1)C1CCc2ccccc12 InChI=1S/C18H26N4O/c23-18-19-7-8-22(18)14-11-20-9-12-21(13-10-20)17-6-5-15-3-1-2-4-16(15)17/h1-4,17H,5-14H2,(H,19,23) MUJFYISTRHTMPO-UHFFFAOYSA-N 50020258 1-[2-(4-Indan-1-yl-piperazin-1-yl)-ethyl]-imidazolidin-2-one::CHEMBL312285 D(2) dopamine receptor Rattus norvegicus 62000 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020258&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208336 103931172 CHEMBL312285 ZINC26383342 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750868 O=C1NCCN1CCN1CCN(Cc2ccccc2)CC1 InChI=1S/C16H24N4O/c21-16-17-6-7-20(16)13-12-18-8-10-19(11-9-18)14-15-4-2-1-3-5-15/h1-5H,6-14H2,(H,17,21) UDITWTWTSUFHQU-UHFFFAOYSA-N 50020244 1-[2-(4-Benzyl-piperazin-1-yl)-ethyl]-imidazolidin-2-one::CHEMBL74759 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020244&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208332 103931158 CHEMBL74759 ZINC26383522 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750869 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=S)CC2)c2cc(F)ccc12 InChI=1S/C25H30F2N4S/c26-19-4-2-18(3-5-19)22-17-24(23-16-20(27)6-7-21(22)23)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) ORMXDSNFIZOXNW-UHFFFAOYSA-N 50367672 CHEMBL1237332 D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208369 160846774 CHEMBL1237332 ZINC26379140 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750871 Clc1ccc(cc1)C1CC(N2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H29ClN4O/c25-19-7-5-18(6-8-19)22-17-23(21-4-2-1-3-20(21)22)28-14-11-27(12-15-28)13-16-29-10-9-26-24(29)30/h1-8,22-23H,9-17H2,(H,26,30) FBEYCJGEXYBVOE-UHFFFAOYSA-N 50367665 CHEMBL1237341 D(2) dopamine receptor Rattus norvegicus 800 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367665&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208346 160846767 CHEMBL1237341 ZINC26382320 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750875 CN1CCN(CC1)[C@H]1C[C@@H](c2ccc(F)cc12)c1ccc(F)cc1 InChI=1S/C20H22F2N2/c1-23-8-10-24(11-9-23)20-13-18(14-2-4-15(21)5-3-14)17-7-6-16(22)12-19(17)20/h2-7,12,18,20H,8-11,13H2,1H3/t18-,20+/m1/s1 BOFPIRRSGDHUCZ-QUCCMNQESA-N 50020241 1-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-4-methyl-piperazine::CHEMBL305905 D(2) dopamine receptor Rattus norvegicus 410 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22826279 103931155 CHEMBL305905 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750876 Fc1ccc(cc1)C(=O)N1CCN(CCN2CCNC2=O)CC1 InChI=1S/C16H21FN4O2/c17-14-3-1-13(2-4-14)15(22)20-10-7-19(8-11-20)9-12-21-6-5-18-16(21)23/h1-4H,5-12H2,(H,18,23) ZDCOOXILRWCBLU-UHFFFAOYSA-N 50004321 1-{2-[4-(4-Fluoro-benzoyl)-piperazin-1-yl]-ethyl}-imidazolidin-2-one::CHEMBL72644 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208335 103918004 CHEMBL72644 ZINC26376152 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750880 CN1CCN(CCN2CCN(CC2)[C@@H]2C[C@H](c3ccc(F)cc23)c2ccc(F)cc2)C1=O InChI=1S/C25H30F2N4O/c1-28-8-12-31(25(28)32)15-11-29-9-13-30(14-10-29)24-17-22(18-2-4-19(26)5-3-18)21-7-6-20(27)16-23(21)24/h2-7,16,22,24H,8-15,17H2,1H3/t22-,24+/m0/s1 OJVLTRBLPKFAOC-LADGPHEKSA-N 50020247 1-(2-{4-[6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-3-methyl-imidazolidin-2-one::CHEMBL306960 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208352 103931161 CHEMBL306960 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750883 Oc1ccc(cc1)C1CC(N2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H30N4O2/c29-19-7-5-18(6-8-19)22-17-23(21-4-2-1-3-20(21)22)27-14-11-26(12-15-27)13-16-28-10-9-25-24(28)30/h1-8,22-23,29H,9-17H2,(H,25,30) RFFRELQFYPAOJT-UHFFFAOYSA-N 50367653 CHEMBL1237337 D(2) dopamine receptor Rattus norvegicus 4000 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367653&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14208341 160846755 CHEMBL1237337 ZINC26377717 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750896 CC(C)(C)[C@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25+/m1/s1 ZZJYIKPMDIWRSN-RQTOMXEWSA-N 50292410 (-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(butaclamol)::(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol)::3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((-)-butaclamol)::Butaclamol::CHEMBL479587::l-Butaclamol D(2) dopamine receptor Rattus norvegicus 34000 ChEMBL 10.1021/jm00397a006 10.7270/Q29887KQ 2892932 Liljefors, T; Bogeso, KP University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292410&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24847750 104133961 CHEMBL479587 ZINC40933021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750897 CC(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 InChI=1S/C24H29NO/c1-16(2)24(26)12-13-25-15-21-19-8-4-3-6-17(19)10-11-18-7-5-9-20(23(18)21)22(25)14-24/h3-9,16,21-22,26H,10-15H2,1-2H3/t21-,22-,24-/m0/s1 UPMOVJBGNREKJV-FIXSFTCYSA-N 50019964 3-isopropyl-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::CHEMBL104911 D(2) dopamine receptor Rattus norvegicus 6 ChEMBL 10.1021/jm00397a006 10.7270/Q29887KQ 2892932 Liljefors, T; Bogeso, KP University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20055470 103930887 CHEMBL104911 ZINC01481777 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750898 OCCN1CCN(CC1)[C@H]1C[C@@H](c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2/t19-,21+/m1/s1 JSBWGXQXCRYYTG-CTNGQTDRSA-N 50019965 2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL105013 D(2) dopamine receptor Rattus norvegicus 590 ChEMBL 10.1021/jm00397a006 10.7270/Q29887KQ 2892932 Liljefors, T; Bogeso, KP University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019965&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6917689 103930888 CHEMBL105013 ZINC22937858 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750899 CC(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C24H29NO/c1-16(2)24(26)12-13-25-15-21-19-8-4-3-6-17(19)10-11-18-7-5-9-20(23(18)21)22(25)14-24/h3-9,16,21-22,26H,10-15H2,1-2H3/t21-,22-,24-/m1/s1 UPMOVJBGNREKJV-CQOQZXRMSA-N 50019967 3-isopropyl-(3R,4aR,13bR)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol::CHEMBL320656 D(2) dopamine receptor Rattus norvegicus 900 ChEMBL 10.1021/jm00397a006 10.7270/Q29887KQ 2892932 Liljefors, T; Bogeso, KP University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91267 103930890 CHEMBL320656 ZINC04212893 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750900 CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m1/s1 XRYLGRGAWQSVQW-QGZVFWFLSA-N 50007567 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL64875::OCTOCLOTHEPIN-R D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00397a006 10.7270/Q29887KQ 2892932 Liljefors, T; Bogeso, KP University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603950 103920837 CHEMBL64875 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750901 OCCN1CCN(CC1)[C@@H]1C[C@H](c2ccc(cc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)20-13-16(22(24,25)26)3-6-18(19)20/h1-6,13,19,21,29H,7-12,14H2/t19-,21+/m0/s1 JSBWGXQXCRYYTG-PZJWPPBQSA-N 50019966 2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[3-(4-Fluoro-phenyl)-6-trifluoromethyl-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL95636::Tefludazine D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm00397a006 10.7270/Q29887KQ 2892932 Liljefors, T; Bogeso, KP University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71240 103930889 CHEMBL95636 ZINC22463345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750902 CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1 ZZJYIKPMDIWRSN-TZBSWOFLSA-N 50366495 (+)butaclamol::CHEMBL1255588 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00397a006 10.7270/Q29887KQ 2892932 Liljefors, T; Bogeso, KP University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37461 160845597 73298 CHEMBL1255588 ZINC01481744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750903 CN1CCN(CC1)[C@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m0/s1 XRYLGRGAWQSVQW-KRWDZBQOSA-N 50007568 1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL303313::OCTOCLOTHEPIN-S D(2) dopamine receptor Rattus norvegicus 4.5 ChEMBL 10.1021/jm00397a006 10.7270/Q29887KQ 2892932 Liljefors, T; Bogeso, KP University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12765746 103920838 CHEMBL303313 ZINC19368911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747186 O=C1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H28N4O2S2/c27-20-22(9-3-4-10-22)29-21(28)26(20)12-6-5-11-24-13-15-25(16-14-24)19-17-7-1-2-8-18(17)30-23-19/h1-2,7-8H,3-6,9-16H2 HQMYLWJEICVODO-UHFFFAOYSA-N 50367316 CHEMBL1203226 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367316&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13320442 160846418 CHEMBL1203226 ZINC27202868 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747187 CC1CN(CCCCN2C(=O)CC3(CCCC3)CC2=O)CCN1c1nsc2ccccc12 InChI=1S/C25H34N4O2S/c1-19-18-27(14-15-28(19)24-20-8-2-3-9-21(20)32-26-24)12-6-7-13-29-22(30)16-25(17-23(29)31)10-4-5-11-25/h2-3,8-9,19H,4-7,10-18H2,1H3 GSTHIQFQEPJTJH-UHFFFAOYSA-N 50019367 8-[4-(4-Benzo[d]isothiazol-3-yl-3-methyl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL331221 D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019367&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13568466 103930336 CHEMBL331221 ZINC27199898 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747188 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)C1SNc2ccccc12 InChI=1S/C24H34N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)25-31-23/h1-2,7-8,23,25H,3-6,9-18H2 ONENSZCCSWSBCA-UHFFFAOYSA-N 50019365 8-{4-[4-(1,3-Dihydro-benzo[c]isothiazol-3-yl)-piperazin-1-yl]-butyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL124047 D(2) dopamine receptor Rattus norvegicus 870 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019365&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44347696 103930334 CHEMBL124047 ZINC27193545 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747190 O=C1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C22H28N4O3S/c27-20-22(9-3-4-10-22)30-21(28)26(20)12-6-5-11-24-13-15-25(16-14-24)19-17-7-1-2-8-18(17)29-23-19/h1-2,7-8H,3-6,9-16H2 ACFQQGWJDCVCLT-UHFFFAOYSA-N 50019370 3-[4-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-butyl]-1-thia-3-aza-spiro[4.4]nonane-2,4-dione::CHEMBL121065 D(2) dopamine receptor Rattus norvegicus 78 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019370 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019370&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13320444 103930339 CHEMBL121065 ZINC27187149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747193 C1CN(CCN1)c1noc2ccccc12 InChI=1S/C11H13N3O/c1-2-4-10-9(3-1)11(13-15-10)14-7-5-12-6-8-14/h1-4,12H,5-8H2 ZDFQBFVFCPABKQ-UHFFFAOYSA-N 50367317 CHEMBL1203222 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367317&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232475 160846419 CHEMBL1203222 ZINC12359680 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747194 C1CN(CCN1)c1nsc2ccccc12 InChI=1S/C11H13N3S/c1-2-4-10-9(3-1)11(13-15-10)14-7-5-12-6-8-14/h1-4,12H,5-8H2 KRDOFMHJLWKXIU-UHFFFAOYSA-N 50007695 3-Piperazin-1-yl-benzo[d]isothiazole::Benzisothiazole-3-Yl-Piperazine (Bitp)::CHEMBL1154::CHEMBL1204336 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007695&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2772144 103920965 CHEMBL1204336CHEMBL1154 ZINC02568290 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747196 CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)C1 InChI=1S/C22H30N4O2S/c1-22(2)15-19(27)26(20(28)16-22)10-6-5-9-24-11-13-25(14-12-24)21-17-7-3-4-8-18(17)29-23-21/h3-4,7-8H,5-6,9-16H2,1-2H3 NVMPJRLPVHHXRD-UHFFFAOYSA-N 50019368 1-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4,4-dimethyl-piperidine-2,6-dione::CHEMBL332147 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019368&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232493 103930337 CHEMBL332147 ZINC27194699 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747199 CCC1(CC)CC(=O)N(CCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)C1 InChI=1S/C24H34N4O2S/c1-3-24(4-2)17-21(29)28(22(30)18-24)12-8-7-11-26-13-15-27(16-14-26)23-19-9-5-6-10-20(19)31-25-23/h5-6,9-10H,3-4,7-8,11-18H2,1-2H3 WZYPWDYYXNYUJC-UHFFFAOYSA-N 50367319 CHEMBL1203225 D(2) dopamine receptor Rattus norvegicus 49 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232494 160846421 CHEMBL1203225 ZINC27193276 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747201 Clc1ccc2c(noc2c1)N1CCN(CCCCN2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C24H31ClN4O3/c25-18-5-6-19-20(15-18)32-26-23(19)28-13-11-27(12-14-28)9-3-4-10-29-21(30)16-24(17-22(29)31)7-1-2-8-24/h5-6,15H,1-4,7-14,16-17H2 NBNWDTBOFSRTHK-UHFFFAOYSA-N 50019377 8-{4-[4-(6-Chloro-benzo[d]isoxazol-3-yl)-piperazin-1-yl]-butyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL121774 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232496 103930346 CHEMBL121774 ZINC27199911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747203 Clc1ccc2onc(N3CCN(CCCCN4C(=O)CC5(CCCC5)CC4=O)CC3)c2c1 InChI=1S/C24H31ClN4O3/c25-18-5-6-20-19(15-18)23(26-32-20)28-13-11-27(12-14-28)9-3-4-10-29-21(30)16-24(17-22(29)31)7-1-2-8-24/h5-6,15H,1-4,7-14,16-17H2 FMNYIECFIPKHKQ-UHFFFAOYSA-N 50019366 8-{4-[4-(5-Chloro-benzo[d]isoxazol-3-yl)-piperazin-1-yl]-butyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL333257 D(2) dopamine receptor Rattus norvegicus 360 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019366&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13568460 103930335 CHEMBL333257 ZINC27192135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747204 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCCN(CC1)c1nsc2ccccc12 InChI=1S/C25H34N4O2S/c30-22-18-25(10-3-4-11-25)19-23(31)29(22)15-6-5-12-27-13-7-14-28(17-16-27)24-20-8-1-2-9-21(20)32-26-24/h1-2,8-9H,3-7,10-19H2 AEOVKEFMKKZVSG-UHFFFAOYSA-N 50019374 8-[4-(4-Benzo[d]isothiazol-3-yl-[1,4]diazepan-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL123048 D(2) dopamine receptor Rattus norvegicus 235 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019374&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13568463 103930343 CHEMBL123048 ZINC27194607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747206 OC(CCCN1CCN(CC1)c1noc2ccccc12)c1ccc(F)cc1 InChI=1S/C21H24FN3O2/c22-17-9-7-16(8-10-17)19(26)5-3-11-24-12-14-25(15-13-24)21-18-4-1-2-6-20(18)27-23-21/h1-2,4,6-10,19,26H,3,5,11-15H2 BBNORVNMDRYYOB-UHFFFAOYSA-N 50019376 4-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(4-fluoro-phenyl)-butan-1-ol::CHEMBL331227 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019376&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232490 103930345 CHEMBL331227 ZINC27187142 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747207 Oc1csc(=O)n1CCCCN1CCN(CC1)c1noc2ccc(Cl)cc12 InChI=1S/C18H21ClN4O3S/c19-13-3-4-15-14(11-13)17(20-26-15)22-9-7-21(8-10-22)5-1-2-6-23-16(24)12-27-18(23)25/h3-4,11-12,24H,1-2,5-10H2 NLMIMZQTKYXWIN-UHFFFAOYSA-N 50019362 3-{4-[4-(5-Chloro-benzo[d]isoxazol-3-yl)-piperazin-1-yl]-butyl}-thiazolidine-2,4-dione::CHEMBL124119 D(2) dopamine receptor Rattus norvegicus 440 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019362&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91928948 103930331 CHEMBL124119 ZINC27194402 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747208 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nc2ccccc2s1 InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-25-19-7-1-2-8-20(19)31-23/h1-2,7-8H,3-6,9-18H2 LIMSWAKIMHSXNK-UHFFFAOYSA-N 50019369 8-[4-(4-Benzothiazol-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL122100 D(2) dopamine receptor Rattus norvegicus 145 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019369&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13568465 103930338 CHEMBL122100 ZINC27199015 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747210 Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C21H22FN3O2/c22-17-9-7-16(8-10-17)19(26)5-3-11-24-12-14-25(15-13-24)21-18-4-1-2-6-20(18)27-23-21/h1-2,4,6-10H,3,5,11-15H2 DRWPDXAVBOPONN-UHFFFAOYSA-N 50019375 4-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(4-fluoro-phenyl)-butan-1-one::CHEMBL420164 D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019375&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232488 103930344 CHEMBL420164 ZINC27196519 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747211 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C24H32N4O3/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2 GTBBDTAARHMEGQ-UHFFFAOYSA-N 50019358 8-[4-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL123653 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019358&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232478 103930327 CHEMBL123653 ZINC27197650 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747212 CC1CN(CCN1CCCCN1C(=O)CC2(CCCC2)CC1=O)c1nsc2ccccc12 InChI=1S/C25H34N4O2S/c1-19-18-28(24-20-8-2-3-9-21(20)32-26-24)15-14-27(19)12-6-7-13-29-22(30)16-25(17-23(29)31)10-4-5-11-25/h2-3,8-9,19H,4-7,10-18H2,1H3 CHQUPBFWSFLZTG-UHFFFAOYSA-N 50019380 8-[4-(4-Benzo[d]isothiazol-3-yl-2-methyl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL123121 D(2) dopamine receptor Rattus norvegicus 203 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13568467 103930349 CHEMBL123121 ZINC27194592 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747214 O=C1CC2(CCCC2)CC(=O)N1CCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H30N4O2S/c28-20-16-23(8-3-4-9-23)17-21(29)27(20)11-5-10-25-12-14-26(15-13-25)22-18-6-1-2-7-19(18)30-24-22/h1-2,6-7H,3-5,8-17H2 PYMSCFFQHVXABZ-UHFFFAOYSA-N 50019372 8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-propyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL123133 D(2) dopamine receptor Rattus norvegicus 145 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019372&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13568459 103930341 CHEMBL123133 ZINC27197984 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747215 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747219 Fc1ccc(cc1)C(=O)CCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C21H22FN3OS/c22-17-9-7-16(8-10-17)19(26)5-3-11-24-12-14-25(15-13-24)21-18-4-1-2-6-20(18)27-23-21/h1-2,4,6-10H,3,5,11-15H2 ZTJFXMFDIVEETC-UHFFFAOYSA-N 50019379 4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-1-(4-fluoro-phenyl)-butan-1-one::CHEMBL124291 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019379&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13232484 103930348 CHEMBL124291 ZINC27194185 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747220 Oc1csc(=O)n1CCCCN1CCN(CC1)c1noc2ccccc12 InChI=1S/C18H22N4O3S/c23-16-13-26-18(24)22(16)8-4-3-7-20-9-11-21(12-10-20)17-14-5-1-2-6-15(14)25-19-17/h1-2,5-6,13,23H,3-4,7-12H2 FOKHXYSYKGPXLT-UHFFFAOYSA-N 50019378 3-[4-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-butyl]-thiazolidine-2,4-dione::CHEMBL332241 D(2) dopamine receptor Rattus norvegicus 240 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53810015 103930347 CHEMBL332241 ZINC27194942 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747221 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2 ZFZPJDFBJFHYIV-UHFFFAOYSA-N 50007692 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL1204189::CHEMBL35057::TIOSPERONE D(2) dopamine receptor Rattus norvegicus 8 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55752 103920962 CHEMBL1204189CHEMBL35057 101 ZINC01915508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752675 Cl.Cl.O=C1C2C(C3C=CC2C2C=CC32)S(=O)(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C23H29N5O3S/c29-22-20-18-6-7-19(17-5-4-16(17)18)21(20)32(30,31)28(22)11-2-1-10-26-12-14-27(15-13-26)23-24-8-3-9-25-23/h3-9,16-21H,1-2,10-15H2 YPPGECIVBJQAPM-UHFFFAOYSA-N 50017432 4-{4-[4-(2-pyrimidinyl)hexahydro-1-pyrazinyl]butyl}-5-sulfo-4-azatetracyclo[5.4.2.02,6.08,11]trideca-9,12-dien-3-one; diHydrochloride::CHEMBL3216636 D(2) dopamine receptor Rattus norvegicus 136 ChEMBL 10.1021/jm00125a016 10.7270/Q21G0MVD 2565399 Abou-Gharbia, M; Moyer, JA; Patel, U; Webb, M; Schiehser, G; Andree, T; Haskins, JT Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017432&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90664897 103928700 CHEMBL3216636CHEMBL552663 ZINC34225784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752677 Cl.Cl.O=C1C2C3CC(C=C3)C2S(=O)(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C20H27N5O3S/c26-19-17-15-4-5-16(14-15)18(17)29(27,28)25(19)9-2-1-8-23-10-12-24(13-11-23)20-21-6-3-7-22-20/h3-7,15-18H,1-2,8-14H2 OVMZVMWUKYJJBZ-UHFFFAOYSA-N 50017436 3,3-Dioxo-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-3lambda*6*-thia-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-en-5-one; dihydrochloride::CHEMBL3216189 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm00125a016 10.7270/Q21G0MVD 2565399 Abou-Gharbia, M; Moyer, JA; Patel, U; Webb, M; Schiehser, G; Andree, T; Haskins, JT Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90664647 103928704 CHEMBL3216189CHEMBL542539 ZINC34225769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752680 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 119 ChEMBL 10.1021/jm00125a016 10.7270/Q21G0MVD 2565399 Abou-Gharbia, M; Moyer, JA; Patel, U; Webb, M; Schiehser, G; Andree, T; Haskins, JT Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752682 Cl.Cl.O=C1C2C(C3C=CC2C2CC32)S(=O)(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C22H29N5O3S/c28-21-19-15-4-5-16(18-14-17(15)18)20(19)31(29,30)27(21)9-2-1-8-25-10-12-26(13-11-25)22-23-6-3-7-24-22/h3-7,15-20H,1-2,8-14H2 ZWOLULVBRWRIAN-UHFFFAOYSA-N 50017438 4-{4-[4-(2-pyrimidinyl)hexahydro-1-pyrazinyl]butyl}-5-sulfo-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-en-3-one; diHydrochloride::CHEMBL3216644 D(2) dopamine receptor Rattus norvegicus 1407 ChEMBL 10.1021/jm00125a016 10.7270/Q21G0MVD 2565399 Abou-Gharbia, M; Moyer, JA; Patel, U; Webb, M; Schiehser, G; Andree, T; Haskins, JT Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 20147672 103928706 CHEMBL3216644CHEMBL543246 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752683 Clc1cncc(n1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CC43)S2(=O)=O)CC1 InChI=1S/C22H28ClN5O3S/c23-18-12-24-13-19(25-18)27-9-7-26(8-10-27)5-1-2-6-28-22(29)20-14-3-4-15(17-11-16(14)17)21(20)32(28,30)31/h3-4,12-17,20-21H,1-2,5-11H2 JNAQYZUMZHXNRY-UHFFFAOYSA-N 50017431 4-{4-[4-(6-chloro-2-pyrazinyl)hexahydro-1-pyrazinyl]butyl}-5-sulfo-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-en-3-one; Hydrochloride::CHEMBL552874 D(2) dopamine receptor Rattus norvegicus 1031 ChEMBL 10.1021/jm00125a016 10.7270/Q21G0MVD 2565399 Abou-Gharbia, M; Moyer, JA; Patel, U; Webb, M; Schiehser, G; Andree, T; Haskins, JT Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14099269 103928699 CHEMBL552874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752684 Cl.Cl.O=C1C2C(C3CCC2C=C3)S(=O)(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H29N5O3S/c27-20-18-16-4-6-17(7-5-16)19(18)30(28,29)26(20)11-2-1-10-24-12-14-25(15-13-24)21-22-8-3-9-23-21/h3-4,6,8-9,16-19H,1-2,5,7,10-15H2 COQWDTHYTCXEBF-UHFFFAOYSA-N 50017439 3,3-Dioxo-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-3lambda*6*-thia-4-aza-tricyclo[5.2.2.0*2,6*]undec-8-en-5-one; dihydrochloride::CHEMBL3215739 D(2) dopamine receptor Rattus norvegicus 2000 ChEMBL 10.1021/jm00125a016 10.7270/Q21G0MVD 2565399 Abou-Gharbia, M; Moyer, JA; Patel, U; Webb, M; Schiehser, G; Andree, T; Haskins, JT Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90664384 103928707 CHEMBL3215739CHEMBL537244 ZINC34225773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752688 Clc1nccnc1N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 InChI=1S/C19H22ClN5O3S/c20-17-18(22-8-7-21-17)24-13-11-23(12-14-24)9-3-4-10-25-19(26)15-5-1-2-6-16(15)29(25,27)28/h1-2,5-8H,3-4,9-14H2 LDSKIEVSPOEGTE-UHFFFAOYSA-N 50017441 2-[4-(3'-Chloro-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-butyl]-1,1-dioxo-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one; hydrochloride::CHEMBL543959 D(2) dopamine receptor Rattus norvegicus 493 ChEMBL 10.1021/jm00125a016 10.7270/Q21G0MVD 2565399 Abou-Gharbia, M; Moyer, JA; Patel, U; Webb, M; Schiehser, G; Andree, T; Haskins, JT Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017441&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14099275 103928709 CHEMBL543959 ZINC25982206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752692 Cl.Cl.FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)C3C4CC(C=C4)C3S2(=O)=O)CC1 InChI=1S/C23H28F3N3O3S/c24-23(25,26)18-4-3-5-19(15-18)28-12-10-27(11-13-28)8-1-2-9-29-22(30)20-16-6-7-17(14-16)21(20)33(29,31)32/h3-7,15-17,20-21H,1-2,8-14H2 FFDLQGOMELVLNH-UHFFFAOYSA-N 50017443 3,3-Dioxo-4-{4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-3lambda*6*-thia-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-en-5-one; dihydrochloride::CHEMBL3215971 D(2) dopamine receptor Rattus norvegicus 85 ChEMBL 10.1021/jm00125a016 10.7270/Q21G0MVD 2565399 Abou-Gharbia, M; Moyer, JA; Patel, U; Webb, M; Schiehser, G; Andree, T; Haskins, JT Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90664523 103928711 CHEMBL3215971CHEMBL553756 ZINC36187730 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752696 Clc1nccnc1N1CCN(CCCCN2C(=O)C3C4CCC(O4)C3S2(=O)=O)CC1 InChI=1S/C19H26ClN5O4S/c20-17-18(22-6-5-21-17)24-11-9-23(10-12-24)7-1-2-8-25-19(26)15-13-3-4-14(29-13)16(15)30(25,27)28/h5-6,13-16H,1-4,7-12H2 CEOYGDRLGSXQJK-UHFFFAOYSA-N 50017446 4-[4-(3'-Chloro-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-butyl]-3,3-dioxo-10-oxa-3lambda*6*-thia-4-aza-tricyclo[5.2.1.0*2,6*]decan-5-one; hydrochloride::CHEMBL545359 D(2) dopamine receptor Rattus norvegicus 3300 ChEMBL 10.1021/jm00125a016 10.7270/Q21G0MVD 2565399 Abou-Gharbia, M; Moyer, JA; Patel, U; Webb, M; Schiehser, G; Andree, T; Haskins, JT Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44265054 103928714 CHEMBL545359 ZINC36093019 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50754468 CN(C1CCCC[C@@H]1N1CCCC1)C(=O)Cc1ccc2ccccc2c1 InChI=1S/C23H30N2O/c1-24(21-10-4-5-11-22(21)25-14-6-7-15-25)23(26)17-18-12-13-19-8-2-3-9-20(19)16-18/h2-3,8-9,12-13,16,21-22H,4-7,10-11,14-15,17H2,1H3/t21?,22-/m0/s1 KILKAFDVKRZHIX-KEKNWZKVSA-N 50013955 N-Methyl-2-naphthalen-2-yl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide::N-methyl-2-(naphthalen-2-yl)-N-[(2S)-2-(pyrrolidin-1-yl)cyclohexyl]acetamide D(2) dopamine receptor Rattus norvegicus 7352 ChEMBL 10.1021/jm00173a030 10.7270/Q2348KZJ 2172538 de Costa, BR; Rice, KC; Bowen, WD; Thurkauf, A; Rothman, RB; Band, L; Jacobson, AE; Radesca, L; Contreras, PC; Gray, NM National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44335933 103925989 ZINC26835898 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50754499 CN(C1CCCC[C@@H]1N1CCCC1)C(=O)Cc1cc(Cl)c(Cl)cc1N InChI=1S/C19H27Cl2N3O/c1-23(17-6-2-3-7-18(17)24-8-4-5-9-24)19(25)11-13-10-14(20)15(21)12-16(13)22/h10,12,17-18H,2-9,11,22H2,1H3/t17?,18-/m0/s1 WRHAGKLNUCUJGJ-ZVAWYAOSSA-N 50013968 2-(2-Amino-4,5-dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide D(2) dopamine receptor Rattus norvegicus 1539 ChEMBL 10.1021/jm00173a030 10.7270/Q2348KZJ 2172538 de Costa, BR; Rice, KC; Bowen, WD; Thurkauf, A; Rothman, RB; Band, L; Jacobson, AE; Radesca, L; Contreras, PC; Gray, NM National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013968&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6712736 103926002 ZINC06010249 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758720 CCCN1CCC2=C(C1)c1nc(N)sc1CC2 InChI=1S/C13H19N3S/c1-2-6-16-7-5-9-3-4-11-12(10(9)8-16)15-13(14)17-11/h2-8H2,1H3,(H2,14,15) MMQVSXNDUIHJLN-UHFFFAOYSA-N 50007569 8-Propyl-4,5,6,7,8,9-hexahydro-thiazolo[5,4-h]isoquinolin-2-ylamine::CHEMBL92784 D(2) dopamine receptor Rattus norvegicus 15550 ChEMBL 10.1021/jm00113a010 10.7270/Q2V125FC 1680195 Caprathe, BW; Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT; Parvez, M Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15065264 103920839 CHEMBL92784 ZINC13824114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758725 CCCN1CC=C2C(CCc3sc(N)nc23)C1 InChI=1S/C13H19N3S/c1-2-6-16-7-5-10-9(8-16)3-4-11-12(10)15-13(14)17-11/h5,9H,2-4,6-8H2,1H3,(H2,14,15) HORLZSNHMKBMKI-UHFFFAOYSA-N 50007570 7-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]isoquinolin-2-ylamine::CHEMBL93972 D(2) dopamine receptor Rattus norvegicus 1129 ChEMBL 10.1021/jm00113a010 10.7270/Q2V125FC 1680195 Caprathe, BW; Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT; Parvez, M Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15065269 103920840 CHEMBL93972 ZINC13824118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758726 CCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C11H17N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h4,8H,2-3,5-7H2,1H3,(H2,12,13) VJPANQWIZQHGMJ-UHFFFAOYSA-N 50007573 4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazol-2-ylamine::CHEMBL93428 D(2) dopamine receptor Rattus norvegicus 574 ChEMBL 10.1021/jm00113a010 10.7270/Q2V125FC 1680195 Caprathe, BW; Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT; Parvez, M Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 194775 103920843 CHEMBL93428 ZINC13209017 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758728 CCCN1CCC2=C(CCc3sc(N)nc23)C1 InChI=1S/C13H19N3S/c1-2-6-16-7-5-10-9(8-16)3-4-11-12(10)15-13(14)17-11/h2-8H2,1H3,(H2,14,15) IGLLADILKYAPBC-UHFFFAOYSA-N 50007574 7-Propyl-4,5,6,7,8,9-hexahydro-thiazolo[4,5-f]isoquinolin-2-ylamine::CHEMBL329444 D(2) dopamine receptor Rattus norvegicus 3428 ChEMBL 10.1021/jm00113a010 10.7270/Q2V125FC 1680195 Caprathe, BW; Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT; Parvez, M Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15065270 103920844 CHEMBL329444 ZINC13824120 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758730 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm00113a010 10.7270/Q2V125FC 1680195 Caprathe, BW; Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT; Parvez, M Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758737 CCCN1CCCC2C1CCc1sc(N)nc21 InChI=1S/C13H21N3S/c1-2-7-16-8-3-4-9-10(16)5-6-11-12(9)15-13(14)17-11/h9-10H,2-8H2,1H3,(H2,14,15) YZXHGMLAVBMVDU-UHFFFAOYSA-N 50007575 6-Propyl-4,5,5a,6,7,8,9,9a-octahydro-thiazolo[4,5-f]quinolin-2-ylamine::CHEMBL328548 D(2) dopamine receptor Rattus norvegicus 1235 ChEMBL 10.1021/jm00113a010 10.7270/Q2V125FC 1680195 Caprathe, BW; Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT; Parvez, M Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21298213 103920845 CHEMBL328548 ZINC13824128 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50758740 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Rattus norvegicus 2280 ChEMBL 10.1021/jm00113a010 10.7270/Q2V125FC 1680195 Caprathe, BW; Jaen, JC; Wise, LD; Heffner, TG; Pugsley, TA; Meltzer, LT; Parvez, M Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763228 CCCCN(CCCC)C1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C18H27N3O/c1-3-5-10-20(11-6-4-2)15-12-14-8-7-9-16-17(14)21(13-15)18(22)19-16/h7-9,15H,3-6,10-13H2,1-2H3,(H,19,22) DUYZNNNRBLEHMB-UHFFFAOYSA-N 50001956 5-Dibutylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL12099 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15745010 103916309 CHEMBL12099 ZINC13452391 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763229 CCCN(CCC)C1Cc2cccc3oc(=O)n(C1)c23 InChI=1S/C16H22N2O2/c1-3-8-17(9-4-2)13-10-12-6-5-7-14-15(12)18(11-13)16(19)20-14/h5-7,13H,3-4,8-11H2,1-2H3 HOEALUALDFMXND-UHFFFAOYSA-N 50001957 5-Dipropylamino-5,6-dihydro-4H-oxazolo[5,4,3-ij]quinolin-2-one: p-toluenesulfonate::CHEMBL11729 D(2) dopamine receptor Rattus norvegicus 899 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11250167 103916310 CHEMBL11729 ZINC13452238 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763230 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763231 CCCN(CCC)C1CN2CCc3cccc(C1)c23 InChI=1S/C17H26N2/c1-3-9-18(10-4-2)16-12-15-7-5-6-14-8-11-19(13-16)17(14)15/h5-7,16H,3-4,8-13H2,1-2H3 OYKUWKSHMUIVMA-UHFFFAOYSA-N 50368582 CHEMBL1794997 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368582&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11149594 160847684 CHEMBL1794997 ZINC13452259 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763232 CCCN(Cc1ccccc1)C1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C20H23N3O/c1-2-11-22(13-15-7-4-3-5-8-15)17-12-16-9-6-10-18-19(16)23(14-17)20(24)21-18/h3-10,17H,2,11-14H2,1H3,(H,21,24) OOCMBXNFNITKHR-UHFFFAOYSA-N 50001960 5-(Benzyl-propyl-amino)-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL12285 D(2) dopamine receptor Rattus norvegicus 1914 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15745012 103916313 CHEMBL12285 ZINC13452383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763233 CCCN(CCC)C1Cc2cccc3nc(SC)n(C1)c23 InChI=1S/C17H25N3S/c1-4-9-19(10-5-2)14-11-13-7-6-8-15-16(13)20(12-14)17(18-15)21-3/h6-8,14H,4-5,9-12H2,1-3H3 OJLGWUQOYWYYSO-UHFFFAOYSA-N 50001958 (2-Methylsulfanyl-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-5-yl)-dipropyl-amine::CHEMBL267107 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744957 103916311 CHEMBL267107 ZINC13452217 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763234 CCCN(CCC)C1Cc2cccc3ccn(C1)c23 InChI=1S/C17H24N2/c1-3-9-18(10-4-2)16-12-15-7-5-6-14-8-11-19(13-16)17(14)15/h5-8,11,16H,3-4,9-10,12-13H2,1-2H3 ZKAGDNWCFSWQTI-UHFFFAOYSA-N 50368583 CHEMBL1794999 D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368583&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11311421 160847685 CHEMBL1794999 ZINC13452250 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763236 CCCN(CCC)C1CN2CC(=O)Nc3cccc(C1)c23 InChI=1S/C17H25N3O/c1-3-8-19(9-4-2)14-10-13-6-5-7-15-17(13)20(11-14)12-16(21)18-15/h5-7,14H,3-4,8-12H2,1-2H3,(H,18,21) LFWCFBPVPREGJJ-UHFFFAOYSA-N 50368584 CHEMBL1202415 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368584&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744959 160847686 CHEMBL1202415 ZINC13452275 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763239 CCCN(CCC)C1Cc2cccc3nc(C)n(C1)c23 InChI=1S/C17H25N3/c1-4-9-19(10-5-2)15-11-14-7-6-8-16-17(14)20(12-15)13(3)18-16/h6-8,15H,4-5,9-12H2,1-3H3 LRNPGHLNWKGCPB-UHFFFAOYSA-N 50368585 CHEMBL1202408 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368585 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368585&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15745014 160847687 CHEMBL1202408 ZINC13452234 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763240 CCCN(CCC)C1CN2C(=O)C(=O)c3cccc(C1)c23 InChI=1S/C17H22N2O2/c1-3-8-18(9-4-2)13-10-12-6-5-7-14-15(12)19(11-13)17(21)16(14)20/h5-7,13H,3-4,8-11H2,1-2H3 SWGUTEFASJTIMS-UHFFFAOYSA-N 50001966 5-Dipropylamino-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione::CHEMBL274419 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744985 103916319 CHEMBL274419 ZINC13452267 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763242 C=CCNC1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C13H15N3O/c1-2-6-14-10-7-9-4-3-5-11-12(9)16(8-10)13(17)15-11/h2-5,10,14H,1,6-8H2,(H,15,17) LTMRVOPZSPNZHU-UHFFFAOYSA-N 50368586 CHEMBL1202410 D(2) dopamine receptor Rattus norvegicus 363 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15745005 160847688 CHEMBL1202410 ZINC13452348 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763250 CCCN(CCC)C1CN2C(=O)CNc3cccc(C1)c23 InChI=1S/C17H25N3O/c1-3-8-19(9-4-2)14-10-13-6-5-7-15-17(13)20(12-14)16(21)11-18-15/h5-7,14,18H,3-4,8-12H2,1-2H3 AGDDFINMHZZBNF-UHFFFAOYSA-N 50001971 6-Dipropylamino-1,2,6,7-tetrahydro-5H-pyrido[1,2,3-de]quinoxalin-3-one::CHEMBL268274 D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001971&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744960 103916324 CHEMBL268274 ZINC13452279 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763252 O=c1[nH]c2cccc3CC(Cn1c23)N(CC1CC1)CC1CC1 InChI=1S/C18H23N3O/c22-18-19-16-3-1-2-14-8-15(11-21(18)17(14)16)20(9-12-4-5-12)10-13-6-7-13/h1-3,12-13,15H,4-11H2,(H,19,22) CHKVHTHJMWJGNJ-UHFFFAOYSA-N 50001964 5-(Bis-cyclopropylmethyl-amino)-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL273711 D(2) dopamine receptor Rattus norvegicus 7730 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15745008 103916317 CHEMBL273711 ZINC12356043 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763254 CCCN(CCC)C1Cc2cccc3n(C)c(=O)n(C1)c23 InChI=1S/C17H25N3O/c1-4-9-19(10-5-2)14-11-13-7-6-8-15-16(13)20(12-14)17(21)18(15)3/h6-8,14H,4-5,9-12H2,1-3H3 VKYJURCBISNWGU-UHFFFAOYSA-N 50001972 5-Dipropylamino-1-methyl-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL12515 D(2) dopamine receptor Rattus norvegicus 924 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001972&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744955 103916325 CHEMBL12515 ZINC13452199 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763257 NC1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C10H11N3O/c11-7-4-6-2-1-3-8-9(6)13(5-7)10(14)12-8/h1-3,7H,4-5,11H2,(H,12,14) WZANXVXLOKIMAM-UHFFFAOYSA-N 50368590 CHEMBL1202409 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368590&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15937766 160847692 CHEMBL1202409 ZINC13452335 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763258 CCCNC1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C13H17N3O/c1-2-6-14-10-7-9-4-3-5-11-12(9)16(8-10)13(17)15-11/h3-5,10,14H,2,6-8H2,1H3,(H,15,17) XTWUNLMHXDDOMD-UHFFFAOYSA-N 50368588 CHEMBL1202413 D(2) dopamine receptor Rattus norvegicus 1037 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368588&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11206997 160847690 CHEMBL1202413 ZINC03785751 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763264 CCCN(CCC)C1CN2C(=O)Cc3cccc(C1)c23 InChI=1S/C17H24N2O/c1-3-8-18(9-4-2)15-10-13-6-5-7-14-11-16(20)19(12-15)17(13)14/h5-7,15H,3-4,8-12H2,1-2H3 BYLFIXSYAHAHIR-UHFFFAOYSA-N 50001976 5-Dipropylamino-5,6-dihydro-1H,4H-pyrrolo[3,2,1-ij]quinolin-2-one::CHEMBL11896 D(2) dopamine receptor Rattus norvegicus 1082 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001976&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11311820 103916329 CHEMBL11896 ZINC13452246 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763266 CCCN(CCC)C1Cc2cccc3[nH]c(=S)n(C1)c23 InChI=1S/C16H23N3S/c1-3-8-18(9-4-2)13-10-12-6-5-7-14-15(12)19(11-13)16(20)17-14/h5-7,13H,3-4,8-11H2,1-2H3,(H,17,20) WEUPAXGYFOUDLZ-UHFFFAOYSA-N 50001979 5-Dipropylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinoline-2-thione::CHEMBL12157 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001979&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744956 103916332 CHEMBL12157 ZINC13452207 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763269 CN(C)C1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C12H15N3O/c1-14(2)9-6-8-4-3-5-10-11(8)15(7-9)12(16)13-10/h3-5,9H,6-7H2,1-2H3,(H,13,16) GYEMKOUGMLMNRE-UHFFFAOYSA-N 50368589 CHEMBL1202411 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368589&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11368804 160847691 CHEMBL1202411 ZINC03788021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763271 O=c1[nH]c2cccc3CC(Cn1c23)NCC1CC1 InChI=1S/C14H17N3O/c18-14-16-12-3-1-2-10-6-11(8-17(14)13(10)12)15-7-9-4-5-9/h1-3,9,11,15H,4-8H2,(H,16,18) BZPXXRXAIGZHIA-UHFFFAOYSA-N 50368592 CHEMBL1202412 D(2) dopamine receptor Rattus norvegicus 3996 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368592&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15745007 160847694 CHEMBL1202412 ZINC12355934 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763272 CCCN(CCC)C1CN2C(=O)OCc3cccc(C1)c23 InChI=1S/C17H24N2O2/c1-3-8-18(9-4-2)15-10-13-6-5-7-14-12-21-17(20)19(11-15)16(13)14/h5-7,15H,3-4,8-12H2,1-2H3 JVXNCHSKAILTQZ-UHFFFAOYSA-N 50368593 CHEMBL1202416 D(2) dopamine receptor Rattus norvegicus 292 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368593&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744995 160847695 CHEMBL1202416 ZINC13452309 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763273 CCCN(CCC)C1CN2C(=O)NCc3cccc(C1)c23 InChI=1S/C17H25N3O/c1-3-8-19(9-4-2)15-10-13-6-5-7-14-11-18-17(21)20(12-15)16(13)14/h5-7,15H,3-4,8-12H2,1-2H3,(H,18,21) GZQMSNKBMQEZJK-UHFFFAOYSA-N 50001969 6-Dipropylamino-1,2,6,7-tetrahydro-5H-pyrido[3,2,1-ij]quinazolin-3-one::CHEMBL273867 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001969&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744998 103916322 CHEMBL273867 ZINC13452320 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50736642 C(c1ccccc1)n1c(nc2ccccc12)N1CCNCC1 InChI=1S/C18H20N4/c1-2-6-15(7-3-1)14-22-17-9-5-4-8-16(17)20-18(22)21-12-10-19-11-13-21/h1-9,19H,10-14H2 PWWDCRQZITYKDV-UHFFFAOYSA-N 50103072 1-Benzyl-2-piperazin-1-yl-1H-benzoimidazole::CHEMBL56900::Lerisetron D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(01)00693-x 10.7270/Q20R9PX0 11755351 Iriepa, I; Villasante, FJ; Galvez, E; Labeaga, L; Innerarity, A; Orjales, A Universidad de Alcal£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103072&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65997 103999419 CHEMBL56900 ZINC00007943 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50736646 COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC1CN2C InChI=1S/C16H22ClN3O2/c1-20-8-9-3-4-10(20)5-14(9)19-16(21)11-6-12(17)13(18)7-15(11)22-2/h6-7,9-10,14H,3-5,8,18H2,1-2H3,(H,19,21) KAVKRBZLNSOOJY-UHFFFAOYSA-N 50108390 4-Amino-5-chloro-2-methoxy-N-(2-methyl-2-aza-bicyclo[2.2.2]oct-5-yl)-benzamide::CHEMBL56994 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1016/s0960-894x(01)00693-x 10.7270/Q20R9PX0 11755351 Iriepa, I; Villasante, FJ; Galvez, E; Labeaga, L; Innerarity, A; Orjales, A Universidad de Alcal£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108390&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300153 104003609 CHEMBL56994 ZINC13586867 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50736658 COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC1N(C)C2 InChI=1S/C16H22ClN3O2/c1-20-8-9-3-4-14(20)13(5-9)19-16(21)10-6-11(17)12(18)7-15(10)22-2/h6-7,9,13-14H,3-5,8,18H2,1-2H3,(H,19,21) RQOGVFZHGMQLBX-UHFFFAOYSA-N 50108389 4-Amino-5-chloro-2-methoxy-N-(2-methyl-2-aza-bicyclo[2.2.2]oct-6-yl)-benzamide::CHEMBL57686 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1016/s0960-894x(01)00693-x 10.7270/Q20R9PX0 11755351 Iriepa, I; Villasante, FJ; Galvez, E; Labeaga, L; Innerarity, A; Orjales, A Universidad de Alcal£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108389&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300154 104003608 CHEMBL57686 ZINC13586865 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751219 CC(C)NCC(O)COc1cccc2ccccc12 InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3 AQHHHDLHHXJYJD-UHFFFAOYSA-N 25761 Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine D(2) dopamine receptor Rattus norvegicus 12902 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SNP 1DY4,6EKZ,6PS5,5FUK 4946 56413049 8499 CHEMBL27 DB00571 564 C07407 ZINC00056556 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751220 CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)ccc1OC InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 CANPFCFJURGKAX-JTQLQIEISA-N 50012961 (-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::CHEMBL267723::N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide (IBZM)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide( (S)-(-)IBZM) D(2) dopamine receptor Rattus norvegicus 0.633000 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 107995 103925209 CHEMBL267723 ZINC03786360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751221 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 1.5 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751222 CCN1CCCC1CNC(=O)c1c(O)c(I)ccc1OC InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20) CANPFCFJURGKAX-UHFFFAOYSA-N 50020704 CHEMBL8475::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.430000 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020704&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5120 103931463 CHEMBL8475 ZINC03786360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751223 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 600 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751224 CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1 ZZJYIKPMDIWRSN-TZBSWOFLSA-N 50366495 (+)butaclamol::CHEMBL1255588 D(2) dopamine receptor Rattus norvegicus 0.851000 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37461 160845597 73298 CHEMBL1255588 ZINC01481744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752781 CC1CC(=O)N(CCCCN2CCN(CC2)c2nccc3sccc23)C(=O)C1 InChI=1S/C21H28N4O2S/c1-16-14-19(26)25(20(27)15-16)8-3-2-7-23-9-11-24(12-10-23)21-17-5-13-28-18(17)4-6-22-21/h4-6,13,16H,2-3,7-12,14-15H2,1H3 LKUJZLFUMLHSCS-UHFFFAOYSA-N 50016959 4-Methyl-1-[4-(4-thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-piperidine-2,6-dione; hydrochloride::CHEMBL537924 D(2) dopamine receptor Rattus norvegicus 663 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914140 103928287 CHEMBL537924 ZINC34186871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752783 O=C1CSCC(=O)N1CCCCN1CCN(CC1)c1nccc2occc12 InChI=1S/C19H24N4O3S/c24-17-13-27-14-18(25)23(17)7-2-1-6-21-8-10-22(11-9-21)19-15-4-12-26-16(15)3-5-20-19/h3-5,12H,1-2,6-11,13-14H2 HJQQXGYJQFKRCR-UHFFFAOYSA-N 50016962 4-[4-(4-Furo[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-thiomorpholine-3,5-dione; hydrochloride::CHEMBL542790 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016962&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914144 103928290 CHEMBL542790 ZINC40503761 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752789 O=C1N(CCCCN2CCN(CC2)c2nccc3sccc23)S(=O)(=O)c2ccccc12 InChI=1S/C22H24N4O3S2/c27-22-18-5-1-2-6-20(18)31(28,29)26(22)11-4-3-10-24-12-14-25(15-13-24)21-17-8-16-30-19(17)7-9-23-21/h1-2,5-9,16H,3-4,10-15H2 LIODOFLHMDNDLV-UHFFFAOYSA-N 50016966 1,1-Dioxo-2-[4-(4-thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-1,2-dihydro-1lambda*6*-benzo[d]isothiazol-3-one; hydrochloride::CHEMBL543967 D(2) dopamine receptor Rattus norvegicus 320 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914149 103928294 CHEMBL543967 ZINC01551141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752792 CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2nccc3sccc23)C(=O)C1 InChI=1S/C22H30N4O2S/c1-22(2)15-19(27)26(20(28)16-22)9-4-3-8-24-10-12-25(13-11-24)21-17-6-14-29-18(17)5-7-23-21/h5-7,14H,3-4,8-13,15-16H2,1-2H3 LLHFTQKVWCXGPI-UHFFFAOYSA-N 50016960 4,4-Dimethyl-1-[4-(4-thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-piperidine-2,6-dione; hydrochloride::CHEMBL537702 D(2) dopamine receptor Rattus norvegicus 115 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10364481 103928288 CHEMBL537702 ZINC01536774 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752793 Cc1cc2c(nccc2s1)N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C23H30N4O2S2/c1-17-16-18-19(30-17)6-9-24-20(18)26-14-12-25(13-15-26)10-4-5-11-27-21(28)23(31-22(27)29)7-2-3-8-23/h6,9,16H,2-5,7-8,10-15H2,1H3 FGRXOPGLGIJRPW-UHFFFAOYSA-N 50016967 3-{4-[4-(2-Methyl-thieno[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione; hydrochloride::CHEMBL544203 D(2) dopamine receptor Rattus norvegicus 279 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914133 103928295 CHEMBL544203 ZINC34186865 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752797 Cc1cc2c(nccc2o1)N1CCN(CCCCN2C(=O)CC(C)(C)CC2=O)CC1 InChI=1S/C23H32N4O3/c1-17-14-18-19(30-17)6-7-24-22(18)26-12-10-25(11-13-26)8-4-5-9-27-20(28)15-23(2,3)16-21(27)29/h6-7,14H,4-5,8-13,15-16H2,1-3H3 RLIZPUXPCGFMOI-UHFFFAOYSA-N 50016965 4,4-Dimethyl-1-{4-[4-(2-methyl-furo[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-piperidine-2,6-dione; hydrochloride::CHEMBL544202 D(2) dopamine receptor Rattus norvegicus 708 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016965&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914139 103928293 CHEMBL544202 ZINC36187745 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752798 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 440 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752804 Brc1cc2c(nccc2s1)N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C22H27BrN4O2S2/c23-18-15-16-17(30-18)5-8-24-19(16)26-13-11-25(12-14-26)9-3-4-10-27-20(28)22(31-21(27)29)6-1-2-7-22/h5,8,15H,1-4,6-7,9-14H2 DRRBJWHZVHKSCN-UHFFFAOYSA-N 50016973 3-{4-[4-(2-Bromo-thieno[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione; hydrochloride::CHEMBL543253 D(2) dopamine receptor Rattus norvegicus 440 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016973&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914132 103928301 CHEMBL543253 ZINC34186864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752810 CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2nccc3occc23)C(=O)C1 InChI=1S/C22H30N4O3/c1-22(2)15-19(27)26(20(28)16-22)9-4-3-8-24-10-12-25(13-11-24)21-17-6-14-29-18(17)5-7-23-21/h5-7,14H,3-4,8-13,15-16H2,1-2H3 JYRILLRJWNGMQR-UHFFFAOYSA-N 50016975 1-[4-(4-Furo[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-4,4-dimethyl-piperidine-2,6-dione; hydrochloride::CHEMBL554419 D(2) dopamine receptor Rattus norvegicus 626 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016975&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914138 103928303 CHEMBL554419 ZINC34186870 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752812 Cn1ccc2c(nccc12)N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C23H31N5O2S/c1-25-13-7-18-19(25)6-10-24-20(18)27-16-14-26(15-17-27)11-4-5-12-28-21(29)23(31-22(28)30)8-2-3-9-23/h6-7,10,13H,2-5,8-9,11-12,14-17H2,1H3 ORDSVYXFMRRIFU-UHFFFAOYSA-N 50016976 3-{4-[4-(1-Methyl-1H-pyrrolo[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione; hydrochloride::CHEMBL543493 D(2) dopamine receptor Rattus norvegicus 517 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016976&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914136 103928304 CHEMBL543493 ZINC34186868 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752815 O=C1CSCC(=O)N1CCCCN1CCN(CC1)c1nccc2sccc12 InChI=1S/C19H24N4O2S2/c24-17-13-26-14-18(25)23(17)7-2-1-6-21-8-10-22(11-9-21)19-15-4-12-27-16(15)3-5-20-19/h3-5,12H,1-2,6-11,13-14H2 XTONORBIIMZXAJ-UHFFFAOYSA-N 50016955 4-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-thiomorpholine-3,5-dione::CHEMBL278876 D(2) dopamine receptor Rattus norvegicus 608 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914143 103928283 CHEMBL278876 ZINC34186874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752816 CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2nccc3sc(Br)cc23)C(=O)C1 InChI=1S/C22H29BrN4O2S/c1-22(2)14-19(28)27(20(29)15-22)8-4-3-7-25-9-11-26(12-10-25)21-16-13-18(23)30-17(16)5-6-24-21/h5-6,13H,3-4,7-12,14-15H2,1-2H3 ZJYWNDXQKAEZJP-UHFFFAOYSA-N 50016956 1-{4-[4-(2-Bromo-thieno[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-4,4-dimethyl-piperidine-2,6-dione; hydrochloride::CHEMBL552616 D(2) dopamine receptor Rattus norvegicus 228 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914137 103928284 CHEMBL552616 ZINC34186869 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752818 O=C1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1nccc2sccc12 InChI=1S/C22H28N4O2S2/c27-20-22(7-1-2-8-22)30-21(28)26(20)11-4-3-10-24-12-14-25(15-13-24)19-17-6-16-29-18(17)5-9-23-19/h5-6,9,16H,1-4,7-8,10-15H2 OCBRWFLMBAUWCG-UHFFFAOYSA-N 50016964 3-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-1-thia-3-aza-spiro[4.4]nonane-2,4-dione; hydrochloride::CHEMBL537707 D(2) dopamine receptor Rattus norvegicus 88 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914131 103928292 CHEMBL537707 ZINC34186863 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752819 O=C1COCC(=O)N1CCCCN1CCN(CC1)c1nccc2occc12 InChI=1S/C19H24N4O4/c24-17-13-26-14-18(25)23(17)7-2-1-6-21-8-10-22(11-9-21)19-15-4-12-27-16(15)3-5-20-19/h3-5,12H,1-2,6-11,13-14H2 QBICJHHCQYFVMI-UHFFFAOYSA-N 50016961 4-[4-(4-Furo[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-morpholine-3,5-dione::CHEMBL16072 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 184633 103928289 CHEMBL16072 ZINC31502170 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763276 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763277 CCCN(CCC)C1Cc2cccc3ncc(=O)n(C1)c23 InChI=1S/C17H23N3O/c1-3-8-19(9-4-2)14-10-13-6-5-7-15-17(13)20(12-14)16(21)11-18-15/h5-7,11,14H,3-4,8-10,12H2,1-2H3 ZUNQTXSGJHYWAG-UHFFFAOYSA-N 50001980 6-Dipropylamino-6,7-dihydro-5H-pyrido[1,2,3-de]quinoxalin-3-one::CHEMBL275572 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001980&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744961 103916333 CHEMBL275572 ZINC13452283 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763278 CCCN(CCC)C1CN2C(=O)COc3cccc(C1)c23 InChI=1S/C17H24N2O2/c1-3-8-18(9-4-2)14-10-13-6-5-7-15-17(13)19(11-14)16(20)12-21-15/h5-7,14H,3-4,8-12H2,1-2H3 HTTOQWRXSYPSPD-UHFFFAOYSA-N 50368591 CHEMBL1794795 D(2) dopamine receptor Rattus norvegicus 1348 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744977 160847693 CHEMBL1794795 ZINC12356015 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763280 CCCN(CCC)C1CN2CCCc3cccc(C1)c23 InChI=1S/C18H28N2/c1-3-10-19(11-4-2)17-13-16-8-5-7-15-9-6-12-20(14-17)18(15)16/h5,7-8,17H,3-4,6,9-14H2,1-2H3 GWMBKHSMFOROGY-UHFFFAOYSA-N 50368594 CHEMBL1794998 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15745003 160847696 CHEMBL1794998 ZINC13452325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763281 CCCN(CCC)C1Cc2cccc3ccc(=O)n(C1)c23 InChI=1S/C18H24N2O/c1-3-10-19(11-4-2)16-12-15-7-5-6-14-8-9-17(21)20(13-16)18(14)15/h5-9,16H,3-4,10-13H2,1-2H3 TZJYXVGLMBIOAB-UHFFFAOYSA-N 50001977 6-Dipropylamino-6,7-dihydro-5H-pyrido[3,2,1-ij]quinolin-3-one::CHEMBL269419 D(2) dopamine receptor Rattus norvegicus 315 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001977&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744989 103916330 CHEMBL269419 ZINC13452291 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763285 CCCN(CCC)C1CN2C(=O)CCc3cccc(C1)c23 InChI=1S/C18H26N2O/c1-3-10-19(11-4-2)16-12-15-7-5-6-14-8-9-17(21)20(13-16)18(14)15/h5-7,16H,3-4,8-13H2,1-2H3 WIUIXLAZQHEPHZ-UHFFFAOYSA-N 50001974 6-Dipropylamino-1,2,6,7-tetrahydro-5H-pyrido[3,2,1-ij]quinolin-3-one::CHEMBL11577 D(2) dopamine receptor Rattus norvegicus 83 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001974&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744991 103916327 CHEMBL11577 ZINC13452300 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763286 CCCN(CCC)[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C16H23N3O/c1-3-8-18(9-4-2)13-10-12-6-5-7-14-15(12)19(11-13)16(20)17-14/h5-7,13H,3-4,8-11H2,1-2H3,(H,17,20)/t13-/m1/s1 UCZYAFAFGFTZEW-CYBMUJFWSA-N 50368595 CHEMBL1744080 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131559 160847697 CHEMBL1744080 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763287 CCCN(CCC)C1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C16H23N3O/c1-3-8-18(9-4-2)13-10-12-6-5-7-14-15(12)19(11-13)16(20)17-14/h5-7,13H,3-4,8-11H2,1-2H3,(H,17,20) UCZYAFAFGFTZEW-UHFFFAOYSA-N 50368587 CHEMBL1202407 D(2) dopamine receptor Rattus norvegicus 207 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11459998 160847689 CHEMBL1202407 ZINC03788022 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763291 C=CCN(CC=C)C1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C16H19N3O/c1-3-8-18(9-4-2)13-10-12-6-5-7-14-15(12)19(11-13)16(20)17-14/h3-7,13H,1-2,8-11H2,(H,17,20) ICPOJMTVQMOION-UHFFFAOYSA-N 50001987 5-Diallylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL441331 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15745006 103916340 CHEMBL441331 ZINC13452366 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763292 CCCCN(CCC)C1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C17H25N3O/c1-3-5-10-19(9-4-2)14-11-13-7-6-8-15-16(13)20(12-14)17(21)18-15/h6-8,14H,3-5,9-12H2,1-2H3,(H,18,21) FTRKOPFMBOWMOY-UHFFFAOYSA-N 50001978 5-(Butyl-propyl-amino)-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL12021 D(2) dopamine receptor Rattus norvegicus 167 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001978&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15745011 103916331 CHEMBL12021 ZINC13452375 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763293 CCCN(CCC)C1Cc2cccc3ncn(C1)c23 InChI=1S/C16H23N3/c1-3-8-18(9-4-2)14-10-13-6-5-7-15-16(13)19(11-14)12-17-15/h5-7,12,14H,3-4,8-11H2,1-2H3 XOWDSADVJRDFTM-UHFFFAOYSA-N 50001962 (5,6-Dihydro-4H-imidazo[4,5,1-ij]quinolin-5-yl)-dipropyl-amine::CHEMBL417612 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001962&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11196186 103916315 CHEMBL417612 ZINC13452224 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763295 CCCN(CCC)C1Cc2cccc3[nH]c(=O)c(=O)n(C1)c23 InChI=1S/C17H23N3O2/c1-3-8-19(9-4-2)13-10-12-6-5-7-14-15(12)20(11-13)17(22)16(21)18-14/h5-7,13H,3-4,8-11H2,1-2H3,(H,18,21) FHPMAVRSFDZOBR-UHFFFAOYSA-N 50368596 CHEMBL1202414 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368596&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15744962 160847698 CHEMBL1202414 ZINC04626911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763297 CCCCNC1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C14H19N3O/c1-2-3-7-15-11-8-10-5-4-6-12-13(10)17(9-11)14(18)16-12/h4-6,11,15H,2-3,7-9H2,1H3,(H,16,18) NRLIHXRPOFGROM-UHFFFAOYSA-N 50001986 5-Butylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL12247 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00084a013 10.7270/Q2DB82GX 1348089 Moon, MW; Morris, JK; Heier, RF; Chidester, CG; Hoffmann, WE; Piercey, MF; Althaus, JS; Von Voigtlander, PF; Evans, DL; Figur, LM Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001986&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15745009 103916339 CHEMBL12247 ZINC13452358 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50749510 CSc1ccc(cc1)[C@@H]1CN2CCC[C@@H]2c2ccccc12 InChI=1S/C19H21NS/c1-21-15-10-8-14(9-11-15)18-13-20-12-4-7-19(20)17-6-3-2-5-16(17)18/h2-3,5-6,8-11,18-19H,4,7,12-13H2,1H3/t18-,19+/m0/s1 YVKDUIAAPBKHMJ-RBUKOAKNSA-N 50021887 6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline::6-(4-Methylsulfanyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline;HClO4::CHEMBL34990 D(2) dopamine receptor Rattus norvegicus 1030 ChEMBL 10.1021/jm00391a028 10.7270/Q2D50NJ3 3039136 Maryanoff, BE; McComsey, DF; Gardocki, JF; Shank, RP; Costanzo, MJ; Nortey, SO; Schneider, CR; Setler, PE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021887&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036461 103932577 CHEMBL34990 ZINC06019879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50749547 FC(F)(F)c1cccc(c1)[C@@H]1CN2CCC[C@@H]2c2ccccc12 InChI=1S/C19H18F3N/c20-19(21,22)14-6-3-5-13(11-14)17-12-23-10-4-9-18(23)16-8-2-1-7-15(16)17/h1-3,5-8,11,17-18H,4,9-10,12H2/t17-,18+/m0/s1 LWXKKDYZAXBAPH-ZWKOTPCHSA-N 50021912 6-(3-Trifluoromethyl-phenyl)-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline;HCl::CHEMBL286849 D(2) dopamine receptor Rattus norvegicus 2220 ChEMBL 10.1021/jm00391a028 10.7270/Q2D50NJ3 3039136 Maryanoff, BE; McComsey, DF; Gardocki, JF; Shank, RP; Costanzo, MJ; Nortey, SO; Schneider, CR; Setler, PE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021912&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13646491 103932602 CHEMBL286849 ZINC29239407 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50749479 COc1cc2[C@@H]3CCCN3C[C@@H](c3ccccc3)c2cc1OC InChI=1S/C20H23NO2/c1-22-19-11-15-16(12-20(19)23-2)18-9-6-10-21(18)13-17(15)14-7-4-3-5-8-14/h3-5,7-8,11-12,17-18H,6,9-10,13H2,1-2H3/t17-,18-/m0/s1 RKFMEOUFVPJFKZ-ROUUACIJSA-N 50367565 CHEMBL1743804 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm00391a028 10.7270/Q2D50NJ3 3039136 Maryanoff, BE; McComsey, DF; Gardocki, JF; Shank, RP; Costanzo, MJ; Nortey, SO; Schneider, CR; Setler, PE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44282127 160846667 CHEMBL1743804 ZINC29231362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751226 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 359 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751228 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.149000 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751229 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.170000 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751231 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 296 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751232 CCN1CCC[C@H]1CNC(=O)c1c(O)cccc1OC InChI=1S/C15H22N2O3/c1-3-17-9-5-6-11(17)10-16-15(19)14-12(18)7-4-8-13(14)20-2/h4,7-8,11,18H,3,5-6,9-10H2,1-2H3,(H,16,19)/t11-/m0/s1 MVWKVVFFVMXULU-NSHDSACASA-N 50012964 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::CHEMBL8945::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (BZM) D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10956830 103925212 CHEMBL8945 ZINC05851787 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751234 CCN1CCC[C@@H]1CNC(=O)c1c(O)c(I)ccc1OC InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m1/s1 CANPFCFJURGKAX-SNVBAGLBSA-N 50020705 CHEMBL8674::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020705&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603877 103931464 CHEMBL8674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752821 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752825 C1CN(CCN1)c1nccc2sccc12 InChI=1S/C11H13N3S/c1-3-13-11(9-2-8-15-10(1)9)14-6-4-12-5-7-14/h1-3,8,12H,4-7H2 RVGRTFBJOXMFAX-UHFFFAOYSA-N 50016970 4-Piperazin-1-yl-thieno[3,2-c]pyridine; hydrochloride::CHEMBL552833::CHEMBL608135 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016970&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10966027 103928298 CHEMBL552833CHEMBL608135 ZINC15443139 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752828 C1CN(CCN1)c1nccc2occc12 InChI=1S/C11H13N3O/c1-3-13-11(9-2-8-15-10(1)9)14-6-4-12-5-7-14/h1-3,8,12H,4-7H2 LUIZVTKJWSGSPA-UHFFFAOYSA-N 50016972 4-Piperazin-1-yl-furo[3,2-c]pyridine; hydrochloride::CHEMBL543969::CHEMBL595555 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016972&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2794808 103928300 CHEMBL543969CHEMBL595555 ZINC20231043 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752830 Cn1ccc2c(nccc12)N1CCN(CCCCN2C(=O)CC(C)(C)CC2=O)CC1 InChI=1S/C23H33N5O2/c1-23(2)16-20(29)28(21(30)17-23)10-5-4-9-26-12-14-27(15-13-26)22-18-7-11-25(3)19(18)6-8-24-22/h6-8,11H,4-5,9-10,12-17H2,1-3H3 GMZNQMSZVPCDLB-UHFFFAOYSA-N 50016978 4,4-Dimethyl-1-{4-[4-(1-methyl-1H-pyrrolo[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-piperidine-2,6-dione; hydrochloride::CHEMBL540253 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016978&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914142 103928306 CHEMBL540253 ZINC34186873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752832 O=C1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1nccc2ccsc12 InChI=1S/C22H28N4O2S2/c27-20-22(7-1-2-8-22)30-21(28)26(20)11-4-3-10-24-12-14-25(15-13-24)19-18-17(5-9-23-19)6-16-29-18/h5-6,9,16H,1-4,7-8,10-15H2 RUENTAABOQZLLF-UHFFFAOYSA-N 50016957 3-[4-(4-Thieno[2,3-c]pyridin-7-yl-piperazin-1-yl)-butyl]-1-thia-3-aza-spiro[4.4]nonane-2,4-dione; hydrochloride::CHEMBL558026 D(2) dopamine receptor Rattus norvegicus 418 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914151 103928285 CHEMBL558026 ZINC34186881 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752833 O=C1N(CCCCN2CCN(CC2)c2nccc3sccc23)C(=O)c2ccccc12 InChI=1S/C23H24N4O2S/c28-22-17-5-1-2-6-18(17)23(29)27(22)11-4-3-10-25-12-14-26(15-13-25)21-19-8-16-30-20(19)7-9-24-21/h1-2,5-9,16H,3-4,10-15H2 GTWNHABCHSGVMM-UHFFFAOYSA-N 50016963 2-[4-(4-Thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-isoindole-1,3-dione; hydrochloride::CHEMBL554473 D(2) dopamine receptor Rattus norvegicus 306 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016963&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914150 103928291 CHEMBL554473 ZINC01551140 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752834 Cc1cc2c(nccc2o1)N1CCN(CCCCN2C(=O)SC3(CCCC3)C2=O)CC1 InChI=1S/C23H30N4O3S/c1-17-16-18-19(30-17)6-9-24-20(18)26-14-12-25(13-15-26)10-4-5-11-27-21(28)23(31-22(27)29)7-2-3-8-23/h6,9,16H,2-5,7-8,10-15H2,1H3 XKTCRHODWQUSIJ-UHFFFAOYSA-N 50016971 3-{4-[4-(2-Methyl-furo[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonane-2,4-dione; hydrochloride::CHEMBL536797 D(2) dopamine receptor Rattus norvegicus 751 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016971&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914135 103928299 CHEMBL536797 ZINC34186867 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752837 OC(CCCN1CCN(CC1)c1nccc2occc12)c1ccc(F)cc1 InChI=1S/C21H24FN3O2/c22-17-5-3-16(4-6-17)19(26)2-1-10-24-11-13-25(14-12-24)21-18-8-15-27-20(18)7-9-23-21/h3-9,15,19,26H,1-2,10-14H2 GMRUSTMCIXDTFD-UHFFFAOYSA-N 50016974 1-(4-Fluoro-phenyl)-4-(4-furo[3,2-c]pyridin-4-yl-piperazin-1-yl)-butan-1-ol; hydrochloride::CHEMBL542789 D(2) dopamine receptor Rattus norvegicus 339 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016974&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914147 103928302 CHEMBL542789 ZINC34186879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752838 O=C1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1nccc2occc12 InChI=1S/C22H28N4O3S/c27-20-22(7-1-2-8-22)30-21(28)26(20)11-4-3-10-24-12-14-25(15-13-24)19-17-6-16-29-18(17)5-9-23-19/h5-6,9,16H,1-4,7-8,10-15H2 OJQUSDGNLXISBU-UHFFFAOYSA-N 50016977 3-[4-(4-Furo[3,2-c]pyridin-4-yl-piperazin-1-yl)-butyl]-1-thia-3-aza-spiro[4.4]nonane-2,4-dione; hydrochloride::CHEMBL553758 D(2) dopamine receptor Rattus norvegicus 331 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016977&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914134 103928305 CHEMBL553758 ZINC34186866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752839 Cn1ccc2c(nccc12)N1CCN(CCCCN2C(=O)COCC2=O)CC1 InChI=1S/C20H27N5O3/c1-22-9-5-16-17(22)4-6-21-20(16)24-12-10-23(11-13-24)7-2-3-8-25-18(26)14-28-15-19(25)27/h4-6,9H,2-3,7-8,10-15H2,1H3 LMCWHRGQHKPHCK-UHFFFAOYSA-N 50016979 4-{4-[4-(1-Methyl-1H-pyrrolo[3,2-c]pyridin-4-yl)-piperazin-1-yl]-butyl}-morpholine-3,5-dione; hydrochloride::CHEMBL553318 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016979&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914145 103928307 CHEMBL553318 ZINC34186875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50752841 OC(CCCN1CCN(CC1)c1nccc2sccc12)c1ccc(F)cc1 InChI=1S/C21H24FN3OS/c22-17-5-3-16(4-6-17)19(26)2-1-10-24-11-13-25(14-12-24)21-18-8-15-27-20(18)7-9-23-21/h3-9,15,19,26H,1-2,10-14H2 YZSXHWKLZRAMBW-UHFFFAOYSA-N 50016958 1-(4-Fluoro-phenyl)-4-(4-thieno[3,2-c]pyridin-4-yl-piperazin-1-yl)-butan-1-ol::CHEMBL15560 D(2) dopamine receptor Rattus norvegicus 72 ChEMBL 10.1021/jm00126a002 10.7270/Q2HD7W8D 2542551 New, JS; Christopher, WL; Yevich, JP; Butler, R; Schlemmer, RF; VanderMaelen, CP; Cipollina, JA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13914146 103928286 CHEMBL15560 ZINC34186877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50749556 Fc1ccc(cc1)[C@@H]1CN2CCC[C@@H]2c2cc(F)ccc12 InChI=1S/C18H17F2N/c19-13-5-3-12(4-6-13)17-11-21-9-1-2-18(21)16-10-14(20)7-8-15(16)17/h3-8,10,17-18H,1-2,9,11H2/t17-,18+/m0/s1 AKWMCQOXGLJZLJ-ZWKOTPCHSA-N 50367559 CHEMBL1743798 D(2) dopamine receptor Rattus norvegicus 241 ChEMBL 10.1021/jm00391a028 10.7270/Q2D50NJ3 3039136 Maryanoff, BE; McComsey, DF; Gardocki, JF; Shank, RP; Costanzo, MJ; Nortey, SO; Schneider, CR; Setler, PE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13903144 160846661 CHEMBL1743798 ZINC29231013 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757260 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 630 ChEMBL 10.1021/jm00106a023 10.7270/Q29887M5 1995885 Kato, S; Morie, T; Kon, T; Yoshida, N; Karasawa, T; Matsumoto, J Dainippon Pharmaceutical Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757265 COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29) DCSUBABJRXZOMT-UHFFFAOYSA-N 50005836 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide::4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::CHEMBL560739::CISAPRIDE::PROPULSID::US10167299, Cisapride::US10800776, Example Cisapride::US9221790, Cisapride::cid_5311047 D(2) dopamine receptor Rattus norvegicus 390 ChEMBL 10.1021/jm00106a023 10.7270/Q29887M5 1995885 Kato, S; Morie, T; Kon, T; Yoshida, N; Karasawa, T; Matsumoto, J Dainippon Pharmaceutical Company, Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005836&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2769 103919261 CHEMBL560739 240 C06910 ZINC03830564 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50735435 COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4ccccc4)c3c2=O)CC1 InChI=1S/C25H26N4O3S/c1-32-21-10-6-5-9-20(21)28-14-11-27(12-15-28)13-16-29-24(30)22-19(18-7-3-2-4-8-18)17-33-23(22)26-25(29)31/h2-10,17H,11-16H2,1H3,(H,26,31) HLVQBOYEHQRWHG-UHFFFAOYSA-N 50099322 3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-5-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione::A-119637::CHEMBL268758 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1016/s0960-894x(01)00159-7 10.7270/Q20V8DBQ 11354357 Carroll, WA; Sippy, KB; Esbenshade, TA; Buckner, SA; Hancock, AA; Meyer, MD Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099322&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9890547 103996238 CHEMBL268758 490 ZINC01487800 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50735444 COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4cccc(C)c4)c3c2=O)CC1 InChI=1S/C26H28N4O3S/c1-18-6-5-7-19(16-18)20-17-34-24-23(20)25(31)30(26(32)27-24)15-12-28-10-13-29(14-11-28)21-8-3-4-9-22(21)33-2/h3-9,16-17H,10-15H2,1-2H3,(H,27,32) PANBMHHKBRMYAL-UHFFFAOYSA-N 50099325 3-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-5-m-tolyl-1H-thieno[2,3-d]pyrimidine-2,4-dione::A-123189::CHEMBL13856 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1016/s0960-894x(01)00159-7 10.7270/Q20V8DBQ 11354357 Carroll, WA; Sippy, KB; Esbenshade, TA; Buckner, SA; Hancock, AA; Meyer, MD Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50099325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50099325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9891167 103996241 CHEMBL13856 491 ZINC34014527 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747700 Clc1c2C(=O)N(CCCCN3CCN(CC3)c3ncccn3)C(=O)c2c(Cl)c(Cl)c1Cl InChI=1S/C20H19Cl4N5O2/c21-14-12-13(15(22)17(24)16(14)23)19(31)29(18(12)30)7-2-1-6-27-8-10-28(11-9-27)20-25-4-3-5-26-20/h3-5H,1-2,6-11H2 GTQXYQJYPGXPCJ-UHFFFAOYSA-N 50019421 4,5,6,7-Tetrachloro-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-isoindole-1,3-dione::CHEMBL34017 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476620 103930376 CHEMBL34017 ZINC29245532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747703 O=C1N(CCCCN2CCN(CC2)c2ncccn2)C(=O)c2ccccc12 InChI=1S/C20H23N5O2/c26-18-16-6-1-2-7-17(16)19(27)25(18)11-4-3-10-23-12-14-24(15-13-23)20-21-8-5-9-22-20/h1-2,5-9H,3-4,10-15H2 QFMFYDYACBTMIQ-UHFFFAOYSA-N 50019422 2-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-isoindole-1,3-dione::CHEMBL281720 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406539 103930377 CHEMBL281720 ZINC28048479 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747704 O=C1CC2(CCCc3ccccc23)C(=O)N1CCCCN1CCN(CC1)N1Cc2ccccc2S1 InChI=1S/C28H34N4O2S/c33-26-20-28(13-7-10-22-8-1-3-11-24(22)28)27(34)31(26)15-6-5-14-29-16-18-30(19-17-29)32-21-23-9-2-4-12-25(23)35-32/h1-4,8-9,11-12H,5-7,10,13-21H2 ULYILJGCAPRQBC-UHFFFAOYSA-N 50367354 CHEMBL1744357 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367354&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283353 160846456 CHEMBL1744357 ZINC29245519 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747705 O=C1C2CC=CCC2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C20H27N5O2/c26-18-16-6-1-2-7-17(16)19(27)25(18)11-4-3-10-23-12-14-24(15-13-23)20-21-8-5-9-22-20/h1-2,5,8-9,16-17H,3-4,6-7,10-15H2 UXRFGKLHVVIEGM-UHFFFAOYSA-N 50367355 CHEMBL1202534 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15592391 160846457 CHEMBL1202534 ZINC29234445 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747706 O=C1CC(C(=O)N1CCCCN1CCN(CC1)c1ncccc1C#N)(c1ccccc1)c1ccccc1 InChI=1S/C30H31N5O2/c31-23-24-10-9-15-32-28(24)34-20-18-33(19-21-34)16-7-8-17-35-27(36)22-30(29(35)37,25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-6,9-15H,7-8,16-22H2 SITHJHTXKROCJG-UHFFFAOYSA-N 50019425 2-{4-[4-(2,5-Dioxo-3,3-diphenyl-pyrrolidin-1-yl)-butyl]-piperazin-1-yl}-nicotinonitrile::CHEMBL288101 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019425&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476605 103930380 CHEMBL288101 ZINC29248427 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747707 O=C1CC2(CCc3ccccc3C2)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C25H31N5O2/c31-22-19-25(9-8-20-6-1-2-7-21(20)18-25)23(32)30(22)13-4-3-12-28-14-16-29(17-15-28)24-26-10-5-11-27-24/h1-2,5-7,10-11H,3-4,8-9,12-19H2 YLIUOKCBMMVWDS-UHFFFAOYSA-N 50367356 CHEMBL1202532 D(2) dopamine receptor Rattus norvegicus 540 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476589 160846458 CHEMBL1202532 ZINC29245378 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747708 CC1(CC(=O)N(CCCN2CCN(CC2)c2ncccn2)C1=O)c1ccc(F)cc1 InChI=1S/C22H26FN5O2/c1-22(17-4-6-18(23)7-5-17)16-19(29)28(20(22)30)11-3-10-26-12-14-27(15-13-26)21-24-8-2-9-25-21/h2,4-9H,3,10-16H2,1H3 MAMCILWMZSICJV-UHFFFAOYSA-N 50019427 3-(4-Fluoro-phenyl)-3-methyl-1-[3-(4-pyrimidin-2-yl-piperazin-1-yl)-propyl]-pyrrolidine-2,5-dione::CHEMBL416408 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476601 103930382 CHEMBL416408 ZINC29242568 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747710 O=C1CC2(CCc3ccccc23)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C24H29N5O2/c30-21-18-24(9-8-19-6-1-2-7-20(19)24)22(31)29(21)13-4-3-12-27-14-16-28(17-15-27)23-25-10-5-11-26-23/h1-2,5-7,10-11H,3-4,8-9,12-18H2 UMSZLPCKNCRNDE-UHFFFAOYSA-N 50367357 CHEMBL1202535 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367357&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13660337 160846459 CHEMBL1202535 ZINC29247192 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747711 CC1(CC(=O)N(CCN2CCN(CC2)c2ncccn2)C1=O)c1ccc(F)cc1 InChI=1S/C21H24FN5O2/c1-21(16-3-5-17(22)6-4-16)15-18(28)27(19(21)29)14-11-25-9-12-26(13-10-25)20-23-7-2-8-24-20/h2-8H,9-15H2,1H3 MYWHNQVWNJFKEM-UHFFFAOYSA-N 50019431 3-(4-Fluoro-phenyl)-3-methyl-1-[2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl]-pyrrolidine-2,5-dione::CHEMBL36175 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476599 103930386 CHEMBL36175 ZINC29241668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747712 CC1(CC(=O)N(CCCCN2CCN(CC2)c2ncccc2C#N)C1=O)c1ccc(F)cc1 InChI=1S/C25H28FN5O2/c1-25(20-6-8-21(26)9-7-20)17-22(32)31(24(25)33)12-3-2-11-29-13-15-30(16-14-29)23-19(18-27)5-4-10-28-23/h4-10H,2-3,11-17H2,1H3 NSYFXMURKJWXBZ-UHFFFAOYSA-N 50019430 2-(4-{4-[3-(4-Fluoro-phenyl)-3-methyl-2,5-dioxo-pyrrolidin-1-yl]-butyl}-piperazin-1-yl)-nicotinonitrile::CHEMBL35538 D(2) dopamine receptor Rattus norvegicus 710 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019430&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476603 103930385 CHEMBL35538 ZINC29249257 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747713 O=C1CC2(CCCc3ccccc23)C(=O)N1CCCCN1CCN(CC1)c1ncccc1C#N InChI=1S/C27H31N5O2/c28-20-22-9-6-12-29-25(22)31-17-15-30(16-18-31)13-3-4-14-32-24(33)19-27(26(32)34)11-5-8-21-7-1-2-10-23(21)27/h1-2,6-7,9-10,12H,3-5,8,11,13-19H2 QZSZGQXOPJEOQG-UHFFFAOYSA-N 50367358 CHEMBL1202536 D(2) dopamine receptor Rattus norvegicus 310 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367358&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476614 160846460 CHEMBL1202536 ZINC29244511 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747715 [O-][N+](=O)c1ccc2C(=O)N(CCCCN3CCN(CC3)c3ncccn3)C(=O)c2c1 InChI=1S/C20H22N6O4/c27-18-16-5-4-15(26(29)30)14-17(16)19(28)25(18)9-2-1-8-23-10-12-24(13-11-23)20-21-6-3-7-22-20/h3-7,14H,1-2,8-13H2 CSTILXPGLBTWAF-UHFFFAOYSA-N 50019433 5-Nitro-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-isoindole-1,3-dione::CHEMBL284602 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476621 103930388 CHEMBL284602 ZINC29252589 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747716 Clc1cc2C(=O)N(CCCCN3CCN(CC3)c3ncccn3)C(=O)c2cc1Cl InChI=1S/C20H21Cl2N5O2/c21-16-12-14-15(13-17(16)22)19(29)27(18(14)28)7-2-1-6-25-8-10-26(11-9-25)20-23-4-3-5-24-20/h3-5,12-13H,1-2,6-11H2 DRCSETNTACRVAJ-UHFFFAOYSA-N 50019435 5,6-Dichloro-2-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-isoindole-1,3-dione::CHEMBL287604 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019435&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476619 103930390 CHEMBL287604 ZINC29306758 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747718 O=C1CC(C(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12)(c1ccccc1)c1ccccc1 InChI=1S/C31H32N4O2S/c36-28-23-31(24-11-3-1-4-12-24,25-13-5-2-6-14-25)30(37)35(28)18-10-9-17-33-19-21-34(22-20-33)29-26-15-7-8-16-27(26)38-32-29/h1-8,11-16H,9-10,17-23H2 MWYWEZQRISXVNW-UHFFFAOYSA-N 50019434 1-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3,3-diphenyl-pyrrolidine-2,5-dione::CHEMBL34146 D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476608 103930389 CHEMBL34146 ZINC29248518 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747720 O=C1CC(C(=O)N1CCCCN1CCN(CC1)c1ncccn1)(c1ccccc1)c1ccccc1 InChI=1S/C28H31N5O2/c34-25-22-28(23-10-3-1-4-11-23,24-12-5-2-6-13-24)26(35)33(25)17-8-7-16-31-18-20-32(21-19-31)27-29-14-9-15-30-27/h1-6,9-15H,7-8,16-22H2 IFVHVXAOZIGOLZ-UHFFFAOYSA-N 50019438 3,3-Diphenyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-pyrrolidine-2,5-dione::CHEMBL285878 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476591 103930393 CHEMBL285878 ZINC29250415 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747721 O=C1CC2(CCCc3ccccc23)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C25H31N5O2/c31-22-19-25(10-5-8-20-7-1-2-9-21(20)25)23(32)30(22)14-4-3-13-28-15-17-29(18-16-28)24-26-11-6-12-27-24/h1-2,6-7,9,11-12H,3-5,8,10,13-19H2 QRCTZUFFXMTQDP-UHFFFAOYSA-N 50367359 CHEMBL1202533 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367359&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476612 160846461 CHEMBL1202533 ZINC29245395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747722 CC1(CC(=O)N(CCCCN2CCN(CC2)c2nsc3ccccc23)C1=O)c1ccc(F)cc1 InChI=1S/C26H29FN4O2S/c1-26(19-8-10-20(27)11-9-19)18-23(32)31(25(26)33)13-5-4-12-29-14-16-30(17-15-29)24-21-6-2-3-7-22(21)34-28-24/h2-3,6-11H,4-5,12-18H2,1H3 QJJHAAPWLZCIHS-UHFFFAOYSA-N 50019439 1-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-(4-fluoro-phenyl)-3-methyl-pyrrolidine-2,5-dione::CHEMBL417685 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476610 103930394 CHEMBL417685 ZINC29248370 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747723 CC1(C)CC(=O)N(CCCCN2CCN(CC2)c2ncccn2)C(=O)C1 InChI=1S/C19H29N5O2/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18/h5-7H,3-4,8-15H2,1-2H3 QOIGKGMMAGJZNZ-UHFFFAOYSA-N 50005132 4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-piperidine-2,6-dione::4,4-Dimethyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-piperidine-2,6-dione (Gepirone)::CHEMBL1204187::CHEMBL284092::GEPIRONE::gepiron ER D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005132&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55191 103918678 CHEMBL1204187CHEMBL284092 ZINC02021499 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747724 [O-][N+](=O)c1ccc2C(=O)N(CCCCN3CCN(CC3)c3ncccc3C#N)C(=O)c2c1 InChI=1S/C22H22N6O4/c23-15-16-4-3-7-24-20(16)26-12-10-25(11-13-26)8-1-2-9-27-21(29)18-6-5-17(28(31)32)14-19(18)22(27)30/h3-7,14H,1-2,8-13H2 LNWAITLAZHDAIV-UHFFFAOYSA-N 50367360 CHEMBL1202538 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367360&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476622 160846462 CHEMBL1202538 ZINC29308527 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747725 CSc1nc(ncc1F)N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C21H24FN5O2S/c1-30-18-17(22)14-23-21(24-18)26-12-10-25(11-13-26)8-4-5-9-27-19(28)15-6-2-3-7-16(15)20(27)29/h2-3,6-7,14H,4-5,8-13H2,1H3 MYLPTQJEYWFYHX-UHFFFAOYSA-N 50367361 CHEMBL1202537 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367361&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476624 160846463 CHEMBL1202537 ZINC29308521 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50747726 CC1(CC(=O)N(CCCCN2CCN(CC2)c2ncccn2)C1=O)c1ccc(F)cc1 InChI=1S/C23H28FN5O2/c1-23(18-5-7-19(24)8-6-18)17-20(30)29(21(23)31)12-3-2-11-27-13-15-28(16-14-27)22-25-9-4-10-26-22/h4-10H,2-3,11-17H2,1H3 ZFSXTHDCRMCHDS-UHFFFAOYSA-N 50019440 3-(4-Fluoro-phenyl)-3-methyl-1-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-pyrrolidine-2,5-dione::CHEMBL35742 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00158a026 10.7270/Q2319WGB 2874226 New, JS; Yevich, JP; Eison, MS; Taylor, DP; Eison, AS; Riblet, LA; VanderMaelen, CP; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13476597 103930395 CHEMBL35742 ZINC29243829 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50749640 Clc1ccccc1[C@@H]1CN2CCC[C@@H]2c2ccccc12 InChI=1S/C18H18ClN/c19-17-9-4-3-7-14(17)16-12-20-11-5-10-18(20)15-8-2-1-6-13(15)16/h1-4,6-9,16,18H,5,10-12H2/t16-,18-/m1/s1 KWMNBUDYCCTHHL-SJLPKXTDSA-N 50367551 CHEMBL1743803 D(2) dopamine receptor Rattus norvegicus 415 ChEMBL 10.1021/jm00391a028 10.7270/Q2D50NJ3 3039136 Maryanoff, BE; McComsey, DF; Gardocki, JF; Shank, RP; Costanzo, MJ; Nortey, SO; Schneider, CR; Setler, PE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367551&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126060 160846653 CHEMBL1743803 ZINC06117518 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50749669 CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12 InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3 GDLIGKIOYRNHDA-UHFFFAOYSA-N 77970 3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-1-propanamine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine;hydrochloride::3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-dimethyl-amine;hydrochloride::CHLORIMIPRAMINE::CLOMIPRAMINE::CLOMIPRAMINE HYDROCHLORIDE::CLOMIPRIMINE::MLS000028511::SMR000058295::cid_68539::med.21724, Compound Clomipramine D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1021/jm00391a028 10.7270/Q2D50NJ3 3039136 Maryanoff, BE; McComsey, DF; Gardocki, JF; Shank, RP; Costanzo, MJ; Nortey, SO; Schneider, CR; Setler, PE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77970&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search CXX 4MMA,2QEI,6G9I,2Q6H 2801 252654733 3755 DB01242 C06918 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751513 O=C1C2C(C3C=CC2C2CC32)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C23H29N5O2/c29-21-19-15-4-5-16(18-14-17(15)18)20(19)22(30)28(21)9-2-1-8-26-10-12-27(13-11-26)23-24-6-3-7-25-23/h3-7,15-20H,1-2,8-14H2 CHKSPZZCBQWTHT-UHFFFAOYSA-N 50367720 CHEMBL1202504 D(2) dopamine receptor Rattus norvegicus 488 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367720&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086451 160846822 CHEMBL1202504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751516 Clc1cncc(n1)N1CCN(CCCCN2C(=O)C3C(C4CCCCC3C=C4)C2=O)CC1 InChI=1S/C24H32ClN5O2/c25-19-15-26-16-20(27-19)29-13-11-28(12-14-29)9-3-4-10-30-23(31)21-17-5-1-2-6-18(8-7-17)22(21)24(30)32/h7-8,15-18,21-22H,1-6,9-14H2 LTHUIJKIRBJVAY-UHFFFAOYSA-N 50020116 4-[4-(6'-Chloro-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-butyl]-4-aza-tricyclo[5.4.2.0*2,6*]tridec-12-ene-3,5-dione;Hydrochloride::CHEMBL412258 D(2) dopamine receptor Rattus norvegicus 345 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020116&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086511 103931039 CHEMBL412258 ZINC34224145 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751519 Clc1cncc(n1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CCC43)C2=O)CC1 InChI=1S/C24H30ClN5O2/c25-19-13-26-14-20(27-19)29-11-9-28(10-12-29)7-1-2-8-30-23(31)21-17-5-6-18(22(21)24(30)32)16-4-3-15(16)17/h5-6,13-18,21-22H,1-4,7-12H2 RSTBAYLBZBFSKD-UHFFFAOYSA-N 50020113 4-{4-[4-(6-chloro-2-pyrazinyl)hexahydro-1-pyrazinyl]butyl}-4-azatetracyclo[5.4.2.02,6.08,11]tridec-12-ene-3,5-dione;Hydrochloride::CHEMBL284203 D(2) dopamine receptor Rattus norvegicus 413 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020113&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086495 103931036 CHEMBL284203 ZINC34224140 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751522 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 119 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751525 O=C1C2C3CC(C=C3)C2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H27N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3-7,15-18H,1-2,8-14H2 JVHAASOSSONHOU-UHFFFAOYSA-N 50020123 4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione;C4H4O4::CHEMBL28352 D(2) dopamine receptor Rattus norvegicus 248 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020123&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086439 103931046 CHEMBL28352 ZINC34224122 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751526 Clc1ccc(nn1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CC43)C2=O)CC1 InChI=1S/C23H28ClN5O2/c24-18-5-6-19(26-25-18)28-11-9-27(10-12-28)7-1-2-8-29-22(30)20-14-3-4-15(17-13-16(14)17)21(20)23(29)31/h3-6,14-17,20-21H,1-2,7-13H2 VUPXZFYWVQJPTN-UHFFFAOYSA-N 50020125 4-{4-[4-(6-chloro-3-pyridazinyl)hexahydro-1-pyrazinyl]butyl}-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-ene-3,5-dione;Hydrochloride::CHEMBL29218 D(2) dopamine receptor Rattus norvegicus 2334 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020125&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086454 103931048 CHEMBL29218 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751527 Clc1cncc(n1)N1CCN(CCCCN2C(=O)C3C(C4CCC3C3CCC43)C2=O)CC1 InChI=1S/C24H32ClN5O2/c25-19-13-26-14-20(27-19)29-11-9-28(10-12-29)7-1-2-8-30-23(31)21-17-5-6-18(22(21)24(30)32)16-4-3-15(16)17/h13-18,21-22H,1-12H2 ZCZUBGDGYWIBGQ-UHFFFAOYSA-N 50020122 4-{4-[4-(6-chloro-2-pyrazinyl)hexahydro-1-pyrazinyl]butyl}-4-azatetracyclo[5.4.2.02,6.08,11]tridecane-3,5-dione;Hydrochloride::CHEMBL28406 D(2) dopamine receptor Rattus norvegicus 65 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020122&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086508 103931045 CHEMBL28406 ZINC36187773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751529 Clc1cncc(n1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CC43)C2=O)CC1 InChI=1S/C23H28ClN5O2/c24-18-12-25-13-19(26-18)28-9-7-27(8-10-28)5-1-2-6-29-22(30)20-14-3-4-15(17-11-16(14)17)21(20)23(29)31/h3-4,12-17,20-21H,1-2,5-11H2 UYKWDOHZJVLLMU-UHFFFAOYSA-N 50020124 4-{4-[4-(6-chloro-2-pyrazinyl)hexahydro-1-pyrazinyl]butyl}-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-ene-3,5-dione;Hydrochloride::CHEMBL29155 D(2) dopamine receptor Rattus norvegicus 690 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020124&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9803367 103931047 CHEMBL29155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751530 O=C1C2C(C3CCC2C2CC32)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C23H31N5O2/c29-21-19-15-4-5-16(18-14-17(15)18)20(19)22(30)28(21)9-2-1-8-26-10-12-27(13-11-26)23-24-6-3-7-25-23/h3,6-7,15-20H,1-2,4-5,8-14H2 ORIMOIJEOWEROT-UHFFFAOYSA-N 50367723 CHEMBL1202494 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367723&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086466 160846825 CHEMBL1202494 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751536 O=C1C2C(C3CCC2C2CCC32)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C24H33N5O2/c30-22-20-18-6-7-19(17-5-4-16(17)18)21(20)23(31)29(22)11-2-1-10-27-12-14-28(15-13-27)24-25-8-3-9-26-24/h3,8-9,16-21H,1-2,4-7,10-15H2 PJULOFHLHHETAD-UHFFFAOYSA-N 50367721 CHEMBL1202512 D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9802404 160846823 CHEMBL1202512 ZINC36187765 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757474 CSc1cccc(c1)N1CCN(CCCON2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C22H25N3O3S/c1-29-18-7-4-6-17(16-18)24-13-11-23(12-14-24)10-5-15-28-25-21(26)19-8-2-3-9-20(19)22(25)27/h2-4,6-9,16H,5,10-15H2,1H3 ZENCDLVFNDSOEU-UHFFFAOYSA-N 50007479 2-{3-[4-(3-Methylsulfanyl-phenyl)-piperazin-1-yl]-propoxy}-isoindole-1,3-dione::CHEMBL10194 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280598 103920754 CHEMBL10194 ZINC13820886 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763768 COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29) DCSUBABJRXZOMT-UHFFFAOYSA-N 50005836 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide::4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::CHEMBL560739::CISAPRIDE::PROPULSID::US10167299, Cisapride::US10800776, Example Cisapride::US9221790, Cisapride::cid_5311047 D(2) dopamine receptor Rattus norvegicus 227 ChEMBL 10.1021/jm00086a019 10.7270/Q2CC11B3 1573641 Flynn, DL; Zabrowski, DL; Becker, DP; Nosal, R; Villamil, CI; Gullikson, GW; Moummi, C; Yang, DC Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005836&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2769 103919261 CHEMBL560739 240 C06910 ZINC03830564 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763790 CC(C)n1c2ccccc2n(C(=O)CC2CC3CCC(C2)N3C)c1=O InChI=1S/C20H27N3O2/c1-13(2)22-17-6-4-5-7-18(17)23(20(22)25)19(24)12-14-10-15-8-9-16(11-14)21(15)3/h4-7,13-16H,8-12H2,1-3H3 DKNCSSURJOYOSO-UHFFFAOYSA-N 50005834 1-Isopropyl-3-[2-(8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-acetyl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL38041 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00086a019 10.7270/Q2CC11B3 1573641 Flynn, DL; Zabrowski, DL; Becker, DP; Nosal, R; Villamil, CI; Gullikson, GW; Moummi, C; Yang, DC Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005834&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283512 103919259 CHEMBL38041 ZINC29308484 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763801 COc1cc(N)c(Cl)cc1C(=O)NC[C@@H]1CCN2CCC[C@@H]12 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-9-10-4-6-20-5-2-3-14(10)20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21)/t10-,14-/m0/s1 GAYSOZKZPOVDSB-HZMBPMFUSA-N 50005833 (exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-pyrrolizin-1-ylmethyl)-benzamide::4-Amino-5-chloro-N-(hexahydro-pyrrolizin-2-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-N-[(1S,7aS)-1-(hexahydro-pyrrolizin-1-yl)methyl]-2-methoxy-benzamide::4-amino-5-chloro-N-[(1S-cis-hexahydro-1H-pyrrolizin-1-yl)-methyl]-2-methoxybenzenecarboxamide::CHEMBL34291::SC-53116::SC49518::SC53116 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00086a019 10.7270/Q2CC11B3 1573641 Flynn, DL; Zabrowski, DL; Becker, DP; Nosal, R; Villamil, CI; Gullikson, GW; Moummi, C; Yang, DC Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005833&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 132337 103919258 CHEMBL34291 238 ZINC03790774 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763804 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 113 ChEMBL 10.1021/jm00086a019 10.7270/Q2CC11B3 1573641 Flynn, DL; Zabrowski, DL; Becker, DP; Nosal, R; Villamil, CI; Gullikson, GW; Moummi, C; Yang, DC Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763809 COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CN2CCC1CC2 InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20)/t13-/m0/s1 FEROPKNOYKURCJ-ZDUSSCGKSA-N 50031475 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-((R)-methoxy)-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(R)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxy-benzamide::CHEMBL27846::ZACOPRIDE,S D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00086a019 10.7270/Q2CC11B3 1573641 Flynn, DL; Zabrowski, DL; Becker, DP; Nosal, R; Villamil, CI; Gullikson, GW; Moummi, C; Yang, DC Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50031475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50031475&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9819593 103940106 CHEMBL27846 2288 ZINC00000848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50763817 COc1cc(N)c(Cl)cc1C(=O)N[C@]12CN3CC1C2CC3 InChI=1S/C15H18ClN3O2/c1-21-13-5-12(17)11(16)4-8(13)14(20)18-15-7-19-3-2-9(15)10(15)6-19/h4-5,9-10H,2-3,6-7,17H2,1H3,(H,18,20)/t9?,10?,15-/m1/s1 VQZUPPBUGNMRJI-HKJQSTPSSA-N 50368604 CHEMBL1907770 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00086a019 10.7270/Q2CC11B3 1573641 Flynn, DL; Zabrowski, DL; Becker, DP; Nosal, R; Villamil, CI; Gullikson, GW; Moummi, C; Yang, DC Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368604&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57391435 160847706 CHEMBL1907770 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50749696 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.750000 ChEMBL 10.1021/jm00391a028 10.7270/Q2D50NJ3 3039136 Maryanoff, BE; McComsey, DF; Gardocki, JF; Shank, RP; Costanzo, MJ; Nortey, SO; Schneider, CR; Setler, PE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50749698 C1C[C@H]2N(C1)C[C@@H](c1ccccc1)c1ccccc21 InChI=1S/C18H19N/c1-2-7-14(8-3-1)17-13-19-12-6-11-18(19)16-10-5-4-9-15(16)17/h1-5,7-10,17-18H,6,11-13H2/t17-,18+/m0/s1 KJHWRRVSXANANB-ZWKOTPCHSA-N 50021874 6-Phenyl-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline;C4H4O4::6-Phenyl-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline;HBr::6-Phenyl-1,2,3,5,6,10b-hexahydro-pyrrolo[2,1-a]isoquinoline;HCl::CHEMBL35184 D(2) dopamine receptor Rattus norvegicus 875 ChEMBL 10.1021/jm00391a028 10.7270/Q2D50NJ3 3039136 Maryanoff, BE; McComsey, DF; Gardocki, JF; Shank, RP; Costanzo, MJ; Nortey, SO; Schneider, CR; Setler, PE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135949 103932564 CHEMBL35184 ZINC06116281 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50749727 Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H YNPFMWCWRVTGKJ-UHFFFAOYSA-N 31005 2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine::MIANSERIN HYDROCHLORIDE::MLS000069681::SMR000058472::cid_68551 D(2) dopamine receptor Rattus norvegicus 828 ChEMBL 10.1021/jm00391a028 10.7270/Q2D50NJ3 3039136 Maryanoff, BE; McComsey, DF; Gardocki, JF; Shank, RP; Costanzo, MJ; Nortey, SO; Schneider, CR; Setler, PE TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31005&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68551 242052839 ZINC00000504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751543 O=C1C2C(C3C=CC2C2C=CC32)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C24H29N5O2/c30-22-20-18-6-7-19(17-5-4-16(17)18)21(20)23(31)29(22)11-2-1-10-27-12-14-28(15-13-27)24-25-8-3-9-26-24/h3-9,16-21H,1-2,10-15H2 AERLHOTUXIJQFV-UHFFFAOYSA-N 50367729 CHEMBL1204094 D(2) dopamine receptor Rattus norvegicus 345 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367729&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9804072 160846831 CHEMBL1204094 ZINC36187775 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751546 CC(C)=C1C2C=CC1C1C2C(=O)N(CCCCN2CCN(CC2)c2cncc(Cl)n2)C1=O InChI=1S/C24H30ClN5O2/c1-15(2)20-16-5-6-17(20)22-21(16)23(31)30(24(22)32)8-4-3-7-28-9-11-29(12-10-28)19-14-26-13-18(25)27-19/h5-6,13-14,16-17,21-22H,3-4,7-12H2,1-2H3 NKIPFKDLBWSFQM-UHFFFAOYSA-N 50020136 4-[4-(6'-Chloro-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl)-butyl]-10-isopropylidene-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione;Hydrochloride::CHEMBL281215 D(2) dopamine receptor Rattus norvegicus 968 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020136&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086449 103931059 CHEMBL281215 ZINC28770976 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751548 Clc1nccnc1N1CCN(CCCCN2C(=O)C3C(C4CCC3C3CCC43)C2=O)CC1 InChI=1S/C24H32ClN5O2/c25-21-22(27-8-7-26-21)29-13-11-28(12-14-29)9-1-2-10-30-23(31)19-17-5-6-18(20(19)24(30)32)16-4-3-15(16)17/h7-8,15-20H,1-6,9-14H2 GNVHTRWGQROSFM-UHFFFAOYSA-N 50020137 4-{4-[4-(3-chloro-2-pyrazinyl)hexahydro-1-pyrazinyl]butyl}-4-azatetracyclo[5.4.2.02,6.08,11]tridecane-3,5-dione;Hydrochloride::CHEMBL31319 D(2) dopamine receptor Rattus norvegicus 74 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020137&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44278574 103931060 CHEMBL31319 ZINC36093042 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751551 COc1ccccc1N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CC43)C2=O)CC1 InChI=1S/C26H33N3O3/c1-32-22-7-3-2-6-21(22)28-14-12-27(13-15-28)10-4-5-11-29-25(30)23-17-8-9-18(20-16-19(17)20)24(23)26(29)31/h2-3,6-9,17-20,23-24H,4-5,10-16H2,1H3 YNJVCNKZQNAPMV-UHFFFAOYSA-N 50367726 CHEMBL1202507 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086462 160846828 CHEMBL1202507 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751553 Clc1ccc(nn1)N1CCN(CCCCN2C(=O)C3C(C4C=CC3C3CCC43)C2=O)CC1 InChI=1S/C24H30ClN5O2/c25-19-7-8-20(27-26-19)29-13-11-28(12-14-29)9-1-2-10-30-23(31)21-17-5-6-18(22(21)24(30)32)16-4-3-15(16)17/h5-8,15-18,21-22H,1-4,9-14H2 GMXNKMCRRWILFB-UHFFFAOYSA-N 50020141 4-{4-[4-(6-chloro-3-pyridazinyl)hexahydro-1-pyrazinyl]butyl}-4-azatetracyclo[5.4.2.02,6.08,11]tridec-12-ene-3,5-dione;Hydrochloride::CHEMBL424409 D(2) dopamine receptor Rattus norvegicus 1925 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020141&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086501 103931064 CHEMBL424409 ZINC36093040 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751554 O=C1C2C(C3C=CC2C2CCC32)C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C24H31N5O2/c30-22-20-18-6-7-19(17-5-4-16(17)18)21(20)23(31)29(22)11-2-1-10-27-12-14-28(15-13-27)24-25-8-3-9-26-24/h3,6-9,16-21H,1-2,4-5,10-15H2 YHTVLSXGNORZOJ-UHFFFAOYSA-N 50367719 CHEMBL1202513 D(2) dopamine receptor Rattus norvegicus 85 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367719&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14086493 160846821 CHEMBL1202513 ZINC34224138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751560 O=C1C2CCCCC2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C20H29N5O2/c26-18-16-6-1-2-7-17(16)19(27)25(18)11-4-3-10-23-12-14-24(15-13-23)20-21-8-5-9-22-20/h5,8-9,16-17H,1-4,6-7,10-15H2 VRNLQFXRAPWSFK-UHFFFAOYSA-N 50020144 2-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-hexahydro-isoindole-1,3-dione;C4H4O4::CHEMBL28453 D(2) dopamine receptor Rattus norvegicus 374 ChEMBL 10.1021/jm00402a023 10.7270/Q2PC32Z4 2898533 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020144&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15592394 103931067 CHEMBL28453 ZINC28769997 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751635 CCN(CC)CCNC(=NOC)c1cc(Cl)c(N)cc1OC InChI=1S/C15H25ClN4O2/c1-5-20(6-2)8-7-18-15(19-22-4)11-9-12(16)13(17)10-14(11)21-3/h9-10H,5-8,17H2,1-4H3,(H,18,19) UEOPSCRGHLYAHM-UHFFFAOYSA-N 50023798 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2,N'-dimethoxy-benzamidine::CHEMBL41192 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023798&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116952 103934098 CHEMBL41192 ZINC29339640 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751636 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(=O)c1cccs1 InChI=1S/C19H24ClN3O3S/c1-3-23(4-2)8-7-22-19(25)13-10-14(20)15(21)11-17(13)26-12-16(24)18-6-5-9-27-18/h5-6,9-11H,3-4,7-8,12,21H2,1-2H3,(H,22,25) JGLQBRNLEHOENY-UHFFFAOYSA-N 50023799 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo-2-thiophen-2-yl-ethoxy)-benzamide::CHEMBL39427 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116897 103934099 CHEMBL39427 ZINC29337252 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751637 CCN1CCCCCOc2cc(N)c(Cl)cc2C(=O)NCCC1 InChI=1S/C17H26ClN3O2/c1-2-21-8-4-3-5-10-23-16-12-15(19)14(18)11-13(16)17(22)20-7-6-9-21/h11-12H,2-10,19H2,1H3,(H,20,22) WHVQUSLAQBLJHI-UHFFFAOYSA-N 50023801 3-Amino-2-chloro-11-ethyl-6,7,8,9,10,11,12,13,14,15-decahydro-5-oxa-11,15-diaza-benzocyclotetradecen-16-one::CHEMBL432681 D(2) dopamine receptor Rattus norvegicus 7.7 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286505 103934101 CHEMBL432681 ZINC29337644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751638 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC#N InChI=1S/C15H21ClN4O2/c1-3-20(4-2)7-6-19-15(21)11-9-12(16)13(18)10-14(11)22-8-5-17/h9-10H,3-4,6-8,18H2,1-2H3,(H,19,21) ZTXYPANIEPFDPQ-UHFFFAOYSA-N 50023800 4-Amino-5-chloro-2-cyanomethoxy-N-(2-diethylamino-ethyl)-benzamide::CHEMBL43352 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116886 103934100 CHEMBL43352 ZINC29341105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751639 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 565 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751641 CCN(CC)CCN(C)C(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C15H24ClN3O2/c1-5-19(6-2)8-7-18(3)15(20)11-9-12(16)13(17)10-14(11)21-4/h9-10H,5-8,17H2,1-4H3 JEUCSMQOUIJAHU-UHFFFAOYSA-N 50023803 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-N-methyl-benzamide::CHEMBL41777 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116946 103934103 CHEMBL41777 ZINC29340578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751642 COc1cc2nn[nH]c2cc1C(=O)NCC1CCCN1CC=C InChI=1S/C16H21N5O2/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20) KSEYRUGYKHXGFW-UHFFFAOYSA-N 50023804 6-Methoxy-1H-benzotriazole-5-carboxylic acid (1-allyl-pyrrolidin-2-ylmethyl)-amide::ALIZAPRIDE::CHEMBL290194 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023804&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 43008 103934104 CHEMBL290194 ZINC12503303 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751643 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC(C)C(C)O InChI=1S/C17H28ClN3O3/c1-5-21(6-2)8-7-20-17(23)13-9-14(18)15(19)10-16(13)24-12(4)11(3)22/h9-12,22H,5-8,19H2,1-4H3,(H,20,23) NDZDJUSQBJHCBF-UHFFFAOYSA-N 50023802 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-1-methyl-propoxy)-benzamide::CHEMBL289740::erythro-4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-1-methyl-propoxy)-benzamide::threo-4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-1-methyl-propoxy)-benzamide D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116911 103934102 CHEMBL289740 ZINC13885312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751644 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCC1(C)OCCO1 InChI=1S/C19H30ClN3O4/c1-4-23(5-2)8-7-22-18(24)14-12-15(20)16(21)13-17(14)25-9-6-19(3)26-10-11-27-19/h12-13H,4-11,21H2,1-3H3,(H,22,24) TUTPPMHJBJNTKW-UHFFFAOYSA-N 50023807 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethoxy]-benzamide::CHEMBL41276 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116922 103934107 CHEMBL41276 ZINC29340773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751645 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCc1ccccc1 InChI=1S/C20H26ClN3O2/c1-3-24(4-2)11-10-23-20(25)16-12-17(21)18(22)13-19(16)26-14-15-8-6-5-7-9-15/h5-9,12-13H,3-4,10-11,14,22H2,1-2H3,(H,23,25) RNDGARWUQSIOQW-UHFFFAOYSA-N 50023805 4-Amino-2-benzyloxy-5-chloro-N-(2-diethylamino-ethyl)-benzamide::CHEMBL39623 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 211484 103934105 CHEMBL39623 ZINC03616751 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751646 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCC=C InChI=1S/C17H26ClN3O2/c1-4-7-10-23-16-12-15(19)14(18)11-13(16)17(22)20-8-9-21(5-2)6-3/h4,11-12H,1,5-10,19H2,2-3H3,(H,20,22) JZXNJMALFOJSIJ-UHFFFAOYSA-N 50023808 4-Amino-2-but-3-enyloxy-5-chloro-N-(2-diethylamino-ethyl)-benzamide::CHEMBL39556 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116884 103934108 CHEMBL39556 ZINC29329018 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751647 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC1CCCC[C@H]1O InChI=1S/C19H30ClN3O3/c1-3-23(4-2)10-9-22-19(25)13-11-14(20)15(21)12-18(13)26-17-8-6-5-7-16(17)24/h11-12,16-17,24H,3-10,21H2,1-2H3,(H,22,25)/t16-,17?/m1/s1 KJZIHOYWZYDQEJ-TZHYSIJRSA-N 50023806 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-cyclohexyloxy)-benzamide::CHEMBL36924 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286134 103934106 CHEMBL36924 ZINC29322620 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751648 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1O InChI=1S/C13H20ClN3O2/c1-3-17(4-2)6-5-16-13(19)9-7-10(14)11(15)8-12(9)18/h7-8,18H,3-6,15H2,1-2H3,(H,16,19) HPSMMIJTHMWCGC-UHFFFAOYSA-N 50023811 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-hydroxy-benzamide::CHEMBL43695 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817332 103934111 CHEMBL43695 ZINC04213841 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751649 CCN(CC)CCCS(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H23ClN2O2S/c1-4-17(5-2)7-6-8-20(18)14-9-11(15)12(16)10-13(14)19-3/h9-10H,4-8,16H2,1-3H3 DUHWMNNAAIDWPF-UHFFFAOYSA-N 50023812 2-Chloro-4-(3-diethylamino-propane-1-sulfinyl)-5-methoxy-phenylamine::CHEMBL41139 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023812&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116956 103934112 CHEMBL41139 ZINC29339638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751651 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCO InChI=1S/C15H24ClN3O3/c1-3-19(4-2)6-5-18-15(21)11-9-12(16)13(17)10-14(11)22-8-7-20/h9-10,20H,3-8,17H2,1-2H3,(H,18,21) JYSBWWBKJZCBFN-UHFFFAOYSA-N 50023814 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-ethoxy)-benzamide::CHEMBL290027 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116907 103934114 CHEMBL290027 ZINC29338927 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755031 CCCc1cc(OC)c(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1OC InChI=1S/C20H32N2O4/c1-6-9-14-12-16(24-3)19(26-5)17(18(14)25-4)20(23)21-13-15-10-8-11-22(15)7-2/h12,15H,6-11,13H2,1-5H3,(H,21,23)/t15-/m0/s1 PQQXQOJIDLXQOC-HNNXBMFYSA-N 50368058 CHEMBL1907703 D(2) dopamine receptor Rattus norvegicus 2960 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368058&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668279 160847160 CHEMBL1907703 ZINC34343057 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755032 CCN1CCC[C@H]1CNC(=O)c1c(O)c(OC)cc(CC)c1OC InChI=1S/C18H28N2O4/c1-5-12-10-14(23-3)16(21)15(17(12)24-4)18(22)19-11-13-8-7-9-20(13)6-2/h10,13,21H,5-9,11H2,1-4H3,(H,19,22)/t13-/m0/s1 WTKIGCPVTZEDQY-ZDUSSCGKSA-N 50368059 CHEMBL1907697 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368059&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668302 160847161 CHEMBL1907697 ZINC34343072 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755035 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.330000 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755037 COc1cc(Br)c(OC)c(C(=O)NC[C@@H]2CCCN2CC=C)c1O InChI=1S/C17H23BrN2O4/c1-4-7-20-8-5-6-11(20)10-19-17(22)14-15(21)13(23-2)9-12(18)16(14)24-3/h4,9,11,21H,1,5-8,10H2,2-3H3,(H,19,22)/t11-/m0/s1 QSMBPKWYIRFETR-NSHDSACASA-N 50368061 CHEMBL1907694 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368061&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668306 160847163 CHEMBL1907694 ZINC34343076 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755038 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755040 Cl.CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(N)c1OC InChI=1S/C15H22BrN3O3.ClH/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2;/h7,9,20H,3-6,8,17H2,1-2H3,(H,18,21);1H/t9-;/m0./s1 NKFJWDRUXGPBEM-FVGYRXGTSA-N 50010640 (S)-3-Amino-5-bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide; hydrochloride::CHEMBL3085402 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010640&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76317001 103923414 CHEMBL3085402 ZINC34343081 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755043 COc1cc(Br)c(O)c(C(=O)NC[C@@H]2CCCN2CC=C)c1OC InChI=1S/C17H23BrN2O4/c1-4-7-20-8-5-6-11(20)10-19-17(22)14-15(21)12(18)9-13(23-2)16(14)24-3/h4,9,11,21H,1,5-8,10H2,2-3H3,(H,19,22)/t11-/m0/s1 GKZQXGJWJBZSMC-NSHDSACASA-N 50368063 CHEMBL1907700 D(2) dopamine receptor Rattus norvegicus 2.3 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368063&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668304 160847165 CHEMBL1907700 ZINC34343074 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755046 Cl.CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(O)c1OC InChI=1S/C15H21BrN2O4.ClH/c1-3-18-6-4-5-9(18)8-17-15(21)12-13(20)10(16)7-11(19)14(12)22-2;/h7,9,19-20H,3-6,8H2,1-2H3,(H,17,21);1H/t9-;/m0./s1 ACETUMXAYKNQPZ-FVGYRXGTSA-N 50010644 (S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,5-dihydroxy-6-methoxy-benzamide; hydrochloride::CHEMBL3085403 D(2) dopamine receptor Rattus norvegicus 1.9 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668322 103923418 CHEMBL3085403 ZINC34343086 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755047 CCN1CCC[C@H]1CNC(=O)c1c(OC)c(Cl)cc(OC)c1OC InChI=1S/C17H25ClN2O4/c1-5-20-8-6-7-11(20)10-19-17(21)14-15(23-3)12(18)9-13(22-2)16(14)24-4/h9,11H,5-8,10H2,1-4H3,(H,19,21)/t11-/m0/s1 MPKKCEUANNGJTC-NSHDSACASA-N 50368064 CHEMBL1907701 D(2) dopamine receptor Rattus norvegicus 420 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368064&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668272 160847166 CHEMBL1907701 ZINC34343052 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755049 CCN1CCC[C@H]1CNC(=O)c1c(OC)c(Br)cc(OC)c1OC InChI=1S/C17H25BrN2O4/c1-5-20-8-6-7-11(20)10-19-17(21)14-15(23-3)12(18)9-13(22-2)16(14)24-4/h9,11H,5-8,10H2,1-4H3,(H,19,21)/t11-/m0/s1 OQOZGNFSDYSQCV-NSHDSACASA-N 50368066 CHEMBL1907699 D(2) dopamine receptor Rattus norvegicus 1750 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368066&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668274 160847168 CHEMBL1907699 ZINC34343054 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755053 CCN1CCC[C@H]1CNC(=O)c1c(O)c(OC)ccc1OC InChI=1S/C16H24N2O4/c1-4-18-9-5-6-11(18)10-17-16(20)14-12(21-2)7-8-13(22-3)15(14)19/h7-8,11,19H,4-6,9-10H2,1-3H3,(H,17,20)/t11-/m0/s1 KLVUHGFKRXLSDU-NSHDSACASA-N 50368068 CHEMBL1907696 D(2) dopamine receptor Rattus norvegicus 205 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368068&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668286 160847170 CHEMBL1907696 ZINC34343063 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755054 CCN1CCC[C@H]1CNC(=O)c1c(O)c(OC)cc(Cl)c1OC InChI=1S/C16H23ClN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)12(22-2)8-11(17)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 PVTGDSOBBMPZMQ-JTQLQIEISA-N 50368069 CHEMBL1907698 D(2) dopamine receptor Rattus norvegicus 71 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368069&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668291 160847171 CHEMBL1907698 ZINC34343067 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755055 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.120000 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755056 CCN1CCC[C@H]1CNC(=O)c1c(N)c(Br)cc(OC)c1OC InChI=1S/C16H24BrN3O3/c1-4-20-7-5-6-10(20)9-19-16(21)13-14(18)11(17)8-12(22-2)15(13)23-3/h8,10H,4-7,9,18H2,1-3H3,(H,19,21)/t10-/m0/s1 JVZAYLSEXNKOFB-JTQLQIEISA-N 50368070 CHEMBL1907693 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368070&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10317969 160847172 CHEMBL1907693 ZINC34223419 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755057 CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(O)c1OC InChI=1S/C15H22N2O4/c1-3-17-8-4-5-10(17)9-16-15(20)13-11(18)6-7-12(19)14(13)21-2/h6-7,10,18-19H,3-5,8-9H2,1-2H3,(H,16,20)/t10-/m0/s1 FRWARWDIMMRUPR-JTQLQIEISA-N 50368071 CHEMBL1907691 D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368071&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668320 160847173 CHEMBL1907691 ZINC34343085 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755061 CCN1CCC[C@@H]1CNC(=O)c1c(O)c(OC)cc(Br)c1OC InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)12(22-2)8-11(17)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m1/s1 UFZPFNGITSAOBL-SNVBAGLBSA-N 50368072 CHEMBL1907914 D(2) dopamine receptor Rattus norvegicus 6170 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368072&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668297 160847174 CHEMBL1907914 ZINC34343068 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755063 CCN1CCCC1CNC(=O)c1c(OC)c(CC)cc(OC)c1OC InChI=1S/C19H30N2O4/c1-6-13-11-15(23-3)18(25-5)16(17(13)24-4)19(22)20-12-14-9-8-10-21(14)7-2/h11,14H,6-10,12H2,1-5H3,(H,20,22) CNYFTYULLUBARK-UHFFFAOYSA-N 50010655 (S)-3-Ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,5,6-trimethoxy-benzamide::CHEMBL16252 D(2) dopamine receptor Rattus norvegicus 820 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010655&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668276 103923429 CHEMBL16252 ZINC34343056 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757479 OC1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H32N4O3S/c28-20-16-23(8-3-4-9-23)17-21(29)27(20)30-15-5-10-25-11-13-26(14-12-25)22-18-6-1-2-7-19(18)31-24-22/h1-2,6-7,20,28H,3-5,8-17H2 BDMMVEQEGALIHG-UHFFFAOYSA-N 50007483 8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-propoxy]-9-hydroxy-8-aza-spiro[4.5]decan-7-one::CHEMBL274334 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280605 103920758 CHEMBL274334 ZINC13820864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757483 COc1ccccc1N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C23H33N3O4/c1-29-20-8-3-2-7-19(20)25-14-12-24(13-15-25)11-6-16-30-26-21(27)17-23(18-22(26)28)9-4-5-10-23/h2-3,7-8H,4-6,9-18H2,1H3 RMVBZZIASSXTEW-UHFFFAOYSA-N 50007480 8-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decane-7,9-dione(HCl0.5H2O)::CHEMBL10366 D(2) dopamine receptor Rattus norvegicus 930 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007480&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14500867 103920755 CHEMBL10366 ZINC13820852 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757484 O=C1N(OCCCN2CCN(CC2)c2ccc3ccccc3n2)C(=O)c2ccccc12 InChI=1S/C24H24N4O3/c29-23-19-7-2-3-8-20(19)24(30)28(23)31-17-5-12-26-13-15-27(16-14-26)22-11-10-18-6-1-4-9-21(18)25-22/h1-4,6-11H,5,12-17H2 BPSOSTBMZBDVNS-UHFFFAOYSA-N 50007487 2-[3-(4-Quinolin-2-yl-piperazin-1-yl)-propoxy]-isoindole-1,3-dione::CHEMBL274566 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007487&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280600 103920762 CHEMBL274566 ZINC13820882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757486 O=C1CC2(CCCC2)CC(=O)N1OCCN1CCN(CC1)c1ncccn1 InChI=1S/C19H27N5O3/c25-16-14-19(4-1-2-5-19)15-17(26)24(16)27-13-12-22-8-10-23(11-9-22)18-20-6-3-7-21-18/h3,6-7H,1-2,4-5,8-15H2 KWNSXONJJXBOFN-UHFFFAOYSA-N 50007489 8-[2-(4-Pyrimidin-2-yl-piperazin-1-yl)-ethoxy]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL273505 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007489&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4742679 103920764 CHEMBL273505 ZINC53070586 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757487 Cc1cccc(c1)N1CCN(CCCON2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C22H25N3O3/c1-17-6-4-7-18(16-17)24-13-11-23(12-14-24)10-5-15-28-25-21(26)19-8-2-3-9-20(19)22(25)27/h2-4,6-9,16H,5,10-15H2,1H3 RHECIYJIUGOBHK-UHFFFAOYSA-N 50007488 2-[3-(4-m-Tolyl-piperazin-1-yl)-propoxy]-isoindole-1,3-dione::CHEMBL264472 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3029004 103920763 CHEMBL264472 ZINC05798970 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757488 COc1ccccc1N1CCN(CCCON2CCC3(CCCC3)CC2=O)CC1 InChI=1S/C23H35N3O3/c1-28-21-8-3-2-7-20(21)25-16-14-24(15-17-25)12-6-18-29-26-13-11-23(19-22(26)27)9-4-5-10-23/h2-3,7-8H,4-6,9-19H2,1H3 VWDWRPLKHXLHAD-UHFFFAOYSA-N 50007492 8-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decan-7-one(HCl1.5H2O)::CHEMBL269458 D(2) dopamine receptor Rattus norvegicus 720 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007492&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280603 103920767 CHEMBL269458 ZINC13820873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757489 O=C1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)c1nc2ccccc2s1 InChI=1S/C23H30N4O3S/c28-20-16-23(8-3-4-9-23)17-21(29)27(20)30-15-5-10-25-11-13-26(14-12-25)22-24-18-6-1-2-7-19(18)31-22/h1-2,6-7H,3-5,8-17H2 VKCFJXPSFRUTDE-UHFFFAOYSA-N 50007490 8-[3-(4-Benzothiazol-2-yl-piperazin-1-yl)-propoxy]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL418340 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007490&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280593 103920765 CHEMBL418340 ZINC53224072 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757494 COc1ccccc1N1CCN(CCCON2C(O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C23H35N3O4/c1-29-20-8-3-2-7-19(20)25-14-12-24(13-15-25)11-6-16-30-26-21(27)17-23(18-22(26)28)9-4-5-10-23/h2-3,7-8,21,27H,4-6,9-18H2,1H3 MNMXGKPOXVZOEM-UHFFFAOYSA-N 50007495 9-Hydroxy-8-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decan-7-one::CHEMBL10640 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280606 103920770 CHEMBL10640 ZINC13820871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757498 O=C1N(OCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12 InChI=1S/C22H22N4O3S/c27-21-16-6-1-2-7-17(16)22(28)26(21)29-15-5-10-24-11-13-25(14-12-24)20-18-8-3-4-9-19(18)30-23-20/h1-4,6-9H,5,10-15H2 BNMQXFGPFVUGQY-UHFFFAOYSA-N 50007491 2-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-propoxy]-isoindole-1,3-dione::CHEMBL10546 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007491&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280599 103920766 CHEMBL10546 ZINC13820880 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757501 CSc1cccc(c1)N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C23H33N3O3S/c1-30-20-7-4-6-19(16-20)25-13-11-24(12-14-25)10-5-15-29-26-21(27)17-23(18-22(26)28)8-2-3-9-23/h4,6-7,16H,2-3,5,8-15,17-18H2,1H3 DFWFWFKGVBAJEG-UHFFFAOYSA-N 50007496 8-{3-[4-(3-Methylsulfanyl-phenyl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL10963 D(2) dopamine receptor Rattus norvegicus 4090 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007496&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280607 103920771 CHEMBL10963 ZINC13820854 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757503 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H32N4O2S/c29-21-17-24(9-3-4-10-24)18-22(30)28(21)12-6-5-11-26-13-15-27(16-14-26)23-19-7-1-2-8-20(19)31-25-23/h1-2,7-8H,3-6,9-18H2 ZFZPJDFBJFHYIV-UHFFFAOYSA-N 50007692 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL1204189::CHEMBL35057::TIOSPERONE D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55752 103920962 CHEMBL1204189CHEMBL35057 101 ZINC01915508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757505 O=C1CC2(CCCC2)CC(=O)N1OCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H28N4O3S/c27-19-15-22(7-3-4-8-22)16-20(28)26(19)29-14-13-24-9-11-25(12-10-24)21-17-5-1-2-6-18(17)30-23-21/h1-2,5-6H,3-4,7-16H2 HYIUAGVTCHMUNW-UHFFFAOYSA-N 50007497 8-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethoxy]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL268267 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4742703 103920772 CHEMBL268267 ZINC53050140 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757508 O=C1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)C1=NS(=O)(=O)c2ccccc12 InChI=1S/C23H30N4O5S/c28-20-16-23(8-3-4-9-23)17-21(29)27(20)32-15-5-10-25-11-13-26(14-12-25)22-18-6-1-2-7-19(18)33(30,31)24-22/h1-2,6-7H,3-5,8-17H2 NZLUWSOLFYRHOA-UHFFFAOYSA-N 50007499 8-{3-[4-(1,1-Dioxo-1H-1lambda*6*-benzo[d]isothiazol-3-yl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL10658 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007499&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14896472 103920774 CHEMBL10658 ZINC13820859 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757509 Clc1ccccc1N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C22H30ClN3O3/c23-18-6-1-2-7-19(18)25-13-11-24(12-14-25)10-5-15-29-26-20(27)16-22(17-21(26)28)8-3-4-9-22/h1-2,6-7H,3-5,8-17H2 RZUNPHILLASKHF-UHFFFAOYSA-N 50007485 8-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decane-7,9-dione(HCl)::CHEMBL10880 D(2) dopamine receptor Rattus norvegicus 680 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007485&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14896471 103920760 CHEMBL10880 ZINC13820850 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757517 O=C1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)c1ncccn1 InChI=1S/C20H29N5O3/c26-17-15-20(5-1-2-6-20)16-18(27)25(17)28-14-4-9-23-10-12-24(13-11-23)19-21-7-3-8-22-19/h3,7-8H,1-2,4-6,9-16H2 IEYBMRSDSCBGBL-UHFFFAOYSA-N 50007493 8-[3-(4-Pyrimidin-2-yl-piperazin-1-yl)-propoxy]-8-aza-spiro[4.5]decane-7,9-dione(HCl0.5H2O)::CHEMBL274306 D(2) dopamine receptor Rattus norvegicus 2000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280591 103920768 CHEMBL274306 ZINC53059320 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757519 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757522 Clc1cccc(c1)N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C22H30ClN3O3/c23-18-5-3-6-19(15-18)25-12-10-24(11-13-25)9-4-14-29-26-20(27)16-22(17-21(26)28)7-1-2-8-22/h3,5-6,15H,1-2,4,7-14,16-17H2 QNHIGOFQRMNMEM-UHFFFAOYSA-N 50007494 8-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decane-7,9-dione(HCl0.5H2O)::CHEMBL10821 D(2) dopamine receptor Rattus norvegicus 2800 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007494&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280584 103920769 CHEMBL10821 ZINC13820846 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757527 O=C1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)c1ccc2ccccc2n1 InChI=1S/C25H32N4O3/c30-23-18-25(10-3-4-11-25)19-24(31)29(23)32-17-5-12-27-13-15-28(16-14-27)22-9-8-20-6-1-2-7-21(20)26-22/h1-2,6-9H,3-5,10-19H2 BYFYQDNROZOLIH-UHFFFAOYSA-N 50007503 8-[3-(4-Quinolin-2-yl-piperazin-1-yl)-propoxy]-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL430329 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280594 103920778 CHEMBL430329 ZINC13820857 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757530 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757531 Cc1cccc(c1)N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C23H33N3O3/c1-19-6-4-7-20(16-19)25-13-11-24(12-14-25)10-5-15-29-26-21(27)17-23(18-22(26)28)8-2-3-9-23/h4,6-7,16H,2-3,5,8-15,17-18H2,1H3 RPXBMXISYUBWDU-UHFFFAOYSA-N 50007484 8-[3-(4-m-Tolyl-piperazin-1-yl)-propoxy]-8-aza-spiro[4.5]decane-7,9-dione(HCl0.5H2O)::CHEMBL10875 D(2) dopamine receptor Rattus norvegicus 3700 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007484&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280585 103920759 CHEMBL10875 ZINC01542275 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757533 FC(F)(F)c1cccc(c1)N1CCN(CCCON2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C23H30F3N3O3/c24-23(25,26)18-5-3-6-19(15-18)28-12-10-27(11-13-28)9-4-14-32-29-20(30)16-22(17-21(29)31)7-1-2-8-22/h3,5-6,15H,1-2,4,7-14,16-17H2 KBFRCNWYVQHAIH-UHFFFAOYSA-N 50007505 8-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decane-7,9-dione(HCl)::CHEMBL10355 D(2) dopamine receptor Rattus norvegicus 2900 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280588 103920780 CHEMBL10355 ZINC01542277 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757536 O=C1CC2(CCCC2)CCN1OCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H32N4O2S/c28-21-18-23(8-3-4-9-23)10-12-27(21)29-17-5-11-25-13-15-26(16-14-25)22-19-6-1-2-7-20(19)30-24-22/h1-2,6-7H,3-5,8-18H2 AAKNNWSCDBHEJI-UHFFFAOYSA-N 50007498 8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-propoxy]-8-aza-spiro[4.5]decan-7-one(HCl)::CHEMBL269176 D(2) dopamine receptor Rattus norvegicus 170 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007498&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280601 103920773 CHEMBL269176 ZINC13820867 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757537 Clc1cccc(c1)N1CCN(CCCON2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C21H22ClN3O3/c22-16-5-3-6-17(15-16)24-12-10-23(11-13-24)9-4-14-28-25-20(26)18-7-1-2-8-19(18)21(25)27/h1-3,5-8,15H,4,9-14H2 CPKTXABUZUYKSY-UHFFFAOYSA-N 50007504 2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propoxy}-isoindole-1,3-dione::CHEMBL10623 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007504&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3028982 103920779 CHEMBL10623 ZINC05800314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757538 FC(F)(F)c1cccc(c1)N1CCN(CCCON2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C22H22F3N3O3/c23-22(24,25)16-5-3-6-17(15-16)27-12-10-26(11-13-27)9-4-14-31-28-20(29)18-7-1-2-8-19(18)21(28)30/h1-3,5-8,15H,4,9-14H2 CEFKGZFOFOYUQV-UHFFFAOYSA-N 50007501 2-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-propoxy}-isoindole-1,3-dione(HCl)::CHEMBL10682 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007501&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280595 103920776 CHEMBL10682 ZINC13820876 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757539 Cc1cccc(N2CCN(CCCON3C(=O)CC4(CCCC4)CC3=O)CC2)c1C InChI=1S/C24H35N3O3/c1-19-7-5-8-21(20(19)2)26-14-12-25(13-15-26)11-6-16-30-27-22(28)17-24(18-23(27)29)9-3-4-10-24/h5,7-8H,3-4,6,9-18H2,1-2H3 OVGOHHDHXOMVSA-UHFFFAOYSA-N 50007506 8-{3-[4-(2,3-Dimethyl-phenyl)-piperazin-1-yl]-propoxy}-8-aza-spiro[4.5]decane-7,9-dione(HCl0.5H2O)::CHEMBL418526 D(2) dopamine receptor Rattus norvegicus 2000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007506&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280586 103920781 CHEMBL418526 ZINC13820848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757545 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757548 O=C1CC2(CCCC2)CC(=O)N1OCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H30N4O3S/c28-20-16-23(8-3-4-9-23)17-21(29)27(20)30-15-5-10-25-11-13-26(14-12-25)22-18-6-1-2-7-19(18)31-24-22/h1-2,6-7H,3-5,8-17H2 RJSZSZMMKYSISN-UHFFFAOYSA-N 50007481 8-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-propoxy]-8-aza-spiro[4.5]decane-7,9-dione(HCl0.5H2O)::CHEMBL276175 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007481&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3081681 103920756 CHEMBL276175 ZINC01542241 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757549 Cc1ccccc1N1CCN(CCCON2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C22H25N3O3/c1-17-7-2-5-10-20(17)24-14-12-23(13-15-24)11-6-16-28-25-21(26)18-8-3-4-9-19(18)22(25)27/h2-5,7-10H,6,11-16H2,1H3 UNIFXVXVSGKAEI-UHFFFAOYSA-N 50007500 2-[3-(4-o-Tolyl-piperazin-1-yl)-propoxy]-isoindole-1,3-dione::CHEMBL10692 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007500&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3029002 103920775 CHEMBL10692 ZINC13820884 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757551 COc1ccccc1N1CCN(CCON2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C22H31N3O4/c1-28-19-7-3-2-6-18(19)24-12-10-23(11-13-24)14-15-29-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3 OFDPQLQCHAJCNC-UHFFFAOYSA-N 50007486 8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethoxy}-8-aza-spiro[4.5]decane-7,9-dione(2.0HCl)::CHEMBL276378 D(2) dopamine receptor Rattus norvegicus 740 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007486&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4742678 103920761 CHEMBL276378 ZINC53070565 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757554 COc1ccccc1N1CCN(CCCON2C(=O)c3ccccc3C2=O)CC1 InChI=1S/C22H25N3O4/c1-28-20-10-5-4-9-19(20)24-14-12-23(13-15-24)11-6-16-29-25-21(26)17-7-2-3-8-18(17)22(25)27/h2-5,7-10H,6,11-16H2,1H3 JOGMHYGTFXDXCG-UHFFFAOYSA-N 50007502 2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-isoindole-1,3-dione::CHEMBL10907 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm00107a028 10.7270/Q2D21Z6P 1672156 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007502&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14280597 103920777 CHEMBL10907 ZINC13820878 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50737097 C(NCc1ccccc1)[C@H]1CCc2ccc3[nH]ccc3c2O1 InChI=1S/C19H20N2O/c1-2-4-14(5-3-1)12-20-13-16-8-6-15-7-9-18-17(10-11-21-18)19(15)22-16/h1-5,7,9-11,16,20-21H,6,8,12-13H2/t16-/m1/s1 AERWLNZHDGJKMO-MRXNPFEDSA-N 50077569 Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]indol-2-yl)methyl]-amine::CHEMBL60185 D(2) dopamine receptor Rattus norvegicus 1.9 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10613605 103970338 CHEMBL60185 ZINC12356074 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50737098 O=c1[nH]c2ccc3CC[C@H](CNCc4ccccc4)Oc3c2[nH]1 InChI=1S/C18H19N3O2/c22-18-20-15-9-7-13-6-8-14(23-17(13)16(15)21-18)11-19-10-12-4-2-1-3-5-12/h1-5,7,9,14,19H,6,8,10-11H2,(H2,20,21,22)/t14-/m1/s1 NJDDOYGAHXQMEQ-CQSZACIVSA-N 50109021 (R)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one::CHEMBL420986 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109021&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9861459 104004062 CHEMBL420986 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50737103 O=C1Cc2c(N1)ccc1CC[C@H](CNCc3ccccc3)Oc21 InChI=1S/C19H20N2O2/c22-18-10-16-17(21-18)9-7-14-6-8-15(23-19(14)16)12-20-11-13-4-2-1-3-5-13/h1-5,7,9,15,20H,6,8,10-12H2,(H,21,22)/t15-/m1/s1 NPATVCXCHCPFCB-OAHLLOKOSA-N 50077581 (R)-2-(Benzylamino-methyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indol-8-one::CHEMBL303556 D(2) dopamine receptor Rattus norvegicus 5.9 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10063875 103970350 CHEMBL303556 ZINC13586902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50737108 FC(F)(F)c1nc2ccc3CCC(CNCc4ccccc4)Oc3c2[nH]1 InChI=1S/C19H18F3N3O/c20-19(21,22)18-24-15-9-7-13-6-8-14(26-17(13)16(15)25-18)11-23-10-12-4-2-1-3-5-12/h1-5,7,9,14,23H,6,8,10-11H2,(H,24,25) JFFIIIVILGKQSZ-UHFFFAOYSA-N 50109019 Benzyl-(2-trifluoromethyl-3,6,7,8-tetrahydro-chromeno[7,8-d]imidazol-8-ylmethyl)-amine::CHEMBL313851 D(2) dopamine receptor Rattus norvegicus 5.8 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9820313 104004060 CHEMBL313851 ZINC13586899 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50737112 O=c1[nH]c2ccc3CC[C@@H](CNCc4ccccc4)Oc3c2[nH]1 InChI=1S/C18H19N3O2/c22-18-20-15-9-7-13-6-8-14(23-17(13)16(15)21-18)11-19-10-12-4-2-1-3-5-12/h1-5,7,9,14,19H,6,8,10-11H2,(H2,20,21,22)/t14-/m0/s1 NJDDOYGAHXQMEQ-AWEZNQCLSA-N 50109024 (S)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one::CHEMBL93753 D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10470579 104004065 CHEMBL93753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50737113 O=c1[nH]c2ccc3CCC(CNCc4ccccc4)Oc3c2[nH]1 InChI=1S/C18H19N3O2/c22-18-20-15-9-7-13-6-8-14(23-17(13)16(15)21-18)11-19-10-12-4-2-1-3-5-12/h1-5,7,9,14,19H,6,8,10-11H2,(H2,20,21,22) NJDDOYGAHXQMEQ-UHFFFAOYSA-N 50109020 8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one::CHEMBL93779 D(2) dopamine receptor Rattus norvegicus 0.140000 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948584 104004061 CHEMBL93779 ZINC13586901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751652 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC1CCCC1=O InChI=1S/C18H26ClN3O3/c1-3-22(4-2)9-8-21-18(24)12-10-13(19)14(20)11-17(12)25-16-7-5-6-15(16)23/h10-11,16H,3-9,20H2,1-2H3,(H,21,24) PWIMALGNBNRQPH-UHFFFAOYSA-N 50023815 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo-cyclopentyloxy)-benzamide::CHEMBL39328 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116892 103934115 CHEMBL39328 ZINC29327816 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751653 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC1CCCC[C@H]1OC InChI=1S/C20H32ClN3O3/c1-4-24(5-2)11-10-23-20(25)14-12-15(21)16(22)13-19(14)27-18-9-7-6-8-17(18)26-3/h12-13,17-18H,4-11,22H2,1-3H3,(H,23,25)/t17-,18?/m1/s1 KUVDELQPGAIHCS-QNSVNVJESA-N 50023809 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-methoxy-cyclohexyloxy)-benzamide::CHEMBL291051 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286391 103934109 CHEMBL291051 ZINC29339251 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751654 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(C)(C)O InChI=1S/C17H28ClN3O3/c1-5-21(6-2)8-7-20-16(22)12-9-13(18)14(19)10-15(12)24-11-17(3,4)23/h9-10,23H,5-8,11,19H2,1-4H3,(H,20,22) MRBUKSRULDIERT-UHFFFAOYSA-N 50023810 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-2-methyl-propoxy)-benzamide::CHEMBL41595 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116935 103934110 CHEMBL41595 ZINC29339575 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751655 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC(CC=C)C(C)=O InChI=1S/C19H28ClN3O3/c1-5-8-17(13(4)24)26-18-12-16(21)15(20)11-14(18)19(25)22-9-10-23(6-2)7-3/h5,11-12,17H,1,6-10,21H2,2-4H3,(H,22,25) OXAYWGRIUZPWTG-UHFFFAOYSA-N 50023816 2-(1-Acetyl-but-3-enyloxy)-4-amino-5-chloro-N-(2-diethylamino-ethyl)-benzamide::CHEMBL289547 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116900 103934116 CHEMBL289547 ZINC29340754 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751656 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(=O)C(C)C InChI=1S/C18H28ClN3O3/c1-5-22(6-2)8-7-21-18(24)13-9-14(19)15(20)10-17(13)25-11-16(23)12(3)4/h9-10,12H,5-8,11,20H2,1-4H3,(H,21,24) MSCZCXPVLRFFCL-UHFFFAOYSA-N 50023817 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(3-methyl-2-oxo-butoxy)-benzamide::CHEMBL39442 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116895 103934117 CHEMBL39442 ZINC29323451 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751657 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC1=NCCN1 InChI=1S/C17H26ClN5O2/c1-3-23(4-2)8-7-22-17(24)12-9-13(18)14(19)10-15(12)25-11-16-20-5-6-21-16/h9-10H,3-8,11,19H2,1-2H3,(H,20,21)(H,22,24) XFQDPLHGGFSXQR-UHFFFAOYSA-N 50023818 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(4,5-dihydro-1H-imidazol-2-ylmethoxy)-benzamide::CHEMBL416235 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116929 103934118 CHEMBL416235 ZINC29336368 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751659 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCC(C)O InChI=1S/C17H28ClN3O3/c1-4-21(5-2)8-7-20-17(23)13-10-14(18)15(19)11-16(13)24-9-6-12(3)22/h10-12,22H,4-9,19H2,1-3H3,(H,20,23) GCTXIRBZSHJNFY-UHFFFAOYSA-N 50023820 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(3-hydroxy-butoxy)-benzamide::CHEMBL289864 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023820&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116936 103934120 CHEMBL289864 ZINC29339574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751660 CCN(CC)CCNC(=O)c1cc(Cl)c(N)c2c(C)c(C)oc12 InChI=1S/C17H24ClN3O2/c1-5-21(6-2)8-7-20-17(22)12-9-13(18)15(19)14-10(3)11(4)23-16(12)14/h9H,5-8,19H2,1-4H3,(H,20,22) ZRVXWCHHUAXJDI-UHFFFAOYSA-N 50023821 4-Amino-5-chloro-2,3-dimethyl-benzofuran-7-carboxylic acid (2-diethylamino-ethyl)-amide::CHEMBL39356 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023821&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116959 103934121 CHEMBL39356 ZINC29324057 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751661 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCOCCOC InChI=1S/C17H28ClN3O4/c1-4-21(5-2)7-6-20-17(22)13-10-14(18)15(19)11-16(13)25-12-24-9-8-23-3/h10-11H,4-9,12,19H2,1-3H3,(H,20,22) ZVPMWLYIHMIYJK-UHFFFAOYSA-N 50023823 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-methoxy-ethoxymethoxy)-benzamide::CHEMBL39689 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116940 103934123 CHEMBL39689 ZINC29331354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751662 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 5.2 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751663 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC\C(C)=N\OC InChI=1S/C17H27ClN4O3/c1-5-22(6-2)8-7-20-17(23)13-9-14(18)15(19)10-16(13)25-11-12(3)21-24-4/h9-10H,5-8,11,19H2,1-4H3,(H,20,23)/b21-12+ GHRFSBVRHNZRAR-CIAFOILYSA-N 50023822 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-methoxyimino-propoxy)-benzamide::CHEMBL39046 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116905 103934122 CHEMBL39046 ZINC29334298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751664 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(C)N=O InChI=1S/C16H25ClN4O3/c1-4-21(5-2)7-6-19-16(22)12-8-13(17)14(18)9-15(12)24-10-11(3)20-23/h8-9,11H,4-7,10,18H2,1-3H3,(H,19,22) XLNXVJZECOAZJD-UHFFFAOYSA-N 50023826 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxyimino-propoxy)-benzamide::CHEMBL39201 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023826&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54475895 103934125 CHEMBL39201 ZINC29337971 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751665 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC\C=C\C InChI=1S/C17H26ClN3O2/c1-4-7-10-23-16-12-15(19)14(18)11-13(16)17(22)20-8-9-21(5-2)6-3/h4,7,11-12H,5-6,8-10,19H2,1-3H3,(H,20,22)/b7-4+ ZNXVUSMMHQHHSH-QPJJXVBHSA-N 50023827 4-Amino-2-but-2-enyloxy-5-chloro-N-(2-diethylamino-ethyl)-benzamide::CHEMBL38963 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023827&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116883 103934126 CHEMBL38963 ZINC29336485 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751666 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC1CO1 InChI=1S/C16H24ClN3O3/c1-3-20(4-2)6-5-19-16(21)12-7-13(17)14(18)8-15(12)23-10-11-9-22-11/h7-8,11H,3-6,9-10,18H2,1-2H3,(H,19,21) UQNHXFUKDOKREV-UHFFFAOYSA-N 50023825 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-oxiranylmethoxy-benzamide::CHEMBL41265 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023825&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116924 103934124 CHEMBL41265 ZINC29341015 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751667 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC1CCCCC1=O InChI=1S/C19H28ClN3O3/c1-3-23(4-2)10-9-22-19(25)13-11-14(20)15(21)12-18(13)26-17-8-6-5-7-16(17)24/h11-12,17H,3-10,21H2,1-2H3,(H,22,25) QIIYAJZQOKYUDR-UHFFFAOYSA-N 50023828 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo-cyclohexyloxy)-benzamide::CHEMBL433052 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023828&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116891 103934127 CHEMBL433052 ZINC29333207 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751668 CCCOc1cc(N)c(Cl)cc1C(=O)NCCN(CC)CC InChI=1S/C16H26ClN3O2/c1-4-9-22-15-11-14(18)13(17)10-12(15)16(21)19-7-8-20(5-2)6-3/h10-11H,4-9,18H2,1-3H3,(H,19,21) CSJPRGDPEWTNSB-UHFFFAOYSA-N 50023829 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-propoxy-benzamide::CHEMBL40672 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023829&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116885 103934128 CHEMBL40672 ZINC29323949 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751670 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(=O)c1ccccc1 InChI=1S/C21H26ClN3O3/c1-3-25(4-2)11-10-24-21(27)16-12-17(22)18(23)13-20(16)28-14-19(26)15-8-6-5-7-9-15/h5-9,12-13H,3-4,10-11,14,23H2,1-2H3,(H,24,27) UFPUUPPDXVYKPL-UHFFFAOYSA-N 50023819 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo-2-phenyl-ethoxy)-benzamide::CHEMBL41706 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116890 103934119 CHEMBL41706 ZINC29336444 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751671 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCc1ccccn1 InChI=1S/C19H25ClN4O2/c1-3-24(4-2)10-9-23-19(25)15-11-16(20)17(21)12-18(15)26-13-14-7-5-6-8-22-14/h5-8,11-12H,3-4,9-10,13,21H2,1-2H3,(H,23,25) WJXMHSPYDSGKRB-UHFFFAOYSA-N 50023832 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(pyridin-2-ylmethoxy)-benzamide::CHEMBL417148 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023832&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116928 103934131 CHEMBL417148 ZINC29322449 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751672 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC1CCCO1 InChI=1S/C18H28ClN3O3/c1-3-22(4-2)8-7-21-18(23)14-10-15(19)16(20)11-17(14)25-12-13-6-5-9-24-13/h10-11,13H,3-9,12,20H2,1-2H3,(H,21,23) NZOKUUUJIFFZKA-UHFFFAOYSA-N 50023830 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(tetrahydro-furan-2-ylmethoxy)-benzamide;hydrochloride::CHEMBL36618 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023830&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116925 103934129 CHEMBL36618 ZINC29322480 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751673 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC(C)C(C)N=O InChI=1S/C17H27ClN4O3/c1-5-22(6-2)8-7-20-17(23)13-9-14(18)15(19)10-16(13)25-12(4)11(3)21-24/h9-12H,5-8,19H2,1-4H3,(H,20,23) NDPJNYXVIMENNG-UHFFFAOYSA-N 50023833 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxyimino-1-methyl-propoxy)-benzamide::CHEMBL41885 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023833&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54105703 103934132 CHEMBL41885 ZINC29339143 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751674 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC(C)C(C)=O InChI=1S/C17H26ClN3O3/c1-5-21(6-2)8-7-20-17(23)13-9-14(18)15(19)10-16(13)24-12(4)11(3)22/h9-10,12H,5-8,19H2,1-4H3,(H,20,23) ZYOJXUNLLOBURP-UHFFFAOYSA-N 50023831 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(1-methyl-2-oxo-propoxy)-benzamide::CHEMBL38594 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023831&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 59692 103934130 CHEMBL38594 ZINC01851921 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751675 Oc1cc2nn[nH]c2cc1C(=O)NCC1CCCN1CC=C InChI=1S/C15H19N5O2/c1-2-5-20-6-3-4-10(20)9-16-15(22)11-7-12-13(8-14(11)21)18-19-17-12/h2,7-8,10,21H,1,3-6,9H2,(H,16,22)(H,17,18,19) BSLSUCCQZXRXBT-UHFFFAOYSA-N 50023836 6-Hydroxy-1H-benzotriazole-5-carboxylic acid (1-allyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL39741 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023836&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116957 103934135 CHEMBL39741 ZINC29323634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751676 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(C)O InChI=1S/C16H26ClN3O3/c1-4-20(5-2)7-6-19-16(22)12-8-13(17)14(18)9-15(12)23-10-11(3)21/h8-9,11,21H,4-7,10,18H2,1-3H3,(H,19,22) GATCOSFCYSJURA-UHFFFAOYSA-N 50023813 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-propoxy)-benzamide::CHEMBL290069::R-4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-propoxy)-benzamide::S-4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-propoxy)-benzamide D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116908 103934113 CHEMBL290069 ZINC29341264 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751677 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC1OCCO1 InChI=1S/C17H26ClN3O4/c1-3-21(4-2)6-5-20-17(22)12-9-13(18)14(19)10-15(12)25-11-16-23-7-8-24-16/h9-10,16H,3-8,11,19H2,1-2H3,(H,20,22) QYYQYTDIYJRROU-UHFFFAOYSA-N 50023835 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-([1,3]dioxolan-2-ylmethoxy)-benzamide::CHEMBL289229 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116923 103934134 CHEMBL289229 ZINC29335782 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751678 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(C)=C InChI=1S/C17H26ClN3O2/c1-5-21(6-2)8-7-20-17(22)13-9-14(18)15(19)10-16(13)23-11-12(3)4/h9-10H,3,5-8,11,19H2,1-2,4H3,(H,20,22) ZOZQCFAQPINHQK-UHFFFAOYSA-N 50023837 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-methyl-allyloxy)-benzamide::CHEMBL289415 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023837&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116882 103934136 CHEMBL289415 ZINC29336084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751679 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC1COC(C)(C)O1 InChI=1S/C19H30ClN3O4/c1-5-23(6-2)8-7-22-18(24)14-9-15(20)16(21)10-17(14)25-11-13-12-26-19(3,4)27-13/h9-10,13H,5-8,11-12,21H2,1-4H3,(H,22,24) WGRGESBZCGZKAN-UHFFFAOYSA-N 50023834 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-benzamide::CHEMBL43567 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023834&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116920 103934133 CHEMBL43567 ZINC29338437 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751680 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(O)COC InChI=1S/C17H28ClN3O4/c1-4-21(5-2)7-6-20-17(23)13-8-14(18)15(19)9-16(13)25-11-12(22)10-24-3/h8-9,12,22H,4-7,10-11,19H2,1-3H3,(H,20,23) YUTQXXYJQOQDDA-UHFFFAOYSA-N 50023842 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-3-methoxy-propoxy)-benzamide::CHEMBL38443 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023842&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116931 103934141 CHEMBL38443 ZINC29333217 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751681 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(O)Cc1ccccc1 InChI=1S/C22H30ClN3O3/c1-3-26(4-2)11-10-25-22(28)18-13-19(23)20(24)14-21(18)29-15-17(27)12-16-8-6-5-7-9-16/h5-9,13-14,17,27H,3-4,10-12,15,24H2,1-2H3,(H,25,28) IYRYTQPCNJFYCL-UHFFFAOYSA-N 50023839 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-3-phenyl-propoxy)-benzamide::CHEMBL39669 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116919 103934138 CHEMBL39669 ZINC29326982 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751682 CCN1CCCNC(=O)c2cc(Cl)c(N)cc2OCCOCC1 InChI=1S/C16H24ClN3O3/c1-2-20-5-3-4-19-16(21)12-10-13(17)14(18)11-15(12)23-9-8-22-7-6-20/h10-11H,2-9,18H2,1H3,(H,19,21) XVYMPLWZBYVRPM-UHFFFAOYSA-N 50023840 3-Amino-2-chloro-11-ethyl-6,7,10,11,12,13,14,15-octahydro-9H-5,8-dioxa-11,15-diaza-benzocyclotetradecen-16-one::CHEMBL41530 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023840&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286504 103934139 CHEMBL41530 ZINC29340135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751684 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC1CCCC[C@@H]1O InChI=1S/C19H30ClN3O3/c1-3-23(4-2)10-9-22-19(25)13-11-14(20)15(21)12-18(13)26-17-8-6-5-7-16(17)24/h11-12,16-17,24H,3-10,21H2,1-2H3,(H,22,25)/t16-,17?/m0/s1 KJZIHOYWZYDQEJ-BHWOMJMDSA-N 50023841 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-cyclohexyloxy)-benzamide::CHEMBL288112 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023841&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286792 103934140 CHEMBL288112 ZINC29326033 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751685 CCCC(=O)COc1cc(N)c(Cl)cc1C(=O)NCCN(CC)CC InChI=1S/C18H28ClN3O3/c1-4-7-13(23)12-25-17-11-16(20)15(19)10-14(17)18(24)21-8-9-22(5-2)6-3/h10-11H,4-9,12,20H2,1-3H3,(H,21,24) FTMLVIOQPVOHIU-UHFFFAOYSA-N 50023838 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo-pentyloxy)-benzamide::CHEMBL41969 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023838&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116898 103934137 CHEMBL41969 ZINC29339194 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751686 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC(C)C(=O)CC InChI=1S/C18H28ClN3O3/c1-5-16(23)12(4)25-17-11-15(20)14(19)10-13(17)18(24)21-8-9-22(6-2)7-3/h10-12H,5-9,20H2,1-4H3,(H,21,24) SCZOBUCEGRITKJ-UHFFFAOYSA-N 50023846 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(1-methyl-2-oxo-butoxy)-benzamide::CHEMBL39173 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023846&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116902 103934145 CHEMBL39173 ZINC29336379 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751687 CCC(Oc1cc(N)c(Cl)cc1C(=O)NCCN(CC)CC)C(C)=O InChI=1S/C18H28ClN3O3/c1-5-16(12(4)23)25-17-11-15(20)14(19)10-13(17)18(24)21-8-9-22(6-2)7-3/h10-11,16H,5-9,20H2,1-4H3,(H,21,24) STINTIGQRLYQGY-UHFFFAOYSA-N 50023847 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(1-ethyl-2-oxo-propoxy)-benzamide::CHEMBL39930 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116894 103934146 CHEMBL39930 ZINC29325364 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751688 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCOC InChI=1S/C16H26ClN3O3/c1-4-20(5-2)7-6-19-16(21)12-10-13(17)14(18)11-15(12)23-9-8-22-3/h10-11H,4-9,18H2,1-3H3,(H,19,21) OMSUUTLTLCFHGV-UHFFFAOYSA-N 50023845 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-methoxy-ethoxy)-benzamide::CHEMBL41369 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116937 103934144 CHEMBL41369 ZINC29339206 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751689 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(C)OC InChI=1S/C17H28ClN3O3/c1-5-21(6-2)8-7-20-17(22)13-9-14(18)15(19)10-16(13)24-11-12(3)23-4/h9-10,12H,5-8,11,19H2,1-4H3,(H,20,22) NRFWWEJRUBOFAK-UHFFFAOYSA-N 50023849 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-methoxy-propoxy)-benzamide::CHEMBL289947 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023849&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116939 103934148 CHEMBL289947 ZINC29337737 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751690 CCN(CC)CCN1CCOc2cc(N)c(Cl)cc2C1=O InChI=1S/C15H22ClN3O2/c1-3-18(4-2)5-6-19-7-8-21-14-10-13(17)12(16)9-11(14)15(19)20/h9-10H,3-8,17H2,1-2H3 IDDVJDBMBMGEBI-UHFFFAOYSA-N 50023843 8-Amino-7-chloro-4-(2-diethylamino-ethyl)-3,4-dihydro-2H-benzo[f][1,4]oxazepin-5-one::CHEMBL41832 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116962 103934142 CHEMBL41832 ZINC29340725 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751691 CCN(CC)CCN(C)C(=O)c1cc(Cl)c(N)cc1O InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17(3)14(20)10-8-11(15)12(16)9-13(10)19/h8-9,19H,4-7,16H2,1-3H3 QBAICVWPQKDBRR-UHFFFAOYSA-N 50023848 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-hydroxy-N-methyl-benzamide; hydrochloride::CHEMBL541796 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116947 103934147 CHEMBL541796 ZINC29321971 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751692 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC1(C)CO1 InChI=1S/C17H26ClN3O3/c1-4-21(5-2)7-6-20-16(22)12-8-13(18)14(19)9-15(12)23-10-17(3)11-24-17/h8-9H,4-7,10-11,19H2,1-3H3,(H,20,22) TWSQEZGWEOFJBS-UHFFFAOYSA-N 50023844 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-methyl-oxiranylmethoxy)-benzamide::CHEMBL41353 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116921 103934143 CHEMBL41353 ZINC29341008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751693 CC(Oc1cc2nn[nH]c2cc1C(=O)NCC1CCCN1CC=C)C(C)=O InChI=1S/C19H25N5O3/c1-4-7-24-8-5-6-14(24)11-20-19(26)15-9-16-17(22-23-21-16)10-18(15)27-13(3)12(2)25/h4,9-10,13-14H,1,5-8,11H2,2-3H3,(H,20,26)(H,21,22,23) BAXUVFHDSHJTER-UHFFFAOYSA-N 50023854 6-(1-Methyl-2-oxo-propoxy)-1H-benzotriazole-5-carboxylic acid (1-allyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL290998 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116958 103934153 CHEMBL290998 ZINC29323626 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751694 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC(C)(C)C(C)=O InChI=1S/C18H28ClN3O3/c1-6-22(7-2)9-8-21-17(24)13-10-14(19)15(20)11-16(13)25-18(4,5)12(3)23/h10-11H,6-9,20H2,1-5H3,(H,21,24) QRUGIBFAVQDPIS-UHFFFAOYSA-N 50023855 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(1,1-dimethyl-2-oxo-propoxy)-benzamide::CHEMBL290303 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116969 103934154 CHEMBL290303 ZINC29326624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751695 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC1CCCC[C@@H]1OC InChI=1S/C20H32ClN3O3/c1-4-24(5-2)11-10-23-20(25)14-12-15(21)16(22)13-19(14)27-18-9-7-6-8-17(18)26-3/h12-13,17-18H,4-11,22H2,1-3H3,(H,23,25)/t17-,18?/m0/s1 KUVDELQPGAIHCS-ZENAZSQFSA-N 50023852 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-methoxy-cyclohexyloxy)-benzamide::CHEMBL290661 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44286312 103934151 CHEMBL290661 ZINC29331362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751696 CCN(CC)CCN1C(C)=C(C)Oc2cc(NC=O)c(Cl)cc2C1=O InChI=1S/C18H24ClN3O3/c1-5-21(6-2)7-8-22-12(3)13(4)25-17-10-16(20-11-23)15(19)9-14(17)18(22)24/h9-11H,5-8H2,1-4H3,(H,20,23) UVSZNGCSQZOGAF-UHFFFAOYSA-N 50023859 CHEMBL289070::N-[7-Chloro-4-(2-diethylamino-ethyl)-2,3-dimethyl-5-oxo-4,5-dihydro-benzo[f][1,4]oxazepin-8-yl]-formamide D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116960 103934158 CHEMBL289070 C06049 ZINC29326066 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751697 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC(C)C#N InChI=1S/C16H23ClN4O2/c1-4-21(5-2)7-6-20-16(22)12-8-13(17)14(19)9-15(12)23-11(3)10-18/h8-9,11H,4-7,19H2,1-3H3,(H,20,22) BTPGDRXWEDAPAP-UHFFFAOYSA-N 50023853 4-Amino-5-chloro-2-(cyano-methyl-methoxy)-N-(2-diethylamino-ethyl)-benzamide::CHEMBL43351 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116887 103934152 CHEMBL43351 ZINC29341102 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751698 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(=O)CC InChI=1S/C17H26ClN3O3/c1-4-12(22)11-24-16-10-15(19)14(18)9-13(16)17(23)20-7-8-21(5-2)6-3/h9-10H,4-8,11,19H2,1-3H3,(H,20,23) DDCPQGNTWWVLGM-UHFFFAOYSA-N 50023858 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo-butoxy)-benzamide::CHEMBL42978 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116893 103934157 CHEMBL42978 ZINC29339604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751699 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(O)CO InChI=1S/C16H26ClN3O4/c1-3-20(4-2)6-5-19-16(23)12-7-13(17)14(18)8-15(12)24-10-11(22)9-21/h7-8,11,21-22H,3-6,9-10,18H2,1-2H3,(H,19,23) NGDAQDUJJTXLSR-UHFFFAOYSA-N 50023850 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2,3-dihydroxy-propoxy)-benzamide::CHEMBL38982 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023850&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116930 103934149 CHEMBL38982 ZINC29333226 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751700 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(OC)OC InChI=1S/C17H28ClN3O4/c1-5-21(6-2)8-7-20-17(22)12-9-13(18)14(19)10-15(12)25-11-16(23-3)24-4/h9-10,16H,5-8,11,19H2,1-4H3,(H,20,22) XWXSUOFPQBJJNG-UHFFFAOYSA-N 50023851 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2,2-dimethoxy-ethoxy)-benzamide::CHEMBL41211 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116938 103934150 CHEMBL41211 ZINC29340790 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751701 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(=O)OC InChI=1S/C16H24ClN3O4/c1-4-20(5-2)7-6-19-16(22)11-8-12(17)13(18)9-14(11)24-10-15(21)23-3/h8-9H,4-7,10,18H2,1-3H3,(H,19,22) TYZOHBMALJGRIB-UHFFFAOYSA-N 50023862 CHEMBL416980::[5-Amino-4-chloro-2-(2-diethylamino-ethylcarbamoyl)-phenoxy]-acetic acid methyl ester D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116888 103934161 CHEMBL416980 ZINC29341090 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751702 CCN(CC)CCN1C(C)=C(C)Oc2cc(N)c(Cl)cc2C1=O InChI=1S/C17H24ClN3O2/c1-5-20(6-2)7-8-21-11(3)12(4)23-16-10-15(19)14(18)9-13(16)17(21)22/h9-10H,5-8,19H2,1-4H3 NGKKXOWMANWJNE-UHFFFAOYSA-N 50023863 8-Amino-7-chloro-4-(2-diethylamino-ethyl)-2,3-dimethyl-4H-benzo[f][1,4]oxazepin-5-one::CHEMBL41833 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116961 103934162 CHEMBL41833 ZINC29340728 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751703 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC=C InChI=1S/C16H24ClN3O2/c1-4-9-22-15-11-14(18)13(17)10-12(15)16(21)19-7-8-20(5-2)6-3/h4,10-11H,1,5-9,18H2,2-3H3,(H,19,21) XTDYXEMQYOEXKI-UHFFFAOYSA-N 50023864 2-Allyloxy-4-amino-5-chloro-N-(2-diethylamino-ethyl)-benzamide::CHEMBL290499 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116880 103934163 CHEMBL290499 ZINC29330106 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753388 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 3500 ChEMBL 10.1021/jm00128a044 10.7270/Q237799C 2569041 Cannon, JG; Jackson, H; Long, JP; Leonard, P; Bhatnagar, RK College of Pharmacy University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753390 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.045000 ChEMBL 10.1021/jm00128a044 10.7270/Q237799C 2569041 Cannon, JG; Jackson, H; Long, JP; Leonard, P; Bhatnagar, RK College of Pharmacy University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753392 CCCN1CCc2cccc-3c2[C@H]1Cc1c(OC)ccc(OC)c-31 InChI=1S/C21H25NO2/c1-4-11-22-12-10-14-6-5-7-15-20(14)17(22)13-16-18(23-2)8-9-19(24-3)21(15)16/h5-9,17H,4,10-13H2,1-3H3/t17-/m1/s1 VOWGXLROCIXGGB-QGZVFWFLSA-N 50017513 8,11-Dimethoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL61377 D(2) dopamine receptor Rattus norvegicus 770 ChEMBL 10.1021/jm00128a044 10.7270/Q237799C 2569041 Cannon, JG; Jackson, H; Long, JP; Leonard, P; Bhatnagar, RK College of Pharmacy University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14539653 103928781 CHEMBL61377 ZINC26143451 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753394 COc1ccc(OC)c-2c1C[C@H]1N(C)CCc3cccc-2c13 InChI=1S/C19H21NO2/c1-20-10-9-12-5-4-6-13-18(12)15(20)11-14-16(21-2)7-8-17(22-3)19(13)14/h4-8,15H,9-11H2,1-3H3/t15-/m1/s1 DYMYTLRHYCZMTM-OAHLLOKOSA-N 50017514 8,11-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL300329 D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm00128a044 10.7270/Q237799C 2569041 Cannon, JG; Jackson, H; Long, JP; Leonard, P; Bhatnagar, RK College of Pharmacy University of Iowa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14539640 103928782 CHEMBL300329 ZINC29569032 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753396 CN([C@H]1CCCC[C@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18+/m0/s1 VQLPLYSROCPWFF-ZWKOTPCHSA-N 50017214 (-)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide::(SR)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide(U 50488)::CHEMBL60547 D(2) dopamine receptor Rattus norvegicus 3726 ChEMBL 10.1021/jm00128a050 10.7270/Q2ZG6STP 2547074 de Costa, BR; Bowen, WD; Hellewell, SB; George, C; Rothman, RB; Reid, AA; Walker, JM; Jacobson, AE; Rice, KC National Institute of Digestive http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017214&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9847317 103928482 CHEMBL60547 C11796 ZINC00643030 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753409 CN([C@@H]1CCCC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 InChI=1S/C19H26Cl2N2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23/h8-9,12,17-18H,2-7,10-11,13H2,1H3/t17-,18+/m1/s1 VQLPLYSROCPWFF-MSOLQXFVSA-N 50008848 (+)2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide::(RS)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide(U 50488)::2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1-yl-cyclohexyl)-acetamide::CHEMBL301867 D(2) dopamine receptor Rattus norvegicus 14039 ChEMBL 10.1021/jm00128a050 10.7270/Q2ZG6STP 2547074 de Costa, BR; Bowen, WD; Hellewell, SB; George, C; Rothman, RB; Reid, AA; Walker, JM; Jacobson, AE; Rice, KC National Institute of Digestive http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11957597 103921949 CHEMBL301867 C11796 ZINC00643035 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755330 Oc1cc2CC[C@H]3NCc4ccccc4[C@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17+/m1/s1 BGOQGUHWXBGXJW-PBHICJAKSA-N 50010685 (+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine::(6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL43345::Dihydrexidine, DHX D(2) dopamine receptor Rattus norvegicus >5000 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010685&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14708665 103923431 CHEMBL43345 ZINC26746099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755337 CCCN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 InChI=1S/C20H23NO2/c1-2-9-21-12-14-5-3-4-6-15(14)20-16-11-19(23)18(22)10-13(16)7-8-17(20)21/h3-6,10-11,17,20,22-23H,2,7-9,12H2,1H3/t17-,20-/m1/s1 VNVHTKVGILYCGH-YLJYHZDGSA-N 50010684 (6aR,12bS)-6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::6-Propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL299161::N-n-propyldihydrexidine, N-Pr-DHX D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9904738 103923430 CHEMBL299161 ZINC13478187 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755338 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755343 Oc1ccc(cc1O)[C@@H]1CNCc2sccc12 InChI=1S/C13H13NO2S/c15-11-2-1-8(5-12(11)16)10-6-14-7-13-9(10)3-4-17-13/h1-5,10,14-16H,6-7H2/t10-/m0/s1 QDKUSZZMIFQVPN-JTQLQIEISA-N 50010689 (S)-4-(4,5,6,7-Tetrahydro-thieno[2,3-c]pyridin-4-yl)-benzene-1,2-diol::4-(4,5,6,7-Tetrahydro-thieno[2,3-c]pyridin-4-yl)-benzene-1,2-diol::CHEMBL407489::SK&F-89626::SK-89626 D(2) dopamine receptor Rattus norvegicus 285 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010689&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604005 103923435 CHEMBL407489 ZINC25758070 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755344 Oc1cc2CC[C@H]3NCCC[C@@H]3c2cc1O InChI=1S/C13H17NO2/c15-12-6-8-3-4-11-9(2-1-5-14-11)10(8)7-13(12)16/h6-7,9,11,14-16H,1-5H2/t9-,11-/m1/s1 IWFKJEVCXTYAFE-MWLCHTKSSA-N 50010687 1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinoline-8,9-diol::CHEMBL299430 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010687&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44294484 103923433 CHEMBL299430 ZINC29469107 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755345 Oc1cc2CCC(Cc2cc1O)NCc1ccccc1 InChI=1S/C17H19NO2/c19-16-9-13-6-7-15(8-14(13)10-17(16)20)18-11-12-4-2-1-3-5-12/h1-5,9-10,15,18-20H,6-8,11H2 YOZGWJXSKNAAGL-UHFFFAOYSA-N 50010688 6-Benzylamino-5,6,7,8-tetrahydro-naphthalene-2,3-diol::CHEMBL49634 D(2) dopamine receptor Rattus norvegicus 290 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010688&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14708673 103923434 CHEMBL49634 ZINC13604051 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755346 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755348 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 1500 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755353 CN1Cc2ccccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 InChI=1S/C18H19NO2/c1-19-10-12-4-2-3-5-13(12)18-14-9-17(21)16(20)8-11(14)6-7-15(18)19/h2-5,8-9,15,18,20-21H,6-7,10H2,1H3/t15-,18-/m1/s1 JFIXQOMKJZEWGH-CRAIPNDOSA-N 50010690 6-Methyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL51017 D(2) dopamine receptor Rattus norvegicus 136 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010690&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11543723 103923436 CHEMBL51017 ZINC29471902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755355 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus 3750 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50755356 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00168a034 10.7270/Q23X877X 1971308 Brewster, WK; Nichols, DE; Riggs, RM; Mottola, DM; Lovenberg, TW; Lewis, MH; Mailman, RB Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764267 Oc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2/t12-,14+/m0/s1 MHHLELSXRBTNRD-GXTWGEPZSA-N 50034355 (3aR,9bS)-3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::(3aR,9bS)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL285873 D(2) dopamine receptor Rattus norvegicus 49 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014056 103942556 CHEMBL285873 ZINC13826517 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748166 Fc1ccc(cc1)-n1c2CCN(CCc3ccccn3)Cc2c2cc(F)ccc12 InChI=1S/C24H21F2N3/c25-17-4-7-20(8-5-17)29-23-9-6-18(26)15-21(23)22-16-28(14-11-24(22)29)13-10-19-3-1-2-12-27-19/h1-9,12,15H,10-11,13-14,16H2 YDALBQREGQCAPU-UHFFFAOYSA-N 50367417 CHEMBL1743943 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367417 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367417&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900392 160846519 CHEMBL1743943 ZINC29480007 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748170 C(CCc1ccncc1)CN1CC(c2[nH]c3ccccc3c2C1)c1ccccc1 InChI=1S/C26H27N3/c1-2-9-21(10-3-1)23-18-29(17-7-6-8-20-13-15-27-16-14-20)19-24-22-11-4-5-12-25(22)28-26(23)24/h1-5,9-16,23,28H,6-8,17-19H2 WQEFAHPFEABWDU-UHFFFAOYSA-N 50367420 CHEMBL1743960 D(2) dopamine receptor Rattus norvegicus 404 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367420 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367420&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900379 160846522 CHEMBL1743960 ZINC29488177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748171 Clc1ccc2[nH]c3CCN(CCc4ccccn4)Cc3c2c1 InChI=1S/C18H18ClN3/c19-13-4-5-17-15(11-13)16-12-22(10-7-18(16)21-17)9-6-14-3-1-2-8-20-14/h1-5,8,11,21H,6-7,9-10,12H2 ZUMJYQHMYILRQI-UHFFFAOYSA-N 50367421 CHEMBL1743941 D(2) dopamine receptor Rattus norvegicus 103 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13772452 160846523 CHEMBL1743941 ZINC29487322 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748172 Fc1ccc2[nH]c3CCN(CCc4ccccn4)Cc3c2c1 InChI=1S/C18H18FN3/c19-13-4-5-17-15(11-13)16-12-22(10-7-18(16)21-17)9-6-14-3-1-2-8-20-14/h1-5,8,11,21H,6-7,9-10,12H2 GMBJAWMQCVGXQW-UHFFFAOYSA-N 50367422 CHEMBL1743935 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13772434 160846524 CHEMBL1743935 ZINC29487964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748173 Fc1ccc2[nH]c3CCN(CCCc4cccnc4)Cc3c2c1 InChI=1S/C19H20FN3/c20-15-5-6-18-16(11-15)17-13-23(10-7-19(17)22-18)9-2-4-14-3-1-8-21-12-14/h1,3,5-6,8,11-12,22H,2,4,7,9-10,13H2 RZXHTPCHKSYGIB-UHFFFAOYSA-N 50367423 CHEMBL1743949 D(2) dopamine receptor Rattus norvegicus 104 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367423&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60547 160846525 CHEMBL1743949 ZINC29486404 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748174 C(Cc1ccc2ccccc2n1)N1CCc2[nH]c3ccccc3c2C1 InChI=1S/C22H21N3/c1-3-7-20-16(5-1)9-10-17(23-20)11-13-25-14-12-22-19(15-25)18-6-2-4-8-21(18)24-22/h1-10,24H,11-15H2 AIQHLPHYTDDMQV-UHFFFAOYSA-N 50367424 CHEMBL1743950 D(2) dopamine receptor Rattus norvegicus 331 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367424&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13772444 160846526 CHEMBL1743950 ZINC29486936 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748176 Fc1ccc(cc1)C(CCCN1CCc2[nH]c3ccc(F)cc3c2C1)c1ccc(F)cc1 InChI=1S/C27H25F3N2/c28-20-7-3-18(4-8-20)23(19-5-9-21(29)10-6-19)2-1-14-32-15-13-27-25(17-32)24-16-22(30)11-12-26(24)31-27/h3-12,16,23,31H,1-2,13-15,17H2 FDZCICPSBGWJFW-UHFFFAOYSA-N 50367425 CHEMBL1743955 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367425 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367425&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900404 160846527 CHEMBL1743955 ZINC29486686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748177 Clc1ccc2[nH]c3CCN(CCc4ccc5ccccc5n4)Cc3c2c1 InChI=1S/C22H20ClN3/c23-16-6-8-21-18(13-16)19-14-26(12-10-22(19)25-21)11-9-17-7-5-15-3-1-2-4-20(15)24-17/h1-8,13,25H,9-12,14H2 MULKKPLNPGZBFJ-UHFFFAOYSA-N 50367426 CHEMBL1743962 D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367426&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13772454 160846528 CHEMBL1743962 ZINC29482655 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748179 Fc1ccc2[nH]c3CCN(CCCCc4ccncc4)Cc3c2c1 InChI=1S/C20H22FN3/c21-16-4-5-19-17(13-16)18-14-24(12-8-20(18)23-19)11-2-1-3-15-6-9-22-10-7-15/h4-7,9-10,13,23H,1-3,8,11-12,14H2 CFKAMVGNTODMBK-UHFFFAOYSA-N 50367427 CHEMBL1743939 D(2) dopamine receptor Rattus norvegicus 143 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367427 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367427&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13772438 160846529 CHEMBL1743939 ZINC29486965 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748180 C(CN1CC(c2[nH]c3ccccc3c2C1)c1ccccc1)Cc1cccnc1 InChI=1S/C25H25N3/c1-2-10-20(11-3-1)22-17-28(15-7-9-19-8-6-14-26-16-19)18-23-21-12-4-5-13-24(21)27-25(22)23/h1-6,8,10-14,16,22,27H,7,9,15,17-18H2 JULFDEFXVAZHOF-UHFFFAOYSA-N 50367428 CHEMBL1743953 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367428&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900377 160846530 CHEMBL1743953 ZINC29489246 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748181 Fc1ccc2[nH]c3CCN(CCc4ccc5ccccc5n4)Cc3c2c1 InChI=1S/C22H20FN3/c23-16-6-8-21-18(13-16)19-14-26(12-10-22(19)25-21)11-9-17-7-5-15-3-1-2-4-20(15)24-17/h1-8,13,25H,9-12,14H2 VYCDZWLMYZWLMJ-UHFFFAOYSA-N 50367429 CHEMBL1743942 D(2) dopamine receptor Rattus norvegicus 185 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367429&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13772442 160846531 CHEMBL1743942 ZINC29485885 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748185 Clc1ccc2[nH]c3CCN(CCCN4CCN(CC4)c4ncccn4)Cc3c2c1 InChI=1S/C22H27ClN6/c23-17-3-4-20-18(15-17)19-16-28(10-5-21(19)26-20)9-2-8-27-11-13-29(14-12-27)22-24-6-1-7-25-22/h1,3-4,6-7,15,26H,2,5,8-14,16H2 FPZOSIGPQKHIJU-UHFFFAOYSA-N 50367430 CHEMBL1743934 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367430&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900398 160846532 CHEMBL1743934 ZINC29488519 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748186 Clc1ccc2[nH]c3CCN(CCCCc4ccncc4)Cc3c2c1 InChI=1S/C20H22ClN3/c21-16-4-5-19-17(13-16)18-14-24(12-8-20(18)23-19)11-2-1-3-15-6-9-22-10-7-15/h4-7,9-10,13,23H,1-3,8,11-12,14H2 BCPUPRVRUMUHPY-UHFFFAOYSA-N 50367431 CHEMBL1743959 D(2) dopamine receptor Rattus norvegicus 106 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13772450 160846533 CHEMBL1743959 ZINC29483863 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748188 Fc1ccc(cc1)-n1c2CCN(CCCCc3ccncc3)Cc2c2cc(F)ccc12 InChI=1S/C26H25F2N3/c27-20-4-7-22(8-5-20)31-25-9-6-21(28)17-23(25)24-18-30(16-12-26(24)31)15-2-1-3-19-10-13-29-14-11-19/h4-11,13-14,17H,1-3,12,15-16,18H2 ZRJMMGIQGZDDCJ-UHFFFAOYSA-N 50367433 CHEMBL1743945 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900386 160846535 CHEMBL1743945 ZINC29487655 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748189 Fc1ccc(cc1)-n1c2CCN(CCc3cnccn3)Cc2c2cc(F)ccc12 InChI=1S/C23H20F2N4/c24-16-1-4-19(5-2-16)29-22-6-3-17(25)13-20(22)21-15-28(12-8-23(21)29)11-7-18-14-26-9-10-27-18/h1-6,9-10,13-14H,7-8,11-12,15H2 KAEOLIMAQYKEQB-UHFFFAOYSA-N 50367419 CHEMBL1743958 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367419&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900394 160846521 CHEMBL1743958 ZINC29488462 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748193 Fc1ccc2[nH]c3CCN(CCc4cnccn4)Cc3c2c1 InChI=1S/C17H17FN4/c18-12-1-2-16-14(9-12)15-11-22(8-4-17(15)21-16)7-3-13-10-19-5-6-20-13/h1-2,5-6,9-10,21H,3-4,7-8,11H2 HZSKAWJYTNOVBY-UHFFFAOYSA-N 50367434 CHEMBL1743951 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900382 160846536 CHEMBL1743951 ZINC29485476 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748194 C[C@H]1CN(CCCn2c3ccccc3c3ccccc23)C[C@@H](C)N1 InChI=1S/C21H27N3/c1-16-14-23(15-17(2)22-16)12-7-13-24-20-10-5-3-8-18(20)19-9-4-6-11-21(19)24/h3-6,8-11,16-17,22H,7,12-15H2,1-2H3/t16-,17+ GUDVQJXODNJRIJ-CALCHBBNSA-N 50019742 9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9H-carbazole::9-(3-(3,5-dimethylpiperazin-1-yl)propyl)-9H-carbazole::9-[3-((3R,5R)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-((3R,5S)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-((3S,5R)-3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole (Rimcazole) (BW234U)::9-[3-(3,5-Dimethyl-piperazin-1-yl)-propyl]-9H-carbazole(rimcazole)::CHEMBL275707::RIMCAZOLE D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019742&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53389 103930665 CHEMBL275707 ZINC22920326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748195 Clc1ccc2[nH]c3CCN(CCCc4cccnc4)Cc3c2c1 InChI=1S/C19H20ClN3/c20-15-5-6-18-16(11-15)17-13-23(10-7-19(17)22-18)9-2-4-14-3-1-8-21-12-14/h1,3,5-6,8,11-12,22H,2,4,7,9-10,13H2 QJXNUSOKENDUGP-UHFFFAOYSA-N 50367435 CHEMBL1743938 D(2) dopamine receptor Rattus norvegicus 126 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367435&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900384 160846537 CHEMBL1743938 ZINC29482955 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748196 Fc1ccc(cc1)-n1c2CCN(CCc3ccncc3)Cc2c2cc(F)ccc12 InChI=1S/C24H21F2N3/c25-18-1-4-20(5-2-18)29-23-6-3-19(26)15-21(23)22-16-28(14-10-24(22)29)13-9-17-7-11-27-12-8-17/h1-8,11-12,15H,9-10,13-14,16H2 UZGUUMLQIBTEQO-UHFFFAOYSA-N 50367432 CHEMBL1743937 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367432&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900388 160846534 CHEMBL1743937 ZINC29484235 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748198 C(CN1CCN(CC1)c1ncccn1)CN1CCc2[nH]c3ccccc3c2C1 InChI=1S/C22H28N6/c1-2-6-20-18(5-1)19-17-27(12-7-21(19)25-20)11-4-10-26-13-15-28(16-14-26)22-23-8-3-9-24-22/h1-3,5-6,8-9,25H,4,7,10-17H2 CDAZOCGTPOVALB-UHFFFAOYSA-N 50367436 CHEMBL1743947 D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900400 160846538 CHEMBL1743947 ZINC29486707 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748199 Fc1ccc(cc1)-n1c2CCN(CCCCc3ccnc4ccccc34)Cc2c2cc(F)ccc12 InChI=1S/C30H27F2N3/c31-22-8-11-24(12-9-22)35-29-13-10-23(32)19-26(29)27-20-34(18-15-30(27)35)17-4-3-5-21-14-16-33-28-7-2-1-6-25(21)28/h1-2,6-14,16,19H,3-5,15,17-18,20H2 BDVHFCSRISBQMJ-UHFFFAOYSA-N 50367437 CHEMBL1743956 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367437 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367437&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900390 160846539 CHEMBL1743956 ZINC29488445 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748200 Fc1ccc(cc1)-n1c2CCN(CCc3ccc4ccccc4n3)Cc2c2cc(F)ccc12 InChI=1S/C28H23F2N3/c29-20-6-10-23(11-7-20)33-27-12-8-21(30)17-24(27)25-18-32(16-14-28(25)33)15-13-22-9-5-19-3-1-2-4-26(19)31-22/h1-12,17H,13-16,18H2 LQISAFMWOCODSX-UHFFFAOYSA-N 50367438 CHEMBL1743957 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367438 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367438&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900396 160846540 CHEMBL1743957 ZINC29488459 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748201 Fc1ccc2[nH]c3CCN(CCc4ccncc4)Cc3c2c1 InChI=1S/C18H18FN3/c19-14-1-2-17-15(11-14)16-12-22(10-6-18(16)21-17)9-5-13-3-7-20-8-4-13/h1-4,7-8,11,21H,5-6,9-10,12H2 PMXOASNGMJAYTN-UHFFFAOYSA-N 50367418 CHEMBL1743952::Carvotroline hydrochloride D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367418 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367418&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72038 160846520 CHEMBL1743952 ZINC29485479 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748202 C(Cc1ccccn1)N1CC(c2[nH]c3ccccc3c2C1)c1ccccc1 InChI=1S/C24H23N3/c1-2-8-18(9-3-1)21-16-27(15-13-19-10-6-7-14-25-19)17-22-20-11-4-5-12-23(20)26-24(21)22/h1-12,14,21,26H,13,15-17H2 BYEGRTMNNPHEQN-UHFFFAOYSA-N 50367439 CHEMBL1743954 D(2) dopamine receptor Rattus norvegicus 600 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900375 160846541 CHEMBL1743954 ZINC29489251 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748203 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748204 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748230 C[C@@H]1CN(CCCC(=O)c2ccc(F)cc2)CCC1(O)c1ccccc1 InChI=1S/C22H26FNO2/c1-17-16-24(15-13-22(17,26)19-6-3-2-4-7-19)14-5-8-21(25)18-9-11-20(23)12-10-18/h2-4,6-7,9-12,17,26H,5,8,13-16H2,1H3/t17-,22?/m1/s1 JKXPWDUACRNDOH-PLEWWHCXSA-N 50019945 1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-methyl-4-phenyl-piperidin-1-yl)-butan-1-one::CHEMBL57140 D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299579 103930868 CHEMBL57140 ZINC29558892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748232 CCC(=O)OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccccc1 InChI=1S/C24H28FNO3/c1-2-23(28)29-24(20-7-4-3-5-8-20)14-17-26(18-15-24)16-6-9-22(27)19-10-12-21(25)13-11-19/h3-5,7-8,10-13H,2,6,9,14-18H2,1H3 HNNSFIPBXBSBPB-UHFFFAOYSA-N 50019947 CHEMBL299471::Propionic acid 1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-4-phenyl-piperidin-4-yl ester D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019947&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13869636 103930870 CHEMBL299471 ZINC29556648 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748239 CCC(=O)OC1(CCN(CCCC(=O)c2ccc(F)cc2)C[C@H]1C)c1ccccc1 InChI=1S/C25H30FNO3/c1-3-24(29)30-25(21-8-5-4-6-9-21)15-17-27(18-19(25)2)16-7-10-23(28)20-11-13-22(26)14-12-20/h4-6,8-9,11-14,19H,3,7,10,15-18H2,1-2H3/t19-,25?/m1/s1 REXOMGWVBIKJKZ-OEPVSBQMSA-N 50019946 CHEMBL56547::Propionic acid 1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-3-methyl-4-phenyl-piperidin-4-yl ester D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299566 103930869 CHEMBL56547 ZINC29559244 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748242 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccccc1 InChI=1S/C21H24FNO2/c22-19-10-8-17(9-11-19)20(24)7-4-14-23-15-12-21(25,13-16-23)18-5-2-1-3-6-18/h1-3,5-6,8-11,25H,4,7,12-16H2 FEFFZKPQSVTBAY-UHFFFAOYSA-N 50019949 1-(4-Fluoro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-butan-1-one::CHEMBL54206 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019949&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18367 103930872 CHEMBL54206 ZINC00001910 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748245 OC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C15H20FNO2/c16-13-5-3-12(4-6-13)15(19)2-1-9-17-10-7-14(18)8-11-17/h3-6,14,18H,1-2,7-11H2 OJTNFBDLVWOHKM-UHFFFAOYSA-N 50019953 1-(4-Fluoro-phenyl)-4-(4-hydroxy-piperidin-1-yl)-butan-1-one::CHEMBL59213 D(2) dopamine receptor Rattus norvegicus >5000 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019953&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 29734 103930876 CHEMBL59213 ZINC05839491 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748247 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748249 Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)c1ccccc1 InChI=1S/C21H24FNO/c22-20-10-8-19(9-11-20)21(24)7-4-14-23-15-12-18(13-16-23)17-5-2-1-3-6-17/h1-3,5-6,8-11,18H,4,7,12-16H2 GOPOBAVSYNADGN-UHFFFAOYSA-N 50019950 1-(4-Fluoro-phenyl)-4-(4-phenyl-piperidin-1-yl)-butan-1-one::CHEMBL56843 D(2) dopamine receptor Rattus norvegicus 70 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019950&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13869644 103930873 CHEMBL56843 ZINC29555346 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748254 C[C@H]1CN(CCCC(=O)c2ccc(F)cc2)CCC1(O)c1ccccc1 InChI=1S/C22H26FNO2/c1-17-16-24(15-13-22(17,26)19-6-3-2-4-7-19)14-5-8-21(25)18-9-11-20(23)12-10-18/h2-4,6-7,9-12,17,26H,5,8,13-16H2,1H3/t17-,22?/m0/s1 JKXPWDUACRNDOH-LBOXEOMUSA-N 50019954 1-(4-Fluoro-phenyl)-4-(4-hydroxy-3-methyl-4-phenyl-piperidin-1-yl)-butan-1-one::CHEMBL57029 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299467 103930877 CHEMBL57029 ZINC29557808 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748255 CCC(=O)OC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C18H24FNO3/c1-2-18(22)23-16-9-12-20(13-10-16)11-3-4-17(21)14-5-7-15(19)8-6-14/h5-8,16H,2-4,9-13H2,1H3 QFVVDDZBNJYTKR-UHFFFAOYSA-N 50019952 CHEMBL57306::Propionic acid 1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-piperidin-4-yl ester D(2) dopamine receptor Rattus norvegicus >50000 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019952&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13869646 103930875 CHEMBL57306 ZINC29560554 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748259 CCC(=O)OC1(CCN(CCCC(=O)c2ccc(F)cc2)C[C@@H]1C)c1ccccc1 InChI=1S/C25H30FNO3/c1-3-24(29)30-25(21-8-5-4-6-9-21)15-17-27(18-19(25)2)16-7-10-23(28)20-11-13-22(26)14-12-20/h4-6,8-9,11-14,19H,3,7,10,15-18H2,1-2H3/t19-,25?/m0/s1 REXOMGWVBIKJKZ-UBDBMELISA-N 50019948 CHEMBL292006::Propionic acid 1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-3-methyl-4-phenyl-piperidin-4-yl ester D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm00393a037 10.7270/Q2DB82D1 2888899 Iorio, MA; Reymer, TP; Frigeni, V Istituto Superiore di Sanit£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019948&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44299213 103930871 CHEMBL292006 ZINC05768418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751704 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC#C InChI=1S/C16H22ClN3O2/c1-4-9-22-15-11-14(18)13(17)10-12(15)16(21)19-7-8-20(5-2)6-3/h1,10-11H,5-9,18H2,2-3H3,(H,19,21) PALUTDFYUXJQGI-UHFFFAOYSA-N 50023865 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-prop-2-ynyloxy-benzamide::CHEMBL416604 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023865&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116881 103934164 CHEMBL416604 ZINC29331376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751705 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCOCCOC InChI=1S/C18H30ClN3O4/c1-4-22(5-2)7-6-21-18(23)14-12-15(19)16(20)13-17(14)26-11-10-25-9-8-24-3/h12-13H,4-11,20H2,1-3H3,(H,21,23) SBQNXJKQGLWJLB-UHFFFAOYSA-N 50023861 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-[2-(2-methoxy-ethoxy)-ethoxy]-benzamide::CHEMBL41381 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116941 103934160 CHEMBL41381 ZINC29340558 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751706 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCCC(C)OC InChI=1S/C18H30ClN3O3/c1-5-22(6-2)9-8-21-18(23)14-11-15(19)16(20)12-17(14)25-10-7-13(3)24-4/h11-13H,5-10,20H2,1-4H3,(H,21,23) MNHYAKKTEVCZLI-UHFFFAOYSA-N 50023856 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(3-methoxy-butoxy)-benzamide::CHEMBL441677 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9929376 103934155 CHEMBL441677 ZINC13885175 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751707 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCc1cc(C)no1 InChI=1S/C18H25ClN4O3/c1-4-23(5-2)7-6-21-18(24)14-9-15(19)16(20)10-17(14)25-11-13-8-12(3)22-26-13/h8-10H,4-7,11,20H2,1-3H3,(H,21,24) WBMWOBIZAUXEHQ-UHFFFAOYSA-N 50023857 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(3-methyl-isoxazol-5-ylmethoxy)-benzamide::CHEMBL41321 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116927 103934156 CHEMBL41321 ZINC29340425 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50751708 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC(C)=O InChI=1S/C16H24ClN3O3/c1-4-20(5-2)7-6-19-16(22)12-8-13(17)14(18)9-15(12)23-10-11(3)21/h8-9H,4-7,10,18H2,1-3H3,(H,19,22) MCNMUWHWVANETD-UHFFFAOYSA-N 50023860 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo-propoxy)-benzamide::CHEMBL290641 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023860&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116889 103934159 CHEMBL290641 ZINC29336448 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753540 CCN1CCC[C@H]1CNC(=O)c1cccc2CCOc12 InChI=1S/C16H22N2O2/c1-2-18-9-4-6-13(18)11-17-16(19)14-7-3-5-12-8-10-20-15(12)14/h3,5,7,13H,2,4,6,8-11H2,1H3,(H,17,19)/t13-/m0/s1 SUQDJPATQUWVDW-ZDUSSCGKSA-N 50012959 2,3-Dihydro-benzofuran-7-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL301399 D(2) dopamine receptor Rattus norvegicus 135 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14528128 103925207 CHEMBL301399 ZINC29471712 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753541 CCN1CCC[C@H]1CNC(=O)c1cc2cc(Br)ccc2cc1O InChI=1S/C18H21BrN2O2/c1-2-21-7-3-4-15(21)11-20-18(23)16-9-13-8-14(19)6-5-12(13)10-17(16)22/h5-6,8-10,15,22H,2-4,7,11H2,1H3,(H,20,23)/t15-/m0/s1 GZAZQJZLOSEEHT-HNNXBMFYSA-N 50012960 7-Bromo-3-hydroxy-naphthalene-2-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL48721 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14528118 103925208 CHEMBL48721 ZINC29469567 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753542 CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C24H28FN3O2/c1-26-18-28(21-6-3-2-4-7-21)24(23(26)30)13-16-27(17-14-24)15-5-8-22(29)19-9-11-20(25)12-10-19/h2-4,6-7,9-12H,5,8,13-18H2,1H3 QHJLPOSPWKZACG-UHFFFAOYSA-N 50004813 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one (N-methylspiperone,NMSP)::CHEMBL267932 D(2) dopamine receptor Rattus norvegicus 0.097000 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 119146 103918360 CHEMBL267932 196 ZINC02572278 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753543 CCN1CCC[C@H]1CNC(=O)c1cc2ccccc2cc1OC InChI=1S/C19H24N2O2/c1-3-21-10-6-9-16(21)13-20-19(22)17-11-14-7-4-5-8-15(14)12-18(17)23-2/h4-5,7-8,11-12,16H,3,6,9-10,13H2,1-2H3,(H,20,22)/t16-/m0/s1 ZBMMMNRPJAMYPT-INIZCTEOSA-N 50012962 3-Methoxy-naphthalene-2-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL50484 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012962&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14528115 103925210 CHEMBL50484 ZINC29465518 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753545 CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1 ZZJYIKPMDIWRSN-TZBSWOFLSA-N 50366495 (+)butaclamol::CHEMBL1255588 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37461 160845597 73298 CHEMBL1255588 ZINC01481744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753546 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.015000 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753547 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753548 CCN1CCC[C@H]1CNC(=O)c1cc2cc(I)ccc2cc1OC InChI=1S/C19H23IN2O2/c1-3-22-8-4-5-16(22)12-21-19(23)17-10-14-9-15(20)7-6-13(14)11-18(17)24-2/h6-7,9-11,16H,3-5,8,12H2,1-2H3,(H,21,23)/t16-/m0/s1 GCZXCWWIJNGSKF-INIZCTEOSA-N 50012963 7-Iodo-3-methoxy-naphthalene-2-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide (INAP)::CHEMBL301133 D(2) dopamine receptor Rattus norvegicus 168 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012963&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14528113 103925211 CHEMBL301133 ZINC29469268 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753549 CCN1CCC[C@H]1CNC(=O)c1c(I)c(ccc1OC)S(N)(=O)=O InChI=1S/C15H22IN3O4S/c1-3-19-8-4-5-10(19)9-18-15(20)13-11(23-2)6-7-12(14(13)16)24(17,21)22/h6-7,10H,3-5,8-9H2,1-2H3,(H,18,20)(H2,17,21,22)/t10-/m0/s1 HCKMONAVUWHQOT-JTQLQIEISA-N 50040082 CHEMBL307023::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-iodo-6-methoxy-3-sulfamoyl-benzamide (iodosulpride)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoyl-benzamide(iodosulpiride) D(2) dopamine receptor Rattus norvegicus 1.5 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040082&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44312731 103972143 CHEMBL307023 ZINC26376795 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753550 CCN1CCC[C@H]1CNC(=O)c1c(O)cccc1OC InChI=1S/C15H22N2O3/c1-3-17-9-5-6-11(17)10-16-15(19)14-12(18)7-4-8-13(14)20-2/h4,7-8,11,18H,3,5-6,9-10H2,1-2H3,(H,16,19)/t11-/m0/s1 MVWKVVFFVMXULU-NSHDSACASA-N 50012964 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::CHEMBL8945::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (BZM) D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10956830 103925212 CHEMBL8945 ZINC05851787 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753551 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc2CCOc12 InChI=1S/C16H21IN2O2/c1-2-19-6-3-4-13(19)10-18-16(20)14-9-12(17)8-11-5-7-21-15(11)14/h8-9,13H,2-7,10H2,1H3,(H,18,20)/t13-/m0/s1 SXAMDWYVBFWJLU-ZDUSSCGKSA-N 50012965 5-Iodo-2,3-dihydro-benzofuran-7-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide ((S)-(-)IBF)::5-Iodo-2,3-dihydro-benzofuran-7-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide (IBF)::CHEMBL48450 D(2) dopamine receptor Rattus norvegicus 0.085000 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012965&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3035942 103925213 CHEMBL48450 ZINC03784279 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753552 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.170000 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753553 CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)ccc1OC InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 CANPFCFJURGKAX-JTQLQIEISA-N 50012961 (-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide::CHEMBL267723::N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide (IBZM)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide( (S)-(-)IBZM) D(2) dopamine receptor Rattus norvegicus 0.430000 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 107995 103925209 CHEMBL267723 ZINC03786360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753554 Fc1ccc(C(=O)CCCN2CCC3(CC2)N(CNC3=O)c2ccccc2)c(I)c1 InChI=1S/C23H25FIN3O2/c24-17-8-9-19(20(25)15-17)21(29)7-4-12-27-13-10-23(11-14-27)22(30)26-16-28(23)18-5-2-1-3-6-18/h1-3,5-6,8-9,15H,4,7,10-14,16H2,(H,26,30) WNZBTQBAZJTZST-UHFFFAOYSA-N 50012966 8-[4-(4-Fluoro-2-iodo-phenyl)-4-oxo-butyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one (2-iodospiperone, 2'-ISP)::CHEMBL49405 D(2) dopamine receptor Rattus norvegicus 0.250000 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128389 103925214 CHEMBL49405 ZINC02559957 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753555 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 820 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753556 CCN1CCC[C@H]1CNC(=O)c1cc(I)ccc1OC InChI=1S/C15H21IN2O2/c1-3-18-8-4-5-12(18)10-17-15(19)13-9-11(16)6-7-14(13)20-2/h6-7,9,12H,3-5,8,10H2,1-2H3,(H,17,19)/t12-/m0/s1 JHMTYLJMPBFCTD-LBPRGKRZSA-N 50012967 CHEMBL49897::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide (iodopride)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide(iodopride) D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977544 103925215 CHEMBL49897 ZINC06385022 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753558 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 491 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753559 CC(C)NCC(O)COc1cccc2ccccc12 InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3 AQHHHDLHHXJYJD-UHFFFAOYSA-N 25761 Anapriline::Avlocardyl::CHEMBL27::PROPANOLOL(-)::PROPRANOLOL, d::PROPRANOLOL, l-::PROPRANOLOL,(+)::PROPRANOLOL,(-)::Propanolol::Propanolol,(+/-)::Propranolol::[2-hydroxy-3-(naphthalen-1-yloxy)propyl](propan-2-yl)amine D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25761&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SNP 1DY4,6EKZ,6PS5,5FUK 4946 56413049 8499 CHEMBL27 DB00571 564 C07407 ZINC00056556 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753560 COc1cc(N=[N+]=[N-])c(I)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H22IN5O2/c1-28-19-12-18(24-25-22)17(21)11-16(19)20(27)23-15-7-9-26(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13H2,1H3,(H,23,27) UFNGQEVXMTYIHB-UHFFFAOYSA-N 50012968 4-Azido-N-(1-benzyl-piperidin-4-yl)-5-iodo-2-methoxy-benzamide::4-Azido-N-(1-benzyl-piperidin-4-yl)-5-iodo-2-methoxy-benzamide (iodoazidoclebopride)::CHEMBL50154 D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012968&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3035560 103925216 CHEMBL50154 ZINC29481772 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753561 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 843 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753562 CCN1CCC[C@H]1CNC(=O)c1cc(Br)cc2CCOc12 InChI=1S/C16H21BrN2O2/c1-2-19-6-3-4-13(19)10-18-16(20)14-9-12(17)8-11-5-7-21-15(11)14/h8-9,13H,2-7,10H2,1H3,(H,18,20)/t13-/m0/s1 VRMUQJZSWAAYCB-ZDUSSCGKSA-N 50010720 5-Bromo-2,3-dihydro-benzofuran-7-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL301532 D(2) dopamine receptor Rattus norvegicus 3.9 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010720&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14528122 103923466 CHEMBL301532 ZINC29472310 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753563 NC1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2 ASXGAOFCKGHGMF-UHFFFAOYSA-N 81195 (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide::2-aminotetralin-6,7-diol;hydrobromide::6-Amino-5,6,7,8-tetrahydro-naphthalene-2,3-diol::6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::6-azanyl-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::ADTN::ADTN, (+)::CA inhibitor, 3::CHEMBL26736::MLS002172466::SMR001254097::cid_11957526::cid_3153 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3153 252657735 CHEMBL26736 ZINC03872370 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753564 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc2ccccc12 InChI=1S/C19H24N2O2/c1-3-21-12-6-8-15(21)13-20-19(22)18-16-9-5-4-7-14(16)10-11-17(18)23-2/h4-5,7,9-11,15H,3,6,8,12-13H2,1-2H3,(H,20,22)/t15-/m0/s1 ZJNZOZWOJFJDKO-HNNXBMFYSA-N 50012970 2-Methoxy-naphthalene-1-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL296978 D(2) dopamine receptor Rattus norvegicus 507 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012970&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14528120 103925218 CHEMBL296978 ZINC29470926 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757772 COc1cc(Br)c(O)c(C(=O)NC[C@H]2CCCN2Cc2ccccc2)c1OC InChI=1S/C21H25BrN2O4/c1-27-17-11-16(22)19(25)18(20(17)28-2)21(26)23-12-15-9-6-10-24(15)13-14-7-4-3-5-8-14/h3-5,7-8,11,15,25H,6,9-10,12-13H2,1-2H3,(H,23,26)/t15-/m1/s1 NCLVLZIXBDQXSP-OAHLLOKOSA-N 50007507 (R) N-(1-Benzyl-pyrrolidin-2-ylmethyl)-3-bromo-2-hydroxy-5,6-dimethoxy-benzamide::CHEMBL176804 D(2) dopamine receptor Rattus norvegicus 2.4 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007507&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894161 103920782 CHEMBL176804 ZINC13820615 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757773 COc1cc(Br)cc(C(=O)NC[C@H]2CCCN2Cc2ccccc2)c1OC InChI=1S/C21H25BrN2O3/c1-26-19-12-16(22)11-18(20(19)27-2)21(25)23-13-17-9-6-10-24(17)14-15-7-4-3-5-8-15/h3-5,7-8,11-12,17H,6,9-10,13-14H2,1-2H3,(H,23,25)/t17-/m1/s1 VQFIJOMUUDIPOY-QGZVFWFLSA-N 50007508 (R) N-(1-Benzyl-pyrrolidin-2-ylmethyl)-5-bromo-2,3-dimethoxy-benzamide::CHEMBL176458 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007508&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894156 103920783 CHEMBL176458 ZINC13820621 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757777 CCc1cc(Cl)c(OC)c(C(=O)NC[C@H]2CCCN2Cc2ccc(F)cc2)c1O InChI=1S/C22H26ClFN2O3/c1-3-15-11-18(23)21(29-2)19(20(15)27)22(28)25-12-17-5-4-10-26(17)13-14-6-8-16(24)9-7-14/h6-9,11,17,27H,3-5,10,12-13H2,1-2H3,(H,25,28)/t17-/m1/s1 JPUBWQACEPBVIP-QGZVFWFLSA-N 50007511 (R) 3-Chloro-5-ethyl-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-6-hydroxy-2-methoxy-benzamide::CHEMBL172092 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007511&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14645290 103920786 CHEMBL172092 ZINC13820609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757778 COc1cc(Br)c(OC)c(C(=O)NC[C@H]2CCCN2Cc2ccccc2)c1OC InChI=1S/C22H27BrN2O4/c1-27-18-12-17(23)20(28-2)19(21(18)29-3)22(26)24-13-16-10-7-11-25(16)14-15-8-5-4-6-9-15/h4-6,8-9,12,16H,7,10-11,13-14H2,1-3H3,(H,24,26)/t16-/m1/s1 CMKFMAOMSNBJHX-MRXNPFEDSA-N 50007513 (R) N-(1-Benzyl-pyrrolidin-2-ylmethyl)-3-bromo-2,5,6-trimethoxy-benzamide::CHEMBL171894 D(2) dopamine receptor Rattus norvegicus 1860 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894154 103920788 CHEMBL171894 ZINC13820611 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757779 COc1ccc(Br)c(OC)c1C(=O)NC[C@@H]1CCCN1Cc1ccccc1 InChI=1S/C21H25BrN2O3/c1-26-18-11-10-17(22)20(27-2)19(18)21(25)23-13-16-9-6-12-24(16)14-15-7-4-3-5-8-15/h3-5,7-8,10-11,16H,6,9,12-14H2,1-2H3,(H,23,25)/t16-/m0/s1 BGNYQRZTZGGUOK-INIZCTEOSA-N 50007512 CHEMBL367065::N-(1-Benzyl-pyrrolidin-2-ylmethyl)-3-bromo-2,6-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 16300 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007512&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894158 103920787 CHEMBL367065 ZINC13820602 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757780 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757781 COc1cc(Br)cc(C(=O)NC2CCN(Cc3ccccc3)CC2)c1OC InChI=1S/C21H25BrN2O3/c1-26-19-13-16(22)12-18(20(19)27-2)21(25)23-17-8-10-24(11-9-17)14-15-6-4-3-5-7-15/h3-7,12-13,17H,8-11,14H2,1-2H3,(H,23,25) SZYKUFQJFLQMPU-UHFFFAOYSA-N 50007514 CHEMBL75842::N-(1-Benzyl-piperidin-4-yl)-5-bromo-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15167710 103920789 CHEMBL75842 ZINC13820634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757782 COc1cccc(C(=O)NC[C@H]2CCCN2Cc2ccccc2)c1OC InChI=1S/C21H26N2O3/c1-25-19-12-6-11-18(20(19)26-2)21(24)22-14-17-10-7-13-23(17)15-16-8-4-3-5-9-16/h3-6,8-9,11-12,17H,7,10,13-15H2,1-2H3,(H,22,24)/t17-/m1/s1 JLSSMOBEJBGIRR-QGZVFWFLSA-N 50007516 (R) N-(1-Benzyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide::CHEMBL176373 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894157 103920791 CHEMBL176373 ZINC12356185 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757785 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 WGLPSCZHULDZSS-JTQLQIEISA-N 50007517 (S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-5,6-dimethoxybenzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-5,6-dimethoxy-benzamide::CHEMBL76402 D(2) dopamine receptor Rattus norvegicus 0.064000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977478 103920792 CHEMBL76402 ZINC03776019 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764273 CCCN(CCC)[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C16H23N3O/c1-3-8-18(9-4-2)13-10-12-6-5-7-14-15(12)19(11-13)16(20)17-14/h5-7,13H,3-4,8-11H2,1-2H3,(H,17,20)/t13-/m1/s1 UCZYAFAFGFTZEW-CYBMUJFWSA-N 50034354 (R)-5-Dipropylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::(R)5-Dipropylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL26181 D(2) dopamine receptor Rattus norvegicus 5.4 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034354&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131559 103942555 CHEMBL26181 ZINC03788022 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764281 Oc1cccc2C[C@@H]3[C@@H](CCN3CC=C)Cc12 InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14+/m0/s1 GNOHLPXINNYCLR-GXTWGEPZSA-N 50034334 (3aR,9aR)-1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(3aR,9aS) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL24050 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274739 103942535 CHEMBL24050 ZINC13826577 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764283 CCCN1CC[C@H]2Cc3c(O)cccc3C[C@@H]12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14+/m0/s1 DYVLYWKEJHHXOH-GXTWGEPZSA-N 50034310 (3aR,9aR)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(3aR,9aS) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(Recemic)1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL281614 D(2) dopamine receptor Rattus norvegicus >630 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034310&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275015 103942511 CHEMBL281614 ZINC13826911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764294 CCCN1C[C@@H]2[C@H]1CCc1cccc(OC)c21 InChI=1S/C15H21NO/c1-3-9-16-10-12-13(16)8-7-11-5-4-6-14(17-2)15(11)12/h4-6,12-13H,3,7-10H2,1-2H3/t12-,13-/m1/s1 WUKBUIWOSJSWRV-CHWSQXEVSA-N 50047142 (Recemic)8-Methoxy-2-propyl-1,2,2a,3,4,8b-hexahydro-naphtho[2,1-b]azete::CHEMBL283956 D(2) dopamine receptor Rattus norvegicus 329 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047142&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10399013 103977830 CHEMBL283956 ZINC13826917 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764296 CCCN1CCC2Cc3c(C[C@@H]12)cccc3OC InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13?,15-/m1/s1 HDCVYYTWHHFQGS-AWKYBWMHSA-N 50047144 (Recemic) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL278091 D(2) dopamine receptor Rattus norvegicus 877 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047144&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275155 103977832 CHEMBL278091 ZINC13826912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764301 CCCN(CCC)[C@@H]1Cc2cccc3[nH]c(=S)n(C1)c23 InChI=1S/C16H23N3S/c1-3-8-18(9-4-2)13-10-12-6-5-7-14-15(12)19(11-13)16(20)17-14/h5-7,13H,3-4,8-11H2,1-2H3,(H,17,20)/t13-/m1/s1 WEUPAXGYFOUDLZ-CYBMUJFWSA-N 50047145 (Recemic)5-Dipropylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinoline-2-thione::CHEMBL281248 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047145&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275616 103977833 CHEMBL281248 ZINC13452202 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764310 CN1C[C@H](CC2[C@H]1Cc1c(Cl)[nH]c3cccc2c13)NC(=O)C(C)(C)C InChI=1S/C20H26ClN3O/c1-20(2,3)19(25)22-11-8-13-12-6-5-7-15-17(12)14(18(21)23-15)9-16(13)24(4)10-11/h5-7,11,13,16,23H,8-10H2,1-4H3,(H,22,25)/t11-,13?,16+/m0/s1 QXOFQMUQMXGKGQ-VKCPWKDNSA-N 50047138 CHEMBL25074::N-(5-Chloro-7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-2,2-dimethyl-propionamide::SDZ-208-912::SDZ-HDC-912 D(2) dopamine receptor Rattus norvegicus 0.470000 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047138&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22849992 103977826 CHEMBL25074 ZINC13826925 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764312 CCCN(CCC)[C@@H]1Cc2cccc3ccc(=O)n(C1)c23 InChI=1S/C18H24N2O/c1-3-10-19(11-4-2)16-12-15-7-5-6-14-8-9-17(21)20(13-16)18(14)15/h5-9,16H,3-4,10-13H2,1-2H3/t16-/m1/s1 TZJYXVGLMBIOAB-MRXNPFEDSA-N 50047147 (Recemic)6-Dipropylamino-6,7-dihydro-5H-pyrido[3,2,1-ij]quinolin-3-one::CHEMBL24978 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047147&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275604 103977835 CHEMBL24978 ZINC13452286 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764315 COc1cccc2C3CCN(CC=C)[C@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13?,15-/m0/s1 ZRAGXRIXRXDXCR-WUJWULDRSA-N 50040168 (Recemic)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL276825 D(2) dopamine receptor Rattus norvegicus 99 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040168&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266623 103972228 CHEMBL276825 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764318 Oc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12 InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1 GNOHLPXINNYCLR-TZMCWYRMSA-N 50034346 (3aS,9aR) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(3aS,9aR)-1-allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL11363 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014057 103942547 CHEMBL11363 ZINC13826580 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764320 CCCN(CCC)[C@H]1CN2C(=O)NCc3cccc(C1)c23 InChI=1S/C17H25N3O/c1-3-8-19(9-4-2)15-10-13-6-5-7-14-11-18-17(21)20(12-15)16(13)14/h5-7,15H,3-4,8-12H2,1-2H3,(H,18,21)/t15-/m1/s1 GZQMSNKBMQEZJK-OAHLLOKOSA-N 50034362 (R)-6-Dipropylamino-1,2,6,7-tetrahydro-5H-pyrido[3,2,1-ij]quinazolin-3-one::(Recemic)6-Dipropylamino-1,2,6,7-tetrahydro-5H-pyrido[3,2,1-ij]quinazolin-3-one::CHEMBL24110 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034362&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44274687 103942563 CHEMBL24110 ZINC13452320 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764325 CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1 YGHLYBIUVOLKCV-SMDDNHRTSA-N 50041959 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::AJ76(+)::CHEMBL27441 D(2) dopamine receptor Rattus norvegicus 179 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122334 103973638 64117 CHEMBL27441 970 ZINC03995669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764329 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764330 Oc1cccc2[C@@H]3CCCN[C@H]3CCc12 InChI=1S/C13H17NO/c15-13-5-1-3-9-10-4-2-8-14-12(10)7-6-11(9)13/h1,3,5,10,12,14-15H,2,4,6-8H2/t10?,12-/m0/s1 RWDHALOKAOEZPC-KFJBMODSSA-N 50047143 1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol::BDBM50452346::CHEMBL56519 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047143&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9882257 103977831 CHEMBL24357CHEMBL56519 ZINC12355899 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764332 CCN(CC)C(=O)N[C@@H]1C[C@H]2[C@@H](CC3=CCc4cccc2c34)N(C)C1 InChI=1S/C21H29N3O/c1-4-24(5-2)21(25)22-16-12-18-17-8-6-7-14-9-10-15(20(14)17)11-19(18)23(3)13-16/h6-8,10,16,18-19H,4-5,9,11-13H2,1-3H3,(H,22,25)/t16-,18-,19-/m1/s1 CTVAPGCBERCRDO-BHIYHBOVSA-N 50047135 (Terguride)1,1-Diethyl-3-(7-methyl-4,6,6a,7,8,9,10,10a-octahydro-indeno[7,1-f]quinolin-9-yl)-urea::CHEMBL285341 D(2) dopamine receptor Rattus norvegicus 0.950000 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047135&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275766 103977823 CHEMBL285341 ZINC28762181 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764340 COc1cccc2C[C@@H]3C(CCN3CC=C)Cc12 InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13?,15-/m1/s1 ASEDQXVCNPLEIO-AWKYBWMHSA-N 50047141 (Recemic)1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL24129 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047141&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275658 103977829 CHEMBL24129 ZINC13826569 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764343 CCCN(CCC)[C@H]1CN2CC(=O)Nc3cccc(C1)c23 InChI=1S/C17H25N3O/c1-3-8-19(9-4-2)14-10-13-6-5-7-15-17(13)20(11-14)12-16(21)18-15/h5-7,14H,3-4,8-12H2,1-2H3,(H,18,21)/t14-/m1/s1 LFWCFBPVPREGJJ-CQSZACIVSA-N 50047150 (Recemic)6-Dipropylamino-6,7-dihydro-1H,5H-pyrido[1,2,3-de]quinoxalin-2-one::CHEMBL27399 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275615 103977838 CHEMBL27399 ZINC13452275 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764347 CN1C[C@H](CC2[C@H]1Cc1c(C)[nH]c3cccc2c13)NC(=O)C(C)(C)C InChI=1S/C21H29N3O/c1-12-15-10-18-16(14-7-6-8-17(22-12)19(14)15)9-13(11-24(18)5)23-20(25)21(2,3)4/h6-8,13,16,18,22H,9-11H2,1-5H3,(H,23,25)/t13-,16?,18+/m0/s1 ZNMWUMGOSWLWOH-HDUJFRAXSA-N 50047146 CHEMBL25013::N-(5,7-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-2,2-dimethyl-propionamide::SDZ-208-911 D(2) dopamine receptor Rattus norvegicus 0.740000 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047146&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22849991 103977834 CHEMBL25013 ZINC13826923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764355 CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C InChI=1S/C18H29NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-9,14,17H,5-6,10-13H2,1-4H3/t14-,17+/m0/s1 BTOJYCTUJJHANF-WMLDXEAASA-N 50041961 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL278751::UH-232 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604756 103973640 CHEMBL278751 ZINC03995702 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748329 CCS(=O)(=O)c1ccc(OC)c(c1)-c1ccc(CN2CCN(CC2)c2ccccc2OC)[nH]1 InChI=1S/C25H31N3O4S/c1-4-33(29,30)20-10-12-24(31-2)21(17-20)22-11-9-19(26-22)18-27-13-15-28(16-14-27)23-7-5-6-8-25(23)32-3/h5-12,17,26H,4,13-16,18H2,1-3H3 BGDYEYPXORXJHR-UHFFFAOYSA-N 50019956 1-[5-(5-Ethanesulfonyl-2-methoxy-phenyl)-1H-pyrrol-2-ylmethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL60648 D(2) dopamine receptor Rattus norvegicus 7.3 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019956&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900360 103930879 CHEMBL60648 ZINC29566166 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748330 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(=O)(=O)CC InChI=1S/C17H26N2O4S/c1-4-19-10-6-7-13(19)12-18-17(20)15-11-14(24(21,22)5-2)8-9-16(15)23-3/h8-9,11,13H,4-7,10,12H2,1-3H3,(H,18,20)/t13-/m0/s1 UNRHXEPDKXPRTM-ZDUSSCGKSA-N 50019957 5-Ethanesulfonyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-benzamide((S)-sultopride)::CHEMBL278044::Sultopride D(2) dopamine receptor Rattus norvegicus 9.30 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 29010876 103930880 CHEMBL278044 C11708 ZINC00967922 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748331 COc1ccccc1N1CCN(CCCC(=O)c2ccc(F)cc2)CC1 InChI=1S/C21H25FN2O2/c1-26-21-7-3-2-5-19(21)24-15-13-23(14-16-24)12-4-6-20(25)17-8-10-18(22)11-9-17/h2-3,5,7-11H,4,6,12-16H2,1H3 IRYFCWPNDIUQOW-UHFFFAOYSA-N 50019959 1-(4-Fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one::1-(4-Fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one(fluanisone)::CHEMBL58792::Fluanisone D(2) dopamine receptor Rattus norvegicus 2.9 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15139 103930882 CHEMBL58792 ZINC04213325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748332 CCN1CCCC1c1ccc([nH]1)-c1cc(ccc1OC)S(=O)(=O)CC InChI=1S/C19H26N2O3S/c1-4-21-12-6-7-18(21)17-10-9-16(20-17)15-13-14(25(22,23)5-2)8-11-19(15)24-3/h8-11,13,18,20H,4-7,12H2,1-3H3 PWMDANRQWZFAPB-UHFFFAOYSA-N 50005117 (racemic)5'-(5-Ethanesulfonyl-2-methoxy-phenyl)-1-ethyl-2,3,4,5-tetrahydro-1H,1'H-[2,2']bipyrrolyl::5'-(5-Ethanesulfonyl-2-methoxy-phenyl)-1-ethyl-2,3,4,5-tetrahydro-1H,1'H-[2,2']bipyrrolyl::CHEMBL277631 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005117&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 443374 103918663 CHEMBL277631 C11709 ZINC04102179 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748333 COc1ccccc1N1CCN(CCNC(=O)c2ccc(F)cc2)CC1 InChI=1S/C20H24FN3O2/c1-26-19-5-3-2-4-18(19)24-14-12-23(13-15-24)11-10-22-20(25)16-6-8-17(21)9-7-16/h2-9H,10-15H2,1H3,(H,22,25) GTATVXRFYOQYFS-UHFFFAOYSA-N 50019960 4-Fluoro-N-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-benzamide::CHEMBL58377 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13318472 103930883 CHEMBL58377 ZINC52969696 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748334 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748335 COc1ccccc1N1CCN(Cc2ccc([nH]2)-c2ccc(F)cc2)CC1 InChI=1S/C22H24FN3O/c1-27-22-5-3-2-4-21(22)26-14-12-25(13-15-26)16-19-10-11-20(24-19)17-6-8-18(23)9-7-17/h2-11,24H,12-16H2,1H3 VHRUYTMJYBYBCS-UHFFFAOYSA-N 50019961 1-[5-(4-Fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL418140 D(2) dopamine receptor Rattus norvegicus 0.910000 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900359 103930884 CHEMBL418140 ZINC29566169 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748337 OC1(CCN(Cc2ccc([nH]2)-c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C22H22ClFN2O/c23-18-5-3-17(4-6-18)22(27)11-13-26(14-12-22)15-20-9-10-21(25-20)16-1-7-19(24)8-2-16/h1-10,25,27H,11-15H2 KBCLXZNRFSYDIG-UHFFFAOYSA-N 50019958 4-(4-Chloro-phenyl)-1-[5-(4-fluoro-phenyl)-1H-pyrrol-2-ylmethyl]-piperidin-4-ol::CHEMBL59186 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900355 103930881 CHEMBL59186 ZINC29568698 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748339 CCS(=O)(=O)c1ccc(OC)c(c1)-c1ccc(CN2CCC(O)(CC2)c2ccc(Cl)cc2)[nH]1 InChI=1S/C25H29ClN2O4S/c1-3-33(30,31)21-9-11-24(32-2)22(16-21)23-10-8-20(27-23)17-28-14-12-25(29,13-15-28)18-4-6-19(26)7-5-18/h4-11,16,27,29H,3,12-15,17H2,1-2H3 FLZJOYZGXHWAFR-UHFFFAOYSA-N 50019963 4-(4-Chloro-phenyl)-1-[5-(5-ethanesulfonyl-2-methoxy-phenyl)-1H-pyrrol-2-ylmethyl]-piperidin-4-ol::CHEMBL65107 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019963&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900357 103930886 CHEMBL65107 ZINC26181321 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748345 OC1(CCN(CCNC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C20H22ClFN2O2/c21-17-5-3-16(4-6-17)20(26)9-12-24(13-10-20)14-11-23-19(25)15-1-7-18(22)8-2-15/h1-8,26H,9-14H2,(H,23,25) ZKJOQIQHASBGPA-UHFFFAOYSA-N 50019962 CHEMBL62499::N-{2-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-ethyl}-4-fluoro-benzamide D(2) dopamine receptor Rattus norvegicus 480 ChEMBL 10.1021/jm00394a028 10.7270/Q2W959R8 2889830 van Wijngaarden, I; Kruse, CG; van Hes, R; van der Heyden, JA; Tulp, MT Duphar Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019962&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900361 103930885 CHEMBL62499 ZINC26177647 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748383 CCCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m1/s1 ITXBDHMIXPKNIE-CQSZACIVSA-N 50367440 CHEMBL48219 D(2) dopamine receptor Rattus norvegicus 275 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937975 160846542 CHEMBL48219 ZINC13651755 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748385 Oc1cccc(c1)[C@H]1CCCNC1 InChI=1S/C11H15NO/c13-11-5-1-3-9(7-11)10-4-2-6-12-8-10/h1,3,5,7,10,12-13H,2,4,6,8H2/t10-/m0/s1 HYUOAVGLJXTEGX-JTQLQIEISA-N 50367441 CHEMBL8268 D(2) dopamine receptor Rattus norvegicus 435 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367441&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937952 160846543 CHEMBL8268 ZINC13651746 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748386 CCN1CCCC2C1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-16-10-4-6-12-11-5-3-7-15(17)13(11)8-9-14(12)16/h3,5,7,12,14,17H,2,4,6,8-10H2,1H3 GVOROUDOZOBZIC-UHFFFAOYSA-N 50018646 CHEMBL68952::rac-4-Ethyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol D(2) dopamine receptor Rattus norvegicus 102 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018646&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039947 103929738 CHEMBL68952 ZINC26276269 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748388 CCCN1CCCC(C1)c1ccc(O)cc1 InChI=1S/C14H21NO/c1-2-9-15-10-3-4-13(11-15)12-5-7-14(16)8-6-12/h5-8,13,16H,2-4,9-11H2,1H3 ZZGZPMSRLVMPQR-UHFFFAOYSA-N 50018648 4-(1-Propyl-piperidin-3-yl)-phenol::CHEMBL305438 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937984 103929740 CHEMBL305438 ZINC13834844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748391 CCCN1CCCC2C1CCc1cccc(O)c21 InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-14(17)9-8-12-5-3-7-15(18)16(12)13/h3,5,7,13-14,18H,2,4,6,8-11H2,1H3 PXQVPBZSEWLGIX-UHFFFAOYSA-N 50018649 (4aR,10bS)-44-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-10-ol::(4aS,10bR)-44-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-10-ol::4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-10-ol::CHEMBL412642::rac-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-10-ol D(2) dopamine receptor Rattus norvegicus 61800 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13900609 103929741 CHEMBL412642 ZINC29337667 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748396 Oc1ccc2CCC3C(CCCN3Cc3ccccc3)c2c1 InChI=1S/C20H23NO/c22-17-10-8-16-9-11-20-18(19(16)13-17)7-4-12-21(20)14-15-5-2-1-3-6-15/h1-3,5-6,8,10,13,18,20,22H,4,7,9,11-12,14H2 FGDCKQKSBUNQIJ-UHFFFAOYSA-N 50018651 CHEMBL69500::rac-4-Benzyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 3440 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039986 103929743 CHEMBL69500 ZINC26272207 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748397 CN1CCCC(C1)c1cccc(O)c1 InChI=1S/C12H17NO/c1-13-7-3-5-11(9-13)10-4-2-6-12(14)8-10/h2,4,6,8,11,14H,3,5,7,9H2,1H3 DKJJTEBJFLYIIS-UHFFFAOYSA-N 50018653 (R)-3-(1-Methyl-piperidin-3-yl)-phenol::(s)-3-(1-Methyl-piperidin-3-yl)-phenol::3-(1-Methyl-piperidin-3-yl)-phenol::CHEMBL8626 D(2) dopamine receptor Rattus norvegicus 1950 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018653&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937955 103929745 CHEMBL8626 ZINC13651749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748398 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 420 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748399 CCCN1CCCC2C1CCc1cc(O)ccc21 InChI=1S/C16H23NO/c1-2-9-17-10-3-4-15-14-7-6-13(18)11-12(14)5-8-16(15)17/h6-7,11,15-16,18H,2-5,8-10H2,1H3 BGWNOOWFGJBORE-UHFFFAOYSA-N 50018654 4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-8-ol::CHEMBL67584::rac-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-8-ol D(2) dopamine receptor Rattus norvegicus 730 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018654&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039992 103929746 CHEMBL67584 ZINC26275285 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748402 CC(C)N1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-11(2)15-8-4-6-13(10-15)12-5-3-7-14(16)9-12/h3,5,7,9,11,13,16H,4,6,8,10H2,1-2H3/t13-/m1/s1 VRNBZJJBPKLDAO-CYBMUJFWSA-N 50367442 CHEMBL424223 D(2) dopamine receptor Rattus norvegicus 355 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937970 160846544 CHEMBL424223 ZINC13651753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748404 CCCCN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m0/s1 ITXBDHMIXPKNIE-AWEZNQCLSA-N 50367443 CHEMBL45778 D(2) dopamine receptor Rattus norvegicus 2670 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937973 160846545 CHEMBL45778 ZINC13651754 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748405 CC(C)N1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-11(2)15-8-4-6-13(10-15)12-5-3-7-14(16)9-12/h3,5,7,9,11,13,16H,4,6,8,10H2,1-2H3/t13-/m0/s1 VRNBZJJBPKLDAO-ZDUSSCGKSA-N 50367444 CHEMBL432125 D(2) dopamine receptor Rattus norvegicus 12150 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937968 160846546 CHEMBL432125 ZINC13651752 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748406 CN1CCCC2C1CCc1c(O)cccc21 InChI=1S/C14H19NO/c1-15-9-3-5-11-10-4-2-6-14(16)12(10)7-8-13(11)15/h2,4,6,11,13,16H,3,5,7-9H2,1H3 DGCMNMVRIBXKGJ-UHFFFAOYSA-N 50018656 4-Methyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol::CHEMBL56618::rac-4-Methyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol D(2) dopamine receptor Rattus norvegicus 114 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018656&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126571 103929748 CHEMBL56618 ZINC29555542 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748407 CCCCN1CCCC2C1CCc1ccc(OC)cc21 InChI=1S/C18H27NO/c1-3-4-11-19-12-5-6-16-17-13-15(20-2)9-7-14(17)8-10-18(16)19/h7,9,13,16,18H,3-6,8,10-12H2,1-2H3 KGSDZOIPSQXEKU-UHFFFAOYSA-N 50018657 CHEMBL68989::rac-4-Butyl-9-methoxy-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline D(2) dopamine receptor Rattus norvegicus 3840 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018657&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039974 103929749 CHEMBL68989 ZINC26269062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748413 CCN1CCCC2C1CCc1ccc(O)cc21 InChI=1S/C15H21NO/c1-2-16-9-3-4-13-14-10-12(17)7-5-11(14)6-8-15(13)16/h5,7,10,13,15,17H,2-4,6,8-9H2,1H3 SVIIYVRLTJRIIR-UHFFFAOYSA-N 50018660 CHEMBL305793::rac-4-Ethyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018660&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039972 103929752 CHEMBL305793 ZINC26291923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748415 Oc1cccc2C3CCCNC3CCc12 InChI=1S/C13H17NO/c15-13-5-1-3-9-10-4-2-8-14-12(10)7-6-11(9)13/h1,3,5,10,12,14-15H,2,4,6-8H2 RWDHALOKAOEZPC-UHFFFAOYSA-N 50018647 (R,R)-1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol::(S,S)-1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol::CHEMBL302244::rac-1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-7-ol D(2) dopamine receptor Rattus norvegicus 7500 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039950 103929739 CHEMBL302244 ZINC12355899 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750154 CN1CCc2cc(Cl)c(O)cc2[C@H]1c1ccccc1 InChI=1S/C16H16ClNO/c1-18-8-7-12-9-14(17)15(19)10-13(12)16(18)11-5-3-2-4-6-11/h2-6,9-10,16,19H,7-8H2,1H3/t16-/m1/s1 AVXGCGYACIYZAR-MRXNPFEDSA-N 50038350 (R)-6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::CHEMBL293158 D(2) dopamine receptor Rattus norvegicus 19200 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198585 103945769 CHEMBL293158 ZINC13675796 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750155 CN1CC(c2ccccc2)c2cc(O)c(Cl)cc2C1 InChI=1S/C16H16ClNO/c1-18-9-12-7-15(17)16(19)8-13(12)14(10-18)11-5-3-2-4-6-11/h2-8,14,19H,9-10H2,1H3 QMEAXKMTOSHGKG-UHFFFAOYSA-N 50022053 1-Benzyl-6-chloro-2-methyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::7-Chloro-2-methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-6-ol::CHEMBL299056 D(2) dopamine receptor Rattus norvegicus 522 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198596 103932734 CHEMBL299056 ZINC13675874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750156 CN1CCc2cc(Cl)c(O)cc2C1Cc1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-10-15(18)17(20)11-14(13)16(19)9-12-5-3-2-4-6-12/h2-6,10-11,16,20H,7-9H2,1H3 JHDHNKDQVCVUJN-UHFFFAOYSA-N 50022052 1-Benzyl-6-chloro-2-methyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::1-Benzyl-6-chloro-7-hydroxy-N-methyl-1,2,3,4-tetrahydroisoquinoline::CHEMBL60706 D(2) dopamine receptor Rattus norvegicus 287 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198586 103932733 CHEMBL60706 ZINC12355995 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750162 Oc1cc2[C@H](NCCc2cc1Cl)c1ccccc1 InChI=1S/C15H14ClNO/c16-13-8-11-6-7-17-15(12(11)9-14(13)18)10-4-2-1-3-5-10/h1-5,8-9,15,17-18H,6-7H2/t15-/m1/s1 VXQGSKLYCJFAKI-OAHLLOKOSA-N 50367600 CHEMBL1788322 D(2) dopamine receptor Rattus norvegicus 26300 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367600&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198589 160846702 CHEMBL1788322 ZINC13739903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750165 CCCN1CCc2cc(Cl)c(O)cc2[C@@H]1c1ccccc1 InChI=1S/C18H20ClNO/c1-2-9-20-10-8-14-11-16(19)17(21)12-15(14)18(20)13-6-4-3-5-7-13/h3-7,11-12,18,21H,2,8-10H2,1H3/t18-/m0/s1 UCVFZVSEYSSSHP-SFHVURJKSA-N 50367601 CHEMBL293828 D(2) dopamine receptor Rattus norvegicus 1900 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198601 160846703 CHEMBL293828 ZINC13675924 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750166 Oc1cc2[C@@H](NCCc2cc1Cl)c1ccccc1 InChI=1S/C15H14ClNO/c16-13-8-11-6-7-17-15(12(11)9-14(13)18)10-4-2-1-3-5-10/h1-5,8-9,15,17-18H,6-7H2/t15-/m0/s1 VXQGSKLYCJFAKI-HNNXBMFYSA-N 50367602 CHEMBL65397 D(2) dopamine receptor Rattus norvegicus 3750 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198590 160846704 CHEMBL65397 ZINC13739904 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750167 CN1CCc2cc(Cl)c(O)cc2C1c1ccccc1 InChI=1S/C16H16ClNO/c1-18-8-7-12-9-14(17)15(19)10-13(12)16(18)11-5-3-2-4-6-11/h2-6,9-10,16,19H,7-8H2,1H3 AVXGCGYACIYZAR-UHFFFAOYSA-N 50022051 1-Phenyl-6-chloro-7-hydroxy-N-methyl-1,2,3,4-tetrahydroisoquinoline::6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::CHEMBL57579 D(2) dopamine receptor Rattus norvegicus 915 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198584 103932732 CHEMBL57579 ZINC13675796 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750171 Oc1cc2C(CNCc2cc1Cl)c1ccccc1 InChI=1S/C15H14ClNO/c16-14-6-11-8-17-9-13(12(11)7-15(14)18)10-4-2-1-3-5-10/h1-7,13,17-18H,8-9H2 MGAQDUSMABIJCH-UHFFFAOYSA-N 50022054 7-Chloro-4-phenyl-1,2,3,4-tetrahydro-isoquinolin-6-ol::CHEMBL57988 D(2) dopamine receptor Rattus norvegicus 3620 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50022054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50022054&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14198593 103932735 CHEMBL57988 ZINC13675870 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750172 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 900 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750177 Oc1cc2C(CNCCc2cc1Cl)c1ccccc1 InChI=1S/C16H16ClNO/c17-15-8-12-6-7-18-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,18-19H,6-7,10H2 ZVKJSJAERRMBMR-UHFFFAOYSA-N 50004796 8-Chloro-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol; hydrobromide::CHEMBL292418::CHEMBL540857 D(2) dopamine receptor Rattus norvegicus 676 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 146266 103918343 CHEMBL540857CHEMBL292418 ZINC02539831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50750180 CN1CCc2cc(Cl)c(O)cc2[C@@H]1c1ccccc1 InChI=1S/C16H16ClNO/c1-18-8-7-12-9-14(17)15(19)10-13(12)16(18)11-5-3-2-4-6-11/h2-6,9-10,16,19H,7-8H2,1H3/t16-/m0/s1 AVXGCGYACIYZAR-INIZCTEOSA-N 50038349 (S)-6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::6-Chloro-2-methyl-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol::CHEMBL303993 D(2) dopamine receptor Rattus norvegicus 1850 ChEMBL 10.1021/jm00118a012 10.7270/Q20002PD 3050089 Charifson, PS; Wyrick, SD; Hoffman, AJ; Simmons, RM; Bowen, JP; McDougald, DL; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10107367 103945768 CHEMBL303993 ZINC13675794 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50753565 CCN1CCC[C@H]1CNC(=O)c1cc2cc(Br)ccc2cc1OC InChI=1S/C19H23BrN2O2/c1-3-22-8-4-5-16(22)12-21-19(23)17-10-14-9-15(20)7-6-13(14)11-18(17)24-2/h6-7,9-11,16H,3-5,8,12H2,1-2H3,(H,21,23)/t16-/m0/s1 YEGVCAFFWCDEDG-INIZCTEOSA-N 50012971 7-Bromo-3-methoxy-naphthalene-2-carboxylic acid (1-ethyl-pyrrolidin-2-ylmethyl)-amide::CHEMBL49898 D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1021/jm00163a029 10.7270/Q2280860 2136916 Murphy, RA; Kung, HF; Kung, MP; Billings, J University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012971&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14528109 103925219 CHEMBL49898 ZINC29470937 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757786 COc1c(Cl)cc(Cl)c(O)c1C(=O)NC[C@H]1CCCN1Cc1ccc(F)cc1 InChI=1S/C20H21Cl2FN2O3/c1-28-19-16(22)9-15(21)18(26)17(19)20(27)24-10-14-3-2-8-25(14)11-12-4-6-13(23)7-5-12/h4-7,9,14,26H,2-3,8,10-11H2,1H3,(H,24,27)/t14-/m1/s1 QMFFLCVFHSNHOX-CQSZACIVSA-N 50007519 (R) 3,5-Dichloro-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2-hydroxy-6-methoxy-benzamide::CHEMBL173717 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894160 103920794 CHEMBL173717 ZINC13820607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757787 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.920000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757788 COc1c(Cl)cc(Cl)c(OC)c1C(=O)NC[C@H]1CCCN1Cc1ccc(F)cc1 InChI=1S/C21H23Cl2FN2O3/c1-28-19-16(22)10-17(23)20(29-2)18(19)21(27)25-11-15-4-3-9-26(15)12-13-5-7-14(24)8-6-13/h5-8,10,15H,3-4,9,11-12H2,1-2H3,(H,25,27)/t15-/m1/s1 QTUBZRUYBKRCAE-OAHLLOKOSA-N 50007520 (R) 3,5-Dichloro-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2,6-dimethoxy-benzamide::CHEMBL262403 D(2) dopamine receptor Rattus norvegicus 2380 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894153 103920795 CHEMBL262403 ZINC13820605 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757789 COc1cc(Br)cc(C(=O)NC[C@@H]2CCCN2Cc2ccc(F)cc2)c1OC InChI=1S/C21H24BrFN2O3/c1-27-19-11-15(22)10-18(20(19)28-2)21(26)24-12-17-4-3-9-25(17)13-14-5-7-16(23)8-6-14/h5-8,10-11,17H,3-4,9,12-13H2,1-2H3,(H,24,26)/t17-/m0/s1 OHMIBGFTDCPQGJ-KRWDZBQOSA-N 50007521 5-Bromo-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2,3-dimethoxy-benzamide (NCQ115)::CHEMBL1204286::CHEMBL73683 D(2) dopamine receptor Rattus norvegicus 126 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007521&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14880710 103920796 CHEMBL1204286CHEMBL73683 ZINC13820623 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757792 CCN1CCC[C@H]1CNC(=O)c1cccc(OC)c1OC InChI=1S/C16H24N2O3/c1-4-18-10-6-7-12(18)11-17-16(19)13-8-5-9-14(20-2)15(13)21-3/h5,8-9,12H,4,6-7,10-11H2,1-3H3,(H,17,19)/t12-/m0/s1 RCZDXFJAMRSBKF-LBPRGKRZSA-N 50007523 CHEMBL295621::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 52 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007523&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14416349 103920798 CHEMBL295621 ZINC13820636 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757793 COc1cccc(C(=O)NC2CCN(Cc3ccccc3)CC2)c1OC InChI=1S/C21H26N2O3/c1-25-19-10-6-9-18(20(19)26-2)21(24)22-17-11-13-23(14-12-17)15-16-7-4-3-5-8-16/h3-10,17H,11-15H2,1-2H3,(H,22,24) CFOLDWHTVLAWTI-UHFFFAOYSA-N 50007525 CHEMBL123282::N-(1-Benzyl-piperidin-4-yl)-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 6.3 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13314232 103920800 CHEMBL123282 ZINC13820638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757795 COc1c(Cl)cc(Cl)c(O)c1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H22Cl2N2O3/c1-27-19-16(22)11-15(21)18(25)17(19)20(26)23-14-7-9-24(10-8-14)12-13-5-3-2-4-6-13/h2-6,11,14,25H,7-10,12H2,1H3,(H,23,26) KCEKRQOLTANGPT-UHFFFAOYSA-N 50007528 CHEMBL366766::N-(1-Benzyl-piperidin-4-yl)-3,5-dichloro-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 5.4 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15167702 103920803 CHEMBL366766 ZINC13820629 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757796 COc1cc(Br)cc(C(=O)NC[C@H]2CCCN2Cc2ccc(F)cc2)c1OC InChI=1S/C21H24BrFN2O3/c1-27-19-11-15(22)10-18(20(19)28-2)21(26)24-12-17-4-3-9-25(17)13-14-5-7-16(23)8-6-14/h5-8,10-11,17H,3-4,9,12-13H2,1-2H3,(H,24,26)/t17-/m1/s1 OHMIBGFTDCPQGJ-QGZVFWFLSA-N 50007529 (R) 5-Bromo-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2,3-dimethoxy-benzamide::CHEMBL177762 D(2) dopamine receptor Rattus norvegicus 0.650000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007529&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14880708 103920804 CHEMBL177762 ZINC03785274 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757797 COc1cc(Br)c(OC)c(C(=O)NC[C@H]2CCCN2Cc2ccc(F)cc2)c1O InChI=1S/C21H24BrFN2O4/c1-28-17-10-16(22)20(29-2)18(19(17)26)21(27)24-11-15-4-3-9-25(15)12-13-5-7-14(23)8-6-13/h5-8,10,15,26H,3-4,9,11-12H2,1-2H3,(H,24,27)/t15-/m1/s1 GANLYZUTVYDAQW-OAHLLOKOSA-N 50007526 (R) 3-Bromo-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-6-hydroxy-2,5-dimethoxy-benzamide::CHEMBL174606 D(2) dopamine receptor Rattus norvegicus 124 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007526&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894164 103920801 CHEMBL174606 ZINC13820619 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757798 COc1cc(Br)c(O)c(C(=O)NC2CCN(Cc3ccccc3)CC2)c1OC InChI=1S/C21H25BrN2O4/c1-27-17-12-16(22)19(25)18(20(17)28-2)21(26)23-15-8-10-24(11-9-15)13-14-6-4-3-5-7-14/h3-7,12,15,25H,8-11,13H2,1-2H3,(H,23,26) HUAOWHVSGILVDD-UHFFFAOYSA-N 50007527 CHEMBL172536::N-(1-Benzyl-piperidin-4-yl)-3-bromo-2-hydroxy-5,6-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.360000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007527&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15167744 103920802 CHEMBL172536 ZINC13820632 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757800 COc1cc(Br)c(OC)c(C(=O)NC[C@H]2CCCN2Cc2ccc(F)cc2)c1OC InChI=1S/C22H26BrFN2O4/c1-28-18-11-17(23)20(29-2)19(21(18)30-3)22(27)25-12-16-5-4-10-26(16)13-14-6-8-15(24)9-7-14/h6-9,11,16H,4-5,10,12-13H2,1-3H3,(H,25,27)/t16-/m1/s1 KNDXQXFWDHGPRX-MRXNPFEDSA-N 50007530 (R) 3-Bromo-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2,5,6-trimethoxy-benzamide::CHEMBL367751 D(2) dopamine receptor Rattus norvegicus 2210 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894155 103920805 CHEMBL367751 ZINC13820613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757801 COc1c(Cl)cc(Cl)c(OC)c1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C21H24Cl2N2O3/c1-27-19-16(22)12-17(23)20(28-2)18(19)21(26)24-15-8-10-25(11-9-15)13-14-6-4-3-5-7-14/h3-7,12,15H,8-11,13H2,1-2H3,(H,24,26) WLRZQJSTYVWOMK-UHFFFAOYSA-N 50007532 CHEMBL172865::N-(1-Benzyl-piperidin-4-yl)-3,5-dichloro-2,6-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 3450 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13202169 103920807 CHEMBL172865 ZINC13820625 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757803 COc1ccc(Br)c(O)c1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H23BrN2O3/c1-26-17-8-7-16(21)19(24)18(17)20(25)22-15-9-11-23(12-10-15)13-14-5-3-2-4-6-14/h2-8,15,24H,9-13H2,1H3,(H,22,25) LEKQMKPPEAGNOX-UHFFFAOYSA-N 50007531 CHEMBL174472::N-(1-Benzyl-piperidin-4-yl)-3-bromo-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15167739 103920806 CHEMBL174472 ZINC13820627 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757804 CCc1cc(Cl)c(OC)c(C(=O)NC2CCN(Cc3ccccc3)CC2)c1O InChI=1S/C22H27ClN2O3/c1-3-16-13-18(23)21(28-2)19(20(16)26)22(27)24-17-9-11-25(12-10-17)14-15-7-5-4-6-8-15/h4-8,13,17,26H,3,9-12,14H2,1-2H3,(H,24,27) KNDROBMWIFWNJI-UHFFFAOYSA-N 50007533 CHEMBL173536::N-(1-Benzyl-piperidin-4-yl)-3-chloro-5-ethyl-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 9.4 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007533&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15167754 103920808 CHEMBL173536 ZINC13820630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757808 COc1ccc(Br)c(O)c1C(=O)NCC1CCCN1Cc1ccccc1 InChI=1S/C20H23BrN2O3/c1-26-17-10-9-16(21)19(24)18(17)20(25)22-12-15-8-5-11-23(15)13-14-6-3-2-4-7-14/h2-4,6-7,9-10,15,24H,5,8,11-13H2,1H3,(H,22,25) MBIMLBIDRSPVIF-UHFFFAOYSA-N 50007515 (R)N-(1-Benzyl-pyrrolidin-2-ylmethyl)-3-bromo-2-hydroxy-6-methoxy-benzamide::(R/S)N-(1-Benzyl-pyrrolidin-2-ylmethyl)-3-bromo-2-hydroxy-6-methoxy-benzamide::(S) N-(1-Benzyl-pyrrolidin-2-ylmethyl)-3-bromo-2-hydroxy-6-methoxy-benzamide::CHEMBL177436 D(2) dopamine receptor Rattus norvegicus 36 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894148 103920790 CHEMBL177436 ZINC13820600 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757809 CCN1CCC[C@H]1CNC(=O)c1cc(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 QAECXZXKVURFMR-LBPRGKRZSA-N 50007522 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide::5-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2,3-dimethoxybenzamide::CHEMBL289330 D(2) dopamine receptor Rattus norvegicus 0.018000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9907436 103920797 CHEMBL289330 ZINC03780178 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50757810 COc1cc(Br)c(O)c(C(=O)NC[C@H]2CCCN2Cc2ccc(F)cc2)c1OC InChI=1S/C21H24BrFN2O4/c1-28-17-10-16(22)19(26)18(20(17)29-2)21(27)24-11-15-4-3-9-25(15)12-13-5-7-14(23)8-6-13/h5-8,10,15,26H,3-4,9,11-12H2,1-2H3,(H,24,27)/t15-/m1/s1 JPFKUHKRYXOWGK-OAHLLOKOSA-N 50007510 (R) 3-Bromo-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2-hydroxy-5,6-dimethoxy-benzamide::CHEMBL435670 D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894163 103920785 CHEMBL435670 ZINC13820617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50759742 CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3 ASGIQUHBAVIOTI-UHFFFAOYSA-N 50000069 CHEMBL20377::[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-ethyl)-amine D(2) dopamine receptor Rattus norvegicus 1112 ChEMBL 10.1021/jm00090a012 10.7270/Q24B31ZD 1319493 de Costa, B; Radesca, L; Dominguez, C; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000069&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126388 103914767 CHEMBL20377 ZINC22441678 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50759750 FCCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C15H21Cl2FN2/c16-14-3-2-13(12-15(14)17)4-7-20-10-8-19(9-11-20)6-1-5-18/h2-3,12H,1,4-11H2 SYLQLALDNDYPPG-UHFFFAOYSA-N 50000773 1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-(3-fluoro-propyl)-piperazine::CHEMBL70540 D(2) dopamine receptor Rattus norvegicus 11993 ChEMBL 10.1021/jm00090a012 10.7270/Q24B31ZD 1319493 de Costa, B; Radesca, L; Dominguez, C; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000773&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 594236 103915317 CHEMBL70540 ZINC22875204 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50759753 CN(CCN1CCCC1)CCc1cc(Cl)c(Cl)cc1I InChI=1S/C15H21Cl2IN2/c1-19(8-9-20-5-2-3-6-20)7-4-12-10-13(16)14(17)11-15(12)18/h10-11H,2-9H2,1H3 YREMDYBBCZPYRE-UHFFFAOYSA-N 50000771 CHEMBL71049::[2-(4,5-Dichloro-2-iodo-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-ethyl)-amine D(2) dopamine receptor Rattus norvegicus 1311 ChEMBL 10.1021/jm00090a012 10.7270/Q24B31ZD 1319493 de Costa, B; Radesca, L; Dominguez, C; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15175722 103915315 CHEMBL71049 ZINC22924996 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50759757 FCCCN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 InChI=1S/C17H25Cl2FN2/c18-16-5-4-15(14-17(16)19)6-11-22(10-3-7-20)13-12-21-8-1-2-9-21/h4-5,14H,1-3,6-13H2 FFENYFYUTQOUSD-UHFFFAOYSA-N 50000772 CHEMBL70861::[2-(3,4-Dichloro-phenyl)-ethyl]-(3-fluoro-propyl)-(2-pyrrolidin-1-yl-ethyl)-amine D(2) dopamine receptor Rattus norvegicus 3111 ChEMBL 10.1021/jm00090a012 10.7270/Q24B31ZD 1319493 de Costa, B; Radesca, L; Dominguez, C; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000772&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 558843 103915316 CHEMBL70861 ZINC22924987 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50759763 CCCN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C15H22Cl2N2/c1-2-6-18-8-10-19(11-9-18)7-5-13-3-4-14(16)15(17)12-13/h3-4,12H,2,5-11H2,1H3 LUKGVLGXYXKAAS-UHFFFAOYSA-N 50000776 1-[2-(3,4-Dichloro-phenyl)-ethyl]-4-propyl-piperazine::CHEMBL70807 D(2) dopamine receptor Rattus norvegicus 2902 ChEMBL 10.1021/jm00090a012 10.7270/Q24B31ZD 1319493 de Costa, B; Radesca, L; Dominguez, C; Di Paolo, L; Bowen, WD National Institute of Diabetes and Digestive and Kidney Diseases http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000776&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 587944 103915320 CHEMBL70807 ZINC22778697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762102 CCCN(CCc1ccc(O)cc1)CCc1ccc(Cl)c(O)c1 InChI=1S/C19H24ClNO2/c1-2-11-21(12-9-15-3-6-17(22)7-4-15)13-10-16-5-8-18(20)19(23)14-16/h3-8,14,22-23H,2,9-13H2,1H3 TVBDCIGJBCAZFA-UHFFFAOYSA-N 50002309 2-Chloro-5-(2-{[2-(4-hydroxy-phenyl)-ethyl]-propyl-amino}-ethyl)-phenol; hydrobromide::CHEMBL555427 D(2) dopamine receptor Rattus norvegicus 900 ChEMBL 10.1021/jm00101a018 10.7270/Q2WH2QMC 1360027 Claudi, F; Giorgioni, G; Di Stefano, A; Abbracchio, MP; Paoletti, AM; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002309&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9979207 103916615 CHEMBL555427 ZINC13730714 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762103 CCCN(CCc1ccccc1)CCc1cccc(O)c1 InChI=1S/C19H25NO/c1-2-13-20(14-11-17-7-4-3-5-8-17)15-12-18-9-6-10-19(21)16-18/h3-10,16,21H,2,11-15H2,1H3 QUZUPTMNMJTYGL-UHFFFAOYSA-N 50002310 3-[2-(Phenethyl-propyl-amino)-ethyl]-phenol; hydrobromide::CHEMBL1188090::CHEMBL545783 D(2) dopamine receptor Rattus norvegicus 750 ChEMBL 10.1021/jm00101a018 10.7270/Q2WH2QMC 1360027 Claudi, F; Giorgioni, G; Di Stefano, A; Abbracchio, MP; Paoletti, AM; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002310&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 114876 103916616 CHEMBL545783CHEMBL1188090 ZINC05833398 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762104 CCCN(CCc1ccccc1)CCc1ccc(Cl)c(O)c1 InChI=1S/C19H24ClNO/c1-2-12-21(13-10-16-6-4-3-5-7-16)14-11-17-8-9-18(20)19(22)15-17/h3-9,15,22H,2,10-14H2,1H3 IBYPWAJDLFCYIC-UHFFFAOYSA-N 50002311 2-Chloro-5-[2-(phenethyl-propyl-amino)-ethyl]-phenol; hydrobromide::CHEMBL553399 D(2) dopamine receptor Rattus norvegicus 1390 ChEMBL 10.1021/jm00101a018 10.7270/Q2WH2QMC 1360027 Claudi, F; Giorgioni, G; Di Stefano, A; Abbracchio, MP; Paoletti, AM; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002311&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10408602 103916617 CHEMBL553399 ZINC13730708 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762105 CCCN(CCC)CCc1ccc(Cl)c(O)c1 InChI=1S/C14H22ClNO/c1-3-8-16(9-4-2)10-7-12-5-6-13(15)14(17)11-12/h5-6,11,17H,3-4,7-10H2,1-2H3 PYOHWYNSWRWGMQ-UHFFFAOYSA-N 50002312 2-Chloro-5-(2-dipropylamino-ethyl)-phenol; hydrobromide::CHEMBL554950 D(2) dopamine receptor Rattus norvegicus 12900 ChEMBL 10.1021/jm00101a018 10.7270/Q2WH2QMC 1360027 Claudi, F; Giorgioni, G; Di Stefano, A; Abbracchio, MP; Paoletti, AM; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002312&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10246432 103916618 CHEMBL554950 ZINC13730705 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762107 CCCN(CCc1cccc(O)c1)CCc1ccc(Cl)c(O)c1 InChI=1S/C19H24ClNO2/c1-2-10-21(11-8-15-4-3-5-17(22)13-15)12-9-16-6-7-18(20)19(23)14-16/h3-7,13-14,22-23H,2,8-12H2,1H3 LPRDBSOZZZGOEA-UHFFFAOYSA-N 50002313 2-Chloro-5-(2-{[2-(3-hydroxy-phenyl)-ethyl]-propyl-amino}-ethyl)-phenol; hydrobromide::CHEMBL541096 D(2) dopamine receptor Rattus norvegicus 730 ChEMBL 10.1021/jm00101a018 10.7270/Q2WH2QMC 1360027 Claudi, F; Giorgioni, G; Di Stefano, A; Abbracchio, MP; Paoletti, AM; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002313&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10024827 103916619 CHEMBL541096 ZINC13730711 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762108 NCCc1ccc(Cl)c(O)c1 InChI=1S/C8H10ClNO/c9-7-2-1-6(3-4-10)5-8(7)11/h1-2,5,11H,3-4,10H2 PMBDMPWZYMGZDT-UHFFFAOYSA-N 50002315 5-(2-Amino-ethyl)-2-chloro-phenol; hydrobromide::CHEMBL553361 D(2) dopamine receptor Rattus norvegicus 26300 ChEMBL 10.1021/jm00101a018 10.7270/Q2WH2QMC 1360027 Claudi, F; Giorgioni, G; Di Stefano, A; Abbracchio, MP; Paoletti, AM; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002315&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 197505 103916621 CHEMBL553361 ZINC03644407 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762110 CCCN(CCCc1ccc(O)cc1)CCc1ccc(Cl)c(O)c1 InChI=1S/C20H26ClNO2/c1-2-12-22(13-3-4-16-5-8-18(23)9-6-16)14-11-17-7-10-19(21)20(24)15-17/h5-10,15,23-24H,2-4,11-14H2,1H3 LAZITDORYYQLST-UHFFFAOYSA-N 50002314 2-Chloro-5-(2-{[3-(4-hydroxy-phenyl)-propyl]-propyl-amino}-ethyl)-phenol; hydrobromide::CHEMBL543914 D(2) dopamine receptor Rattus norvegicus 850 ChEMBL 10.1021/jm00101a018 10.7270/Q2WH2QMC 1360027 Claudi, F; Giorgioni, G; Di Stefano, A; Abbracchio, MP; Paoletti, AM; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10048240 103916620 CHEMBL543914 ZINC13730717 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762115 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 3500 ChEMBL 10.1021/jm00101a018 10.7270/Q2WH2QMC 1360027 Claudi, F; Giorgioni, G; Di Stefano, A; Abbracchio, MP; Paoletti, AM; Balduini, W University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762132 Fc1ccc(cc1)C(CCCN1CCN(CC1)c1ncc(F)cn1)C#N InChI=1S/C19H21F2N5/c20-17-5-3-15(4-6-17)16(12-22)2-1-7-25-8-10-26(11-9-25)19-23-13-18(21)14-24-19/h3-6,13-14,16H,1-2,7-11H2 PLLXGFQSUXATSU-UHFFFAOYSA-N 50002317 2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-pentanenitrile::CHEMBL443482 D(2) dopamine receptor Rattus norvegicus 1880 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002317&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473524 103916623 CHEMBL443482 ZINC13730930 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762136 CCC(O)(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C20H26F2N4O/c1-2-20(27,16-4-6-17(21)7-5-16)8-3-9-25-10-12-26(13-11-25)19-23-14-18(22)15-24-19/h4-7,14-15,27H,2-3,8-13H2,1H3 WZAOXRLRCQESBE-UHFFFAOYSA-N 50002321 3-(4-Fluoro-phenyl)-6-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-hexan-3-ol::CHEMBL141523 D(2) dopamine receptor Rattus norvegicus 3750 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10407185 103916627 CHEMBL141523 ZINC13730915 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762140 OC(CCCN1CCN(CC1)c1ncc(F)cn1)(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C24H25F3N4O/c25-20-6-2-18(3-7-20)24(32,19-4-8-21(26)9-5-19)10-1-11-30-12-14-31(15-13-30)23-28-16-22(27)17-29-23/h2-9,16-17,32H,1,10-15H2 PEBXNNOYEDSSON-UHFFFAOYSA-N 50002326 1,1-Bis-(4-fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::CHEMBL138186 D(2) dopamine receptor Rattus norvegicus 940 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10321125 103916632 CHEMBL138186 ZINC13730918 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762141 Fc1ccc(\C=C(/CCN2CCN(CC2)c2ncccn2)c2ccc(F)cc2)cc1 InChI=1S/C24H24F2N4/c25-22-6-2-19(3-7-22)18-21(20-4-8-23(26)9-5-20)10-13-29-14-16-30(17-15-29)24-27-11-1-12-28-24/h1-9,11-12,18H,10,13-17H2/b21-18+ GWZMKOHHPGERJI-DYTRJAOYSA-N 50002325 2-{4-[3,4-Bis-(4-fluoro-phenyl)-but-3-enyl]-piperazin-1-yl}-pyrimidine::CHEMBL342484 D(2) dopamine receptor Rattus norvegicus 1700 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44359980 103916631 CHEMBL342484 ZINC27522732 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762143 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762146 OC(CCCN1CCN(CC1)c1ncccn1)(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C24H26F2N4O/c25-21-7-3-19(4-8-21)24(31,20-5-9-22(26)10-6-20)11-1-14-29-15-17-30(18-16-29)23-27-12-2-13-28-23/h2-10,12-13,31H,1,11,14-18H2 IIMKXNWBKIJTAL-UHFFFAOYSA-N 50002318 1,1-Bis-(4-fluoro-phenyl)-4-(4-pyrimidin-2-yl-piperazin-1-yl)-butan-1-ol::CHEMBL140831 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002318&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10002462 103916624 CHEMBL140831 ZINC12356404 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762148 CCC(O)(CCCN1CCN(CC1)c1ncccn1)c1ccc(F)cc1 InChI=1S/C20H27FN4O/c1-2-20(26,17-5-7-18(21)8-6-17)9-3-12-24-13-15-25(16-14-24)19-22-10-4-11-23-19/h4-8,10-11,26H,2-3,9,12-16H2,1H3 YYTBMHOKZFPJNJ-UHFFFAOYSA-N 50002327 3-(4-Fluoro-phenyl)-6-(4-pyrimidin-2-yl-piperazin-1-yl)-hexan-3-ol::CHEMBL334934 D(2) dopamine receptor Rattus norvegicus 415 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10428490 103916633 CHEMBL334934 ZINC13730909 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762149 O[C@@H](CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2/t17-/m0/s1 ZXUYYZPJUGQHLQ-KRWDZBQOSA-N 50036736 (S)-1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::CHEMBL129263 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036736&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020651 103944377 CHEMBL129263 ZINC00013635 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762151 Fc1ccc(cc1)C(CCCN1CCN(CC1)c1ncc(F)cn1)N=O InChI=1S/C18H21F2N5O/c19-15-5-3-14(4-6-15)17(23-26)2-1-7-24-8-10-25(11-9-24)18-21-12-16(20)13-22-18/h3-6,12-13,17H,1-2,7-11H2 DAVXPKZMOAKGGT-UHFFFAOYSA-N 50002329 1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-one oxime::CHEMBL141226 D(2) dopamine receptor Rattus norvegicus 1860 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002329&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 91928637 103916635 CHEMBL141226 ZINC13730933 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762153 OC(CCCN1CCN(CC1)c1ncc(Cl)cn1)c1ccc(F)cc1 InChI=1S/C18H22ClFN4O/c19-15-12-21-18(22-13-15)24-10-8-23(9-11-24)7-1-2-17(25)14-3-5-16(20)6-4-14/h3-6,12-13,17,25H,1-2,7-11H2 RZBSYNVZZGXXQR-UHFFFAOYSA-N 50002330 4-[4-(5-Chloro-pyrimidin-2-yl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-butan-1-ol::CHEMBL139595 D(2) dopamine receptor Rattus norvegicus 5660 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11726318 103916636 CHEMBL139595 ZINC13730867 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50762155 Fc1ccc(cc1)C(=O)CCN1CCN(CC1)c1ncc(F)cn1 InChI=1S/C17H18F2N4O/c18-14-3-1-13(2-4-14)16(24)5-6-22-7-9-23(10-8-22)17-20-11-15(19)12-21-17/h1-4,11-12H,5-10H2 BGPJHKCGFSWCLH-UHFFFAOYSA-N 50002333 1-(4-Fluoro-phenyl)-3-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-propan-1-one::CHEMBL139711 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00102a002 10.7270/Q2H70GDV 1361578 Yevich, JP; New, JS; Lobeck, WG; Dextraze, P; Bernstein, E; Taylor, DP; Yocca, FD; Eison, MS; Temple, DL Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002333&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10042372 103916639 CHEMBL139711 ZINC13730855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764357 Oc1cccc2C[C@@H]3C(CCN3CC=C)Cc12 InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12?,14-/m1/s1 GNOHLPXINNYCLR-TYZXPVIJSA-N 50047136 (Recemic)1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL278285 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047136&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275362 103977824 CHEMBL278285 ZINC13826580 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764359 CCCN1CCC2C1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3 SHOJVFLWKSRVPH-UHFFFAOYSA-N 50040174 (Recemic)3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL10207 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266612 103972234 CHEMBL10207 ZINC26006261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764365 COc1cccc2C3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13?,15-/m1/s1 ZRAGXRIXRXDXCR-AWKYBWMHSA-N 50040170 (Recemic)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL10570 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266689 103972230 CHEMBL10570 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764373 CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1 DYVLYWKEJHHXOH-TZMCWYRMSA-N 50034352 (3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(3aS,9aR)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL11066 D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105311 103942553 CHEMBL11066 ZINC13826575 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764375 COc1cccc2[C@@H]3CCN(CC=C)[C@@H]3CCc12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-12-5-4-6-16(18-2)14(12)7-8-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m0/s1 ZRAGXRIXRXDXCR-DZGCQCFKSA-N 50034341 (3aR,9bS)-3-allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)3-Allyl-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL280955 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466962 103942542 CHEMBL280955 ZINC00004906 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764382 CCCN1CCC2Cc3c(O)cccc3C[C@@H]12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12?,14-/m1/s1 DYVLYWKEJHHXOH-TYZXPVIJSA-N 50047149 (Racemic) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL25359 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047149&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44275135 103977837 CHEMBL25359 ZINC13826911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764442 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 142 ChEMBL 10.1021/jm00062a025 10.7270/Q2F47PRT 8098771 Foulon, C; Kung, MP; Kung, HF University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748418 COc1ccc2CCC3C(CCCN3Cc3ccccc3)c2c1 InChI=1S/C21H25NO/c1-23-18-11-9-17-10-12-21-19(20(17)14-18)8-5-13-22(21)15-16-6-3-2-4-7-16/h2-4,6-7,9,11,14,19,21H,5,8,10,12-13,15H2,1H3 NSGMNJDNHSTYBY-UHFFFAOYSA-N 50018642 CHEMBL69169::rac-4-Benzyl-9-methoxy-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline D(2) dopamine receptor Rattus norvegicus 5520 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039984 103929734 CHEMBL69169 ZINC26268616 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748419 CN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C12H17NO/c1-13-7-3-5-11(9-13)10-4-2-6-12(14)8-10/h2,4,6,8,11,14H,3,5,7,9H2,1H3/t11-/m0/s1 DKJJTEBJFLYIIS-NSHDSACASA-N 50367446 CHEMBL49617 D(2) dopamine receptor Rattus norvegicus 4120 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937957 160846548 CHEMBL49617 ZINC13651748 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748421 CCN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C13H19NO/c1-2-14-8-4-6-12(10-14)11-5-3-7-13(15)9-11/h3,5,7,9,12,15H,2,4,6,8,10H2,1H3/t12-/m0/s1 GQOCTCQZVMEJSY-LBPRGKRZSA-N 50367447 CHEMBL47750 D(2) dopamine receptor Rattus norvegicus 3490 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937962 160846549 CHEMBL47750 ZINC13651750 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748424 COc1ccc2CCC3C(CCCN3CCc3ccccc3)c2c1 InChI=1S/C22H27NO/c1-24-19-11-9-18-10-12-22-20(21(18)16-19)8-5-14-23(22)15-13-17-6-3-2-4-7-17/h2-4,6-7,9,11,16,20,22H,5,8,10,12-15H2,1H3 VJLOZFYJBHCUSC-UHFFFAOYSA-N 50018658 CHEMBL70186::rac-9-Methoxy-4-phenethyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinoline D(2) dopamine receptor Rattus norvegicus 435 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018658&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039988 103929750 CHEMBL70186 ZINC26272173 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748433 CCCN1CCCC(C1)c1cccc(F)c1 InChI=1S/C14H20FN/c1-2-8-16-9-4-6-13(11-16)12-5-3-7-14(15)10-12/h3,5,7,10,13H,2,4,6,8-9,11H2,1H3 ZEDMIQRQBPLMQU-UHFFFAOYSA-N 50018664 3-(3-Fluoro-phenyl)-1-propyl-piperidine::CHEMBL68916 D(2) dopamine receptor Rattus norvegicus 8055 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018664&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 128974 103929756 CHEMBL68916 ZINC05833838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748447 Oc1cccc(c1)[C@H]1CCCN(CCc2ccccc2)C1 InChI=1S/C19H23NO/c21-19-10-4-8-17(14-19)18-9-5-12-20(15-18)13-11-16-6-2-1-3-7-16/h1-4,6-8,10,14,18,21H,5,9,11-13,15H2/t18-/m0/s1 HGPMWSZMWSQMKY-SFHVURJKSA-N 50367449 CHEMBL68855 D(2) dopamine receptor Rattus norvegicus 1240 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367449&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937981 160846551 CHEMBL68855 ZINC06096175 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748449 Oc1cccc2C3CCCN(CCc4ccccc4)C3CCc12 InChI=1S/C21H25NO/c23-21-10-4-8-17-18-9-5-14-22(20(18)12-11-19(17)21)15-13-16-6-2-1-3-7-16/h1-4,6-8,10,18,20,23H,5,9,11-15H2 BVSDTPWJTLBRCF-UHFFFAOYSA-N 50018661 CHEMBL70929::rac-4-Phenethyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol D(2) dopamine receptor Rattus norvegicus 6 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018661&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039941 103929753 CHEMBL70929 ZINC34213050 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748451 CCCN1CCCC2C1CCc1c(O)cccc21 InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3 ANYSYRVXKLTFPB-UHFFFAOYSA-N 50018650 (R,R)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-l::(R,S)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-l::(S,R)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-l::(S,S)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-l::4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol::CHEMBL68558::rac-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018650&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 137303 103929742 CHEMBL68558 ZINC05833860 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748452 CCCN1CCCC(C1)c1cccc(c1)C(F)(F)F InChI=1S/C15H20F3N/c1-2-8-19-9-4-6-13(11-19)12-5-3-7-14(10-12)15(16,17)18/h3,5,7,10,13H,2,4,6,8-9,11H2,1H3 GBOLYPGBMMGDGB-UHFFFAOYSA-N 50018662 1-Propyl-3-(3-trifluoromethyl-phenyl)-piperidine::CHEMBL67329 D(2) dopamine receptor Rattus norvegicus 786 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018662&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3053803 103929754 CHEMBL67329 ZINC26259876 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748453 Oc1ccc2CCC3NCCCC3c2c1 InChI=1S/C13H17NO/c15-10-5-3-9-4-6-13-11(12(9)8-10)2-1-7-14-13/h3,5,8,11,13-15H,1-2,4,6-7H2 IETCXPRUYLQUEH-UHFFFAOYSA-N 50018652 1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-9-ol::CHEMBL56630::rac-1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 30400 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018652&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039966 103929744 CHEMBL56630 ZINC29558948 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748455 CCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C13H19NO/c1-2-14-8-4-6-12(10-14)11-5-3-7-13(15)9-11/h3,5,7,9,12,15H,2,4,6,8,10H2,1H3/t12-/m1/s1 GQOCTCQZVMEJSY-GFCCVEGCSA-N 50367445 CHEMBL49597 D(2) dopamine receptor Rattus norvegicus 1320 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937964 160846547 CHEMBL49597 ZINC13651751 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748459 Oc1ccc2CCC3C(CCCN3CCc3ccccc3)c2c1 InChI=1S/C21H25NO/c23-18-10-8-17-9-11-21-19(20(17)15-18)7-4-13-22(21)14-12-16-5-2-1-3-6-16/h1-3,5-6,8,10,15,19,21,23H,4,7,9,11-14H2 CEGKVZBKRKDYNI-UHFFFAOYSA-N 50018665 CHEMBL67440::rac-4-Phenethyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 990 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018665&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039990 103929757 CHEMBL67440 ZINC26262967 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748461 Oc1cccc(c1)[C@@H]1CCCN(CCc2ccccc2)C1 InChI=1S/C19H23NO/c21-19-10-4-8-17(14-19)18-9-5-12-20(15-18)13-11-16-6-2-1-3-7-16/h1-4,6-8,10,14,18,21H,5,9,11-13,15H2/t18-/m1/s1 HGPMWSZMWSQMKY-GOSISDBHSA-N 50367448 CHEMBL66208 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367448&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937983 160846550 CHEMBL66208 ZINC06096176 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748464 CCCCN1CCCC2C1CCc1c(O)cccc21 InChI=1S/C17H25NO/c1-2-3-11-18-12-5-7-14-13-6-4-8-17(19)15(13)9-10-16(14)18/h4,6,8,14,16,19H,2-3,5,7,9-12H2,1H3 GUKMJWHYSGRDJJ-UHFFFAOYSA-N 50018666 4-Butyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol::CHEMBL305000::rac-4-Butyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-ol D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018666&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039963 103929758 CHEMBL305000 ZINC26278088 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748465 CN1CCCC2C1CCc1ccc(O)cc21 InChI=1S/C14H19NO/c1-15-8-2-3-12-13-9-11(16)6-4-10(13)5-7-14(12)15/h4,6,9,12,14,16H,2-3,5,7-8H2,1H3 MSOIKWXYXSTUTH-UHFFFAOYSA-N 50018667 4-Methyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol::CHEMBL56617::rac-4-Methyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 265 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018667&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039969 103929759 CHEMBL56617 ZINC29555539 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50748467 CCCN1CCC[C@@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m0/s1 HTSNFXAICLXZMA-ZDUSSCGKSA-N 50010618 (+)-3-(1-Propyl-piperidin-3-yl)-phenol::3-((R)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(-)::CHEMBL7393::cid_202478 D(2) dopamine receptor Rattus norvegicus 1710 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 202478 103923392 CHEMBL7393 ZINC00000393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779509 CC(C)[C@@H](Nc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12)C(O)=O InChI=1S/C27H35N5O3S/c1-19(2)24(27(34)35)29-22-11-5-3-9-20(22)26(33)28-13-7-8-14-31-15-17-32(18-16-31)25-21-10-4-6-12-23(21)36-30-25/h3-6,9-12,19,24,29H,7-8,13-18H2,1-2H3,(H,28,33)(H,34,35)/t24-/m1/s1 GSZHOWDOPPWVOO-XMMPIXPASA-N 50051266 (R)-2-{2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butylcarbamoyl]-phenylamino}-3-methyl-butyric acid; hydrochloride::CHEMBL545143 D(2) dopamine receptor Rattus norvegicus 4.3 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051266&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44271822 103948264 CHEMBL545143 ZINC36187748 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779516 Nc1ccc(Cl)cc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H26ClN5OS/c23-16-7-8-19(24)18(15-16)22(29)25-9-3-4-10-27-11-13-28(14-12-27)21-17-5-1-2-6-20(17)30-26-21/h1-2,5-8,15H,3-4,9-14,24H2,(H,25,29) VMUPGTNVNRQALH-UHFFFAOYSA-N 50051249 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-5-chloro-benzamide; hydrochloride::CHEMBL558192 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10551250 103948247 CHEMBL558192 ZINC13747189 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779518 CC(C)(C)c1ccc(cc1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C26H34N4OS/c1-26(2,3)21-12-10-20(11-13-21)25(31)27-14-6-7-15-29-16-18-30(19-17-29)24-22-8-4-5-9-23(22)32-28-24/h4-5,8-13H,6-7,14-19H2,1-3H3,(H,27,31) YXQGBVQXSRXGCH-UHFFFAOYSA-N 50051248 CHEMBL536566::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4-tert-butyl-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 340 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051248&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10575569 103948246 CHEMBL536566 ZINC13747124 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779519 CCc1cc(Cl)c(OC)c(C(=O)NCCCCN2CCN(CC2)c2nsc3ccccc23)c1OC InChI=1S/C26H33ClN4O3S/c1-4-18-17-20(27)24(34-3)22(23(18)33-2)26(32)28-11-7-8-12-30-13-15-31(16-14-30)25-19-9-5-6-10-21(19)35-29-25/h5-6,9-10,17H,4,7-8,11-16H2,1-3H3,(H,28,32) DJJDVFVEIPWRBN-UHFFFAOYSA-N 50051267 CHEMBL544675::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-chloro-5-ethyl-2,6-dimethoxy-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051267&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10768199 103948265 CHEMBL544675 ZINC13747162 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779522 Cc1cccc(N)c1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H29N5OS/c1-17-7-6-9-19(24)21(17)23(29)25-11-4-5-12-27-13-15-28(16-14-27)22-18-8-2-3-10-20(18)30-26-22/h2-3,6-10H,4-5,11-16,24H2,1H3,(H,25,29) LTXYSPUSSOCRAR-UHFFFAOYSA-N 50051245 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-6-methyl-benzamide; hydrochloride::CHEMBL542057 D(2) dopamine receptor Rattus norvegicus 290 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051245&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10788417 103948243 CHEMBL542057 ZINC13747172 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779523 NNc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H28N6OS/c23-25-19-9-3-1-7-17(19)22(29)24-11-5-6-12-27-13-15-28(16-14-27)21-18-8-2-4-10-20(18)30-26-21/h1-4,7-10,25H,5-6,11-16,23H2,(H,24,29) PVFOAQFPFMILBP-UHFFFAOYSA-N 50051273 CHEMBL554954::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2-hydrazino-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10670032 103948271 CHEMBL554954 ZINC13747145 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779527 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1ccc(cc1)\N=N\c1ccccc1 InChI=1S/C28H30N6OS/c35-28(22-12-14-24(15-13-22)31-30-23-8-2-1-3-9-23)29-16-6-7-17-33-18-20-34(21-19-33)27-25-10-4-5-11-26(25)36-32-27/h1-5,8-15H,6-7,16-21H2,(H,29,35)/b31-30+ SLTFBWXIDUVFSF-NVQSTNCTSA-N 50051278 CHEMBL542309::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4-phenylazo-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10767648 103948276 CHEMBL542309 ZINC13747129 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779535 CN(CCCCN1CCN(CC1)c1nsc2ccccc12)C(=O)c1ccccc1 InChI=1S/C23H28N4OS/c1-25(23(28)19-9-3-2-4-10-19)13-7-8-14-26-15-17-27(18-16-26)22-20-11-5-6-12-21(20)29-24-22/h2-6,9-12H,7-8,13-18H2,1H3 UNFZXGFODICBBR-UHFFFAOYSA-N 50051257 CHEMBL545607::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-N-methyl-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692833 103948255 CHEMBL545607 ZINC13747155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779537 CC(=O)Nc1ccc(cc1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H29N5O2S/c1-18(30)26-20-10-8-19(9-11-20)24(31)25-12-4-5-13-28-14-16-29(17-15-28)23-21-6-2-3-7-22(21)32-27-23/h2-3,6-11H,4-5,12-17H2,1H3,(H,25,31)(H,26,30) UUYZSHGWTYCQDX-UHFFFAOYSA-N 50051271 4-Acetylamino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-benzamide; hydrochloride::CHEMBL552816 D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051271&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10742244 103948269 CHEMBL552816 ZINC13747136 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779543 COc1ccc(N)c(c1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H29N5O2S/c1-30-17-8-9-20(24)19(16-17)23(29)25-10-4-5-11-27-12-14-28(15-13-27)22-18-6-2-3-7-21(18)31-26-22/h2-3,6-9,16H,4-5,10-15,24H2,1H3,(H,25,29) KYWDYLWXAIMECX-UHFFFAOYSA-N 50051270 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-5-methoxy-benzamide; hydrochloride::CHEMBL544674 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051270&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717919 103948268 CHEMBL544674 ZINC13747177 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779545 Nc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H27N5OS/c23-19-9-3-1-7-17(19)22(28)24-11-5-6-12-26-13-15-27(16-14-26)21-18-8-2-4-10-20(18)29-25-21/h1-4,7-10H,5-6,11-16,23H2,(H,24,28) GMDXHLCLNHCEIC-UHFFFAOYSA-N 85048 CHEMBL537481::Glaxo 1192U90 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127912 136351148 CHEMBL537481 ZINC01537573 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779550 COc1ccc(Br)c(OC)c1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H29BrN4O3S/c1-31-19-10-9-18(25)22(32-2)21(19)24(30)26-11-5-6-12-28-13-15-29(16-14-28)23-17-7-3-4-8-20(17)33-27-23/h3-4,7-10H,5-6,11-16H2,1-2H3,(H,26,30) RHAFVVVYTKSXMK-UHFFFAOYSA-N 50051250 CHEMBL545144::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-bromo-2,6-dimethoxy-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10578206 103948248 CHEMBL545144 ZINC36187749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779551 Clc1ccc(cc1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H25ClN4OS/c23-18-9-7-17(8-10-18)22(28)24-11-3-4-12-26-13-15-27(16-14-26)21-19-5-1-2-6-20(19)29-25-21/h1-2,5-10H,3-4,11-16H2,(H,24,28) RUKGNEZVPPFFKX-UHFFFAOYSA-N 50051282 CHEMBL545373::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4-chloro-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 57 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10836319 103948280 CHEMBL545373 ZINC13747118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779554 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 290 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779557 CCOC(=O)Nc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C25H31N5O3S/c1-2-33-25(32)27-21-11-5-3-9-19(21)24(31)26-13-7-8-14-29-15-17-30(18-16-29)23-20-10-4-6-12-22(20)34-28-23/h3-6,9-12H,2,7-8,13-18H2,1H3,(H,26,31)(H,27,32) LOGBZPHGQPXCHJ-UHFFFAOYSA-N 50051251 CHEMBL542058::{2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butylcarbamoyl]-phenyl}-carbamic acid ethyl ester; hydrochloride D(2) dopamine receptor Rattus norvegicus 5.4 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10672419 103948249 CHEMBL542058 ZINC13747149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779558 [N-]=[N+]=Nc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H25N7OS/c23-27-25-19-9-3-1-7-17(19)22(30)24-11-5-6-12-28-13-15-29(16-14-28)21-18-8-2-4-10-20(18)31-26-21/h1-4,7-10H,5-6,11-16H2,(H,24,30) UDKYRFDOLLWBAY-UHFFFAOYSA-N 50051284 2-Azido-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-benzamide; hydrochloride::CHEMBL552889 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051284&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717745 103948282 CHEMBL552889 ZINC13747114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779560 CC(C)(C)OC(=O)Nc1ccc(cc1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C27H35N5O3S/c1-27(2,3)35-26(34)29-21-12-10-20(11-13-21)25(33)28-14-6-7-15-31-16-18-32(19-17-31)24-22-8-4-5-9-23(22)36-30-24/h4-5,8-13H,6-7,14-19H2,1-3H3,(H,28,33)(H,29,34) HNZXNNAOSSPHBX-UHFFFAOYSA-N 50051285 CHEMBL542554::{4-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butylcarbamoyl]-phenyl}-carbamic acid tert-butyl ester; hydrochloride D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051285&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10505854 103948283 CHEMBL542554 ZINC13747133 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779561 Nc1cccc(Cl)c1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H26ClN5OS/c23-17-7-5-8-18(24)20(17)22(29)25-10-3-4-11-27-12-14-28(15-13-27)21-16-6-1-2-9-19(16)30-26-21/h1-2,5-9H,3-4,10-15,24H2,(H,25,29) OYOIWPRKYLJCKE-UHFFFAOYSA-N 50051274 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-6-chloro-benzamide; hydrochloride::CHEMBL545372 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051274&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10527245 103948272 CHEMBL545372 ZINC13747168 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779563 CCc1cc(Cl)c(OC)c(C(=O)NCCCCN2CCN(CC2)c2nsc3ccccc23)c1O InChI=1S/C25H31ClN4O3S/c1-3-17-16-19(26)23(33-2)21(22(17)31)25(32)27-10-6-7-11-29-12-14-30(15-13-29)24-18-8-4-5-9-20(18)34-28-24/h4-5,8-9,16,31H,3,6-7,10-15H2,1-2H3,(H,27,32) QPEHKOOZIPJYAU-UHFFFAOYSA-N 50051269 CHEMBL557182::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-chloro-5-ethyl-6-hydroxy-2-methoxy-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051269&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10601561 103948267 CHEMBL557182 ZINC13747197 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779564 Cc1cccc(C(=O)NCCCCN2CCN(CC2)c2nsc3ccccc23)c1N InChI=1S/C23H29N5OS/c1-17-7-6-9-19(21(17)24)23(29)25-11-4-5-12-27-13-15-28(16-14-27)22-18-8-2-3-10-20(18)30-26-22/h2-3,6-10H,4-5,11-16,24H2,1H3,(H,25,29) AHMRCTCXIVVGBJ-UHFFFAOYSA-N 50051252 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-methyl-benzamide; hydrochloride::CHEMBL544909 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051252&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574309 103948250 CHEMBL544909 ZINC13747166 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779568 Oc1ccc(Br)c(O)c1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H25BrN4O3S/c23-16-7-8-17(28)19(20(16)29)22(30)24-9-3-4-10-26-11-13-27(14-12-26)21-15-5-1-2-6-18(15)31-25-21/h1-2,5-8,28-29H,3-4,9-14H2,(H,24,30) YQHSWEOSWHNZLJ-UHFFFAOYSA-N 50051286 CHEMBL544434::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-bromo-2,6-dihydroxy-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10505718 103948284 CHEMBL544434 ZINC13747160 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779569 Nc1cc(F)ccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H26FN5OS/c23-16-7-8-17(19(24)15-16)22(29)25-9-3-4-10-27-11-13-28(14-12-27)21-18-5-1-2-6-20(18)30-26-21/h1-2,5-8,15H,3-4,9-14,24H2,(H,25,29) MSRZTJMHKRJLST-UHFFFAOYSA-N 50051283 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4-fluoro-benzamide; hydrochloride::CHEMBL544910 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10646147 103948281 CHEMBL544910 ZINC13747180 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779570 COc1cccc(C(=O)NCCCCN2CCN(CC2)c2nsc3ccccc23)c1N InChI=1S/C23H29N5O2S/c1-30-19-9-6-8-18(21(19)24)23(29)25-11-4-5-12-27-13-15-28(16-14-27)22-17-7-2-3-10-20(17)31-26-22/h2-3,6-10H,4-5,11-16,24H2,1H3,(H,25,29) MDAWBIVBCZPWJB-UHFFFAOYSA-N 50051246 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-methoxy-benzamide; hydrochloride::CHEMBL545371 D(2) dopamine receptor Rattus norvegicus 7.8 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051246&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599194 103948244 CHEMBL545371 ZINC13747191 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779572 COc1c(Br)ccc(O)c1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H27BrN4O3S/c1-31-21-17(24)8-9-18(29)20(21)23(30)25-10-4-5-11-27-12-14-28(15-13-27)22-16-6-2-3-7-19(16)32-26-22/h2-3,6-9,29H,4-5,10-15H2,1H3,(H,25,30) BKSCLCCVAGENMQ-UHFFFAOYSA-N 50051287 CHEMBL545609::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-bromo-6-hydroxy-2-methoxy-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10744505 103948285 CHEMBL545609 ZINC13747195 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779575 FC(F)(F)c1ccc(cc1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H25F3N4OS/c24-23(25,26)18-9-7-17(8-10-18)22(31)27-11-3-4-12-29-13-15-30(16-14-29)21-19-5-1-2-6-20(19)32-28-21/h1-2,5-10H,3-4,11-16H2,(H,27,31) JBRMKWSIIOLAAC-UHFFFAOYSA-N 50051272 CHEMBL538972::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4-trifluoromethyl-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051272&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10600133 103948270 CHEMBL538972 ZINC13747122 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779576 Nc1ccc(cc1C(=O)NCCCCN1CCN(CC1)c1n[s+]c2cccc[c-]12)[N+]([O-])=O InChI=1S/C22H26N6O3S/c23-19-8-7-16(28(30)31)15-18(19)22(29)24-9-3-4-10-26-11-13-27(14-12-26)21-17-5-1-2-6-20(17)32-25-21/h1-2,5-8,15H,3-4,9-14,23H2,(H,24,29) XRSGABXRLAWEDU-UHFFFAOYSA-N 50051262 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-5-nitro-benzamide; hydrochloride::CHEMBL537971 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051262&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10766150 103948260 CHEMBL537971 ZINC13747187 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779581 CC(C)[C@H](Nc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12)C(O)=O InChI=1S/C27H35N5O3S/c1-19(2)24(27(34)35)29-22-11-5-3-9-20(22)26(33)28-13-7-8-14-31-15-17-32(18-16-31)25-21-10-4-6-12-23(21)36-30-25/h3-6,9-12,19,24,29H,7-8,13-18H2,1-2H3,(H,28,33)(H,34,35)/t24-/m0/s1 GSZHOWDOPPWVOO-DEOSSOPVSA-N 50051281 (S)-2-{2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butylcarbamoyl]-phenylamino}-3-methyl-butyric acid; hydrochloride::CHEMBL555303 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44271870 103948279 CHEMBL555303 ZINC53084486 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779584 CCc1cc(Cl)c(O)c(C(=O)NCCCCN2CCN(CC2)c2nsc3ccccc23)c1OC InChI=1S/C25H31ClN4O3S/c1-3-17-16-19(26)22(31)21(23(17)33-2)25(32)27-10-6-7-11-29-12-14-30(15-13-29)24-18-8-4-5-9-20(18)34-28-24/h4-5,8-9,16,31H,3,6-7,10-15H2,1-2H3,(H,27,32) VYPOWWQQBJXOGV-UHFFFAOYSA-N 50051264 CHEMBL544206::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-chloro-5-ethyl-2-hydroxy-6-methoxy-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051264&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10553513 103948262 CHEMBL544206 ZINC13747199 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779586 CN(CCCCN1CCN(CC1)c1nsc2ccccc12)C(=O)c1ccccc1N InChI=1S/C23H29N5OS/c1-26(23(29)18-8-2-4-10-20(18)24)12-6-7-13-27-14-16-28(17-15-27)22-19-9-3-5-11-21(19)30-25-22/h2-5,8-11H,6-7,12-17,24H2,1H3 NBDFDYYFHOMBPV-UHFFFAOYSA-N 50051277 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-N-methyl-benzamide; hydrochloride::CHEMBL555644 D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10502415 103948275 CHEMBL555644 ZINC13747157 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779588 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779597 Nc1ccc(F)cc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H26FN5OS/c23-16-7-8-19(24)18(15-16)22(29)25-9-3-4-10-27-11-13-28(14-12-27)21-17-5-1-2-6-20(17)30-26-21/h1-2,5-8,15H,3-4,9-14,24H2,(H,25,29) IZSSCOJRGGDNKM-UHFFFAOYSA-N 50051265 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-5-fluoro-benzamide; hydrochloride::CHEMBL542059 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051265&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10598597 103948263 CHEMBL542059 ZINC13747170 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779598 CC(=O)Nc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C24H29N5O2S/c1-18(30)26-21-10-4-2-8-19(21)24(31)25-12-6-7-13-28-14-16-29(17-15-28)23-20-9-3-5-11-22(20)32-27-23/h2-5,8-11H,6-7,12-17H2,1H3,(H,25,31)(H,26,30) QGXSAIRCYXCNNU-UHFFFAOYSA-N 50051288 2-Acetylamino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-benzamide; hydrochloride::CHEMBL536796 D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051288&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10647253 103948286 CHEMBL536796 ZINC13747147 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779599 Oc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H26N4O2S/c27-19-9-3-1-7-17(19)22(28)23-11-5-6-12-25-13-15-26(16-14-25)21-18-8-2-4-10-20(18)29-24-21/h1-4,7-10,27H,5-6,11-16H2,(H,23,28) AWPMMEUZMRHIOP-UHFFFAOYSA-N 50051253 CHEMBL544908::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2-hydroxy-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 5.8 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051253&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10716503 103948251 CHEMBL544908 ZINC13747139 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779600 COc1ccc(cc1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H28N4O2S/c1-29-19-10-8-18(9-11-19)23(28)24-12-4-5-13-26-14-16-27(17-15-26)22-20-6-2-3-7-21(20)30-25-22/h2-3,6-11H,4-5,12-17H2,1H3,(H,24,28) VXLUVYTVEUVNBU-UHFFFAOYSA-N 50051279 CHEMBL537036::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4-methoxy-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574357 103948277 CHEMBL537036 ZINC13747120 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779601 [O-][N+](=O)c1ccccc1C(=O)NCCCCN1CCN(CC1)c1n[s+]c2cccc[c-]12 InChI=1S/C22H25N5O3S/c28-22(17-7-1-3-9-19(17)27(29)30)23-11-5-6-12-25-13-15-26(16-14-25)21-18-8-2-4-10-20(18)31-24-21/h1-4,7-10H,5-6,11-16H2,(H,23,28) GMFZHSHZWZQXBX-UHFFFAOYSA-N 50051258 CHEMBL553382::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2-nitro-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051258&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717917 103948256 CHEMBL553382 ZINC13747132 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779604 O=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1ccccc1 InChI=1S/C22H26N4OS/c27-22(18-8-2-1-3-9-18)23-12-6-7-13-25-14-16-26(17-15-25)21-19-10-4-5-11-20(19)28-24-21/h1-5,8-11H,6-7,12-17H2,(H,23,27) PNVIFQUVVSDHLW-UHFFFAOYSA-N 50051247 CHEMBL542310::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10834480 103948245 CHEMBL542310 ZINC13747116 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785182 CCN(CC)CCN1CC[C@]2(C)[C@H](C)[C@@H]1Cc1ccc(O)cc21 InChI=1S/C20H32N2O/c1-5-21(6-2)11-12-22-10-9-20(4)15(3)19(22)13-16-7-8-17(23)14-18(16)20/h7-8,14-15,19,23H,5-6,9-13H2,1-4H3/t15-,19+,20-/m1/s1 XEFAZJTWHJDIME-UIAACRFSSA-N 50064190 (2S,6R,11S)-3-(2-Diethylamino-ethyl)-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL39284 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970333f 10.7270/Q2C24X3R 9572883 Ronsisvalle, G; Marrazzo, A; Prezzavento, O; Pasquinucci, L; Vittorio, F; Pittala, V; Pappalardo, MS; Cacciaguerra, S; Spampinato, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064190&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10663237 103959256 CHEMBL39284 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785184 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCN1CCOCC1 InChI=1S/C20H30N2O2/c1-15-19-13-16-3-4-17(23)14-18(16)20(15,2)5-6-22(19)8-7-21-9-11-24-12-10-21/h3-4,14-15,19,23H,5-13H2,1-2H3/t15-,19+,20-/m1/s1 GKIYTUZZUSXSMR-UIAACRFSSA-N 50064188 (2S,6R,11S)-6,11-Dimethyl-3-(2-morpholin-4-yl-ethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL288285 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970333f 10.7270/Q2C24X3R 9572883 Ronsisvalle, G; Marrazzo, A; Prezzavento, O; Pasquinucci, L; Vittorio, F; Pittala, V; Pappalardo, MS; Cacciaguerra, S; Spampinato, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064188 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064188&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10404406 103959254 CHEMBL288285 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785190 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCNC1CCCCC1 InChI=1S/C22H34N2O/c1-16-21-14-17-8-9-19(25)15-20(17)22(16,2)10-12-24(21)13-11-23-18-6-4-3-5-7-18/h8-9,15-16,18,21,23,25H,3-7,10-14H2,1-2H3/t16-,21+,22-/m1/s1 YPBUSZBTDZOKNZ-URZJWIJPSA-N 50064194 (2S,6R,11S)-3-(2-Cyclohexylamino-ethyl)-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL38697 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970333f 10.7270/Q2C24X3R 9572883 Ronsisvalle, G; Marrazzo, A; Prezzavento, O; Pasquinucci, L; Vittorio, F; Pittala, V; Pappalardo, MS; Cacciaguerra, S; Spampinato, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064194 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064194&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10783531 103959260 CHEMBL38697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50768507 CCN(CC)CCOC(=O)C1(CCCC1)c1ccccc1 InChI=1S/C18H27NO2/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3 OFAIGZWCDGNZGT-UHFFFAOYSA-N 73402 1-Phenyl-cyclopentanecarboxylic acid 2-diethylamino-ethyl ester::1-phenyl-1-cyclopentanecarboxylic acid 2-(diethylamino)ethyl ester;hydrochloride::1-phenylcyclopentanecarboxylic acid 2-(diethylamino)ethyl ester;hydrochloride::2-(diethylamino)ethyl 1-phenylcyclopentane-1-carboxylate;hydrochloride::2-(diethylamino)ethyl 1-phenylcyclopentanecarboxylate hydrochloride::CARAMIPHEN::CHEMBL61946::MLS000532799::SMR000140237::cid_67173 D(2) dopamine receptor Rattus norvegicus >500 ChEMBL 10.1021/jm00039a008 10.7270/Q2QZ2BMR 8027978 Hudkins, RL; Mailman, RB; DeHaven-Hudkins, DL Albany Molecular Research, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=73402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=73402&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6472 252650644 CHEMBL61946 ZINC01847743 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50768522 [O-][N+](=O)c1ccc(cc1)C1(CCCC1)C(=O)OCCN1CCC(CC1)c1ccccc1 InChI=1S/C25H30N2O4/c28-24(25(14-4-5-15-25)22-8-10-23(11-9-22)27(29)30)31-19-18-26-16-12-21(13-17-26)20-6-2-1-3-7-20/h1-3,6-11,21H,4-5,12-19H2 DUGKDCSYXCEMBF-UHFFFAOYSA-N 50038707 1-(4-Nitro-phenyl)-cyclopentanecarboxylic acid 2-(4-phenyl-piperidin-1-yl)-ethyl ester; hydrochloride::CHEMBL541284 D(2) dopamine receptor Rattus norvegicus >7000 ChEMBL 10.1021/jm00039a008 10.7270/Q2QZ2BMR 8027978 Hudkins, RL; Mailman, RB; DeHaven-Hudkins, DL Albany Molecular Research, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038707&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 190868 103945981 CHEMBL541284 ZINC13737398 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50768525 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm00039a008 10.7270/Q2QZ2BMR 8027978 Hudkins, RL; Mailman, RB; DeHaven-Hudkins, DL Albany Molecular Research, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50768527 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC=C(C)C InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m1/s1 VOKSWYLNZZRQPF-CCKFTAQKSA-N 50035131 (+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(-)-PENTAZOCINE::(1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-10-azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-trien-4-ol::(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(2R,6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(2S,3R,6S,11S)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(2S,6S,11S)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(6R,11S)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-ethano-benzo[d]azocin-8-ol(+)-pentazocine::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol ((+)-pentazocine)::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol anion::6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol((+)pentazocine)::CHEMBL60542 D(2) dopamine receptor Rattus norvegicus >5000 ChEMBL 10.1021/jm00039a008 10.7270/Q2QZ2BMR 8027978 Hudkins, RL; Mailman, RB; DeHaven-Hudkins, DL Albany Molecular Research, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035131&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GM4 6DK1 12259685 103943179 CHEMBL60542 ZINC02015833 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774211 COc1ccccc1N1CCN(Cc2ccc(CCN3CCCCC3=O)n2C)CC1 InChI=1S/C24H34N4O2/c1-25-20(12-14-28-13-6-5-9-24(28)29)10-11-21(25)19-26-15-17-27(18-16-26)22-7-3-4-8-23(22)30-2/h3-4,7-8,10-11H,5-6,9,12-19H2,1-2H3 PAJXBOSEXAMICQ-UHFFFAOYSA-N 50029294 1-(2-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-yl}-ethyl)-piperidin-2-one; hydrochloride::CHEMBL539292 D(2) dopamine receptor Rattus norvegicus >30 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029294&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10835407 103938365 CHEMBL539292 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774212 COc1ccccc1N1CCN(Cc2ccc(CN3C(=O)c4ccccc4C3=O)o2)CC1 InChI=1S/C25H25N3O4/c1-31-23-9-5-4-8-22(23)27-14-12-26(13-15-27)16-18-10-11-19(32-18)17-28-24(29)20-6-2-3-7-21(20)25(28)30/h2-11H,12-17H2,1H3 FQPYQERAUASZPW-UHFFFAOYSA-N 50029270 2-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-furan-2-ylmethyl}-isoindole-1,3-dione::CHEMBL133765 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029270&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10622574 103938341 CHEMBL133765 ZINC13743852 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774213 COc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)o2)CC1 InChI=1S/C22H29N3O3/c1-27-21-7-3-2-6-20(21)24-14-12-23(13-15-24)16-18-9-10-19(28-18)17-25-11-5-4-8-22(25)26/h2-3,6-7,9-10H,4-5,8,11-17H2,1H3 JXDSOXXEBRBDKD-UHFFFAOYSA-N 50029288 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-furan-2-ylmethyl}-piperidin-2-one;succinate D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029288&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10667681 103938359 ZINC13743849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774215 COc1ccccc1N1CCN(Cc2ccc(CN(C)S(=O)(=O)C(C)C)n2C)CC1 InChI=1S/C22H34N4O3S/c1-18(2)30(27,28)23(3)16-19-10-11-20(24(19)4)17-25-12-14-26(15-13-25)21-8-6-7-9-22(21)29-5/h6-11,18H,12-17H2,1-5H3 NQRLHKAPPFBDJH-UHFFFAOYSA-N 50029279 Propane-2-sulfonic acid {5-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-methyl-amide;succinate D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10765289 103938350 ZINC13743842 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774216 CNC(=O)c1ccc(CN2CCN(CC2)c2ccccc2OC(C)C)n1C InChI=1S/C21H30N4O2/c1-16(2)27-20-8-6-5-7-18(20)25-13-11-24(12-14-25)15-17-9-10-19(23(17)4)21(26)22-3/h5-10,16H,11-15H2,1-4H3,(H,22,26) LBLILDRXQSWWTP-UHFFFAOYSA-N 50029264 5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrole-2-carboxylic acid methylamide;succinate D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029264&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10832974 103938335 ZINC13743846 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774217 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN)c2)CC1 InChI=1S/C21H29N3O/c1-17(2)25-21-9-4-3-8-20(21)24-12-10-23(11-13-24)16-19-7-5-6-18(14-19)15-22/h3-9,14,17H,10-13,15-16,22H2,1-2H3 GUAUPJNJQVBWRS-UHFFFAOYSA-N 50029295 3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzylamine ; succinate D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029295&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10521066 103938366 ZINC13743865 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774218 Cc1ccccc1N1CCN(Cc2cccc(c2)C(O)C2CCCCC2)CC1 InChI=1S/C25H34N2O/c1-20-8-5-6-13-24(20)27-16-14-26(15-17-27)19-21-9-7-12-23(18-21)25(28)22-10-3-2-4-11-22/h5-9,12-13,18,22,25,28H,2-4,10-11,14-17,19H2,1H3 SOUJESDETDCEAS-UHFFFAOYSA-N 50029296 CHEMBL134304::Cyclohexyl-[3-(4-o-tolyl-piperazin-1-ylmethyl)-phenyl]-methanol D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029296&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44355621 103938367 CHEMBL134304 C03491 ZINC27423725 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774220 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(O)c2ccccc2)CC1 InChI=1S/C27H32N2O2/c1-21(2)31-26-14-7-6-13-25(26)29-17-15-28(16-18-29)20-22-9-8-12-24(19-22)27(30)23-10-4-3-5-11-23/h3-14,19,21,27,30H,15-18,20H2,1-2H3 DXKPKHZYFJOYGC-UHFFFAOYSA-N 50029297 CHEMBL135135::{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-phenyl-methanol D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029297&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10788070 103938368 CHEMBL135135 ZINC11689521 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774222 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3C(=O)CC(C)CC3=O)c2)CC1 InChI=1S/C27H35N3O3/c1-20(2)33-25-10-5-4-9-24(25)29-13-11-28(12-14-29)18-22-7-6-8-23(17-22)19-30-26(31)15-21(3)16-27(30)32/h4-10,17,20-21H,11-16,18-19H2,1-3H3 OKLHVQWFAGJSBO-UHFFFAOYSA-N 50029301 1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-4-methyl-piperidine-2,6-dione with succinic acid D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029301&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10837225 103938372 ZINC03804298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774223 CC(C)C(O)c1cccc(CN2CCN(CC2)c2ccccc2C)c1 InChI=1S/C22H30N2O/c1-17(2)22(25)20-9-6-8-19(15-20)16-23-11-13-24(14-12-23)21-10-5-4-7-18(21)3/h4-10,15,17,22,25H,11-14,16H2,1-3H3 PJOGOJLTFFSGPB-UHFFFAOYSA-N 50029303 2-Methyl-1-[3-(4-o-tolyl-piperazin-1-ylmethyl)-phenyl]-propan-1-ol::CHEMBL135107 D(2) dopamine receptor Rattus norvegicus 90 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029303&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44355634 103938374 CHEMBL135107 ZINC27421567 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774231 CC(C)Oc1ccccc1N1CCN(Cc2cccc(Cn3c(O)c[nH]c3=O)c2)CC1 InChI=1S/C24H30N4O3/c1-18(2)31-22-9-4-3-8-21(22)27-12-10-26(11-13-27)16-19-6-5-7-20(14-19)17-28-23(29)15-25-24(28)30/h3-9,14-15,18,29H,10-13,16-17H2,1-2H3,(H,25,30) SXNKBVJLZLQMDV-UHFFFAOYSA-N 50029311 3-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-imidazolidine-2,4-dione::CHEMBL443546 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029311&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54329794 103938382 CHEMBL443546 ZINC00837580 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774234 CC(C)Oc1ccccc1N1CCN(Cc2cccc(Cn3cc(O)[nH]c3=O)c2)CC1 InChI=1S/C24H30N4O3/c1-18(2)31-22-9-4-3-8-21(22)27-12-10-26(11-13-27)15-19-6-5-7-20(14-19)16-28-17-23(29)25-24(28)30/h3-9,14,17-18,29H,10-13,15-16H2,1-2H3,(H,25,30) URGJDNSQMALMNG-UHFFFAOYSA-N 50029314 1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-imidazolidine-2,4-dione::CHEMBL135938 D(2) dopamine receptor Rattus norvegicus 90 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54368184 103938385 CHEMBL135938 ZINC00837582 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774235 CCC(C)(O)c1cccc(CN2CCN(CC2)c2ccccc2C)c1 InChI=1S/C22H30N2O/c1-4-22(3,25)20-10-7-9-19(16-20)17-23-12-14-24(15-13-23)21-11-6-5-8-18(21)2/h5-11,16,25H,4,12-15,17H2,1-3H3 WQPFBCPXUKGSFE-UHFFFAOYSA-N 50029315 2-[3-(4-o-Tolyl-piperazin-1-ylmethyl)-phenyl]-butan-2-ol::CHEMBL135129 D(2) dopamine receptor Rattus norvegicus 198 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029315&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44355635 103938386 CHEMBL135129 ZINC27421576 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774236 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3C(=O)c4ccccc4C3=O)c2)CC1 InChI=1S/C29H31N3O3/c1-21(2)35-27-13-6-5-12-26(27)31-16-14-30(15-17-31)19-22-8-7-9-23(18-22)20-32-28(33)24-10-3-4-11-25(24)29(32)34/h3-13,18,21H,14-17,19-20H2,1-2H3 FNIOXNWZCPVAER-UHFFFAOYSA-N 50029316 2-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-isoindole-1,3-dione with succinic acid D(2) dopamine receptor Rattus norvegicus 57 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029316&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10742958 103938387 ZINC00835564 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774237 CC(C)Oc1ccccc1N1CCN(Cc2cccc(Cc3[nH]c(=O)[nH]c3O)c2)CC1 InChI=1S/C24H30N4O3/c1-17(2)31-22-9-4-3-8-21(22)28-12-10-27(11-13-28)16-19-7-5-6-18(14-19)15-20-23(29)26-24(30)25-20/h3-9,14,17,29H,10-13,15-16H2,1-2H3,(H2,25,26,30) FHSWTTNYLLXVAR-UHFFFAOYSA-N 50029317 5-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-imidazolidine-2,4-dione::CHEMBL135377 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029317&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53799989 103938388 CHEMBL135377 ZINC03807749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774242 CC(C)Oc1ccccc1N1CCN(Cc2ccccc2CN2CCCCC2=O)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-12-6-5-11-24(25)28-17-15-27(16-18-28)19-22-9-3-4-10-23(22)20-29-14-8-7-13-26(29)30/h3-6,9-12,21H,7-8,13-20H2,1-2H3 BKOZXYDJNCUNBD-UHFFFAOYSA-N 50029319 1-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-piperidin-2-one::CHEMBL10105 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10387475 103938390 CHEMBL10105 ZINC52956220 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774244 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNc3cc(=O)n(C)c(=O)n3C)c2)CC1 InChI=1S/C27H35N5O3/c1-20(2)35-24-11-6-5-10-23(24)32-14-12-31(13-15-32)19-22-9-7-8-21(16-22)18-28-25-17-26(33)30(4)27(34)29(25)3/h5-11,16-17,20,28H,12-15,18-19H2,1-4H3 HOSHLJXJQNFOCY-UHFFFAOYSA-N 50029323 6-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzylamino}-1,3-dimethyl-1H-pyrimidine-2,4-dione with succinic acid D(2) dopamine receptor Rattus norvegicus 65 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10050730 103938394 ZINC13743870 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774245 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNC(C)=O)c2)CC1 InChI=1S/C23H31N3O2/c1-18(2)28-23-10-5-4-9-22(23)26-13-11-25(12-14-26)17-21-8-6-7-20(15-21)16-24-19(3)27/h4-10,15,18H,11-14,16-17H2,1-3H3,(H,24,27) CLXIPSSIONHXBO-UHFFFAOYSA-N 50029302 N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-acetamide with succinic acid D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029302&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10833723 103938373 ZINC13743866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774246 CC(O)c1ccccc1CN1CCN(CC1)c1ccccc1C InChI=1S/C20H26N2O/c1-16-7-3-6-10-20(16)22-13-11-21(12-14-22)15-18-8-4-5-9-19(18)17(2)23/h3-10,17,23H,11-15H2,1-2H3 HOURADXBMCGECC-UHFFFAOYSA-N 50029313 1-[2-(4-o-Tolyl-piperazin-1-ylmethyl)-phenyl]-ethanol::CHEMBL134951 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029313&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44356018 103938384 CHEMBL134951 ZINC27422874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774249 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNC(=O)c3ccccc3)c2)CC1 InChI=1S/C28H33N3O2/c1-22(2)33-27-14-7-6-13-26(27)31-17-15-30(16-18-31)21-24-10-8-9-23(19-24)20-29-28(32)25-11-4-3-5-12-25/h3-14,19,22H,15-18,20-21H2,1-2H3,(H,29,32) LLHWJYJDXPFFRH-UHFFFAOYSA-N 50029310 N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-benzamide with succinic acid D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029310&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599376 103938381 ZINC13743867 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774252 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)cc2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-8-4-3-7-24(25)28-17-15-27(16-18-28)19-22-10-12-23(13-11-22)20-29-14-6-5-9-26(29)30/h3-4,7-8,10-13,21H,5-6,9,14-20H2,1-2H3 AQMSXOSMVXZSPU-UHFFFAOYSA-N 50029306 1-{4-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-piperidin-2-one::CHEMBL275045 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029306&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742940 103938377 CHEMBL275045 ZINC00835560 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774254 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNc3ccc(F)cc3)c2)CC1 InChI=1S/C27H32FN3O/c1-21(2)32-27-9-4-3-8-26(27)31-16-14-30(15-17-31)20-23-7-5-6-22(18-23)19-29-25-12-10-24(28)11-13-25/h3-13,18,21,29H,14-17,19-20H2,1-2H3 XDBNRZXPEASSBJ-UHFFFAOYSA-N 50029325 (4-Fluoro-phenyl)-{3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-amine::CHEMBL135479 D(2) dopamine receptor Rattus norvegicus 117 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10646443 103938396 CHEMBL135479 ZINC13743871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774256 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-12-5-4-11-24(25)28-17-15-27(16-18-28)20-22-9-8-10-23(19-22)26(30)29-13-6-3-7-14-29/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3 ZKZFPRUSWCYSGT-UHFFFAOYSA-N 50029257 (3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)phenyl)(piperidin-1-yl)methanone::CHEMBL10085::RWJ-377796::mazapertine::{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60820 103938328 CHEMBL10085 ZINC52956332 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774258 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3CCCCC3=O)c2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-11-4-3-10-24(25)28-16-14-27(15-17-28)19-22-8-7-9-23(18-22)20-29-13-6-5-12-26(29)30/h3-4,7-11,18,21H,5-6,12-17,19-20H2,1-2H3 RTJRXNDVJCWGSK-UHFFFAOYSA-N 50029300 1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-piperidin-2-one::CHEMBL416703 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029300&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9802305 103938371 CHEMBL416703 ZINC00598896 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774259 Cc1ccccc1N1CCN(Cc2ccc(cc2)C(O)c2ccccc2)CC1 InChI=1S/C25H28N2O/c1-20-7-5-6-10-24(20)27-17-15-26(16-18-27)19-21-11-13-23(14-12-21)25(28)22-8-3-2-4-9-22/h2-14,25,28H,15-19H2,1H3 WAAOQMDEBBISAN-UHFFFAOYSA-N 50029327 Phenyl-[4-(4-o-tolyl-piperazin-1-ylmethyl)-phenyl]-methanol with succinic acid D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44356028 103938398 ZINC27418240 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774260 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN(C)C(C)=O)c2)CC1 InChI=1S/C24H33N3O2/c1-19(2)29-24-11-6-5-10-23(24)27-14-12-26(13-15-27)18-22-9-7-8-21(16-22)17-25(4)20(3)28/h5-11,16,19H,12-15,17-18H2,1-4H3 WMKHOOVULRFAAX-UHFFFAOYSA-N 50029305 N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-N-methyl-acetamide with 1.5M of succinic acid D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029305&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10524745 103938376 ZINC13743869 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774262 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3CCCCC3)c2)CC1 InChI=1S/C26H37N3O/c1-22(2)30-26-12-5-4-11-25(26)29-17-15-28(16-18-29)21-24-10-8-9-23(19-24)20-27-13-6-3-7-14-27/h4-5,8-12,19,22H,3,6-7,13-18,20-21H2,1-2H3 IOOQIYLBXKDKDD-UHFFFAOYSA-N 50029298 1-(2-Isopropoxy-phenyl)-4-(3-piperidin-1-ylmethyl-benzyl)-piperazine::CHEMBL422989 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029298&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10787575 103938369 CHEMBL422989 ZINC13743872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774266 Cc1ccccc1N1CCN(Cc2ccccc2C(O)c2ccccc2)CC1 InChI=1S/C25H28N2O/c1-20-9-5-8-14-24(20)27-17-15-26(16-18-27)19-22-12-6-7-13-23(22)25(28)21-10-3-2-4-11-21/h2-14,25,28H,15-19H2,1H3 VAYSMURKORGEQD-UHFFFAOYSA-N 50029320 CHEMBL135047::Phenyl-[2-(4-o-tolyl-piperazin-1-ylmethyl)-phenyl]-methanol D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44355800 103938391 CHEMBL135047 ZINC27422916 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774271 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3C(=O)CCCC3=O)c2)CC1 InChI=1S/C26H33N3O3/c1-20(2)32-24-10-4-3-9-23(24)28-15-13-27(14-16-28)18-21-7-5-8-22(17-21)19-29-25(30)11-6-12-26(29)31/h3-5,7-10,17,20H,6,11-16,18-19H2,1-2H3 ANXBMRVETYAEAT-UHFFFAOYSA-N 50029309 1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-piperidine-2,6-dione with succinic acid D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029309&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10622766 103938380 ZINC03804270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774273 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3C(=O)CC4(CCCC4)CC3=O)c2)CC1 InChI=1S/C30H39N3O3/c1-23(2)36-27-11-4-3-10-26(27)32-16-14-31(15-17-32)21-24-8-7-9-25(18-24)22-33-28(34)19-30(20-29(33)35)12-5-6-13-30/h3-4,7-11,18,23H,5-6,12-17,19-22H2,1-2H3 LRZBNYMVRJJJKU-UHFFFAOYSA-N 50029326 8-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL423712 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10719846 103938397 CHEMBL423712 ZINC01538978 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774275 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777820 COc1ccccc1N1CCN(CCCCN2C(=O)C(C)(C)SC2(C)C)CC1 InChI=1S/C22H35N3O2S/c1-21(2)20(26)25(22(3,4)28-21)13-9-8-12-23-14-16-24(17-15-23)18-10-6-7-11-19(18)27-5/h6-7,10-11H,8-9,12-17H2,1-5H3 NCRXJBDPIYXLQR-UHFFFAOYSA-N 50053734 3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-2,2,5,5-tetramethyl-thiazolidin-4-one::CHEMBL130906 D(2) dopamine receptor Rattus norvegicus 304 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053734&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10525345 103950413 CHEMBL130906 ZINC13759346 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777822 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 37 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777827 CC1(C)SCN(CCCCN2CCN(CC2)c2csc3cc(F)ccc23)C1=O InChI=1S/C21H28FN3OS2/c1-21(2)20(26)25(15-28-21)8-4-3-7-23-9-11-24(12-10-23)18-14-27-19-13-16(22)5-6-17(18)19/h5-6,13-14H,3-4,7-12,15H2,1-2H3 RXOKXSSCLCWBFA-UHFFFAOYSA-N 50053708 3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-5,5-dimethyl-thiazolidin-4-one::CHEMBL130388 D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053708&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10812139 103950387 CHEMBL130388 ZINC13759439 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777836 O=C1N(CCCCN2CCN(CC2)c2csc3ccccc23)CSC11CCCCC1 InChI=1S/C24H33N3OS2/c28-23-24(10-4-1-5-11-24)30-19-27(23)13-7-6-12-25-14-16-26(17-15-25)21-18-29-22-9-3-2-8-20(21)22/h2-3,8-9,18H,1,4-7,10-17,19H2 BQVJCBCVOOWLFV-UHFFFAOYSA-N 50053730 3-[4-(4-Benzo[b]thiophen-3-yl-piperazin-1-yl)-butyl]-1-thia-3-aza-spiro[4.5]decan-4-one::CHEMBL131364 D(2) dopamine receptor Rattus norvegicus 218 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053730&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10623136 103950409 CHEMBL131364 ZINC13759434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777837 Cc1cccc(c1)N1CCN(CCCCN2C(=O)CSC2(C)C)CC1 InChI=1S/C20H31N3OS/c1-17-7-6-8-18(15-17)22-13-11-21(12-14-22)9-4-5-10-23-19(24)16-25-20(23,2)3/h6-8,15H,4-5,9-14,16H2,1-3H3 HQOFCIQVUAGMFI-UHFFFAOYSA-N 50053744 2,2-Dimethyl-3-[4-(4-m-tolyl-piperazin-1-yl)-butyl]-thiazolidin-4-one::CHEMBL434619 D(2) dopamine receptor Rattus norvegicus 3750 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053744&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594773 103950423 CHEMBL434619 ZINC13759355 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777839 COc1ccccc1N1CCN(CCCCN2CSC(C)(C)C2=O)CC1 InChI=1S/C20H31N3O2S/c1-20(2)19(24)23(16-26-20)11-7-6-10-21-12-14-22(15-13-21)17-8-4-5-9-18(17)25-3/h4-5,8-9H,6-7,10-16H2,1-3H3 VDVCCROWWDIMIS-UHFFFAOYSA-N 50053741 3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-5,5-dimethyl-thiazolidin-4-one::CHEMBL338946 D(2) dopamine receptor Rattus norvegicus 548 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053741&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10595767 103950420 CHEMBL338946 ZINC13759345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777843 CC1(C)SCN(CCCCN2CCN(CC2)c2cn(-c3ccccc3)c3ccccc23)C1=O InChI=1S/C27H34N4OS/c1-27(2)26(32)30(21-33-27)15-9-8-14-28-16-18-29(19-17-28)25-20-31(22-10-4-3-5-11-22)24-13-7-6-12-23(24)25/h3-7,10-13,20H,8-9,14-19,21H2,1-2H3 SGVMQOUZKGKJHX-UHFFFAOYSA-N 50053740 5,5-Dimethyl-3-{4-[4-(1-phenyl-1H-indol-3-yl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL132333 D(2) dopamine receptor Rattus norvegicus 191 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053740&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10695381 103950419 CHEMBL132333 ZINC13759407 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777847 CC1SC(C)(C)C(=O)N1CCCCN1CCN(CC1)c1nsc2cc(Cl)ccc12 InChI=1S/C21H29ClN4OS2/c1-15-26(20(27)21(2,3)28-15)9-5-4-8-24-10-12-25(13-11-24)19-17-7-6-16(22)14-18(17)29-23-19/h6-7,14-15H,4-5,8-13H2,1-3H3 JLTMLNZUNUBPBT-UHFFFAOYSA-N 50053746 3-{4-[4-(6-Chloro-benzo[d]isothiazol-3-yl)-piperazin-1-yl]-butyl}-2,5,5-trimethyl-thiazolidin-4-one::CHEMBL133671 D(2) dopamine receptor Rattus norvegicus 286 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053746&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10551622 103950425 CHEMBL133671 ZINC13759384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777851 CC1SC(C)(C)C(=O)N1CCCCN1CCN(CC1)c1csc2cc(F)ccc12 InChI=1S/C22H30FN3OS2/c1-16-26(21(27)22(2,3)29-16)9-5-4-8-24-10-12-25(13-11-24)19-15-28-20-14-17(23)6-7-18(19)20/h6-7,14-16H,4-5,8-13H2,1-3H3 IWOQWCKSTOAOMQ-UHFFFAOYSA-N 50002107 3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-2,5,5-trimethyl-thiazolidin-4-one::CHEMBL89934 D(2) dopamine receptor Rattus norvegicus 1210 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131396 103916416 CHEMBL89934 ZINC03793084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777852 CC1(C)SCN(CCCCN2CCN(CC2)c2cccc(c2)C(F)(F)F)C1=O InChI=1S/C20H28F3N3OS/c1-19(2)18(27)26(15-28-19)9-4-3-8-24-10-12-25(13-11-24)17-7-5-6-16(14-17)20(21,22)23/h5-7,14H,3-4,8-13,15H2,1-2H3 QSNJCJGBMAHIQV-UHFFFAOYSA-N 50053736 5,5-Dimethyl-3-{4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL134027 D(2) dopamine receptor Rattus norvegicus 1640 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053736&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10597953 103950415 CHEMBL134027 ZINC13759352 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777854 COc1ccccc1N1CCN(CCCCN2C(=O)CSC2(C)C)CC1 InChI=1S/C20H31N3O2S/c1-20(2)23(19(24)16-26-20)11-7-6-10-21-12-14-22(15-13-21)17-8-4-5-9-18(17)25-3/h4-5,8-9H,6-7,10-16H2,1-3H3 DBCSZXGUOIJTRJ-UHFFFAOYSA-N 50053745 3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-2,2-dimethyl-thiazolidin-4-one::CHEMBL132500 D(2) dopamine receptor Rattus norvegicus 514 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053745&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10571658 103950424 CHEMBL132500 ZINC13759338 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777858 CC1(C)SCC(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C20H28N4OS2/c1-20(2)24(18(25)15-26-20)10-6-5-9-22-11-13-23(14-12-22)19-16-7-3-4-8-17(16)27-21-19/h3-4,7-8H,5-6,9-15H2,1-2H3 MRZUWBCILLYOGT-UHFFFAOYSA-N 50053738 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2,2-dimethyl-thiazolidin-4-one::CHEMBL130070 D(2) dopamine receptor Rattus norvegicus 193 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053738&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692629 103950417 CHEMBL130070 ZINC13759370 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777861 CC1SC(C)(C)C(=O)N1CCCCN1CCN(CC1)c1csc2cc(Cl)ccc12 InChI=1S/C22H30ClN3OS2/c1-16-26(21(27)22(2,3)29-16)9-5-4-8-24-10-12-25(13-11-24)19-15-28-20-14-17(23)6-7-18(19)20/h6-7,14-16H,4-5,8-13H2,1-3H3 NHIYPLSPTIMDLJ-UHFFFAOYSA-N 50053743 3-{4-[4-(6-Chloro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-2,5,5-trimethyl-thiazolidin-4-one::CHEMBL130069 D(2) dopamine receptor Rattus norvegicus 4730 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053743&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10837325 103950422 CHEMBL130069 ZINC13759443 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777869 CC1SCN(CCCCN2CCN(CC2)c2nsc3ccccc23)C1=O InChI=1S/C19H26N4OS2/c1-15-19(24)23(14-25-15)9-5-4-8-21-10-12-22(13-11-21)18-16-6-2-3-7-17(16)26-20-18/h2-3,6-7,15H,4-5,8-14H2,1H3 QMGPSYFJSYOZRC-UHFFFAOYSA-N 50053748 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-5-methyl-thiazolidin-4-one::CHEMBL335554 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053748&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10739172 103950427 CHEMBL335554 ZINC13759375 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777877 CC1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1csc2cc(Cl)ccc12 InChI=1S/C24H32ClN3OS2/c1-18-28(23(29)24(31-18)8-2-3-9-24)11-5-4-10-26-12-14-27(15-13-26)21-17-30-22-16-19(25)6-7-20(21)22/h6-7,16-18H,2-5,8-15H2,1H3 IQFDCWASJWOOSB-UHFFFAOYSA-N 50053732 3-{4-[4-(6-Chloro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-2-methyl-1-thia-3-aza-spiro[4.4]nonan-4-one::CHEMBL131583 D(2) dopamine receptor Rattus norvegicus 611 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053732&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10838359 103950411 CHEMBL131583 ZINC13759433 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777879 COc1ccccc1N1CCN(CCCCN2CSC3(CCCC3)C2=O)CC1 InChI=1S/C22H33N3O2S/c1-27-20-9-3-2-8-19(20)24-16-14-23(15-17-24)12-6-7-13-25-18-28-22(21(25)26)10-4-5-11-22/h2-3,8-9H,4-7,10-18H2,1H3 LFEXUUCTMMYBRV-UHFFFAOYSA-N 50053704 3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonan-4-one::CHEMBL131261 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053704&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692544 103950383 CHEMBL131261 ZINC12356263 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777888 CC1SC(C)(C)C(=O)N1CCCCN1CCN(CC1)c1cn(-c2ccccc2)c2ccccc12 InChI=1S/C28H36N4OS/c1-22-31(27(33)28(2,3)34-22)16-10-9-15-29-17-19-30(20-18-29)26-21-32(23-11-5-4-6-12-23)25-14-8-7-13-24(25)26/h4-8,11-14,21-22H,9-10,15-20H2,1-3H3 KQVBGTRXBYOVJC-UHFFFAOYSA-N 50053737 2,5,5-Trimethyl-3-{4-[4-(1-phenyl-1H-indol-3-yl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL334824 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10528598 103950416 CHEMBL334824 ZINC13759413 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777890 O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)CSC11CCCCC1 InChI=1S/C23H32N4OS2/c28-22-23(10-4-1-5-11-23)29-18-27(22)13-7-6-12-25-14-16-26(17-15-25)21-19-8-2-3-9-20(19)30-24-21/h2-3,8-9H,1,4-7,10-18H2 FDCGBFBTTMQKRK-UHFFFAOYSA-N 50053700 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-1-thia-3-aza-spiro[4.5]decan-4-one::CHEMBL131765 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053700&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10646968 103950379 CHEMBL131765 ZINC13759403 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777891 CC1(C)SC(C)(C)C(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H32N4OS2/c1-21(2)20(27)26(22(3,4)29-21)12-8-7-11-24-13-15-25(16-14-24)19-17-9-5-6-10-18(17)28-23-19/h5-6,9-10H,7-8,11-16H2,1-4H3 LOXKOPAIKBYSPS-UHFFFAOYSA-N 50053742 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2,2,5,5-tetramethyl-thiazolidin-4-one::CHEMBL132736 D(2) dopamine receptor Rattus norvegicus 201 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053742&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10550711 103950421 CHEMBL132736 ZINC13759386 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777893 CC(C)(O)C1SCN(CCCCN2CCN(CC2)c2nsc3ccccc23)C1=O InChI=1S/C21H30N4O2S2/c1-21(2,27)18-20(26)25(15-28-18)10-6-5-9-23-11-13-24(14-12-23)19-16-7-3-4-8-17(16)29-22-19/h3-4,7-8,18,27H,5-6,9-15H2,1-2H3 XKVRLBCGIKZDIN-UHFFFAOYSA-N 50053689 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-5-(1-hydroxy-1-methyl-ethyl)-thiazolidin-4-one::CHEMBL339926 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053689&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717711 103950368 CHEMBL339926 ZINC13759394 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777895 CSc1cccc(c1)N1CCN(CCCCN2C(=O)CSC2(C)C)CC1 InChI=1S/C20H31N3OS2/c1-20(2)23(19(24)16-26-20)10-5-4-9-21-11-13-22(14-12-21)17-7-6-8-18(15-17)25-3/h6-8,15H,4-5,9-14,16H2,1-3H3 PGGVCCGESXXUMZ-UHFFFAOYSA-N 50053731 2,2-Dimethyl-3-{4-[4-(3-methylsulfanyl-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL131307 D(2) dopamine receptor Rattus norvegicus 2430 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053731&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10834424 103950410 CHEMBL131307 ZINC13759349 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777896 O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)CSC11CCCC1 InChI=1S/C22H30N4OS2/c27-21-22(9-3-4-10-22)28-17-26(21)12-6-5-11-24-13-15-25(16-14-24)20-18-7-1-2-8-19(18)29-23-20/h1-2,7-8H,3-6,9-17H2 OHTLSULMMUNZKQ-UHFFFAOYSA-N 50053694 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-1-thia-3-aza-spiro[4.4]nonan-4-one::CHEMBL337467 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053694&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10502774 103950373 CHEMBL337467 ZINC12356320 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777898 O=C1N(CCCCN2CCN(CC2)c2cn(-c3ccccc3)c3ccccc23)CSC11CCCCC1 InChI=1S/C30H38N4OS/c35-29-30(15-7-2-8-16-30)36-24-33(29)18-10-9-17-31-19-21-32(22-20-31)28-23-34(25-11-3-1-4-12-25)27-14-6-5-13-26(27)28/h1,3-6,11-14,23H,2,7-10,15-22,24H2 RUKPUHCCONQDGO-UHFFFAOYSA-N 50053747 3-{4-[4-(1-Phenyl-1H-indol-3-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.5]decan-4-one::CHEMBL131130 D(2) dopamine receptor Rattus norvegicus 467 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053747&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10601553 103950426 CHEMBL131130 ZINC13759424 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777901 Cc1cccc(c1)N1CCN(CCCCN2CSC(C)(C)C2=O)CC1 InChI=1S/C20H31N3OS/c1-17-7-6-8-18(15-17)22-13-11-21(12-14-22)9-4-5-10-23-16-25-20(2,3)19(23)24/h6-8,15H,4-5,9-14,16H2,1-3H3 SKMMUQAPKODBNV-UHFFFAOYSA-N 50053749 5,5-Dimethyl-3-[4-(4-m-tolyl-piperazin-1-yl)-butyl]-thiazolidin-4-one::CHEMBL424266 D(2) dopamine receptor Rattus norvegicus 2640 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053749&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10642355 103950428 CHEMBL424266 ZINC13759356 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777905 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 1610 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777913 Cc1ccccc1N1CCN(CCCCN2CSC(C)(C)C2=O)CC1 InChI=1S/C20H31N3OS/c1-17-8-4-5-9-18(17)22-14-12-21(13-15-22)10-6-7-11-23-16-25-20(2,3)19(23)24/h4-5,8-9H,6-7,10-16H2,1-3H3 XTVSAOCUGHTFMT-UHFFFAOYSA-N 50053733 5,5-Dimethyl-3-[4-(4-o-tolyl-piperazin-1-yl)-butyl]-thiazolidin-4-one::CHEMBL130036 D(2) dopamine receptor Rattus norvegicus 1770 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053733&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10666322 103950412 CHEMBL130036 ZINC13759354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779606 COc1ccc(Br)c(O)c1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H27BrN4O3S/c1-31-18-9-8-17(24)21(29)20(18)23(30)25-10-4-5-11-27-12-14-28(15-13-27)22-16-6-2-3-7-19(16)32-26-22/h2-3,6-9,29H,4-5,10-15H2,1H3,(H,25,30) INSDLPNRRROKEU-UHFFFAOYSA-N 50051280 CHEMBL544436::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-bromo-2-hydroxy-6-methoxy-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 0.62 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10768266 103948278 CHEMBL544436 ZINC13747193 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785424 O=C(N1CCCCC1)c1cccc(CN2CCN(CC2)c2ccccc2)c1 InChI=1S/C23H29N3O/c27-23(26-12-5-2-6-13-26)21-9-7-8-20(18-21)19-24-14-16-25(17-15-24)22-10-3-1-4-11-22/h1,3-4,7-11,18H,2,5-6,12-17,19H2 DPVKBVHXDMDPTH-UHFFFAOYSA-N 50064527 CHEMBL417402::[3-(4-Phenyl-piperazin-1-ylmethyl)-phenyl]-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064527&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10737450 103959544 CHEMBL417402 ZINC13779638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785426 CCN1CCCC1CNC(=O)c1cccc(CN2CCN(CC2)c2ccccc2OC(C)C)c1 InChI=1S/C28H40N4O2/c1-4-31-14-8-11-25(31)20-29-28(33)24-10-7-9-23(19-24)21-30-15-17-32(18-16-30)26-12-5-6-13-27(26)34-22(2)3/h5-7,9-10,12-13,19,22,25H,4,8,11,14-18,20-21H2,1-3H3,(H,29,33) GSFRIQFLKZOXIJ-UHFFFAOYSA-N 50064531 CHEMBL64226::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzamide D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10528125 103959548 CHEMBL64226 ZINC13779662 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785427 O=C(N1CCCCC1)c1cccc(CN2CCN(CC2)c2ccccc2C#N)c1 InChI=1S/C24H28N4O/c25-18-22-8-2-3-10-23(22)27-15-13-26(14-16-27)19-20-7-6-9-21(17-20)24(29)28-11-4-1-5-12-28/h2-3,6-10,17H,1,4-5,11-16,19H2 FWRBAMFNRUJMOK-UHFFFAOYSA-N 50064533 2-{4-[3-(Piperidine-1-carbonyl)-benzyl]-piperazin-1-yl}-benzonitrile::CHEMBL62024 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064533&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10834161 103959550 CHEMBL62024 ZINC13779644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785432 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)NC2CCCCC2)CC1 InChI=1S/C27H37N3O2/c1-21(2)32-26-14-7-6-13-25(26)30-17-15-29(16-18-30)20-22-9-8-10-23(19-22)27(31)28-24-11-4-3-5-12-24/h6-10,13-14,19,21,24H,3-5,11-12,15-18,20H2,1-2H3,(H,28,31) QFEOODXDJUNLCP-UHFFFAOYSA-N 50064538 CHEMBL60411::N-Cyclohexyl-3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzamide D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064538&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10550867 103959555 CHEMBL60411 ZINC13779653 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785434 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCC2)CC1 InChI=1S/C24H31N3O2/c1-19(2)29-23-10-4-3-9-22(23)26-15-13-25(14-16-26)18-20-7-5-8-21(17-20)24(28)27-11-6-12-27/h3-5,7-10,17,19H,6,11-16,18H2,1-2H3 JTHHJUAQTPJDQQ-UHFFFAOYSA-N 50064541 Azetidin-1-yl-{3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL291846 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064541&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10548617 103959558 CHEMBL291846 ZINC12356322 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785437 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.37 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785438 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N(C)C(C)=O)CC1 InChI=1S/C24H31N3O3/c1-18(2)30-23-11-6-5-10-22(23)27-14-12-26(13-15-27)17-20-8-7-9-21(16-20)24(29)25(4)19(3)28/h5-11,16,18H,12-15,17H2,1-4H3 RWVQUVBBIKOANZ-UHFFFAOYSA-N 50064535 CHEMBL61963::N-Acetyl-3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-N-methyl-benzamide D(2) dopamine receptor Rattus norvegicus 158 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064535&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10573575 103959552 CHEMBL61963 ZINC13779665 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785439 O=C(N1CCCCC1)c1cccc(CN2CCNCC2)c1 InChI=1S/C17H25N3O/c21-17(20-9-2-1-3-10-20)16-6-4-5-15(13-16)14-19-11-7-18-8-12-19/h4-6,13,18H,1-3,7-12,14H2 WVZUJLFJIDXGIN-UHFFFAOYSA-N 50064543 (3-Piperazin-1-ylmethyl-phenyl)-piperidin-1-yl-methanone::CHEMBL60313 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10755739 103959560 CHEMBL60313 ZINC22938978 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785443 Fc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C23H28FN3O/c24-21-9-2-3-10-22(21)26-15-13-25(14-16-26)18-19-7-6-8-20(17-19)23(28)27-11-4-1-5-12-27/h2-3,6-10,17H,1,4-5,11-16,18H2 GJIZTQCUGLNCEE-UHFFFAOYSA-N 50064546 CHEMBL64210::{3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 263 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064546&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10762417 103959563 CHEMBL64210 ZINC13779642 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785444 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCOCC2)CC1 InChI=1S/C25H33N3O3/c1-20(2)31-24-9-4-3-8-23(24)27-12-10-26(11-13-27)19-21-6-5-7-22(18-21)25(29)28-14-16-30-17-15-28/h3-9,18,20H,10-17,19H2,1-2H3 SOFGPUJNPHENOJ-UHFFFAOYSA-N 50064549 CHEMBL304435::{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-morpholin-4-yl-methanone D(2) dopamine receptor Rattus norvegicus 95 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10598387 103959566 CHEMBL304435 ZINC13779655 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785446 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)Nc2ccc(F)cc2)CC1 InChI=1S/C27H30FN3O2/c1-20(2)33-26-9-4-3-8-25(26)31-16-14-30(15-17-31)19-21-6-5-7-22(18-21)27(32)29-24-12-10-23(28)11-13-24/h3-13,18,20H,14-17,19H2,1-2H3,(H,29,32) OMZXMEGRZKDGGH-UHFFFAOYSA-N 50064545 CHEMBL61926::N-(4-Fluoro-phenyl)-3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzamide D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10694728 103959562 CHEMBL61926 ZINC13779663 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785447 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C25H36N4O2/c1-20(2)31-24-9-5-4-8-23(24)28-16-14-27(15-17-28)18-21-11-12-22(26(21)3)19-29-13-7-6-10-25(29)30/h4-5,8-9,11-12,20H,6-7,10,13-19H2,1-3H3 BLFPEKXTSDYQOQ-UHFFFAOYSA-N 50001869 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL428175::RWJ-25730 D(2) dopamine receptor Rattus norvegicus 0.80 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9910257 103916236 CHEMBL428175 ZINC53255684 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785449 Clc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C23H28ClN3O/c24-21-9-2-3-10-22(21)26-15-13-25(14-16-26)18-19-7-6-8-20(17-19)23(28)27-11-4-1-5-12-27/h2-3,6-10,17H,1,4-5,11-16,18H2 UFYHYCWQQXNJFF-UHFFFAOYSA-N 50064550 CHEMBL294129::{3-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 77 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064550&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10668526 103959567 CHEMBL294129 ZINC13779643 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785452 CC(C)Oc1ccccc1N1CCN(CCCCc2ccc(cc2)C(=O)N2CCCCC2)CC1 InChI=1S/C29H41N3O2/c1-24(2)34-28-12-5-4-11-27(28)31-22-20-30(21-23-31)17-9-6-10-25-13-15-26(16-14-25)29(33)32-18-7-3-8-19-32/h4-5,11-16,24H,3,6-10,17-23H2,1-2H3 WBISYROOPMTIBU-UHFFFAOYSA-N 50064554 (4-{4-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-butyl}-phenyl)-piperidin-1-yl-methanone::CHEMBL61975 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064554&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10813959 103959571 CHEMBL61975 ZINC13779670 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785453 COc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCCC2)CC1 InChI=1S/C25H33N3O2/c1-30-24-12-5-4-11-23(24)27-17-15-26(16-18-27)20-21-9-8-10-22(19-21)25(29)28-13-6-2-3-7-14-28/h4-5,8-12,19H,2-3,6-7,13-18,20H2,1H3 KLAJXRZDLXCVHZ-UHFFFAOYSA-N 50064529 Azepan-1-yl-{3-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL64274 D(2) dopamine receptor Rattus norvegicus 201 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064529&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811379 103959546 CHEMBL64274 ZINC12356358 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785456 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-12-5-4-11-24(25)28-17-15-27(16-18-28)20-22-9-8-10-23(19-22)26(30)29-13-6-3-7-14-29/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3 ZKZFPRUSWCYSGT-UHFFFAOYSA-N 50029257 (3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)phenyl)(piperidin-1-yl)methanone::CHEMBL10085::RWJ-377796::mazapertine::{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60820 103938328 CHEMBL10085 ZINC52956332 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787269 O=P(N1CC1)(N1CC1)N1CC1 InChI=1S/C6H12N3OP/c10-11(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2 FYAMXEPQQLNQDM-UHFFFAOYSA-N 50067462 1-(diaziridin-1-ylphosphoryl)aziridine::CHEMBL670::N,N:N',N':N'',N''-tri-1,2-ethanediylphosphorictriamide(TEPA)::TEPA (possesses cytotoxic activity)::TPEA D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm980284m 10.7270/Q2N87BFW 9767652 Tagmatarchis, N; Thermos, K; Katerinopoulos, HE University of Crete http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11016 103961902 CHEMBL670 C19543 ZINC08214700 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787271 Oc1cccc2CC3C(CCCN3CC#C)Cc12 InChI=1S/C16H19NO/c1-2-8-17-9-4-6-13-10-14-12(11-15(13)17)5-3-7-16(14)18/h1,3,5,7,13,15,18H,4,6,8-11H2 LWAYUBPNHKMRNZ-UHFFFAOYSA-N 50067463 1-Prop-2-ynyl-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]quinolin-6-ol::CHEMBL134273 D(2) dopamine receptor Rattus norvegicus 5110 ChEMBL 10.1021/jm980284m 10.7270/Q2N87BFW 9767652 Tagmatarchis, N; Thermos, K; Katerinopoulos, HE University of Crete http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067463&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44354823 103961903 CHEMBL134273 ZINC12355929 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787281 NC1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2 ASXGAOFCKGHGMF-UHFFFAOYSA-N 81195 (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide::2-aminotetralin-6,7-diol;hydrobromide::6-Amino-5,6,7,8-tetrahydro-naphthalene-2,3-diol::6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::6-azanyl-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide::ADTN::ADTN, (+)::CA inhibitor, 3::CHEMBL26736::MLS002172466::SMR001254097::cid_11957526::cid_3153 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm980284m 10.7270/Q2N87BFW 9767652 Tagmatarchis, N; Thermos, K; Katerinopoulos, HE University of Crete http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81195 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81195&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3153 252657735 CHEMBL26736 ZINC03872370 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787283 Oc1cccc2CC3C(CCCN3C\C=C\I)Cc12 InChI=1S/C16H20INO/c17-7-3-9-18-8-2-5-13-10-14-12(11-15(13)18)4-1-6-16(14)19/h1,3-4,6-7,13,15,19H,2,5,8-11H2/b7-3+ VLADFNAJLNALFZ-XVNBXDOJSA-N 50067467 1-((E)-3-Iodo-allyl)-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]quinolin-6-ol::CHEMBL132304 D(2) dopamine receptor Rattus norvegicus 490 ChEMBL 10.1021/jm980284m 10.7270/Q2N87BFW 9767652 Tagmatarchis, N; Thermos, K; Katerinopoulos, HE University of Crete http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10361722 103961907 CHEMBL132304 ZINC27413660 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774277 CCCCNCc1ccc(CN2CCN(CC2)c2ccccc2OC(C)C)cc1 InChI=1S/C25H37N3O/c1-4-5-14-26-19-22-10-12-23(13-11-22)20-27-15-17-28(18-16-27)24-8-6-7-9-25(24)29-21(2)3/h6-13,21,26H,4-5,14-20H2,1-3H3 KHNQSFSBOKQODI-UHFFFAOYSA-N 50029322 Butyl-{4-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-amine with malleic acid D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029322&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10524752 103938393 ZINC13743873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774280 CC(C)Oc1ccccc1N1CCN(Cc2cccc(COC(C)=O)c2)CC1 InChI=1S/C23H30N2O3/c1-18(2)28-23-10-5-4-9-22(23)25-13-11-24(12-14-25)16-20-7-6-8-21(15-20)17-27-19(3)26/h4-10,15,18H,11-14,16-17H2,1-3H3 OJISGWFVLDLTSW-UHFFFAOYSA-N 50029318 Acetic acid 3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl ester::CHEMBL135676 D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029318&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10714935 103938389 CHEMBL135676 ZINC00834258 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774282 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3C(=O)CCC3=O)c2)CC1 InChI=1S/C25H31N3O3/c1-19(2)31-23-9-4-3-8-22(23)27-14-12-26(13-15-27)17-20-6-5-7-21(16-20)18-28-24(29)10-11-25(28)30/h3-9,16,19H,10-15,17-18H2,1-2H3 YRUAXNHMCUBLPF-UHFFFAOYSA-N 50029321 1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-pyrrolidine-2,5-dione with succinic acid D(2) dopamine receptor Rattus norvegicus 94 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11796455 103938392 ZINC00835565 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774283 CC(C)Oc1ccccc1N1CCN(Cc2cccc(Cn3c(O)c[nH]c3=S)c2)CC1 InChI=1S/C24H30N4O2S/c1-18(2)30-22-9-4-3-8-21(22)27-12-10-26(11-13-27)16-19-6-5-7-20(14-19)17-28-23(29)15-25-24(28)31/h3-9,14-15,18,29H,10-13,16-17H2,1-2H3,(H,25,31) JRESHQJZKQOYJB-UHFFFAOYSA-N 50029299 3-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-2-thioxo-imidazolidin-4-one::CHEMBL334767 D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53970360 103938370 CHEMBL334767 ZINC00837585 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774284 CC(C)Oc1ccccc1N1CCN(Cc2cccc(C)c2)CC1 InChI=1S/C21H28N2O/c1-17(2)24-21-10-5-4-9-20(21)23-13-11-22(12-14-23)16-19-8-6-7-18(3)15-19/h4-10,15,17H,11-14,16H2,1-3H3 JYILCZLSWAOUEZ-UHFFFAOYSA-N 50029312 1-(2-Isopropoxy-phenyl)-4-(3-methyl-benzyl)-piperazine::CHEMBL439607 D(2) dopamine receptor Rattus norvegicus 302 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029312&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44355641 103938383 CHEMBL439607 ZINC27418813 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774285 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774286 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C25H36N4O2/c1-20(2)31-24-9-5-4-8-23(24)28-16-14-27(15-17-28)18-21-11-12-22(26(21)3)19-29-13-7-6-10-25(29)30/h4-5,8-9,11-12,20H,6-7,10,13-19H2,1-3H3 BLFPEKXTSDYQOQ-UHFFFAOYSA-N 50001869 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL428175::RWJ-25730 D(2) dopamine receptor Rattus norvegicus 0.80 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9910257 103916236 CHEMBL428175 ZINC53255684 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774287 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCC3)cc2)CC1 InChI=1S/C25H35N3O/c1-21(2)29-25-8-4-3-7-24(25)28-17-15-27(16-18-28)20-23-11-9-22(10-12-23)19-26-13-5-6-14-26/h3-4,7-12,21H,5-6,13-20H2,1-2H3 FQWVDNDCLCTKQZ-UHFFFAOYSA-N 50029304 1-(2-Isopropoxy-phenyl)-4-(4-pyrrolidin-1-ylmethyl-benzyl)-piperazine::CHEMBL135246 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029304&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10524634 103938375 CHEMBL135246 ZINC53204416 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774288 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNS(C)(=O)=O)c2)CC1 InChI=1S/C22H31N3O3S/c1-18(2)28-22-10-5-4-9-21(22)25-13-11-24(12-14-25)17-20-8-6-7-19(15-20)16-23-29(3,26)27/h4-10,15,18,23H,11-14,16-17H2,1-3H3 BPTUUGKAWBQQFL-UHFFFAOYSA-N 50029307 N-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzyl}-methanesulfonamide with 0.5M of succinic acid D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029307&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669656 103938378 ZINC13743868 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774289 Cc1ccccc1N1CCN(Cc2cccc(c2)C(O)c2ccccc2)CC1 InChI=1S/C25H28N2O/c1-20-8-5-6-13-24(20)27-16-14-26(15-17-27)19-21-9-7-12-23(18-21)25(28)22-10-3-2-4-11-22/h2-13,18,25,28H,14-17,19H2,1H3 LZRZZVVCEUJCBJ-UHFFFAOYSA-N 50029324 CHEMBL340268::Phenyl-[3-(4-o-tolyl-piperazin-1-ylmethyl)-phenyl]-methanol D(2) dopamine receptor Rattus norvegicus 87 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44355601 103938395 CHEMBL340268 ZINC27421386 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774290 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(C)O)CC1 InChI=1S/C22H30N2O2/c1-17(2)26-22-10-5-4-9-21(22)24-13-11-23(12-14-24)16-19-7-6-8-20(15-19)18(3)25/h4-10,15,17-18,25H,11-14,16H2,1-3H3 SVCXFQYPKFXEAC-UHFFFAOYSA-N 50029308 1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-ethanol::CHEMBL341402 D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1021/jm00021a010 10.7270/Q2C53MH2 7473548 Reitz, AB; Baxter, EW; Bennett, DJ; Codd, EE; Jordan, AD; Malloy, EA; Maryanoff, BE; McDonnell, ME; Ortegon, ME; Renzi, MJ R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029308&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10808061 103938379 CHEMBL341402 ZINC13743875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774291 COc1cc2C(CN(CCCCN(C)C)CCc2cc1Cl)c1ccccc1 InChI=1S/C23H31ClN2O/c1-25(2)12-7-8-13-26-14-11-19-15-22(24)23(27-3)16-20(19)21(17-26)18-9-5-4-6-10-18/h4-6,9-10,15-16,21H,7-8,11-14,17H2,1-3H3 WOPDWQCRTGCGSI-UHFFFAOYSA-N 50029337 CHEMBL132981::[4-(7-Chloro-8-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-butyl]-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 9150 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10834067 103938408 CHEMBL132981 ZINC13743891 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774292 NCCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C20H25ClN2O/c21-19-12-16-8-11-23(10-5-4-9-22)14-18(17(16)13-20(19)24)15-6-2-1-3-7-15/h1-3,6-7,12-13,18,24H,4-5,8-11,14,22H2 SBNSZHJZYONSNC-UHFFFAOYSA-N 50029339 3-(4-Amino-butyl)-8-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL133094 D(2) dopamine receptor Rattus norvegicus 4280 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10665177 103938410 CHEMBL133094 ZINC13743899 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774293 CCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C20H24ClNO/c1-2-3-10-22-11-9-16-12-19(21)20(23)13-17(16)18(14-22)15-7-5-4-6-8-15/h4-8,12-13,18,23H,2-3,9-11,14H2,1H3 XSXUSVIDKUVHNZ-UHFFFAOYSA-N 50029338 3-Butyl-8-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL132545 D(2) dopamine receptor Rattus norvegicus 2360 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10758760 103938409 CHEMBL132545 ZINC13743903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774295 CN(C)CCCCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C24H33ClN2O/c1-26(2)13-8-3-4-9-14-27-15-12-20-16-23(25)24(28)17-21(20)22(18-27)19-10-6-5-7-11-19/h5-7,10-11,16-17,22,28H,3-4,8-9,12-15,18H2,1-2H3 ZTSNZIXPBUGZCP-UHFFFAOYSA-N 50029340 8-Chloro-3-(6-dimethylamino-hexyl)-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL108764 D(2) dopamine receptor Rattus norvegicus 3450 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952858 103938411 CHEMBL108764 ZINC03806141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774300 CNCCCCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C23H31ClN2O/c1-25-12-7-2-3-8-13-26-14-11-19-15-22(24)23(27)16-20(19)21(17-26)18-9-5-4-6-10-18/h4-6,9-10,15-16,21,25,27H,2-3,7-8,11-14,17H2,1H3 VUYOCXNTVLFCAE-UHFFFAOYSA-N 50029344 8-Chloro-3-(6-methylamino-hexyl)-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL108480 D(2) dopamine receptor Rattus norvegicus 3570 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620219 103938415 CHEMBL108480 ZINC13743911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774301 CNCCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C21H27ClN2O/c1-23-10-5-6-11-24-12-9-17-13-20(22)21(25)14-18(17)19(15-24)16-7-3-2-4-8-16/h2-4,7-8,13-14,19,23,25H,5-6,9-12,15H2,1H3 JQYPCXSMFIVWTI-UHFFFAOYSA-N 50029343 8-Chloro-3-(4-methylamino-butyl)-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL422267 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10570422 103938414 CHEMBL422267 ZINC13743901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774303 COc1cc2CCN(CCCCN(C)C)CC(c3ccccc3)c2cc1OC InChI=1S/C24H34N2O2/c1-25(2)13-8-9-14-26-15-12-20-16-23(27-3)24(28-4)17-21(20)22(18-26)19-10-6-5-7-11-19/h5-7,10-11,16-17,22H,8-9,12-15,18H2,1-4H3 GYOHDBSQAACLOI-UHFFFAOYSA-N 50029345 CHEMBL133086::[4-(7,8-Dimethoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-butyl]-dimethyl-amine D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10596089 103938416 CHEMBL133086 ZINC13743913 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774308 CN(C)CCCCN1CCc2cc(Br)c(O)cc2C(C1)c1ccccc1 InChI=1S/C22H29BrN2O/c1-24(2)11-6-7-12-25-13-10-18-14-21(23)22(26)15-19(18)20(16-25)17-8-4-3-5-9-17/h3-5,8-9,14-15,20,26H,6-7,10-13,16H2,1-2H3 AEFMBWDXTMRYHD-UHFFFAOYSA-N 50029347 8-Bromo-3-(4-dimethylamino-butyl)-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL135616 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740666 103938418 CHEMBL135616 ZINC13743895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774309 Oc1cc2C(CN(CCCCCCNC=O)CCc2cc1Cl)c1ccccc1 InChI=1S/C23H29ClN2O2/c24-22-14-19-10-13-26(12-7-2-1-6-11-25-17-27)16-21(20(19)15-23(22)28)18-8-4-3-5-9-18/h3-5,8-9,14-15,17,21,28H,1-2,6-7,10-13,16H2,(H,25,27) KTVVZLGUFWSVBE-UHFFFAOYSA-N 50029348 CHEMBL137636::N-[6-(7-Chloro-8-hydroxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-hexyl]-formamide D(2) dopamine receptor Rattus norvegicus 2030 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811026 103938419 CHEMBL137636 C06049 ZINC13743909 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774312 NCCCCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C22H29ClN2O/c23-21-14-18-10-13-25(12-7-2-1-6-11-24)16-20(19(18)15-22(21)26)17-8-4-3-5-9-17/h3-5,8-9,14-15,20,26H,1-2,6-7,10-13,16,24H2 AXHDPJPTYSIEGZ-UHFFFAOYSA-N 50029346 3-(6-Amino-hexyl)-8-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL137637 D(2) dopamine receptor Rattus norvegicus 2490 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10667043 103938417 CHEMBL137637 ZINC13743907 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774316 NCCCC(=O)N1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C20H23ClN2O2/c21-18-11-15-8-10-23(20(25)7-4-9-22)13-17(16(15)12-19(18)24)14-5-2-1-3-6-14/h1-3,5-6,11-12,17,24H,4,7-10,13,22H2 QCFYGJJTWBCGJI-UHFFFAOYSA-N 50029342 4-Amino-1-(7-chloro-8-hydroxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-butan-1-one::CHEMBL422086 D(2) dopamine receptor Rattus norvegicus 7410 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10689791 103938413 CHEMBL422086 ZINC13743905 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774318 COc1cc2C(CN(CCCCN(C)C)CCc2cc1Br)c1ccccc1 InChI=1S/C23H31BrN2O/c1-25(2)12-7-8-13-26-14-11-19-15-22(24)23(27-3)16-20(19)21(17-26)18-9-5-4-6-10-18/h4-6,9-10,15-16,21H,7-8,11-14,17H2,1-3H3 HXQUNKIFYHBJDP-UHFFFAOYSA-N 50029350 CHEMBL135834::[4-(7-Bromo-8-methoxy-1-phenyl-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-butyl]-dimethyl-amine D(2) dopamine receptor Rattus norvegicus 2490 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10788806 103938421 CHEMBL135834 ZINC13743893 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774319 CN(C)CCCCN1CCc2cc(O)c(O)cc2C(C1)c1ccccc1 InChI=1S/C22H30N2O2/c1-23(2)11-6-7-12-24-13-10-18-14-21(25)22(26)15-19(18)20(16-24)17-8-4-3-5-9-17/h3-5,8-9,14-15,20,25-26H,6-7,10-13,16H2,1-2H3 KEVIJPFNAZWWIS-UHFFFAOYSA-N 50029349 3-(4-Dimethylamino-butyl)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::CHEMBL137583 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10618131 103938420 CHEMBL137583 ZINC13743897 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774320 CN(C)CCCCN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1 InChI=1S/C22H29ClN2O/c1-24(2)11-6-7-12-25-13-10-18-14-21(23)22(26)15-19(18)20(16-25)17-8-4-3-5-9-17/h3-5,8-9,14-15,20,26H,6-7,10-13,16H2,1-2H3 JMLZYVMMUDKHMM-UHFFFAOYSA-N 50029341 8-Chloro-3-(4-dimethylamino-butyl)-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol::CHEMBL114375 D(2) dopamine receptor Rattus norvegicus 4130 ChEMBL 10.1021/jm00021a018 10.7270/Q27D2VSB 7473556 Shah, JH; Izenwasser, S; Geter-Douglass, B; Witkin, JM; Newman, AH National Institutes of Health http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9842468 103938412 CHEMBL114375 ZINC03806137 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777916 Cc1cccc(c1)N1CCN(CCCCN2CSCC2=O)CC1 InChI=1S/C18H27N3OS/c1-16-5-4-6-17(13-16)20-11-9-19(10-12-20)7-2-3-8-21-15-23-14-18(21)22/h4-6,13H,2-3,7-12,14-15H2,1H3 KARSQFDNXAMHMU-UHFFFAOYSA-N 50053729 3-[4-(4-m-Tolyl-piperazin-1-yl)-butyl]-thiazolidin-4-one::CHEMBL130035 D(2) dopamine receptor Rattus norvegicus 12600 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053729&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10759099 103950408 CHEMBL130035 ZINC01547051 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777917 CC1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H32N4OS2/c1-18-27(22(28)23(29-18)10-4-5-11-23)13-7-6-12-25-14-16-26(17-15-25)21-19-8-2-3-9-20(19)30-24-21/h2-3,8-9,18H,4-7,10-17H2,1H3 PAUMQFJGPJRGAD-UHFFFAOYSA-N 50053710 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2-methyl-1-thia-3-aza-spiro[4.4]nonan-4-one::CHEMBL131721 D(2) dopamine receptor Rattus norvegicus 154 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053710&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10551296 103950389 CHEMBL131721 ZINC13759401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783454 Oc1ccc2CCC(CNCCCCc3ccccc3)Oc2c1 InChI=1S/C20H25NO2/c22-18-11-9-17-10-12-19(23-20(17)14-18)15-21-13-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9,11,14,19,21-22H,4-5,8,10,12-13,15H2 FIKHCMJSJBBEJM-UHFFFAOYSA-N 50061632 2-[(4-Phenyl-butylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL134663 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061632&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10662838 103957182 CHEMBL134663 ZINC13775956 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785457 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCc3ccccc23)CC1 InChI=1S/C29H33N3O2/c1-22(2)34-28-13-6-5-12-27(28)31-18-16-30(17-19-31)21-23-8-7-10-25(20-23)29(33)32-15-14-24-9-3-4-11-26(24)32/h3-13,20,22H,14-19,21H2,1-2H3 CBLUNKVNKSMVMO-UHFFFAOYSA-N 50064552 (2,3-Dihydro-indol-1-yl)-{3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL61440 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064552&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10718592 103959569 CHEMBL61440 ZINC13779664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785458 CCOc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCCC2)CC1 InChI=1S/C26H35N3O2/c1-2-31-25-13-6-5-12-24(25)28-18-16-27(17-19-28)21-22-10-9-11-23(20-22)26(30)29-14-7-3-4-8-15-29/h5-6,9-13,20H,2-4,7-8,14-19,21H2,1H3 FRUUDFUCYLDNKU-UHFFFAOYSA-N 50064547 Azepan-1-yl-{3-[4-(2-ethoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL59855 D(2) dopamine receptor Rattus norvegicus 57 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064547&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10835967 103959564 CHEMBL59855 ZINC13779639 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785459 O=C(N1CCCCC1)c1cccc(CN2CCN(CC2)c2nsc3ccccc23)c1 InChI=1S/C24H28N4OS/c29-24(28-11-4-1-5-12-28)20-8-6-7-19(17-20)18-26-13-15-27(16-14-26)23-21-9-2-3-10-22(21)30-25-23/h2-3,6-10,17H,1,4-5,11-16,18H2 NBQHGNXQTOFSDN-UHFFFAOYSA-N 50064557 CHEMBL59878::[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-ylmethyl)-phenyl]-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10693450 103959574 CHEMBL59878 ZINC12356374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785462 O=C(N1CCCCC1)c1cccc(CN2CCN(CC2)c2cccc3ccccc23)c1 InChI=1S/C27H31N3O/c31-27(30-14-4-1-5-15-30)24-11-6-8-22(20-24)21-28-16-18-29(19-17-28)26-13-7-10-23-9-2-3-12-25(23)26/h2-3,6-13,20H,1,4-5,14-19,21H2 GZJOGWXWIJOLEL-UHFFFAOYSA-N 50064558 CHEMBL59853::[3-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-phenyl]-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 124 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811698 103959575 CHEMBL59853 ZINC13779659 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785464 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)S(=O)(=O)N2CCCCC2)CC1 InChI=1S/C25H35N3O3S/c1-21(2)31-25-12-5-4-11-24(25)27-17-15-26(16-18-27)20-22-9-8-10-23(19-22)32(29,30)28-13-6-3-7-14-28/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3 XSDARYRXXMUVBS-UHFFFAOYSA-N 50064556 1-(2-Isopropoxy-phenyl)-4-[3-(piperidine-1-sulfonyl)-benzyl]-piperazine::CHEMBL301465 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10647520 103959573 CHEMBL301465 ZINC13779672 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785465 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(N)=O)CC1 InChI=1S/C21H27N3O2/c1-16(2)26-20-9-4-3-8-19(20)24-12-10-23(11-13-24)15-17-6-5-7-18(14-17)21(22)25/h3-9,14,16H,10-13,15H2,1-2H3,(H2,22,25) GCZJGOGQCYPVPH-UHFFFAOYSA-N 50064544 3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzamide::CHEMBL60110 D(2) dopamine receptor Rattus norvegicus 146 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522025 103959561 CHEMBL60110 ZINC13779649 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785466 O=C(N1CCCCC1)c1cccc(CN2CCN(CC2)C2COc3ccccc3O2)c1 InChI=1S/C25H31N3O3/c29-25(28-11-4-1-5-12-28)21-8-6-7-20(17-21)18-26-13-15-27(16-14-26)24-19-30-22-9-2-3-10-23(22)31-24/h2-3,6-10,17,24H,1,4-5,11-16,18-19H2 DGVIXVQUHJOVDU-UHFFFAOYSA-N 50064537 CHEMBL293658::{3-[4-(2,3-Dihydro-benzo[1,4]dioxin-2-yl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064537&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669879 103959554 CHEMBL293658 ZINC22938975 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785471 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCCCC2)CC1 InChI=1S/C28H39N3O2/c1-23(2)33-27-14-7-6-13-26(27)30-19-17-29(18-20-30)22-24-11-10-12-25(21-24)28(32)31-15-8-4-3-5-9-16-31/h6-7,10-14,21,23H,3-5,8-9,15-20,22H2,1-2H3 LAZZWNWLZKNZQI-UHFFFAOYSA-N 50064536 Azocan-1-yl-{3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL303982 D(2) dopamine receptor Rattus norvegicus 5.3 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064536&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797769 103959553 CHEMBL303982 ZINC13779650 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785472 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCC2)CC1 InChI=1S/C25H33N3O2/c1-20(2)30-24-11-4-3-10-23(24)27-16-14-26(15-17-27)19-21-8-7-9-22(18-21)25(29)28-12-5-6-13-28/h3-4,7-11,18,20H,5-6,12-17,19H2,1-2H3 XRXBJPTUUYTFJY-UHFFFAOYSA-N 50064539 CHEMBL441795::{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-pyrrolidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064539&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10835251 103959556 CHEMBL441795 ZINC12356375 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785473 FC(F)(F)c1cccc(c1)N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C24H28F3N3O/c25-24(26,27)21-8-5-9-22(17-21)29-14-12-28(13-15-29)18-19-6-4-7-20(16-19)23(31)30-10-2-1-3-11-30/h4-9,16-17H,1-3,10-15,18H2 DHBAVPRIEVIAEK-UHFFFAOYSA-N 50064559 CHEMBL61470::Piperidin-1-yl-{3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone D(2) dopamine receptor Rattus norvegicus 682 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717561 103959576 CHEMBL61470 ZINC13779646 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785474 CC(C)Oc1ccccc1C1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C27H36N2O2/c1-21(2)31-26-12-5-4-11-25(26)23-13-17-28(18-14-23)20-22-9-8-10-24(19-22)27(30)29-15-6-3-7-16-29/h4-5,8-12,19,21,23H,3,6-7,13-18,20H2,1-2H3 VYXVWGFEAFGRIW-UHFFFAOYSA-N 50064564 CHEMBL64528::{3-[4-(2-Isopropoxy-phenyl)-piperidin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 0.90 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10409903 103959581 CHEMBL64528 ZINC13779673 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785477 COCCN1CCN(Cc2cccc(c2)C(=O)N2CCCCCC2)CC1 InChI=1S/C21H33N3O2/c1-26-16-15-22-11-13-23(14-12-22)18-19-7-6-8-20(17-19)21(25)24-9-4-2-3-5-10-24/h6-8,17H,2-5,9-16,18H2,1H3 RHVWACZNCVCYSL-UHFFFAOYSA-N 50064555 Azepan-1-yl-{3-[4-(2-methoxy-ethyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL294409 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064555 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064555&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594645 103959572 CHEMBL294409 ZINC22938988 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785478 CC(C)Oc1ccccc1N1CCN(CC1)C(C)c1cccc(c1)C(=O)N1CCCCC1 InChI=1S/C27H37N3O2/c1-21(2)32-26-13-6-5-12-25(26)29-18-16-28(17-19-29)22(3)23-10-9-11-24(20-23)27(31)30-14-7-4-8-15-30/h5-6,9-13,20-22H,4,7-8,14-19H2,1-3H3 MFZUUTXPCFSYKC-UHFFFAOYSA-N 50064560 (3-{1-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-ethyl}-phenyl)-piperidin-1-yl-methanone::CHEMBL58299 D(2) dopamine receptor Rattus norvegicus 122 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10836647 103959577 CHEMBL58299 ZINC13779668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785480 CC(C)Oc1cc(F)ccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C26H34FN3O2/c1-20(2)32-25-18-23(27)9-10-24(25)29-15-13-28(14-16-29)19-21-7-6-8-22(17-21)26(31)30-11-4-3-5-12-30/h6-10,17-18,20H,3-5,11-16,19H2,1-2H3 HLWIRJJTVSVAPM-UHFFFAOYSA-N 50064528 CHEMBL60675::{3-[4-(4-Fluoro-2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10836812 103959545 CHEMBL60675 ZINC13779656 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785483 [O-][N+](=O)c1cccc(c1)N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C23H28N4O3/c28-23(26-10-2-1-3-11-26)20-7-4-6-19(16-20)18-24-12-14-25(15-13-24)21-8-5-9-22(17-21)27(29)30/h4-9,16-17H,1-3,10-15,18H2 PCLKHRFRBPWQDZ-UHFFFAOYSA-N 50064530 CHEMBL64678::{3-[4-(3-Nitro-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669186 103959547 CHEMBL64678 ZINC13779647 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785484 CCCc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C26H35N3O/c1-2-9-23-11-4-5-13-25(23)28-18-16-27(17-19-28)21-22-10-8-12-24(20-22)26(30)29-14-6-3-7-15-29/h4-5,8,10-13,20H,2-3,6-7,9,14-19,21H2,1H3 BHGFOJKWEXFBRE-UHFFFAOYSA-N 50064562 CHEMBL292752::Piperidin-1-yl-{3-[4-(2-propyl-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811283 103959579 CHEMBL292752 ZINC13779645 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785487 FC(F)(F)c1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C24H28F3N3O/c25-24(26,27)21-9-2-3-10-22(21)29-15-13-28(14-16-29)18-19-7-6-8-20(17-19)23(31)30-11-4-1-5-12-30/h2-3,6-10,17H,1,4-5,11-16,18H2 RPXWZKCAHYGWQO-UHFFFAOYSA-N 50064534 CHEMBL413546::Piperidin-1-yl-{3-[4-(2-trifluoromethyl-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574711 103959551 CHEMBL413546 ZINC13779641 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785488 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N(C)C2CCCCC2)CC1 InChI=1S/C28H39N3O2/c1-22(2)33-27-15-8-7-14-26(27)31-18-16-30(17-19-31)21-23-10-9-11-24(20-23)28(32)29(3)25-12-5-4-6-13-25/h7-11,14-15,20,22,25H,4-6,12-13,16-19,21H2,1-3H3 OWAFKUCCSIAXDM-UHFFFAOYSA-N 50064568 CHEMBL292107::N-Cyclohexyl-3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-N-methyl-benzamide D(2) dopamine receptor Rattus norvegicus 5.4 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599634 103959585 CHEMBL292107 ZINC13779654 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785489 CC(C)Oc1ccccc1C1(O)CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C27H36N2O3/c1-21(2)32-25-12-5-4-11-24(25)27(31)13-17-28(18-14-27)20-22-9-8-10-23(19-22)26(30)29-15-6-3-7-16-29/h4-5,8-12,19,21,31H,3,6-7,13-18,20H2,1-2H3 TWXBHMQLKGPCTM-UHFFFAOYSA-N 50064551 CHEMBL61478::{3-[4-Hydroxy-4-(2-isopropoxy-phenyl)-piperidin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 37 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064551&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10526928 103959568 CHEMBL61478 ZINC13779674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785490 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785495 O=C(N1CCCCC1)c1cccc(CN2CCN(CC2)c2ccc3ccoc3c2)c1 InChI=1S/C25H29N3O2/c29-25(28-10-2-1-3-11-28)22-6-4-5-20(17-22)19-26-12-14-27(15-13-26)23-8-7-21-9-16-30-24(21)18-23/h4-9,16-18H,1-3,10-15,19H2 QTWVKTIFVJAWQC-UHFFFAOYSA-N 50064563 CHEMBL61816::[3-(4-Benzofuran-6-yl-piperazin-1-ylmethyl)-phenyl]-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692539 103959580 CHEMBL61816 ZINC12356382 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785497 CCN(CC)C(=O)c1cccc(CN2CCN(CC2)c2ccccc2OC(C)C)c1 InChI=1S/C25H35N3O2/c1-5-27(6-2)25(29)22-11-9-10-21(18-22)19-26-14-16-28(17-15-26)23-12-7-8-13-24(23)30-20(3)4/h7-13,18,20H,5-6,14-17,19H2,1-4H3 OWBKZJDQODQYJR-UHFFFAOYSA-N 50064570 CHEMBL64227::N,N-Diethyl-3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzamide D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10692892 103959587 CHEMBL64227 ZINC13779651 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785499 CCCCN(CCCC)C(=O)c1cccc(CN2CCN(CC2)c2ccccc2OC(C)C)c1 InChI=1S/C29H43N3O2/c1-5-7-16-32(17-8-6-2)29(33)26-13-11-12-25(22-26)23-30-18-20-31(21-19-30)27-14-9-10-15-28(27)34-24(3)4/h9-15,22,24H,5-8,16-21,23H2,1-4H3 MPYXUZCMIJMANC-UHFFFAOYSA-N 50064565 CHEMBL59167::N,N-Dibutyl-3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzamide D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11798397 103959582 CHEMBL59167 ZINC13779652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785501 Clc1cccc(c1)N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C23H28ClN3O/c24-21-8-5-9-22(17-21)26-14-12-25(13-15-26)18-19-6-4-7-20(16-19)23(28)27-10-2-1-3-11-27/h4-9,16-17H,1-3,10-15,18H2 YKIZYXJHWPXPDB-UHFFFAOYSA-N 50064569 CHEMBL61117::{3-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 347 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795120 103959586 CHEMBL61117 ZINC12356259 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785503 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCCC2)CC1 InChI=1S/C27H37N3O2/c1-22(2)32-26-13-6-5-12-25(26)29-18-16-28(17-19-29)21-23-10-9-11-24(20-23)27(31)30-14-7-3-4-8-15-30/h5-6,9-13,20,22H,3-4,7-8,14-19,21H2,1-2H3 BPZZLFFRDZMYDZ-UHFFFAOYSA-N 50064548 Azepan-1-yl-{3-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL64702 D(2) dopamine receptor Rattus norvegicus 6.3 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797167 103959565 CHEMBL64702 ZINC13779640 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785505 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2=O)CC1 InChI=1S/C26H33N3O3/c1-20(2)32-24-11-4-3-10-23(24)28-16-14-27(15-17-28)19-21-8-7-9-22(18-21)26(31)29-13-6-5-12-25(29)30/h3-4,7-11,18,20H,5-6,12-17,19H2,1-2H3 NBXLYJYHAMUDKN-UHFFFAOYSA-N 50064566 1-{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-benzoyl}-piperidin-2-one::CHEMBL279837 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10836643 103959583 CHEMBL279837 ZINC13779666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785508 OCCN1CCN(Cc2cccc(c2)C(=O)N2CCCCCC2)CC1 InChI=1S/C20H31N3O2/c24-15-14-21-10-12-22(13-11-21)17-18-6-5-7-19(16-18)20(25)23-8-3-1-2-4-9-23/h5-7,16,24H,1-4,8-15,17H2 DRBAAJDUTMDNTA-UHFFFAOYSA-N 50064532 Azepan-1-yl-{3-[4-(2-hydroxy-ethyl)-piperazin-1-ylmethyl]-phenyl}-methanone::CHEMBL59801 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593648 103959549 CHEMBL59801 ZINC22938985 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785509 Clc1ccc(cc1)N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C23H28ClN3O/c24-21-7-9-22(10-8-21)26-15-13-25(14-16-26)18-19-5-4-6-20(17-19)23(28)27-11-2-1-3-12-27/h4-10,17H,1-3,11-16,18H2 TVHAMCUTCKGIAN-UHFFFAOYSA-N 50064540 CHEMBL64547::{3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064540&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620847 103959557 CHEMBL64547 ZINC13779648 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785510 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=S)N2CCCCC2)CC1 InChI=1S/C26H35N3OS/c1-21(2)30-25-12-5-4-11-24(25)28-17-15-27(16-18-28)20-22-9-8-10-23(19-22)26(31)29-13-6-3-7-14-29/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3 CFUYCRNXBBKXTF-UHFFFAOYSA-N 50064561 CHEMBL60122::{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanethione D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797263 103959578 CHEMBL60122 ZINC13779671 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785514 CC(C)Oc1ccccc1N1CCN(CCc2ccc(cc2)C(=O)N2CCCCC2)CC1 InChI=1S/C27H37N3O2/c1-22(2)32-26-9-5-4-8-25(26)29-20-18-28(19-21-29)17-14-23-10-12-24(13-11-23)27(31)30-15-6-3-7-16-30/h4-5,8-13,22H,3,6-7,14-21H2,1-2H3 JJFADYLYNRZMEB-UHFFFAOYSA-N 50064553 (4-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-ethyl}-phenyl)-piperidin-1-yl-methanone::CHEMBL62150 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064553&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10836648 103959570 CHEMBL62150 ZINC13779669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785515 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785516 CN1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C18H27N3O/c1-19-10-12-20(13-11-19)15-16-6-5-7-17(14-16)18(22)21-8-3-2-4-9-21/h5-7,14H,2-4,8-13,15H2,1H3 PICQQMGTBBGDGI-UHFFFAOYSA-N 50064567 CHEMBL59954::[3-(4-Methyl-piperazin-1-ylmethyl)-phenyl]-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm970164z 10.7270/Q2KK9CG0 9622541 Reitz, AB; Baxter, EW; Codd, EE; Davis, CB; Jordan, AD; Maryanoff, BE; Maryanoff, CA; McDonnell, ME; Powell, ET; Renzi, MJ; Schott, MR; Scott, MK; Shank, RP; Vaught, JL R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10828160 103959584 CHEMBL59954 ZINC22938981 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764930 CN(C)[C@@H]1C[C@@H](c2ccccc2)c2cc(O)c(Cl)cc2C1 InChI=1S/C18H20ClNO/c1-20(2)14-8-13-9-17(19)18(21)11-16(13)15(10-14)12-6-4-3-5-7-12/h3-7,9,11,14-15,21H,8,10H2,1-2H3/t14-,15-/m0/s1 XZCKHECUBFUSAR-GJZGRUSLSA-N 50040283 3-Chloro-6-dimethylamino-6-methyl-8-phenyl-5,6,7,8-tetrahydro-naphthalen-2-ol; hydrochloride::CHEMBL545477 D(2) dopamine receptor Rattus norvegicus 4130 ChEMBL 10.1021/jm00069a013 10.7270/Q2C53MGM 8102651 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 192611 103972343 CHEMBL545477 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764933 C=CCNC1CC(c2ccccc2)c2ccccc2C1 InChI=1S/C19H21N/c1-2-12-20-17-13-16-10-6-7-11-18(16)19(14-17)15-8-4-3-5-9-15/h2-11,17,19-20H,1,12-14H2 CVGHMODPNXTUCI-UHFFFAOYSA-N 50040286 CHEMBL542419::trans-Allyl-(4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus 6000 ChEMBL 10.1021/jm00069a013 10.7270/Q2C53MGM 8102651 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15657214 103972346 CHEMBL542419 ZINC26508025 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764940 C=CCN(CC=C)C1CC(c2ccccc2)c2ccccc2C1 InChI=1S/C22H25N/c1-3-14-23(15-4-2)20-16-19-12-8-9-13-21(19)22(17-20)18-10-6-5-7-11-18/h3-13,20,22H,1-2,14-17H2 VRNFGNXKGCVWKG-UHFFFAOYSA-N 50040285 CHEMBL539274::trans-Diallyl-(4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus 4000 ChEMBL 10.1021/jm00069a013 10.7270/Q2C53MGM 8102651 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040285&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15657216 103972345 CHEMBL539274 ZINC26574955 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764945 NC1CC(c2ccccc2)c2ccccc2C1 InChI=1S/C16H17N/c17-14-10-13-8-4-5-9-15(13)16(11-14)12-6-2-1-3-7-12/h1-9,14,16H,10-11,17H2 ZPTITOXHTKKBPT-UHFFFAOYSA-N 50040289 CHEMBL544078::trans-4-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-ylamine; hydrochloride D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00069a013 10.7270/Q2C53MGM 8102651 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15657191 103972349 CHEMBL544078 ZINC26569594 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764960 CNC1CC(c2ccccc2)c2cc(O)c(Cl)cc2C1 InChI=1S/C17H18ClNO/c1-19-13-7-12-8-16(18)17(20)10-15(12)14(9-13)11-5-3-2-4-6-11/h2-6,8,10,13-14,19-20H,7,9H2,1H3 XBEPZFYXDLYZOH-UHFFFAOYSA-N 50040284 3-Chloro-6-methylamino-8-phenyl-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL87321::trans-3-Chloro-6-methylamino-8-phenyl-5,6,7,8-tetrahydro-naphthalen-2-ol D(2) dopamine receptor Rattus norvegicus 10000 ChEMBL 10.1021/jm00069a013 10.7270/Q2C53MGM 8102651 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040284&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15657207 103972344 CHEMBL87321 ZINC26574959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783455 Nc1cc(OCCCNCC2CCc3ccc(O)cc3O2)ccc1Cl InChI=1S/C19H23ClN2O3/c20-17-7-6-15(11-18(17)21)24-9-1-8-22-12-16-5-3-13-2-4-14(23)10-19(13)25-16/h2,4,6-7,10-11,16,22-23H,1,3,5,8-9,12,21H2 AVVHLOOXCWDKCY-UHFFFAOYSA-N 50061636 2-{[3-(3-Amino-4-chloro-phenoxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL135201 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594856 103957186 CHEMBL135201 ZINC13775923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783463 Oc1ccc2CCC(CNCc3cccs3)Oc2c1 InChI=1S/C15H17NO2S/c17-12-5-3-11-4-6-13(18-15(11)8-12)9-16-10-14-2-1-7-19-14/h1-3,5,7-8,13,16-17H,4,6,9-10H2 KBNHFHXXRALJJY-UHFFFAOYSA-N 50061639 2-{[(Thiophen-2-ylmethyl)-amino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL337724 D(2) dopamine receptor Rattus norvegicus 2.8 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061639&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10850012 103957189 CHEMBL337724 ZINC13775959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783465 OCCCNCC1CCc2ccccc2O1 InChI=1S/C13H19NO2/c15-9-3-8-14-10-12-7-6-11-4-1-2-5-13(11)16-12/h1-2,4-5,12,14-15H,3,6-10H2 FUWHJYUJXZYSCO-UHFFFAOYSA-N 50061641 3-[(Chroman-2-ylmethyl)-amino]-propan-1-ol; hydrochloride::CHEMBL545078 D(2) dopamine receptor Rattus norvegicus 294 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061641&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44356021 103957191 CHEMBL545078 ZINC13775943 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783466 Oc1ccc2CCC(CNCCCOc3ccccc3)Oc2c1 InChI=1S/C19H23NO3/c21-16-9-7-15-8-10-18(23-19(15)13-16)14-20-11-4-12-22-17-5-2-1-3-6-17/h1-3,5-7,9,13,18,20-21H,4,8,10-12,14H2 OSKPDOAXGBYHKG-UHFFFAOYSA-N 50061638 2-[(3-Phenoxy-propylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL134448 D(2) dopamine receptor Rattus norvegicus 0.50 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10686667 103957188 CHEMBL134448 ZINC13775927 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783470 Oc1ccc2CCC(CNCCCOc3ccc4CCCNc4c3)Oc2c1 InChI=1S/C22H28N2O3/c25-18-7-4-17-6-9-20(27-22(17)13-18)15-23-10-2-12-26-19-8-5-16-3-1-11-24-21(16)14-19/h4-5,7-8,13-14,20,23-25H,1-3,6,9-12,15H2 JOGUPOAVWOLLLX-UHFFFAOYSA-N 50061643 2-{[3-(1,2,3,4-Tetrahydro-quinolin-7-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL424087 D(2) dopamine receptor Rattus norvegicus 0.70 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10571059 103957193 CHEMBL424087 ZINC12356233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783472 Cc1ccc(CNCC2CCc3ccc(NS(C)(=O)=O)cc3O2)cc1 InChI=1S/C19H24N2O3S/c1-14-3-5-15(6-4-14)12-20-13-18-10-8-16-7-9-17(11-19(16)24-18)21-25(2,22)23/h3-7,9,11,18,20-21H,8,10,12-13H2,1-2H3 DPKPCJJKKOEQBE-UHFFFAOYSA-N 50061645 CHEMBL133367::N-{2-[(4-Methyl-benzylamino)-methyl]-chroman-7-yl}-methanesulfonamide; oxalic acid D(2) dopamine receptor Rattus norvegicus 7.1 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061645&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10666241 103957195 CHEMBL133367 ZINC13775978 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783473 CCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C13H19NO2/c1-2-7-14-9-12-6-4-10-3-5-11(15)8-13(10)16-12/h3,5,8,12,14-15H,2,4,6-7,9H2,1H3 PEHTUJKNDCNRDK-UHFFFAOYSA-N 50061652 2-Propylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135636 D(2) dopamine receptor Rattus norvegicus 6.9 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061652&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10513189 103957202 CHEMBL135636 ZINC03959253 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783474 Oc1ccc2CCC(CNCCCOc3ccc4ocnc4c3)Oc2c1 InChI=1S/C20H22N2O4/c23-15-4-2-14-3-5-17(26-20(14)10-15)12-21-8-1-9-24-16-6-7-19-18(11-16)22-13-25-19/h2,4,6-7,10-11,13,17,21,23H,1,3,5,8-9,12H2 DAQQNLJMVSQRSY-UHFFFAOYSA-N 50061649 2-{[3-(Benzooxazol-5-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134677 D(2) dopamine receptor Rattus norvegicus 0.40 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10665823 103957199 CHEMBL134677 ZINC13775931 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783484 Oc1ccc2CCC(CNCC3CCCCC3)Oc2c1 InChI=1S/C17H25NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h6,8,10,13,16,18-19H,1-5,7,9,11-12H2 QBNAZFPOIWIARB-UHFFFAOYSA-N 50061660 2-[(Cyclohexylmethyl-amino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL135137 D(2) dopamine receptor Rattus norvegicus 7.2 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061660&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10826275 103957210 CHEMBL135137 ZINC13775960 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783488 CCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C14H21NO2/c1-2-3-8-15-10-13-7-5-11-4-6-12(16)9-14(11)17-13/h4,6,9,13,15-16H,2-3,5,7-8,10H2,1H3 PLFNWLNAVFWLFO-UHFFFAOYSA-N 50061644 2-Butylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135116 D(2) dopamine receptor Rattus norvegicus 2.4 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10799761 103957194 CHEMBL135116 ZINC03959252 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783490 Oc1cc2O[C@H](CNCc3ccccc3)CCc2cc1Cl InChI=1S/C17H18ClNO2/c18-15-8-13-6-7-14(21-17(13)9-16(15)20)11-19-10-12-4-2-1-3-5-12/h1-5,8-9,14,19-20H,6-7,10-11H2/t14-/m0/s1 BCTPODDQZONFKA-AWEZNQCLSA-N 50061659 (S)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; oxalic acid::CHEMBL134343 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061659&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10494689 103957209 CHEMBL134343 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783491 CCC(CC)NCC1CCc2ccc(O)cc2O1 InChI=1S/C15H23NO2/c1-3-12(4-2)16-10-14-8-6-11-5-7-13(17)9-15(11)18-14/h5,7,9,12,14,16-17H,3-4,6,8,10H2,1-2H3 DXGWEOVPJQPZFA-UHFFFAOYSA-N 50061663 2-[(1-Ethyl-propylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL134931 D(2) dopamine receptor Rattus norvegicus 413 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061663&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10490854 103957213 CHEMBL134931 ZINC13775952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783495 Nc1cccc(OCCCNCC2COc3ccc(O)cc3O2)c1 InChI=1S/C18H22N2O4/c19-13-3-1-4-15(9-13)22-8-2-7-20-11-16-12-23-17-6-5-14(21)10-18(17)24-16/h1,3-6,9-10,16,20-21H,2,7-8,11-12,19H2 XQRSLRUXPXVCRY-UHFFFAOYSA-N 50061650 3-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-2,3-dihydro-benzo[1,4]dioxin-6-ol::CHEMBL135752 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061650&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9949399 103957200 CHEMBL135752 ZINC03779080 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783498 Oc1ccc2CCC(CNCc3ccc(F)cc3)Oc2c1 InChI=1S/C17H18FNO2/c18-14-5-1-12(2-6-14)10-19-11-16-8-4-13-3-7-15(20)9-17(13)21-16/h1-3,5-7,9,16,19-20H,4,8,10-11H2 AYQFVOWZPZLEGQ-UHFFFAOYSA-N 50061657 2-[(4-Fluoro-benzylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL334406 D(2) dopamine receptor Rattus norvegicus 0.80 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061657&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10684699 103957207 CHEMBL334406 ZINC13775972 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783509 Oc1ccc2CCC(CNCCCOc3ccc4ncoc4c3)Oc2c1 InChI=1S/C20H22N2O4/c23-15-4-2-14-3-5-17(26-19(14)10-15)12-21-8-1-9-24-16-6-7-18-20(11-16)25-13-22-18/h2,4,6-7,10-11,13,17,21,23H,1,3,5,8-9,12H2 PPSUFDUYMIFSSO-UHFFFAOYSA-N 50061631 2-{[3-(Benzooxazol-6-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL334616 D(2) dopamine receptor Rattus norvegicus 0.50 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061631&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10784316 103957181 CHEMBL334616 ZINC12356188 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783510 Oc1ccc2CCC(CNCCc3ccccc3)Oc2c1 InChI=1S/C18H21NO2/c20-16-8-6-15-7-9-17(21-18(15)12-16)13-19-11-10-14-4-2-1-3-5-14/h1-6,8,12,17,19-20H,7,9-11,13H2 CPHLCRCURDQKDY-UHFFFAOYSA-N 50061674 2-(Phenethylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL135546 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061674&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10493242 103957224 CHEMBL135546 ZINC12356040 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783513 Nc1cccc(OCCCNC[C@H]2COc3ccc(O)cc3O2)c1 InChI=1S/C18H22N2O4/c19-13-3-1-4-15(9-13)22-8-2-7-20-11-16-12-23-17-6-5-14(21)10-18(17)24-16/h1,3-6,9-10,16,20-21H,2,7-8,11-12,19H2/t16-/m0/s1 XQRSLRUXPXVCRY-INIZCTEOSA-N 50061671 3-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-2,3-dihydro-benzo[1,4]dioxin-6-ol::CHEMBL136635 D(2) dopamine receptor Rattus norvegicus 0.30 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061671&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9927497 103957221 CHEMBL136635 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783516 CC(C)NCC1CCc2ccc(O)cc2O1 InChI=1S/C13H19NO2/c1-9(2)14-8-12-6-4-10-3-5-11(15)7-13(10)16-12/h3,5,7,9,12,14-15H,4,6,8H2,1-2H3 LYVQVYJGNYDXHG-UHFFFAOYSA-N 50061676 2-(Isopropylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL132811 D(2) dopamine receptor Rattus norvegicus 515 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061676&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10609019 103957226 CHEMBL132811 ZINC13775949 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783518 Oc1ccc2CCC(CN3CCc4ccccc4C3)Oc2c1 InChI=1S/C19H21NO2/c21-17-7-5-15-6-8-18(22-19(15)11-17)13-20-10-9-14-3-1-2-4-16(14)12-20/h1-5,7,11,18,21H,6,8-10,12-13H2 IWUPLAFLTUWLMF-UHFFFAOYSA-N 50061654 2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chroman-7-ol; oxalic acid::CHEMBL134808 D(2) dopamine receptor Rattus norvegicus 0.60 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061654&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44356253 103957204 CHEMBL134808 ZINC12356067 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783520 CCCCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C16H25NO2/c1-2-3-4-5-10-17-12-15-9-7-13-6-8-14(18)11-16(13)19-15/h6,8,11,15,17-18H,2-5,7,9-10,12H2,1H3 QNPXMHDZEWNMNS-UHFFFAOYSA-N 50061679 2-Hexylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135222 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10220913 103957229 CHEMBL135222 ZINC03959251 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783523 Oc1ccc2CC[C@H](CNCCCCc3ccccc3)Oc2c1 InChI=1S/C20H25NO2/c22-18-11-9-17-10-12-19(23-20(17)14-18)15-21-13-5-4-8-16-6-2-1-3-7-16/h1-3,6-7,9,11,14,19,21-22H,4-5,8,10,12-13,15H2/t19-/m1/s1 FIKHCMJSJBBEJM-LJQANCHMSA-N 50061682 (R)-2-[(4-Phenyl-butylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL134489 D(2) dopamine receptor Rattus norvegicus 2.8 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061682&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10591141 103957232 CHEMBL134489 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783528 CCCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C15H23NO2/c1-2-3-4-9-16-11-14-8-6-12-5-7-13(17)10-15(12)18-14/h5,7,10,14,16-17H,2-4,6,8-9,11H2,1H3 DOZIVYHWZVQTFR-UHFFFAOYSA-N 50061656 2-Pentylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL340267 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061656&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10777026 103957206 CHEMBL340267 ZINC13775947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783540 OCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C13H19NO3/c15-7-1-6-14-9-12-5-3-10-2-4-11(16)8-13(10)17-12/h2,4,8,12,14-16H,1,3,5-7,9H2 YEENTVNLGWCDRF-UHFFFAOYSA-N 50061670 2-[(3-Hydroxy-propylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL336856 D(2) dopamine receptor Rattus norvegicus 177 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061670&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10799880 103957220 CHEMBL336856 ZINC03959257 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783542 Nc1nccc(OCCCNCC2CCc3ccc(O)cc3O2)n1 InChI=1S/C17H22N4O3/c18-17-20-8-6-16(21-17)23-9-1-7-19-11-14-5-3-12-2-4-13(22)10-15(12)24-14/h2,4,6,8,10,14,19,22H,1,3,5,7,9,11H2,(H2,18,20,21) FZGKVKJMAJFNHI-UHFFFAOYSA-N 50061662 2-{[3-(2-Amino-pyrimidin-4-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134725 D(2) dopamine receptor Rattus norvegicus 0.50 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061662&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640173 103957212 CHEMBL134725 ZINC13775935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50764977 CN(C)[C@]1(C)C[C@@H](c2ccccc2)c2ccccc2C1 InChI=1S/C19H23N/c1-19(20(2)3)13-16-11-7-8-12-17(16)18(14-19)15-9-5-4-6-10-15/h4-12,18H,13-14H2,1-3H3/t18-,19-/m0/s1 YWARPDQQESVVJE-OALUTQOASA-N 50040287 (1R,3S)Dimethyl-(2-methyl-4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine; hydrochloride::(1S, 3R) Dimethyl-(2-methyl-4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine; hydrochloride::CHEMBL542167::Dimethyl-(4-phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus 1500 ChEMBL 10.1021/jm00069a013 10.7270/Q2C53MGM 8102651 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319215 103972347 CHEMBL542167 ZINC26570480 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766901 COc1cccc2C[C@H]3[C@H](CCN3Cc3ccccc3)Cc12 InChI=1S/C20H23NO/c1-22-20-9-5-8-16-13-19-17(12-18(16)20)10-11-21(19)14-15-6-3-2-4-7-15/h2-9,17,19H,10-14H2,1H3/t17-,19+/m1/s1 SRCYZESDHGJOSG-MJGOQNOKSA-N 50034318 (3aS,9aS)-1-Benzyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::1-Benzyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL275057 D(2) dopamine receptor Rattus norvegicus 465 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034318&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10062998 103942519 CHEMBL275057 ZINC13826551 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766905 COc1cccc2C[C@H]3NCC[C@@H]3Cc12 InChI=1S/C13H17NO/c1-15-13-4-2-3-9-8-12-10(5-6-14-12)7-11(9)13/h2-4,10,12,14H,5-8H2,1H3/t10-,12-/m1/s1 OBGADVDRELNMHY-ZYHUDNBSSA-N 50034312 (3aS,9aR)-5-Methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::5-Methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL275480 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034312&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10035788 103942513 CHEMBL275480 ZINC13826584 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774476 COc1ccccc1N1CCN(Cc2ccc(-c3ccccc3)n2C)CC1 InChI=1S/C23H27N3O/c1-24-20(12-13-21(24)19-8-4-3-5-9-19)18-25-14-16-26(17-15-25)22-10-6-7-11-23(22)27-2/h3-13H,14-18H2,1-2H3 NWMABYSDZBQPTK-UHFFFAOYSA-N 50048240 1-(2-Methoxy-phenyl)-4-(1-methyl-5-phenyl-1H-pyrrol-2-ylmethyl)-piperazine::CHEMBL146535 D(2) dopamine receptor Rattus norvegicus 0.80 ChEMBL 10.1021/jm00025a013 10.7270/Q2FX7B33 8523409 Thurkauf, A; Yuan, J; Chen, X; Wasley, JW; Meade, R; Woodruff, KH; Huston, K; Ross, PC Neurogen Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048240 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048240&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44364142 103978766 CHEMBL146535 ZINC27556023 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778183 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778185 CN(CC=C)[C@@H]1Cc2cc(O)ccc2[C@H]1c1ccccc1 InChI=1S/C19H21NO/c1-3-11-20(2)18-13-15-12-16(21)9-10-17(15)19(18)14-7-5-4-6-8-14/h3-10,12,18-19,21H,1,11,13H2,2H3/t18-,19-/m1/s1 IFINZBGVEALRFP-RTBURBONSA-N 50054086 (1R,2R)-2-(Allyl-methyl-amino)-1-phenyl-indan-5-ol::CHEMBL134991 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054086&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10540651 103950744 CHEMBL134991 ZINC27420806 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778186 NCCCN(CCc1ccccc1)C1CCc2c(O)cccc2C1 InChI=1S/C21H28N2O/c22-13-5-14-23(15-12-17-6-2-1-3-7-17)19-10-11-20-18(16-19)8-4-9-21(20)24/h1-4,6-9,19,24H,5,10-16,22H2 OKEDLADWSOZTBR-UHFFFAOYSA-N 50054087 6-[(3-Amino-propyl)-phenethyl-amino]-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL134344 D(2) dopamine receptor Rattus norvegicus 2.7 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054087&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44356095 103950745 CHEMBL134344 ZINC27426012 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778187 N[C@@H]1Cc2cc(O)ccc2[C@H]1c1ccccc1 InChI=1S/C15H15NO/c16-14-9-11-8-12(17)6-7-13(11)15(14)10-4-2-1-3-5-10/h1-8,14-15,17H,9,16H2/t14-,15-/m1/s1 FSUHLVITEOOXIA-HUUCEWRRSA-N 50054085 (1R,2R)-2-Amino-1-phenyl-indan-5-ol::CHEMBL336366 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054085&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10656804 103950743 CHEMBL336366 ZINC27427375 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778188 CCCN(C)[C@@H]1Cc2ccc(O)cc2[C@H]1c1ccccc1 InChI=1S/C19H23NO/c1-3-11-20(2)18-12-15-9-10-16(21)13-17(15)19(18)14-7-5-4-6-8-14/h4-10,13,18-19,21H,3,11-12H2,1-2H3/t18-,19-/m1/s1 JSEXLEGBBZMMOQ-RTBURBONSA-N 50054088 (2R,3R)-2-(Methyl-propyl-amino)-3-phenyl-indan-5-ol::CHEMBL433652 D(2) dopamine receptor Rattus norvegicus 0.34 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054088&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10802788 103950746 CHEMBL433652 ZINC27431219 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778191 CCCN(CCC)[C@@H]1Cc2ccc(O)cc2[C@H]1c1ccccc1 InChI=1S/C21H27NO/c1-3-12-22(13-4-2)20-14-17-10-11-18(23)15-19(17)21(20)16-8-6-5-7-9-16/h5-11,15,20-21,23H,3-4,12-14H2,1-2H3/t20-,21-/m1/s1 BVGDNYUHGIMUDM-NHCUHLMSSA-N 50054091 (2R,3R)-2-Dipropylamino-3-phenyl-indan-5-ol::CHEMBL335515 D(2) dopamine receptor Rattus norvegicus 0.84 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054091&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10566865 103950749 CHEMBL335515 ZINC27425056 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778195 N[C@@H]1Cc2ccc(O)cc2[C@H]1c1ccccc1 InChI=1S/C15H15NO/c16-14-8-11-6-7-12(17)9-13(11)15(14)10-4-2-1-3-5-10/h1-7,9,14-15,17H,8,16H2/t14-,15-/m1/s1 FLDPVLFJZMQUDO-HUUCEWRRSA-N 50054089 (2R,3R)-2-Amino-3-phenyl-indan-5-ol::CHEMBL135224 D(2) dopamine receptor Rattus norvegicus 0.59 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054089&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10537185 103950747 CHEMBL135224 ZINC12355919 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778202 CCCN(CCC)[C@@H]1Cc2cc(O)ccc2[C@H]1c1ccccc1 InChI=1S/C21H27NO/c1-3-12-22(13-4-2)20-15-17-14-18(23)10-11-19(17)21(20)16-8-6-5-7-9-16/h5-11,14,20-21,23H,3-4,12-13,15H2,1-2H3/t20-,21-/m1/s1 UKBSEXXIPDXGCH-NHCUHLMSSA-N 50054090 (1R,2R)-2-Dipropylamino-1-phenyl-indan-5-ol::CHEMBL135735 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054090&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10638646 103950748 CHEMBL135735 ZINC27420078 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778204 C[C@@]1(N)Cc2cc(O)c(O)cc2[C@@]1(C)c1ccccc1 InChI=1S/C17H19NO2/c1-16(18)10-11-8-14(19)15(20)9-13(11)17(16,2)12-6-4-3-5-7-12/h3-9,19-20H,10,18H2,1-2H3/t16-,17-/m1/s1 HMBQZQRSXKUUEB-IAGOWNOFSA-N 50054093 (1R,2R)-2-Amino-1,2-dimethyl-1-phenyl-indan-5,6-diol::CHEMBL132766 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44356291 103950751 CHEMBL132766 ZINC27428152 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778209 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778212 CN(CC=C)[C@@H]1Cc2ccc(O)cc2[C@H]1c1ccccc1 InChI=1S/C19H21NO/c1-3-11-20(2)18-12-15-9-10-16(21)13-17(15)19(18)14-7-5-4-6-8-14/h3-10,13,18-19,21H,1,11-12H2,2H3/t18-,19-/m1/s1 XWQIFHFKVSCKAY-RTBURBONSA-N 50054084 (2R,3R)-2-(Allyl-methyl-amino)-3-phenyl-indan-5-ol::CHEMBL135197 D(2) dopamine receptor Rattus norvegicus 0.43 ChEMBL 10.1021/jm960318v 10.7270/Q2WQ04FD 8863801 Claudi, F; Cingolani, GM; Di Stefano, A; Giorgioni, G; Amenta, F; Barili, P; Ferrari, F; Giuliani, D Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054084&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10516818 103950742 CHEMBL135197 ZINC27425059 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778220 COc1ccc2CCCC(CCCN3CCCCC3)c2c1 InChI=1S/C19H29NO/c1-21-18-11-10-17-8-5-7-16(19(17)15-18)9-6-14-20-12-3-2-4-13-20/h10-11,15-16H,2-9,12-14H2,1H3 VPFKRKYVDOVZFI-UHFFFAOYSA-N 50054114 1-[3-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperidine::CHEMBL135738 D(2) dopamine receptor Rattus norvegicus >1850 ChEMBL 10.1021/jm9508898 10.7270/Q2RX9CRK 8863803 Berardi, F; Giudice, G; Perrone, R; Tortorella, V; Govoni, S; Lucchi, L Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054114&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10803229 103950764 CHEMBL135738 ZINC13759835 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778223 COc1cccc2C(CCCN3CCC(Cc4ccccc4)CC3)CCCc12 InChI=1S/C26H35NO/c1-28-26-14-6-12-24-23(10-5-13-25(24)26)11-7-17-27-18-15-22(16-19-27)20-21-8-3-2-4-9-21/h2-4,6,8-9,12,14,22-23H,5,7,10-11,13,15-20H2,1H3 WRFURAZNSFDBGH-UHFFFAOYSA-N 50054116 4-Benzyl-1-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperidine::CHEMBL134717 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm9508898 10.7270/Q2RX9CRK 8863803 Berardi, F; Giudice, G; Perrone, R; Tortorella, V; Govoni, S; Lucchi, L Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054116&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10595772 103950766 CHEMBL134717 ZINC13759829 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778224 COc1cccc2C(CCCN3CCCCC3)CCCc12 InChI=1S/C19H29NO/c1-21-19-12-6-10-17-16(8-5-11-18(17)19)9-7-15-20-13-3-2-4-14-20/h6,10,12,16H,2-5,7-9,11,13-15H2,1H3 OECXRJKGMSAVLR-UHFFFAOYSA-N 50054117 1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperidine::1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperidine::CHEMBL134607 D(2) dopamine receptor Rattus norvegicus >1850 ChEMBL 10.1021/jm9508898 10.7270/Q2RX9CRK 8863803 Berardi, F; Giudice, G; Perrone, R; Tortorella, V; Govoni, S; Lucchi, L Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054117&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10493545 103950767 CHEMBL134607 ZINC13759837 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778239 CC1(C)CCCN(CCCCC2CCCc3ccccc23)C1 InChI=1S/C21H33N/c1-21(2)14-8-16-22(17-21)15-6-5-10-19-12-7-11-18-9-3-4-13-20(18)19/h3-4,9,13,19H,5-8,10-12,14-17H2,1-2H3 JAJILYYYWBUWHZ-UHFFFAOYSA-N 50054121 3,3-Dimethyl-1-[4-(1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperidine::CHEMBL128442 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm9508898 10.7270/Q2RX9CRK 8863803 Berardi, F; Giudice, G; Perrone, R; Tortorella, V; Govoni, S; Lucchi, L Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10590294 103950771 CHEMBL128442 ZINC13759846 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778243 CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1 ZZJYIKPMDIWRSN-TZBSWOFLSA-N 50366495 (+)butaclamol::CHEMBL1255588 D(2) dopamine receptor Rattus norvegicus 0.30 ChEMBL 10.1021/jm9508898 10.7270/Q2RX9CRK 8863803 Berardi, F; Giudice, G; Perrone, R; Tortorella, V; Govoni, S; Lucchi, L Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37461 160845597 73298 CHEMBL1255588 ZINC01481744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50778244 COc1cccc2C(CCCN3CCCC(C)(C)C3)CCCc12 InChI=1S/C21H33NO/c1-21(2)13-7-15-22(16-21)14-6-9-17-8-4-11-19-18(17)10-5-12-20(19)23-3/h5,10,12,17H,4,6-9,11,13-16H2,1-3H3 XBELINVRDYBWOG-UHFFFAOYSA-N 50054124 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-3,3-dimethyl-piperidine::CHEMBL127006 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm9508898 10.7270/Q2RX9CRK 8863803 Berardi, F; Giudice, G; Perrone, R; Tortorella, V; Govoni, S; Lucchi, L Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054124&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10245193 103950774 CHEMBL127006 ZINC13759842 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783551 Oc1ccc2CC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m1/s1 DWUAAOIZQFTYQP-MRXNPFEDSA-N 50061669 (R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL134807::CHEMBL64553 D(2) dopamine receptor Rattus norvegicus 0.20 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378389 103957219 CHEMBL134807CHEMBL64553 ZINC13527706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783552 Oc1ccc2CCC(CNCc3cccc4ccccc34)Oc2c1 InChI=1S/C21H21NO2/c23-18-10-8-16-9-11-19(24-21(16)12-18)14-22-13-17-6-3-5-15-4-1-2-7-20(15)17/h1-8,10,12,19,22-23H,9,11,13-14H2 QLJKVRVRUHCBTI-UHFFFAOYSA-N 50061666 2-{[(Naphthalen-1-ylmethyl)-amino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL135242 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061666&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10567650 103957216 CHEMBL135242 ZINC13775962 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783553 Oc1ccc2CCC(CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2 DWUAAOIZQFTYQP-UHFFFAOYSA-N 50061684 2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL135395 D(2) dopamine receptor Rattus norvegicus 8.4 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061684&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22910005 103957234 CHEMBL135395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783555 Oc1cc2OC(CNCc3ccccc3)CCc2cc1Cl InChI=1S/C17H18ClNO2/c18-15-8-13-6-7-14(21-17(13)9-16(15)20)11-19-10-12-4-2-1-3-5-12/h1-5,8-9,14,19-20H,6-7,10-11H2 BCTPODDQZONFKA-UHFFFAOYSA-N 50061653 2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; oxalic acid::CHEMBL337228 D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061653&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9839426 103957203 CHEMBL337228 ZINC13775966 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783558 Oc1ccc2OC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C16H17NO3/c18-13-6-7-15-16(8-13)20-14(11-19-15)10-17-9-12-4-2-1-3-5-12/h1-8,14,17-18H,9-11H2/t14-/m0/s1 DYWYWIOQKKRAST-AWEZNQCLSA-N 50061642 (S)-3-(Benzylamino-methyl)-2,3-dihydro-benzo[1,4]dioxin-6-ol; oxalic acid::CHEMBL300571::CHEMBL423890 D(2) dopamine receptor Rattus norvegicus 5.7 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061642&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10612157 103957192 CHEMBL300571CHEMBL423890 ZINC13775979 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783559 CN1C[C@H](C[C@H]2[C@H]1Cc1c(C)[nH]c3cccc2c13)NC(=O)C(C)(C)C InChI=1S/C21H29N3O/c1-12-15-10-18-16(14-7-6-8-17(22-12)19(14)15)9-13(11-24(18)5)23-20(25)21(2,3)4/h6-8,13,16,18,22H,9-11H2,1-5H3,(H,23,25)/t13-,16+,18+/m0/s1 ZNMWUMGOSWLWOH-FDQGKXFDSA-N 50061687 CHEMBL336390::N-((6aR,9S,10aR)-5,7-Dimethyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-9-yl)-2,2-dimethyl-propionamide D(2) dopamine receptor Rattus norvegicus 1 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061687&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 148841 103957237 CHEMBL336390 ZINC03802834 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783560 CC(C)CCNCC1CCc2ccc(O)cc2O1 InChI=1S/C15H23NO2/c1-11(2)7-8-16-10-14-6-4-12-3-5-13(17)9-15(12)18-14/h3,5,9,11,14,16-17H,4,6-8,10H2,1-2H3 QUTOZVVXGBXVSP-UHFFFAOYSA-N 50061688 2-[(3-Methyl-butylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL134843 D(2) dopamine receptor Rattus norvegicus 36 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061688&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10634367 103957238 CHEMBL134843 ZINC03959256 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783564 COc1ccc2CCC(CNCCCOc3cccc(N)c3)Oc2c1 InChI=1S/C20H26N2O3/c1-23-17-8-6-15-7-9-19(25-20(15)13-17)14-22-10-3-11-24-18-5-2-4-16(21)12-18/h2,4-6,8,12-13,19,22H,3,7,9-11,14,21H2,1H3 TYIZMLIZHZSCOR-UHFFFAOYSA-N 50061686 3-{3-[(7-Methoxy-chroman-2-ylmethyl)-amino]-propoxy}-phenylamine; hydrochloride::CHEMBL541094 D(2) dopamine receptor Rattus norvegicus 222 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645499 103957236 CHEMBL541094 ZINC13775937 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783566 Oc1ccc2CCC(CNC3CCCCC3)Oc2c1 InChI=1S/C16H23NO2/c18-14-8-6-12-7-9-15(19-16(12)10-14)11-17-13-4-2-1-3-5-13/h6,8,10,13,15,17-18H,1-5,7,9,11H2 AFXVAXQMGUXVBX-UHFFFAOYSA-N 50061672 2-Cyclohexylaminomethyl-chroman-7-ol; oxalic acid::CHEMBL135011 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10563379 103957222 CHEMBL135011 ZINC13775954 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783568 Nc1cccc(OCCCNCC2CCc3ccccc3O2)c1 InChI=1S/C19H24N2O2/c20-16-6-3-7-17(13-16)22-12-4-11-21-14-18-10-9-15-5-1-2-8-19(15)23-18/h1-3,5-8,13,18,21H,4,9-12,14,20H2 LZDHUMNPJASCMA-UHFFFAOYSA-N 50061685 3-{3-[(Chroman-2-ylmethyl)-amino]-propoxy}-phenylamine; oxalic acid::CHEMBL134678 D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061685&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10543145 103957235 CHEMBL134678 ZINC12356087 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783573 Oc1ccc2CC[C@@H](CN3CCc4ccccc4C3)Oc2c1 InChI=1S/C19H21NO2/c21-17-7-5-15-6-8-18(22-19(15)11-17)13-20-10-9-14-3-1-2-4-16(14)12-20/h1-5,7,11,18,21H,6,8-10,12-13H2/t18-/m0/s1 IWUPLAFLTUWLMF-SFHVURJKSA-N 50061635 (S)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chroman-7-ol; oxalic acid::CHEMBL135725 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061635&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10803829 103957185 CHEMBL135725 ZINC12356066 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783574 Oc1ccc2CCC(CNCCCOc3ccc4cccnc4c3)Oc2c1 InChI=1S/C22H24N2O3/c25-18-7-4-17-6-9-20(27-22(17)13-18)15-23-10-2-12-26-19-8-5-16-3-1-11-24-21(16)14-19/h1,3-5,7-8,11,13-14,20,23,25H,2,6,9-10,12,15H2 CPMKULWZFNXOBS-UHFFFAOYSA-N 50061673 2-{[3-(Quinolin-7-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL135183 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061673&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10594944 103957223 CHEMBL135183 ZINC13775921 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783577 Oc1ccc(CNCC2CCc3ccc(O)cc3O2)cc1 InChI=1S/C17H19NO3/c19-14-5-1-12(2-6-14)10-18-11-16-8-4-13-3-7-15(20)9-17(13)21-16/h1-3,5-7,9,16,18-20H,4,8,10-11H2 COAJRUUAHDYFLT-UHFFFAOYSA-N 50061633 2-[(4-Hydroxy-benzylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL339190 D(2) dopamine receptor Rattus norvegicus 0.60 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061633&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10565066 103957183 CHEMBL339190 ZINC13775976 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783580 Oc1ccc2CC[C@@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m0/s1 DWUAAOIZQFTYQP-INIZCTEOSA-N 50061667 (S)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL138016 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061667&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10801925 103957217 CHEMBL138016 ZINC13775957 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783582 Nc1cccc(OCCCNCC2CCc3ccc(O)cc3O2)c1 InChI=1S/C19H24N2O3/c20-15-3-1-4-17(11-15)23-10-2-9-21-13-18-8-6-14-5-7-16(22)12-19(14)24-18/h1,3-5,7,11-12,18,21-22H,2,6,8-10,13,20H2 VEXJEWIAHBSEBB-UHFFFAOYSA-N 50061648 2-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-chroman-7-ol; hydrochloride::CHEMBL543426 D(2) dopamine receptor Rattus norvegicus 0.90 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10664055 103957198 CHEMBL543426 ZINC13775917 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783586 Oc1ccc2CC[C@H](CN3CCc4ccccc4C3)Oc2c1 InChI=1S/C19H21NO2/c21-17-7-5-15-6-8-18(22-19(15)11-17)13-20-10-9-14-3-1-2-4-16(14)12-20/h1-5,7,11,18,21H,6,8-10,12-13H2/t18-/m1/s1 IWUPLAFLTUWLMF-GOSISDBHSA-N 50061681 (R)-2-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-chroman-7-ol; oxalic acid::CHEMBL135044 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061681&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10803828 103957231 CHEMBL135044 ZINC12356067 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783587 Cc1c(N)cccc1OCCCNCC1CCc2ccc(O)cc2O1 InChI=1S/C20H26N2O3/c1-14-18(21)4-2-5-19(14)24-11-3-10-22-13-17-9-7-15-6-8-16(23)12-20(15)25-17/h2,4-6,8,12,17,22-23H,3,7,9-11,13,21H2,1H3 JMHOWYVJMKHOJR-UHFFFAOYSA-N 50061658 2-{[3-(3-Amino-2-methyl-phenoxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134605 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061658&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10783507 103957208 CHEMBL134605 ZINC13775925 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783589 Cc1noc2cc(OCCCNCC3CCc4ccc(O)cc4O3)ccc12 InChI=1S/C21H24N2O4/c1-14-19-8-7-17(12-21(19)27-23-14)25-10-2-9-22-13-18-6-4-15-3-5-16(24)11-20(15)26-18/h3,5,7-8,11-12,18,22,24H,2,4,6,9-10,13H2,1H3 OLYVLNMYFDULPJ-UHFFFAOYSA-N 50061646 2-{[3-(3-Methyl-benzo[d]isoxazol-6-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134930 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061646&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9799403 103957196 CHEMBL134930 ZINC13775933 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783590 Oc1ccc2CCC(CNCCCOc3cccc4[nH]ccc34)Oc2c1 InChI=1S/C21H24N2O3/c24-16-7-5-15-6-8-17(26-21(15)13-16)14-22-10-2-12-25-20-4-1-3-19-18(20)9-11-23-19/h1,3-5,7,9,11,13,17,22-24H,2,6,8,10,12,14H2 MSCOCRBMEUIKRL-UHFFFAOYSA-N 50061675 2-{[3-(1H-Indol-4-yloxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134707 D(2) dopamine receptor Rattus norvegicus 0.70 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061675&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10641733 103957225 CHEMBL134707 ZINC12356190 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783592 Nc1cccc(OCCCNCC2CCc3ccc(O)cc3C2)c1 InChI=1S/C20H26N2O2/c21-18-3-1-4-20(13-18)24-10-2-9-22-14-15-5-6-16-7-8-19(23)12-17(16)11-15/h1,3-4,7-8,12-13,15,22-23H,2,5-6,9-11,14,21H2 RUTCZVPJACQPHP-UHFFFAOYSA-N 50061647 7-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-5,6,7,8-tetrahydro-naphthalen-2-ol; oxalic acid::CHEMBL135864 D(2) dopamine receptor Rattus norvegicus 546 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10568152 103957197 CHEMBL135864 ZINC13775919 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783594 CS(=O)(=O)Nc1ccc2CCC(CNCCCO)Oc2c1 InChI=1S/C14H22N2O4S/c1-21(18,19)16-12-5-3-11-4-6-13(20-14(11)9-12)10-15-7-2-8-17/h3,5,9,13,15-17H,2,4,6-8,10H2,1H3 FONSKAIHCFLVMC-UHFFFAOYSA-N 50061683 CHEMBL135297::N-{2-[(3-Hydroxy-propylamino)-methyl]-chroman-7-yl}-methanesulfonamide; oxalic acid D(2) dopamine receptor Rattus norvegicus 662 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061683&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10591372 103957233 CHEMBL135297 ZINC13775945 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783595 Oc1ccc2CCC(CNCc3ccc(Cl)cc3)Oc2c1 InChI=1S/C17H18ClNO2/c18-14-5-1-12(2-6-14)10-19-11-16-8-4-13-3-7-15(20)9-17(13)21-16/h1-3,5-7,9,16,19-20H,4,8,10-11H2 QTGAERMWSORYGD-UHFFFAOYSA-N 50061665 2-[(4-Chloro-benzylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL135873 D(2) dopamine receptor Rattus norvegicus 0.30 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061665&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10518570 103957215 CHEMBL135873 ZINC13775974 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783597 C(NCc1ccccc1)C1CCc2ccccc2O1 InChI=1S/C17H19NO/c1-2-6-14(7-3-1)12-18-13-16-11-10-15-8-4-5-9-17(15)19-16/h1-9,16,18H,10-13H2 YGSXNPFZXQFLSH-UHFFFAOYSA-N 50061690 Benzyl-chroman-2-ylmethyl-amine; oxalic acid::CHEMBL134655 D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061690&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10753388 103957240 CHEMBL134655 ZINC12355975 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783598 CC(C)CNCC1CCc2ccc(O)cc2O1 InChI=1S/C14H21NO2/c1-10(2)8-15-9-13-6-4-11-3-5-12(16)7-14(11)17-13/h3,5,7,10,13,15-16H,4,6,8-9H2,1-2H3 SQAQEPLVGLAOHM-UHFFFAOYSA-N 50061637 2-(Isobutylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL135269 D(2) dopamine receptor Rattus norvegicus 7.9 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10633524 103957187 CHEMBL135269 ZINC13775950 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783609 Fc1ccc(CNCC2CCc3ccccc3O2)cc1 InChI=1S/C17H18FNO/c18-15-8-5-13(6-9-15)11-19-12-16-10-7-14-3-1-2-4-17(14)20-16/h1-6,8-9,16,19H,7,10-12H2 BUISWLRGGNVLQY-UHFFFAOYSA-N 50061677 CHEMBL135211::Chroman-2-ylmethyl-(4-fluoro-benzyl)-amine; oxalic acid D(2) dopamine receptor Rattus norvegicus 74 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061677&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10707255 103957227 CHEMBL135211 ZINC13775970 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783620 CN(CC1CCc2ccc(O)cc2O1)Cc1ccccc1 InChI=1S/C18H21NO2/c1-19(12-14-5-3-2-4-6-14)13-17-10-8-15-7-9-16(20)11-18(15)21-17/h2-7,9,11,17,20H,8,10,12-13H2,1H3 NSEJEWWJBYGEFK-UHFFFAOYSA-N 50061668 2-[(Benzyl-methyl-amino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL135291 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061668&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10755425 103957218 CHEMBL135291 ZINC13775968 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783622 Oc1cc2O[C@@H](CNCc3ccccc3)CCc2cc1Cl InChI=1S/C17H18ClNO2/c18-15-8-13-6-7-14(21-17(13)9-16(15)20)11-19-10-12-4-2-1-3-5-12/h1-5,8-9,14,19-20H,6-7,10-11H2/t14-/m1/s1 BCTPODDQZONFKA-CQSZACIVSA-N 50061640 (R)-2-(Benzylamino-methyl)-6-chloro-chroman-7-ol; oxalic acid::CHEMBL135357 D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061640&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10685891 103957190 CHEMBL135357 ZINC13775965 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783625 CS(=O)(=O)Nc1ccc2CCC(CNCCCOc3cccc(N)c3)Oc2c1 InChI=1S/C20H27N3O4S/c1-28(24,25)23-17-8-6-15-7-9-19(27-20(15)13-17)14-22-10-3-11-26-18-5-2-4-16(21)12-18/h2,4-6,8,12-13,19,22-23H,3,7,9-11,14,21H2,1H3 LJCATBRSEIHKGF-UHFFFAOYSA-N 50061634 CHEMBL133833::N-(2-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-chroman-7-yl)-methanesulfonamide; oxalic acid D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061634&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9844212 103957184 CHEMBL133833 ZINC13775939 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783626 Cc1ccc(OCCCNCC2CCc3ccc(O)cc3O2)cc1N InChI=1S/C20H26N2O3/c1-14-3-7-17(12-19(14)21)24-10-2-9-22-13-18-8-5-15-4-6-16(23)11-20(15)25-18/h3-4,6-7,11-12,18,22-23H,2,5,8-10,13,21H2,1H3 DTJUYOKAKLONJT-UHFFFAOYSA-N 50061655 2-{[3-(3-Amino-4-methyl-phenoxy)-propylamino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134281 D(2) dopamine receptor Rattus norvegicus 2.3 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061655&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10497505 103957205 CHEMBL134281 ZINC13775929 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783630 COc1ccc2CCC(CNCCCO)Oc2c1 InChI=1S/C14H21NO3/c1-17-12-5-3-11-4-6-13(18-14(11)9-12)10-15-7-2-8-16/h3,5,9,13,15-16H,2,4,6-8,10H2,1H3 CCFWRAKLQXVCPZ-UHFFFAOYSA-N 50061689 3-[(7-Methoxy-chroman-2-ylmethyl)-amino]-propan-1-ol; oxalic acid::CHEMBL133776 D(2) dopamine receptor Rattus norvegicus 20861 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061689&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10514903 103957239 CHEMBL133776 ZINC13775941 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783633 Nc1cccc(OCCCNC[C@@H]2COc3ccc(O)cc3O2)c1 InChI=1S/C18H22N2O4/c19-13-3-1-4-15(9-13)22-8-2-7-20-11-16-12-23-17-6-5-14(21)10-18(17)24-16/h1,3-6,9-10,16,20-21H,2,7-8,11-12,19H2/t16-/m1/s1 XQRSLRUXPXVCRY-MRXNPFEDSA-N 50061651 (R)-3-{[3-(3-Amino-phenoxy)-propylamino]-methyl}-2,3-dihydro-benzo[1,4]dioxin-6-ol::CHEMBL423335 D(2) dopamine receptor Rattus norvegicus 278 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44355732 103957201 CHEMBL423335 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783634 Oc1ccc2CCC(CNCc3ccco3)Oc2c1 InChI=1S/C15H17NO3/c17-12-5-3-11-4-6-14(19-15(11)8-12)10-16-9-13-2-1-7-18-13/h1-3,5,7-8,14,16-17H,4,6,9-10H2 VGDCLOXHDNBUQX-UHFFFAOYSA-N 50061678 2-{[(Furan-2-ylmethyl)-amino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL134582 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061678&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10515430 103957228 CHEMBL134582 ZINC12355978 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787559 CN1CCc2c([nH]c3ccccc23)C(C1)c1ccccc1 InChI=1S/C19H20N2/c1-21-12-11-16-15-9-5-6-10-18(15)20-19(16)17(13-21)14-7-3-2-4-8-14/h2-10,17,20H,11-13H2,1H3 MIBJALISUVUJMQ-UHFFFAOYSA-N 50067809 3-Methyl-5-phenyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indole::CHEMBL23529 D(2) dopamine receptor Rattus norvegicus 27200 ChEMBL 10.1021/jm980156y 10.7270/Q2708230 9804688 Efange, SM; Mash, DC; Khare, AB; Ouyang, Q University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333685 103962235 CHEMBL23529 ZINC12356001 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787560 CCN1CCc2c(sc3ccccc23)C(C1)c1ccc(Cl)c(Cl)c1 InChI=1S/C20H19Cl2NS/c1-2-23-10-9-15-14-5-3-4-6-19(14)24-20(15)16(12-23)13-7-8-17(21)18(22)11-13/h3-8,11,16H,2,9-10,12H2,1H3 UUABPOTWOAIFHX-UHFFFAOYSA-N 50067810 9-(3,4-Dichloro-phenyl)-7-ethyl-6,7,8,9-tetrahydro-5H-10-thia-7-aza-benzo[a]azulene::CHEMBL336437 D(2) dopamine receptor Rattus norvegicus 5000 ChEMBL 10.1021/jm980156y 10.7270/Q2708230 9804688 Efange, SM; Mash, DC; Khare, AB; Ouyang, Q University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10571551 103962236 CHEMBL336437 ZINC13781864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787563 CC[C@H]1C[C@H]2C[C@@H]3[C@H]1N(C2)CCc1c3[nH]c2ccc(OC)cc12 InChI=1S/C20H26N2O/c1-3-13-8-12-9-17-19-15(6-7-22(11-12)20(13)17)16-10-14(23-2)4-5-18(16)21-19/h4-5,10,12-13,17,20-21H,3,6-9,11H2,1-2H3/t12-,13-,17-,20-/m0/s1 HSIBGVUMFOSJPD-NXWOVTFFSA-N 50206577 10-methoxyibogamine::CHEMBL222287::IBOGAINE D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980156y 10.7270/Q2708230 9804688 Efange, SM; Mash, DC; Khare, AB; Ouyang, Q University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50206577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50206577&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 442108 104084576 CHEMBL222287 C09214 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765185 Cc1nc2sccn2c(=O)c1CCN1CCN(CC1)C1CC(c2cc(Cl)ccc12)c1ccc(F)cc1 InChI=1S/C28H28ClFN4OS/c1-18-22(27(35)34-14-15-36-28(34)31-18)8-9-32-10-12-33(13-11-32)26-17-24(19-2-5-21(30)6-3-19)25-16-20(29)4-7-23(25)26/h2-7,14-16,24,26H,8-13,17H2,1H3 BZFNKUVKRNSKNV-UHFFFAOYSA-N 50368652 CHEMBL1744123 D(2) dopamine receptor Rattus norvegicus 65 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368652&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44326431 160847754 CHEMBL1744123 ZINC26668704 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765187 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2ccccc2)C1=O InChI=1S/C27H35ClN4O/c1-20(2)32-17-16-31(27(32)33)15-12-29-10-13-30(14-11-29)26-19-24(21-6-4-3-5-7-21)25-18-22(28)8-9-23(25)26/h3-9,18,20,24,26H,10-17,19H2,1-2H3 CVLNVCXWAROBFP-UHFFFAOYSA-N 50368653 CHEMBL1744119 D(2) dopamine receptor Rattus norvegicus 750 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368653&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653127 160847755 CHEMBL1744119 ZINC26671156 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765188 Fc1ccc(cc1)C1CC(N2CCN(CCCN3CCNC3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C25H30ClFN4O/c26-19-4-7-21-23(16-19)22(18-2-5-20(27)6-3-18)17-24(21)30-14-12-29(13-15-30)9-1-10-31-11-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) VAEVQHTXJSLDAA-UHFFFAOYSA-N 50368654 CHEMBL1744125 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368654&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653119 160847756 CHEMBL1744125 ZINC26667172 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765194 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2ccc(C)cc2)C1=O InChI=1S/C28H37ClN4O/c1-20(2)33-17-16-32(28(33)34)15-12-30-10-13-31(14-11-30)27-19-25(22-6-4-21(3)5-7-22)26-18-23(29)8-9-24(26)27/h4-9,18,20,25,27H,10-17,19H2,1-3H3 JRIOFYBJCTZIOW-UHFFFAOYSA-N 50368658 CHEMBL1744108 D(2) dopamine receptor Rattus norvegicus 450 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368658&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653131 160847760 CHEMBL1744108 ZINC26669083 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765199 Fc1ccc(cc1)[C@@H]1C[C@@H](N2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H29FN4O/c25-19-7-5-18(6-8-19)22-17-23(21-4-2-1-3-20(21)22)28-14-11-27(12-15-28)13-16-29-10-9-26-24(29)30/h1-8,22-23H,9-17H2,(H,26,30)/t22-,23+/m0/s1 GHAMYXPEZSUOCU-XZOQPEGZSA-N 50020232 1-(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one(Irindalone)::CHEMBL73461::Irindalone D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020232&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65845 103931146 CHEMBL73461 ZINC22463226 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765204 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCNC3=S)CC2)c2ccc(F)cc12 InChI=1S/C24H28F2N4S/c25-18-3-1-17(2-4-18)21-16-23(20-6-5-19(26)15-22(20)21)29-12-9-28(10-13-29)11-14-30-8-7-27-24(30)31/h1-6,15,21,23H,7-14,16H2,(H,27,31) AVOSQJJHXGCJIZ-UHFFFAOYSA-N 50368659 CHEMBL1744112 D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368659&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037294 160847761 CHEMBL1744112 ZINC26661371 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765208 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2ccc(F)cc2)C1=O InChI=1S/C27H34ClFN4O/c1-19(2)33-16-15-32(27(33)34)14-11-30-9-12-31(13-10-30)26-18-24(20-3-6-22(29)7-4-20)25-17-21(28)5-8-23(25)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3 SDFCYOFNWWEZEI-UHFFFAOYSA-N 50368661 CHEMBL1744121 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368661&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9913230 160847763 CHEMBL1744121 ZINC22940772 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765209 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(ccc23)C(F)(F)F)c2ccc(F)cc2)C1=O InChI=1S/C28H34F4N4O/c1-19(2)36-16-15-35(27(36)37)14-11-33-9-12-34(13-10-33)26-18-24(20-3-6-22(29)7-4-20)25-17-21(28(30,31)32)5-8-23(25)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3 XDVMQRQYTNBNKW-UHFFFAOYSA-N 50368664 CHEMBL1744117 D(2) dopamine receptor Rattus norvegicus 510 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368664&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653124 160847766 CHEMBL1744117 ZINC26669896 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765210 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(Br)ccc23)c2ccc(F)cc2)C1=O InChI=1S/C27H34BrFN4O/c1-19(2)33-16-15-32(27(33)34)14-11-30-9-12-31(13-10-30)26-18-24(20-3-6-22(29)7-4-20)25-17-21(28)5-8-23(25)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3 JOAAFQMXBGOANP-UHFFFAOYSA-N 50368665 CHEMBL1744122 D(2) dopamine receptor Rattus norvegicus 240 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368665&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653123 160847767 CHEMBL1744122 ZINC26660409 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765216 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765218 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=S)CC2)c2ccc(F)cc12 InChI=1S/C25H30F2N4S/c26-19-4-2-18(3-5-19)22-17-24(21-7-6-20(27)16-23(21)22)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) PBFXTDGYIRQFSK-UHFFFAOYSA-N 50368656 CHEMBL1204307::CHEMBL1744111 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368656&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037269 160847758 CHEMBL1744111CHEMBL1204307 ZINC22940839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765219 Fc1ccc(cc1)C1CC(N2CCN(CCn3c4ccccc4[nH]c3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C28H28ClFN4O/c29-20-7-10-22-24(17-20)23(19-5-8-21(30)9-6-19)18-27(22)33-14-11-32(12-15-33)13-16-34-26-4-2-1-3-25(26)31-28(34)35/h1-10,17,23,27H,11-16,18H2,(H,31,35) WKQANGSPADPBMJ-UHFFFAOYSA-N 50368670 CHEMBL1744124 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368670&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653120 160847772 CHEMBL1744124 ZINC26667158 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765224 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(C)ccc23)c2ccc(F)cc2)C1=O InChI=1S/C28H37FN4O/c1-20(2)33-17-16-32(28(33)34)15-12-30-10-13-31(14-11-30)27-19-25(22-5-7-23(29)8-6-22)26-18-21(3)4-9-24(26)27/h4-9,18,20,25,27H,10-17,19H2,1-3H3 RYLUFOUUBWPVCW-UHFFFAOYSA-N 50368673 CHEMBL1744115 D(2) dopamine receptor Rattus norvegicus 450 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368673&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653125 160847775 CHEMBL1744115 ZINC26659080 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765227 Cc1ccc2C(CC(c2c1)c1ccc(F)cc1)N1CCN(CCO)CC1 InChI=1S/C22H27FN2O/c1-16-2-7-19-21(14-16)20(17-3-5-18(23)6-4-17)15-22(19)25-10-8-24(9-11-25)12-13-26/h2-7,14,20,22,26H,8-13,15H2,1H3 BZBHGCBFWKSYCV-UHFFFAOYSA-N 50368674 CHEMBL1744118 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368674&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44326342 160847776 CHEMBL1744118 ZINC26669911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765228 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=O)CC2)c2ccc(F)cc12 InChI=1S/C25H30F2N4O/c26-19-4-2-18(3-5-19)22-17-24(21-7-6-20(27)16-23(21)22)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) PZHUDBDNTWZLRQ-UHFFFAOYSA-N 50368675 CHEMBL1744113 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368675&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037273 160847777 CHEMBL1744113 ZINC26660913 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766911 CCCN1CC[C@@H]2Cc3c(C[C@@H]12)cccc3OC InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m1/s1 HDCVYYTWHHFQGS-UKRRQHHQSA-N 50034324 (3aS,9aR) 5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::(3aS,9aR)-5-methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11388 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377224 103942525 CHEMBL11388 ZINC13826563 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766912 COc1cccc2C[C@@H]3NCC[C@@H]3Cc12 InChI=1S/C13H17NO/c1-15-13-4-2-3-9-8-12-10(5-6-14-12)7-11(9)13/h2-4,10,12,14H,5-8H2,1H3/t10-,12+/m1/s1 OBGADVDRELNMHY-PWSUYJOCSA-N 50034314 (3aS,9aS)-5-Methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::5-Methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL12108 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10262307 103942515 CHEMBL12108 ZINC13826555 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766915 CCCN1CC[C@H]2Cc3c(C[C@H]12)cccc3OC InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15-/m0/s1 HDCVYYTWHHFQGS-ZFWWWQNUSA-N 50040184 (3aR,9aS)-5-methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL267559 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040184 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040184&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377225 103972244 CHEMBL267559 ZINC13826561 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766922 Oc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12 InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m1/s1 GNOHLPXINNYCLR-TZMCWYRMSA-N 50034346 (3aS,9aR) 1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(3aS,9aR)-1-allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL11363 D(2) dopamine receptor Rattus norvegicus 47.0 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014057 103942547 CHEMBL11363 ZINC13826580 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766930 COc1cccc2C[C@H]3CCN(CC=C)[C@@H]3Cc12 InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-12-5-4-6-16(18-2)14(12)11-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1 RRAWYIITFCQESJ-UKRRQHHQSA-N 50034353 (3aS,9aR)-1-Allyl-8-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::1-Allyl-8-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11770 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034353&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377136 103942554 CHEMBL11770 ZINC13826588 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766933 COc1cccc2C[C@@H]3[C@H](CCN3CC=C)Cc12 InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m1/s1 ASEDQXVCNPLEIO-UKRRQHHQSA-N 50034350 (3aS,9aR) 1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::(3aS,9aR)-1-allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11170 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037437 103942551 CHEMBL11170 ZINC13826569 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766935 COc1cccc2C[C@H]3[C@H](CCN3CC=C)Cc12 InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m1/s1 ASEDQXVCNPLEIO-HIFRSBDPSA-N 50034345 (3aS,9aS)-1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11294 D(2) dopamine receptor Rattus norvegicus 429 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10014674 103942546 CHEMBL11294 ZINC13826549 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766939 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766940 COc1cccc2C[C@H]3[C@@H](CCN3CC=C)Cc12 InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h3-6,13,15H,1,7-11H2,2H3/t13-,15-/m0/s1 ASEDQXVCNPLEIO-ZFWWWQNUSA-N 50040185 (3aR,9aS)-1-allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::1-Allyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL275008 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040185 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040185&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10243514 103972245 CHEMBL275008 ZINC13826567 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766942 COc1cccc2C[C@H]3[C@H](CCN3CC3CC3)Cc12 InChI=1S/C17H23NO/c1-19-17-4-2-3-13-10-16-14(9-15(13)17)7-8-18(16)11-12-5-6-12/h2-4,12,14,16H,5-11H2,1H3/t14-,16+/m1/s1 ZZPRPPYBWAPLEI-ZBFHGGJFSA-N 50034343 (3aS,9aS)-1-Cyclopropylmethyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::1-Cyclopropylmethyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL273601 D(2) dopamine receptor Rattus norvegicus 748 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264456 103942544 CHEMBL273601 ZINC13826557 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766944 CCCN1CC[C@@H]2Cc3c(C[C@H]12)cccc3OC InChI=1S/C16H23NO/c1-3-8-17-9-7-13-10-14-12(11-15(13)17)5-4-6-16(14)18-2/h4-6,13,15H,3,7-11H2,1-2H3/t13-,15+/m1/s1 HDCVYYTWHHFQGS-HIFRSBDPSA-N 50034320 (3aS,9aS)-5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::5-Methoxy-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11381 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105934 103942521 CHEMBL11381 ZINC13826547 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766947 Oc1cccc2C[C@@H]3[C@H](CCN3CC3CC3)Cc12 InChI=1S/C16H21NO/c18-16-3-1-2-12-9-15-13(8-14(12)16)6-7-17(15)10-11-4-5-11/h1-3,11,13,15,18H,4-10H2/t13-,15-/m1/s1 IOHQVZZQVYGLGG-UKRRQHHQSA-N 50034338 (3aS,9aR)-1-Cyclopropylmethyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Cyclopropylmethyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL11771 D(2) dopamine receptor Rattus norvegicus 118 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10444473 103942539 CHEMBL11771 ZINC12355950 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766948 Oc1cccc2C[C@H]3[C@@H](CCN3CC=C)Cc12 InChI=1S/C15H19NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h2-5,12,14,17H,1,6-10H2/t12-,14-/m0/s1 GNOHLPXINNYCLR-JSGCOSHPSA-N 50040183 (3aR,9aS)-1-allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Allyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL267557 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040183 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040183&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10398936 103972243 CHEMBL267557 ZINC13826578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766949 CCCN1CC[C@H]2Cc3c(O)cccc3C[C@H]12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m0/s1 DYVLYWKEJHHXOH-JSGCOSHPSA-N 50040182 (3aR,9aS)-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL11065 D(2) dopamine receptor Rattus norvegicus >630 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040182&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10036887 103972242 CHEMBL11065 ZINC13826573 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766950 CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@@H]12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14-/m1/s1 DYVLYWKEJHHXOH-TZMCWYRMSA-N 50034352 (3aS,9aR) 1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::(3aS,9aR)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL11066 D(2) dopamine receptor Rattus norvegicus 17.0 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105311 103942553 CHEMBL11066 ZINC13826575 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766951 CCCN1CC[C@@H]2Cc3c(O)cccc3C[C@H]12 InChI=1S/C15H21NO/c1-2-7-16-8-6-12-9-13-11(10-14(12)16)4-3-5-15(13)17/h3-5,12,14,17H,2,6-10H2,1H3/t12-,14+/m1/s1 DYVLYWKEJHHXOH-OCCSQVGLSA-N 50034319 (3aS,9aS)-1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::1-Propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indol-5-ol::CHEMBL275689 D(2) dopamine receptor Rattus norvegicus 296 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11776081 103942520 CHEMBL275689 ZINC13826553 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766952 CCCN1[C@@H](C)C[C@@H]2Cc3cccc(OC)c3C[C@H]12 InChI=1S/C17H25NO/c1-4-8-18-12(2)9-14-10-13-6-5-7-17(19-3)15(13)11-16(14)18/h5-7,12,14,16H,4,8-11H2,1-3H3/t12-,14+,16-/m0/s1 XIQFFWZUFKJVOP-BJJXKVORSA-N 50034323 (2 beta-methyl) 8-Methoxy-2-methyl-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::(2S,3aS,9aS)-8-Methoxy-2-methyl-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::8-Methoxy-2-methyl-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11386 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10355219 103942524 CHEMBL11386 ZINC13826592 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766956 COc1cccc2C[C@@H]3[C@H](CCN3CC3CC3)Cc12 InChI=1S/C17H23NO/c1-19-17-4-2-3-13-10-16-14(9-15(13)17)7-8-18(16)11-12-5-6-12/h2-4,12,14,16H,5-11H2,1H3/t14-,16-/m1/s1 ZZPRPPYBWAPLEI-GDBMZVCRSA-N 50034347 (3aS,9aR)-1-(cyclopropylmethyl)-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::(3aS,9aR)-1-Cyclopropylmethyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::1-Cyclopropylmethyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL267769 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10445202 103942548 CHEMBL267769 ZINC13826586 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766958 COc1cccc2C[C@@H]3[C@H](CCN3Cc3ccccc3)Cc12 InChI=1S/C20H23NO/c1-22-20-9-5-8-16-13-19-17(12-18(16)20)10-11-21(19)14-15-6-3-2-4-7-15/h2-9,17,19H,10-14H2,1H3/t17-,19-/m1/s1 SRCYZESDHGJOSG-IEBWSBKVSA-N 50034361 (3aS,9aR)-1-Benzyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::1-Benzyl-5-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11880 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034361&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10447116 103942562 CHEMBL11880 ZINC13826571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766963 CCCN1[C@H](C)C[C@@H]2Cc3cccc(OC)c3C[C@H]12 InChI=1S/C17H25NO/c1-4-8-18-12(2)9-14-10-13-6-5-7-17(19-3)15(13)11-16(14)18/h5-7,12,14,16H,4,8-11H2,1-3H3/t12-,14-,16+/m1/s1 XIQFFWZUFKJVOP-XPKDYRNWSA-N 50034325 (2 alpha-methyl) 8-Methoxy-2-methyl-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::(2R,3aS,9aS)-8-Methoxy-2-methyl-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::8-Methoxy-2-methyl-1-propyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11387 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10400362 103942526 CHEMBL11387 ZINC13826590 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50766968 COc1cccc2C[C@H]3CCN(CC=C)[C@H]3Cc12 InChI=1S/C16H21NO/c1-3-8-17-9-7-13-10-12-5-4-6-16(18-2)14(12)11-15(13)17/h3-6,13,15H,1,7-11H2,2H3/t13-,15+/m1/s1 RRAWYIITFCQESJ-HIFRSBDPSA-N 50034344 (3aS,9aS)-1-Allyl-8-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::1-Allyl-8-methoxy-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]indole::CHEMBL11365 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00060a015 10.7270/Q2833SPR 8097538 Lin, CH; Haadsma-Svensson, SR; Phillips, G; Lahti, RA; McCall, RB; Piercey, MF; Schreur, PJ; Von Voigtlander, PF; Smith, MW; Chidester, CG Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10444472 103942545 CHEMBL11365 ZINC13826559 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783637 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783638 Oc1ccc2CCC(CNCc3ccncc3)Oc2c1 InChI=1S/C16H18N2O2/c19-14-3-1-13-2-4-15(20-16(13)9-14)11-18-10-12-5-7-17-8-6-12/h1,3,5-9,15,18-19H,2,4,10-11H2 CMPVSRKCPJUIRW-UHFFFAOYSA-N 50061680 2-{[(Pyridin-4-ylmethyl)-amino]-methyl}-chroman-7-ol; oxalic acid::CHEMBL135285 D(2) dopamine receptor Rattus norvegicus 115 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10221090 103957230 CHEMBL135285 ZINC04632551 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783648 Nc1nc2CCN(CC=C)CCc2s1 InChI=1S/C10H15N3S/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8/h2H,1,3-7H2,(H2,11,12) DHSSDEDRBUKTQY-UHFFFAOYSA-N 86053 B-HT 920::CAS_101626-70-4::CHEMBL279085::NSC_104870::Talipexole::cid_5374 D(2) dopamine receptor Rattus norvegicus 5.8 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5374 136352153 CHEMBL279085 ZINC00006644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783652 CS(=O)(=O)Nc1ccc2CCC(CNCc3ccccc3)Oc2c1 InChI=1S/C18H22N2O3S/c1-24(21,22)20-16-9-7-15-8-10-17(23-18(15)11-16)13-19-12-14-5-3-2-4-6-14/h2-7,9,11,17,19-20H,8,10,12-13H2,1H3 LOXIOAISACXTLR-UHFFFAOYSA-N 50061664 CHEMBL337696::N-[2-(Benzylamino-methyl)-chroman-7-yl]-methanesulfonamide; oxalic acid D(2) dopamine receptor Rattus norvegicus 8.8 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061664&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593705 103957214 CHEMBL337696 ZINC13775964 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50783659 Oc1ccc2CCC(CNCCCc3ccccc3)Oc2c1 InChI=1S/C19H23NO2/c21-17-10-8-16-9-11-18(22-19(16)13-17)14-20-12-4-7-15-5-2-1-3-6-15/h1-3,5-6,8,10,13,18,20-21H,4,7,9,11-12,14H2 UFPFTPPWVXLEQS-UHFFFAOYSA-N 50061661 2-[(3-Phenyl-propylamino)-methyl]-chroman-7-ol; oxalic acid::CHEMBL135495 D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm9703653 10.7270/Q2KP82TD 9435894 Mewshaw, RE; Kavanagh, J; Stack, G; Marquis, KL; Shi, X; Kagan, MZ; Webb, MB; Katz, AH; Park, A; Kang, YH; Abou-Gharbia, M; Scerni, R; Wasik, T; Cortes-Burgos, L; Spangler, T; Brennan, JA; Piesla, M; Mazandarani, H; Cockett, MI; Ochalski, R; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061661&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10590126 103957211 CHEMBL135495 ZINC12356077 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787581 CCN1CCc2c(sc3ccccc23)C(C1)c1ccccc1 InChI=1S/C20H21NS/c1-2-21-13-12-17-16-10-6-7-11-19(16)22-20(17)18(14-21)15-8-4-3-5-9-15/h3-11,18H,2,12-14H2,1H3 QSIVEZLJXIOJFH-UHFFFAOYSA-N 50067811 7-Ethyl-9-phenyl-6,7,8,9-tetrahydro-5H-10-thia-7-aza-benzo[a]azulene::CHEMBL141863 D(2) dopamine receptor Rattus norvegicus 5000 ChEMBL 10.1021/jm980156y 10.7270/Q2708230 9804688 Efange, SM; Mash, DC; Khare, AB; Ouyang, Q University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9861399 103962237 CHEMBL141863 ZINC13781858 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787585 CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(Br)c1 InChI=1S/C20H20BrNS/c1-2-22-11-10-17-16-8-3-4-9-19(16)23-20(17)18(13-22)14-6-5-7-15(21)12-14/h3-9,12,18H,2,10-11,13H2,1H3 AZJLNNJMUCJPAO-UHFFFAOYSA-N 50067816 9-(3-Bromo-phenyl)-7-ethyl-6,7,8,9-tetrahydro-5H-10-thia-7-aza-benzo[a]azulene::CHEMBL139081 D(2) dopamine receptor Rattus norvegicus 3500 ChEMBL 10.1021/jm980156y 10.7270/Q2708230 9804688 Efange, SM; Mash, DC; Khare, AB; Ouyang, Q University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11794523 103962242 CHEMBL139081 ZINC13781860 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787594 CCN1CCc2c(sc3ccccc23)C(C1)c1cccc(c1)[N+]([O-])=O InChI=1S/C20H20N2O2S/c1-2-21-11-10-17-16-8-3-4-9-19(16)25-20(17)18(13-21)14-6-5-7-15(12-14)22(23)24/h3-9,12,18H,2,10-11,13H2,1H3 KUJMJVJTQWVBSI-UHFFFAOYSA-N 50067815 7-Ethyl-9-(3-nitro-phenyl)-6,7,8,9-tetrahydro-5H-10-thia-7-aza-benzo[a]azulene::CHEMBL341805 D(2) dopamine receptor Rattus norvegicus 3100 ChEMBL 10.1021/jm980156y 10.7270/Q2708230 9804688 Efange, SM; Mash, DC; Khare, AB; Ouyang, Q University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10712993 103962241 CHEMBL341805 ZINC13781862 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787604 CC[C@@H]1CC2C[C@H]3C1N(C2)CCc1c3[nH]c2ccc(O)cc12 InChI=1S/C19H24N2O/c1-2-12-7-11-8-16-18-14(5-6-21(10-11)19(12)16)15-9-13(22)3-4-17(15)20-18/h3-4,9,11-12,16,19-20,22H,2,5-8,10H2,1H3/t11?,12-,16-,19?/m1/s1 RAUCDOKTMDOIPF-NYRFGNLRSA-N 50067814 17-ethyl-(1R,17S)-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraen-7-ol (noribogaine)::CHEMBL343956 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm980156y 10.7270/Q2708230 9804688 Efange, SM; Mash, DC; Khare, AB; Ouyang, Q University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44359441 103962240 CHEMBL343956 ZINC27519780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765231 OCCN1CCN(CC1)C1CC(c2cc(F)ccc12)c1ccc(F)cc1 InChI=1S/C21H24F2N2O/c22-16-3-1-15(2-4-16)19-14-21(18-6-5-17(23)13-20(18)19)25-9-7-24(8-10-25)11-12-26/h1-6,13,19,21,26H,7-12,14H2 XISRGFHXAPVIRZ-UHFFFAOYSA-N 50045614 2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL1204306::CHEMBL320684 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154792 103976490 CHEMBL320684CHEMBL1204306 ZINC22940744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765233 CCN1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2ccc(F)cc2)C1=O InChI=1S/C26H32ClFN4O/c1-2-30-15-16-32(26(30)33)14-11-29-9-12-31(13-10-29)25-18-23(19-3-6-21(28)7-4-19)24-17-20(27)5-8-22(24)25/h3-8,17,23,25H,2,9-16,18H2,1H3 SFPIUNVSVANBEJ-UHFFFAOYSA-N 50368678 CHEMBL1744120 D(2) dopamine receptor Rattus norvegicus 260 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368678&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653114 160847780 CHEMBL1744120 ZINC26667669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765241 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2cccc(F)c2)C1=O InChI=1S/C27H34ClFN4O/c1-19(2)33-15-14-32(27(33)34)13-10-30-8-11-31(12-9-30)26-18-24(20-4-3-5-22(29)16-20)25-17-21(28)6-7-23(25)26/h3-7,16-17,19,24,26H,8-15,18H2,1-2H3 ZCEXQVGRWXYTLW-UHFFFAOYSA-N 50368677 CHEMBL1744106 D(2) dopamine receptor Rattus norvegicus 490 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368677&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653129 160847779 CHEMBL1744106 ZINC26661163 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765246 CSc1ccc2C(CC(c2c1)c1ccc(F)cc1)N1CCN(CCN2CCN(C(C)C)C2=O)CC1 InChI=1S/C28H37FN4OS/c1-20(2)33-17-16-32(28(33)34)15-12-30-10-13-31(14-11-30)27-19-25(21-4-6-22(29)7-5-21)26-18-23(35-3)8-9-24(26)27/h4-9,18,20,25,27H,10-17,19H2,1-3H3 AYQDRJYOATYGDZ-UHFFFAOYSA-N 50045616 1-(2-{4-[3-(4-Fluoro-phenyl)-5-methylsulfanyl-indan-1-yl]-piperazin-1-yl}-ethyl)-3-isopropyl-imidazolidin-2-one::CHEMBL92408 D(2) dopamine receptor Rattus norvegicus 720 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045616&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653126 103976492 CHEMBL92408 ZINC26660081 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765249 OCCN1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2ccc(F)cc2)C1=O InChI=1S/C26H32ClFN4O2/c27-20-3-6-22-24(17-20)23(19-1-4-21(28)5-2-19)18-25(22)30-10-7-29(8-11-30)9-12-31-13-14-32(15-16-33)26(31)34/h1-6,17,23,25,33H,7-16,18H2 YIZGWMMUCQTBCT-UHFFFAOYSA-N 50368655 CHEMBL1744128 D(2) dopamine receptor Rattus norvegicus 320 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368655&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653115 160847757 CHEMBL1744128 ZINC26667602 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765252 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2ccc(Cl)cc2)C1=O InChI=1S/C27H34Cl2N4O/c1-19(2)33-16-15-32(27(33)34)14-11-30-9-12-31(13-10-30)26-18-24(20-3-5-21(28)6-4-20)25-17-22(29)7-8-23(25)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3 MNGBFDADKNTDGN-UHFFFAOYSA-N 50368663 CHEMBL1744105 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368663&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653130 160847765 CHEMBL1744105 ZINC26662783 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765255 CN1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2ccc(F)cc2)C1=O InChI=1S/C25H30ClFN4O/c1-28-8-12-31(25(28)32)15-11-29-9-13-30(14-10-29)24-17-22(18-2-5-20(27)6-3-18)23-16-19(26)4-7-21(23)24/h2-7,16,22,24H,8-15,17H2,1H3 WJBHURQUCWQCQY-UHFFFAOYSA-N 50368679 CHEMBL1744109 D(2) dopamine receptor Rattus norvegicus 190 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653113 160847781 CHEMBL1744109 ZINC26670363 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765257 OCCN1CCN(CC1)C1CC(c2cc(ccc12)C(F)(F)F)c1ccc(F)cc1 InChI=1S/C22H24F4N2O/c23-17-4-1-15(2-5-17)19-14-21(28-9-7-27(8-10-28)11-12-29)18-6-3-16(13-20(18)19)22(24,25)26/h1-6,13,19,21,29H,7-12,14H2 SBIYOKBEEKCRRW-UHFFFAOYSA-N 50368666 CHEMBL1744116 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368666&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037289 160847768 CHEMBL1744116 ZINC26659631 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765261 Cl.Cl.Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCC3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C25H29ClFN3O.2ClH/c26-19-5-8-21-23(16-19)22(18-3-6-20(27)7-4-18)17-24(21)29-13-10-28(11-14-29)12-15-30-9-1-2-25(30)31;;/h3-8,16,22,24H,1-2,9-15,17H2;2*1H HLACQUMPUMJETO-UHFFFAOYSA-N 50045618 1-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-pyrrolidin-2-one dihydrochloride::CHEMBL2447982 D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73352655 103976494 CHEMBL2447982 ZINC26670832 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765263 OCCN1CCN(CC1)C1CC(c2ccc(Cl)cc12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2O/c22-16-3-6-18-19(15-1-4-17(23)5-2-15)14-21(20(18)13-16)25-9-7-24(8-10-25)11-12-26/h1-6,13,19,21,26H,7-12,14H2 WVMPJMHWCBRDFH-UHFFFAOYSA-N 50026960 (trans) 2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol; Dihydrochloride::2-{4-[6-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL422067 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10478809 103936544 CHEMBL422067 ZINC22937822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765266 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCN(C3=O)c3ccccc3)CC2)c2ccc(Cl)cc12 InChI=1S/C30H32ClFN4O/c31-23-8-11-26-28(20-23)27(22-6-9-24(32)10-7-22)21-29(26)34-15-12-33(13-16-34)14-17-35-18-19-36(30(35)37)25-4-2-1-3-5-25/h1-11,20,27,29H,12-19,21H2 IYXNMOCEVXJKKO-UHFFFAOYSA-N 50368672 CHEMBL1744127 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653116 160847774 CHEMBL1744127 ZINC26668423 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765267 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2ccccc2F)C1=O InChI=1S/C27H34ClFN4O/c1-19(2)33-16-15-32(27(33)34)14-11-30-9-12-31(13-10-30)26-18-24(21-5-3-4-6-25(21)29)23-17-20(28)7-8-22(23)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3 ZUXJOYPLVRUXPM-UHFFFAOYSA-N 50368671 CHEMBL1744110 D(2) dopamine receptor Rattus norvegicus 920 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368671&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653128 160847773 CHEMBL1744110 ZINC26670220 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765270 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C25H30ClFN4O/c26-19-4-7-21-23(16-19)22(18-2-5-20(27)6-3-18)17-24(21)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) HSNXEFAUYFXJAP-UHFFFAOYSA-N 50368657 CHEMBL1744114 D(2) dopamine receptor Rattus norvegicus 1700 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368657&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037281 160847759 CHEMBL1744114 ZINC26661609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765271 OCCN1CCN(CC1)C1CC(c2c1cccc2Cl)c1ccc(F)cc1 InChI=1S/C21H24ClFN2O/c22-19-3-1-2-17-20(25-10-8-24(9-11-25)12-13-26)14-18(21(17)19)15-4-6-16(23)7-5-15/h1-7,18,20,26H,8-14H2 ADWYWJGQPNBBNY-UHFFFAOYSA-N 50029391 2-{4-[4-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL92896 D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029391&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653098 103938461 CHEMBL92896 ZINC22937793 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765272 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCNC3=S)CC2)c2ccc(Cl)cc12 InChI=1S/C24H28ClFN4S/c25-18-3-6-20-22(15-18)21(17-1-4-19(26)5-2-17)16-23(20)29-12-9-28(10-13-29)11-14-30-8-7-27-24(30)31/h1-6,15,21,23H,7-14,16H2,(H,27,31) UXQFVDJWFYKEOK-UHFFFAOYSA-N 50368662 CHEMBL1744107 D(2) dopamine receptor Rattus norvegicus 67 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368662&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037286 160847764 CHEMBL1744107 ZINC26669068 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765274 OCCN1CCN(CC1)C1CC(c2cccc(Cl)c12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2O/c22-19-3-1-2-17-18(15-4-6-16(23)7-5-15)14-20(21(17)19)25-10-8-24(9-11-25)12-13-26/h1-7,18,20,26H,8-14H2 HKWOIXRWXXYROZ-UHFFFAOYSA-N 50029402 2-{4-[7-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::2-{4-[7-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol dimaleate::CHEMBL1788129::CHEMBL96618 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029402&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653096 103938472 CHEMBL1788129CHEMBL96618 ZINC22937835 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765275 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCNC3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C24H28ClFN4O/c25-18-3-6-20-22(15-18)21(17-1-4-19(26)5-2-17)16-23(20)29-12-9-28(10-13-29)11-14-30-8-7-27-24(30)31/h1-6,15,21,23H,7-14,16H2,(H,27,31) SUHGCSTVQXPTOC-UHFFFAOYSA-N 50045630 1-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL96571 D(2) dopamine receptor Rattus norvegicus 360 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045630&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15653112 103976506 CHEMBL96571 ZINC26667588 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765279 Fc1ccc(cc1)C1CC(N2CCN(CCn3c(=O)[nH]c4ccccc4c3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C29H28ClFN4O2/c30-20-7-10-22-25(17-20)24(19-5-8-21(31)9-6-19)18-27(22)34-14-11-33(12-15-34)13-16-35-28(36)23-3-1-2-4-26(23)32-29(35)37/h1-10,17,24,27H,11-16,18H2,(H,32,37) OEZDKSAWBIOPBE-UHFFFAOYSA-N 50368667 CHEMBL1744126 D(2) dopamine receptor Rattus norvegicus 93 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368667&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44326451 160847769 CHEMBL1744126 ZINC26661793 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769228 C#CCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C15H16N2/c1-2-8-17-9-4-7-15(12-17)14-6-3-5-13(10-14)11-16/h1,3,5-6,10,15H,4,7-9,12H2/t15-/m1/s1 WIXVSIWFYYDDMJ-OAHLLOKOSA-N 50039745 3-((S)-1-Prop-2-ynyl-piperidin-3-yl)-benzonitrile::CHEMBL91228 D(2) dopamine receptor Rattus norvegicus >15000 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039745&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9991216 103946940 CHEMBL91228 ZINC13738276 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769233 CCN1CCC[C@H](C1)c1cccc(OS(=O)(=O)C(F)(F)F)c1 InChI=1S/C14H18F3NO3S/c1-2-18-8-4-6-12(10-18)11-5-3-7-13(9-11)21-22(19,20)14(15,16)17/h3,5,7,9,12H,2,4,6,8,10H2,1H3/t12-/m1/s1 JMGZFNUKIOOZSN-GFCCVEGCSA-N 50039743 CHEMBL329139::Trifluoro-methanesulfonic acid 3-((S)-1-ethyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 1180 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039743&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10382430 103946938 CHEMBL329139 ZINC36187792 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769234 CCCN1CCC[C@H](C1)c1cccc(CO)c1 InChI=1S/C15H23NO/c1-2-8-16-9-4-7-15(11-16)14-6-3-5-13(10-14)12-17/h3,5-6,10,15,17H,2,4,7-9,11-12H2,1H3/t15-/m1/s1 BOTMSPLRFWVABA-OAHLLOKOSA-N 50039744 CHEMBL93101::[3-((S)-1-Propyl-piperidin-3-yl)-phenyl]-methanol D(2) dopamine receptor Rattus norvegicus 410 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039744&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10263410 103946939 CHEMBL93101 ZINC13738262 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769236 CCCN1CCC[C@H](C1)c1cccc(c1)S(=O)(=O)N(C)C InChI=1S/C16H26N2O2S/c1-4-10-18-11-6-8-15(13-18)14-7-5-9-16(12-14)21(19,20)17(2)3/h5,7,9,12,15H,4,6,8,10-11,13H2,1-3H3/t15-/m1/s1 KXDIYSZQVVAYOA-OAHLLOKOSA-N 50039738 CHEMBL329443::N,N-Dimethyl-3-((S)-1-propyl-piperidin-3-yl)-benzenesulfonamide D(2) dopamine receptor Rattus norvegicus 3390 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039738&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10018300 103946933 CHEMBL329443 ZINC13738267 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769237 CCCN1CCC[C@H](C1)c1cccc(OS(C)(=O)=O)c1 InChI=1S/C15H23NO3S/c1-3-9-16-10-5-7-14(12-16)13-6-4-8-15(11-13)19-20(2,17)18/h4,6,8,11,14H,3,5,7,9-10,12H2,1-2H3/t14-/m1/s1 AHSLTJCTFBJCMT-CQSZACIVSA-N 50039747 CHEMBL93594::Methanesulfonic acid 3-((S)-1-propyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 4170 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039747&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10402381 103946942 CHEMBL93594 ZINC13738259 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769251 N#Cc1cccc(c1)[C@@H]1CCCNC1 InChI=1S/C12H14N2/c13-8-10-3-1-4-11(7-10)12-5-2-6-14-9-12/h1,3-4,7,12,14H,2,5-6,9H2/t12-/m1/s1 RDRGDNFLGKTNOF-GFCCVEGCSA-N 50039756 (S)-3-Piperidin-3-yl-benzonitrile::CHEMBL93682 D(2) dopamine receptor Rattus norvegicus 2670 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039756&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10397550 103946951 CHEMBL93682 ZINC03785172 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769254 CCCN1CCC[C@H](C1)c1cccc(OCC(F)(F)F)c1 InChI=1S/C16H22F3NO/c1-2-8-20-9-4-6-14(11-20)13-5-3-7-15(10-13)21-12-16(17,18)19/h3,5,7,10,14H,2,4,6,8-9,11-12H2,1H3/t14-/m1/s1 RMFLBNXQMNGIHR-CQSZACIVSA-N 50039748 (S)-1-Propyl-3-[3-(2,2,2-trifluoro-ethoxy)-phenyl]-piperidine::CHEMBL93946 D(2) dopamine receptor Rattus norvegicus 1670 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039748&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10380129 103946943 CHEMBL93946 ZINC13738258 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769257 CCCN1CCC[C@H](C1)c1cccc(OS(=O)(=O)C(F)(F)F)c1 InChI=1S/C15H20F3NO3S/c1-2-8-19-9-4-6-13(11-19)12-5-3-7-14(10-12)22-23(20,21)15(16,17)18/h3,5,7,10,13H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 VUEGBGWRCATKQZ-CYBMUJFWSA-N 50039760 (-)-Trifluoro-methanesulfonic acid 3-(1-propyl-piperidin-3-yl)-phenyl ester::CHEMBL90359::Trifluoro-methanesulfonic acid 3-((S)-1-propyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 408 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039760&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654433 103946955 CHEMBL90359 ZINC36187784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769258 C=CCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C15H18N2/c1-2-8-17-9-4-7-15(12-17)14-6-3-5-13(10-14)11-16/h2-3,5-6,10,15H,1,4,7-9,12H2/t15-/m1/s1 LWSMSVQQKULODQ-OAHLLOKOSA-N 50039739 3-((S)-1-Allyl-piperidin-3-yl)-benzonitrile::CHEMBL93212 D(2) dopamine receptor Rattus norvegicus 1890 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039739&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10242819 103946934 CHEMBL93212 ZINC03785169 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769259 CCCN1CCC2C1CCc1c(OS(=O)(=O)C(F)(F)F)cccc21 InChI=1S/C16H20F3NO3S/c1-2-9-20-10-8-12-11-4-3-5-15(13(11)6-7-14(12)20)23-24(21,22)16(17,18)19/h3-5,12,14H,2,6-10H2,1H3 ASMVKSNPCVNVFO-UHFFFAOYSA-N 50039757 CHEMBL92682::Trifluoro-methanesulfonic acid 3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-yl ester D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039757&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325578 103946952 CHEMBL92682 ZINC36187790 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769268 CCCN1CCC[C@H](C1)c1cccc(c1)C(N)=O InChI=1S/C15H22N2O/c1-2-8-17-9-4-7-14(11-17)12-5-3-6-13(10-12)15(16)18/h3,5-6,10,14H,2,4,7-9,11H2,1H3,(H2,16,18)/t14-/m1/s1 CJCQHAUDAPOVBD-CQSZACIVSA-N 50039761 3-((S)-1-Propyl-piperidin-3-yl)-benzamide::CHEMBL92232 D(2) dopamine receptor Rattus norvegicus >15000 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039761 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039761&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10467118 103946956 CHEMBL92232 ZINC13738263 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769270 CCCN1CCC[C@H](C1)c1cccc(CC#N)c1 InChI=1S/C16H22N2/c1-2-10-18-11-4-7-16(13-18)15-6-3-5-14(12-15)8-9-17/h3,5-6,12,16H,2,4,7-8,10-11,13H2,1H3/t16-/m1/s1 RURTXDUFVIOALE-MRXNPFEDSA-N 50039741 CHEMBL93917::[3-((S)-1-Propyl-piperidin-3-yl)-phenyl]-acetonitrile D(2) dopamine receptor Rattus norvegicus 1229 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039741&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466922 103946936 CHEMBL93917 ZINC13738269 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769273 CCCN1CCC[C@H](C1)c1cccc(c1)C(C)=O InChI=1S/C16H23NO/c1-3-9-17-10-5-8-16(12-17)15-7-4-6-14(11-15)13(2)18/h4,6-7,11,16H,3,5,8-10,12H2,1-2H3/t16-/m1/s1 BBRKEERFZOYHTK-MRXNPFEDSA-N 50039764 1-[3-((S)-1-Propyl-piperidin-3-yl)-phenyl]-ethanone::CHEMBL90797 D(2) dopamine receptor Rattus norvegicus 6540 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039764 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039764&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377227 103946959 CHEMBL90797 ZINC13738272 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769276 N#Cc1cccc(c1)[C@@H]1CCCN(CCc2ccccc2)C1 InChI=1S/C20H22N2/c21-15-18-8-4-9-19(14-18)20-10-5-12-22(16-20)13-11-17-6-2-1-3-7-17/h1-4,6-9,14,20H,5,10-13,16H2/t20-/m1/s1 BARYHSADJVEXIX-HXUWFJFHSA-N 50039751 3-((S)-1-Phenethyl-piperidin-3-yl)-benzonitrile::CHEMBL93646 D(2) dopamine receptor Rattus norvegicus 105 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039751&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10334422 103946946 CHEMBL93646 ZINC13738279 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769287 CCCN1CCC[C@H](C1)c1cccc(OS(=O)(=O)c2ccc(C)cc2)c1 InChI=1S/C21H27NO3S/c1-3-13-22-14-5-7-19(16-22)18-6-4-8-20(15-18)25-26(23,24)21-11-9-17(2)10-12-21/h4,6,8-12,15,19H,3,5,7,13-14,16H2,1-2H3/t19-/m1/s1 HFJQAHIKNXSVRM-LJQANCHMSA-N 50039767 CHEMBL92630::Toluene-4-sulfonic acid 3-((S)-1-propyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 1320 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039767 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039767&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10384736 103946962 CHEMBL92630 ZINC13738260 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769288 CCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C14H18N2/c1-2-16-8-4-7-14(11-16)13-6-3-5-12(9-13)10-15/h3,5-6,9,14H,2,4,7-8,11H2,1H3/t14-/m1/s1 OPZKYIOCNPKDBN-CQSZACIVSA-N 50039758 3-((S)-1-Ethyl-piperidin-3-yl)-benzonitrile::CHEMBL90798 D(2) dopamine receptor Rattus norvegicus 2330 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039758 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039758&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10353207 103946953 CHEMBL90798 ZINC13738275 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769306 CCCN1CCC[C@H](C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 HTSNFXAICLXZMA-CYBMUJFWSA-N 50010617 (-)-3-(1-Propyl-piperidin-3-yl)-phenol::(S)-3-(1-propylpiperidin-3-yl)phenol::3-((S)-1-Propyl-piperidin-3-yl)-phenol::3-(1-Propyl-piperidin-3-yl)-phenol::3PPP,(+)::CHEMBL7549::Preclamol D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010617&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311189 103923391 CHEMBL7549 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769310 NC(=O)c1cccc2C3CCN(CC=C)C3CCc12 InChI=1S/C16H20N2O/c1-2-9-18-10-8-13-11-4-3-5-14(16(17)19)12(11)6-7-15(13)18/h2-5,13,15H,1,6-10H2,(H2,17,19) ITRJBWXLLLCDGV-UHFFFAOYSA-N 50039771 3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-6-carboxylic acid amide::CHEMBL96726 D(2) dopamine receptor Rattus norvegicus >172 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039771&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325900 103946966 CHEMBL96726 ZINC40461387 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769323 FC(F)(F)S(=O)(=O)Oc1cccc(c1)[C@@H]1CCCN(CCc2ccccc2)C1 InChI=1S/C20H22F3NO3S/c21-20(22,23)28(25,26)27-19-10-4-8-17(14-19)18-9-5-12-24(15-18)13-11-16-6-2-1-3-7-16/h1-4,6-8,10,14,18H,5,9,11-13,15H2/t18-/m1/s1 GHZCAYNGRYIDPW-GOSISDBHSA-N 50039736 CHEMBL328119::Trifluoro-methanesulfonic acid 3-((S)-1-phenethyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039736&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10251160 103946931 CHEMBL328119 ZINC36216529 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769331 CCC(C)N1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C16H22N2/c1-3-13(2)18-9-5-8-16(12-18)15-7-4-6-14(10-15)11-17/h4,6-7,10,13,16H,3,5,8-9,12H2,1-2H3/t13?,16-/m1/s1 TYYIXERJKMDZBL-FQNRMIAFSA-N 50039778 3-((S)-1-sec-Butyl-piperidin-3-yl)-benzonitrile::CHEMBL413483 D(2) dopamine receptor Rattus norvegicus 1050 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039778 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039778&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10466923 103946973 CHEMBL413483 ZINC13738278 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769333 CCCN1CCC[C@H](C1)c1ccccc1 InChI=1S/C14H21N/c1-2-10-15-11-6-9-14(12-15)13-7-4-3-5-8-13/h3-5,7-8,14H,2,6,9-12H2,1H3/t14-/m1/s1 BJGOULYFYANDMK-CQSZACIVSA-N 50039755 (S)-3-Phenyl-1-propyl-piperidine::CHEMBL315890 D(2) dopamine receptor Rattus norvegicus 1490 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039755 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039755&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10330528 103946950 CHEMBL315890 ZINC13492912 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769335 CN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C13H16N2/c1-15-7-3-6-13(10-15)12-5-2-4-11(8-12)9-14/h2,4-5,8,13H,3,6-7,10H2,1H3/t13-/m1/s1 WTTCSLJBJDWDOC-CYBMUJFWSA-N 50039766 3-((S)-1-Methyl-piperidin-3-yl)-benzonitrile::CHEMBL90662 D(2) dopamine receptor Rattus norvegicus 8330 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10330427 103946961 CHEMBL90662 ZINC13738274 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769336 CCc1sccc1N1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C18H20N2S/c1-2-18-17(8-10-21-18)20-9-4-7-16(13-20)15-6-3-5-14(11-15)12-19/h3,5-6,8,10-11,16H,2,4,7,9,13H2,1H3/t16-/m1/s1 FLHNFXPLCFJIDJ-MRXNPFEDSA-N 50039763 3-[(S)-1-(2-Ethyl-thiophen-3-yl)-piperidin-3-yl]-benzonitrile::CHEMBL93570 D(2) dopamine receptor Rattus norvegicus 102 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039763 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039763&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325908 103946958 CHEMBL93570 ZINC26658470 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769341 FC(F)(F)S(=O)(=O)Oc1cccc2C3CCN(CC=C)C3CCc12 InChI=1S/C16H18F3NO3S/c1-2-9-20-10-8-12-11-4-3-5-15(13(11)6-7-14(12)20)23-24(21,22)16(17,18)19/h2-5,12,14H,1,6-10H2 JNAGEIMWCSOQKU-UHFFFAOYSA-N 50039750 CHEMBL93534::Trifluoro-methanesulfonic acid 3-allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-yl ester D(2) dopamine receptor Rattus norvegicus >172 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039750&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325577 103946945 CHEMBL93534 ZINC36187788 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769343 N#Cc1cccc(c1)[C@@H]1CCCN(CC2CC2)C1 InChI=1S/C16H20N2/c17-10-14-3-1-4-15(9-14)16-5-2-8-18(12-16)11-13-6-7-13/h1,3-4,9,13,16H,2,5-8,11-12H2/t16-/m1/s1 RWFSSGIYTQCWMB-MRXNPFEDSA-N 50039772 3-((S)-1-Cyclopropylmethyl-piperidin-3-yl)-benzonitrile::CHEMBL328894 D(2) dopamine receptor Rattus norvegicus 3100 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039772&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10037311 103946967 CHEMBL328894 ZINC12355935 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769348 CCCN1CCC[C@H](C1)c1ccc(OS(=O)(=O)C(F)(F)F)cc1 InChI=1S/C15H20F3NO3S/c1-2-9-19-10-3-4-13(11-19)12-5-7-14(8-6-12)22-23(20,21)15(16,17)18/h5-8,13H,2-4,9-11H2,1H3/t13-/m1/s1 QBBNRIPQRWMMNR-CYBMUJFWSA-N 50039779 CHEMBL328448::Trifluoro-methanesulfonic acid 4-((S)-1-propyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 11800 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039779&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10405678 103946974 CHEMBL328448 ZINC36216526 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769354 CCCN1CCC[C@H](C1)c1ccccc1OS(=O)(=O)C(F)(F)F InChI=1S/C15H20F3NO3S/c1-2-9-19-10-5-6-12(11-19)13-7-3-4-8-14(13)22-23(20,21)15(16,17)18/h3-4,7-8,12H,2,5-6,9-11H2,1H3/t12-/m1/s1 IQMKIUFAVWKRQY-GFCCVEGCSA-N 50039776 CHEMBL93701::Trifluoro-methanesulfonic acid 2-((S)-1-propyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 92 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039776 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039776&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10450580 103946971 CHEMBL93701 ZINC36187786 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769359 CCCN1CCC[C@H](C1)c1cccc(c1)S(C)(=O)=O InChI=1S/C15H23NO2S/c1-3-9-16-10-5-7-14(12-16)13-6-4-8-15(11-13)19(2,17)18/h4,6,8,11,14H,3,5,7,9-10,12H2,1-2H3/t14-/m1/s1 GZVBVBMMNFIXGE-CQSZACIVSA-N 50039749 (S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidine::(S)-3-(3-Methanesulfonyl-phenyl)-1-propyl-piperidine::CHEMBL311730 D(2) dopamine receptor Rattus norvegicus 6270 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039749&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9795741 103946944 CHEMBL311730 ZINC03811315 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769362 CN(C)CCCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C17H25N3/c1-19(2)9-5-11-20-10-4-8-17(14-20)16-7-3-6-15(12-16)13-18/h3,6-7,12,17H,4-5,8-11,14H2,1-2H3/t17-/m1/s1 AKBLTSXPRUVMOS-QGZVFWFLSA-N 50039754 3-[(S)-1-(3-Dimethylamino-propyl)-piperidin-3-yl]-benzonitrile::CHEMBL327836 D(2) dopamine receptor Rattus norvegicus 2330 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039754&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10084584 103946949 CHEMBL327836 ZINC13738281 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769363 CCCN1CCC[C@H](C1)c1cccc(c1)C#C InChI=1S/C16H21N/c1-3-10-17-11-6-9-16(13-17)15-8-5-7-14(4-2)12-15/h2,5,7-8,12,16H,3,6,9-11,13H2,1H3/t16-/m1/s1 PGAXGWGBGVJKJG-MRXNPFEDSA-N 50039777 (S)-3-(3-Ethynyl-phenyl)-1-propyl-piperidine::CHEMBL93283 D(2) dopamine receptor Rattus norvegicus 709 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039777 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039777&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10242850 103946972 CHEMBL93283 ZINC13738270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769365 N#Cc1cccc(c1)[C@@H]1CCCN(CCCc2ccccc2)C1 InChI=1S/C21H24N2/c22-16-19-9-4-11-20(15-19)21-12-6-14-23(17-21)13-5-10-18-7-2-1-3-8-18/h1-4,7-9,11,15,21H,5-6,10,12-14,17H2/t21-/m1/s1 JSFVESKREDQPEC-OAQYLSRUSA-N 50039735 3-[(S)-1-(3-Phenyl-propyl)-piperidin-3-yl]-benzonitrile::CHEMBL94811 D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039735&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086395 103946930 CHEMBL94811 ZINC13738280 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769366 CCCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C15H20N2/c1-2-8-17-9-4-7-15(12-17)14-6-3-5-13(10-14)11-16/h3,5-6,10,15H,2,4,7-9,12H2,1H3/t15-/m1/s1 GQRIAOUUYRIMLH-OAHLLOKOSA-N 50039769 3-((S)-1-Propyl-piperidin-3-yl)-benzonitrile::CHEMBL92183 D(2) dopamine receptor Rattus norvegicus 1140 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039769 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039769&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816005 103946964 CHEMBL92183 ZINC03785159 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769375 CN1CCC[C@H](C1)c1cccc(OS(=O)(=O)C(F)(F)F)c1 InChI=1S/C13H16F3NO3S/c1-17-7-3-5-11(9-17)10-4-2-6-12(8-10)20-21(18,19)13(14,15)16/h2,4,6,8,11H,3,5,7,9H2,1H3/t11-/m1/s1 FNUIZCKBCPUNIM-LLVKDONJSA-N 50039782 CHEMBL94224::Trifluoro-methanesulfonic acid 3-((S)-1-methyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 11800 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11723696 103946977 CHEMBL94224 ZINC36187785 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769378 C=CCN1CCC2C1CCc1c(cccc21)C#N InChI=1S/C16H18N2/c1-2-9-18-10-8-15-14-5-3-4-12(11-17)13(14)6-7-16(15)18/h2-5,15-16H,1,6-10H2 ZOXQOLDAOFYVMZ-UHFFFAOYSA-N 50039762 3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-6-carbonitrile::CHEMBL92939 D(2) dopamine receptor Rattus norvegicus >172 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039762 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039762&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325894 103946957 CHEMBL92939 ZINC26665598 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769379 CCCN1CCC[C@H](C1)c1cccc(C)c1 InChI=1S/C15H23N/c1-3-9-16-10-5-8-15(12-16)14-7-4-6-13(2)11-14/h4,6-7,11,15H,3,5,8-10,12H2,1-2H3/t15-/m1/s1 MMNXTTQJJITNJJ-OAHLLOKOSA-N 50039752 (S)-1-Propyl-3-m-tolyl-piperidine::CHEMBL93234 D(2) dopamine receptor Rattus norvegicus 930 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039752&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10420915 103946947 CHEMBL93234 ZINC13492908 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769381 CCCN1CCC[C@H](C1)c1cccc(C=O)c1 InChI=1S/C15H21NO/c1-2-8-16-9-4-7-15(11-16)14-6-3-5-13(10-14)12-17/h3,5-6,10,12,15H,2,4,7-9,11H2,1H3/t15-/m1/s1 UQOWIEJFNPPPBP-OAHLLOKOSA-N 50039781 3-((S)-1-Propyl-piperidin-3-yl)-benzaldehyde::CHEMBL92578 D(2) dopamine receptor Rattus norvegicus 1120 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039781&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9991512 103946976 CHEMBL92578 ZINC13738268 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792433 COc1ccccc1N1CCN(CCNC(=O)C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 InChI=1S/C24H35N3O2/c1-29-22-5-3-2-4-21(22)27-10-8-26(9-11-27)7-6-25-23(28)24-15-18-12-19(16-24)14-20(13-18)17-24/h2-5,18-20H,6-17H2,1H3,(H,25,28)/t18-,19+,20-,24? UMZYBCYFDMPPNO-GUHGBLDKSA-N 50083277 Adamantane-1-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide; Dihydrochloride::CHEMBL539818 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10250209 103982976 CHEMBL539818 ZINC53023082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792435 Clc1cccc(c1)N1CCN(CCNC(=O)C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 InChI=1S/C23H32ClN3O/c24-20-2-1-3-21(13-20)27-8-6-26(7-9-27)5-4-25-22(28)23-14-17-10-18(15-23)12-19(11-17)16-23/h1-3,13,17-19H,4-12,14-16H2,(H,25,28)/t17-,18+,19-,23? PMWKIVSTVWIKHW-NWKQVAMWSA-N 50083278 Adamantane-1-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide; Dihydrochloride::CHEMBL553497 D(2) dopamine receptor Rattus norvegicus 129 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10644772 103982977 CHEMBL553497 ZINC13802789 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792439 O=C(N[C@@H](CN1CCN(Cc2ccccc2)CC1)Cc1ccccc1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C31H41N3O/c35-30(31-19-26-15-27(20-31)17-28(16-26)21-31)32-29(18-24-7-3-1-4-8-24)23-34-13-11-33(12-14-34)22-25-9-5-2-6-10-25/h1-10,26-29H,11-23H2,(H,32,35)/t26-,27+,28-,29-,31?/m1/s1 FPCGZBYCAHIMKC-MGDUNCDCSA-N 50083284 Adamantane-1-carboxylic acid [1-benzyl-2-(4-benzyl-piperazin-1-yl)-ethyl]-amide; Dihydrochloride::CHEMBL541345 D(2) dopamine receptor Rattus norvegicus 1402 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083284&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9894526 103982983 CHEMBL541345 ZINC22939471 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792441 O=C(NCCN1CCN(CC1)c1ncccn1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C21H31N5O/c27-19(21-13-16-10-17(14-21)12-18(11-16)15-21)22-4-5-25-6-8-26(9-7-25)20-23-2-1-3-24-20/h1-3,16-18H,4-15H2,(H,22,27)/t16-,17+,18-,21? HPFLVTSWRFCPCV-IVRKQUHDSA-N 50083287 Adamantane-1-carboxylic acid [2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl]-amide; Dihydrochloride::CHEMBL545793 D(2) dopamine receptor Rattus norvegicus 166 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130918 103982986 CHEMBL545793 ZINC53046001 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792442 COc1ccccc1N1CCN(CCCNC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 InChI=1S/C25H38N4O2/c1-31-23-6-3-2-5-22(23)29-11-9-28(10-12-29)8-4-7-26-24(30)27-25-16-19-13-20(17-25)15-21(14-19)18-25/h2-3,5-6,19-21H,4,7-18H2,1H3,(H2,26,27,30)/t19-,20+,21-,25? HTZQCKIHMRMSJH-OVZPOALRSA-N 50083286 1-Adamantan-1-yl-3-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-urea; Dihydrochloride::CHEMBL538791 D(2) dopamine receptor Rattus norvegicus 176 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10764920 103982985 CHEMBL538791 ZINC13802823 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792450 O=C(N[C@H](CN1CCN(Cc2ccccc2)CC1)Cc1ccccc1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C31H41N3O/c35-30(31-19-26-15-27(20-31)17-28(16-26)21-31)32-29(18-24-7-3-1-4-8-24)23-34-13-11-33(12-14-34)22-25-9-5-2-6-10-25/h1-10,26-29H,11-23H2,(H,32,35)/t26-,27+,28-,29?,31? FPCGZBYCAHIMKC-BBANXYNDSA-N 50083288 Adamantane-1-carboxylic acid [1-benzyl-2-(4-benzyl-piperazin-1-yl)-ethyl]-amide; Dihydrochloride::CHEMBL545096 D(2) dopamine receptor Rattus norvegicus 3394 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083288&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9894528 103982987 CHEMBL545096 ZINC22939474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792454 COc1ccccc1N1CCN(CCOC(=O)C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 InChI=1S/C24H34N2O3/c1-28-22-5-3-2-4-21(22)26-8-6-25(7-9-26)10-11-29-23(27)24-15-18-12-19(16-24)14-20(13-18)17-24/h2-5,18-20H,6-17H2,1H3/t18-,19+,20-,24? BPSSGQHWKWKLTE-GUHGBLDKSA-N 50083268 Adamantane-1-carboxylic acid 2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl ester; Dihydrochloride::CHEMBL542983 D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083268&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795179 103982967 CHEMBL542983 ZINC13802785 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792462 COc1ccccc1N1CCN(CCC(=O)NC23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 InChI=1S/C24H35N3O2/c1-29-22-5-3-2-4-21(22)27-10-8-26(9-11-27)7-6-23(28)25-24-15-18-12-19(16-24)14-20(13-18)17-24/h2-5,18-20H,6-17H2,1H3,(H,25,28)/t18-,19+,20-,24? BUNRSIAHLPGQRT-GUHGBLDKSA-N 50083296 CHEMBL554204::N-Adamantan-1-yl-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propionamide; Dihydrochloride D(2) dopamine receptor Rattus norvegicus 93 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083296&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9930706 103982995 CHEMBL554204 ZINC03781326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792479 O=C(N[C@H](COCc1ccccc1)CN1CCN(Cc2ccccc2)CC1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C32H43N3O2/c36-31(32-18-27-15-28(19-32)17-29(16-27)20-32)33-30(24-37-23-26-9-5-2-6-10-26)22-35-13-11-34(12-14-35)21-25-7-3-1-4-8-25/h1-10,27-30H,11-24H2,(H,33,36)/t27-,28+,29-,30-,32?/m0/s1 UCTUSCULLMPPTK-WSSHCXSVSA-N 50083303 Adamantane-1-carboxylic acid [1-benzyloxymethyl-2-(4-benzyl-piperazin-1-yl)-ethyl]-amide; Dihydrochloride::CHEMBL539052 D(2) dopamine receptor Rattus norvegicus 76 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083303&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10348101 103983002 CHEMBL539052 ZINC27556809 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792482 C[C@H](CN1CCN(CC1)c1ncccn1)NC(=O)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C22H33N5O/c1-16(15-26-5-7-27(8-6-26)21-23-3-2-4-24-21)25-20(28)22-12-17-9-18(13-22)11-19(10-17)14-22/h2-4,16-19H,5-15H2,1H3,(H,25,28)/t16-,17-,18+,19-,22?/m1/s1 VZUHPBSTYDQEJX-XDIMERGTSA-N 50083291 Adamantane-1-carboxylic acid [(R)-1-methyl-2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl]-amide::CHEMBL356575 D(2) dopamine receptor Rattus norvegicus 153 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083291&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10596147 103982990 CHEMBL356575 ZINC13802799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792483 O=C(N[C@@H](CN1CCN(CC1)c1ncccn1)Cc1ccccc1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C28H37N5O/c34-26(28-17-22-13-23(18-28)15-24(14-22)19-28)31-25(16-21-5-2-1-3-6-21)20-32-9-11-33(12-10-32)27-29-7-4-8-30-27/h1-8,22-25H,9-20H2,(H,31,34)/t22-,23+,24-,25-,28?/m1/s1 DSJKVFVLCHZWFJ-JPJGLUIESA-N 50083300 Adamantane-1-carboxylic acid [(R)-1-benzyl-2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl]-amide::CHEMBL146343 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083300&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9854449 103982999 CHEMBL146343 ZINC13802804 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792494 COc1ccccc1N1CCN(CCCOC(=O)C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 InChI=1S/C25H36N2O3/c1-29-23-6-3-2-5-22(23)27-10-8-26(9-11-27)7-4-12-30-24(28)25-16-19-13-20(17-25)15-21(14-19)18-25/h2-3,5-6,19-21H,4,7-18H2,1H3/t19-,20+,21-,25? LNAYHHXHHRSQIP-OVZPOALRSA-N 50083271 Adamantane-1-carboxylic acid 3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl ester; Dihydrochloride::CHEMBL545562 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083271&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10621636 103982970 CHEMBL545562 ZINC13802787 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792501 O=C(NCCCN1CCN(CC1)c1ncccn1)NC12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C22H34N6O/c29-21(26-22-14-17-11-18(15-22)13-19(12-17)16-22)25-5-2-6-27-7-9-28(10-8-27)20-23-3-1-4-24-20/h1,3-4,17-19H,2,5-16H2,(H2,25,26,29)/t17-,18+,19-,22? RBIVLMIFOYIRGH-VTIBSLLJSA-N 50083299 1-Adamantan-1-yl-3-[3-(4-pyrimidin-2-yl-piperazin-1-yl)-propyl]-urea; Dihydrochloride::CHEMBL542508 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10572963 103982998 CHEMBL542508 ZINC13802822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792502 COc1ccccc1N1CCN(C[C@@H](C)NC(=O)C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 InChI=1S/C25H37N3O2/c1-18(26-24(29)25-14-19-11-20(15-25)13-21(12-19)16-25)17-27-7-9-28(10-8-27)22-5-3-4-6-23(22)30-2/h3-6,18-21H,7-17H2,1-2H3,(H,26,29)/t18-,19-,20+,21-,25?/m1/s1 ZJZSRDZIENVXMD-UAEIGRNHSA-N 50083280 Adamantane-1-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-1-methyl-ethyl}-amide; Dihydrochloride::CHEMBL543932 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10787793 103982979 CHEMBL543932 ZINC13802801 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792503 COc1ccccc1N1CCN(CCCNC(=O)C23C[C@H]4C[C@H](C[C@H](C4)C2)C3)CC1 InChI=1S/C25H37N3O2/c1-30-23-6-3-2-5-22(23)28-11-9-27(10-12-28)8-4-7-26-24(29)25-16-19-13-20(17-25)15-21(14-19)18-25/h2-3,5-6,19-21H,4,7-18H2,1H3,(H,26,29)/t19-,20+,21-,25? AZLBYNLKNFZXFQ-OVZPOALRSA-N 50083283 Adamantane-1-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide; hydrochloride::CHEMBL543692 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9844517 103982982 CHEMBL543692 ZINC03798943 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792504 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 119 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792508 O=C(OCCN1CCN(CC1)c1ncccn1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C21H30N4O2/c26-19(21-13-16-10-17(14-21)12-18(11-16)15-21)27-9-8-24-4-6-25(7-5-24)20-22-2-1-3-23-20/h1-3,16-18H,4-15H2/t16-,17+,18-,21? OUQDABCGMQSKTI-IVRKQUHDSA-N 50083272 Adamantane-1-carboxylic acid 2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl ester; Dihydrochloride::CHEMBL540865 D(2) dopamine receptor Rattus norvegicus 708 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083272&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10690544 103982971 CHEMBL540865 ZINC12356204 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50792515 O=C(N[C@H](CN1CCN(CC1)c1ncccn1)Cc1ccccc1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C28H37N5O/c34-26(28-17-22-13-23(18-28)15-24(14-22)19-28)31-25(16-21-5-2-1-3-6-21)20-32-9-11-33(12-10-32)27-29-7-4-8-30-27/h1-8,22-25H,9-20H2,(H,31,34)/t22-,23+,24-,25?,28? DSJKVFVLCHZWFJ-SXPBZBIBSA-N 50083309 Adamantane-1-carboxylic acid [(S)-1-benzyl-2-(4-pyrimidin-2-yl-piperazin-1-yl)-ethyl]-amide::CHEMBL148617 D(2) dopamine receptor Rattus norvegicus 1693 ChEMBL 10.1021/jm9806704 10.7270/Q2C82B0P 10602693 Abou-Gharbia, MA; Childers, WE; Fletcher, H; McGaughey, G; Patel, U; Webb, MB; Yardley, J; Andree, T; Boast, C; Kucharik, RJ; Marquis, K; Morris, H; Scerni, R; Moyer, JA Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083309&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9933918 103983008 CHEMBL148617 ZINC13802806 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765625 CCCNC1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 InChI=1S/C14H18F3NO3S/c1-2-8-18-11-7-6-10-4-3-5-13(12(10)9-11)21-22(19,20)14(15,16)17/h3-5,11,18H,2,6-9H2,1H3 ZRWGXXAMGVLDQT-UHFFFAOYSA-N 50034368 CHEMBL28313::Trifluoro-methanesulfonic acid 7-propylamino-5,6,7,8-tetrahydro-naphthalen-1-yl ester D(2) dopamine receptor Rattus norvegicus 1360 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034368 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034368&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14977566 103942569 CHEMBL28313 ZINC36187757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765626 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765627 CCCN(CCC)C1CCc2cccc(OC)c2C1 InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-10-9-14-7-6-8-17(19-3)16(14)13-15/h6-8,15H,4-5,9-13H2,1-3H3 SPOMVKJPPZWHRF-UHFFFAOYSA-N 50016737 (8-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL11760 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 193381 103928106 CHEMBL11760 ZINC03650260 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765632 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 1357 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765636 CCCN(CCC)C1CCc2c(C1)cccc2OC InChI=1S/C17H27NO/c1-4-11-18(12-5-2)15-9-10-16-14(13-15)7-6-8-17(16)19-3/h6-8,15H,4-5,9-13H2,1-3H3 HQGWTXXZVBZBPH-UHFFFAOYSA-N 50042343 (5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL11615 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12280575 103973949 CHEMBL11615 ZINC13759796 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765638 CCCN(CCC)C1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3 MDBWEQVKJDMEMK-UHFFFAOYSA-N 50020221 (-)-5-hydroxy-2-(dipropylamino)tetralin::(-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::5-hydroxy-2-(dipropylamino)tetralin::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (DP-5-ADTN)::CHEMBL273273 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 172267 103931135 CHEMBL273273 128 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769383 CCCCN1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C16H22N2/c1-2-3-9-18-10-5-8-16(13-18)15-7-4-6-14(11-15)12-17/h4,6-7,11,16H,2-3,5,8-10,13H2,1H3/t16-/m1/s1 RBAZQAAINJJBRX-MRXNPFEDSA-N 50039773 3-((S)-1-Butyl-piperidin-3-yl)-benzonitrile::CHEMBL96191 D(2) dopamine receptor Rattus norvegicus 617 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039773&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10354398 103946968 CHEMBL96191 ZINC03785166 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769392 CCCN1CCC[C@H](C1)c1cccc(CCC)c1 InChI=1S/C17H27N/c1-3-7-15-8-5-9-16(13-15)17-10-6-12-18(14-17)11-4-2/h5,8-9,13,17H,3-4,6-7,10-12,14H2,1-2H3/t17-/m1/s1 SXCBTZZPBYWDRW-QGZVFWFLSA-N 50039775 (S)-1-Propyl-3-(3-propyl-phenyl)-piperidine::CHEMBL328785 D(2) dopamine receptor Rattus norvegicus 392 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10060449 103946970 CHEMBL328785 ZINC13738273 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769396 CCCN1CCC[C@H](C1)c1cccc(c1)-c1ccsc1 InChI=1S/C18H23NS/c1-2-9-19-10-4-7-17(13-19)15-5-3-6-16(12-15)18-8-11-20-14-18/h3,5-6,8,11-12,14,17H,2,4,7,9-10,13H2,1H3/t17-/m1/s1 WKZQYOGJYMCSPM-QGZVFWFLSA-N 50039765 (S)-1-Propyl-3-(3-thiophen-3-yl-phenyl)-piperidine::CHEMBL314536 D(2) dopamine receptor Rattus norvegicus 760 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039765 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039765&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11778702 103946960 CHEMBL314536 ZINC13738271 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769417 CCCN1CCC[C@H](C1)c1ccc(OS(=O)(=O)C(F)(F)F)c(OS(=O)(=O)C(F)(F)F)c1 InChI=1S/C16H19F6NO6S2/c1-2-7-23-8-3-4-12(10-23)11-5-6-13(28-30(24,25)15(17,18)19)14(9-11)29-31(26,27)16(20,21)22/h5-6,9,12H,2-4,7-8,10H2,1H3/t12-/m1/s1 DDEDFIYGQWYHBZ-GFCCVEGCSA-N 50039770 CHEMBL328431::Trifluoro-methanesulfonic acid 5-((S)-1-propyl-piperidin-3-yl)-2-trifluoromethanesulfonyloxy-phenyl ester D(2) dopamine receptor Rattus norvegicus 6250 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039770 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039770&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10391240 103946965 CHEMBL328431 ZINC36216535 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769422 CCCN1CCC[C@H](C1)c1cccc(c1)C(=O)OC InChI=1S/C16H23NO2/c1-3-9-17-10-5-8-15(12-17)13-6-4-7-14(11-13)16(18)19-2/h4,6-7,11,15H,3,5,8-10,12H2,1-2H3/t15-/m1/s1 ZWNHEPFDYRKYSD-OAHLLOKOSA-N 50039753 3-((S)-1-Propyl-piperidin-3-yl)-benzoic acid methyl ester::CHEMBL93900 D(2) dopamine receptor Rattus norvegicus 2170 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039753&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10355305 103946948 CHEMBL93900 ZINC13738261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769424 CCCN1CCC[C@H](C1)c1cccc(N)c1 InChI=1S/C14H22N2/c1-2-8-16-9-4-6-13(11-16)12-5-3-7-14(15)10-12/h3,5,7,10,13H,2,4,6,8-9,11,15H2,1H3/t13-/m1/s1 JQISQMHONBYOCE-CYBMUJFWSA-N 50039780 3-((S)-1-Propyl-piperidin-3-yl)-phenylamine::CHEMBL93679 D(2) dopamine receptor Rattus norvegicus 2000 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039780&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10013665 103946975 CHEMBL93679 ZINC13738264 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769452 CCCN1CCC[C@H](C1)c1cccc(Br)c1 InChI=1S/C14H20BrN/c1-2-8-16-9-4-6-13(11-16)12-5-3-7-14(15)10-12/h3,5,7,10,13H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 YHPPFQXIQZIMOW-CYBMUJFWSA-N 50039768 (S)-3-(3-Bromo-phenyl)-1-propyl-piperidine::CHEMBL92817 D(2) dopamine receptor Rattus norvegicus 533 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039768 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039768&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10356389 103946963 CHEMBL92817 ZINC13738266 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769461 CCCN1CCCC2C1CCc1c(OS(=O)(=O)C(F)(F)F)cccc21 InChI=1S/C17H22F3NO3S/c1-2-10-21-11-4-6-13-12-5-3-7-16(14(12)8-9-15(13)21)24-25(22,23)17(18,19)20/h3,5,7,13,15H,2,4,6,8-11H2,1H3 NSTMABOREYEUNT-UHFFFAOYSA-N 50039746 CHEMBL327263::Trifluoro-methanesulfonic acid 4-propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-7-yl ester D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039746&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44325658 103946941 CHEMBL327263 ZINC36187794 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771293 C(N1CCN(CC1)c1nc2ccccc2o1)c1ccccc1 InChI=1S/C18H19N3O/c1-2-6-15(7-3-1)14-20-10-12-21(13-11-20)18-19-16-8-4-5-9-17(16)22-18/h1-9H,10-14H2 YAORDQFXLRHICI-UHFFFAOYSA-N 50041379 2-(4-Benzyl-piperazin-1-yl)-benzooxazole::CHEMBL27896 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041379 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041379&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9971634 103973180 CHEMBL27896 ZINC13736429 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771296 Clc1cccc(c1)N1CCN(CC1)c1nc2ccccc2s1 InChI=1S/C17H16ClN3S/c18-13-4-3-5-14(12-13)20-8-10-21(11-9-20)17-19-15-6-1-2-7-16(15)22-17/h1-7,12H,8-11H2 VCQUFCMLNACVLG-UHFFFAOYSA-N 50041380 2-[4-(3-Chloro-phenyl)-piperazin-1-yl]-benzothiazole::CHEMBL24895 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11724149 103973181 CHEMBL24895 ZINC13736420 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771299 CCOc1ccccc1N1CCN(CC1)c1nc2ccccc2s1 InChI=1S/C19H21N3OS/c1-2-23-17-9-5-4-8-16(17)21-11-13-22(14-12-21)19-20-15-7-3-6-10-18(15)24-19/h3-10H,2,11-14H2,1H3 CVQCHUZYRQWPMY-UHFFFAOYSA-N 50041382 2-[4-(2-Ethoxy-phenyl)-piperazin-1-yl]-benzothiazole::CHEMBL27395 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9974462 103973183 CHEMBL27395 ZINC13736417 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771303 Oc1ccccc1N1CCN(CC1)c1nc2ccccc2s1 InChI=1S/C17H17N3OS/c21-15-7-3-2-6-14(15)19-9-11-20(12-10-19)17-18-13-5-1-4-8-16(13)22-17/h1-8,21H,9-12H2 JYHRLECLGKOLSO-UHFFFAOYSA-N 50041385 2-(4-Benzothiazol-2-yl-piperazin-1-yl)-phenol::CHEMBL27054 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041385&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10244960 103973186 CHEMBL27054 ZINC13736411 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771305 C(N1CCN(CC1)c1nc2ccccc2s1)c1ccc2OCOc2c1 InChI=1S/C19H19N3O2S/c1-2-4-18-15(3-1)20-19(25-18)22-9-7-21(8-10-22)12-14-5-6-16-17(11-14)24-13-23-16/h1-6,11H,7-10,12-13H2 BYHKGNWKJMGHGE-UHFFFAOYSA-N 50041377 2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzothiazole::CHEMBL24909 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127902 103973178 CHEMBL24909 ZINC22309498 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771306 Oc1ccccc1N1CCN(CC1)c1nc2ccccc2o1 InChI=1S/C17H17N3O2/c21-15-7-3-2-6-14(15)19-9-11-20(12-10-19)17-18-13-5-1-4-8-16(13)22-17/h1-8,21H,9-12H2 KBYXPWRYTLGIIC-UHFFFAOYSA-N 50041383 2-(4-Benzooxazol-2-yl-piperazin-1-yl)-phenol::CHEMBL281123 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10334677 103973184 CHEMBL281123 ZINC13736423 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771308 COc1ccccc1N1CCN(CC1)c1nc2ccccc2o1 InChI=1S/C18H19N3O2/c1-22-17-9-5-3-7-15(17)20-10-12-21(13-11-20)18-19-14-6-2-4-8-16(14)23-18/h2-9H,10-13H2,1H3 SDQSWBVZTABORA-UHFFFAOYSA-N 50041378 2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-benzooxazole::CHEMBL25396 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041378 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041378&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10470580 103973179 CHEMBL25396 ZINC13736426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771311 COc1ccccc1N1CCN(CC1)c1nc2ccccc2s1 InChI=1S/C18H19N3OS/c1-22-16-8-4-3-7-15(16)20-10-12-21(13-11-20)18-19-14-6-2-5-9-17(14)23-18/h2-9H,10-13H2,1H3 FSPUGBPPYQTYLN-UHFFFAOYSA-N 50041387 2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-benzothiazole::CHEMBL24854 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041387&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10471573 103973188 CHEMBL24854 ZINC13736414 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771320 C(N1CCN(CC1)c1nc2ccccc2s1)c1ccccc1 InChI=1S/C18H19N3S/c1-2-6-15(7-3-1)14-20-10-12-21(13-11-20)18-19-16-8-4-5-9-17(16)22-18/h1-9H,10-14H2 SNRZSONRAFJJSB-UHFFFAOYSA-N 50041381 2-(4-Benzyl-piperazin-1-yl)-benzothiazole::CHEMBL282234 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041381&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1484933 103973182 CHEMBL282234 ZINC20405012 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771322 COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29) DCSUBABJRXZOMT-UHFFFAOYSA-N 50005836 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide::4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::CHEMBL560739::CISAPRIDE::PROPULSID::US10167299, Cisapride::US10800776, Example Cisapride::US9221790, Cisapride::cid_5311047 D(2) dopamine receptor Rattus norvegicus 680 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005836&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2769 103919261 CHEMBL560739 240 C06910 ZINC03830564 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771325 C(N1CCN(CC1)c1nc2ccccc2o1)c1ccc2OCOc2c1 InChI=1S/C19H19N3O3/c1-2-4-16-15(3-1)20-19(25-16)22-9-7-21(8-10-22)12-14-5-6-17-18(11-14)24-13-23-17/h1-6,11H,7-10,12-13H2 KSTPQTROCLTJMM-UHFFFAOYSA-N 50041388 2-(4-Benzo[1,3]dioxol-5-ylmethyl-piperazin-1-yl)-benzooxazole::CHEMBL26700 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041388&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10065650 103973189 CHEMBL26700 ZINC13736432 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771326 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2.5 ChEMBL 10.1021/jm00035a012 10.7270/Q2PR7WNB 8176710 Monge, A; Pena, MC; Palop, JA; Caldero, JM; Roca, J; Garcia, E; Romero, G; del Rio, J; Lasheras, B CIFA Universidad de Navarra http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774967 CC(=O)c1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)cc1 InChI=1S/C23H25FN2O3/c1-16(27)17-3-6-20(7-4-17)28-14-2-11-26-12-9-18(10-13-26)23-21-8-5-19(24)15-22(21)29-25-23/h3-8,15,18H,2,9-14H2,1H3 TWCSPZZMLVXHAF-UHFFFAOYSA-N 50034032 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-phenyl)-ethanone::CHEMBL14322 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10453356 103942248 CHEMBL14322 ZINC13740849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774969 CC(=O)c1ccc2OC(CCN3CCC(CC3)c3noc4cc(F)ccc34)COc2c1 InChI=1S/C24H25FN2O4/c1-15(28)17-2-5-21-23(12-17)29-14-19(30-21)8-11-27-9-6-16(7-10-27)24-20-4-3-18(25)13-22(20)31-26-24/h2-5,12-13,16,19H,6-11,14H2,1H3 RDYSIFFUFHBZMZ-UHFFFAOYSA-N 50034035 1-(2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2,3-dihydro-benzo[1,4]dioxin-6-yl)-ethanone::CHEMBL14043 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10047977 103942251 CHEMBL14043 ZINC36238014 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774970 COc1cc(ccc1OCCCCN1CCC(CC1)c1noc2ccccc12)C(C)=O InChI=1S/C25H30N2O4/c1-18(28)20-9-10-23(24(17-20)29-2)30-16-6-5-13-27-14-11-19(12-15-27)25-21-7-3-4-8-22(21)31-26-25/h3-4,7-10,17,19H,5-6,11-16H2,1-2H3 ZDCLHBFINMVMFC-UHFFFAOYSA-N 50034034 1-{4-[4-(4-Benzo[d]isoxazol-3-yl-piperidin-1-yl)-butoxy]-3-methoxy-phenyl}-ethanone::CHEMBL274223 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10342195 103942250 CHEMBL274223 ZINC12356411 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774971 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=C InChI=1S/C25H29FN2O3/c1-17(2)19-5-8-22(24(15-19)29-3)30-14-4-11-28-12-9-18(10-13-28)25-21-7-6-20(26)16-23(21)31-27-25/h5-8,15-16,18H,1,4,9-14H2,2-3H3 LOJPKNKPAIBESJ-UHFFFAOYSA-N 50034037 6-Fluoro-3-{1-[3-(4-isopropenyl-2-methoxy-phenoxy)-propyl]-piperidin-4-yl}-benzo[d]isoxazole::CHEMBL14681 D(2) dopamine receptor Rattus norvegicus 221 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034037&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10002473 103942253 CHEMBL14681 ZINC13740865 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774973 CC(=O)c1cc(C)ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C24H27FN2O3/c1-16-4-7-22(21(14-16)17(2)28)29-13-3-10-27-11-8-18(9-12-27)24-20-6-5-19(25)15-23(20)30-26-24/h4-7,14-15,18H,3,8-13H2,1-2H3 WVTCHDNRUWZFHP-UHFFFAOYSA-N 50034038 1-(2-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-5-methyl-phenyl)-ethanone::CHEMBL14494 D(2) dopamine receptor Rattus norvegicus 336 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034038&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10476681 103942254 CHEMBL14494 ZINC13740874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774974 COc1cc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)ccc1C(C)=O InChI=1S/C24H27FN2O4/c1-16(28)20-7-5-19(15-22(20)29-2)30-13-3-10-27-11-8-17(9-12-27)24-21-6-4-18(25)14-23(21)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 XPIKLKLJSVJPIO-UHFFFAOYSA-N 50034039 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-2-methoxy-phenyl)-ethanone::CHEMBL14365 D(2) dopamine receptor Rattus norvegicus 237 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10432600 103942255 CHEMBL14365 ZINC13740872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774976 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(N)=O InChI=1S/C23H26FN3O4/c1-29-21-13-16(23(25)28)3-6-19(21)30-12-2-9-27-10-7-15(8-11-27)22-18-5-4-17(24)14-20(18)31-26-22/h3-6,13-15H,2,7-12H2,1H3,(H2,25,28) JVYDZVFRGFPGPM-UHFFFAOYSA-N 50034040 4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-benzamide::CHEMBL273307 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034040&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10455211 103942256 CHEMBL273307 ZINC13740863 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774979 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)C(F)(F)F InChI=1S/C24H24F4N2O4/c1-32-21-13-16(23(31)24(26,27)28)3-6-19(21)33-12-2-9-30-10-7-15(8-11-30)22-18-5-4-17(25)14-20(18)34-29-22/h3-6,13-15H,2,7-12H2,1H3 BNRQVDABANQSQW-UHFFFAOYSA-N 50034042 2,2,2-Trifluoro-1-(4-{3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14389 D(2) dopamine receptor Rattus norvegicus 169 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034042&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10435274 103942258 CHEMBL14389 ZINC13740862 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774980 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H27FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 XMXHEBAFVSFQEX-UHFFFAOYSA-N 50034043 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14376::ILOPERIDONE D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034043&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71360 103942259 65173 CHEMBL14376 DB04946 87 ZINC01548097 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774983 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(Cl)ccc12)C(C)=O InChI=1S/C24H27ClN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 MXVZSIZAGFKBIP-UHFFFAOYSA-N 50034045 1-(4-{3-[4-(6-Chloro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL273907 D(2) dopamine receptor Rattus norvegicus 111 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10026390 103942261 CHEMBL273907 ZINC13740843 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774984 Nc1ccccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C21H24FN3O2/c22-16-6-7-17-20(14-16)27-24-21(17)15-8-11-25(12-9-15)10-3-13-26-19-5-2-1-4-18(19)23/h1-2,4-7,14-15H,3,8-13,23H2 ADTNCVXMQJPBHL-UHFFFAOYSA-N 50034047 2-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-phenylamine::CHEMBL14538 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10317012 103942263 CHEMBL14538 ZINC13740878 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774985 COc1cc(ccc1OCCN1CCC(CC1)c1noc2cc(Cl)ccc12)C(C)=O InChI=1S/C23H25ClN2O4/c1-15(27)17-3-6-20(22(13-17)28-2)29-12-11-26-9-7-16(8-10-26)23-19-5-4-18(24)14-21(19)30-25-23/h3-6,13-14,16H,7-12H2,1-2H3 AITQIGCIBUOIAD-UHFFFAOYSA-N 50034048 1-(4-{2-[4-(6-Chloro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14361 D(2) dopamine receptor Rattus norvegicus 940 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10342570 103942264 CHEMBL14361 ZINC13740842 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774986 COc1cc(ccc1OCCCCN1CCC(CC1)c1noc2cc(Cl)ccc12)C(C)=O InChI=1S/C25H29ClN2O4/c1-17(29)19-5-8-22(24(15-19)30-2)31-14-4-3-11-28-12-9-18(10-13-28)25-21-7-6-20(26)16-23(21)32-27-25/h5-8,15-16,18H,3-4,9-14H2,1-2H3 YZFVRDOVVWXHEO-UHFFFAOYSA-N 50034044 1-(4-{4-[4-(6-Chloro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-butoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14206 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10344071 103942260 CHEMBL14206 ZINC13740844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774990 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)c1ccccc1 InChI=1S/C29H29FN2O4/c1-34-27-18-22(29(33)21-6-3-2-4-7-21)8-11-25(27)35-17-5-14-32-15-12-20(13-16-32)28-24-10-9-23(30)19-26(24)36-31-28/h2-4,6-11,18-20H,5,12-17H2,1H3 YTLSATPLIMMBNL-UHFFFAOYSA-N 50034052 (4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-phenyl-methanone::CHEMBL14218 D(2) dopamine receptor Rattus norvegicus 460 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10051181 103942268 CHEMBL14218 ZINC13740861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774992 CC(=O)c1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)c(O)c1 InChI=1S/C23H25FN2O4/c1-15(27)17-3-6-21(20(28)13-17)29-12-2-9-26-10-7-16(8-11-26)23-19-5-4-18(24)14-22(19)30-25-23/h3-6,13-14,16,28H,2,7-12H2,1H3 JRAOALKNNYGKLE-UHFFFAOYSA-N 50034051 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-hydroxy-phenyl)-ethanone::CHEMBL14380 D(2) dopamine receptor Rattus norvegicus 8.6 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11742411 103942267 CHEMBL14380 ZINC13740848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774996 COc1cc(ccc1SCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H27FN2O3S/c1-16(28)18-4-7-23(22(14-18)29-2)31-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-21(20)30-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 LMFSAUMXPCITAG-UHFFFAOYSA-N 50034053 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propylsulfanyl}-3-methoxy-phenyl)-ethanone::CHEMBL273633 D(2) dopamine receptor Rattus norvegicus 571 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10321140 103942269 CHEMBL273633 ZINC13740880 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774997 COc1cc(ccc1OCCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C25H29FN2O4/c1-17(29)19-5-8-22(24(15-19)30-2)31-14-4-3-11-28-12-9-18(10-13-28)25-21-7-6-20(26)16-23(21)32-27-25/h5-8,15-16,18H,3-4,9-14H2,1-2H3 URPSWDOKMDDWIR-UHFFFAOYSA-N 50034041 1-(4-{4-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-butoxy}-3-methoxy-phenyl)-ethanone::CHEMBL274039 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034041&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10094790 103942257 CHEMBL274039 ZINC13740847 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774998 CC(=O)c1cccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)c1 InChI=1S/C23H25FN2O3/c1-16(27)18-4-2-5-20(14-18)28-13-3-10-26-11-8-17(9-12-26)23-21-7-6-19(24)15-22(21)29-25-23/h2,4-7,14-15,17H,3,8-13H2,1H3 LZBWQSMPSLARFG-UHFFFAOYSA-N 50034060 1-(3-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-phenyl)-ethanone::CHEMBL14158 D(2) dopamine receptor Rattus norvegicus 454 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034060&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10430858 103942276 CHEMBL14158 ZINC13740877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775000 CSc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H27FN2O3S/c1-16(28)18-4-7-21(23(14-18)31-2)29-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)30-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 BCKYZQRLPGBIMO-UHFFFAOYSA-N 50034055 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methylsulfanyl-phenyl)-ethanone::CHEMBL275064 D(2) dopamine receptor Rattus norvegicus 295 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034055&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10321139 103942271 CHEMBL275064 ZINC13740851 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775001 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)O InChI=1S/C24H29FN2O4/c1-16(28)18-4-7-21(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-6-5-19(25)15-22(20)31-26-24/h4-7,14-17,28H,3,8-13H2,1-2H3 SBKZGLWZGZQVHA-UHFFFAOYSA-N 50034056 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanol::CHEMBL14394 D(2) dopamine receptor Rattus norvegicus 727 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034056&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9823904 103942272 CHEMBL14394 ZINC03991232 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775003 CNc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H28FN3O3/c1-16(29)18-4-7-22(21(14-18)26-2)30-13-3-10-28-11-8-17(9-12-28)24-20-6-5-19(25)15-23(20)31-27-24/h4-7,14-15,17,26H,3,8-13H2,1-2H3 QUUYXXXDMOJYBU-UHFFFAOYSA-N 50034058 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methylamino-phenyl)-ethanone::CHEMBL14306 D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034058&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025444 103942274 CHEMBL14306 ZINC13740852 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775009 COc1cc(ccc1OCCN1CCC(CC1)c1noc2ccccc12)C(C)=O InChI=1S/C23H26N2O4/c1-16(26)18-7-8-21(22(15-18)27-2)28-14-13-25-11-9-17(10-12-25)23-19-5-3-4-6-20(19)29-24-23/h3-8,15,17H,9-14H2,1-2H3 WNCLNNYXHNIVAT-UHFFFAOYSA-N 50034057 1-{4-[2-(4-Benzo[d]isoxazol-3-yl-piperidin-1-yl)-ethoxy]-3-methoxy-phenyl}-ethanone::CHEMBL274462 D(2) dopamine receptor Rattus norvegicus 969 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034057&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10363225 103942273 CHEMBL274462 ZINC12356295 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775015 COc1cc2C(=O)CCCc2cc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C26H29FN2O4/c1-31-24-16-21-18(4-2-5-22(21)30)14-25(24)32-13-3-10-29-11-8-17(9-12-29)26-20-7-6-19(27)15-23(20)33-28-26/h6-7,14-17H,2-5,8-13H2,1H3 CQTCGHFYKNNGHV-UHFFFAOYSA-N 50034064 6-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-7-methoxy-3,4-dihydro-2H-naphthalen-1-one::CHEMBL440768 D(2) dopamine receptor Rattus norvegicus 97 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034064&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10026871 103942280 CHEMBL440768 ZINC13740884 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775018 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)N=O InChI=1S/C24H28FN3O4/c1-16(26-29)18-4-7-21(23(14-18)30-2)31-13-3-10-28-11-8-17(9-12-28)24-20-6-5-19(25)15-22(20)32-27-24/h4-7,14-17H,3,8-13H2,1-2H3 ZWEVROOEBHKSQW-UHFFFAOYSA-N 50034067 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone oxime::CHEMBL276799 D(2) dopamine receptor Rattus norvegicus 90 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54569445 103942283 CHEMBL276799 ZINC13740866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775019 COc1cc2cc[nH]c2cc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C24H26FN3O3/c1-29-22-13-17-5-8-26-20(17)15-23(22)30-12-2-9-28-10-6-16(7-11-28)24-19-4-3-18(25)14-21(19)31-27-24/h3-5,8,13-16,26H,2,6-7,9-12H2,1H3 VEVRYAZMLSNPBA-UHFFFAOYSA-N 50034031 6-Fluoro-3-{1-[3-(5-methoxy-1H-indol-6-yloxy)-propyl]-piperidin-4-yl}-benzo[d]isoxazole::CHEMBL14148 D(2) dopamine receptor Rattus norvegicus 118 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10387589 103942247 CHEMBL14148 ZINC12356405 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775020 CN(C)c1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C25H30FN3O3/c1-17(30)19-5-8-23(22(15-19)28(2)3)31-14-4-11-29-12-9-18(10-13-29)25-21-7-6-20(26)16-24(21)32-27-25/h5-8,15-16,18H,4,9-14H2,1-3H3 ZDTVNXBUVXEOBR-UHFFFAOYSA-N 50034049 1-(3-Dimethylamino-4-{3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-phenyl)-ethanone::CHEMBL14077 D(2) dopamine receptor Rattus norvegicus 116 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10478360 103942265 CHEMBL14077 ZINC13740853 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775022 CC(O)c1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)c(O)c1 InChI=1S/C23H27FN2O4/c1-15(27)17-3-6-21(20(28)13-17)29-12-2-9-26-10-7-16(8-11-26)23-19-5-4-18(24)14-22(19)30-25-23/h3-6,13-16,27-28H,2,7-12H2,1H3 SABFAXRMOAQYKG-UHFFFAOYSA-N 50034065 2-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-5-(1-hydroxy-ethyl)-phenol::CHEMBL14219 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10454460 103942281 CHEMBL14219 ZINC13740858 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775025 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2ccccc12)C(C)=O InChI=1S/C24H28N2O4/c1-17(27)19-8-9-22(23(16-19)28-2)29-15-5-12-26-13-10-18(11-14-26)24-20-6-3-4-7-21(20)30-25-24/h3-4,6-9,16,18H,5,10-15H2,1-2H3 XLLSZDJAXFXJTA-UHFFFAOYSA-N 50034068 1-{4-[3-(4-Benzo[d]isoxazol-3-yl-piperidin-1-yl)-propoxy]-3-methoxy-phenyl}-ethanone::CHEMBL279996 D(2) dopamine receptor Rattus norvegicus 168 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034068&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10024423 103942284 CHEMBL279996 ZINC13740841 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775026 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)N=N InChI=1S/C24H29FN4O3/c1-16(27-26)18-4-7-21(23(14-18)30-2)31-13-3-10-29-11-8-17(9-12-29)24-20-6-5-19(25)15-22(20)32-28-24/h4-7,14-17,26H,3,8-13H2,1-2H3 QCHCYGLWMQANFY-UHFFFAOYSA-N 50034050 CHEMBL275016::[1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-eth-(Z)-ylidene]-hydrazine D(2) dopamine receptor Rattus norvegicus 107 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54220560 103942266 CHEMBL275016 ZINC36238017 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765644 CCCN(CCC)C1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1 InChI=1S/C17H24F3NO3S/c1-3-9-21(10-4-2)15-7-5-13-6-8-16(12-14(13)11-15)24-25(22,23)17(18,19)20/h6,8,12,15H,3-5,7,9-11H2,1-2H3 JVSIKYVCSMXDOZ-UHFFFAOYSA-N 50042340 CHEMBL114433::Trifluoro-methanesulfonic acid 7-dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-yl ester D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14977565 103973946 CHEMBL114433 ZINC36187802 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765646 CCCN(CCC)C1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1 InChI=1S/C17H24F3NO3S/c1-3-10-21(11-4-2)14-9-8-13-6-5-7-16(15(13)12-14)24-25(22,23)17(18,19)20/h5-7,14H,3-4,8-12H2,1-2H3 YEEMKPJFAQAHOW-UHFFFAOYSA-N 50034366 CHEMBL28437::Trifluoro-methanesulfonic acid 7-dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl ester D(2) dopamine receptor Rattus norvegicus 670 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034366&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14973078 103942567 CHEMBL28437 ZINC36187760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765647 CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1 BLYMJBIZMIGWFK-OAHLLOKOSA-N 50054067 (2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium(R(+)7OH-DPAT)::(R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol.HCl::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL301559 D(2) dopamine receptor Rattus norvegicus 340 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603867 103950725 CHEMBL301559 ZINC03870310 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765649 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00074a023 10.7270/Q2S75GZD 7901417 Norman, MH; Kelley, JL; Hollingsworth, EB Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765650 CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-9-5-6-11(19)10-18-16(20)14-13(21-2)8-7-12(17)15(14)22-3/h7-8,11H,4-6,9-10H2,1-3H3,(H,18,20)/t11-/m0/s1 GUJRSXAPGDDABA-NSHDSACASA-N 50026045 (R,S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::(S)-3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide (Remoxipride)::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide(remoxipride)::CHEMBL22242::REMOXIPRIDE D(2) dopamine receptor Rattus norvegicus 1570 ChEMBL 10.1021/jm00074a023 10.7270/Q2S75GZD 7901417 Norman, MH; Kelley, JL; Hollingsworth, EB Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54477 103935779 CHEMBL22242 DB00409 ZINC02021799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765651 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm00074a023 10.7270/Q2S75GZD 7901417 Norman, MH; Kelley, JL; Hollingsworth, EB Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765652 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.920000 ChEMBL 10.1021/jm00074a023 10.7270/Q2S75GZD 7901417 Norman, MH; Kelley, JL; Hollingsworth, EB Burroughs Wellcome Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769473 CCCN1CCC[C@H](C1)c1cccc(SC)c1 InChI=1S/C15H23NS/c1-3-9-16-10-5-7-14(12-16)13-6-4-8-15(11-13)17-2/h4,6,8,11,14H,3,5,7,9-10,12H2,1-2H3/t14-/m1/s1 DQQBAKJEWKQXPD-CQSZACIVSA-N 50039737 (S)-3-(3-Methylsulfanyl-phenyl)-1-propyl-piperidine::CHEMBL92938 D(2) dopamine receptor Rattus norvegicus 849 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039737&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264090 103946932 CHEMBL92938 ZINC06380241 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769475 CC(C)N1CCC[C@H](C1)c1cccc(c1)C#N InChI=1S/C15H20N2/c1-12(2)17-8-4-7-15(11-17)14-6-3-5-13(9-14)10-16/h3,5-6,9,12,15H,4,7-8,11H2,1-2H3/t15-/m1/s1 MCWNRJVMXBUUPG-OAHLLOKOSA-N 50039759 3-((S)-1-Isopropyl-piperidin-3-yl)-benzonitrile::CHEMBL93383 D(2) dopamine receptor Rattus norvegicus 717 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039759&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105186 103946954 CHEMBL93383 ZINC03785165 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50769477 CCCN1CCC[C@H](C1)c1cccc(OC)c1 InChI=1S/C15H23NO/c1-3-9-16-10-5-7-14(12-16)13-6-4-8-15(11-13)17-2/h4,6,8,11,14H,3,5,7,9-10,12H2,1-2H3/t14-/m1/s1 IOENUXNLWXMOQG-CQSZACIVSA-N 50039740 (S)-3-(3-Methoxy-phenyl)-1-propyl-piperidine::CHEMBL93582 D(2) dopamine receptor Rattus norvegicus 3440 ChEMBL 10.1021/jm00043a013 10.7270/Q2J96719 8064801 Sonesson, C; Lin, CH; Hansson, L; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Wikstrom, H University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039740&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12937927 103946935 CHEMBL93582 ZINC13738257 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775027 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 830 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775030 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)N(C)C InChI=1S/C25H30FN3O4/c1-28(2)25(30)18-5-8-21(23(15-18)31-3)32-14-4-11-29-12-9-17(10-13-29)24-20-7-6-19(26)16-22(20)33-27-24/h5-8,15-17H,4,9-14H2,1-3H3 LCIPVHBFQNHEJP-UHFFFAOYSA-N 50034070 4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-N,N-dimethyl-benzamide::CHEMBL14415 D(2) dopamine receptor Rattus norvegicus 127 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034070&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10049666 103942286 CHEMBL14415 ZINC13740864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775032 COc1cc(ccc1NCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C24H28FN3O3/c1-16(29)18-4-7-21(23(14-18)30-2)26-10-3-11-28-12-8-17(9-13-28)24-20-6-5-19(25)15-22(20)31-27-24/h4-7,14-15,17,26H,3,8-13H2,1-2H3 MDVOAKSPEFVXPL-UHFFFAOYSA-N 50034071 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propylamino}-3-methoxy-phenyl)-ethanone::CHEMBL14727 D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034071&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10387699 103942287 CHEMBL14727 ZINC13740881 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775033 COc1cc(ccc1OCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C23H25FN2O4/c1-15(27)17-3-6-20(22(13-17)28-2)29-12-11-26-9-7-16(8-10-26)23-19-5-4-18(24)14-21(19)30-25-23/h3-6,13-14,16H,7-12H2,1-2H3 GUFAQOUWNNKLJJ-UHFFFAOYSA-N 50034069 1-(4-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethoxy}-3-methoxy-phenyl)-ethanone::CHEMBL276750 D(2) dopamine receptor Rattus norvegicus 427 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034069&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10431812 103942285 CHEMBL276750 ZINC13740846 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775039 COc1cc(cc(OC)c1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C25H29FN2O5/c1-16(29)18-13-22(30-2)25(23(14-18)31-3)32-12-4-9-28-10-7-17(8-11-28)24-20-6-5-19(26)15-21(20)33-27-24/h5-6,13-15,17H,4,7-12H2,1-3H3 GWTRXOMITGLYGF-UHFFFAOYSA-N 50034072 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3,5-dimethoxy-phenyl)-ethanone::CHEMBL14395 D(2) dopamine receptor Rattus norvegicus 45 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034072&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9981483 103942288 CHEMBL14395 ZINC13740856 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775040 COc1ccccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C22H25FN2O3/c1-26-19-5-2-3-6-20(19)27-14-4-11-25-12-9-16(10-13-25)22-18-8-7-17(23)15-21(18)28-24-22/h2-3,5-8,15-16H,4,9-14H2,1H3 HDATZBFHKKNXAD-UHFFFAOYSA-N 50034075 6-Fluoro-3-{1-[3-(2-methoxy-phenoxy)-propyl]-piperidin-4-yl}-benzo[d]isoxazole::CHEMBL14539 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034075&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10452601 103942291 CHEMBL14539 ZINC13740871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775043 COc1ccc(N)cc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C22H26FN3O3/c1-27-19-6-4-17(24)14-21(19)28-12-2-9-26-10-7-15(8-11-26)22-18-5-3-16(23)13-20(18)29-25-22/h3-6,13-15H,2,7-12,24H2,1H3 GYKOWUGFJRYKTC-UHFFFAOYSA-N 50034077 3-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-4-methoxy-phenylamine::CHEMBL14610 D(2) dopamine receptor Rattus norvegicus 112 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034077&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10046480 103942293 CHEMBL14610 ZINC13740876 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775048 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccccc2)CC1 InChI=1S/C21H23FN2O2/c22-17-7-8-19-20(15-17)26-23-21(19)16-9-12-24(13-10-16)11-4-14-25-18-5-2-1-3-6-18/h1-3,5-8,15-16H,4,9-14H2 PQMOOBYYHQPYLZ-UHFFFAOYSA-N 50034046 6-Fluoro-3-[1-(3-phenoxy-propyl)-piperidin-4-yl]-benzo[d]isoxazole::CHEMBL427822 D(2) dopamine receptor Rattus norvegicus 364 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034046&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473320 103942262 CHEMBL427822 ZINC12356171 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775049 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C#N InChI=1S/C23H24FN3O3/c1-28-22-13-16(15-25)3-6-20(22)29-12-2-9-27-10-7-17(8-11-27)23-19-5-4-18(24)14-21(19)30-26-23/h3-6,13-14,17H,2,7-12H2,1H3 DTBWJCOEWPYXNX-UHFFFAOYSA-N 50034074 4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-benzonitrile::CHEMBL14509 D(2) dopamine receptor Rattus norvegicus 111 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034074&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10047113 103942290 CHEMBL14509 ZINC13740869 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775050 CCOc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C25H29FN2O4/c1-3-30-24-15-19(17(2)29)5-8-22(24)31-14-4-11-28-12-9-18(10-13-28)25-21-7-6-20(26)16-23(21)32-27-25/h5-8,15-16,18H,3-4,9-14H2,1-2H3 ASPBVUBBCSOPSY-UHFFFAOYSA-N 50034073 1-(3-Ethoxy-4-{3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-phenyl)-ethanone::CHEMBL436141 D(2) dopamine receptor Rattus norvegicus 127 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034073&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10026262 103942289 CHEMBL436141 ZINC13740855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775052 COc1ccc(NC(C)=O)cc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C24H28FN3O4/c1-16(29)26-19-5-7-21(30-2)23(15-19)31-13-3-10-28-11-8-17(9-12-28)24-20-6-4-18(25)14-22(20)32-27-24/h4-7,14-15,17H,3,8-13H2,1-2H3,(H,26,29) KJAGCMXHUYDGQP-UHFFFAOYSA-N 50034063 CHEMBL14470::N-(3-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-4-methoxy-phenyl)-acetamide D(2) dopamine receptor Rattus norvegicus 147 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034063&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10343244 103942279 CHEMBL14470 ZINC13740875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775053 CC(=O)c1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)c(C)c1 InChI=1S/C24H27FN2O3/c1-16-14-19(17(2)28)4-7-22(16)29-13-3-10-27-11-8-18(9-12-27)24-21-6-5-20(25)15-23(21)30-26-24/h4-7,14-15,18H,3,8-13H2,1-2H3 VHLOULCGYCOACM-UHFFFAOYSA-N 50034062 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methyl-phenyl)-ethanone::CHEMBL14556 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034062&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10319381 103942278 CHEMBL14556 ZINC13740850 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775055 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775056 CC(=O)Nc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(C)=O InChI=1S/C25H28FN3O4/c1-16(30)19-4-7-23(22(14-19)27-17(2)31)32-13-3-10-29-11-8-18(9-12-29)25-21-6-5-20(26)15-24(21)33-28-25/h4-7,14-15,18H,3,8-13H2,1-2H3,(H,27,31) NXTZIWVLIMODNI-UHFFFAOYSA-N 50034076 CHEMBL14393::N-(5-Acetyl-2-{3-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-phenyl)-acetamide D(2) dopamine receptor Rattus norvegicus 107 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034076&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10321674 103942292 CHEMBL14393 ZINC13740854 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775057 COc1cc(ccc1OCCCN1CCC(CC1)c1noc2ccc(F)cc12)C(C)=O InChI=1S/C24H27FN2O4/c1-16(28)18-4-6-22(23(14-18)29-2)30-13-3-10-27-11-8-17(9-12-27)24-20-15-19(25)5-7-21(20)31-26-24/h4-7,14-15,17H,3,8-13H2,1-2H3 BNEJDVPNHDRBGW-UHFFFAOYSA-N 50034054 1-(4-{3-[4-(5-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-ethanone::CHEMBL14522 D(2) dopamine receptor Rattus norvegicus 455 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034054&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10320252 103942270 CHEMBL14522 ZINC13740845 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775060 COc1cc(Br)ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C22H24BrFN2O3/c1-27-21-13-16(23)3-6-19(21)28-12-2-9-26-10-7-15(8-11-26)22-18-5-4-17(24)14-20(18)29-25-22/h3-6,13-15H,2,7-12H2,1H3 YHSBVXZDWKZHDZ-UHFFFAOYSA-N 50034066 3-{1-[3-(4-Bromo-2-methoxy-phenoxy)-propyl]-piperidin-4-yl}-6-fluoro-benzo[d]isoxazole::CHEMBL14246 D(2) dopamine receptor Rattus norvegicus 262 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034066&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10004580 103942282 CHEMBL14246 ZINC13740870 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775062 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775064 CC(=O)c1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)cc1C InChI=1S/C24H27FN2O3/c1-16-14-20(5-7-21(16)17(2)28)29-13-3-10-27-11-8-18(9-12-27)24-22-6-4-19(25)15-23(22)30-26-24/h4-7,14-15,18H,3,8-13H2,1-2H3 WKMBYFWOGYETAT-UHFFFAOYSA-N 50034059 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-2-methyl-phenyl)-ethanone::CHEMBL417620 D(2) dopamine receptor Rattus norvegicus 182 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034059&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10386866 103942275 CHEMBL417620 ZINC13740873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775066 CCCCC(=O)c1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)c(OC)c1 InChI=1S/C27H33FN2O4/c1-3-4-6-23(31)20-7-10-24(26(17-20)32-2)33-16-5-13-30-14-11-19(12-15-30)27-22-9-8-21(28)18-25(22)34-29-27/h7-10,17-19H,3-6,11-16H2,1-2H3 DVUZZRUXGKHQQK-UHFFFAOYSA-N 50034078 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-pentan-1-one::CHEMBL14348 D(2) dopamine receptor Rattus norvegicus 242 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034078&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10027633 103942294 CHEMBL14348 ZINC13740860 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775067 CCc1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)c(OC)c1 InChI=1S/C24H29FN2O3/c1-3-17-5-8-21(23(15-17)28-2)29-14-4-11-27-12-9-18(10-13-27)24-20-7-6-19(25)16-22(20)30-26-24/h5-8,15-16,18H,3-4,9-14H2,1-2H3 HVPFIEOSMSVBFR-UHFFFAOYSA-N 50034033 3-{1-[3-(4-Ethyl-2-methoxy-phenoxy)-propyl]-piperidin-4-yl}-6-fluoro-benzo[d]isoxazole::CHEMBL14510 D(2) dopamine receptor Rattus norvegicus 213 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9979063 103942249 CHEMBL14510 ZINC13740868 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775070 CCC(=O)c1ccc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)c(OC)c1 InChI=1S/C25H29FN2O4/c1-3-21(29)18-5-8-22(24(15-18)30-2)31-14-4-11-28-12-9-17(10-13-28)25-20-7-6-19(26)16-23(20)32-27-25/h5-8,15-17H,3-4,9-14H2,1-2H3 NDYOGQKCYHHFLA-UHFFFAOYSA-N 50034079 1-(4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-3-methoxy-phenyl)-propan-1-one::CHEMBL14163 D(2) dopamine receptor Rattus norvegicus 135 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034079&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10071945 103942295 CHEMBL14163 ZINC13740859 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50775071 CNc1ccccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C22H26FN3O2/c1-24-19-5-2-3-6-20(19)27-14-4-11-26-12-9-16(10-13-26)22-18-8-7-17(23)15-21(18)28-25-22/h2-3,5-8,15-16,24H,4,9-14H2,1H3 BDNXZVDZNNJIJO-UHFFFAOYSA-N 50034061 (2-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propoxy}-phenyl)-methyl-amine::CHEMBL14100 D(2) dopamine receptor Rattus norvegicus 246 ChEMBL 10.1021/jm00007a009 10.7270/Q2S75H08 7707315 Strupczewski, JT; Bordeau, KJ; Chiang, Y; Glamkowski, EJ; Conway, PG; Corbett, R; Hartman, HB; Szewczak, MR; Wilmot, CA; Helsley, GC Hoechst-Roussel Pharmaceuticals Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034061&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10407614 103942277 CHEMBL14100 ZINC13740879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780592 CCCCCc1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C20H25NO2S/c1-2-3-4-5-13-9-15-19(24-13)11-21-16-7-6-12-8-17(22)18(23)10-14(12)20(15)16/h8-10,16,20-23H,2-7,11H2,1H3/t16-,20+/m0/s1 XNVUFMZAHXMTCP-OXJNMPFZSA-N 50057838 (5aS,11bR)-2-Pentyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL38757 D(2) dopamine receptor Rattus norvegicus 2090 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057838&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10854877 103953817 CHEMBL38757 ZINC13762026 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780597 CCCCc1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C19H23NO2S/c1-2-3-4-12-8-14-18(23-12)10-20-15-6-5-11-7-16(21)17(22)9-13(11)19(14)15/h7-9,15,19-22H,2-6,10H2,1H3/t15-,19+/m0/s1 HOPSYZDZFWQWGW-HNAYVOBHSA-N 50057839 (5aS,11bR)-2-Butyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL417164 D(2) dopamine receptor Rattus norvegicus 1320 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10664137 103953818 CHEMBL417164 ZINC13762024 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780611 Oc1cc2CC[C@@H]3NCc4ccsc4[C@H]3c2cc1O InChI=1S/C15H15NO2S/c17-12-5-8-1-2-11-14(10(8)6-13(12)18)15-9(7-16-11)3-4-19-15/h3-6,11,14,16-18H,1-2,7H2/t11-,14-/m0/s1 YWMQJPWBNVVTRC-FZMZJTMJSA-N 50057837 (5aS,11bS)-4,5,5a,6,7,11b-Hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL288536 D(2) dopamine receptor Rattus norvegicus 340 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057837&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10540201 103953816 CHEMBL288536 ZINC13762002 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780616 Cc1cccc(c1)-c1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C22H21NO2S/c1-12-3-2-4-14(7-12)20-10-16-21(26-20)11-23-17-6-5-13-8-18(24)19(25)9-15(13)22(16)17/h2-4,7-10,17,22-25H,5-6,11H2,1H3/t17-,22+/m0/s1 GKLDXZHGPYSMOV-HTAPYJJXSA-N 50057847 (5aS,11bR)-2-m-Tolyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL416435 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10666423 103953826 CHEMBL416435 ZINC13762038 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780620 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus 2900 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780632 Oc1cc2CC[C@@H]3NCc4sc(Cl)cc4[C@H]3c2cc1O InChI=1S/C15H14ClNO2S/c16-14-5-9-13(20-14)6-17-10-2-1-7-3-11(18)12(19)4-8(7)15(9)10/h3-5,10,15,17-19H,1-2,6H2/t10-,15+/m0/s1 LBAJYRVVNVZIJA-ZUZCIYMTSA-N 50057848 (5aS,11bR)-2-Chloro-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL39266 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057848&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10733562 103953827 CHEMBL39266 ZINC13762040 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780634 CCCCCCc1cc2CN[C@H]3CCc4cc(O)c(O)cc4[C@@H]3c2s1 InChI=1S/C21H27NO2S/c1-2-3-4-5-6-15-9-14-12-22-17-8-7-13-10-18(23)19(24)11-16(13)20(17)21(14)25-15/h9-11,17,20,22-24H,2-8,12H2,1H3/t17-,20-/m0/s1 RPOAEKBVMRYCPD-PXNSSMCTSA-N 50057850 (5aS,11bS)-2-Hexyl-4,5,5a,6,7,11b-hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL289927 D(2) dopamine receptor Rattus norvegicus 540 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057850&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10666053 103953829 CHEMBL289927 ZINC13762010 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780643 Oc1cc2CC[C@@H]3NCc4cc(CC5CCCC5)sc4[C@H]3c2cc1O InChI=1S/C21H25NO2S/c23-18-9-13-5-6-17-20(16(13)10-19(18)24)21-14(11-22-17)8-15(25-21)7-12-3-1-2-4-12/h8-10,12,17,20,22-24H,1-7,11H2/t17-,20-/m0/s1 TZIQBANCPDRLOK-PXNSSMCTSA-N 50057844 (5aS,11bS)-2-Cyclopentylmethyl-4,5,5a,6,7,11b-hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL287931 D(2) dopamine receptor Rattus norvegicus 560 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10689581 103953823 CHEMBL287931 ZINC13762014 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780648 Oc1cc2CC[C@H]3NCc4cscc4[C@@H]3c2cc1O InChI=1S/C15H15NO2S/c17-13-3-8-1-2-12-15(10(8)4-14(13)18)11-7-19-6-9(11)5-16-12/h3-4,6-7,12,15-18H,1-2,5H2/t12-,15+/m1/s1 QBDQCABBBJIVGT-DOMZBBRYSA-N 50057840 (5aR,11bS)-4,5,5a,6,7,11b-Hexahydro-2-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol; hydrobromide::CHEMBL554571 D(2) dopamine receptor Rattus norvegicus 1030 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057840&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10588327 103953819 CHEMBL554571 ZINC13762042 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780649 Oc1cc2CC[C@@H]3NCc4cc(sc4[C@H]3c2cc1O)C1CCCCC1 InChI=1S/C21H25NO2S/c23-17-8-13-6-7-16-20(15(13)10-18(17)24)21-14(11-22-16)9-19(25-21)12-4-2-1-3-5-12/h8-10,12,16,20,22-24H,1-7,11H2/t16-,20-/m0/s1 RSAXYFBXTHUFBC-JXFKEZNVSA-N 50057832 (5aS,11bS)-2-Cyclohexyl-4,5,5a,6,7,11b-hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL41196 D(2) dopamine receptor Rattus norvegicus 1530 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057832&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10546132 103953811 CHEMBL41196 ZINC13762012 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780653 Oc1cc2CC[C@H]3NCc4ccsc4[C@H]3c2cc1O InChI=1S/C15H15NO2S/c17-12-5-8-1-2-11-14(10(8)6-13(12)18)15-9(7-16-11)3-4-19-15/h3-6,11,14,16-18H,1-2,7H2/t11-,14+/m1/s1 YWMQJPWBNVVTRC-RISCZKNCSA-N 50057853 (5aR,11bS)-4,5,5a,6,7,11b-Hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol; hydrobromide::CHEMBL542593 D(2) dopamine receptor Rattus norvegicus 2800 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10802235 103953832 CHEMBL542593 ZINC13762020 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780661 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Rattus norvegicus 1400 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780662 CC(C)Cc1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C19H23NO2S/c1-10(2)5-12-7-14-18(23-12)9-20-15-4-3-11-6-16(21)17(22)8-13(11)19(14)15/h6-8,10,15,19-22H,3-5,9H2,1-2H3/t15-,19+/m0/s1 JUSHFFHTINWVIE-HNAYVOBHSA-N 50057855 (5aS,11bR)-2-Isobutyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL288846 D(2) dopamine receptor Rattus norvegicus 2560 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10592479 103953834 CHEMBL288846 ZINC13762030 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780666 Oc1cc2CC[C@@H]3NCc4sc(cc4[C@H]3c2cc1O)-c1ccccc1 InChI=1S/C21H19NO2S/c23-17-8-13-6-7-16-21(14(13)9-18(17)24)15-10-19(25-20(15)11-22-16)12-4-2-1-3-5-12/h1-5,8-10,16,21-24H,6-7,11H2/t16-,21+/m0/s1 KMEFMCVBQGTUCT-HRAATJIYSA-N 50057851 (5aS,11bR)-2-Phenyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL43514 D(2) dopamine receptor Rattus norvegicus 2590 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10497993 103953830 CHEMBL43514 ZINC13762036 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780687 CCCc1csc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc12 InChI=1S/C18H21NO2S/c1-2-3-11-9-22-18-13(11)8-19-14-5-4-10-6-15(20)16(21)7-12(10)17(14)18/h6-7,9,14,17,19-21H,2-5,8H2,1H3/t14-,17-/m1/s1 KORFPJPKHFBFSL-RHSMWYFYSA-N 50057858 (5aR,11bR)-3-Propyl-4,5,5a,6,7,11b-hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol; hydrochloride::CHEMBL542351 D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44287454 103953837 CHEMBL542351 ZINC13762046 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780693 CC(C)(C)c1cc2CN[C@H]3CCc4cc(O)c(O)cc4[C@@H]3c2s1 InChI=1S/C19H23NO2S/c1-19(2,3)16-7-11-9-20-13-5-4-10-6-14(21)15(22)8-12(10)17(13)18(11)23-16/h6-8,13,17,20-22H,4-5,9H2,1-3H3/t13-,17-/m0/s1 FZGYMZTVBMODJR-GUYCJALGSA-N 50057852 (5aS,11bS)-2-tert-Butyl-4,5,5a,6,7,11b-hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL291100 D(2) dopamine receptor Rattus norvegicus 910 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10758744 103953831 CHEMBL291100 ZINC13762018 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780700 CCc1cc2CN[C@H]3CCc4cc(O)c(O)cc4[C@@H]3c2s1 InChI=1S/C17H19NO2S/c1-2-11-5-10-8-18-13-4-3-9-6-14(19)15(20)7-12(9)16(13)17(10)21-11/h5-7,13,16,18-20H,2-4,8H2,1H3/t13-,16-/m0/s1 LBZXCIYZKGQQCJ-BBRMVZONSA-N 50057842 (5aS,11bS)-2-Ethyl-4,5,5a,6,7,11b-hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL44414 D(2) dopamine receptor Rattus norvegicus 145 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057842&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10851849 103953821 CHEMBL44414 ZINC03808893 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780701 Cc1cc2CN[C@H]3CCc4cc(O)c(O)cc4[C@@H]3c2s1 InChI=1S/C16H17NO2S/c1-8-4-10-7-17-12-3-2-9-5-13(18)14(19)6-11(9)15(12)16(10)20-8/h4-6,12,15,17-19H,2-3,7H2,1H3/t12-,15-/m0/s1 GYRLGNMXIAYTEM-WFASDCNBSA-N 50057846 (5aS,11bS)-2-Methyl-4,5,5a,6,7,11b-hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL41132 D(2) dopamine receptor Rattus norvegicus 205 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057846&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10684715 103953825 CHEMBL41132 ZINC13762004 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780704 Oc1cc2CC[C@@H]3NCc4sccc4[C@H]3c2cc1O InChI=1S/C15H15NO2S/c17-12-5-8-1-2-11-15(10(8)6-13(12)18)9-3-4-19-14(9)7-16-11/h3-6,11,15-18H,1-2,7H2/t11-,15-/m0/s1 UUGICWXWTLQAGO-NHYWBVRUSA-N 50057843 (5aS,11bR)-4,5,5a,6,7,11b-Hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL40950 D(2) dopamine receptor Rattus norvegicus 1290 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10588326 103953822 CHEMBL40950 ZINC13762022 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780711 CCCc1scc2[C@H]3[C@@H](CCc4cc(O)c(O)cc34)NCc12 InChI=1S/C18H21NO2S/c1-2-3-17-12-8-19-14-5-4-10-6-15(20)16(21)7-11(10)18(14)13(12)9-22-17/h6-7,9,14,18-21H,2-5,8H2,1H3/t14-,18+/m1/s1 WDHPIPIHLLCKBB-KDOFPFPSSA-N 50057856 (5aR,11bS)-3-Propyl-4,5,5a,6,7,11b-hexahydro-2-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol; TFA::CHEMBL41238 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10519436 103953835 CHEMBL41238 ZINC13762044 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780713 CCCCc1cc2CN[C@H]3CCc4cc(O)c(O)cc4[C@@H]3c2s1 InChI=1S/C19H23NO2S/c1-2-3-4-13-7-12-10-20-15-6-5-11-8-16(21)17(22)9-14(11)18(15)19(12)23-13/h7-9,15,18,20-22H,2-6,10H2,1H3/t15-,18-/m0/s1 SDSOUSANKZZJNT-YJBOKZPZSA-N 50057845 (5aS,11bS)-2-Butyl-4,5,5a,6,7,11b-hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL289867 D(2) dopamine receptor Rattus norvegicus 450 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10830234 103953824 CHEMBL289867 ZINC13762008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780721 Oc1cc2CC[C@@H]3NCc4cc(Cl)sc4[C@H]3c2cc1O InChI=1S/C15H14ClNO2S/c16-13-4-8-6-17-10-2-1-7-3-11(18)12(19)5-9(7)14(10)15(8)20-13/h3-5,10,14,17-19H,1-2,6H2/t10-,14-/m0/s1 IFZPBOWTIKDDCU-HZMBPMFUSA-N 50057833 (5aS,11bS)-2-Chloro-4,5,5a,6,7,11b-hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL290842 D(2) dopamine receptor Rattus norvegicus 145 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057833&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10518837 103953812 CHEMBL290842 ZINC13762016 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771605 OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2 ZXUYYZPJUGQHLQ-UHFFFAOYSA-N 50002238 (R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::(S)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-1-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol(BMY-14802)::1-(4-Fluoro-phenyl)-4-[4-(4-fluoro-phenyl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol(BMY-14802)::1-(4-fluorophenyl)-4-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl)butan-1-ol::4-{4-[5-Fluoro-2-(4-fluoro-phenyl)-2H-pyrimidin-1-yl]-piperazin-1-yl}-butan-1-ol::4-{4-[5-Fluoro-2-(4-fluoro-phenyl)-2H-pyrimidin-1-yl]-piperazin-1-yl}-butan-1-ol(BMY 14802)::BMY-14802::CHEMBL60859 D(2) dopamine receptor Rattus norvegicus 8400 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002238&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 108046 103916544 CHEMBL60859 8 ZINC03995923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771606 Fc1ccc(cc1)C1=CC2CCC(C1)N2CCCCc1cn(-c2ccc(F)cc2)c2ccccc12 InChI=1S/C31H30F2N2/c32-25-10-8-22(9-11-25)24-19-28-16-17-29(20-24)34(28)18-4-3-5-23-21-35(27-14-12-26(33)13-15-27)31-7-2-1-6-30(23)31/h1-2,6-15,19,21,28-29H,3-5,16-18,20H2 NRZHEKZOMMPQDG-UHFFFAOYSA-N 50035098 1-(4-Fluoro-phenyl)-3-{4-[3-(4-fluoro-phenyl)-8-aza-bicyclo[3.2.1]oct-2-en-8-yl]-butyl}-1H-indole::CHEMBL62994 D(2) dopamine receptor Rattus norvegicus 8000 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035098&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15205887 103943146 CHEMBL62994 ZINC01542666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771607 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 7.5 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771608 COc1ccccc1N1CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H29N3O/c1-27-23-12-5-4-11-22(23)26-16-14-25(15-17-26)13-7-6-8-19-18-24-21-10-3-2-9-20(19)21/h2-5,9-12,18,24H,6-8,13-17H2,1H3 LPGUYDKCWIULOY-UHFFFAOYSA-N 50035094 3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL59940 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035094&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10451368 103943142 CHEMBL59940 ZINC13741504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771618 C(CCc1c[nH]c2ccccc12)CN1CCC2(CC1)OCc1ccccc21 InChI=1S/C24H28N2O/c1-3-10-22-20(8-1)18-27-24(22)12-15-26(16-13-24)14-6-5-7-19-17-25-23-11-4-2-9-21(19)23/h1-4,8-11,17,25H,5-7,12-16,18H2 GOIYUNROIAKNAE-UHFFFAOYSA-N 50035101 1'-[4-(1H-3-indolyl)butyl]spiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]::CHEMBL59464 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035101&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473699 103943149 CHEMBL59464 ZINC29570933 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771619 Fc1ccc(cc1)C1CCN(CCCCc2cn(-c3ccc(F)cc3)c3ccccc23)CC1 InChI=1S/C29H30F2N2/c30-25-10-8-22(9-11-25)23-16-19-32(20-17-23)18-4-3-5-24-21-33(27-14-12-26(31)13-15-27)29-7-2-1-6-28(24)29/h1-2,6-15,21,23H,3-5,16-20H2 NGVLXUDHOKGWPG-UHFFFAOYSA-N 50035102 1-(4-Fluoro-phenyl)-3-{4-[4-(4-fluoro-phenyl)-piperidin-1-yl]-butyl}-1H-indole::CHEMBL61539 D(2) dopamine receptor Rattus norvegicus 4200 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035102&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10049124 103943150 CHEMBL61539 ZINC01542665 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771624 C(N1CCC2(CCCc3ccccc23)CC1)c1ccccc1 InChI=1S/C21H25N/c1-2-7-18(8-3-1)17-22-15-13-21(14-16-22)12-6-10-19-9-4-5-11-20(19)21/h1-5,7-9,11H,6,10,12-17H2 MLDCBJPLHBPJET-UHFFFAOYSA-N 50035097 1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-piperidine](L-687,384)::1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-piperidine]; HCl::1''-benzylspiro[1,2,3,4-tetrahydronaphthalene-1,4''-(hexahydropyridine)]::1'-benzylspiro[1,2,3,4-tetrahydronaphthalene-1,4'-(hexahydropyridine)](L-687,384)::CHEMBL1256916::CHEMBL303336::L-687384 D(2) dopamine receptor Rattus norvegicus 3700 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035097&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 125328 103943145 CHEMBL1256916CHEMBL303336 ZINC01493052 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771625 Fc1ccc(cc1)-n1cc(CCCCN2CCC3(CC2)OCc2ccccc32)c2ccccc12 InChI=1S/C30H31FN2O/c31-25-12-14-26(15-13-25)33-21-23(27-9-2-4-11-29(27)33)7-5-6-18-32-19-16-30(17-20-32)28-10-3-1-8-24(28)22-34-30/h1-4,8-15,21H,5-7,16-20,22H2 XWAONOGAGZNUSF-UHFFFAOYSA-N 50035105 1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]::1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)](Lu 28-179)::CHEMBL61479::Lu 28-179::Siramesine D(2) dopamine receptor Rattus norvegicus 800 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035105&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9829526 103943153 CHEMBL61479 ZINC01533883 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777057 COc1cccc2C(CCCc12)NC(=O)CCN1CCN(CC1)c1ccccn1 InChI=1S/C23H30N4O2/c1-29-21-9-5-6-18-19(21)7-4-8-20(18)25-23(28)11-13-26-14-16-27(17-15-26)22-10-2-3-12-24-22/h2-3,5-6,9-10,12,20H,4,7-8,11,13-17H2,1H3,(H,25,28) YPSAZTJQMLGSGT-UHFFFAOYSA-N 50052556 CHEMBL323242::N-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-3-(4-pyridin-2-yl-piperazin-1-yl)-propionamide D(2) dopamine receptor Rattus norvegicus 1900 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052556&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10715654 103949408 CHEMBL323242 ZINC13757369 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777068 COc1cccc2C(CCCc12)NCCCN1CCN(CC1)c1ccccc1 InChI=1S/C24H33N3O/c1-28-24-13-6-10-21-22(24)11-5-12-23(21)25-14-7-15-26-16-18-27(19-17-26)20-8-3-2-4-9-20/h2-4,6,8-10,13,23,25H,5,7,11-12,14-19H2,1H3 JVGJNXVXHQYNTM-UHFFFAOYSA-N 50052567 (5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-[3-(4-phenyl-piperazin-1-yl)-propyl]-amine::CHEMBL325079 D(2) dopamine receptor Rattus norvegicus 2160 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10523786 103949419 CHEMBL325079 ZINC13757348 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777069 COc1ccccc1N1CCN(CCN(C)C(=O)C2CCCc3c(OC)cccc23)CC1 InChI=1S/C26H35N3O3/c1-27(26(30)22-10-6-9-21-20(22)8-7-13-24(21)31-2)14-15-28-16-18-29(19-17-28)23-11-4-5-12-25(23)32-3/h4-5,7-8,11-13,22H,6,9-10,14-19H2,1-3H3 ZHOHSCVJNOKADU-UHFFFAOYSA-N 50052558 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-methyl-amide::CHEMBL321184 D(2) dopamine receptor Rattus norvegicus 332 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052558&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797259 103949410 CHEMBL321184 ZINC13757333 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777073 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777078 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3)CCCc12 InChI=1S/C24H32N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h2-4,6,10-12,14,20H,5,7-9,13,15-19H2,1H3 JGCUFOXBUYJGBX-UHFFFAOYSA-N 50033857 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL322275 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10361439 103942105 CHEMBL322275 ZINC13740694 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777083 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C25H34N2O2/c1-28-24-14-6-10-21-20(8-5-11-22(21)24)9-7-15-26-16-18-27(19-17-26)23-12-3-4-13-25(23)29-2/h3-4,6,10,12-14,20H,5,7-9,11,15-19H2,1-2H3 INGWKGCHJJYQIB-UHFFFAOYSA-N 50033839 1-(2-Methoxy-phenyl)-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL26929 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10385977 103942087 CHEMBL26929 ZINC13740674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777085 COc1cccc2C(CCCc12)C(=O)NCCCN1CCN(CC1)c1ccccc1OC InChI=1S/C26H35N3O3/c1-31-24-13-6-8-20-21(24)9-5-10-22(20)26(30)27-14-7-15-28-16-18-29(19-17-28)23-11-3-4-12-25(23)32-2/h3-4,6,8,11-13,22H,5,7,9-10,14-19H2,1-2H3,(H,27,30) LTLCYGQKNCSZNO-UHFFFAOYSA-N 50052565 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-amide::CHEMBL110968 D(2) dopamine receptor Rattus norvegicus 116 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10812885 103949417 CHEMBL110968 ZINC13757324 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777094 COc1cccc2C(CCCc12)C(=O)NCCN1CCN(CC1)c1ccccn1 InChI=1S/C23H30N4O2/c1-29-21-9-5-6-18-19(21)7-4-8-20(18)23(28)25-12-13-26-14-16-27(17-15-26)22-10-2-3-11-24-22/h2-3,5-6,9-11,20H,4,7-8,12-17H2,1H3,(H,25,28) FLUORPLKDHALHQ-UHFFFAOYSA-N 50052557 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid [2-(4-pyridin-2-yl-piperazin-1-yl)-ethyl]-amide::CHEMBL107503 D(2) dopamine receptor Rattus norvegicus 2440 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052557 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052557&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10620661 103949409 CHEMBL107503 ZINC13757316 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777100 COc1cccc2C(CCCc12)C(=O)NCCCN1CCN(CC1)c1ccccn1 InChI=1S/C24H32N4O2/c1-30-22-10-5-7-19-20(22)8-4-9-21(19)24(29)26-13-6-14-27-15-17-28(18-16-27)23-11-2-3-12-25-23/h2-3,5,7,10-12,21H,4,6,8-9,13-18H2,1H3,(H,26,29) GECKXGAYBCMYGN-UHFFFAOYSA-N 50052560 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid [3-(4-pyridin-2-yl-piperazin-1-yl)-propyl]-amide::CHEMBL324637 D(2) dopamine receptor Rattus norvegicus 819 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052560 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052560&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10763976 103949412 CHEMBL324637 ZINC12356345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777104 COc1cccc2C(CCCN3CCN(CC3)c3ccccn3)CCCc12 InChI=1S/C23H31N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-3,5,9,11-13,19H,4,6-8,10,14-18H2,1H3 KKPMYWNQZNRGIK-UHFFFAOYSA-N 50033852 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL444590 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10474042 103942100 CHEMBL444590 ZINC13470658 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777106 COc1cccc2C(CCCc12)C(=O)NCCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H33N3O3/c1-30-23-12-6-7-19-20(23)8-5-9-21(19)25(29)26-13-14-27-15-17-28(18-16-27)22-10-3-4-11-24(22)31-2/h3-4,6-7,10-12,21H,5,8-9,13-18H2,1-2H3,(H,26,29) CPGVFFIAFKTJQY-UHFFFAOYSA-N 50052573 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL26426 D(2) dopamine receptor Rattus norvegicus 448 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740968 103949425 CHEMBL26426 ZINC13757312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777111 COc1cccc2C(CCCc12)NC(=O)CN1CCN(CC1)c1ccccc1 InChI=1S/C23H29N3O2/c1-28-22-12-6-9-19-20(22)10-5-11-21(19)24-23(27)17-25-13-15-26(16-14-25)18-7-3-2-4-8-18/h2-4,6-9,12,21H,5,10-11,13-17H2,1H3,(H,24,27) ZFSPQLXKVJSAMN-UHFFFAOYSA-N 50052571 CHEMBL109263::N-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-2-(4-phenyl-piperazin-1-yl)-acetamide D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10714760 103949423 CHEMBL109263 ZINC13757363 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777117 COc1cccc2C(CCCc12)NCCN1CCN(CC1)c1ccccn1 InChI=1S/C22H30N4O/c1-27-21-9-5-6-18-19(21)7-4-8-20(18)23-12-13-25-14-16-26(17-15-25)22-10-2-3-11-24-22/h2-3,5-6,9-11,20,23H,4,7-8,12-17H2,1H3 WMEXYJKBXVWCOJ-UHFFFAOYSA-N 50052559 (5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-[2-(4-pyridin-2-yl-piperazin-1-yl)-ethyl]-amine::CHEMBL108245 D(2) dopamine receptor Rattus norvegicus 1850 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052559 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052559&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10474096 103949411 CHEMBL108245 ZINC22859272 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777120 COc1cccc2C(CCCc12)NCCN1CCN(CC1)c1ccccc1 InChI=1S/C23H31N3O/c1-27-23-12-6-9-20-21(23)10-5-11-22(20)24-13-14-25-15-17-26(18-16-25)19-7-3-2-4-8-19/h2-4,6-9,12,22,24H,5,10-11,13-18H2,1H3 XGTOSEODMLDCBR-UHFFFAOYSA-N 50052570 (5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-[2-(4-phenyl-piperazin-1-yl)-ethyl]-amine::CHEMBL325092 D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522878 103949422 CHEMBL325092 ZINC22938374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777129 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 5.2 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777130 COc1cccc2C(CCCc12)NC(=O)CCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H33N3O3/c1-30-23-12-6-7-19-20(23)8-5-9-21(19)26-25(29)13-14-27-15-17-28(18-16-27)22-10-3-4-11-24(22)31-2/h3-4,6-7,10-12,21H,5,8-9,13-18H2,1-2H3,(H,26,29) HGOXUQUWFDSTAA-UHFFFAOYSA-N 50052563 3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-N-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propionamide::CHEMBL28063::N-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-3-(4-(2-methoxyphenyl)piperazin-1-yl)propanamide D(2) dopamine receptor Rattus norvegicus 761 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052563&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740969 103949415 CHEMBL28063 ZINC13586504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777131 COc1cccc2C(CCCc12)NC(=O)CCN1CCN(CC1)c1ccccc1 InChI=1S/C24H31N3O2/c1-29-23-12-6-9-20-21(23)10-5-11-22(20)25-24(28)13-14-26-15-17-27(18-16-26)19-7-3-2-4-8-19/h2-4,6-9,12,22H,5,10-11,13-18H2,1H3,(H,25,28) YQVQIDUJLONEHJ-UHFFFAOYSA-N 50052574 CHEMBL108858::N-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-3-(4-phenyl-piperazin-1-yl)-propionamide D(2) dopamine receptor Rattus norvegicus 2970 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10500792 103949426 CHEMBL108858 ZINC13757365 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777133 COc1cccc2C(CCCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C26H36N2O2/c1-29-25-15-8-11-22-21(10-7-12-23(22)25)9-5-6-16-27-17-19-28(20-18-27)24-13-3-4-14-26(24)30-2/h3-4,8,11,13-15,21H,5-7,9-10,12,16-20H2,1-2H3 FKAHRAYTSLFRRL-UHFFFAOYSA-N 50033835 1-(2-Methoxy-phenyl)-4-[4-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperazine::CHEMBL28209 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10001519 103942083 CHEMBL28209 ZINC13740680 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777135 COc1cccc2C(CCCc12)C(=O)N(C)CCCN1CCN(CC1)c1ccccc1 InChI=1S/C26H35N3O2/c1-27(26(30)24-13-6-12-23-22(24)11-7-14-25(23)31-2)15-8-16-28-17-19-29(20-18-28)21-9-4-3-5-10-21/h3-5,7,9-11,14,24H,6,8,12-13,15-20H2,1-2H3 RLCDLDPMLOPMDM-UHFFFAOYSA-N 50052562 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid methyl-[3-(4-phenyl-piperazin-1-yl)-propyl]-amide::CHEMBL108942 D(2) dopamine receptor Rattus norvegicus 594 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052562 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052562&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574209 103949414 CHEMBL108942 ZINC13757337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777136 COc1cccc2C(CCCc12)C(=O)N(C)CCN1CCN(CC1)c1ccccc1 InChI=1S/C25H33N3O2/c1-26(14-15-27-16-18-28(19-17-27)20-8-4-3-5-9-20)25(29)23-12-6-11-22-21(23)10-7-13-24(22)30-2/h3-5,7-10,13,23H,6,11-12,14-19H2,1-2H3 PAWFPAAEGFXNSU-UHFFFAOYSA-N 50052566 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid methyl-[2-(4-phenyl-piperazin-1-yl)-ethyl]-amide::CHEMBL325565 D(2) dopamine receptor Rattus norvegicus 882 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645098 103949418 CHEMBL325565 ZINC13757329 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777142 COc1cccc2C(CNCCN3CCN(CC3)c3ccccc3)CCCc12 InChI=1S/C24H33N3O/c1-28-24-12-6-10-22-20(7-5-11-23(22)24)19-25-13-14-26-15-17-27(18-16-26)21-8-3-2-4-9-21/h2-4,6,8-10,12,20,25H,5,7,11,13-19H2,1H3 LARIVMVEHPBTKT-UHFFFAOYSA-N 50052575 (5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-[2-(4-phenyl-piperazin-1-yl)-ethyl]-amine::CHEMBL107921 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10785980 103949427 CHEMBL107921 ZINC22938368 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777143 COc1cccc2C(CCCc12)N(C)CCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H35N3O2/c1-26(22-11-6-9-21-20(22)8-7-13-24(21)29-2)14-15-27-16-18-28(19-17-27)23-10-4-5-12-25(23)30-3/h4-5,7-8,10,12-13,22H,6,9,11,14-19H2,1-3H3 HLQOTKYQYOTGSD-UHFFFAOYSA-N 50052561 CHEMBL326017::{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-methyl-amine D(2) dopamine receptor Rattus norvegicus 73 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052561 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052561&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10525589 103949413 CHEMBL326017 ZINC22938383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777145 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777146 COc1cccc2C(CCCc12)C(=O)NCCCN1CCN(CC1)c1ccccc1 InChI=1S/C25H33N3O2/c1-30-24-13-6-10-21-22(24)11-5-12-23(21)25(29)26-14-7-15-27-16-18-28(19-17-27)20-8-3-2-4-9-20/h2-4,6,8-10,13,23H,5,7,11-12,14-19H2,1H3,(H,26,29) GQMJKOKDIZUSHW-UHFFFAOYSA-N 50052564 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid [3-(4-phenyl-piperazin-1-yl)-propyl]-amide::CHEMBL111760 D(2) dopamine receptor Rattus norvegicus 783 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10716365 103949416 CHEMBL111760 ZINC13757320 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777153 COc1cccc2C(CCCc12)NCCN1CCN(CC1)c1ccccc1OC InChI=1S/C24H33N3O2/c1-28-23-12-6-7-19-20(23)8-5-9-21(19)25-13-14-26-15-17-27(18-16-26)22-10-3-4-11-24(22)29-2/h3-4,6-7,10-12,21,25H,5,8-9,13-18H2,1-2H3 FVDGLILSFMGSJG-UHFFFAOYSA-N 50033847 CHEMBL108241::{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine D(2) dopamine receptor Rattus norvegicus 380 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10453320 103942095 CHEMBL108241 ZINC22937544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777155 COc1cccc2C(CCCc12)C(=O)NCCN1CCN(CC1)c1ccccc1 InChI=1S/C24H31N3O2/c1-29-23-12-6-9-20-21(23)10-5-11-22(20)24(28)25-13-14-26-15-17-27(18-16-26)19-7-3-2-4-8-19/h2-4,6-9,12,22H,5,10-11,13-18H2,1H3,(H,25,28) ZNLVNNSCBPOHJX-UHFFFAOYSA-N 50052572 5-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid [2-(4-phenyl-piperazin-1-yl)-ethyl]-amide::CHEMBL320587 D(2) dopamine receptor Rattus norvegicus 4040 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10763158 103949424 CHEMBL320587 ZINC12356288 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777160 COc1cccc2C(CCCc12)NCCCN1CCN(CC1)c1ccccc1OC InChI=1S/C25H35N3O2/c1-29-24-13-6-8-20-21(24)9-5-10-22(20)26-14-7-15-27-16-18-28(19-17-27)23-11-3-4-12-25(23)30-2/h3-4,6,8,11-13,22,26H,5,7,9-10,14-19H2,1-2H3 JQDKIHJGQVYOCG-UHFFFAOYSA-N 50052569 CHEMBL107486::{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-amine D(2) dopamine receptor Rattus norvegicus 1060 ChEMBL 10.1021/jm960087s 10.7270/Q2GM87ZN 8759642 Perrone, R; Berardi, F; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669248 103949421 CHEMBL107486 ZINC13757354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780727 CCCc1cc2CN[C@H]3CCc4cc(O)c(O)cc4[C@@H]3c2s1 InChI=1S/C18H21NO2S/c1-2-3-12-6-11-9-19-14-5-4-10-7-15(20)16(21)8-13(10)17(14)18(11)22-12/h6-8,14,17,19-21H,2-5,9H2,1H3/t14-,17-/m0/s1 PAUUVJVIWWLQGB-YOEHRIQHSA-N 50057841 (5aS,11bS)-2-Propyl-4,5,5a,6,7,11b-hexahydro-1-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL40667 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057841&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10710466 103953820 CHEMBL40667 ZINC13762006 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780729 CC(C)c1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C18H21NO2S/c1-9(2)16-7-12-17(22-16)8-19-13-4-3-10-5-14(20)15(21)6-11(10)18(12)13/h5-7,9,13,18-21H,3-4,8H2,1-2H3/t13-,18+/m0/s1 XCVRPMHYLBIKRT-SCLBCKFNSA-N 50057857 (5aS,11bR)-2-Isopropyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL446350 D(2) dopamine receptor Rattus norvegicus 1720 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10519435 103953836 CHEMBL446350 ZINC13762028 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780731 Oc1cc2CC[C@@H]3NCc4sc(cc4[C@H]3c2cc1O)C1CCCCC1 InChI=1S/C21H25NO2S/c23-17-8-13-6-7-16-21(14(13)9-18(17)24)15-10-19(25-20(15)11-22-16)12-4-2-1-3-5-12/h8-10,12,16,21-24H,1-7,11H2/t16-,21+/m0/s1 AWCWQIFJWRNJCA-HRAATJIYSA-N 50057835 (5aS,11bR)-2-Cyclohexyl-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL290149 D(2) dopamine receptor Rattus norvegicus 3110 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10546131 103953814 CHEMBL290149 ZINC13762034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780732 CC(C)CCc1cc2[C@@H]3[C@H](CCc4cc(O)c(O)cc34)NCc2s1 InChI=1S/C20H25NO2S/c1-11(2)3-5-13-8-15-19(24-13)10-21-16-6-4-12-7-17(22)18(23)9-14(12)20(15)16/h7-9,11,16,20-23H,3-6,10H2,1-2H3/t16-,20+/m0/s1 BTLAJQAIHGUMKQ-OXJNMPFZSA-N 50057854 (5aS,11bR)-2-(3-Methyl-butyl)-4,5,5a,6,7,11b-hexahydro-3-thia-5-aza-cyclopenta[c]phenanthrene-9,10-diol::CHEMBL41809 D(2) dopamine receptor Rattus norvegicus 1760 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10831251 103953833 CHEMBL41809 ZINC13762032 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50780737 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)C12CC3CC(CC(C3)C1)C2 InChI=1S/C20H27NO3/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20/h1-2,11-13,17-18,22-23H,3-10,21H2/t11?,12?,13?,17-,18-,20?/m0/s1 QLJOSZATCBCBDR-DFKUFRTHSA-N 50033116 (1R,3S)-3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol::A-77636::CHEMBL291143::cid_6603703 D(2) dopamine receptor Rattus norvegicus 1800 ChEMBL 10.1021/jm970038v 10.7270/Q2Z89D2B 9171869 Michaelides, MR; Hong, Y; DiDomenico, S; Bayburt, EK; Asin, KE; Britton, DR; Lin, CW; Shiosaki, K Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033116&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G3O 7CKX 6603703 103941457 64080 CHEMBL291143 ZINC03782517 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765865 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccc(F)cc2)CC1 InChI=1S/C20H23ClFN3O2/c1-27-19-11-18(23)17(21)10-16(19)20(26)24-15-6-8-25(9-7-15)12-13-2-4-14(22)5-3-13/h2-5,10-11,15H,6-9,12,23H2,1H3,(H,24,26) HKDIGEWWDHALIS-UHFFFAOYSA-N 50042726 4-Amino-5-chloro-N-[1-(4-fluoro-benzyl)-piperidin-4-yl]-2-methoxy-benzamide::CHEMBL125237 D(2) dopamine receptor Rattus norvegicus 0.950000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127887 103974291 CHEMBL125237 ZINC05998832 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765875 COc1cc(Br)cc(C(=O)NC2CCN(Cc3ccccc3)CC2)c1OC InChI=1S/C21H25BrN2O3/c1-26-19-13-16(22)12-18(20(19)27-2)21(25)23-17-8-10-24(11-9-17)14-15-6-4-3-5-7-15/h3-7,12-13,17H,8-11,14H2,1-2H3,(H,23,25) SZYKUFQJFLQMPU-UHFFFAOYSA-N 50007514 CHEMBL75842::N-(1-Benzyl-piperidin-4-yl)-5-bromo-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.310000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15167710 103920789 CHEMBL75842 ZINC13820634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765878 COc1cc(Br)cc(C(=O)NC2CCN(Cc3ccc(F)cc3)CC2)c1OC InChI=1S/C21H24BrFN2O3/c1-27-19-12-15(22)11-18(20(19)28-2)21(26)24-17-7-9-25(10-8-17)13-14-3-5-16(23)6-4-14/h3-6,11-12,17H,7-10,13H2,1-2H3,(H,24,26) ZDZVACBBQOTFIS-UHFFFAOYSA-N 50042731 5-Bromo-N-[1-(4-fluoro-benzyl)-piperidin-4-yl]-2,3-dimethoxy-benzamide::CHEMBL124612 D(2) dopamine receptor Rattus norvegicus 0.070000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042731&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10003936 103974296 CHEMBL124612 ZINC13834040 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765879 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) BVPWJMCABCPUQY-UHFFFAOYSA-N 50132693 4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide(Clebopride)::4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide::CHEMBL325109::Clebopride D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2780 104023670 CHEMBL325109 ZINC00608261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765883 COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCCC(C1)N2Cc1ccccc1 InChI=1S/C23H28ClN3O2/c1-29-22-13-21(25)20(24)12-19(22)23(28)26-16-10-17-8-5-9-18(11-16)27(17)14-15-6-3-2-4-7-15/h2-4,6-7,12-13,16-18H,5,8-11,14,25H2,1H3,(H,26,28) BUPWFKLTAPZHIE-UHFFFAOYSA-N 50042732 4-Amino-N-(9-benzyl-9-aza-bicyclo[3.3.1]non-3-yl)-5-chloro-2-methoxy-benzamide::BRL-26175::CHEMBL122533 D(2) dopamine receptor Rattus norvegicus 0.036000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042732&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44348012 103974297 CHEMBL122533 ZINC13834041 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765886 COc1cccc(C(=O)NC2CCN(Cc3ccccc3)CC2)c1OC InChI=1S/C21H26N2O3/c1-25-19-10-6-9-18(20(19)26-2)21(24)22-17-11-13-23(14-12-17)15-16-7-4-3-5-8-16/h3-10,17H,11-15H2,1-2H3,(H,22,24) CFOLDWHTVLAWTI-UHFFFAOYSA-N 50007525 CHEMBL123282::N-(1-Benzyl-piperidin-4-yl)-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.630000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13314232 103920800 CHEMBL123282 ZINC13820638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765889 COc1cc(N)c(Cl)cc1C(=O)N1CC2CCCC(C1)N2Cc1ccccc1 InChI=1S/C22H26ClN3O2/c1-28-21-11-20(24)19(23)10-18(21)22(27)25-13-16-8-5-9-17(14-25)26(16)12-15-6-3-2-4-7-15/h2-4,6-7,10-11,16-17H,5,8-9,12-14,24H2,1H3 FHNNETCMANTKTB-UHFFFAOYSA-N 50042733 (9-Benzyl-3,9-diaza-bicyclo[3.3.1]non-3-yl)-(5-bromo-2,3-dimethoxy-phenyl)-methanone::CHEMBL122445 D(2) dopamine receptor Rattus norvegicus 0.033000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042733&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44348010 103974298 CHEMBL122445 ZINC27203483 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765892 COc1cc(Br)cc(C(=O)NC2CC3CCCC(C2)N3Cc2ccc(F)cc2)c1OC InChI=1S/C24H28BrFN2O3/c1-30-22-11-16(25)10-21(23(22)31-2)24(29)27-18-12-19-4-3-5-20(13-18)28(19)14-15-6-8-17(26)9-7-15/h6-11,18-20H,3-5,12-14H2,1-2H3,(H,27,29) LPJUXGCWOZCVCP-UHFFFAOYSA-N 50042730 4-Amino-5-chloro-N-[5-(4-fluoro-benzyl)-octahydro-quinolizin-2-yl]-2-methoxy-benzamide::CHEMBL2112608 D(2) dopamine receptor Rattus norvegicus 0.020000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042730&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23277249 103974295 CHEMBL2112608 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765895 COc1cccc(C(=O)NC2CCN(Cc3ccc(F)cc3)CC2)c1OC InChI=1S/C21H25FN2O3/c1-26-19-5-3-4-18(20(19)27-2)21(25)23-17-10-12-24(13-11-17)14-15-6-8-16(22)9-7-15/h3-9,17H,10-14H2,1-2H3,(H,23,25) KSZBKOKLZQIWFH-UHFFFAOYSA-N 50042725 CHEMBL340471::N-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.380000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042725&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134002 103974290 CHEMBL340471 ZINC06019118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50765896 COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CC2CCCC1N2Cc1ccc(F)cc1 InChI=1S/C22H25ClFN3O2/c1-29-21-11-18(25)17(23)10-16(21)22(28)26-19-9-15-3-2-4-20(19)27(15)12-13-5-7-14(24)8-6-13/h5-8,10-11,15,19-20H,2-4,9,12,25H2,1H3,(H,26,28)/t15?,19-,20?/m0/s1 KBMHZDMOELXKBL-YHDJDMAPSA-N 50368742 CHEMBL1169525 D(2) dopamine receptor Rattus norvegicus 0.017000 ChEMBL 10.1021/jm00075a028 10.7270/Q2MK6DH1 8246241 Mach, RH; Luedtke, RR; Unsworth, CD; Boundy, VA; Nowak, PA; Scripko, JG; Elder, ST; Jackson, JR; Hoffman, PL; Evora, PH University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368742&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 49799934 160847844 CHEMBL1169525 ZINC53296236 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771630 COc1ccccc1C1CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C24H30N2O/c1-27-24-12-5-3-10-22(24)19-13-16-26(17-14-19)15-7-6-8-20-18-25-23-11-4-2-9-21(20)23/h2-5,9-12,18-19,25H,6-8,13-17H2,1H3 NKPDKJVQROXIIC-UHFFFAOYSA-N 50035096 3-{4-[4-(2-Methoxy-phenyl)-piperidin-1-yl]-butyl}-1H-indole::CHEMBL61747 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035096&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10338706 103943144 CHEMBL61747 ZINC13741505 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771635 Fc1ccc(cc1)C1CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H27FN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-11,17,19,25H,3-5,12-16H2 MNTZHLHHOJLERY-UHFFFAOYSA-N 50035108 3-{4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-butyl}-1H-indole::CHEMBL60267 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035108&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11725456 103943156 CHEMBL60267 ZINC13741507 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771641 Fc1ccc(cc1)N1CCN(CCCCc2cn(-c3ccc(F)cc3)c3ccccc23)CC1 InChI=1S/C28H29F2N3/c29-23-8-12-25(13-9-23)32-19-17-31(18-20-32)16-4-3-5-22-21-33(26-14-10-24(30)11-15-26)28-7-2-1-6-27(22)28/h1-2,6-15,21H,3-5,16-20H2 NSJANYUTRNGXRW-UHFFFAOYSA-N 50035104 1-(4-Fluoro-phenyl)-3-{4-[4-(4-fluoro-phenyl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL416506 D(2) dopamine receptor Rattus norvegicus 3000 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035104&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10252949 103943152 CHEMBL416506 ZINC13741508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771649 Fc1ccc(cc1)N1CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C22H26FN3/c23-19-8-10-20(11-9-19)26-15-13-25(14-16-26)12-4-3-5-18-17-24-22-7-2-1-6-21(18)22/h1-2,6-11,17,24H,3-5,12-16H2 PTKJETUJAPZSQR-UHFFFAOYSA-N 50035099 3-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-1H-indole::CHEMBL279586 D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035099&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10450613 103943147 CHEMBL279586 ZINC13741506 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771656 Fc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H25FN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-12,17,25H,3-5,13-16H2 WOQPWODQIGGKJL-UHFFFAOYSA-N 50002171 3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL64344 D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10452645 103916477 CHEMBL64344 ZINC13728583 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771662 Fc1ccc(cc1)C(=O)CC1CCN(CC2CC2)CC1 InChI=1S/C17H22FNO/c18-16-5-3-15(4-6-16)17(20)11-13-7-9-19(10-8-13)12-14-1-2-14/h3-6,13-14H,1-2,7-12H2 KWRMWQDKOGFMKP-UHFFFAOYSA-N 50002218 2-(1-Cyclopropylmethyl-piperidin-4-yl)-1-(4-fluoro-phenyl)-ethanone; hydrobromide::CHEMBL42228::CHEMBL543412 D(2) dopamine receptor Rattus norvegicus 640 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002218&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 121968 103916524 CHEMBL543412CHEMBL42228 ZINC00004902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771664 C(CCc1c[nH]c2ccccc12)CN1CCC(CC1)c1ccccc1 InChI=1S/C23H28N2/c1-2-8-19(9-3-1)20-13-16-25(17-14-20)15-7-6-10-21-18-24-23-12-5-4-11-22(21)23/h1-5,8-9,11-12,18,20,24H,6-7,10,13-17H2 JHLJHQQFPBTTJE-UHFFFAOYSA-N 50002164 3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole::CHEMBL59335 D(2) dopamine receptor Rattus norvegicus 45 ChEMBL 10.1021/jm00011a019 10.7270/Q2SJ1M8P 7783131 Perregaard, J; Moltzen, EK; Meier, E; Sanchez, C H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002164&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10451707 103916470 CHEMBL59335 ZINC13728601 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791439 COc1ccc(CCN)cc1OCCc1ccccc1 InChI=1S/C17H21NO2/c1-19-16-8-7-15(9-11-18)13-17(16)20-12-10-14-5-3-2-4-6-14/h2-8,13H,9-12,18H2,1H3 PHZKTCBQEYKDQX-UHFFFAOYSA-N 50074833 2-(4-Methoxy-3-phenethyloxy-phenyl)-ethylamine; hydrochloride::CHEMBL542784 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074833&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10683536 103968025 CHEMBL542784 ZINC11860194 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791441 CCCNCCc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C20H27NO2/c1-3-13-21-14-11-18-9-10-19(22-2)20(16-18)23-15-12-17-7-5-4-6-8-17/h4-10,16,21H,3,11-15H2,1-2H3 AEQMNSOSQSZZIB-UHFFFAOYSA-N 50074857 CHEMBL542786::[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-propyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10710332 103968049 CHEMBL542786 ZINC13795850 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791442 COc1ccc(CCN2CCCC2)cc1OCCc1ccccc1 InChI=1S/C21H27NO2/c1-23-20-10-9-19(11-15-22-13-5-6-14-22)17-21(20)24-16-12-18-7-3-2-4-8-18/h2-4,7-10,17H,5-6,11-16H2,1H3 AFGQADKELTYBPU-UHFFFAOYSA-N 50074855 1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-pyrrolidine; compound with oxalic acid::CHEMBL11311 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10496297 103968047 CHEMBL11311 ZINC13795768 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771848 CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C27H37N3O3/c1-4-11-29(12-5-6-13-30-24(32)15-27(2,3)16-25(30)33)21-9-7-19-8-10-23-26(22(19)14-21)20(18-31)17-28-23/h8,10,17-18,21,28H,4-7,9,11-16H2,1-3H3/t21-/m1/s1 NLXASJVETPACMT-OAQYLSRUSA-N 50369016 CHEMBL1788198 D(2) dopamine receptor Rattus norvegicus 62 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369016&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10003971 160848118 CHEMBL1788198 ZINC13741766 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771850 CCCN(C)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C16H22N2/c1-3-10-18(2)13-6-4-12-5-7-16-14(8-9-17-16)15(12)11-13/h5,7-9,13,17H,3-4,6,10-11H2,1-2H3 WSLVLAZYRCUHNL-UHFFFAOYSA-N 50035340 CHEMBL71409::Methyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10243466 103943366 CHEMBL71409 ZINC13741731 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779003 COc1cccc2\C(CCCc12)=C\CCN1CCN(CC1)c1ccccc1 InChI=1S/C24H30N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h2-4,6,9-12,14H,5,7-8,13,15-19H2,1H3/b20-9+ VKOJWPSHQQXTMQ-AWQFTUOYSA-N 50054992 1-{3-[5-Methoxy-3,4-dihydro-2H-naphthalen-(1E)-ylidene]-propyl}-4-phenyl-piperazine::CHEMBL147440 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054992&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44363591 103951566 CHEMBL147440 ZINC13760535 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779004 COc1ccc2CCC(CCN3CCN(CC3)c3ccccc3)Cc2c1 InChI=1S/C23H30N2O/c1-26-23-10-9-20-8-7-19(17-21(20)18-23)11-12-24-13-15-25(16-14-24)22-5-3-2-4-6-22/h2-6,9-10,18-19H,7-8,11-17H2,1H3 VHTJFANFSJSTEZ-UHFFFAOYSA-N 50054990 1-[2-(7-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-ethyl]-4-phenyl-piperazine::CHEMBL144445 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054990&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10617866 103951564 CHEMBL144445 ZINC13760546 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779005 COc1cccc2C(CCCN3CCN(CC3)c3ccccn3)CCCc12 InChI=1S/C23H31N3O/c1-27-22-11-5-9-20-19(7-4-10-21(20)22)8-6-14-25-15-17-26(18-16-25)23-12-2-3-13-24-23/h2-3,5,9,11-13,19H,4,6-8,10,14-18H2,1H3 KKPMYWNQZNRGIK-UHFFFAOYSA-N 50033852 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-pyridin-2-yl-piperazine::CHEMBL444590 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10474042 103942100 CHEMBL444590 ZINC13470658 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779009 COc1ccc2C=C(CCN3CCN(CC3)c3ccccc3)CCc2c1 InChI=1S/C23H28N2O/c1-26-23-10-9-20-17-19(7-8-21(20)18-23)11-12-24-13-15-25(16-14-24)22-5-3-2-4-6-22/h2-6,9-10,17-18H,7-8,11-16H2,1H3 HTCBQRGEAMMAAA-UHFFFAOYSA-N 50054996 1-[2-(6-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl]-4-phenyl-piperazine::CHEMBL357176 D(2) dopamine receptor Rattus norvegicus 170 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10807686 103951570 CHEMBL357176 ZINC13760539 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779010 COc1cccc2CCCC(CCCN3CCN(CC3)c3ccccc3)c12 InChI=1S/C24H32N2O/c1-27-23-14-6-10-20-8-5-9-21(24(20)23)11-7-15-25-16-18-26(19-17-25)22-12-3-2-4-13-22/h2-4,6,10,12-14,21H,5,7-9,11,15-19H2,1H3 ULGUNJHZINAMQR-UHFFFAOYSA-N 50054995 1-[3-(8-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL145432 D(2) dopamine receptor Rattus norvegicus 62 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10713840 103951569 CHEMBL145432 ZINC13760534 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779018 COc1cccc2CC(CCN3CCN(CC3)c3ccccc3)CCc12 InChI=1S/C23H30N2O/c1-26-23-9-5-6-20-18-19(10-11-22(20)23)12-13-24-14-16-25(17-15-24)21-7-3-2-4-8-21/h2-9,19H,10-18H2,1H3 YSEIEOUPJDUMFS-UHFFFAOYSA-N 50054993 1-[2-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-ethyl]-4-phenyl-piperazine::CHEMBL343432 D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10617865 103951567 CHEMBL343432 ZINC13760542 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779023 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3OC)CCCc12 InChI=1S/C25H34N2O2/c1-28-24-14-6-10-21-20(8-5-11-22(21)24)9-7-15-26-16-18-27(19-17-26)23-12-3-4-13-25(23)29-2/h3-4,6,10,12-14,20H,5,7-9,11,15-19H2,1-2H3 INGWKGCHJJYQIB-UHFFFAOYSA-N 50033839 1-(2-Methoxy-phenyl)-4-[3-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperazine::CHEMBL26929 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10385977 103942087 CHEMBL26929 ZINC13740674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779038 COc1ccc2CC(CCN3CCN(CC3)c3ccccc3)CCc2c1 InChI=1S/C23H30N2O/c1-26-23-10-9-20-17-19(7-8-21(20)18-23)11-12-24-13-15-25(16-14-24)22-5-3-2-4-6-22/h2-6,9-10,18-19H,7-8,11-17H2,1H3 JDVVNXKPGXETDT-UHFFFAOYSA-N 50054999 1-[2-(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-ethyl]-4-phenyl-piperazine::CHEMBL143728 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054999&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10760347 103951573 CHEMBL143728 ZINC13760544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779040 COc1cccc2C(CCN3CCN(CC3)c3ccccc3)CCCc12 InChI=1S/C23H30N2O/c1-26-23-12-6-10-21-19(7-5-11-22(21)23)13-14-24-15-17-25(18-16-24)20-8-3-2-4-9-20/h2-4,6,8-10,12,19H,5,7,11,13-18H2,1H3 JAVQDOJQALZLNZ-UHFFFAOYSA-N 50054991 1-[2-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-ethyl]-4-phenyl-piperazine::CHEMBL144417 D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054991&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10569886 103951565 CHEMBL144417 ZINC13760530 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779042 COc1cccc2C=C(CCN3CCN(CC3)c3ccccc3)CCc12 InChI=1S/C23H28N2O/c1-26-23-9-5-6-20-18-19(10-11-22(20)23)12-13-24-14-16-25(17-15-24)21-7-3-2-4-8-21/h2-9,18H,10-17H2,1H3 CQXXOUAHPSOSEL-UHFFFAOYSA-N 50055000 1-[2-(5-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl]-4-phenyl-piperazine::CHEMBL147387 D(2) dopamine receptor Rattus norvegicus 276 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055000&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10760170 103951574 CHEMBL147387 ZINC13760538 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779043 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3)=CCCc12 InChI=1S/C24H30N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h2-4,6,8,10-12,14H,5,7,9,13,15-19H2,1H3 XOBUAHLUTFRWNA-UHFFFAOYSA-N 50033850 1-[3-(5-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL148055 D(2) dopamine receptor Rattus norvegicus 303 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033850&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10021562 103942098 CHEMBL148055 ZINC13733303 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50784803 COc1ccc(CCCCNCCOc2cc(C)cc3CCCOc23)cc1 InChI=1S/C23H31NO3/c1-18-16-20-7-5-14-27-23(20)22(17-18)26-15-13-24-12-4-3-6-19-8-10-21(25-2)11-9-19/h8-11,16-17,24H,3-7,12-15H2,1-2H3 YEXMXGRLJXAVKY-UHFFFAOYSA-N 50057431 CHEMBL21475::[4-(4-Methoxy-phenyl)-butyl]-[2-(6-methyl-chroman-8-yloxy)-ethyl]-amine D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809124 103953483 CHEMBL21475 ZINC13761776 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50784804 COc1ccc(CCCCNCCOc2c(F)ccc3CCCOc23)cc1 InChI=1S/C22H28FNO3/c1-25-19-10-7-17(8-11-19)5-2-3-13-24-14-16-27-22-20(23)12-9-18-6-4-15-26-21(18)22/h7-12,24H,2-6,13-16H2,1H3 TVNIVNPKPOOYNO-UHFFFAOYSA-N 50057429 CHEMBL22328::[2-(7-Fluoro-chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057429&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809366 103953481 CHEMBL22328 ZINC13761782 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50784810 COc1ccc(CCCCNCCOc2cc(Cl)cc3CCCOc23)cc1 InChI=1S/C22H28ClNO3/c1-25-20-9-7-17(8-10-20)5-2-3-11-24-12-14-26-21-16-19(23)15-18-6-4-13-27-22(18)21/h7-10,15-16,24H,2-6,11-14H2,1H3 AZTBUJYRTXIDPA-UHFFFAOYSA-N 50057428 CHEMBL22682::[2-(6-Chloro-chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 0.49 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057428&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977670 103953480 CHEMBL22682 ZINC13761778 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50784814 CCCN(CCC)[C@H]1CCc2c(F)ccc(O)c2C1 InChI=1S/C16H24FNO/c1-3-9-18(10-4-2)12-5-6-13-14(11-12)16(19)8-7-15(13)17/h7-8,12,19H,3-6,9-11H2,1-2H3/t12-/m0/s1 FNKBVTBXFLSTPB-LBPRGKRZSA-N 50013019 (S)-7-(dipropylamino)-4-fluoro-5,6,7,8-tetrahydronaphthalen-1-ol::(S)-7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-UH-301::7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol::7-Dipropylamino-4-fluoro-5,6,7,8-tetrahydro-naphthalen-1-ol ((S)-UH301)::CHEMBL22778::UH-301 D(2) dopamine receptor Rattus norvegicus 614 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122187 103925253 CHEMBL22778 61 C11698 ZINC03874895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50784816 COc1ccccc1N1CCN(C[C@@H](C(=O)NC(C)(C)C)c2ccccc2)CC1 InChI=1S/C24H33N3O2/c1-24(2,3)25-23(28)20(19-10-6-5-7-11-19)18-26-14-16-27(17-15-26)21-12-8-9-13-22(21)29-4/h5-13,20H,14-18H2,1-4H3,(H,25,28)/t20-/m1/s1 UMTDAKAAYOXIKU-HXUWFJFHSA-N 50047471 (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)piperazin-1-yl)-2-phenylpropanamide::CHEMBL38288::N-tert-Butyl-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-2-phenyl-propionamide::WAY-100135 D(2) dopamine receptor Rattus norvegicus 176 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50047471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50047471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604840 103978073 CHEMBL38288 126 ZINC52957106 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50784817 COc1ccc(CCCCNCCOc2cccc3CCCOc23)cc1 InChI=1S/C22H29NO3/c1-24-20-12-10-18(11-13-20)6-2-3-14-23-15-17-25-21-9-4-7-19-8-5-16-26-22(19)21/h4,7,9-13,23H,2-3,5-6,8,14-17H2,1H3 RHNWSBLMCVFMKW-UHFFFAOYSA-N 50057432 CHEMBL25215::[2-(Chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 0.58 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057432&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10522191 103953484 CHEMBL25215 ZINC13761775 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50784818 COc1ccc(CCCCNCCOc2cc(OC)cc3CCCOc23)cc1 InChI=1S/C23H31NO4/c1-25-20-10-8-18(9-11-20)6-3-4-12-24-13-15-27-22-17-21(26-2)16-19-7-5-14-28-23(19)22/h8-11,16-17,24H,3-7,12-15H2,1-2H3 USBMLMLDKIBGBI-UHFFFAOYSA-N 50057435 CHEMBL25663::[2-(6-Methoxy-chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057435 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057435&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10643819 103953487 CHEMBL25663 ZINC13761779 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50784819 COc1ccc(CCCCNCCOc2ccc(F)c3CCCOc23)cc1 InChI=1S/C22H28FNO3/c1-25-18-9-7-17(8-10-18)5-2-3-13-24-14-16-26-21-12-11-20(23)19-6-4-15-27-22(19)21/h7-12,24H,2-6,13-16H2,1H3 BEDFAHBKPZRACP-UHFFFAOYSA-N 50057433 CHEMBL278806::[2-(5-Fluoro-chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 3.5 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9976625 103953485 CHEMBL278806 ZINC13761781 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50784822 COc1ccc(CCCCNCCOc2cc(O)cc3CCCOc23)cc1 InChI=1S/C22H29NO4/c1-25-20-9-7-17(8-10-20)5-2-3-11-23-12-14-26-21-16-19(24)15-18-6-4-13-27-22(18)21/h7-10,15-16,23-24H,2-6,11-14H2,1H3 ZGICPBLSOPGEDI-UHFFFAOYSA-N 50057434 8-{2-[4-(4-Methoxy-phenyl)-butylamino]-ethoxy}-chroman-6-ol::CHEMBL22802 D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057434 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057434&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10499477 103953486 CHEMBL22802 ZINC13761780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50784823 COc1ccc(CCCCNCCOc2cc(F)cc3CCCOc23)cc1 InChI=1S/C22H28FNO3/c1-25-20-9-7-17(8-10-20)5-2-3-11-24-12-14-26-21-16-19(23)15-18-6-4-13-27-22(18)21/h7-10,15-16,24H,2-6,11-14H2,1H3 ZRVOLZXRGXGYEH-UHFFFAOYSA-N 50057436 CHEMBL25213::[2-(6-Fluoro-chroman-8-yloxy)-ethyl]-[4-(4-methoxy-phenyl)-butyl]-amine D(2) dopamine receptor Rattus norvegicus 0.26 ChEMBL 10.1021/jm960760d 10.7270/Q20R9Q26 9111299 Yasunaga, T; Naito, R; Kontani, T; Tsukamoto, S; Nomura, T; Yamaguchi, T; Mase, T Yamanouchi Pharmaceutical Company, Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057436 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057436&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11740080 103953488 CHEMBL25213 ZINC13761777 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791450 CCCNC(CC)Cc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C22H31NO2/c1-4-14-23-20(5-2)16-19-11-12-21(24-3)22(17-19)25-15-13-18-9-7-6-8-10-18/h6-12,17,20,23H,4-5,13-16H2,1-3H3 PXSSCTFSGMPCKZ-UHFFFAOYSA-N 50081372 CHEMBL127899::[1-(4-Methoxy-3-phenethyloxy-benzyl)-propyl]-propyl-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081372 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081372&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10545203 103981400 CHEMBL127899 ZINC13801115 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791452 CCCN(CCC)C(CC)Cc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C25H37NO2/c1-5-16-26(17-6-2)23(7-3)19-22-13-14-24(27-4)25(20-22)28-18-15-21-11-9-8-10-12-21/h8-14,20,23H,5-7,15-19H2,1-4H3 ONKSXNPGHPILCI-UHFFFAOYSA-N 50081375 CHEMBL128717::[1-(4-Methoxy-3-phenethyloxy-benzyl)-propyl]-dipropyl-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081375&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10691389 103981403 CHEMBL128717 ZINC13801133 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791462 CCCNC(CCC)Cc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C23H33NO2/c1-4-9-21(24-15-5-2)17-20-12-13-22(25-3)23(18-20)26-16-14-19-10-7-6-8-11-19/h6-8,10-13,18,21,24H,4-5,9,14-17H2,1-3H3 ICGIQSVJOURFOI-UHFFFAOYSA-N 50081371 CHEMBL128799::[1-(4-Methoxy-3-phenethyloxy-benzyl)-butyl]-propyl-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081371&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10713214 103981399 CHEMBL128799 ZINC13801118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791463 CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3 YBLIQJGXRLZBCZ-UHFFFAOYSA-N 50170660 CHEMBL190883::CHEMBL521582::N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine::N-(4-methoxy-3-phenethoxyphenethyl)-N-propylpropan-1-amine::NE-100::[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-dipropyl-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170660&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GKY 6DK0 9841596 104057040 CHEMBL190883CHEMBL521582 6679 ZINC00598622 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791472 CCCCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)NCCC InChI=1S/C25H37NO2/c1-4-6-8-13-23(26-17-5-2)19-22-14-15-24(27-3)25(20-22)28-18-16-21-11-9-7-10-12-21/h7,9-12,14-15,20,23,26H,4-6,8,13,16-19H2,1-3H3 MJBHVLQRUJWZQC-UHFFFAOYSA-N 50081380 CHEMBL553962::[1-(4-Methoxy-3-phenethyloxy-benzyl)-hexyl]-propyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669784 103981408 CHEMBL553962 ZINC13801122 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791479 CCCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)NCCC InChI=1S/C24H35NO2/c1-4-6-12-22(25-16-5-2)18-21-13-14-23(26-3)24(19-21)27-17-15-20-10-8-7-9-11-20/h7-11,13-14,19,22,25H,4-6,12,15-18H2,1-3H3 LHWOHGLWUXQYSV-UHFFFAOYSA-N 50081369 CHEMBL128860::CHEMBL541091::[1-(4-Methoxy-3-phenethyloxy-benzyl)-pentyl]-propyl-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081369&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9999184 103981397 CHEMBL541091CHEMBL128860 ZINC13801119 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791482 CCCCCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)NCCC InChI=1S/C26H39NO2/c1-4-6-7-11-14-24(27-18-5-2)20-23-15-16-25(28-3)26(21-23)29-19-17-22-12-9-8-10-13-22/h8-10,12-13,15-16,21,24,27H,4-7,11,14,17-20H2,1-3H3 MKZMMRWGCPXHIJ-UHFFFAOYSA-N 50081367 CHEMBL339638::[1-(4-Methoxy-3-phenethyloxy-benzyl)-heptyl]-propyl-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081367 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081367&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10668517 103981395 CHEMBL339638 ZINC13801125 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791484 CCCNC(CCC(C)C)Cc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C25H37NO2/c1-5-16-26-23(13-11-20(2)3)18-22-12-14-24(27-4)25(19-22)28-17-15-21-9-7-6-8-10-21/h6-10,12,14,19-20,23,26H,5,11,13,15-18H2,1-4H3 FIQMWOKYPMJGTC-UHFFFAOYSA-N 50081366 CHEMBL540331::[1-(4-Methoxy-3-phenethyloxy-benzyl)-4-methyl-pentyl]-propyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081366&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9823429 103981394 CHEMBL540331 ZINC13801128 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791493 CCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)N(CCC)CCC InChI=1S/C26H39NO2/c1-5-11-24(27(17-6-2)18-7-3)20-23-14-15-25(28-4)26(21-23)29-19-16-22-12-9-8-10-13-22/h8-10,12-15,21,24H,5-7,11,16-20H2,1-4H3 ZYIQVNJQTOUZAX-UHFFFAOYSA-N 50081376 CHEMBL341003::[1-(4-Methoxy-3-phenethyloxy-benzyl)-butyl]-dipropyl-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081376&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10787011 103981404 CHEMBL341003 ZINC13801135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791494 CCCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)NCCC InChI=1S/C24H35NO2/c1-4-6-12-22(25-16-5-2)18-21-13-14-23(26-3)24(19-21)27-17-15-20-10-8-7-9-11-20/h7-11,13-14,19,22,25H,4-6,12,15-18H2,1-3H3 LHWOHGLWUXQYSV-UHFFFAOYSA-N 50081369 CHEMBL128860::CHEMBL541091::[1-(4-Methoxy-3-phenethyloxy-benzyl)-pentyl]-propyl-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081369 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081369&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9999184 103981397 CHEMBL541091CHEMBL128860 ZINC13801119 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50791495 CCCNC(CCC(C)C)Cc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C25H37NO2/c1-5-16-26-23(13-11-20(2)3)18-22-12-14-24(27-4)25(19-22)28-17-15-21-9-7-6-8-10-21/h6-10,12,14,19-20,23,26H,5,11,13,15-18H2,1-4H3 FIQMWOKYPMJGTC-UHFFFAOYSA-N 50081366 CHEMBL540331::[1-(4-Methoxy-3-phenethyloxy-benzyl)-4-methyl-pentyl]-propyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm990135j 10.7270/Q2PR7WQ7 10508444 Nakazato, A; Kumagai, T; Ohta, K; Chaki, S; Okuyama, S; Tomisawa, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081366&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9823429 103981394 CHEMBL540331 ZINC13801128 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771866 CCCN(C)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C17H22N2O/c1-3-8-19(2)14-6-4-12-5-7-16-17(15(12)9-14)13(11-20)10-18-16/h5,7,10-11,14,18H,3-4,6,8-9H2,1-2H3 LJZGVNXOVBOMKA-UHFFFAOYSA-N 50035350 8-(Methyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL71469 D(2) dopamine receptor Rattus norvegicus 151 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015980 103943376 CHEMBL71469 ZINC13741752 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771867 CCCN(CCc1ccccc1)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C23H28N2/c1-2-15-25(16-13-18-6-4-3-5-7-18)20-10-8-19-9-11-23-21(12-14-24-23)22(19)17-20/h3-7,9,11-12,14,20,24H,2,8,10,13,15-17H2,1H3 WUEDXQPULXUQHI-UHFFFAOYSA-N 50035351 CHEMBL72285::Phenethyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10449461 103943377 CHEMBL72285 ZINC13741740 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771877 CN(C)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C15H18N2O/c1-17(2)12-5-3-10-4-6-14-15(13(10)7-12)11(9-18)8-16-14/h4,6,8-9,12,16H,3,5,7H2,1-2H3/t12-/m1/s1 POFUCJDEJGFAAC-GFCCVEGCSA-N 50369019 CHEMBL1744040 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10060289 160848121 CHEMBL1744040 ZINC03798321 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771881 CN(C)[C@@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C14H18N2/c1-16(2)11-5-3-10-4-6-14-12(7-8-15-14)13(10)9-11/h4,6-8,11,15H,3,5,9H2,1-2H3/t11-/m1/s1 HENBLLXAHPTGHX-LLVKDONJSA-N 50044236 CHEMBL303339::Dimethyl-(R)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::R-(+)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044236&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14547414 103975559 CHEMBL303339 ZINC03798324 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771886 CCCN(CC1CC1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C20H26N2O/c1-2-9-22(12-14-3-4-14)17-7-5-15-6-8-19-20(18(15)10-17)16(13-23)11-21-19/h6,8,11,13-14,17,21H,2-5,7,9-10,12H2,1H3 LEMZVNAIJCRNJV-UHFFFAOYSA-N 50035353 8-(Cyclopropylmethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL71640 D(2) dopamine receptor Rattus norvegicus 228 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035353&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10267412 103943379 CHEMBL71640 ZINC12356091 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771889 CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)[C@@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C26H37N3O2/c1-4-13-28(14-5-6-15-29-24(30)17-26(2,3)18-25(29)31)20-9-7-19-8-10-23-21(11-12-27-23)22(19)16-20/h8,10-12,20,27H,4-7,9,13-18H2,1-3H3/t20-/m1/s1 GMWZSACWHHMURD-HXUWFJFHSA-N 50369020 CHEMBL1788200 D(2) dopamine receptor Rattus norvegicus 6.5 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11743043 160848122 CHEMBL1788200 ZINC13741747 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771890 C1Cc2ccc3[nH]ccc3c2CC1N1CCCCCC1 InChI=1S/C18H24N2/c1-2-4-12-20(11-3-1)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,1-5,7,11-13H2 GQADRQLOQQESDY-UHFFFAOYSA-N 50035357 8-Azepan-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]indole::CHEMBL73112 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035357&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11777831 103943383 CHEMBL73112 ZINC12355997 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771900 CCCN(CCCc1ccccc1OC)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C25H32N2O/c1-3-16-27(17-6-8-20-7-4-5-9-25(20)28-2)21-12-10-19-11-13-24-22(14-15-26-24)23(19)18-21/h4-5,7,9,11,13-15,21,26H,3,6,8,10,12,16-18H2,1-2H3 AAYJEWYLPYARLE-UHFFFAOYSA-N 50035358 CHEMBL306197::[3-(2-Methoxy-phenyl)-propyl]-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035358&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11740280 103943384 CHEMBL306197 ZINC13741744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771901 CCCN(CCC)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3 GKDJCOLVXBCNNK-UHFFFAOYSA-N 50035329 (+/-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine::CHEMBL65196::Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035329&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13096730 103943355 CHEMBL65196 ZINC03798326 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771905 CCCN(CCc1ccccc1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C24H28N2O/c1-2-13-26(14-12-18-6-4-3-5-7-18)21-10-8-19-9-11-23-24(22(19)15-21)20(17-27)16-25-23/h3-7,9,11,16-17,21,25H,2,8,10,12-15H2,1H3 GVFSLSBQCUQRBA-UHFFFAOYSA-N 50035336 8-(Phenethyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL304767 D(2) dopamine receptor Rattus norvegicus 62 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10021450 103943362 CHEMBL304767 ZINC13741759 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771907 CCCN(CCC)[C@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m0/s1 GKDJCOLVXBCNNK-HNNXBMFYSA-N 50035307 CHEMBL302171::Dipropyl-(S)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::S-(-)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035307&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10468376 103943333 CHEMBL302171 ZINC13738689 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771913 CCCN(CCC)CC1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C19H28N2/c1-3-11-21(12-4-2)14-15-5-6-16-7-8-19-17(9-10-20-19)18(16)13-15/h7-10,15,20H,3-6,11-14H2,1-2H3 KCNLBXIMJJIDHU-UHFFFAOYSA-N 50035346 CHEMBL70489::Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-ylmethyl)-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10085301 103943372 CHEMBL70489 ZINC13741777 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771922 CCCN(Cc1ccccc1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C23H26N2O/c1-2-12-25(15-17-6-4-3-5-7-17)20-10-8-18-9-11-22-23(21(18)13-20)19(16-26)14-24-22/h3-7,9,11,14,16,20,24H,2,8,10,12-13,15H2,1H3 UERVOFQYSXXVIG-UHFFFAOYSA-N 50035338 8-(Benzyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL420191 D(2) dopamine receptor Rattus norvegicus 90 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10383010 103943364 CHEMBL420191 ZINC13741757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771923 CCCN(CCC)[C@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m0/s1 DSEPKSLFXGYPIU-INIZCTEOSA-N 50035305 (S)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL307786 D(2) dopamine receptor Rattus norvegicus 423 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035305&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948210 103943331 CHEMBL307786 ZINC00005554 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779048 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779051 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 5.2 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779052 COc1cccc2C(CCCCN3CCN(CC3)c3ccccc3)CCCc12 InChI=1S/C25H34N2O/c1-28-25-15-8-13-23-21(10-7-14-24(23)25)9-5-6-16-26-17-19-27(20-18-26)22-11-3-2-4-12-22/h2-4,8,11-13,15,21H,5-7,9-10,14,16-20H2,1H3 BSTCJDNGLCVFKZ-UHFFFAOYSA-N 50054998 1-[4-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-4-phenyl-piperazine::CHEMBL341893 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054998&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10691080 103951572 CHEMBL341893 ZINC13760537 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779058 COc1cccc2C(CCCN3CCN(CC3)c3ccccc3)CCCc12 InChI=1S/C24H32N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h2-4,6,10-12,14,20H,5,7-9,13,15-19H2,1H3 JGCUFOXBUYJGBX-UHFFFAOYSA-N 50033857 1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL322275 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10361439 103942105 CHEMBL322275 ZINC13740694 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779064 COc1ccc2C(CCCN3CCN(CC3)c3ccccc3)CCCc2c1 InChI=1S/C24H32N2O/c1-27-23-12-13-24-20(7-5-8-21(24)19-23)9-6-14-25-15-17-26(18-16-25)22-10-3-2-4-11-22/h2-4,10-13,19-20H,5-9,14-18H2,1H3 IDTGHVXTQYWTPV-UHFFFAOYSA-N 50054997 1-[3-(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL147678 D(2) dopamine receptor Rattus norvegicus 91 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054997&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473986 103951571 CHEMBL147678 ZINC13760532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779065 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779067 COc1ccc2CCC=C(CCCN3CCN(CC3)c3ccccc3)c2c1 InChI=1S/C24H30N2O/c1-27-23-13-12-21-8-5-7-20(24(21)19-23)9-6-14-25-15-17-26(18-16-25)22-10-3-2-4-11-22/h2-4,7,10-13,19H,5-6,8-9,14-18H2,1H3 GFPSKAXAVWQUOE-UHFFFAOYSA-N 50033845 1-[3-(7-Methoxy-3,4-dihydro-naphthalen-1-yl)-propyl]-4-phenyl-piperazine::CHEMBL143110 D(2) dopamine receptor Rattus norvegicus 157 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406366 103942093 CHEMBL143110 ZINC13733291 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779069 COc1ccc2CCC(CCN3CCN(CC3)c3ccccc3)=Cc2c1 InChI=1S/C23H28N2O/c1-26-23-10-9-20-8-7-19(17-21(20)18-23)11-12-24-13-15-25(16-14-24)22-5-3-2-4-6-22/h2-6,9-10,17-18H,7-8,11-16H2,1H3 HMRKDGYERNRWGG-UHFFFAOYSA-N 50054989 1-[2-(7-Methoxy-3,4-dihydro-naphthalen-2-yl)-ethyl]-4-phenyl-piperazine::CHEMBL342518 D(2) dopamine receptor Rattus norvegicus 136 ChEMBL 10.1021/jm9604538 10.7270/Q2ZG6SX1 8960552 Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fornaretto, MG; Caccia, C; McArthur, RA Universit£ di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054989&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10665424 103951563 CHEMBL342518 ZINC13760540 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771933 CN(C)[C@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C15H18N2O/c1-17(2)12-5-3-10-4-6-14-15(13(10)7-12)11(9-18)8-16-14/h4,6,8-9,12,16H,3,5,7H2,1-2H3/t12-/m0/s1 POFUCJDEJGFAAC-LBPRGKRZSA-N 50369021 CHEMBL1788196 D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369021&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10331989 160848123 CHEMBL1788196 ZINC04637976 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771940 CCCN(CCCc1ccccc1)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C25H30N2O/c1-2-14-27(15-6-9-19-7-4-3-5-8-19)22-12-10-20-11-13-24-25(23(20)16-22)21(18-28)17-26-24/h3-5,7-8,11,13,17-18,22,26H,2,6,9-10,12,14-16H2,1H3/t22-/m1/s1 YXESVSAQXNVTIV-JOCHJYFZSA-N 50369022 CHEMBL1788197 D(2) dopamine receptor Rattus norvegicus 5.8 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369022&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11740144 160848124 CHEMBL1788197 ZINC13741768 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771942 C1CCN(C1)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C16H20N2/c1-2-10-18(9-1)13-5-3-12-4-6-16-14(7-8-17-16)15(12)11-13/h4,6-8,13,17H,1-3,5,9-11H2 ZHYVAHQXIANQII-UHFFFAOYSA-N 50035365 8-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]indole::CHEMBL69560 D(2) dopamine receptor Rattus norvegicus 94 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035365 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035365&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10354282 103943391 CHEMBL69560 ZINC12355955 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771944 CCCNC1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C16H20N2O/c1-2-7-17-13-5-3-11-4-6-15-16(14(11)8-13)12(10-19)9-18-15/h4,6,9-10,13,17-18H,2-3,5,7-8H2,1H3 HUISJGMFDCMBAG-UHFFFAOYSA-N 50035356 8-Propylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL312525 D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10400189 103943382 CHEMBL312525 ZINC13741750 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771947 CCCN(CC=C)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H24N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h3,6,8-10,15,19H,1,4-5,7,11-13H2,2H3 IDHCAJSSWVNHQO-UHFFFAOYSA-N 50035362 Allyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine::CHEMBL309121 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035362 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035362&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378357 103943388 CHEMBL309121 ZINC13741733 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771953 CCCNC1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C15H20N2/c1-2-8-16-12-5-3-11-4-6-15-13(7-9-17-15)14(11)10-12/h4,6-7,9,12,16-17H,2-3,5,8,10H2,1H3 HFQNQSPPIPXJLL-UHFFFAOYSA-N 50035348 CHEMBL305976::Propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10376496 103943374 CHEMBL305976 ZINC13741729 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771958 CCCN(CCCc1ccccc1OC)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C26H32N2O2/c1-3-14-28(15-6-8-20-7-4-5-9-25(20)30-2)22-12-10-19-11-13-24-26(23(19)16-22)21(18-29)17-27-24/h4-5,7,9,11,13,17-18,22,27H,3,6,8,10,12,14-16H2,1-2H3 HXXAWZFROYWOFG-UHFFFAOYSA-N 50035360 8-{[3-(2-Methoxy-phenyl)-propyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL305837 D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035360&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10069802 103943386 CHEMBL305837 ZINC13741763 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771959 CN(C)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C14H18N2/c1-16(2)11-5-3-10-4-6-14-12(7-8-15-14)13(10)9-11/h4,6-8,11,15H,3,5,9H2,1-2H3 HENBLLXAHPTGHX-UHFFFAOYSA-N 50017520 (+/-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine::CHEMBL413105::Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129503 103928788 CHEMBL413105 ZINC05965209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771963 CN(C)[C@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C14H18N2/c1-16(2)11-5-3-10-4-6-14-12(7-8-15-14)13(10)9-11/h4,6-8,11,15H,3,5,9H2,1-2H3/t11-/m0/s1 HENBLLXAHPTGHX-NSHDSACASA-N 50044235 CHEMBL292274::Dimethyl-(S)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::S-(-)-Dimethyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 377 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50044235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50044235&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14547415 103975558 CHEMBL292274 ZINC05965209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771964 CCCN(CCC)[C@@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C18H26N2/c1-3-11-20(12-4-2)15-7-5-14-6-8-18-16(9-10-19-18)17(14)13-15/h6,8-10,15,19H,3-5,7,11-13H2,1-2H3/t15-/m1/s1 GKDJCOLVXBCNNK-OAHLLOKOSA-N 50035330 CHEMBL302172::Dipropyl-(R)-6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl-amine::R-(+)-Dipropyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 7.4 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10858566 103943356 CHEMBL302172 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771966 C(CNCC1CCc2ccc3[nH]ccc3c2C1)Cc1ccccc1 InChI=1S/C22H26N2/c1-2-5-17(6-3-1)7-4-13-23-16-18-8-9-19-10-11-22-20(12-14-24-22)21(19)15-18/h1-3,5-6,10-12,14,18,23-24H,4,7-9,13,15-16H2 ZBSUSNSHVMDYGJ-UHFFFAOYSA-N 50035361 (3-Phenyl-propyl)-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-ylmethyl)-amine::CHEMBL70980 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035361 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035361&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10245352 103943387 CHEMBL70980 ZINC13741775 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771968 CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C27H37N3O3/c1-4-11-29(12-5-6-13-30-24(32)15-27(2,3)16-25(30)33)21-9-7-19-8-10-23-26(22(19)14-21)20(18-31)17-28-23/h8,10,17-18,21,28H,4-7,9,11-16H2,1-3H3 NLXASJVETPACMT-UHFFFAOYSA-N 50035337 8-{[4-(4,4-Dimethyl-2,6-dioxo-piperidin-1-yl)-butyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL423127 D(2) dopamine receptor Rattus norvegicus 136 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9981270 103943363 CHEMBL423127 ZINC13741767 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771971 CCCN(CCC)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3/t16-/m1/s1 DSEPKSLFXGYPIU-MRXNPFEDSA-N 50035303 (R)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL71625 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035303&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10870264 103943329 CHEMBL71625 ZINC03782839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771982 CCCN(CC(C)C)[C@@H]1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C19H28N2/c1-4-11-21(13-14(2)3)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,4-5,7,11-13H2,1-3H3/t16-/m1/s1 MWJQJAAIZHSGLU-MRXNPFEDSA-N 50369018 CHEMBL1744041 D(2) dopamine receptor Rattus norvegicus 5.7 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369018&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11778645 160848120 CHEMBL1744041 ZINC13741734 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771990 O=Cc1c[nH]c2ccc3CCC(Cc3c12)N1CCCCCC1 InChI=1S/C19H24N2O/c22-13-15-12-20-18-8-6-14-5-7-16(11-17(14)19(15)18)21-9-3-1-2-4-10-21/h6,8,12-13,16,20H,1-5,7,9-11H2 DDSJSYAJAKFVHY-UHFFFAOYSA-N 50035366 8-Azepan-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL306198 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035366 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035366&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10108623 103943392 CHEMBL306198 ZINC13741773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771992 CCCN(CCc1cccs1)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C21H26N2S/c1-2-12-23(13-10-18-4-3-14-24-18)17-7-5-16-6-8-21-19(9-11-22-21)20(16)15-17/h3-4,6,8-9,11,14,17,22H,2,5,7,10,12-13,15H2,1H3 OLGRDJBZDHQHOJ-UHFFFAOYSA-N 50035345 CHEMBL71145::Propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-(2-thiophen-2-yl-ethyl)-amine D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10382523 103943371 CHEMBL71145 ZINC13741742 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50772009 CCCN(CCc1cccs1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C22H26N2OS/c1-2-10-24(11-9-19-4-3-12-26-19)18-7-5-16-6-8-21-22(20(16)13-18)17(15-25)14-23-21/h3-4,6,8,12,14-15,18,23H,2,5,7,9-11,13H2,1H3 NATZFOMSDOBVCC-UHFFFAOYSA-N 50035363 8-[Propyl-(2-thiophen-2-yl-ethyl)-amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL72062 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035363 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035363&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406614 103943389 CHEMBL72062 ZINC13741761 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50772014 CCCN(Cc1ccccc1)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C22H26N2/c1-2-14-24(16-17-6-4-3-5-7-17)19-10-8-18-9-11-22-20(12-13-23-22)21(18)15-19/h3-7,9,11-13,19,23H,2,8,10,14-16H2,1H3 UQIBBMPERXPJEF-UHFFFAOYSA-N 50035341 Benzyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine::CHEMBL70606 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10064500 103943367 CHEMBL70606 ZINC13741738 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50772023 CCCN(CCC)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3 DSEPKSLFXGYPIU-UHFFFAOYSA-N 50035320 (+/-)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL304426 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 178081 103943346 CHEMBL304426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50772027 CCCN(CC=C)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H24N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h3,6,8,12-13,16,20H,1,4-5,7,9-11H2,2H3 DBGOPRYLVZPMHQ-UHFFFAOYSA-N 50035347 8-(Allyl-propyl-amino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL304984 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10379833 103943373 CHEMBL304984 ZINC13741754 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50772029 CCCN(CCCc1ccccc1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C25H30N2O/c1-2-14-27(15-6-9-19-7-4-3-5-8-19)22-12-10-20-11-13-24-25(23(20)16-22)21(18-28)17-26-24/h3-5,7-8,11,13,17-18,22,26H,2,6,9-10,12,14-16H2,1H3 YXESVSAQXNVTIV-UHFFFAOYSA-N 50035359 8-[(3-Phenyl-propyl)-propyl-amino]-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL70680 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035359 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035359&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10044965 103943385 CHEMBL70680 ZINC13741769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50772031 CCCN(CC(C)C)[C@@H]1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C20H28N2O/c1-4-9-22(12-14(2)3)17-7-5-15-6-8-19-20(18(15)10-17)16(13-23)11-21-19/h6,8,11,13-14,17,21H,4-5,7,9-10,12H2,1-3H3/t17-/m1/s1 WQCPRDLCQLSJEB-QGZVFWFLSA-N 50369017 CHEMBL1744039 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369017&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10358173 160848119 CHEMBL1744039 ZINC13741755 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50772032 CCCN(CC1CC1)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C19H26N2/c1-2-11-21(13-14-3-4-14)16-7-5-15-6-8-19-17(9-10-20-19)18(15)12-16/h6,8-10,14,16,20H,2-5,7,11-13H2,1H3 JBAXPLUIYUXVCS-UHFFFAOYSA-N 50035355 CHEMBL69729::Cyclopropylmethyl-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10265814 103943381 CHEMBL69729 ZINC13741736 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50772033 CCCN(CCCOc1cccc(Cl)c1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C25H29ClN2O2/c1-2-11-28(12-4-13-30-22-6-3-5-20(26)14-22)21-9-7-18-8-10-24-25(23(18)15-21)19(17-29)16-27-24/h3,5-6,8,10,14,16-17,21,27H,2,4,7,9,11-13,15H2,1H3 KTENZVQFGHICMF-UHFFFAOYSA-N 50035343 8-{[3-(3-Chloro-phenoxy)-propyl]-propyl-amino}-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL303921 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10432512 103943369 CHEMBL303921 ZINC13741765 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50772034 O=Cc1c[nH]c2ccc3CCC(Cc3c12)N1CCCC1 InChI=1S/C17H20N2O/c20-11-13-10-18-16-6-4-12-3-5-14(9-15(12)17(13)16)19-7-1-2-8-19/h4,6,10-11,14,18H,1-3,5,7-9H2 JPRFHSQJEMXCKR-UHFFFAOYSA-N 50035342 8-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL308934 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10445755 103943368 CHEMBL308934 ZINC13741771 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50772035 CCCN(CCCOc1cccc(Cl)c1)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C24H29ClN2O/c1-2-13-27(14-4-15-28-21-6-3-5-19(25)16-21)20-9-7-18-8-10-24-22(11-12-26-24)23(18)17-20/h3,5-6,8,10-12,16,20,26H,2,4,7,9,13-15,17H2,1H3 INAFJGHXLCGHAU-UHFFFAOYSA-N 50035344 CHEMBL420748::[3-(3-Chloro-phenoxy)-propyl]-propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amine D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10475893 103943370 CHEMBL420748 ZINC13741746 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50771996 CCCN(CCCCN1C(=O)CC(C)(C)CC1=O)C1CCc2ccc3[nH]ccc3c2C1 InChI=1S/C26H37N3O2/c1-4-13-28(14-5-6-15-29-24(30)17-26(2,3)18-25(29)31)20-9-7-19-8-10-23-21(11-12-27-23)22(19)16-20/h8,10-12,20,27H,4-7,9,13-18H2,1-3H3 GMWZSACWHHMURD-UHFFFAOYSA-N 50035352 4,4-Dimethyl-1-{4-[propyl-(6,7,8,9-tetrahydro-3H-benzo[e]indol-8-yl)-amino]-butyl}-piperidine-2,6-dione::CHEMBL69943 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm00012a022 10.7270/Q28G8MBW 7783153 Ennis, MD; Stjernlof, P; Hoffman, RL; Ghazal, NB; Smith, MW; Svensson, K; Wikstrom, H; Haadsma-Svensson, SR; Lin, CH Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11743042 103943378 CHEMBL69943 ZINC13741748 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774115 COc1ccccc1N1CCN(Cc2ccc(CN3CCCCCCC3=O)o2)CC1 InChI=1S/C24H33N3O3/c1-29-23-9-6-5-8-22(23)26-16-14-25(15-17-26)18-20-11-12-21(30-20)19-27-13-7-3-2-4-10-24(27)28/h5-6,8-9,11-12H,2-4,7,10,13-19H2,1H3 FARTWIHPHUYFOY-UHFFFAOYSA-N 50029244 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-furan-2-ylmethyl}-azocan-2-one;succinate D(2) dopamine receptor Rattus norvegicus 1431 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029244&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10093057 103938315 ZINC12356342 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774119 CNC(=O)c1ccc(CN2CCN(CC2)c2ccccc2OC)n1C InChI=1S/C19H26N4O2/c1-20-19(24)17-9-8-15(21(17)2)14-22-10-12-23(13-11-22)16-6-4-5-7-18(16)25-3/h4-9H,10-14H2,1-3H3,(H,20,24) BSWBSETXCRFNTL-UHFFFAOYSA-N 50029248 5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrole-2-carboxylic acid methylamide;succinate D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029248&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593420 103938319 ZINC13743845 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774120 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774122 CC(C)Oc1ccccc1N1CCN(Cc2cc(cs2)C(=O)N2CCCCC2)CC1 InChI=1S/C24H33N3O2S/c1-19(2)29-23-9-5-4-8-22(23)26-14-12-25(13-15-26)17-21-16-20(18-30-21)24(28)27-10-6-3-7-11-27/h4-5,8-9,16,18-19H,3,6-7,10-15,17H2,1-2H3 IDMGFFRFALKXDG-UHFFFAOYSA-N 50029249 CHEMBL542483::{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-thiophen-3-yl}-piperidin-1-yl-methanone; hydrochloride D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10693782 103938320 CHEMBL542483 ZINC53045773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774123 CC(C)NC(=O)c1ccc(CN2CCN(CC2)c2ccccc2OC(C)C)n1C InChI=1S/C23H34N4O2/c1-17(2)24-23(28)21-11-10-19(25(21)5)16-26-12-14-27(15-13-26)20-8-6-7-9-22(20)29-18(3)4/h6-11,17-18H,12-16H2,1-5H3,(H,24,28) QFCUDNIUXNPYTD-UHFFFAOYSA-N 50029252 5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrole-2-carboxylic acid isopropylamide;succinate D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029252&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10810907 103938323 ZINC12356293 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774124 CC(C)Oc1ccccc1N1CCN(Cc2ccc(s2)C(=O)N2CCCCC2)CC1 InChI=1S/C24H33N3O2S/c1-19(2)29-22-9-5-4-8-21(22)26-16-14-25(15-17-26)18-20-10-11-23(30-20)24(28)27-12-6-3-7-13-27/h4-5,8-11,19H,3,6-7,12-18H2,1-2H3 PZTCPGDPJLEQHE-UHFFFAOYSA-N 50029250 {5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-thiophen-2-yl}-piperidin-1-yl-methanone;succinate D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9888780 103938321 ZINC53243588 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774125 CC(C)Oc1ccccc1N1CCN(Cc2ccc(C(=O)N3CCCCC3)n2C)CC1 InChI=1S/C25H36N4O2/c1-20(2)31-24-10-6-5-9-22(24)28-17-15-27(16-18-28)19-21-11-12-23(26(21)3)25(30)29-13-7-4-8-14-29/h5-6,9-12,20H,4,7-8,13-19H2,1-3H3 SZIOKOQNKGACDV-UHFFFAOYSA-N 50029251 CHEMBL543905::{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-yl}-piperidin-1-yl-methanone; hydrochloride D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10836100 103938322 CHEMBL543905 ZINC13743863 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774130 CC(C)Oc1ccccc1N1CCN(Cc2cccc(c2)C(=O)N2CCCCC2)CC1 InChI=1S/C26H35N3O2/c1-21(2)31-25-12-5-4-11-24(25)28-17-15-27(16-18-28)20-22-9-8-10-23(19-22)26(30)29-13-6-3-7-14-29/h4-5,8-12,19,21H,3,6-7,13-18,20H2,1-2H3 ZKZFPRUSWCYSGT-UHFFFAOYSA-N 50029257 (3-((4-(2-isopropoxyphenyl)piperazin-1-yl)methyl)phenyl)(piperidin-1-yl)methanone::CHEMBL10085::RWJ-377796::mazapertine::{3-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-phenyl}-piperidin-1-yl-methanone D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029257&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60820 103938328 CHEMBL10085 ZINC52956332 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774134 CCCN(Cc1ccc(CN2CCN(CC2)c2ccccc2OC)n1C)S(=O)(=O)c1ccccc1 InChI=1S/C27H36N4O3S/c1-4-16-31(35(32,33)25-10-6-5-7-11-25)22-24-15-14-23(28(24)2)21-29-17-19-30(20-18-29)26-12-8-9-13-27(26)34-3/h5-15H,4,16-22H2,1-3H3 GCTPTAYMTYWDAX-UHFFFAOYSA-N 50029259 CHEMBL133550::N-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-N-propyl-benzenesulfonamide D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029259&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10577218 103938330 CHEMBL133550 ZINC13743861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774135 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C25H36N4O2/c1-20(2)31-24-9-5-4-8-23(24)28-16-14-27(15-17-28)18-21-11-12-22(26(21)3)19-29-13-7-6-10-25(29)30/h4-5,8-9,11-12,20H,6-7,10,13-19H2,1-3H3 BLFPEKXTSDYQOQ-UHFFFAOYSA-N 50001869 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-piperidin-2-one::CHEMBL428175::RWJ-25730 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9910257 103916236 CHEMBL428175 ZINC53255684 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774136 CC(C)Oc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCCCCC3)n2C)CC1 InChI=1S/C28H40N4O3/c1-22(2)35-26-11-7-6-10-24(26)31-20-18-30(19-21-31)17-14-23-12-13-25(29(23)3)27(33)28(34)32-15-8-4-5-9-16-32/h6-7,10-13,22H,4-5,8-9,14-21H2,1-3H3 GDEVLSFEESNUML-UHFFFAOYSA-N 50029255 1-Azepan-1-yl-2-(5-{2-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-ethyl}-1-methyl-1H-pyrrol-2-yl)-ethane-1,2-dione;succinate D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11798931 103938326 ZINC13743826 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774137 CC(C)Oc1ccccc1N1CCN(Cc2ccc(s2)C(=O)N2CCCCCC2)CC1 InChI=1S/C25H35N3O2S/c1-20(2)30-23-10-6-5-9-22(23)27-17-15-26(16-18-27)19-21-11-12-24(31-21)25(29)28-13-7-3-4-8-14-28/h5-6,9-12,20H,3-4,7-8,13-19H2,1-2H3 HVVWMUYWFADJPJ-UHFFFAOYSA-N 50029260 Azepan-1-yl-{5-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-thiophen-2-yl}-methanone; hydrochloride::CHEMBL538280 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029260&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599297 103938331 CHEMBL538280 ZINC53022870 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774141 CC(C)Oc1ccccc1N1CCN(Cc2cccc(CN3CCCCC3=O)n2)CC1 InChI=1S/C25H34N4O2/c1-20(2)31-24-11-4-3-10-23(24)28-16-14-27(15-17-28)18-21-8-7-9-22(26-21)19-29-13-6-5-12-25(29)30/h3-4,7-11,20H,5-6,12-19H2,1-2H3 PLVXGHMFJNEQRI-UHFFFAOYSA-N 50029265 1-{6-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-pyridin-2-ylmethyl}-piperidin-2-one; hydrochloride::CHEMBL553555 D(2) dopamine receptor Rattus norvegicus 2415 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029265&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740929 103938336 CHEMBL553555 ZINC52541494 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774144 COc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)C(C)=O)n2C)CC1 InChI=1S/C23H34N4O2/c1-18(2)27(19(3)28)17-21-11-10-20(24(21)4)16-25-12-14-26(15-13-25)22-8-6-7-9-23(22)29-5/h6-11,18H,12-17H2,1-5H3 LKZRCPKUNMYEDG-UHFFFAOYSA-N 50029263 N-Isopropyl-N-{5-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-acetamide;succinate D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029263&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10572961 103938334 ZINC13743838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785134 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCN(C)C InChI=1S/C18H28N2O/c1-13-17-11-14-5-6-15(21)12-16(14)18(13,2)7-8-20(17)10-9-19(3)4/h5-6,12-13,17,21H,7-11H2,1-4H3/t13-,17+,18-/m1/s1 RGGGRGFCVIHGAI-JEBQAFNWSA-N 50064189 (2S,6R,11S)-3-(2-Dimethylamino-ethyl)-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL37966 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970333f 10.7270/Q2C24X3R 9572883 Ronsisvalle, G; Marrazzo, A; Prezzavento, O; Pasquinucci, L; Vittorio, F; Pittala, V; Pappalardo, MS; Cacciaguerra, S; Spampinato, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064189 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064189&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10517496 103959255 CHEMBL37966 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785151 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCN1CCCCCC1 InChI=1S/C22H34N2O/c1-17-21-15-18-7-8-19(25)16-20(18)22(17,2)9-12-24(21)14-13-23-10-5-3-4-6-11-23/h7-8,16-17,21,25H,3-6,9-15H2,1-2H3/t17-,21+,22-/m1/s1 KHQLKMURGRQDRK-VOQZNFBZSA-N 50064187 (2S,6R,11S)-3-(2-Azepan-1-yl-ethyl)-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL290675 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970333f 10.7270/Q2C24X3R 9572883 Ronsisvalle, G; Marrazzo, A; Prezzavento, O; Pasquinucci, L; Vittorio, F; Pittala, V; Pappalardo, MS; Cacciaguerra, S; Spampinato, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064187 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064187&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10807270 103959253 CHEMBL290675 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785160 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1021/jm970333f 10.7270/Q2C24X3R 9572883 Ronsisvalle, G; Marrazzo, A; Prezzavento, O; Pasquinucci, L; Vittorio, F; Pittala, V; Pappalardo, MS; Cacciaguerra, S; Spampinato, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785163 CC1C2Cc3ccc(O)cc3C1CCN2CC=C InChI=1S/C16H21NO/c1-3-7-17-8-6-14-11(2)16(17)9-12-4-5-13(18)10-15(12)14/h3-5,10-11,14,16,18H,1,6-9H2,2H3 ZOJJMIHMCCDEFD-UHFFFAOYSA-N 50368882 CHEMBL147585::SK&F-10047::SK-10047 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970333f 10.7270/Q2C24X3R 9572883 Ronsisvalle, G; Marrazzo, A; Prezzavento, O; Pasquinucci, L; Vittorio, F; Pittala, V; Pappalardo, MS; Cacciaguerra, S; Spampinato, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368882&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44364124 160847984 CHEMBL147585 ZINC27555679 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785164 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCN1CCCCC1 InChI=1S/C21H32N2O/c1-16-20-14-17-6-7-18(24)15-19(17)21(16,2)8-11-23(20)13-12-22-9-4-3-5-10-22/h6-7,15-16,20,24H,3-5,8-14H2,1-2H3/t16-,20+,21-/m1/s1 PCYNRFPIZWFFRC-TYCQWZJGSA-N 50064193 (2S,6R,11S)-6,11-Dimethyl-3-(2-piperidin-1-yl-ethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL41313 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970333f 10.7270/Q2C24X3R 9572883 Ronsisvalle, G; Marrazzo, A; Prezzavento, O; Pasquinucci, L; Vittorio, F; Pittala, V; Pappalardo, MS; Cacciaguerra, S; Spampinato, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064193 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064193&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10336644 103959259 CHEMBL41313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50785171 C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CCN1CCCC1 InChI=1S/C20H30N2O/c1-15-19-13-16-5-6-17(23)14-18(16)20(15,2)7-10-22(19)12-11-21-8-3-4-9-21/h5-6,14-15,19,23H,3-4,7-13H2,1-2H3/t15-,19+,20-/m1/s1 KBVYTXIGZVJMDH-UIAACRFSSA-N 50064191 (2S,6R,11S)-6,11-Dimethyl-3-(2-pyrrolidin-1-yl-ethyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL43398 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm970333f 10.7270/Q2C24X3R 9572883 Ronsisvalle, G; Marrazzo, A; Prezzavento, O; Pasquinucci, L; Vittorio, F; Pittala, V; Pappalardo, MS; Cacciaguerra, S; Spampinato, S University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064191&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10852782 103959257 CHEMBL43398 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50786966 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 240 ChEMBL 10.1021/jm9706832 10.7270/Q2JH3MVJ 9748351 Campiani, G; Nacci, V; Bechelli, S; Ciani, SM; Garofalo, A; Fiorini, I; Wikstrom, H; de Boer, P; Liao, Y; Tepper, PG; Cagnotto, A; Mennini, T Universita' di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50786967 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/jm9706832 10.7270/Q2JH3MVJ 9748351 Campiani, G; Nacci, V; Bechelli, S; Ciani, SM; Garofalo, A; Fiorini, I; Wikstrom, H; de Boer, P; Liao, Y; Tepper, PG; Cagnotto, A; Mennini, T Universita' di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50786972 CN1CCN(CC1)C1Cn2cccc2Sc2ccc(Cl)cc12 InChI=1S/C17H20ClN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11,15H,7-10,12H2,1H3 YQXNPUPTPJOJOV-UHFFFAOYSA-N 50066910 (+/-)7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(R)-(-)7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(S)-(+)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene(ST1460)::7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL120512 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1021/jm9706832 10.7270/Q2JH3MVJ 9748351 Campiani, G; Nacci, V; Bechelli, S; Ciani, SM; Garofalo, A; Fiorini, I; Wikstrom, H; de Boer, P; Liao, Y; Tepper, PG; Cagnotto, A; Mennini, T Universita' di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066910&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9884087 103961446 CHEMBL120512 ZINC22925209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50786982 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm9706832 10.7270/Q2JH3MVJ 9748351 Campiani, G; Nacci, V; Bechelli, S; Ciani, SM; Garofalo, A; Fiorini, I; Wikstrom, H; de Boer, P; Liao, Y; Tepper, PG; Cagnotto, A; Mennini, T Universita' di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50786985 CN1CCN(CC1)C1Cn2cccc2Sc2ccccc12 InChI=1S/C17H21N3S/c1-18-9-11-19(12-10-18)15-13-20-8-4-7-17(20)21-16-6-3-2-5-14(15)16/h2-8,15H,9-13H2,1H3 PUSGNVOFKAPWQM-UHFFFAOYSA-N 50066912 (+/-)9-(4-Methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(R)-(-)9-(4-Methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(S)-(+)9-(4-Methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene(ST1622)::9-(4-Methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL333246 D(2) dopamine receptor Rattus norvegicus 70 ChEMBL 10.1021/jm9706832 10.7270/Q2JH3MVJ 9748351 Campiani, G; Nacci, V; Bechelli, S; Ciani, SM; Garofalo, A; Fiorini, I; Wikstrom, H; de Boer, P; Liao, Y; Tepper, PG; Cagnotto, A; Mennini, T Universita' di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066912&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817779 103961448 CHEMBL333246 ZINC22778669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50768467 Ic1ccc(cc1)C1(CCCC1)C(=O)OCCN1CCC(CC1)c1ccccc1 InChI=1S/C25H30INO2/c26-23-10-8-22(9-11-23)25(14-4-5-15-25)24(28)29-19-18-27-16-12-21(13-17-27)20-6-2-1-3-7-20/h1-3,6-11,21H,4-5,12-19H2 HHWKRRPTCYPMFB-UHFFFAOYSA-N 50038709 1-(4-Iodo-phenyl)-cyclopentanecarboxylic acid 2-(4-phenyl-piperidin-1-yl)-ethyl ester; hydrochloride::CHEMBL554628 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm00039a008 10.7270/Q2QZ2BMR 8027978 Hudkins, RL; Mailman, RB; DeHaven-Hudkins, DL Albany Molecular Research, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038709&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10074800 103945983 CHEMBL554628 ZINC13737399 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50770359 O=C(N[C@H]1CC[C@H]2C[C@@H](CC[C@@H]2C1)N1CCN(CC1)c1ccccn1)c1ccccc1 InChI=1S/C26H34N4O/c31-26(20-6-2-1-3-7-20)28-23-11-9-22-19-24(12-10-21(22)18-23)29-14-16-30(17-15-29)25-8-4-5-13-27-25/h1-8,13,21-24H,9-12,14-19H2,(H,28,31)/t21-,22+,23+,24-/m1/s1 OVQXIVRARLGKOO-NAVOZUGXSA-N 50038283 CHEMBL337848::N-[(2S,4aS,6R,8aR)-6-(4-Pyridin-2-yl-piperazin-1-yl)-decahydro-naphthalen-2-yl]-benzamide D(2) dopamine receptor Rattus norvegicus 7100 ChEMBL 10.1021/jm00050a022 10.7270/Q2SN09KN 7990124 Wustrow, DJ; Wise, LD; Cody, DM; MacKenzie, RG; Georgic, LM; Pugsley, TA; Heffner, TG Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10047649 103945720 CHEMBL337848 ZINC13739891 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50770360 O=C(N[C@@H]1CC[C@H]2C[C@@H](CC[C@@H]2C1)N1CCN(CC1)c1ccccn1)c1ccccc1 InChI=1S/C26H34N4O/c31-26(20-6-2-1-3-7-20)28-23-11-9-22-19-24(12-10-21(22)18-23)29-14-16-30(17-15-29)25-8-4-5-13-27-25/h1-8,13,21-24H,9-12,14-19H2,(H,28,31)/t21-,22+,23-,24-/m1/s1 OVQXIVRARLGKOO-UEQSERJNSA-N 50038282 CHEMBL133093::N-[(2R,4aS,6R,8aR)-6-(4-Pyridin-2-yl-piperazin-1-yl)-decahydro-naphthalen-2-yl]-benzamide D(2) dopamine receptor Rattus norvegicus 5800 ChEMBL 10.1021/jm00050a022 10.7270/Q2SN09KN 7990124 Wustrow, DJ; Wise, LD; Cody, DM; MacKenzie, RG; Georgic, LM; Pugsley, TA; Heffner, TG Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025040 103945719 CHEMBL133093 ZINC13739892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50770364 O=C(N[C@@H]1CC[C@H]2C[C@H](CC[C@@H]2C1)N1CCN(CC1)c1ccccn1)c1ccccc1 InChI=1S/C26H34N4O/c31-26(20-6-2-1-3-7-20)28-23-11-9-22-19-24(12-10-21(22)18-23)29-14-16-30(17-15-29)25-8-4-5-13-27-25/h1-8,13,21-24H,9-12,14-19H2,(H,28,31)/t21-,22+,23-,24+/m1/s1 OVQXIVRARLGKOO-QPXUXIHVSA-N 50038284 CHEMBL335403::N-[(2R,4aS,6S,8aR)-6-(4-Pyridin-2-yl-piperazin-1-yl)-decahydro-naphthalen-2-yl]-benzamide D(2) dopamine receptor Rattus norvegicus 73 ChEMBL 10.1021/jm00050a022 10.7270/Q2SN09KN 7990124 Wustrow, DJ; Wise, LD; Cody, DM; MacKenzie, RG; Georgic, LM; Pugsley, TA; Heffner, TG Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038284&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10047648 103945721 CHEMBL335403 ZINC18178875 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50770367 O=C(N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccn2)CC1)c1ccccc1 InChI=1S/C24H32N4O/c29-24(21-6-2-1-3-7-21)26-22-11-9-20(10-12-22)13-15-27-16-18-28(19-17-27)23-8-4-5-14-25-23/h1-8,14,20,22H,9-13,15-19H2,(H,26,29)/t20-,22- MNTHFSDLZXHALL-AQYVVDRMSA-N 50038287 CHEMBL135387::N-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyclohexyl}-benzamide D(2) dopamine receptor Rattus norvegicus 443 ChEMBL 10.1021/jm00050a022 10.7270/Q2SN09KN 7990124 Wustrow, DJ; Wise, LD; Cody, DM; MacKenzie, RG; Georgic, LM; Pugsley, TA; Heffner, TG Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50038287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50038287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15045457 103945724 CHEMBL135387 ZINC12356300 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774147 CCCCS(=O)(=O)N(C)Cc1ccc(CN2CCN(CC2)c2ccccc2OC(C)C)n1C InChI=1S/C25H40N4O3S/c1-6-7-18-33(30,31)26(4)19-22-12-13-23(27(22)5)20-28-14-16-29(17-15-28)24-10-8-9-11-25(24)32-21(2)3/h8-13,21H,6-7,14-20H2,1-5H3 YPFMMMZKYKDYMO-UHFFFAOYSA-N 50029254 Butane-1-sulfonic acid {5-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-methyl-amide;succinate D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10838328 103938325 ZINC13743841 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774150 O=C1CCCCN1Cc1ccc(CN2CCN(CC2)c2cccc3ccoc23)s1 InChI=1S/C23H27N3O2S/c27-22-6-1-2-10-26(22)17-20-8-7-19(29-20)16-24-11-13-25(14-12-24)21-5-3-4-18-9-15-28-23(18)21/h3-5,7-9,15H,1-2,6,10-14,16-17H2 HFSBIPAYKIUXKW-UHFFFAOYSA-N 50029246 1-[5-(4-Benzofuran-7-yl-piperazin-1-ylmethyl)-thiophen-2-ylmethyl]-piperidin-2-one;succinate D(2) dopamine receptor Rattus norvegicus 333 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029246&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740276 103938317 ZINC53246842 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774153 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 367 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774155 COc1ccccc1N1CCN(Cc2ccc(CN(Cc3ccccc3)C(=O)c3ccccc3)n2C)CC1 InChI=1S/C32H36N4O2/c1-33-28(24-34-19-21-35(22-20-34)30-15-9-10-16-31(30)38-2)17-18-29(33)25-36(23-26-11-5-3-6-12-26)32(37)27-13-7-4-8-14-27/h3-18H,19-25H2,1-2H3 GMRLQCUMWHHPJZ-UHFFFAOYSA-N 50029274 N-Benzyl-N-{5-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-benzamide;succinate D(2) dopamine receptor Rattus norvegicus >30 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029274&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10673242 103938345 ZINC13743859 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774156 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.20 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774157 CC(C)Oc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCOCC3)n2C)CC1 InChI=1S/C26H36N4O4/c1-20(2)34-24-7-5-4-6-22(24)29-14-12-28(13-15-29)11-10-21-8-9-23(27(21)3)25(31)26(32)30-16-18-33-19-17-30/h4-9,20H,10-19H2,1-3H3 AXDHLIUKVGWRAC-UHFFFAOYSA-N 50029258 3.303211-(5-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-ethyl}-1-methyl-1H-pyrrol-2-yl)-2-morpholin-4-yl-ethane-1,2-dione;succinate D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029258&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10671988 103938329 ZINC13743827 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774158 COc1ccccc1N1CCN(Cc2ccc(CN(C)C(C)=O)n2C)CC1 InChI=1S/C21H30N4O2/c1-17(26)22(2)15-18-9-10-19(23(18)3)16-24-11-13-25(14-12-24)20-7-5-6-8-21(20)27-4/h5-10H,11-16H2,1-4H3 BJNGJVFHWCCTQX-UHFFFAOYSA-N 50029261 N-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-N-methyl-acetamide;succinate D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029261&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10714235 103938332 ZINC13743832 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774160 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)C(=O)C3CCCCC3)n2C)CC1 InChI=1S/C30H46N4O2/c1-23(2)34(30(35)25-11-7-6-8-12-25)22-27-16-15-26(31(27)5)21-32-17-19-33(20-18-32)28-13-9-10-14-29(28)36-24(3)4/h9-10,13-16,23-25H,6-8,11-12,17-22H2,1-5H3 ZBHZVMMPAAMZQJ-UHFFFAOYSA-N 50029272 Cyclohexanecarboxylic acid {5-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-isopropyl-amide;succinate D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029272&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10601281 103938343 ZINC13743836 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774161 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C)S(=O)(=O)C(C)C)n2C)CC1 InChI=1S/C24H38N4O3S/c1-19(2)31-24-10-8-7-9-23(24)28-15-13-27(14-16-28)18-22-12-11-21(26(22)6)17-25(5)32(29,30)20(3)4/h7-12,19-20H,13-18H2,1-6H3 PDFYNWDLYVXERX-UHFFFAOYSA-N 50029273 Propane-2-sulfonic acid {5-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-methyl-amide;succinate D(2) dopamine receptor Rattus norvegicus 72 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029273&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10671748 103938344 ZINC13743844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774162 CC(C)Oc1ccccc1N1CCN(Cc2cc(cs2)C(=O)N2CCCCCC2)CC1 InChI=1S/C25H35N3O2S/c1-20(2)30-24-10-6-5-9-23(24)27-15-13-26(14-16-27)18-22-17-21(19-31-22)25(29)28-11-7-3-4-8-12-28/h5-6,9-10,17,19-20H,3-4,7-8,11-16,18H2,1-2H3 MLVIALUSOLQJGR-UHFFFAOYSA-N 50029268 Azepan-1-yl-{5-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-thiophen-3-yl}-methanone; hydrochloride::CHEMBL544373 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029268&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10551162 103938339 CHEMBL544373 ZINC53046165 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774163 CCCCC(=O)N(C)Cc1ccc(CN2CCN(CC2)c2ccccc2OC(C)C)n1C InChI=1S/C26H40N4O2/c1-6-7-12-26(31)27(4)19-22-13-14-23(28(22)5)20-29-15-17-30(18-16-29)24-10-8-9-11-25(24)32-21(2)3/h8-11,13-14,21H,6-7,12,15-20H2,1-5H3 IMUYDTCACMPZTB-UHFFFAOYSA-N 50029262 Pentanoic acid {5-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-methyl-amide;succinate D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029262&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10789252 103938333 ZINC13743834 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774165 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCCC3=O)o2)CC1 InChI=1S/C25H35N3O3/c1-20(2)30-24-9-6-5-8-23(24)27-16-14-26(15-17-27)18-21-11-12-22(31-21)19-28-13-7-3-4-10-25(28)29/h5-6,8-9,11-12,20H,3-4,7,10,13-19H2,1-2H3 ATCDHNZWZSXBNA-UHFFFAOYSA-N 50029269 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-furan-2-ylmethyl}-azepan-2-one;succinate D(2) dopamine receptor Rattus norvegicus 122 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029269&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717291 103938340 ZINC13743850 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774166 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)C(=O)C(C)C)n2C)CC1 InChI=1S/C27H42N4O2/c1-20(2)27(32)31(21(3)4)19-24-13-12-23(28(24)7)18-29-14-16-30(17-15-29)25-10-8-9-11-26(25)33-22(5)6/h8-13,20-22H,14-19H2,1-7H3 GEUOQLMWWHJSIO-UHFFFAOYSA-N 50029267 N-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-N-isopropyl-isobutyramide;succinate D(2) dopamine receptor Rattus norvegicus 81 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029267&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10695046 103938338 ZINC13743837 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774167 CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)no2)CC1 InChI=1S/C23H32N4O3/c1-18(2)29-22-8-4-3-7-21(22)26-13-11-25(12-14-26)17-20-15-19(24-30-20)16-27-10-6-5-9-23(27)28/h3-4,7-8,15,18H,5-6,9-14,16-17H2,1-2H3 DXYQOKKQRDKQCQ-UHFFFAOYSA-N 50029266 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-isoxazol-3-ylmethyl}-piperidin-2-one; hydrochloride::CHEMBL538529::CHEMBL81093 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029266&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811627 103938337 CHEMBL538529CHEMBL81093 ZINC13743857 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774173 CC(C)Oc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCCCC3)n2C)CC1 InChI=1S/C27H38N4O3/c1-21(2)34-25-10-6-5-9-23(25)30-19-17-29(18-20-30)16-13-22-11-12-24(28(22)3)26(32)27(33)31-14-7-4-8-15-31/h5-6,9-12,21H,4,7-8,13-20H2,1-3H3 JQLMLBWCNWQARH-UHFFFAOYSA-N 50029245 1-(5-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-ethyl}-1-methyl-1H-pyrrol-2-yl)-2-piperidin-1-yl-ethane-1,2-dione;succinate D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029245&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10647917 103938316 ZINC13743828 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774175 COc1ccccc1N1CCN(CCc2ccc(C(=O)C(=O)N3CCCCC3)n2C)CC1 InChI=1S/C25H34N4O3/c1-26-20(10-11-22(26)24(30)25(31)29-13-6-3-7-14-29)12-15-27-16-18-28(19-17-27)21-8-4-5-9-23(21)32-2/h4-5,8-11H,3,6-7,12-19H2,1-2H3 MQEMNNSHSPSDOJ-UHFFFAOYSA-N 50029256 1-(5-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-1-methyl-1H-pyrrol-2-yl)-2-piperidin-1-yl-ethane-1,2-dione;succinate D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10622890 103938327 ZINC13743825 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774180 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)s2)CC1 InChI=1S/C24H33N3O2S/c1-19(2)29-23-8-4-3-7-22(23)26-15-13-25(14-16-26)17-20-10-11-21(30-20)18-27-12-6-5-9-24(27)28/h3-4,7-8,10-11,19H,5-6,9,12-18H2,1-2H3 INRFQTYFEDZXNB-UHFFFAOYSA-N 50029275 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-thiophen-2-ylmethyl}-piperidin-2-one; hydrochloride::CHEMBL305029::CHEMBL552830 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029275&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10836245 103938346 CHEMBL305029CHEMBL552830 ZINC53084058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774181 COc1ccccc1N1CCN(Cc2ccc(CN3CCCCCC3=O)o2)CC1 InChI=1S/C23H31N3O3/c1-28-22-8-5-4-7-21(22)25-15-13-24(14-16-25)17-19-10-11-20(29-19)18-26-12-6-2-3-9-23(26)27/h4-5,7-8,10-11H,2-3,6,9,12-18H2,1H3 PSYJSPSKWQDAMM-UHFFFAOYSA-N 50029276 1-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-furan-2-ylmethyl}-azepan-2-one;succinate D(2) dopamine receptor Rattus norvegicus 167 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029276&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10430929 103938347 ZINC12356314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774182 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CCN3CCCCC3=O)n2C)CC1 InChI=1S/C26H38N4O2/c1-21(2)32-25-9-5-4-8-24(25)29-18-16-28(17-19-29)20-23-12-11-22(27(23)3)13-15-30-14-7-6-10-26(30)31/h4-5,8-9,11-12,21H,6-7,10,13-20H2,1-3H3 GHSIPNWAVPZPAC-UHFFFAOYSA-N 50029283 1-(2-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-yl}-ethyl)-piperidin-2-one; hydrochloride::CHEMBL543900 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10670681 103938354 CHEMBL543900 ZINC53046120 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774183 O=C(N1CCCCC1)c1ccc(CN2CCN(CC2)c2cccc3ccoc23)s1 InChI=1S/C23H27N3O2S/c27-23(26-10-2-1-3-11-26)21-8-7-19(29-21)17-24-12-14-25(15-13-24)20-6-4-5-18-9-16-28-22(18)20/h4-9,16H,1-3,10-15,17H2 DWMODKKMMSDCPG-UHFFFAOYSA-N 50029280 CHEMBL544371::[5-(4-Benzofuran-7-yl-piperazin-1-ylmethyl)-thiophen-2-yl]-piperidin-1-yl-methanone; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10787677 103938351 CHEMBL544371 ZINC13743847 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774185 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C)C(=O)C(C)C)n2C)CC1 InChI=1S/C25H38N4O2/c1-19(2)25(30)26(5)17-21-11-12-22(27(21)6)18-28-13-15-29(16-14-28)23-9-7-8-10-24(23)31-20(3)4/h7-12,19-20H,13-18H2,1-6H3 WCBYKNPMNGMTAF-UHFFFAOYSA-N 50029277 N-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-N-methyl-isobutyramide;succinate D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11796704 103938348 ZINC13743831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774187 COc1ccccc1N1CCN(Cc2ccc(CN(C)S(C)(=O)=O)n2C)CC1 InChI=1S/C20H30N4O3S/c1-21(28(4,25)26)15-17-9-10-18(22(17)2)16-23-11-13-24(14-12-23)19-7-5-6-8-20(19)27-3/h5-10H,11-16H2,1-4H3 NJDFRQKTRCSZSA-UHFFFAOYSA-N 50029289 N-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-N-methyl-methanesulfonamide;succinate D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795639 103938360 ZINC13743839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774189 COc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)C(=O)C3CCCCC3)n2C)CC1 InChI=1S/C28H42N4O2/c1-22(2)32(28(33)23-10-6-5-7-11-23)21-25-15-14-24(29(25)3)20-30-16-18-31(19-17-30)26-12-8-9-13-27(26)34-4/h8-9,12-15,22-23H,5-7,10-11,16-21H2,1-4H3 UEDDZPVNPJCYEH-UHFFFAOYSA-N 50029282 Cyclohexanecarboxylic acid isopropyl-{5-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-amide;succinate D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11798444 103938353 ZINC13743835 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774190 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)o2)CC1 InChI=1S/C24H33N3O3/c1-19(2)29-23-8-4-3-7-22(23)26-15-13-25(14-16-26)17-20-10-11-21(30-20)18-27-12-6-5-9-24(27)28/h3-4,7-8,10-11,19H,5-6,9,12-18H2,1-2H3 YDSCQKKEAORCNL-UHFFFAOYSA-N 50029243 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-furan-2-ylmethyl}-piperidin-2-one;succinate D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029243&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10716573 103938314 ZINC13743848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774191 COc1ccccc1N1CCN(Cc2ccc(CNC(C)=O)n2C)CC1 InChI=1S/C20H28N4O2/c1-16(25)21-14-17-8-9-18(22(17)2)15-23-10-12-24(13-11-23)19-6-4-5-7-20(19)26-3/h4-9H,10-15H2,1-3H3,(H,21,25) KGIFFESZRLFDSD-UHFFFAOYSA-N 50029284 N-{5-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-acetamide;succinate D(2) dopamine receptor Rattus norvegicus >30 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029284&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10546191 103938355 ZINC13743860 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774192 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCCCC3=O)o2)CC1 InChI=1S/C26H37N3O3/c1-21(2)31-25-10-7-6-9-24(25)28-17-15-27(16-18-28)19-22-12-13-23(32-22)20-29-14-8-4-3-5-11-26(29)30/h6-7,9-10,12-13,21H,3-5,8,11,14-20H2,1-2H3 MRNMCWDQIHUANA-UHFFFAOYSA-N 50029285 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-furan-2-ylmethyl}-azocan-2-one;succinate D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029285&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10622938 103938356 ZINC13743851 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774193 CC(C)Oc1ccccc1N1CCN(Cc2cc(CO)no2)CC1 InChI=1S/C18H25N3O3/c1-14(2)23-18-6-4-3-5-17(18)21-9-7-20(8-10-21)12-16-11-15(13-22)19-24-16/h3-6,11,14,22H,7-10,12-13H2,1-2H3 VQWUSRRSHHAZMT-UHFFFAOYSA-N 50029281 CHEMBL334889::{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-isoxazol-3-yl}-methanol D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640259 103938352 CHEMBL334889 ZINC13743864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774194 CCCCS(=O)(=O)N(C)Cc1ccc(CN2CCN(CC2)c2ccccc2OC)n1C InChI=1S/C23H36N4O3S/c1-5-6-17-31(28,29)24(2)18-20-11-12-21(25(20)3)19-26-13-15-27(16-14-26)22-9-7-8-10-23(22)30-4/h7-12H,5-6,13-19H2,1-4H3 PKAPZYACIIBQND-UHFFFAOYSA-N 50029286 Butane-1-sulfonic acid {5-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-methyl-amide;succinate D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10647156 103938357 ZINC13743843 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774195 COc1ccccc1N1CCN(CCc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C24H34N4O2/c1-25-20(10-11-21(25)19-28-13-6-5-9-24(28)29)12-14-26-15-17-27(18-16-26)22-7-3-4-8-23(22)30-2/h3-4,7-8,10-11H,5-6,9,12-19H2,1-2H3 GWLNFZHDKJSSLQ-UHFFFAOYSA-N 50029253 1-(5-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-1-methyl-1H-pyrrol-2-ylmethyl)-piperidin-2-one;succinate D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029253&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11795860 103938324 ZINC12356362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774198 CC(C)Oc1ccccc1N1CCN(CC2CC(CO)=NO2)CC1 InChI=1S/C18H27N3O3/c1-14(2)23-18-6-4-3-5-17(18)21-9-7-20(8-10-21)12-16-11-15(13-22)19-24-16/h3-6,14,16,22H,7-13H2,1-2H3 XQPJKVCGLUSCMJ-UHFFFAOYSA-N 50029290 CHEMBL133880::{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-4,5-dihydro-isoxazol-3-yl}-methanol D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10782882 103938361 CHEMBL133880 ZINC13743854 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774200 CC(C)Oc1ccccc1N1CCN(CCc2ccc(CN3CCCCC3=O)n2C)CC1 InChI=1S/C26H38N4O2/c1-21(2)32-25-9-5-4-8-24(25)29-18-16-28(17-19-29)15-13-22-11-12-23(27(22)3)20-30-14-7-6-10-26(30)31/h4-5,8-9,11-12,21H,6-7,10,13-20H2,1-3H3 GGAUGSHUWKTQAH-UHFFFAOYSA-N 50029278 1-(5-{2-[4-(2-Isopropoxy-phenyl)-piperazin-1-yl]-ethyl}-1-methyl-1H-pyrrol-2-ylmethyl)-piperidin-2-one;succinate D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029278&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10252601 103938349 ZINC13743829 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774201 CCCCC(=O)N(C)Cc1ccc(CN2CCN(CC2)c2ccccc2OC)n1C InChI=1S/C24H36N4O2/c1-5-6-11-24(29)25(2)18-20-12-13-21(26(20)3)19-27-14-16-28(17-15-27)22-9-7-8-10-23(22)30-4/h7-10,12-13H,5-6,11,14-19H2,1-4H3 RNDCMHYDTXTBFA-UHFFFAOYSA-N 50029247 Pentanoic acid {5-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-methyl-amide;succinate D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669385 103938318 ZINC13743833 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774206 CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN(C)C(C)=O)n2C)CC1 InChI=1S/C23H34N4O2/c1-18(2)29-23-9-7-6-8-22(23)27-14-12-26(13-15-27)17-21-11-10-20(25(21)5)16-24(4)19(3)28/h6-11,18H,12-17H2,1-5H3 ZIOSSBQRBPKWQN-UHFFFAOYSA-N 50029271 N-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-N-methyl-acetamide;succinate D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029271&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10763417 103938342 ZINC13743830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774207 CC(C)Oc1ccccc1N1CCN(CC2CC(CN3CCCCC3=O)=NO2)CC1 InChI=1S/C23H34N4O3/c1-18(2)29-22-8-4-3-7-21(22)26-13-11-25(12-14-26)17-20-15-19(24-30-20)16-27-10-6-5-9-23(27)28/h3-4,7-8,18,20H,5-6,9-17H2,1-2H3 LJTAXDQCGDWIMS-UHFFFAOYSA-N 50029291 1-{5-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-4,5-dihydro-isoxazol-3-ylmethyl}-piperidin-2-one::CHEMBL124285 D(2) dopamine receptor Rattus norvegicus 1841 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029291&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10549731 103938362 CHEMBL124285 ZINC13743856 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774208 COc1ccccc1N1CCN(Cc2ccc(CN(Cc3ccccc3)C(C)=O)n2C)CC1 InChI=1S/C27H34N4O2/c1-22(32)31(19-23-9-5-4-6-10-23)21-25-14-13-24(28(25)2)20-29-15-17-30(18-16-29)26-11-7-8-12-27(26)33-3/h4-14H,15-21H2,1-3H3 GYDBESXMPQTKHX-UHFFFAOYSA-N 50029293 N-Benzyl-N-{5-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-acetamide;succinate D(2) dopamine receptor Rattus norvegicus >30 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10623269 103938364 ZINC13743858 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50774210 COc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)S(C)(=O)=O)n2C)CC1 InChI=1S/C22H34N4O3S/c1-18(2)26(30(5,27)28)17-20-11-10-19(23(20)3)16-24-12-14-25(15-13-24)21-8-6-7-9-22(21)29-4/h6-11,18H,12-17H2,1-5H3 YYEYFORNJDYHJH-UHFFFAOYSA-N 50029292 CHEMBL435198::N-Isopropyl-N-{5-[4-(2-methoxy-phenyl)-piperazin-1-ylmethyl]-1-methyl-1H-pyrrol-2-ylmethyl}-methanesulfonamide D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00021a009 10.7270/Q2GX4C61 7473547 Scott, MK; Baxter, EW; Bennett, DJ; Boyd, RE; Blum, PS; Codd, EE; Kukla, MJ; Malloy, E; Maryanoff, BE; Maryanoff, CA R. W. Johnson Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50029292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50029292&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10526838 103938363 CHEMBL435198 ZINC13743862 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777740 CC1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1csc2cc(F)ccc12 InChI=1S/C24H32FN3OS2/c1-18-28(23(29)24(31-18)8-2-3-9-24)11-5-4-10-26-12-14-27(15-13-26)21-17-30-22-16-19(25)6-7-20(21)22/h6-7,16-18H,2-5,8-15H2,1H3 SYTKLFTVOOOLQR-UHFFFAOYSA-N 50053691 3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-2-methyl-1-thia-3-aza-spiro[4.4]nonan-4-one::CHEMBL131482 D(2) dopamine receptor Rattus norvegicus 954 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053691&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10411988 103950370 CHEMBL131482 ZINC03929032 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777746 Clc1ccccc1N1CCN(CCCCN2CSCC2=O)CC1 InChI=1S/C17H24ClN3OS/c18-15-5-1-2-6-16(15)20-11-9-19(10-12-20)7-3-4-8-21-14-23-13-17(21)22/h1-2,5-6H,3-4,7-14H2 SDWFDYMHGVJAFB-UHFFFAOYSA-N 50053696 3-{4-[4-(2-Chloro-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL130822 D(2) dopamine receptor Rattus norvegicus 652 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053696&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10831935 103950375 CHEMBL130822 ZINC13759362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777748 CC1(C)SCN(CCCCN2CCN(CC2)c2cn(-c3ccc(F)cc3)c3ccccc23)C1=O InChI=1S/C27H33FN4OS/c1-27(2)26(33)31(20-34-27)14-6-5-13-29-15-17-30(18-16-29)25-19-32(22-11-9-21(28)10-12-22)24-8-4-3-7-23(24)25/h3-4,7-12,19H,5-6,13-18,20H2,1-2H3 YMSOKXWNHGAVTP-UHFFFAOYSA-N 50053695 3-(4-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperazin-1-yl}-butyl)-5,5-dimethyl-thiazolidin-4-one::CHEMBL130894 D(2) dopamine receptor Rattus norvegicus 131 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053695&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10790896 103950374 CHEMBL130894 ZINC13759409 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777750 COc1ccccc1N1CCN(CCCCN2CSC(C)C2=O)CC1 InChI=1S/C19H29N3O2S/c1-16-19(23)22(15-25-16)10-6-5-9-20-11-13-21(14-12-20)17-7-3-4-8-18(17)24-2/h3-4,7-8,16H,5-6,9-15H2,1-2H3 BOYYCGOYSQSWQQ-UHFFFAOYSA-N 50053699 3-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-5-methyl-thiazolidin-4-one::CHEMBL337292 D(2) dopamine receptor Rattus norvegicus 786 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053699&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10808722 103950378 CHEMBL337292 ZINC13759344 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777751 CC1(C)SCC(=O)N1CCCCN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C19H28ClN3OS/c1-19(2)23(18(24)15-25-19)9-4-3-8-21-10-12-22(13-11-21)17-7-5-6-16(20)14-17/h5-7,14H,3-4,8-13,15H2,1-2H3 GDXNZCBYCYZCGF-UHFFFAOYSA-N 50053697 3-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-2,2-dimethyl-thiazolidin-4-one::CHEMBL128242 D(2) dopamine receptor Rattus norvegicus 835 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053697&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11794256 103950376 CHEMBL128242 ZINC13759368 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777755 Clc1cccc(c1)N1CCN(CCCCN2CSCC2=O)CC1 InChI=1S/C17H24ClN3OS/c18-15-4-3-5-16(12-15)20-10-8-19(9-11-20)6-1-2-7-21-14-23-13-17(21)22/h3-5,12H,1-2,6-11,13-14H2 GLXMUWITVSVHQW-UHFFFAOYSA-N 50053703 3-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL128041 D(2) dopamine receptor Rattus norvegicus 2210 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053703&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10831936 103950382 CHEMBL128041 ZINC13759363 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777763 CC1SC(C)(C)C(=O)N1CCCCN1CCN(CC1)c1cn(-c2ccc(F)cc2)c2ccccc12 InChI=1S/C28H35FN4OS/c1-21-32(27(34)28(2,3)35-21)15-7-6-14-30-16-18-31(19-17-30)26-20-33(23-12-10-22(29)11-13-23)25-9-5-4-8-24(25)26/h4-5,8-13,20-21H,6-7,14-19H2,1-3H3 YGZBJEJSQMGESX-UHFFFAOYSA-N 50053709 3-(4-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperazin-1-yl}-butyl)-2,5,5-trimethyl-thiazolidin-4-one::CHEMBL334986 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053709&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10815075 103950388 CHEMBL334986 ZINC13759418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777765 Cc1cccc(N2CCN(CCCCN3CSC(C)(C)C3=O)CC2)c1C InChI=1S/C21H33N3OS/c1-17-8-7-9-19(18(17)2)23-14-12-22(13-15-23)10-5-6-11-24-16-26-21(3,4)20(24)25/h7-9H,5-6,10-16H2,1-4H3 VMHMLZRBBSLFOO-UHFFFAOYSA-N 50053707 3-{4-[4-(2,3-Dimethyl-phenyl)-piperazin-1-yl]-butyl}-5,5-dimethyl-thiazolidin-4-one::CHEMBL130290 D(2) dopamine receptor Rattus norvegicus 916 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053707&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10833320 103950386 CHEMBL130290 ZINC13759360 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777770 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 158 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777772 Cc1ccccc1N1CCN(CCCCN2CSCC2=O)CC1 InChI=1S/C18H27N3OS/c1-16-6-2-3-7-17(16)20-12-10-19(11-13-20)8-4-5-9-21-15-23-14-18(21)22/h2-3,6-7H,4-5,8-15H2,1H3 TZUNRCMCHCTVRE-UHFFFAOYSA-N 50053716 3-[4-(4-o-Tolyl-piperazin-1-yl)-butyl]-thiazolidin-4-one::CHEMBL129924 D(2) dopamine receptor Rattus norvegicus 1610 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053716&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10664387 103950395 CHEMBL129924 ZINC13759353 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777776 O=C1N(CCCCN2CCN(CC2)c2csc3ccccc23)CSC11CCCC1 InChI=1S/C23H31N3OS2/c27-22-23(9-3-4-10-23)29-18-26(22)12-6-5-11-24-13-15-25(16-14-24)20-17-28-21-8-2-1-7-19(20)21/h1-2,7-8,17H,3-6,9-16,18H2 RZEWAVWSTBUNFZ-UHFFFAOYSA-N 50053715 3-[4-(4-Benzo[b]thiophen-3-yl-piperazin-1-yl)-butyl]-1-thia-3-aza-spiro[4.4]nonan-4-one::CHEMBL336967 D(2) dopamine receptor Rattus norvegicus 244 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053715&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574631 103950394 CHEMBL336967 ZINC13759429 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777782 CC1(C)SCC(=O)N1CCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F InChI=1S/C20H28F3N3OS/c1-19(2)26(18(27)15-28-19)9-4-3-8-24-10-12-25(13-11-24)17-7-5-6-16(14-17)20(21,22)23/h5-7,14H,3-4,8-13,15H2,1-2H3 VHBJVHRRBQCXMZ-UHFFFAOYSA-N 50053719 2,2-Dimethyl-3-{4-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL334585 D(2) dopamine receptor Rattus norvegicus 1130 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053719&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10597952 103950398 CHEMBL334585 ZINC13759351 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777783 O=C1CSCN1CCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C18H24N4OS2/c23-17-13-24-14-22(17)8-4-3-7-20-9-11-21(12-10-20)18-15-5-1-2-6-16(15)25-19-18/h1-2,5-6H,3-4,7-14H2 ZVDGCNAUCPQLCE-UHFFFAOYSA-N 50053705 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-thiazolidin-4-one::CHEMBL339852 D(2) dopamine receptor Rattus norvegicus 224 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053705&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809567 103950384 CHEMBL339852 ZINC12356152 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777784 CC1SC(C)(C)C(=O)N1CCCCN1CCN(CC1)c1cn(-c2ccccc2)c2cc(F)ccc12 InChI=1S/C28H35FN4OS/c1-21-32(27(34)28(2,3)35-21)14-8-7-13-30-15-17-31(18-16-30)26-20-33(23-9-5-4-6-10-23)25-19-22(29)11-12-24(25)26/h4-6,9-12,19-21H,7-8,13-18H2,1-3H3 JESULJQFGFJISO-UHFFFAOYSA-N 50053718 3-{4-[4-(6-Fluoro-1-phenyl-1H-indol-3-yl)-piperazin-1-yl]-butyl}-2,5,5-trimethyl-thiazolidin-4-one::CHEMBL132048 D(2) dopamine receptor Rattus norvegicus 1090 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053718&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10767522 103950397 CHEMBL132048 ZINC13759421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777785 CC(C)(O)C1SCN(CCCCN2CCN(CC2)c2csc3cc(F)ccc23)C1=O InChI=1S/C22H30FN3O2S2/c1-22(2,28)20-21(27)26(15-30-20)8-4-3-7-24-9-11-25(12-10-24)18-14-29-19-13-16(23)5-6-17(18)19/h5-6,13-14,20,28H,3-4,7-12,15H2,1-2H3 QYJJLSBKUVWTLC-UHFFFAOYSA-N 50053720 3-{4-[4-(6-Fluoro-benzo[b]thiophen-3-yl)-piperazin-1-yl]-butyl}-5-(1-hydroxy-1-methyl-ethyl)-thiazolidin-4-one::CHEMBL131546 D(2) dopamine receptor Rattus norvegicus 453 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053720&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10694912 103950399 CHEMBL131546 ZINC13759437 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777786 CC1(C)SCN(CCCCN2CCN(CC2)c2cc3ccccc3cn2)C1=O InChI=1S/C22H30N4OS/c1-22(2)21(27)26(17-28-22)10-6-5-9-24-11-13-25(14-12-24)20-15-18-7-3-4-8-19(18)16-23-20/h3-4,7-8,15-16H,5-6,9-14,17H2,1-2H3 FBYKATSGAJCQQW-UHFFFAOYSA-N 50053713 3-[4-(4-Isoquinolin-3-yl-piperazin-1-yl)-butyl]-5,5-dimethyl-thiazolidin-4-one::CHEMBL130489 D(2) dopamine receptor Rattus norvegicus 8430 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053713&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10501072 103950392 CHEMBL130489 ZINC12356241 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777788 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777791 CC1(C)SCN(CCCCN2CCN(CC2)c2nsc3ccccc23)C1=O InChI=1S/C20H28N4OS2/c1-20(2)19(25)24(15-26-20)10-6-5-9-22-11-13-23(14-12-22)18-16-7-3-4-8-17(16)27-21-18/h3-4,7-8H,5-6,9-15H2,1-2H3 XDZLVBHRWNCMQE-UHFFFAOYSA-N 50053724 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-5,5-dimethyl-thiazolidin-4-one::CHEMBL130788 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10668966 103950403 CHEMBL130788 ZINC01547049 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777792 Cc1cccc(c1)N1CCN(CCCCN2C(=O)C(C)(C)SC2(C)C)CC1 InChI=1S/C22H35N3OS/c1-18-9-8-10-19(17-18)24-15-13-23(14-16-24)11-6-7-12-25-20(26)21(2,3)27-22(25,4)5/h8-10,17H,6-7,11-16H2,1-5H3 NXIBWRISYQVGKI-UHFFFAOYSA-N 50053712 2,2,5,5-Tetramethyl-3-[4-(4-m-tolyl-piperazin-1-yl)-butyl]-thiazolidin-4-one::CHEMBL132901 D(2) dopamine receptor Rattus norvegicus 1840 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053712&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10572440 103950391 CHEMBL132901 ZINC13759357 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777794 Clc1ccc2c(nsc2c1)N1CCN(CCCCN2CSC3(CCCCC3)C2=O)CC1 InChI=1S/C23H31ClN4OS2/c24-18-6-7-19-20(16-18)31-25-21(19)27-14-12-26(13-15-27)10-4-5-11-28-17-30-23(22(28)29)8-2-1-3-9-23/h6-7,16H,1-5,8-15,17H2 BGLIAMFGDBYXHI-UHFFFAOYSA-N 50053723 3-{4-[4-(6-Chloro-benzo[d]isothiazol-3-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.5]decan-4-one::CHEMBL132334 D(2) dopamine receptor Rattus norvegicus 671 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053723&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11798884 103950402 CHEMBL132334 ZINC13759404 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777796 Clc1ccc(cc1)N1CCN(CCCCN2CSCC2=O)CC1 InChI=1S/C17H24ClN3OS/c18-15-3-5-16(6-4-15)20-11-9-19(10-12-20)7-1-2-8-21-14-23-13-17(21)22/h3-6H,1-2,7-14H2 BVQFKTWXDRMYOH-UHFFFAOYSA-N 50053693 3-{4-[4-(4-Chloro-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL132783 D(2) dopamine receptor Rattus norvegicus 8760 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10665799 103950372 CHEMBL132783 ZINC01547053 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777797 CC1SCC(=O)N1CCCCN1CCN(CC1)c1cccc(Cl)c1 InChI=1S/C18H26ClN3OS/c1-15-22(18(23)14-24-15)8-3-2-7-20-9-11-21(12-10-20)17-6-4-5-16(19)13-17/h4-6,13,15H,2-3,7-12,14H2,1H3 PYSHHWRNGOOSFR-UHFFFAOYSA-N 50053721 3-{4-[4-(3-Chloro-phenyl)-piperazin-1-yl]-butyl}-2-methyl-thiazolidin-4-one::CHEMBL339237 D(2) dopamine receptor Rattus norvegicus 2230 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053721&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10571019 103950400 CHEMBL339237 ZINC13759367 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777799 FC(F)(F)CC1SCN(CCCCN2CCN(CC2)c2nsc3ccccc23)C1=O InChI=1S/C20H25F3N4OS2/c21-20(22,23)13-17-19(28)27(14-29-17)8-4-3-7-25-9-11-26(12-10-25)18-15-5-1-2-6-16(15)30-24-18/h1-2,5-6,17H,3-4,7-14H2 UCUYUQLHQLTCSM-UHFFFAOYSA-N 50053728 3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-5-(2,2,2-trifluoro-ethyl)-thiazolidin-4-one::CHEMBL336376 D(2) dopamine receptor Rattus norvegicus 136 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053728&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11798129 103950407 CHEMBL336376 ZINC13759389 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777800 Fc1ccc(cc1)-n1cc(N2CCN(CCCCN3CSC4(CCCCC4)C3=O)CC2)c2ccccc12 InChI=1S/C30H37FN4OS/c31-24-10-12-25(13-11-24)35-22-28(26-8-2-3-9-27(26)35)33-20-18-32(19-21-33)16-6-7-17-34-23-37-30(29(34)36)14-4-1-5-15-30/h2-3,8-13,22H,1,4-7,14-21,23H2 CSGPIHKZIYRGPO-UHFFFAOYSA-N 50053702 3-(4-{4-[1-(4-Fluoro-phenyl)-1H-indol-3-yl]-piperazin-1-yl}-butyl)-1-thia-3-aza-spiro[4.5]decan-4-one::CHEMBL131159 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053702&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10768312 103950381 CHEMBL131159 ZINC13759426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777805 O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)CSC11Cc2ccccc2C1 InChI=1S/C26H30N4OS2/c31-25-26(17-20-7-1-2-8-21(20)18-26)32-19-30(25)12-6-5-11-28-13-15-29(16-14-28)24-22-9-3-4-10-23(22)33-27-24/h1-4,7-10H,5-6,11-19H2 KNKQFICBNCXQPO-UHFFFAOYSA-N 50053725 3'-[4-(4-benzo[d]isothiazol-3-ylhexahydro-1-pyrazinyl)butyl]spiro[2,3-dihydro-1H-indene-2,5'-(tetrahydro[1,3]thiazolane)]-4'-one::CHEMBL334477 D(2) dopamine receptor Rattus norvegicus 697 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053725&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10672329 103950404 CHEMBL334477 ZINC13759395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777806 CC1SC2(CCCC2)C(=O)N1CCCCN1CCN(CC1)c1cn(-c2ccccc2)c2ccccc12 InChI=1S/C30H38N4OS/c1-24-33(29(35)30(36-24)15-7-8-16-30)18-10-9-17-31-19-21-32(22-20-31)28-23-34(25-11-3-2-4-12-25)27-14-6-5-13-26(27)28/h2-6,11-14,23-24H,7-10,15-22H2,1H3 SSJMCDCGDWFBTC-UHFFFAOYSA-N 50053698 2-Methyl-3-{4-[4-(1-phenyl-1H-indol-3-yl)-piperazin-1-yl]-butyl}-1-thia-3-aza-spiro[4.4]nonan-4-one::CHEMBL130624 D(2) dopamine receptor Rattus norvegicus 356 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053698&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10744055 103950377 CHEMBL130624 ZINC13759423 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777809 COc1cccc(c1)N1CCN(CCCCN2CSCC2=O)CC1 InChI=1S/C18H27N3O2S/c1-23-17-6-4-5-16(13-17)20-11-9-19(10-12-20)7-2-3-8-21-15-24-14-18(21)22/h4-6,13H,2-3,7-12,14-15H2,1H3 XIRFEUQHJWCXCM-UHFFFAOYSA-N 50053726 3-{4-[4-(3-Methoxy-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL339015 D(2) dopamine receptor Rattus norvegicus 7490 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10569822 103950405 CHEMBL339015 ZINC13759348 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777812 Fc1ccc(cc1)N1CCN(CCCCN2CSCC2=O)CC1 InChI=1S/C17H24FN3OS/c18-15-3-5-16(6-4-15)20-11-9-19(10-12-20)7-1-2-8-21-14-23-13-17(21)22/h3-6H,1-2,7-14H2 KMJQEKNRQDMGCF-UHFFFAOYSA-N 50053717 3-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL132993 D(2) dopamine receptor Rattus norvegicus 12900 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053717&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10759394 103950396 CHEMBL132993 ZINC12356078 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777814 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2CSCC2=O)CC1 InChI=1S/C18H24F3N3OS/c19-18(20,21)15-4-3-5-16(12-15)23-10-8-22(9-11-23)6-1-2-7-24-14-26-13-17(24)25/h3-5,12H,1-2,6-11,13-14H2 SUIWRRCXSBMAQI-UHFFFAOYSA-N 50053727 3-{4-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL130677 D(2) dopamine receptor Rattus norvegicus 1960 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053727&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10715251 103950406 CHEMBL130677 ZINC13759350 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50777815 Cc1cccc(N2CCN(CCCCN3CSCC3=O)CC2)c1C InChI=1S/C19H29N3OS/c1-16-6-5-7-18(17(16)2)21-12-10-20(11-13-21)8-3-4-9-22-15-24-14-19(22)23/h5-7H,3-4,8-15H2,1-2H3 NDHQLVTVKGJPKD-UHFFFAOYSA-N 50053722 3-{4-[4-(2,3-Dimethyl-phenyl)-piperazin-1-yl]-butyl}-thiazolidin-4-one::CHEMBL132825 D(2) dopamine receptor Rattus norvegicus 778 ChEMBL 10.1021/jm960268u 10.7270/Q2ST7QH3 8831770 Hrib, NJ; Jurcak, JG; Bregna, DE; Burgher, KL; Hartman, HB; Kafka, S; Kerman, LL; Kongsamut, S; Roehr, JE; Szewczak, MR; Woods-Kettelberger, AT; Corbett, R Hoechst Marion Roussel Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50053722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50053722&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10665353 103950401 CHEMBL132825 ZINC01547052 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779462 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 17000 ChEMBL 10.1021/jm950447w 10.7270/Q2XG9RT3 8632409 Brusniak, MY; Pearlman, RS; Neve, KA; Wilcox, RE VA Medical Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779472 Nc1cccc(c1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H27N5OS/c23-18-7-5-6-17(16-18)22(28)24-10-3-4-11-26-12-14-27(15-13-26)21-19-8-1-2-9-20(19)29-25-21/h1-2,5-9,16H,3-4,10-15,23H2,(H,24,28) WJSAYEHWTNTFPM-UHFFFAOYSA-N 50051244 3-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-benzamide; hydrochloride::CHEMBL554640 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051244&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10811491 103948242 CHEMBL554640 ZINC13747143 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779485 CC(C)(C)OC(=O)Nc1cccc(c1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C27H35N5O3S/c1-27(2,3)35-26(34)29-21-10-8-9-20(19-21)25(33)28-13-6-7-14-31-15-17-32(18-16-31)24-22-11-4-5-12-23(22)36-30-24/h4-5,8-12,19H,6-7,13-18H2,1-3H3,(H,28,33)(H,29,34) RLABTUZUPMOGFQ-UHFFFAOYSA-N 50051256 CHEMBL556030::{3-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butylcarbamoyl]-phenyl}-carbamic acid tert-butyl ester; hydrochloride D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10601758 103948254 CHEMBL556030 ZINC13747135 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779489 Nc1c(F)cccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H26FN5OS/c23-18-8-5-7-17(20(18)24)22(29)25-10-3-4-11-27-12-14-28(15-13-27)21-16-6-1-2-9-19(16)30-26-21/h1-2,5-9H,3-4,10-15,24H2,(H,25,29) PJBGKTDMNYSFJA-UHFFFAOYSA-N 50051259 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3-fluoro-benzamide; hydrochloride::CHEMBL556788 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051259&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10812407 103948257 CHEMBL556788 ZINC13747185 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779490 Clc1cc(Cl)cc(c1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H24Cl2N4OS/c23-17-13-16(14-18(24)15-17)22(29)25-7-3-4-8-27-9-11-28(12-10-27)21-19-5-1-2-6-20(19)30-26-21/h1-2,5-6,13-15H,3-4,7-12H2,(H,25,29) BBNXODGVQYYUAP-UHFFFAOYSA-N 50051261 CHEMBL537025::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-3,5-dichloro-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051261 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051261&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44271816 103948259 CHEMBL537025 ZINC13747164 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779491 CNc1ccccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C23H29N5OS/c1-24-20-10-4-2-8-18(20)23(29)25-12-6-7-13-27-14-16-28(17-15-27)22-19-9-3-5-11-21(19)30-26-22/h2-5,8-11,24H,6-7,12-17H2,1H3,(H,25,29) BGUBFYAMSVDVFX-UHFFFAOYSA-N 50051255 CHEMBL539740::N-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2-methylamino-benzamide; hydrochloride D(2) dopamine receptor Rattus norvegicus 4.7 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051255&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10622209 103948253 CHEMBL539740 ZINC03796428 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779493 Nc1cc(ccc1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12)C(F)(F)F InChI=1S/C23H26F3N5OS/c24-23(25,26)16-7-8-17(19(27)15-16)22(32)28-9-3-4-10-30-11-13-31(14-12-30)21-18-5-1-2-6-20(18)33-29-21/h1-2,5-8,15H,3-4,9-14,27H2,(H,28,32) UXBKOBHMEXWBKP-UHFFFAOYSA-N 50051260 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4-trifluoromethyl-benzamide; hydrochloride::CHEMBL537700 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051260&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10648292 103948258 CHEMBL537700 ZINC13747175 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779506 Nc1ccc(cc1)C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H27N5OS/c23-18-9-7-17(8-10-18)22(28)24-11-3-4-12-26-13-15-27(16-14-26)21-19-5-1-2-6-20(19)29-25-21/h1-2,5-10H,3-4,11-16,23H2,(H,24,28) JIHRPRDNQMLORX-UHFFFAOYSA-N 50051268 4-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-benzamide; hydrochloride::CHEMBL541782 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051268&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10549485 103948266 CHEMBL541782 ZINC13747141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50779507 Nc1cccc(F)c1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C22H26FN5OS/c23-17-7-5-8-18(24)20(17)22(29)25-10-3-4-11-27-12-14-28(15-13-27)21-16-6-1-2-9-19(16)30-26-21/h1-2,5-9H,3-4,10-15,24H2,(H,25,29) RCTGBBUBVFVGNR-UHFFFAOYSA-N 50051263 2-Amino-N-[4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-6-fluoro-benzamide; hydrochloride::CHEMBL537713 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1021/jm950551d 10.7270/Q2SQ912Q 8676355 Norman, MH; Rigdon, GC; Hall, WR; Navas, F Glaxo Wellcome Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50051263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50051263&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10622408 103948261 CHEMBL537713 ZINC13747182 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50800049 Oc1ccc(cc1)C1(O)CCN(CCCCc2ccccc2)CC1 InChI=1S/C21H27NO2/c23-20-11-9-19(10-12-20)21(24)13-16-22(17-14-21)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,23-24H,4-5,8,13-17H2 GWFIUFJXZVTKCH-UHFFFAOYSA-N 50085922 4-(4-Hydroxy-phenyl)-1-(4-phenyl-butyl)-piperidin-4-ol::CHEMBL174632 D(2) dopamine receptor Rattus norvegicus 22000 ChEMBL 10.1021/jm990428c 10.7270/Q20G3KVT 10715162 Guzikowski, AP; Tamiz, AP; Acosta-Burruel, M; Hong-Bae, S; Cai, SX; Hawkinson, JE; Keana, JF; Kesten, SR; Shipp, CT; Tran, M; Whittemore, ER; Woodward, RM; Wright, JL; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085922&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10592168 103985332 CHEMBL174632 ZINC13805763 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50800057 OC(CCc1ccccc1)CN1CCC(CC1)c1ccc(O)cc1 InChI=1S/C21H27NO2/c23-20-10-7-18(8-11-20)19-12-14-22(15-13-19)16-21(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,19,21,23-24H,6,9,12-16H2 XLCDZDPSIMQWPV-UHFFFAOYSA-N 50085927 4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-phenol::CHEMBL177620 D(2) dopamine receptor Rattus norvegicus 5900 ChEMBL 10.1021/jm990428c 10.7270/Q20G3KVT 10715162 Guzikowski, AP; Tamiz, AP; Acosta-Burruel, M; Hong-Bae, S; Cai, SX; Hawkinson, JE; Keana, JF; Kesten, SR; Shipp, CT; Tran, M; Whittemore, ER; Woodward, RM; Wright, JL; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085927&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10406322 103985337 CHEMBL177620 ZINC13805772 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50800060 OC(CCc1ccccc1)CN1CCC(O)(CC1)c1ccc(O)cc1 InChI=1S/C21H27NO3/c23-19-10-7-18(8-11-19)21(25)12-14-22(15-13-21)16-20(24)9-6-17-4-2-1-3-5-17/h1-5,7-8,10-11,20,23-25H,6,9,12-16H2 XLDIBMOCFJDOAH-UHFFFAOYSA-N 50085929 4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-piperidin-4-ol::CHEMBL177624 D(2) dopamine receptor Rattus norvegicus 105000 ChEMBL 10.1021/jm990428c 10.7270/Q20G3KVT 10715162 Guzikowski, AP; Tamiz, AP; Acosta-Burruel, M; Hong-Bae, S; Cai, SX; Hawkinson, JE; Keana, JF; Kesten, SR; Shipp, CT; Tran, M; Whittemore, ER; Woodward, RM; Wright, JL; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085929&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10759662 103985339 CHEMBL177624 ZINC13805777 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50795795 CCCN1CCO[C@H]2[C@@H]1CSc1ccc(O)cc21 InChI=1S/C14H19NO2S/c1-2-5-15-6-7-17-14-11-8-10(16)3-4-13(11)18-9-12(14)15/h3-4,8,12,14,16H,2,5-7,9H2,1H3/t12-,14+/m0/s1 OMQYELRKBALQJF-GXTWGEPZSA-N 50090832 (cis)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-thia-1-aza-phenanthren-6-ol::CHEMBL98836 D(2) dopamine receptor Rattus norvegicus 122 ChEMBL 10.1021/jm0000113 10.7270/Q2X067R1 10956195 van Vliet, LA; Rodenhuis, N; Dijkstra, D; Wikstrom, H; Pugsley, TA; Serpa, KA; Meltzer, LT; Heffner, TG; Wise, LD; Lajiness, ME; Huff, RM; Svensson, K; Sundell, S; Lundmark, M University Centre for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090832&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10515841 103989293 CHEMBL98836 ZINC13809437 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50795801 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm0000113 10.7270/Q2X067R1 10956195 van Vliet, LA; Rodenhuis, N; Dijkstra, D; Wikstrom, H; Pugsley, TA; Serpa, KA; Meltzer, LT; Heffner, TG; Wise, LD; Lajiness, ME; Huff, RM; Svensson, K; Sundell, S; Lundmark, M University Centre for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50795802 CCCN1CCO[C@H]2[C@H]1CSc1ccc(O)cc21 InChI=1S/C14H19NO2S/c1-2-5-15-6-7-17-14-11-8-10(16)3-4-13(11)18-9-12(14)15/h3-4,8,12,14,16H,2,5-7,9H2,1H3/t12-,14-/m1/s1 OMQYELRKBALQJF-TZMCWYRMSA-N 50090828 (-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4-oxa-9-thia-1-aza-phenanthren-6-ol::CHEMBL98305 D(2) dopamine receptor Rattus norvegicus 0.013000 ChEMBL 10.1021/jm0000113 10.7270/Q2X067R1 10956195 van Vliet, LA; Rodenhuis, N; Dijkstra, D; Wikstrom, H; Pugsley, TA; Serpa, KA; Meltzer, LT; Heffner, TG; Wise, LD; Lajiness, ME; Huff, RM; Svensson, K; Sundell, S; Lundmark, M University Centre for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50090828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50090828&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015731 103989289 CHEMBL98305 ZINC13809439 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50795818 CCCN1CCO[C@H]2[C@H]1COc1ccc(O)cc21 InChI=1S/C14H19NO3/c1-2-5-15-6-7-17-14-11-8-10(16)3-4-13(11)18-9-12(14)15/h3-4,8,12,14,16H,2,5-7,9H2,1H3/t12-,14-/m1/s1 YOILXOMTHPUMRG-TZMCWYRMSA-N 50010586 (+)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(4aR,10aR)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(Racemic)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(trans)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol (PD 128907)::1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::CHEMBL70565::PD 128,907 D(2) dopamine receptor Rattus norvegicus 5.7 ChEMBL 10.1021/jm0000113 10.7270/Q2X067R1 10956195 van Vliet, LA; Rodenhuis, N; Dijkstra, D; Wikstrom, H; Pugsley, TA; Serpa, KA; Meltzer, LT; Heffner, TG; Wise, LD; Lajiness, ME; Huff, RM; Svensson, K; Sundell, S; Lundmark, M University Centre for Pharmacy http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6O 7CMV 5311346 103923362 CHEMBL70565 ZINC25726114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50800084 Oc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1 InChI=1S/C21H27NO/c23-21-11-9-19(10-12-21)20-13-16-22(17-14-20)15-5-4-8-18-6-2-1-3-7-18/h1-3,6-7,9-12,20,23H,4-5,8,13-17H2 DFOMDPKHTWXUPV-UHFFFAOYSA-N 50369791 CHEMBL1202296 D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1021/jm990428c 10.7270/Q20G3KVT 10715162 Guzikowski, AP; Tamiz, AP; Acosta-Burruel, M; Hong-Bae, S; Cai, SX; Hawkinson, JE; Keana, JF; Kesten, SR; Shipp, CT; Tran, M; Whittemore, ER; Woodward, RM; Wright, JL; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9818121 160848893 CHEMBL1202296 ZINC03952636 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50800086 COc1ccc(cc1)C1CCN(CCCCc2ccccc2)CC1 InChI=1S/C22H29NO/c1-24-22-12-10-20(11-13-22)21-14-17-23(18-15-21)16-6-5-9-19-7-3-2-4-8-19/h2-4,7-8,10-13,21H,5-6,9,14-18H2,1H3 XVLSABBWYSMZKY-UHFFFAOYSA-N 50369789 CHEMBL1203894 D(2) dopamine receptor Rattus norvegicus 410 ChEMBL 10.1021/jm990428c 10.7270/Q20G3KVT 10715162 Guzikowski, AP; Tamiz, AP; Acosta-Burruel, M; Hong-Bae, S; Cai, SX; Hawkinson, JE; Keana, JF; Kesten, SR; Shipp, CT; Tran, M; Whittemore, ER; Woodward, RM; Wright, JL; Zhou, ZL CoCensys Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50369789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50369789&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9883688 160848891 CHEMBL1203894 ZINC13805750 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793418 COc1cccc(CCN2CCOCC2)c1OCCc1ccccc1 InChI=1S/C21H27NO3/c1-23-20-9-5-8-19(10-12-22-13-16-24-17-14-22)21(20)25-15-11-18-6-3-2-4-7-18/h2-9H,10-17H2,1H3 FTVYEECNDZRWTK-UHFFFAOYSA-N 50074829 4-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-morpholine; compound with oxalic acid::CHEMBL11669 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074829&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10497432 103968021 CHEMBL11669 ZINC13795773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793420 CCCCCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C26H39NO2/c1-4-6-7-11-19-27(18-5-2)20-16-24-14-15-25(28-3)26(22-24)29-21-17-23-12-9-8-10-13-23/h8-10,12-15,22H,4-7,11,16-21H2,1-3H3 FKJWRLPGIKDCNY-UHFFFAOYSA-N 50074827 CHEMBL542298::Hexyl-[2-(4-methoxy-3-phenethyloxy-phenyl)-ethyl]-propyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus 619 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074827&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10834641 103968019 CHEMBL542298 ZINC13795855 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793422 CCCN(CCC)CCc1cc(F)ccc1OCCc1ccccc1 InChI=1S/C22H30FNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3 QXLDCFDJKDJZRT-UHFFFAOYSA-N 50074831 CHEMBL543015::[2-(5-Fluoro-2-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074831&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10854876 103968023 CHEMBL543015 ZINC13795742 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793424 COc1ccc(CCN)cc1OCCc1ccccc1 InChI=1S/C17H21NO2/c1-19-16-8-7-15(9-11-18)13-17(16)20-12-10-14-5-3-2-4-6-14/h2-8,13H,9-12,18H2,1H3 PHZKTCBQEYKDQX-UHFFFAOYSA-N 50074833 2-(4-Methoxy-3-phenethyloxy-phenyl)-ethylamine; hydrochloride::CHEMBL542784 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074833&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10683536 103968025 CHEMBL542784 ZINC11860194 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793425 CCCN(CCC)CCc1cccc(OC)c1OCCCc1ccccc1 InChI=1S/C24H35NO2/c1-4-17-25(18-5-2)19-16-22-14-9-15-23(26-3)24(22)27-20-10-13-21-11-7-6-8-12-21/h6-9,11-12,14-15H,4-5,10,13,16-20H2,1-3H3 WYSXZUJEDLDTOM-UHFFFAOYSA-N 50074828 CHEMBL11290::{2-[3-Methoxy-2-(3-phenyl-propoxy)-phenyl]-ethyl}-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074828&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10666809 103968020 CHEMBL11290 ZINC13795844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793427 CCCN(CCC)CCc1ccc(OCCc2ccccc2)c(O)c1 InChI=1S/C22H31NO2/c1-3-14-23(15-4-2)16-12-20-10-11-22(21(24)18-20)25-17-13-19-8-6-5-7-9-19/h5-11,18,24H,3-4,12-17H2,1-2H3 MEPUUYBGUVQDIP-UHFFFAOYSA-N 50074835 5-(2-Dipropylamino-ethyl)-2-phenethyloxy-phenol; hydrochloride::CHEMBL542046 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10688630 103968027 CHEMBL542046 ZINC13795824 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793428 CCCN(CCC)CCc1cc(Cl)cc(Cl)c1OCCc1ccccc1 InChI=1S/C22H29Cl2NO/c1-3-12-25(13-4-2)14-10-19-16-20(23)17-21(24)22(19)26-15-11-18-8-6-5-7-9-18/h5-9,16-17H,3-4,10-15H2,1-2H3 OUPQTYHOIFANCC-UHFFFAOYSA-N 50074834 CHEMBL11637::[2-(3,5-Dichloro-2-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074834&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10739385 103968026 CHEMBL11637 ZINC13795751 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808456 C(N1CCN(Cc2ccccc2)CC1)c1cn(c(n1)-c1ccccc1)-c1ccccc1 InChI=1S/C27H28N4/c1-4-10-23(11-5-1)20-29-16-18-30(19-17-29)21-25-22-31(26-14-8-3-9-15-26)27(28-25)24-12-6-2-7-13-24/h1-15,22H,16-21H2 ZVSYVUQYFJBBHB-UHFFFAOYSA-N 50119465 1-Benzyl-4-(1,2-diphenyl-1H-imidazol-4-ylmethyl)-piperazine::CHEMBL356116 D(2) dopamine receptor Rattus norvegicus 4908 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10862446 104012678 CHEMBL356116 ZINC22927693 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808463 CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C28H30N4O/c1-2-33-27-16-10-9-15-26(27)31-19-17-30(18-20-31)21-24-22-32(25-13-7-4-8-14-25)28(29-24)23-11-5-3-6-12-23/h3-16,22H,2,17-21H2,1H3 VVYABMSSBXSXFF-UHFFFAOYSA-N 50119469 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(2-ethoxy-phenyl)-piperazine::CHEMBL143744 D(2) dopamine receptor Rattus norvegicus 34.7 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119469&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11059222 104012682 CHEMBL143744 ZINC13491649 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808467 Fc1ccc(cc1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C26H25FN4/c27-22-11-13-24(14-12-22)30-17-15-29(16-18-30)19-23-20-31(25-9-5-2-6-10-25)26(28-23)21-7-3-1-4-8-21/h1-14,20H,15-19H2 YUQFGZOLGFQMFU-UHFFFAOYSA-N 50119466 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(4-fluoro-phenyl)-piperazine::CHEMBL141077 D(2) dopamine receptor Rattus norvegicus 1285.5 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10993325 104012679 CHEMBL141077 ZINC13491643 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808474 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 3.4 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808477 C(N1CCN(CC1)c1ccccc1)c1cn(c(n1)-c1ccccc1)-c1ccccc1 InChI=1S/C26H26N4/c1-4-10-22(11-5-1)26-27-23(21-30(26)25-14-8-3-9-15-25)20-28-16-18-29(19-17-28)24-12-6-2-7-13-24/h1-15,21H,16-20H2 RULCKCZJCPRPHI-UHFFFAOYSA-N 50119475 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-phenyl-piperazine::CHEMBL142309 D(2) dopamine receptor Rattus norvegicus 1017 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119475&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11003766 104012688 CHEMBL142309 ZINC13491635 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808479 CN1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C21H24N4/c1-23-12-14-24(15-13-23)16-19-17-25(20-10-6-3-7-11-20)21(22-19)18-8-4-2-5-9-18/h2-11,17H,12-16H2,1H3 HQPLZLFCIJHWSF-UHFFFAOYSA-N 50119474 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-methyl-piperazine::CHEMBL344995 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10892936 104012687 CHEMBL344995 ZINC22927697 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808483 C(N1CCN(CC1)c1ccccn1)c1cn(c(n1)-c1ccccc1)-c1ccccc1 InChI=1S/C25H25N5/c1-3-9-21(10-4-1)25-27-22(20-30(25)23-11-5-2-6-12-23)19-28-15-17-29(18-16-28)24-13-7-8-14-26-24/h1-14,20H,15-19H2 YATVHWPPUPOJPS-UHFFFAOYSA-N 50119468 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-pyridin-2-yl-piperazine::CHEMBL344796 D(2) dopamine receptor Rattus norvegicus 2744 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11143739 104012681 CHEMBL344796 ZINC13491646 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808484 FC(F)(F)c1cccc(c1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C27H25F3N4/c28-27(29,30)22-10-7-13-25(18-22)33-16-14-32(15-17-33)19-23-20-34(24-11-5-2-6-12-24)26(31-23)21-8-3-1-4-9-21/h1-13,18,20H,14-17,19H2 SGAILRJJEWIMSO-UHFFFAOYSA-N 50119478 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(3-trifluoromethyl-phenyl)-piperazine::CHEMBL342119 D(2) dopamine receptor Rattus norvegicus 135.5 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119478&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11123429 104012691 CHEMBL342119 ZINC13491644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808489 Clc1cccc(c1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C26H25ClN4/c27-22-10-7-13-25(18-22)30-16-14-29(15-17-30)19-23-20-31(24-11-5-2-6-12-24)26(28-23)21-8-3-1-4-9-21/h1-13,18,20H,14-17,19H2 FISSWGCIUFVFKT-UHFFFAOYSA-N 50119473 1-(3-Chloro-phenyl)-4-(1,2-diphenyl-1H-imidazol-4-ylmethyl)-piperazine::CHEMBL141824 D(2) dopamine receptor Rattus norvegicus 2135.5 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11069992 104012686 CHEMBL141824 ZINC13491640 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808490 Fc1ccc(cc1)-c1nc(CN2CCN(CC2)c2ccccc2)cn1-c1ccc(F)cc1 InChI=1S/C26H24F2N4/c27-21-8-6-20(7-9-21)26-29-23(19-32(26)25-12-10-22(28)11-13-25)18-30-14-16-31(17-15-30)24-4-2-1-3-5-24/h1-13,19H,14-18H2 OCPUMUSLGLBFKT-UHFFFAOYSA-N 50119479 1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethyl]-4-phenyl-piperazine::CHEMBL143218 D(2) dopamine receptor Rattus norvegicus 167.2 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10862911 104012692 CHEMBL143218 ZINC13491650 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808492 CCOc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccc(F)cc2)-c2ccc(F)cc2)CC1 InChI=1S/C28H28F2N4O/c1-2-35-27-6-4-3-5-26(27)33-17-15-32(16-18-33)19-24-20-34(25-13-11-23(30)12-14-25)28(31-24)21-7-9-22(29)10-8-21/h3-14,20H,2,15-19H2,1H3 OUQCDNRPXRIJIM-UHFFFAOYSA-N 50119471 1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethyl]-4-(2-ethoxy-phenyl)-piperazine::CHEMBL142147 D(2) dopamine receptor Rattus norvegicus 267.5 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11049024 104012684 CHEMBL142147 ZINC13491652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808494 FC(F)(F)c1ccc(cc1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C27H25F3N4/c28-27(29,30)22-11-13-24(14-12-22)33-17-15-32(16-18-33)19-23-20-34(25-9-5-2-6-10-25)26(31-23)21-7-3-1-4-8-21/h1-14,20H,15-19H2 PEIQSKJNCYGQQW-UHFFFAOYSA-N 50119477 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(4-trifluoromethyl-phenyl)-piperazine::CHEMBL142825 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119477&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11026953 104012690 CHEMBL142825 ZINC13491645 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793430 CCCN(CCC)CCc1ccccc1OCCc1ccccc1 InChI=1S/C22H31NO/c1-3-16-23(17-4-2)18-14-21-12-8-9-13-22(21)24-19-15-20-10-6-5-7-11-20/h5-13H,3-4,14-19H2,1-2H3 GCZNMJYMLHINBH-UHFFFAOYSA-N 50074838 CHEMBL276007::[2-(2-Phenethyloxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus 436 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074838&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10806006 103968030 CHEMBL276007 ZINC13795757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793432 COc1cccc(CCN2CCCC2)c1OCCc1ccccc1 InChI=1S/C21H27NO2/c1-23-20-11-7-10-19(12-16-22-14-5-6-15-22)21(20)24-17-13-18-8-3-2-4-9-18/h2-4,7-11H,5-6,12-17H2,1H3 XCBHCSGECGOBJS-UHFFFAOYSA-N 50074843 1-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-pyrrolidine; compound with oxalic acid::CHEMBL11479 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074843&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10734857 103968035 CHEMBL11479 ZINC13795765 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793434 CCCN(CCC)CCc1ccc(OCCc2ccccc2)cc1OC InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(19-23(21)25-3)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3 VOGHRFUPPGCETI-UHFFFAOYSA-N 50074840 CHEMBL11474::[2-(2-Methoxy-4-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074840&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11792545 103968032 CHEMBL11474 ZINC13795733 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793435 COc1cccc(CCN2CCN(CC2)c2ccccc2)c1OCCc1ccccc1 InChI=1S/C27H32N2O2/c1-30-26-14-8-11-24(27(26)31-22-16-23-9-4-2-5-10-23)15-17-28-18-20-29(21-19-28)25-12-6-3-7-13-25/h2-14H,15-22H2,1H3 DWIWEXXTWKPVSB-UHFFFAOYSA-N 50074841 1-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-4-phenyl-piperazine; compound with oxalic acid::CHEMBL416335 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074841&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10669610 103968033 CHEMBL416335 ZINC13795779 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793436 CCCN(CCC)CCc1cccc(F)c1OCCc1ccccc1 InChI=1S/C22H30FNO/c1-3-15-24(16-4-2)17-13-20-11-8-12-21(23)22(20)25-18-14-19-9-6-5-7-10-19/h5-12H,3-4,13-18H2,1-2H3 VEHFIFIDIKSWFI-UHFFFAOYSA-N 50074842 CHEMBL11535::[2-(3-Fluoro-2-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074842&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10641133 103968034 CHEMBL11535 ZINC13795739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793437 CCCN(CCC)CCc1cc(Br)ccc1OCCc1ccccc1 InChI=1S/C22H30BrNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3 SHQDABGNGKOVJS-UHFFFAOYSA-N 50074844 CHEMBL11279::[2-(5-Bromo-2-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus 169 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074844&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10739961 103968036 CHEMBL11279 ZINC13795748 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793444 CCCN(CCC)CCc1ccc(OC)c(OCc2ccccc2)c1 InChI=1S/C22H31NO2/c1-4-14-23(15-5-2)16-13-19-11-12-21(24-3)22(17-19)25-18-20-9-7-6-8-10-20/h6-12,17H,4-5,13-16,18H2,1-3H3 LGELOJMMHDCOSZ-UHFFFAOYSA-N 50074852 CHEMBL11598::[2-(3-Benzyloxy-4-methoxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10545204 103968044 CHEMBL11598 ZINC13795720 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793446 CCCN(CCC)CCc1cccc(OC)c1OCCc1ccccc1 InChI=1S/C23H33NO2/c1-4-16-24(17-5-2)18-14-21-12-9-13-22(25-3)23(21)26-19-15-20-10-7-6-8-11-20/h6-13H,4-5,14-19H2,1-3H3 WICNRYBJDUQEBR-UHFFFAOYSA-N 50074839 CHEMBL542047::[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074839&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10832067 103968031 CHEMBL542047 ZINC13795725 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793448 CCCN(CCC)CCc1ccc(Cl)cc1OCCc1ccccc1 InChI=1S/C22H30ClNO/c1-3-14-24(15-4-2)16-12-20-10-11-21(23)18-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3 NTRDLGCZJKGEAG-UHFFFAOYSA-N 50074851 CHEMBL542048::[2-(4-Chloro-2-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10760963 103968043 CHEMBL542048 ZINC13795745 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793450 CCCN(CCCO)CCc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C23H33NO3/c1-3-14-24(15-7-17-25)16-12-21-10-11-22(26-2)23(19-21)27-18-13-20-8-5-4-6-9-20/h4-6,8-11,19,25H,3,7,12-18H2,1-2H3 WDJQJNKOSAYQGG-UHFFFAOYSA-N 50074854 3-{[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-propyl-amino}-propan-1-ol; hydrochloride::CHEMBL542783 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10690621 103968046 CHEMBL542783 ZINC13795858 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793455 CCCNCCc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C20H27NO2/c1-3-13-21-14-11-18-9-10-19(22-2)20(16-18)23-15-12-17-7-5-4-6-8-17/h4-10,16,21H,3,11-15H2,1-2H3 AEQMNSOSQSZZIB-UHFFFAOYSA-N 50074857 CHEMBL542786::[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-propyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10710332 103968049 CHEMBL542786 ZINC13795850 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793456 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 5.1 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793458 CCCN(CCC)CCc1cc(Cl)ccc1OCCc1ccccc1 InChI=1S/C22H30ClNO/c1-3-14-24(15-4-2)16-12-20-18-21(23)10-11-22(20)25-17-13-19-8-6-5-7-9-19/h5-11,18H,3-4,12-17H2,1-2H3 FLEVBJUHJCFHCI-UHFFFAOYSA-N 50074850 CHEMBL11803::[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus 112 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074850&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10689843 103968042 CHEMBL11803 ZINC13795827 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793459 CCCN(CCC)CCc1cc(Cl)ccc1OCc1ccccc1 InChI=1S/C21H28ClNO/c1-3-13-23(14-4-2)15-12-19-16-20(22)10-11-21(19)24-17-18-8-6-5-7-9-18/h5-11,16H,3-4,12-15,17H2,1-2H3 CEKIPZCJZKWYBV-UHFFFAOYSA-N 50074858 CHEMBL11675::[2-(2-Benzyloxy-5-chloro-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus 337 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10569564 103968050 CHEMBL11675 ZINC13795723 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793460 CCCN(CCC)CCc1ccc(OC)c(OCCc2cccc(Cl)c2)c1 InChI=1S/C23H32ClNO2/c1-4-13-25(14-5-2)15-11-20-9-10-22(26-3)23(18-20)27-16-12-19-7-6-8-21(24)17-19/h6-10,17-18H,4-5,11-16H2,1-3H3 RWNSMZMJYLDHGA-UHFFFAOYSA-N 50074859 (2-{3-[2-(3-Chloro-phenyl)-ethoxy]-4-methoxy-phenyl}-ethyl)-dipropyl-amine; compound with oxalic acid::CHEMBL12107 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10786587 103968051 CHEMBL12107 ZINC13795833 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793462 CCCN(CCC)CCc1cc(Br)ccc1OCCCc1ccccc1 InChI=1S/C23H32BrNO/c1-3-15-25(16-4-2)17-14-21-19-22(24)12-13-23(21)26-18-8-11-20-9-6-5-7-10-20/h5-7,9-10,12-13,19H,3-4,8,11,14-18H2,1-2H3 BSDLWPJRXGTLSE-UHFFFAOYSA-N 50074860 CHEMBL11231::{2-[5-Bromo-2-(3-phenyl-propoxy)-phenyl]-ethyl}-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus 685 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074860&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574029 103968052 CHEMBL11231 ZINC13795759 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793464 Clc1ccc(OCCc2ccccc2)c(CCN2CCCC2)c1 InChI=1S/C20H24ClNO/c21-19-8-9-20(23-15-11-17-6-2-1-3-7-17)18(16-19)10-14-22-12-4-5-13-22/h1-3,6-9,16H,4-5,10-15H2 GAQYIAUCJFSION-UHFFFAOYSA-N 50074863 1-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-pyrrolidine; compound with oxalic acid::CHEMBL11255 D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10496628 103968055 CHEMBL11255 ZINC13795771 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793465 CCCN(CCC)CCc1ccc(OC)c(OCCc2ccc(F)cc2)c1 InChI=1S/C23H32FNO2/c1-4-14-25(15-5-2)16-12-20-8-11-22(26-3)23(18-20)27-17-13-19-6-9-21(24)10-7-19/h6-11,18H,4-5,12-17H2,1-3H3 ANUUPTYCGZUUQS-UHFFFAOYSA-N 50074866 (2-{3-[2-(4-Fluoro-phenyl)-ethoxy]-4-methoxy-phenyl}-ethyl)-dipropyl-amine; hydrochloride::CHEMBL537238 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9951448 103968058 CHEMBL537238 ZINC13795830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793467 Clc1ccc(OCCc2ccccc2)c(CCN2CCN(CC2)c2ccccn2)c1 InChI=1S/C25H28ClN3O/c26-23-9-10-24(30-19-12-21-6-2-1-3-7-21)22(20-23)11-14-28-15-17-29(18-16-28)25-8-4-5-13-27-25/h1-10,13,20H,11-12,14-19H2 QNGUJVXVKSDPRH-UHFFFAOYSA-N 50074868 1-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-4-pyridin-2-yl-piperazine; compound with oxalic acid::CHEMBL416521 D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074868&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10717092 103968060 CHEMBL416521 ZINC13795869 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793468 Clc1ccc(OCCc2ccccc2)c(CCCN2CCN(CC2)c2ccccc2)c1 InChI=1S/C27H31ClN2O/c28-25-13-14-27(31-21-15-23-8-3-1-4-9-23)24(22-25)10-7-16-29-17-19-30(20-18-29)26-11-5-2-6-12-26/h1-6,8-9,11-14,22H,7,10,15-21H2 YWMWWYCRLCCWMQ-UHFFFAOYSA-N 50074861 1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-phenyl-piperazine; compound with oxalic acid::CHEMBL11437 D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10526856 103968053 CHEMBL11437 ZINC13795803 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793469 CCCN(CCC)CCc1ccc(OC)c(OCCc2ccc(OC)cc2)c1 InChI=1S/C24H35NO3/c1-5-15-25(16-6-2)17-13-21-9-12-23(27-4)24(19-21)28-18-14-20-7-10-22(26-3)11-8-20/h7-12,19H,5-6,13-18H2,1-4H3 FNUKXDJBENZKIF-UHFFFAOYSA-N 50074867 (2-{4-Methoxy-3-[2-(4-methoxy-phenyl)-ethoxy]-phenyl}-ethyl)-dipropyl-amine; compound with oxalic acid::CHEMBL11736 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10572164 103968059 CHEMBL11736 ZINC13795836 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793471 CCCN(CCC(C)C)CCc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C25H37NO2/c1-5-16-26(17-13-21(2)3)18-14-23-11-12-24(27-4)25(20-23)28-19-15-22-9-7-6-8-10-22/h6-12,20-21H,5,13-19H2,1-4H3 NLNGQVGDYQXMEI-UHFFFAOYSA-N 50074865 CHEMBL542295::[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-(3-methyl-butyl)-propyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus 680 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074865&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10596150 103968057 CHEMBL542295 ZINC13795853 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793474 CCCN(CCC)CCc1cc(Cl)ccc1OCCCc1ccccc1 InChI=1S/C23H32ClNO/c1-3-15-25(16-4-2)17-14-21-19-22(24)12-13-23(21)26-18-8-11-20-9-6-5-7-10-20/h5-7,9-10,12-13,19H,3-4,8,11,14-18H2,1-2H3 MXRVXVJIPWKDEB-UHFFFAOYSA-N 50074849 CHEMBL11740::{2-[5-Chloro-2-(3-phenyl-propoxy)-phenyl]-ethyl}-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus 876 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074849&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10523418 103968041 CHEMBL11740 ZINC13795762 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793475 COc1ccc(CCN2CCCC2)cc1OCCc1ccccc1 InChI=1S/C21H27NO2/c1-23-20-10-9-19(11-15-22-13-5-6-14-22)17-21(20)24-16-12-18-7-3-2-4-8-18/h2-4,7-10,17H,5-6,11-16H2,1H3 AFGQADKELTYBPU-UHFFFAOYSA-N 50074855 1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-pyrrolidine; compound with oxalic acid::CHEMBL11311 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10496297 103968047 CHEMBL11311 ZINC13795768 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793478 CCCN(CCC)CCc1ccc(O)c2OCc3ccccc3-c12 InChI=1S/C21H27NO2/c1-3-12-22(13-4-2)14-11-16-9-10-19(23)21-20(16)18-8-6-5-7-17(18)15-24-21/h5-10,23H,3-4,11-15H2,1-2H3 HLHQKXNSWGPQAK-UHFFFAOYSA-N 50074845 1-(2-Dipropylamino-ethyl)-6H-benzo[c]chromen-4-ol; hydrochloride::CHEMBL557589 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074845&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10496298 103968037 CHEMBL557589 ZINC13795864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793479 Clc1ccc(OCCc2ccccc2)c(CCN2CCN(CC2)c2ncccn2)c1 InChI=1S/C24H27ClN4O/c25-22-7-8-23(30-18-10-20-5-2-1-3-6-20)21(19-22)9-13-28-14-16-29(17-15-28)24-26-11-4-12-27-24/h1-8,11-12,19H,9-10,13-18H2 PVWHKQCDSLCNIO-UHFFFAOYSA-N 50074870 2-{4-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-piperazin-1-yl}-pyrimidine; compound with oxalic acid::CHEMBL11352 D(2) dopamine receptor Rattus norvegicus 143 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10574272 103968062 CHEMBL11352 ZINC13795872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793481 COc1ccc(CCN2CCN(CC2)c2ccccc2OC)cc1OCCc1ccccc1 InChI=1S/C28H34N2O3/c1-31-26-11-7-6-10-25(26)30-19-17-29(18-20-30)16-14-24-12-13-27(32-2)28(22-24)33-21-15-23-8-4-3-5-9-23/h3-13,22H,14-21H2,1-2H3 VMYVUXDFCVFDSX-UHFFFAOYSA-N 50074872 1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL545598 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10599509 103968064 CHEMBL545598 ZINC13795788 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793489 CCCN(CCC)CCc1ccc(OC)c2OCc3ccccc3-c12 InChI=1S/C22H29NO2/c1-4-13-23(14-5-2)15-12-17-10-11-20(24-3)22-21(17)19-9-7-6-8-18(19)16-25-22/h6-11H,4-5,12-16H2,1-3H3 NCEJLSYQJKEFOY-UHFFFAOYSA-N 50074825 CHEMBL554037::[2-(4-Methoxy-6H-benzo[c]chromen-1-yl)-ethyl]-dipropyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074825&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10712141 103968017 CHEMBL554037 ZINC13795861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793490 CCCN(CCC)CCCCc1cc(Cl)ccc1OCCc1ccccc1 InChI=1S/C24H34ClNO/c1-3-16-26(17-4-2)18-9-8-12-22-20-23(25)13-14-24(22)27-19-15-21-10-6-5-7-11-21/h5-7,10-11,13-14,20H,3-4,8-9,12,15-19H2,1-2H3 PEAGLIDHYNXBNE-UHFFFAOYSA-N 50074875 CHEMBL11657::[4-(5-Chloro-2-phenethyloxy-phenyl)-butyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074875&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10596406 103968067 CHEMBL11657 ZINC13795819 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793491 COc1ccccc1N1CCN(CCc2cc(Cl)ccc2OCCc2ccccc2)CC1 InChI=1S/C27H31ClN2O2/c1-31-27-10-6-5-9-25(27)30-18-16-29(17-19-30)15-13-23-21-24(28)11-12-26(23)32-20-14-22-7-3-2-4-8-22/h2-12,21H,13-20H2,1H3 ARATVKMWZQJWME-UHFFFAOYSA-N 50074836 1-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL542542 D(2) dopamine receptor Rattus norvegicus 88 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074836&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10694873 103968028 CHEMBL542542 ZINC13795791 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793493 Clc1ccc(OCCc2ccccc2)c(CCN2CCOCC2)c1 InChI=1S/C20H24ClNO2/c21-19-6-7-20(24-13-9-17-4-2-1-3-5-17)18(16-19)8-10-22-11-14-23-15-12-22/h1-7,16H,8-15H2 ICIMYSGOYSELPS-UHFFFAOYSA-N 50074874 4-[2-(5-Chloro-2-phenethyloxy-phenyl)-ethyl]-morpholine; compound with oxalic acid::CHEMBL11289 D(2) dopamine receptor Rattus norvegicus 163 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10783740 103968066 CHEMBL11289 ZINC13795776 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793494 COc1ccc(CCN2CCOCC2)cc1OCCc1ccccc1 InChI=1S/C21H27NO3/c1-23-20-8-7-19(9-11-22-12-15-24-16-13-22)17-21(20)25-14-10-18-5-3-2-4-6-18/h2-8,17H,9-16H2,1H3 BJYOTRPBJFDROL-UHFFFAOYSA-N 50074878 4-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-morpholine; compound with oxalic acid::CHEMBL11735 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074878&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10712276 103968070 CHEMBL11735 ZINC13795874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793496 CCCN(CCC)CCc1cc(Br)cc(Br)c1OCCc1ccccc1 InChI=1S/C22H29Br2NO/c1-3-12-25(13-4-2)14-10-19-16-20(23)17-21(24)22(19)26-15-11-18-8-6-5-7-9-18/h5-9,16-17H,3-4,10-15H2,1-2H3 TXETYTQTVHANFD-UHFFFAOYSA-N 50074847 CHEMBL11590::[2-(3,5-Dibromo-2-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074847&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10814672 103968039 CHEMBL11590 ZINC13795754 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808503 COc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C27H28N4O/c1-32-26-15-9-8-14-25(26)30-18-16-29(17-19-30)20-23-21-31(24-12-6-3-7-13-24)27(28-23)22-10-4-2-5-11-22/h2-15,21H,16-20H2,1H3 UMUCSJYFZZHPKI-UHFFFAOYSA-N 50119480 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(2-methoxy-phenyl)-piperazine::CHEMBL358316 D(2) dopamine receptor Rattus norvegicus 70.3 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119480&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025385 104012693 CHEMBL358316 ZINC13491636 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808504 COc1cccc(c1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C27H28N4O/c1-32-26-14-8-13-25(19-26)30-17-15-29(16-18-30)20-23-21-31(24-11-6-3-7-12-24)27(28-23)22-9-4-2-5-10-22/h2-14,19,21H,15-18,20H2,1H3 AZHSETOUVUIVCI-UHFFFAOYSA-N 50119464 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(3-methoxy-phenyl)-piperazine::CHEMBL344202 D(2) dopamine receptor Rattus norvegicus 167.5 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119464&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11112701 104012677 CHEMBL344202 ZINC13491637 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808505 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 17.5 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808508 Clc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C26H25ClN4/c27-24-13-7-8-14-25(24)30-17-15-29(16-18-30)19-22-20-31(23-11-5-2-6-12-23)26(28-22)21-9-3-1-4-10-21/h1-14,20H,15-19H2 ZOCYJFUKHOSYAG-UHFFFAOYSA-N 50119476 1-(2-Chloro-phenyl)-4-(1,2-diphenyl-1H-imidazol-4-ylmethyl)-piperazine::CHEMBL344084 D(2) dopamine receptor Rattus norvegicus 295.5 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119476&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11761776 104012689 CHEMBL344084 ZINC13491639 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808509 Clc1ccc(cc1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C26H25ClN4/c27-22-11-13-24(14-12-22)30-17-15-29(16-18-30)19-23-20-31(25-9-5-2-6-10-25)26(28-23)21-7-3-1-4-8-21/h1-14,20H,15-19H2 VVXPDQWPTOGEHG-UHFFFAOYSA-N 50119463 1-(4-Chloro-phenyl)-4-(1,2-diphenyl-1H-imidazol-4-ylmethyl)-piperazine::CHEMBL356068 D(2) dopamine receptor Rattus norvegicus 91.8 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119463&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11112784 104012676 CHEMBL356068 ZINC13491641 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808512 COc1ccc(cc1)N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C27H28N4O/c1-32-26-14-12-24(13-15-26)30-18-16-29(17-19-30)20-23-21-31(25-10-6-3-7-11-25)27(28-23)22-8-4-2-5-9-22/h2-15,21H,16-20H2,1H3 JFBBVXDQTARMEM-UHFFFAOYSA-N 50119467 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(4-methoxy-phenyl)-piperazine::CHEMBL341743 D(2) dopamine receptor Rattus norvegicus 5796 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11037296 104012680 CHEMBL341743 ZINC13491638 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808513 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 2108 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808514 COc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccc(F)cc2)-c2ccc(F)cc2)CC1 InChI=1S/C27H26F2N4O/c1-34-26-5-3-2-4-25(26)32-16-14-31(15-17-32)18-23-19-33(24-12-10-22(29)11-13-24)27(30-23)20-6-8-21(28)9-7-20/h2-13,19H,14-18H2,1H3 YKZBAGIEZBPODW-UHFFFAOYSA-N 50119472 1-[1,2-Bis-(4-fluoro-phenyl)-1H-imidazol-4-ylmethyl]-4-(2-methoxy-phenyl)-piperazine::CHEMBL143372 D(2) dopamine receptor Rattus norvegicus 120.2 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11059579 104012685 CHEMBL143372 ZINC13491651 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50808516 Fc1ccccc1N1CCN(Cc2cn(c(n2)-c2ccccc2)-c2ccccc2)CC1 InChI=1S/C26H25FN4/c27-24-13-7-8-14-25(24)30-17-15-29(16-18-30)19-22-20-31(23-11-5-2-6-12-23)26(28-22)21-9-3-1-4-10-21/h1-14,20H,15-19H2 NKRWGVAMPNUXFY-UHFFFAOYSA-N 50119470 1-(1,2-Diphenyl-1H-imidazol-4-ylmethyl)-4-(2-fluoro-phenyl)-piperazine::CHEMBL356993 D(2) dopamine receptor Rattus norvegicus 408.5 ChEMBL 10.1021/jm020848t 10.7270/Q21G0N0M 12361392 Asproni, B; Pau, A; Bitti, M; Melosu, M; Cerri, R; Dazzi, L; Seu, E; Maciocco, E; Sanna, E; Busonero, F; Talani, G; Pusceddu, L; Altomare, C; Trapani, G; Biggio, G Universit£ degli Studi di Sassari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10873343 104012683 CHEMBL356993 ZINC13491642 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793502 CCCN(CCC)CCc1ccc(OC)c(OCCc2cccs2)c1 InChI=1S/C21H31NO2S/c1-4-12-22(13-5-2)14-10-18-8-9-20(23-3)21(17-18)24-15-11-19-7-6-16-25-19/h6-9,16-17H,4-5,10-15H2,1-3H3 OLLZIXVTODGRHR-UHFFFAOYSA-N 50074873 CHEMBL542049::{2-[4-Methoxy-3-(2-thiophen-2-yl-ethoxy)-phenyl]-ethyl}-dipropyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074873&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10642354 103968065 CHEMBL542049 ZINC13795841 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793504 Clc1ccc(OCCc2ccccc2)c(CCCN2CCN(CC2)c2ncccn2)c1 InChI=1S/C25H29ClN4O/c26-23-9-10-24(31-19-11-21-6-2-1-3-7-21)22(20-23)8-4-14-29-15-17-30(18-16-29)25-27-12-5-13-28-25/h1-3,5-7,9-10,12-13,20H,4,8,11,14-19H2 OIVUHYORRWTYGO-UHFFFAOYSA-N 50074876 2-{4-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-piperazin-1-yl}-pyrimidine; compound with oxalic acid::CHEMBL11534 D(2) dopamine receptor Rattus norvegicus 115 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074876&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797218 103968068 CHEMBL11534 ZINC13795815 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793507 CCCN(CCC)CCCc1cccc(OC)c1OCCc1ccccc1 InChI=1S/C24H35NO2/c1-4-17-25(18-5-2)19-10-14-22-13-9-15-23(26-3)24(22)27-20-16-21-11-7-6-8-12-21/h6-9,11-13,15H,4-5,10,14,16-20H2,1-3H3 PAJNYZHSINMOLM-UHFFFAOYSA-N 50074879 CHEMBL275948::[3-(3-Methoxy-2-phenethyloxy-phenyl)-propyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074879&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10499353 103968071 CHEMBL275948 ZINC13795795 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793508 CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)23(19-21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3 YBLIQJGXRLZBCZ-UHFFFAOYSA-N 50170660 CHEMBL190883::CHEMBL521582::N,N-dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine::N-(4-methoxy-3-phenethoxyphenethyl)-N-propylpropan-1-amine::NE-100::[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-dipropyl-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170660&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GKY 6DK0 9841596 104057040 CHEMBL190883CHEMBL521582 6679 ZINC00598622 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793510 CCCN(CCC)CCCc1cc(Br)ccc1OCCc1ccccc1 InChI=1S/C23H32BrNO/c1-3-15-25(16-4-2)17-8-11-21-19-22(24)12-13-23(21)26-18-14-20-9-6-5-7-10-20/h5-7,9-10,12-13,19H,3-4,8,11,14-18H2,1-2H3 PEDAAYQDDCDPGB-UHFFFAOYSA-N 50074880 CHEMBL269638::[3-(5-Bromo-2-phenethyloxy-phenyl)-propyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus 438 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074880&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10716898 103968072 CHEMBL269638 ZINC13795800 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793511 CCCN(CCC)CCc1ccc(OCCc2ccccc2)c(OC)c1 InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(23(19-21)25-3)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3 NDQMIVFSBKTDEN-UHFFFAOYSA-N 50074830 CHEMBL11894::[2-(3-Methoxy-4-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074830&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10832068 103968022 CHEMBL11894 ZINC13795736 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793515 CCCN(CCC)CCc1ccc(OC)cc1OCCc1ccccc1 InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-11-12-22(25-3)19-23(21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3 MIDKBWYXSPDSHV-UHFFFAOYSA-N 50074826 CHEMBL11774::[2-(4-Methoxy-2-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074826&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10808129 103968018 CHEMBL11774 ZINC13795728 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793519 Clc1ccc(OCCc2ccccc2)c(CCCN2CCN(CC2)c2ccccn2)c1 InChI=1S/C26H30ClN3O/c27-24-11-12-25(31-20-13-22-7-2-1-3-8-22)23(21-24)9-6-15-29-16-18-30(19-17-29)26-10-4-5-14-28-26/h1-5,7-8,10-12,14,21H,6,9,13,15-20H2 ZVBDCXMMMNDDKQ-UHFFFAOYSA-N 50074837 1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-pyridin-2-yl-piperazine; compound with oxalic acid::CHEMBL11581 D(2) dopamine receptor Rattus norvegicus 93 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074837&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11797175 103968029 CHEMBL11581 ZINC13795809 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793520 CCCN(CCC)CCc1ccc(O)c(OCCc2ccccc2)c1 InChI=1S/C22H31NO2/c1-3-14-23(15-4-2)16-12-20-10-11-21(24)22(18-20)25-17-13-19-8-6-5-7-9-19/h5-11,18,24H,3-4,12-17H2,1-2H3 DMVMWWXQRZDRJE-UHFFFAOYSA-N 50074869 4-(2-Dipropylamino-ethyl)-2-phenethyloxy-phenol; hydrochloride::CHEMBL542785 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10688629 103968061 CHEMBL542785 ZINC13795822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793523 Cc1cccc(n1)N1CCN(CCCc2cc(Cl)ccc2OCCc2ccccc2)CC1 InChI=1S/C27H32ClN3O/c1-22-7-5-11-27(29-22)31-18-16-30(17-19-31)15-6-10-24-21-25(28)12-13-26(24)32-20-14-23-8-3-2-4-9-23/h2-5,7-9,11-13,21H,6,10,14-20H2,1H3 DXBQAQOOFQNNMF-UHFFFAOYSA-N 50074882 1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-(6-methyl-pyridin-2-yl)-piperazine; compound with oxalic acid::CHEMBL11161 D(2) dopamine receptor Rattus norvegicus 293 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074882&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10623414 103968074 CHEMBL11161 ZINC13795812 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793526 COc1ccccc1N1CCN(CCCc2cc(Cl)ccc2OCCc2ccccc2)CC1 InChI=1S/C28H33ClN2O2/c1-32-28-12-6-5-11-26(28)31-19-17-30(18-20-31)16-7-10-24-22-25(29)13-14-27(24)33-21-15-23-8-3-2-4-9-23/h2-6,8-9,11-14,22H,7,10,15-21H2,1H3 YUISEVXRRGOSEQ-UHFFFAOYSA-N 50074871 1-[3-(5-Chloro-2-phenethyloxy-phenyl)-propyl]-4-(2-methoxy-phenyl)-piperazine; compound with oxalic acid::CHEMBL11380 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10600238 103968063 CHEMBL11380 ZINC13795806 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793527 COc1cccc(CCN2CCN(CC2)c2ccccn2)c1OCCc1ccccc1 InChI=1S/C26H31N3O2/c1-30-24-11-7-10-23(26(24)31-21-14-22-8-3-2-4-9-22)13-16-28-17-19-29(20-18-28)25-12-5-6-15-27-25/h2-12,15H,13-14,16-21H2,1H3 MKQDBWIOXMWPGB-UHFFFAOYSA-N 50074862 1-[2-(3-Methoxy-2-phenethyloxy-phenyl)-ethyl]-4-pyridin-2-yl-piperazine; compound with oxalic acid::CHEMBL11626 D(2) dopamine receptor Rattus norvegicus 137 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11796233 103968054 CHEMBL11626 ZINC13795866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793528 CCCN(CCC)CCc1ccc(OC)c(OCCCc2ccccc2)c1 InChI=1S/C24H35NO2/c1-4-16-25(17-5-2)18-15-22-13-14-23(26-3)24(20-22)27-19-9-12-21-10-7-6-8-11-21/h6-8,10-11,13-14,20H,4-5,9,12,15-19H2,1-3H3 KWBSGRNMMKLDML-UHFFFAOYSA-N 50074853 CHEMBL11182::{2-[4-Methoxy-3-(3-phenyl-propoxy)-phenyl]-ethyl}-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10619108 103968045 CHEMBL11182 ZINC13795847 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793529 CCCN(CCC)CCCc1ccc(OC)c(OCCc2ccccc2)c1 InChI=1S/C24H35NO2/c1-4-16-25(17-5-2)18-9-12-22-13-14-23(26-3)24(20-22)27-19-15-21-10-7-6-8-11-21/h6-8,10-11,13-14,20H,4-5,9,12,15-19H2,1-3H3 PEHAMGDRVOBROR-UHFFFAOYSA-N 50074846 CHEMBL545597::[3-(4-Methoxy-3-phenethyloxy-phenyl)-propyl]-dipropyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus 950 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074846&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10690470 103968038 CHEMBL545597 ZINC13795797 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793538 CCCN(CCC)CCc1cccc(OC)c1OCc1ccccc1 InChI=1S/C22H31NO2/c1-4-15-23(16-5-2)17-14-20-12-9-13-21(24-3)22(20)25-18-19-10-7-6-8-11-19/h6-13H,4-5,14-18H2,1-3H3 MXBGLJHSBKQHOA-UHFFFAOYSA-N 50074883 CHEMBL262955::[2-(2-Benzyloxy-3-methoxy-phenyl)-ethyl]-dipropyl-amine; compound with oxalic acid D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074883&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10617226 103968075 CHEMBL262955 ZINC13795717 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793541 CCCN(CCC)CCc1cc(OC)ccc1OCCc1ccccc1 InChI=1S/C23H33NO2/c1-4-15-24(16-5-2)17-13-21-19-22(25-3)11-12-23(21)26-18-14-20-9-7-6-8-10-20/h6-12,19H,4-5,13-18H2,1-3H3 ZWTWRVYQKOMVFY-UHFFFAOYSA-N 50074856 CHEMBL537251::[2-(5-Methoxy-2-phenethyloxy-phenyl)-ethyl]-dipropyl-amine; hydrochloride D(2) dopamine receptor Rattus norvegicus 791 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10784426 103968048 CHEMBL537251 ZINC13795731 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793542 COc1ccc(CCN2CCN(CC2)c2ccccn2)cc1OCCc1ccccc1 InChI=1S/C26H31N3O2/c1-30-24-11-10-23(21-25(24)31-20-13-22-7-3-2-4-8-22)12-15-28-16-18-29(19-17-28)26-9-5-6-14-27-26/h2-11,14,21H,12-13,15-20H2,1H3 AACNPPGIALSYEJ-UHFFFAOYSA-N 50074864 1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-4-pyridin-2-yl-piperazine; compound with oxalic acid::CHEMBL11640 D(2) dopamine receptor Rattus norvegicus 295 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10621890 103968056 CHEMBL11640 ZINC13795785 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793544 COc1ccc(CCN2CCN(CC2)c2ccccc2)cc1OCCc1ccccc1 InChI=1S/C27H32N2O2/c1-30-26-13-12-24(22-27(26)31-21-15-23-8-4-2-5-9-23)14-16-28-17-19-29(20-18-28)25-10-6-3-7-11-25/h2-13,22H,14-21H2,1H3 IIYBUMVBOAURQO-UHFFFAOYSA-N 50074881 1-[2-(4-Methoxy-3-phenethyloxy-phenyl)-ethyl]-4-phenyl-piperazine; compound with oxalic acid::CHEMBL11304 D(2) dopamine receptor Rattus norvegicus 183 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50074881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50074881&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10788071 103968073 CHEMBL11304 ZINC13795782 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50793546 OC(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1 InChI=1S/C18H22F2N4O/c19-15-5-3-14(4-6-15)17(25)2-1-7-23-8-10-24(11-9-23)18-21-12-16(20)13-22-18/h3-6,12-13,17,25H,1-2,7-11H2 ZXUYYZPJUGQHLQ-UHFFFAOYSA-N 50002238 (R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::(S)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-1-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol(BMY-14802)::1-(4-Fluoro-phenyl)-4-[4-(4-fluoro-phenyl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol::1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-yl)-piperazin-1-yl]-butan-1-ol(BMY-14802)::1-(4-fluorophenyl)-4-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl)butan-1-ol::4-{4-[5-Fluoro-2-(4-fluoro-phenyl)-2H-pyrimidin-1-yl]-piperazin-1-yl}-butan-1-ol::4-{4-[5-Fluoro-2-(4-fluoro-phenyl)-2H-pyrimidin-1-yl]-piperazin-1-yl}-butan-1-ol(BMY 14802)::BMY-14802::CHEMBL60859 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm980212v 10.7270/Q29C6Z4V 10090790 Nakazato, A; Ohta, K; Sekiguchi, Y; Okuyama, S; Chaki, S; Kawashima, Y; Hatayama, K Taisho Pharmaceutical Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002238 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002238&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 108046 103916544 CHEMBL60859 8 ZINC03995923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796097 C[N@@H+]1C[C@@H](C=C2[C@H]1Cc1c[nH]c3cccc2c13)C(N)=O InChI=1S/C16H17N3O/c1-19-8-10(16(17)20)5-12-11-3-2-4-13-15(11)9(7-18-13)6-14(12)19/h2-5,7,10,14,18H,6,8H2,1H3,(H2,17,20)/p+1/t10-,14-/m1/s1 GENAHGKEFJLNJB-QMTHXVAHSA-O 50091033 9-Carbamoyl-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-7-ium(alpha-ergocriptine)::d-Lysergic acid amide D(2) dopamine receptor Rattus norvegicus 2.8 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332913 103989454 4819 C09160 ZINC56727892 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796106 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 370 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796113 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796125 CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18+/m0/s1 BKRGVLQUQGGVSM-KBXCAEBGSA-N 50056445 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea::CHEMBL157138::N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea::lisuride::lisuride, (S) D(2) dopamine receptor Rattus norvegicus 0.60 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search H8G 7WC7,7UM6,6DRX 28864 103952701 51164 CHEMBL157138 DB00589 43 ZINC03831001 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796126 CCCN1Cc2c(C)cccc2[C@H]2[C@H]1CCc1cc(O)c(O)cc21 InChI=1S/C21H25NO2/c1-3-9-22-12-17-13(2)5-4-6-15(17)21-16-11-20(24)19(23)10-14(16)7-8-18(21)22/h4-6,10-11,18,21,23-24H,3,7-9,12H2,1-2H3/t18-,21-/m1/s1 IURHNFGBYOFFDB-WIYYLYMNSA-N 50032516 (6aR,12bS)-4-Methyl-6-propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-4-methyl-6-propyl-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(4-MNP-DHX)::CHEMBL104141 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50032516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50032516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10314127 103941014 CHEMBL104141 ZINC13478192 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796130 Oc1cc2[C@H](CN(CC=C)CCc2c(Br)c1O)c1ccccc1 InChI=1S/C19H20BrNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m1/s1 KKZGFVAZUKHFAC-MRXNPFEDSA-N 50004921 (R)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)6-Br-APB)::CHEMBL34095::R-(+)6-Br-APD3-Allyl-6-bromo-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol D(2) dopamine receptor Rattus norvegicus 480 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10452020 103918468 CHEMBL34095 ZINC02530683 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796136 [NH3+][C@@H]1CCc2cc(O)c(O)cc2C1 InChI=1S/C10H13NO2/c11-8-2-1-6-4-9(12)10(13)5-7(6)3-8/h4-5,8,12-13H,1-3,11H2/p+1/t8-/m1/s1 ASXGAOFCKGHGMF-MRVPVSSYSA-O 50091032 6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl-ammonium(R(+)ADTN)::Aminotetralin-6,7-dihydroxy-(+) D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332855 103989453 ZINC03872369 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796141 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 37000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796142 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 2300 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796148 COc1cc(CC[NH3+])ccc1O InChI=1S/C9H13NO2/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,11H,4-5,10H2,1H3/p+1 DIVQKHQLANKJQO-UHFFFAOYSA-O 50091035 2-(4-Hydroxy-3-methoxy-phenyl)-ethyl-ammonium(3-methoxytyramine)::3-O-methyldopamine D(2) dopamine receptor Rattus norvegicus 225000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6927014 103989456 58001 C05587 ZINC00119675 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796150 CCCN(CCC)[C@@H]1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3/t15-/m1/s1 BLYMJBIZMIGWFK-OAHLLOKOSA-N 50054067 (2R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(7-Hydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-ammonium(R(+)7OH-DPAT)::(R)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::(R)-7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol.HCl::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::CHEMBL301559 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50054067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50054067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603867 103950725 CHEMBL301559 ZINC03870310 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796151 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Rattus norvegicus 45 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796154 Oc1cc2[C@H](C[NH2+]CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2/p+1/t13-/m1/s1 GHWJEDJMOVUXEC-CYBMUJFWSA-O 50067726 (R)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(6-Cl-PB)::SKF 81297 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50067726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50067726&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332751 103962153 ZINC03783980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796157 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Rattus norvegicus 3500 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796158 Oc1cc2[C@H](CN(CC=C)CCc2c(Cl)c1O)c1ccccc1 InChI=1S/C19H20ClNO2/c1-2-9-21-10-8-14-15(11-17(22)19(23)18(14)20)16(12-21)13-6-4-3-5-7-13/h2-7,11,16,22-23H,1,8-10,12H2/t16-/m1/s1 HJWHHQIVUHOBQN-MRXNPFEDSA-N 50049048 (R)-3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-3-Allyl-6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::3-Allyl-6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(Cl-APB)::CHEMBL317741::SK&F-82958::SK-82958 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50049048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50049048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331310 103979426 CHEMBL317741 ZINC03870318 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796168 CCCN(CCc1ccccc1)C1CCc2c(O)cccc2C1 InChI=1S/C21H27NO/c1-2-14-22(15-13-17-7-4-3-5-8-17)19-11-12-20-18(16-19)9-6-10-21(20)23/h3-10,19,23H,2,11-16H2,1H3 DEYFWGXTPWNADC-UHFFFAOYSA-N 50010289 (R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(RS)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL109684::N-0434 D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010289&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1240 103923108 CHEMBL109684 ZINC02169418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796171 Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 InChI=1S/C16H16ClNO3/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21/h1-4,7,13,18-21H,5-6,8H2 TVURRHSHRRELCG-UHFFFAOYSA-N 60917 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::FENOLDOPAM::FENOLDOPAM MESYLATE::MLS001401388::SMR000469190::cid_49659 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G3C 7CKW,7X2C 3341 252640133 DB00800 C07693 ZINC22116612 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796173 CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C InChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1 OZVBMTJYIDMWIL-AYFBDAFISA-N 81993 BROMOCRIPTINE::Bromocriptine+ (GTP+)::Bromocriptine+ (GTP-) D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm990526y 10.7270/Q24J0FS2 10956209 Wilcox, RE; Huang, WH; Brusniak, MY; Wilcox, DM; Pearlman, RS; Teeter, MM; DuRand, CJ; Wiens, BL; Neve, KA University of Texas http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08Y 6VMS,3UA1,7JVR,5VCG 31101 131342567 DB01200 C06856 ZINC53683151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50803214 CN(C)CCc1c(C)[nH]c2cccc(NC(=O)c3ccc(F)cc3)c12 InChI=1S/C20H22FN3O/c1-13-16(11-12-24(2)3)19-17(22-13)5-4-6-18(19)23-20(25)14-7-9-15(21)10-8-14/h4-10,22H,11-12H2,1-3H3,(H,23,25) WMCLJWPYJWRZJT-UHFFFAOYSA-N 50106482 CHEMBL339980::N-[3-(2-Dimethylamino-ethyl)-2-methyl-1H-indol-4-yl]-4-fluoro-benzamide D(2) dopamine receptor Rattus norvegicus 38000 ChEMBL 10.1021/jm0155190 10.7270/Q22Z168B 11708905 Xu, YC; Johnson, KW; Phebus, LA; Cohen, M; Nelson, DL; Schenck, K; Walker, CD; Fritz, JE; Kaldor, SW; LeTourneau, ME; Murff, RE; Zgombick, JM; Calligaro, DO; Audia, JE; Schaus, JM Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106482&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44352308 104002017 CHEMBL339980 ZINC27319374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50794946 COc1cc2CCN(C)CCc3c(Cc2cc1OC)[nH]c1ccccc31 InChI=1S/C22H26N2O2/c1-24-10-8-15-13-21(25-2)22(26-3)14-16(15)12-20-18(9-11-24)17-6-4-5-7-19(17)23-20/h4-7,13-14,23H,8-12H2,1-3H3 ILLDXVCWSLGVJR-UHFFFAOYSA-N 50088340 2,3-dimethoxy-7-methyl-6,7,8,9,14,15-hexahydro-5H-benzo[7,8]azecino[5,4-b]indole::CHEMBL63063 D(2) dopamine receptor Rattus norvegicus 730 ChEMBL 10.1021/jm9911478 10.7270/Q2C53MJH 10821720 Witt, T; Hock, FJ; Lehmann, J University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10807793 103987264 CHEMBL63063 ZINC13808576 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50794955 CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccccc21 InChI=1S/C20H22N2/c1-22-12-10-15-6-2-3-7-16(15)14-20-18(11-13-22)17-8-4-5-9-19(17)21-20/h2-9,21H,10-14H2,1H3 YEWGIGCYIAMFMA-UHFFFAOYSA-N 50088341 11-methyl-11,21-diazatetracyclo[12.7.0.0^{3,8}.0^{15,20}]henicosa-1(14),3(8),4,6,15,17,19-heptaene::7-Methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]-benzazecine::7-methyl-6,7,8,9,14,15-hexahydro-5H-benzo[7,8]azecino[5,4-b]indole(LE 300)::7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]benzazecine::CHEMBL441618::LE 300 D(2) dopamine receptor Rattus norvegicus 6 ChEMBL 10.1021/jm9911478 10.7270/Q2C53MJH 10821720 Witt, T; Hock, FJ; Lehmann, J University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4350931 103987265 CHEMBL441618 ZINC01486281 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50794957 CN1CCc2c(Cc3[nH]c4ccccc4c3CC1)[nH]c1ccccc21 InChI=1S/C22H23N3/c1-25-12-10-17-15-6-2-4-8-19(15)23-21(17)14-22-18(11-13-25)16-7-3-5-9-20(16)24-22/h2-9,23-24H,10-14H2,1H3 FPGUOUPJSRGOEB-UHFFFAOYSA-N 50088344 7-methyl-5,6,7,8,9,14,15,16-octahydroindolo[2',3':7,8]azecino[5,4-b]indole::CHEMBL62529 D(2) dopamine receptor Rattus norvegicus 79 ChEMBL 10.1021/jm9911478 10.7270/Q2C53MJH 10821720 Witt, T; Hock, FJ; Lehmann, J University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50088344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50088344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10830233 103987268 CHEMBL62529 ZINC13808578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50794958 CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1 ZZJYIKPMDIWRSN-TZBSWOFLSA-N 50366495 (+)butaclamol::CHEMBL1255588 D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1021/jm9911478 10.7270/Q2C53MJH 10821720 Witt, T; Hock, FJ; Lehmann, J University of Bonn http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37461 160845597 73298 CHEMBL1255588 ZINC01481744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796330 CC(C)c1ccc(CN2CCN(CC2)C(c2ccc(F)cc2)c2ccc(F)cc2)c(O)\c(c1)=N\CCO InChI=1S/C30H35F2N3O2/c1-21(2)24-3-4-25(30(37)28(19-24)33-13-18-36)20-34-14-16-35(17-15-34)29(22-5-9-26(31)10-6-22)23-7-11-27(32)12-8-23/h3-12,19,21,29,36H,13-18,20H2,1-2H3,(H,33,37) UVPCKMJVJLKETQ-UHFFFAOYSA-N 50091592 7-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-ylmethyl}-2-(2-hydroxy-ethylamino)-4-isopropyl-cyclohepta-2,4,6-trienone(U-92032)::CHEMBL327057::U-92032 D(2) dopamine receptor Rattus norvegicus 1690 ChEMBL 10.1021/jm000143w 10.7270/Q27945CD 10978184 Annoura, H; Nakanishi, K; Toba, T; Takemoto, N; Imajo, S; Miyajima, A; Tamura-Horikawa, Y; Tamura, S Suntory Biomedical Research Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091592&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 132417 103989833 CHEMBL327057 ZINC27074202 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796332 Fc1ccc(cc1)C(N1CCN(C\C=C\c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C26H26F2N2/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21/h1-15,26H,16-20H2/b7-4+ SMANXXCATUTDDT-QPJJXVBHSA-N 50017702 1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-((E)-3-phenyl-allyl)-piperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-(3-phenyl-allyl)-piperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-(3-phenyl-allyl)-piperazine(flunarizine)::CHEMBL30008::CHEMBL539027::Flunarizine::NCGC00018102::cid_6365505 D(2) dopamine receptor Rattus norvegicus 228 ChEMBL 10.1021/jm000143w 10.7270/Q27945CD 10978184 Annoura, H; Nakanishi, K; Toba, T; Takemoto, N; Imajo, S; Miyajima, A; Tamura-Horikawa, Y; Tamura, S Suntory Biomedical Research Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017702&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 941361 103928970 CHEMBL539027CHEMBL30008 DB04841 ZINC19360739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796335 Cc1cc(OC[C@@H](O)CN2CCN(CC2)c2ccc(Cc3ccc(F)cc3)cc2)c(C)c(C)c1N InChI=1S/C29H36FN3O2/c1-20-16-28(21(2)22(3)29(20)31)35-19-27(34)18-32-12-14-33(15-13-32)26-10-6-24(7-11-26)17-23-4-8-25(30)9-5-23/h4-11,16,27,34H,12-15,17-19,31H2,1-3H3/t27-/m0/s1 BNGQNTZNOYCZSU-MHZLTWQESA-N 50091591 (2S)-1-(4-amino-2,3,5-trimethylphenoxy)-3-{4-[4-(4-flourobenzyl)phenyl]-1-piperazinyl}-2-propanol dimethanesulfonate(SUN N8075)::CHEMBL325689 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm000143w 10.7270/Q27945CD 10978184 Annoura, H; Nakanishi, K; Toba, T; Takemoto, N; Imajo, S; Miyajima, A; Tamura-Horikawa, Y; Tamura, S Suntory Biomedical Research Limited http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50091591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50091591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9852814 103989832 CHEMBL325689 ZINC22012520 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814645 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.9 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814655 Cn1cc(nn1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C27H30FN7O/c1-32-18-25(30-31-32)20-2-7-26-23(16-20)24(17-35(26)22-5-3-21(28)4-6-22)19-8-11-33(12-9-19)14-15-34-13-10-29-27(34)36/h2-7,16-19H,8-15H2,1H3,(H,29,36) DUTDDZFCPPOWFH-UHFFFAOYSA-N 50122807 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,3]triazol-4-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL328187 D(2) dopamine receptor Rattus norvegicus 310 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9848303 104015426 CHEMBL328187 ZINC01485923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814657 CN1CCN(CC1)[C@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m0/s1 XRYLGRGAWQSVQW-KRWDZBQOSA-N 50007568 1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL303313::OCTOCLOTHEPIN-S D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12765746 103920838 CHEMBL303313 ZINC19368911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814659 Cn1nncc1-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C27H30FN7O/c1-32-26(17-30-31-32)20-2-7-25-23(16-20)24(18-35(25)22-5-3-21(28)4-6-22)19-8-11-33(12-9-19)14-15-34-13-10-29-27(34)36/h2-7,16-19H,8-15H2,1H3,(H,29,36) VHHAXHJBNHCDMA-UHFFFAOYSA-N 50122816 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(3-methyl-3H-[1,2,3]triazol-4-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL97184 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11827039 104015435 CHEMBL97184 ZINC13493010 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814668 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCOC3=O)CC2)c2cc(ccc12)-c1ncccn1 InChI=1S/C28H28FN5O2/c29-22-3-5-23(6-4-22)34-19-25(24-18-21(2-7-26(24)34)27-30-10-1-11-31-27)20-8-12-32(13-9-20)14-15-33-16-17-36-28(33)35/h1-7,10-11,18-20H,8-9,12-17H2 VROFQJNNYWWTGM-UHFFFAOYSA-N 50122808 3-(2-{4-[1-(4-Fluoro-phenyl)-5-pyrimidin-2-yl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-oxazolidin-2-one::CHEMBL95175 D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11092112 104015427 CHEMBL95175 ZINC13493021 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814675 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)-c1cccnc1 InChI=1S/C29H30FN5O/c30-24-4-6-25(7-5-24)35-20-27(26-18-22(3-8-28(26)35)23-2-1-11-31-19-23)21-9-13-33(14-10-21)16-17-34-15-12-32-29(34)36/h1-8,11,18-21H,9-10,12-17H2,(H,32,36) GWZCTNJFVWRKTG-UHFFFAOYSA-N 50122800 1-(2-{4-[1-(4-Fluoro-phenyl)-5-pyridin-3-yl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL94612 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11826976 104015419 CHEMBL94612 ZINC13493014 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814682 Fc1ccc(cc1)-n1cc(C2CCN(CCC#N)CC2)c2cc(ccc12)-c1ncccn1 InChI=1S/C26H24FN5/c27-21-4-6-22(7-5-21)32-18-24(19-9-15-31(16-10-19)14-1-11-28)23-17-20(3-8-25(23)32)26-29-12-2-13-30-26/h2-8,12-13,17-19H,1,9-10,14-16H2 ALBWWALSEOWKRA-UHFFFAOYSA-N 50122806 3-{4-[1-(4-Fluoro-phenyl)-5-pyrimidin-2-yl-1H-indol-3-yl]-piperidin-1-yl}-propionitrile::CHEMBL317333 D(2) dopamine receptor Rattus norvegicus 490 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10310103 104015425 CHEMBL317333 ZINC13493022 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814683 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)-c1nnn[nH]1 InChI=1S/C25H27FN8O/c26-19-2-4-20(5-3-19)34-16-22(21-15-18(1-6-23(21)34)24-28-30-31-29-24)17-7-10-32(11-8-17)13-14-33-12-9-27-25(33)35/h1-6,15-17H,7-14H2,(H,27,35)(H,28,29,30,31) WSVJLBOEXBDQNC-UHFFFAOYSA-N 50122823 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL95169 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122823&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11113505 104015442 CHEMBL95169 ZINC13493015 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814687 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(Cl)ccc12 InChI=1S/C24H26ClFN4O/c25-18-1-6-23-21(15-18)22(16-30(23)20-4-2-19(26)3-5-20)17-7-10-28(11-8-17)13-14-29-12-9-27-24(29)31/h1-6,15-17H,7-14H2,(H,27,31) GZKLJWGUPQBVJQ-UHFFFAOYSA-N 50001786 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one::1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one::CHEMBL12713::Sertindole D(2) dopamine receptor Rattus norvegicus 0.45 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60149 103916159 9122 CHEMBL12713 DB06144 98 C07567 ZINC00538337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796518 CCCN(CCC)C1COc2ccc3nc(N)sc3c2C1 InChI=1S/C16H23N3OS/c1-3-7-19(8-4-2)11-9-12-14(20-10-11)6-5-13-15(12)21-16(17)18-13/h5-6,11H,3-4,7-10H2,1-2H3,(H2,17,18) DSJQTHADLDMTRA-UHFFFAOYSA-N 50092170 CHEMBL116372::N*8*,N*8*-Dipropyl-8,9-dihydro-7H-chromeno[6,5-d]thiazole-2,8-diamine D(2) dopamine receptor Rattus norvegicus 148 ChEMBL 10.1021/jm000087z 10.7270/Q2B27W0T 11000009 van Vliet, LA; Rodenhuis, N; Wikstrom, H; Pugsley, TA; Serpa, KA; Meltzer, LT; Heffner, TG; Wise, LD; Lajiness, ME; Huff, RM; Svensson, K; Haenen, GR; Bast, A University of Maastricht http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10780928 103990360 CHEMBL116372 ZINC13813245 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796522 CCCN(CCC)C1Cc2ccc3nc(N)sc3c2C1 InChI=1S/C16H23N3S/c1-3-7-19(8-4-2)12-9-11-5-6-14-15(13(11)10-12)20-16(17)18-14/h5-6,12H,3-4,7-10H2,1-2H3,(H2,17,18) BAJOTSCRNKRKED-UHFFFAOYSA-N 50092169 CHEMBL118636::N*7*,N*7*-Dipropyl-7,8-dihydro-6H-1-thia-3-aza-as-indacene-2,7-diamine D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm000087z 10.7270/Q2B27W0T 11000009 van Vliet, LA; Rodenhuis, N; Wikstrom, H; Pugsley, TA; Serpa, KA; Meltzer, LT; Heffner, TG; Wise, LD; Lajiness, ME; Huff, RM; Svensson, K; Haenen, GR; Bast, A University of Maastricht http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10637198 103990359 CHEMBL118636 ZINC13813263 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807541 OCCN1CCN(CC1)C1Cn2cccc2Sc2ccc(Br)cc12 InChI=1S/C18H22BrN3OS/c19-14-3-4-17-15(12-14)16(13-22-5-1-2-18(22)24-17)21-8-6-20(7-9-21)10-11-23/h1-5,12,16,23H,6-11,13H2 ZAYWFUSENFQTME-UHFFFAOYSA-N 50108594 (+/-)2-[4-(7-Bromo-9,10-dihydro-4-thia-10a-aza-benzo[f]azulen-9-yl)-piperazin-1-yl]-ethanol::CHEMBL116542 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10894826 104003812 CHEMBL116542 ZINC22925283 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807543 OCCN1CCN(CC1)C1Cn2cccc2Sc2ccc(F)cc12 InChI=1S/C18H22FN3OS/c19-14-3-4-17-15(12-14)16(13-22-5-1-2-18(22)24-17)21-8-6-20(7-9-21)10-11-23/h1-5,12,16,23H,6-11,13H2 YHNPEPCGBKSLOS-UHFFFAOYSA-N 50108591 (+/-)2-[4-(7-Fluoro-9,10-dihydro-4-thia-10a-aza-benzo[f]azulen-9-yl)-piperazin-1-yl]-ethanol::CHEMBL118919 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9819674 104003809 CHEMBL118919 ZINC22925258 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807547 CN1CCN(CC1)C1Cn2cccc2Sc2ccc(F)cc12 InChI=1S/C17H20FN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11,15H,7-10,12H2,1H3 FNXVFVIKVBLUPH-UHFFFAOYSA-N 50108593 (+/-)7-Fluoro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(R)-(-)7-Fluoro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(S)-(+)7-Fluoro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene(ST1615)::CHEMBL332600 D(2) dopamine receptor Rattus norvegicus 23.7 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108593&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9883454 104003811 CHEMBL332600 ZINC22925219 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807558 CN1CCN(CC1)C1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3 XRYLGRGAWQSVQW-UHFFFAOYSA-N 22872 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methyl-piperazine;maleate::1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine::1-{6-chloro-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-9-yl}-4-methylpiperazine::CHEMBL64249::CLOROTEPINE (+)::CLOROTEPINE(-)::Clothepin::OCTOCLOTHEPIN,(+)::OCTOCLOTHEPIN,(-)::Octoclothepin::Octoclothepine D(2) dopamine receptor Rattus norvegicus 0.5 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1238 49846686 CHEMBL64249 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807560 CCN1CCN(CC1)C1Cn2cccc2Sc2ccc(F)cc12 InChI=1S/C18H22FN3S/c1-2-20-8-10-21(11-9-20)16-13-22-7-3-4-18(22)23-17-6-5-14(19)12-15(16)17/h3-7,12,16H,2,8-11,13H2,1H3 HXNZZHNYAXGYCA-UHFFFAOYSA-N 50108592 (+/-)9-(4-Ethyl-piperazin-1-yl)-7-fluoro-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL333455 D(2) dopamine receptor Rattus norvegicus 9.5 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108592&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9949441 104003810 CHEMBL333455 ZINC22925248 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807566 CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m1/s1 XRYLGRGAWQSVQW-QGZVFWFLSA-N 50007567 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL64875::OCTOCLOTHEPIN-R D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603950 103920837 CHEMBL64875 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807568 CN1CCCN(CC1)C1Cn2cccc2Sc2ccc(Cl)cc12 InChI=1S/C18H22ClN3S/c1-20-7-3-9-21(11-10-20)16-13-22-8-2-4-18(22)23-17-6-5-14(19)12-15(16)17/h2,4-6,8,12,16H,3,7,9-11,13H2,1H3 MTLBWLDYHWAFEN-UHFFFAOYSA-N 50108598 (+/-)7-Chloro-9-(4-methyl-[1,4]diazepan-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL118092 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108598&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11782988 104003816 CHEMBL118092 ZINC22778615 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807574 CCN1CCN(CC1)C1Cn2cccc2Sc2ccc(Cl)cc12 InChI=1S/C18H22ClN3S/c1-2-20-8-10-21(11-9-20)16-13-22-7-3-4-18(22)23-17-6-5-14(19)12-15(16)17/h3-7,12,16H,2,8-11,13H2,1H3 KVCCOUNQAONHEJ-UHFFFAOYSA-N 50108590 (+/-)7-Chloro-9-(4-ethyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL118889 D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108590&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11089340 104003808 CHEMBL118889 ZINC22925229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807577 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807600 CN1CCN(CC1)[C@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m0/s1 XRYLGRGAWQSVQW-KRWDZBQOSA-N 50007568 1-((S)-8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL303313::OCTOCLOTHEPIN-S D(2) dopamine receptor Rattus norvegicus 0.4 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12765746 103920838 CHEMBL303313 ZINC19368911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807603 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807611 CN1CCN(CC1)C1Cn2cccc2Sc2ccccc12 InChI=1S/C17H21N3S/c1-18-9-11-19(12-10-18)15-13-20-8-4-7-17(20)21-16-6-3-2-5-14(15)16/h2-8,15H,9-13H2,1H3 PUSGNVOFKAPWQM-UHFFFAOYSA-N 50066912 (+/-)9-(4-Methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(R)-(-)9-(4-Methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(S)-(+)9-(4-Methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene(ST1622)::9-(4-Methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL333246 D(2) dopamine receptor Rattus norvegicus 79 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066912&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817779 103961448 CHEMBL333246 ZINC22778669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807620 CCN1CCN(CC1)C1Cn2cccc2Sc2ccc(Br)cc12 InChI=1S/C18H22BrN3S/c1-2-20-8-10-21(11-9-20)16-13-22-7-3-4-18(22)23-17-6-5-14(19)12-15(16)17/h3-7,12,16H,2,8-11,13H2,1H3 PHGLWACKDGVPPP-UHFFFAOYSA-N 50108597 (+/-)7-Bromo-9-(4-ethyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL333955 D(2) dopamine receptor Rattus norvegicus 4 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108597&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11014679 104003815 CHEMBL333955 ZINC22925275 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807635 CN1CCN(CC1)C1Cn2cccc2Sc2ccc(Br)cc12 InChI=1S/C17H20BrN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11,15H,7-10,12H2,1H3 ZMGDSWCUJROUAZ-UHFFFAOYSA-N 50108595 (+/-)7-Bromo-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL121274 D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10981731 104003813 CHEMBL121274 ZINC22925267 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807637 OCCN1CCN(CC1)C1Cn2cccc2Sc2ccc(Cl)cc12 InChI=1S/C18H22ClN3OS/c19-14-3-4-17-15(12-14)16(13-22-5-1-2-18(22)24-17)21-8-6-20(7-9-21)10-11-23/h1-5,12,16,23H,6-11,13H2 IKILHTNIHYFIHG-UHFFFAOYSA-N 50108596 (+/-)2-[4-(7-Chloro-9,10-dihydro-4-thia-10a-aza-benzo[f]azulen-9-yl)-piperazin-1-yl]-ethanol::CHEMBL119687 D(2) dopamine receptor Rattus norvegicus 6 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108596&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11728201 104003814 CHEMBL119687 ZINC22925238 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807641 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.8 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50807643 CN1CCN(CC1)C1Cn2cccc2Sc2ccc(Cl)cc12 InChI=1S/C17H20ClN3S/c1-19-7-9-20(10-8-19)15-12-21-6-2-3-17(21)22-16-5-4-13(18)11-14(15)16/h2-6,11,15H,7-10,12H2,1H3 YQXNPUPTPJOJOV-UHFFFAOYSA-N 50066910 (+/-)7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(R)-(-)7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::(S)-(+)-7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene(ST1460)::7-Chloro-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene::CHEMBL120512 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1021/jm010982y 10.7270/Q2TX3G26 11784139 Campiani, G; Butini, S; Gemma, S; Nacci, V; Fattorusso, C; Catalanotti, B; Giorgi, G; Cagnotto, A; Goegan, M; Mennini, T; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50066910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50066910&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9884087 103961446 CHEMBL120512 ZINC22925209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814692 Cn1nccc1-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C28H31FN6O/c1-32-26(8-11-31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-9-13-33(14-10-20)16-17-34-15-12-30-28(34)36/h2-8,11,18-20H,9-10,12-17H2,1H3,(H,30,36) YMAOXQVSFQEHJK-UHFFFAOYSA-N 50122802 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-pyrazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL328048 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11016395 104015421 CHEMBL328048 ZINC13493008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814694 Cn1nnc(n1)-c1ccc2n(cc(C3CCN(CCN4CCOC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C26H28FN7O2/c1-31-29-25(28-30-31)19-2-7-24-22(16-19)23(17-34(24)21-5-3-20(27)4-6-21)18-8-10-32(11-9-18)12-13-33-14-15-36-26(33)35/h2-7,16-18H,8-15H2,1H3 SPHRCFFKJXRWLW-UHFFFAOYSA-N 50122813 3-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-oxazolidin-2-one::CHEMBL97242 D(2) dopamine receptor Rattus norvegicus 190 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10917953 104015432 CHEMBL97242 ZINC13493017 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814706 Cn1cnc(n1)-c1ccc2n(cc(C3CCN(CCC#N)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C25H25FN6/c1-30-17-28-25(29-30)19-3-8-24-22(15-19)23(16-32(24)21-6-4-20(26)5-7-21)18-9-13-31(14-10-18)12-2-11-27/h3-8,15-18H,2,9-10,12-14H2,1H3 FVDPLVKCBNWFME-UHFFFAOYSA-N 50122810 3-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-propionitrile::CHEMBL420997 D(2) dopamine receptor Rattus norvegicus >2900 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9910451 104015429 CHEMBL420997 ZINC01554072 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814709 CN1CCN(CC1)[C@@H]1Cc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C19H21ClN2S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19/h2-7,13,17H,8-12H2,1H3/t17-/m1/s1 XRYLGRGAWQSVQW-QGZVFWFLSA-N 50007567 1-(8-Chloro-10,11-dihydro-dibenzo[b,f]thiepin-10-yl)-4-methyl-piperazine::CHEMBL64875::OCTOCLOTHEPIN-R D(2) dopamine receptor Rattus norvegicus 6.6 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603950 103920837 CHEMBL64875 ZINC22032760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814720 Cn1cnc(n1)-c1ccc2n(cc(C3CCN(CCn4c(=O)[nH]c5ccccc5c4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C32H30FN7O2/c1-37-20-34-30(36-37)22-6-11-29-26(18-22)27(19-40(29)24-9-7-23(33)8-10-24)21-12-14-38(15-13-21)16-17-39-31(41)25-4-2-3-5-28(25)35-32(39)42/h2-11,18-21H,12-17H2,1H3,(H,35,42) SQHPLCBBYWXCOO-UHFFFAOYSA-N 50122817 3-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-1H-quinazoline-2,4-dione::CHEMBL318901 D(2) dopamine receptor Rattus norvegicus 370 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10973768 104015436 CHEMBL318901 ZINC26721222 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814721 Cn1cc(cn1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C28H31FN6O/c1-32-18-22(17-31-32)21-2-7-27-25(16-21)26(19-35(27)24-5-3-23(29)4-6-24)20-8-11-33(12-9-20)14-15-34-13-10-30-28(34)36/h2-7,16-20H,8-15H2,1H3,(H,30,36) BJICDRUQIDTHQQ-UHFFFAOYSA-N 50122804 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazol-4-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL329280 D(2) dopamine receptor Rattus norvegicus 570 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122804&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11812916 104015423 CHEMBL329280 ZINC13493004 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814724 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)-c1c[nH]nn1 InChI=1S/C26H28FN7O/c27-20-2-4-21(5-3-20)34-17-23(22-15-19(1-6-25(22)34)24-16-29-31-30-24)18-7-10-32(11-8-18)13-14-33-12-9-28-26(33)35/h1-6,15-18H,7-14H2,(H,28,35)(H,29,30,31) TZCZMKAONNBNIA-UHFFFAOYSA-N 50122822 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2H-[1,2,3]triazol-4-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL97422 D(2) dopamine receptor Rattus norvegicus 80 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11123573 104015441 CHEMBL97422 ZINC13493016 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814728 CCn1ncc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C28H32FN7O/c1-2-36-31-18-26(32-36)21-3-8-27-24(17-21)25(19-35(27)23-6-4-22(29)5-7-23)20-9-12-33(13-10-20)15-16-34-14-11-30-28(34)37/h3-8,17-20H,2,9-16H2,1H3,(H,30,37) NEBSYJAENXRLFM-UHFFFAOYSA-N 50122820 1-(2-{4-[5-(2-Ethyl-2H-[1,2,3]triazol-4-yl)-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL330171 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122820&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9827354 104015439 CHEMBL330171 ZINC13493001 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814748 C[C@H](CN1CCN(CC1)c1cc(F)c(F)cc1F)N1C(=O)CC2(CCCC2)CC1=O InChI=1S/C22H28F3N3O2/c1-15(28-20(29)12-22(13-21(28)30)4-2-3-5-22)14-26-6-8-27(9-7-26)19-11-17(24)16(23)10-18(19)25/h10-11,15H,2-9,12-14H2,1H3/t15-/m1/s1 WCWNYVYNQAPOOX-OAHLLOKOSA-N 50122803 (SNAP-8719)[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone::8-{(R)-1-Methyl-2-[4-(2,4,5-trifluoro-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione::8-{1-Methyl-2-[4-(2,4,5-trifluoro-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione::CHEMBL98241::SNAP-8719 D(2) dopamine receptor Rattus norvegicus 970 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9845181 104015422 CHEMBL98241 ZINC53165105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50796540 CCCN(CCC)C1Cc2cc3nc(N)sc3cc2C1 InChI=1S/C16H23N3S/c1-3-5-19(6-4-2)13-7-11-9-14-15(10-12(11)8-13)20-16(17)18-14/h9-10,13H,3-8H2,1-2H3,(H2,17,18) REAPOTFJKWYQFW-UHFFFAOYSA-N 50092173 CHEMBL325710::N*6*,N*6*-Dipropyl-6,7-dihydro-5H-1-thia-3-aza-s-indacene-2,6-diamine D(2) dopamine receptor Rattus norvegicus 5.7 ChEMBL 10.1021/jm000087z 10.7270/Q2B27W0T 11000009 van Vliet, LA; Rodenhuis, N; Wikstrom, H; Pugsley, TA; Serpa, KA; Meltzer, LT; Heffner, TG; Wise, LD; Lajiness, ME; Huff, RM; Svensson, K; Haenen, GR; Bast, A University of Maastricht http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50092173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50092173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9904074 103990363 CHEMBL325710 ZINC13813258 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814769 Cn1cnc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C27H30FN7O/c1-32-18-30-26(31-32)20-2-7-25-23(16-20)24(17-35(25)22-5-3-21(28)4-6-22)19-8-11-33(12-9-19)14-15-34-13-10-29-27(34)36/h2-7,16-19H,8-15H2,1H3,(H,29,36) CBFLLWSFCPBXDU-UHFFFAOYSA-N 50122811 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL327527 D(2) dopamine receptor Rattus norvegicus 660 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10917920 104015430 CHEMBL327527 ZINC13493005 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814785 Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36) DVICNJMXCZEIQX-UHFFFAOYSA-N 50122799 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL93923 D(2) dopamine receptor Rattus norvegicus 490 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11049209 104015418 CHEMBL93923 ZINC13493003 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814790 Cn1ccnc1-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C28H31FN6O/c1-32-14-10-30-27(32)21-2-7-26-24(18-21)25(19-35(26)23-5-3-22(29)4-6-23)20-8-12-33(13-9-20)16-17-34-15-11-31-28(34)36/h2-7,10,14,18-20H,8-9,11-13,15-17H2,1H3,(H,31,36) FFQNIRWMHOFXPG-UHFFFAOYSA-N 50122798 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-imidazol-2-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL318735 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122798&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10896220 104015417 CHEMBL318735 ZINC13493009 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814792 CN1CCC(CCN2CCC(CC2)c2cn(-c3ccc(F)cc3)c3ccc(cc23)-c2ncn(C)n2)C1=O InChI=1S/C29H33FN6O/c1-33-13-9-21(29(33)37)12-16-35-14-10-20(11-15-35)26-18-36(24-6-4-23(30)5-7-24)27-8-3-22(17-25(26)27)28-31-19-34(2)32-28/h3-8,17-21H,9-16H2,1-2H3 NLEVDCFBQNJLSW-UHFFFAOYSA-N 50122809 3-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-1-methyl-pyrrolidin-2-one::CHEMBL97333 D(2) dopamine receptor Rattus norvegicus 540 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11071135 104015428 CHEMBL97333 ZINC13493020 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814795 Cn1nnnc1-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C26H29FN8O/c1-32-25(29-30-31-32)19-2-7-24-22(16-19)23(17-35(24)21-5-3-20(27)4-6-21)18-8-11-33(12-9-18)14-15-34-13-10-28-26(34)36/h2-7,16-18H,8-15H2,1H3,(H,28,36) KZPAEJGLSCXYBV-UHFFFAOYSA-N 50122825 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL330603 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122825&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11038263 104015444 CHEMBL330603 ZINC13493011 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814796 Cn1ncc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C27H30FN7O/c1-32-30-17-25(31-32)20-2-7-26-23(16-20)24(18-35(26)22-5-3-21(28)4-6-22)19-8-11-33(12-9-19)14-15-34-13-10-29-27(34)36/h2-7,16-19H,8-15H2,1H3,(H,29,36) WOYBCGRCOVCAFT-UHFFFAOYSA-N 50122805 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-[1,2,3]triazol-4-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL328940 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9826761 104015424 CHEMBL328940 ZINC13493000 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814804 Cn1cnnc1-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C27H30FN7O/c1-32-18-30-31-26(32)20-2-7-25-23(16-20)24(17-35(25)22-5-3-21(28)4-6-22)19-8-11-33(12-9-19)14-15-34-13-10-29-27(34)36/h2-7,16-19H,8-15H2,1H3,(H,29,36) FGCMVLRDXLMALY-UHFFFAOYSA-N 50122818 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(4-methyl-4H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL327662 D(2) dopamine receptor Rattus norvegicus 430 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11038248 104015437 CHEMBL327662 ZINC13493006 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814814 Cn1nnc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C26H29FN8O/c1-32-30-25(29-31-32)19-2-7-24-22(16-19)23(17-35(24)21-5-3-20(27)4-6-21)18-8-11-33(12-9-18)14-15-34-13-10-28-26(34)36/h2-7,16-18H,8-15H2,1H3,(H,28,36) USCDVFNXTCISHV-UHFFFAOYSA-N 50122815 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-tetrazol-5-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL319352 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9826801 104015434 CHEMBL319352 ZINC13493002 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814816 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)-c1cncnc1 InChI=1S/C28H29FN6O/c29-23-2-4-24(5-3-23)35-18-26(25-15-21(1-6-27(25)35)22-16-30-19-31-17-22)20-7-10-33(11-8-20)13-14-34-12-9-32-28(34)36/h1-6,15-20H,7-14H2,(H,32,36) IVQOPWPGYZWSKH-UHFFFAOYSA-N 50122819 1-(2-{4-[1-(4-Fluoro-phenyl)-5-pyrimidin-5-yl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL97650 D(2) dopamine receptor Rattus norvegicus 91 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10972931 104015438 CHEMBL97650 ZINC13493013 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814827 CCn1cc(nn1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C28H32FN7O/c1-2-35-19-26(31-32-35)21-3-8-27-24(17-21)25(18-36(27)23-6-4-22(29)5-7-23)20-9-12-33(13-10-20)15-16-34-14-11-30-28(34)37/h3-8,17-20H,2,9-16H2,1H3,(H,30,37) CJGRIFQTJRPEFT-UHFFFAOYSA-N 50122801 1-(2-{4-[5-(1-Ethyl-1H-[1,2,3]triazol-4-yl)-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL318249 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9848876 104015420 CHEMBL318249 ZINC13492999 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814836 Cn1ncnc1-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C27H30FN7O/c1-32-26(30-18-31-32)20-2-7-25-23(16-20)24(17-35(25)22-5-3-21(28)4-6-22)19-8-11-33(12-9-19)14-15-34-13-10-29-27(34)36/h2-7,16-19H,8-15H2,1H3,(H,29,36) CLSRMUGSDHADPG-UHFFFAOYSA-N 50122821 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL98299 D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122821&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11092142 104015440 CHEMBL98299 ZINC13493007 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814843 Cn1cnc(n1)-c1ccc2n(cc(C3CCN(CCN4CCOC4=O)CC3)c2c1)-c1ccc(F)cc1 InChI=1S/C27H29FN6O2/c1-31-18-29-26(30-31)20-2-7-25-23(16-20)24(17-34(25)22-5-3-21(28)4-6-22)19-8-10-32(11-9-19)12-13-33-14-15-36-27(33)35/h2-7,16-19H,8-15H2,1H3 KNLXBMUXNMBWBW-UHFFFAOYSA-N 50122824 3-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-oxazolidin-2-one::CHEMBL313424 D(2) dopamine receptor Rattus norvegicus 2300 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122824&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11016418 104015443 CHEMBL313424 ZINC13493018 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50814851 Fc1ccc(cc1)-n1cc(C2CCN(CCN3CCNC3=O)CC2)c2cc(ccc12)-c1ncccn1 InChI=1S/C28H29FN6O/c29-22-3-5-23(6-4-22)35-19-25(24-18-21(2-7-26(24)35)27-30-10-1-11-31-27)20-8-13-33(14-9-20)16-17-34-15-12-32-28(34)36/h1-7,10-11,18-20H,8-9,12-17H2,(H,32,36) TZOUCQOJXCRYRE-UHFFFAOYSA-N 50122814 1-(2-{4-[1-(4-Fluoro-phenyl)-5-pyrimidin-2-yl-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one::CHEMBL421573 D(2) dopamine receptor Rattus norvegicus 230 ChEMBL 10.1021/jm020938y 10.7270/Q2TB17MV 12519065 Balle, T; Perregaard, J; Ramirez, MT; Larsen, AK; Soby, KK; Liljefors, T; Andersen, K H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11145333 104015433 CHEMBL421573 ZINC13493012 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813765 Clc1ccc(N2CCN(CCCCNC(=O)c3cc4ccccc4[nH]3)CC2)c(Cl)c1 InChI=1S/C23H26Cl2N4O/c24-18-7-8-22(19(25)16-18)29-13-11-28(12-14-29)10-4-3-9-26-23(30)21-15-17-5-1-2-6-20(17)27-21/h1-2,5-8,15-16,27H,3-4,9-14H2,(H,26,30) CYNHGJORJGHXEX-UHFFFAOYSA-N 50131925 1H-Indole-2-carboxylic acid {4-[4-(2,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL339960::N-(4-(4-(2,4-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131925&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10411237 104022950 CHEMBL339960 ZINC03817191 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813767 COc1ccccc1N1CCN(CCNCc2coc(n2)-c2cc3ccccc3o2)CC1 InChI=1S/C25H28N4O3/c1-30-23-9-5-3-7-21(23)29-14-12-28(13-15-29)11-10-26-17-20-18-31-25(27-20)24-16-19-6-2-4-8-22(19)32-24/h2-9,16,18,26H,10-15,17H2,1H3 JCBILKVEETVNCO-UHFFFAOYSA-N 50131927 (2-Benzofuran-2-yl-oxazol-4-ylmethyl)-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amine::CHEMBL341117 D(2) dopamine receptor Rattus norvegicus 518 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131927&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11133813 104022952 CHEMBL341117 ZINC22033650 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813773 COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3o2)CC1 InChI=1S/C24H29N3O3/c1-29-22-11-5-3-9-20(22)27-16-14-26(15-17-27)13-7-6-12-25-24(28)23-18-19-8-2-4-10-21(19)30-23/h2-5,8-11,18H,6-7,12-17H2,1H3,(H,25,28) SIIDHHZTVIEQJK-UHFFFAOYSA-N 50119377 Benzofuran-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL124444::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzofuran-2-carboxamide D(2) dopamine receptor Rattus norvegicus 87 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119377&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10092819 104012595 CHEMBL124444 ZINC03817190 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813777 COc1ccccc1N1CCN(CCNCc2coc(n2)-c2ccc3ccccc3c2)CC1 InChI=1S/C27H30N4O2/c1-32-26-9-5-4-8-25(26)31-16-14-30(15-17-31)13-12-28-19-24-20-33-27(29-24)23-11-10-21-6-2-3-7-22(21)18-23/h2-11,18,20,28H,12-17,19H2,1H3 XISSXEYXFUJWDA-UHFFFAOYSA-N 50131929 CHEMBL123952::{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-(2-naphthalen-2-yl-oxazol-4-ylmethyl)-amine D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131929&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11048488 104022954 CHEMBL123952 ZINC22930293 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813778 COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3[nH]2)CC1 InChI=1S/C24H30N4O2/c1-30-23-11-5-4-10-22(23)28-16-14-27(15-17-28)13-7-6-12-25-24(29)21-18-19-8-2-3-9-20(19)26-21/h2-5,8-11,18,26H,6-7,12-17H2,1H3,(H,25,29) IRVKXZUMTITJIC-UHFFFAOYSA-N 50131922 1H-Indole-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL125916::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131922&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10454026 104022947 CHEMBL125916 ZINC12356361 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813791 COc1ccccc1N1CCN(CCCCNC(=O)c2cnc3ccccc3n2)CC1 InChI=1S/C24H29N5O2/c1-31-23-11-5-4-10-22(23)29-16-14-28(15-17-29)13-7-6-12-25-24(30)21-18-26-19-8-2-3-9-20(19)27-21/h2-5,8-11,18H,6-7,12-17H2,1H3,(H,25,30) PPJBKDPFCCVNFU-UHFFFAOYSA-N 50131932 CHEMBL127344::Quinoxaline-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 84 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131932&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11112574 104022957 CHEMBL127344 ZINC12356410 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813799 COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3cn2)CC1 InChI=1S/C25H30N4O2/c1-31-24-11-5-4-10-23(24)29-16-14-28(15-17-29)13-7-6-12-26-25(30)22-18-20-8-2-3-9-21(20)19-27-22/h2-5,8-11,18-19H,6-7,12-17H2,1H3,(H,26,30) INDXRHKLECFZHX-UHFFFAOYSA-N 50131926 CHEMBL127400::CHEMBL129022::Isoquinoline-3-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 75 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131926&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10895039 104022951 CHEMBL129022CHEMBL127400 ZINC13525815 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813803 COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3n2)CC1 InChI=1S/C25H30N4O2/c1-31-24-11-5-4-10-23(24)29-18-16-28(17-19-29)15-7-6-14-26-25(30)22-13-12-20-8-2-3-9-21(20)27-22/h2-5,8-13H,6-7,14-19H2,1H3,(H,26,30) CDDVHWKFFCJTOZ-UHFFFAOYSA-N 50131934 CHEMBL126439::CHEMBL127317::Quinoline-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 83 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131934&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10862670 104022959 CHEMBL127317CHEMBL126439 ZINC13525812 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813804 Clc1ccc(N2CCN(CCCCNC(=O)c3cc4cc(Cl)ccc4[nH]3)CC2)c(Cl)c1 InChI=1S/C23H25Cl3N4O/c24-17-3-5-20-16(13-17)14-21(28-20)23(31)27-7-1-2-8-29-9-11-30(12-10-29)22-6-4-18(25)15-19(22)26/h3-6,13-15,28H,1-2,7-12H2,(H,27,31) VGPQHQDBSBJSAG-UHFFFAOYSA-N 50131930 5-Chloro-1H-indole-2-carboxylic acid {4-[4-(2,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::5-chloro-N-(4-(4-(2,4-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide::CHEMBL126889 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10367857 104022955 CHEMBL126889 ZINC13525845 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813812 COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1 InChI=1S/C26H31N3O2/c1-31-25-11-5-4-10-24(25)29-18-16-28(17-19-29)15-7-6-14-27-26(30)23-13-12-21-8-2-3-9-22(21)20-23/h2-5,8-13,20H,6-7,14-19H2,1H3,(H,27,30) MNHDKMDLOJSCGN-UHFFFAOYSA-N 50119380 CHEMBL25236::CHEMBL540612::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide::Naphthalene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 61 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3038495 104012598 CHEMBL25236CHEMBL540612 ZINC03917109 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813817 Clc1ccc(N2CCN(CCCCNC(=O)c3cc4ccccc4o3)CC2)c(Cl)c1 InChI=1S/C23H25Cl2N3O2/c24-18-7-8-20(19(25)16-18)28-13-11-27(12-14-28)10-4-3-9-26-23(29)22-15-17-5-1-2-6-21(17)30-22/h1-2,5-8,15-16H,3-4,9-14H2,(H,26,29) GWZLKJUHKRQBRB-UHFFFAOYSA-N 50131923 Benzofuran-2-carboxylic acid {4-[4-(2,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL435218 D(2) dopamine receptor Rattus norvegicus 409 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131923&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10873978 104022948 CHEMBL435218 ZINC13525841 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813822 COc1ccccc1N1CCN(CCCCNC(=O)c2nc3ccccc3n3cccc23)CC1 InChI=1S/C27H31N5O2/c1-34-25-13-5-4-11-23(25)31-19-17-30(18-20-31)15-7-6-14-28-27(33)26-24-12-8-16-32(24)22-10-3-2-9-21(22)29-26/h2-5,8-13,16H,6-7,14-15,17-20H2,1H3,(H,28,33) KWGKDFPPFUUSKQ-UHFFFAOYSA-N 50131935 CHEMBL126590::Pyrrolo[1,2-a]quinoxaline-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131935&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11102533 104022960 CHEMBL126590 ZINC13525819 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813824 COc1ccccc1N1CCN(CCCCN2CCn3c(cc4ccccc34)C2=O)CC1 InChI=1S/C26H32N4O2/c1-32-25-11-5-4-10-23(25)28-16-14-27(15-17-28)12-6-7-13-29-18-19-30-22-9-3-2-8-21(22)20-24(30)26(29)31/h2-5,8-11,20H,6-7,12-19H2,1H3 BUVJSGDYMDZIDN-UHFFFAOYSA-N 50131920 2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one::CHEMBL420510 D(2) dopamine receptor Rattus norvegicus 45 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131920&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11732785 104022945 CHEMBL420510 ZINC12356444 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813834 Clc1ccc(N2CCN(CCCCNC(=O)c3cc4ccccc4cn3)CC2)c(Cl)c1 InChI=1S/C24H26Cl2N4O/c25-20-7-8-23(21(26)16-20)30-13-11-29(12-14-30)10-4-3-9-27-24(31)22-15-18-5-1-2-6-19(18)17-28-22/h1-2,5-8,15-17H,3-4,9-14H2,(H,27,31) BJILZOKLMRTDFN-UHFFFAOYSA-N 50131921 CHEMBL340641::Isoquinoline-3-carboxylic acid {4-[4-(2,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 342 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131921&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11091738 104022946 CHEMBL340641 ZINC13525839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50813836 Clc1ccc(cc1Cl)N1CCN(CCCCNC(=O)c2cc3ccccc3o2)CC1 InChI=1S/C23H25Cl2N3O2/c24-19-8-7-18(16-20(19)25)28-13-11-27(12-14-28)10-4-3-9-26-23(29)22-15-17-5-1-2-6-21(17)30-22/h1-2,5-8,15-16H,3-4,9-14H2,(H,26,29) IMEOUPAOCLGQOG-UHFFFAOYSA-N 50131936 Benzofuran-2-carboxylic acid {4-[4-(3,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL125193 D(2) dopamine receptor Rattus norvegicus 333 ChEMBL 10.1021/jm0211220 10.7270/Q2H132RF 12930145 Campiani, G; Butini, S; Trotta, F; Fattorusso, C; Catalanotti, B; Aiello, F; Gemma, S; Nacci, V; Novellino, E; Stark, JA; Cagnotto, A; Fumagalli, E; Carnovali, F; Cervo, L; Mennini, T Universit£ di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131936&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11812345 104022961 CHEMBL125193 ZINC13525836 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828138 C(C1CCc2ccccc2C1)N1CCC(Cc2ccccc2)CC1 InChI=1S/C23H29N/c1-2-6-19(7-3-1)16-20-12-14-24(15-13-20)18-21-10-11-22-8-4-5-9-23(22)17-21/h1-9,20-21H,10-18H2 FVMIAKGRUAFNMJ-UHFFFAOYSA-N 50159020 4-Benzyl-1-(1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-piperidine::CHEMBL180327 D(2) dopamine receptor Rattus norvegicus 1145 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11405584 104045620 CHEMBL180327 ZINC13607187 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828150 O=C1C(CN2CCC(Cc3ccccc3)CC2)COc2ccccc12 InChI=1S/C22H25NO2/c24-22-19(16-25-21-9-5-4-8-20(21)22)15-23-12-10-18(11-13-23)14-17-6-2-1-3-7-17/h1-9,18-19H,10-16H2 ODWZSCLUZWGCOH-UHFFFAOYSA-N 50159030 3-(4-Benzyl-piperidin-1-ylmethyl)-chroman-4-one::CHEMBL178519 D(2) dopamine receptor Rattus norvegicus 1093 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159030&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11773145 104045630 CHEMBL178519 ZINC13607226 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828153 COc1cccc2CC(CN3CCC(Cc4ccccc4)CC3)CCc12 InChI=1S/C24H31NO/c1-26-24-9-5-8-22-17-21(10-11-23(22)24)18-25-14-12-20(13-15-25)16-19-6-3-2-4-7-19/h2-9,20-21H,10-18H2,1H3 AEUPQCCDJKDASR-UHFFFAOYSA-N 50159031 4-Benzyl-1-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-piperidine::CHEMBL180119 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11372576 104045631 CHEMBL180119 ZINC13607245 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828155 O=C1C(CN2CCC(Cc3ccccc3)CC2)CCCc2ccccc12 InChI=1S/C24H29NO/c26-24-22(11-6-10-21-9-4-5-12-23(21)24)18-25-15-13-20(14-16-25)17-19-7-2-1-3-8-19/h1-5,7-9,12,20,22H,6,10-11,13-18H2 ZGDALBOHMZZJLL-UHFFFAOYSA-N 50159006 6-(4-Benzyl-piperidin-1-ylmethyl)-6,7,8,9-tetrahydro-benzocyclohepten-5-one::CHEMBL179697 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159006&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11234470 104045606 CHEMBL179697 ZINC13607238 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828160 COc1ccc2CC(CN3CCC(Cc4ccccc4)CC3)CCc2c1 InChI=1S/C24H31NO/c1-26-24-10-9-22-16-21(7-8-23(22)17-24)18-25-13-11-20(12-14-25)15-19-5-3-2-4-6-19/h2-6,9-10,17,20-21H,7-8,11-16,18H2,1H3 JLOHHEBPRUDIKQ-UHFFFAOYSA-N 50159025 4-Benzyl-1-(6-methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-piperidine::CHEMBL179530 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159025&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11451971 104045625 CHEMBL179530 ZINC13607250 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828163 C(C1CCc2ccccc2O1)N1CCC(Cc2ccccc2)CC1 InChI=1S/C22H27NO/c1-2-6-18(7-3-1)16-19-12-14-23(15-13-19)17-21-11-10-20-8-4-5-9-22(20)24-21/h1-9,19,21H,10-17H2 XIEPNNMDKPLLAY-UHFFFAOYSA-N 50159024 4-Benzyl-1-chroman-2-ylmethyl-piperidine::CHEMBL178650 D(2) dopamine receptor Rattus norvegicus 924 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11220953 104045624 CHEMBL178650 ZINC13607208 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828170 O=C1C(CN2CCC(Cc3ccccc3)CC2)CCc2ccccc12 InChI=1S/C23H27NO/c25-23-21(11-10-20-8-4-5-9-22(20)23)17-24-14-12-19(13-15-24)16-18-6-2-1-3-7-18/h1-9,19,21H,10-17H2 LTCASCAKDDGTLO-UHFFFAOYSA-N 50159005 2-(4-Benzyl-piperidin-1-ylmethyl)-3,4-dihydro-2H-naphthalen-1-one::CHEMBL434905 D(2) dopamine receptor Rattus norvegicus 1093 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159005&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11234042 104045605 CHEMBL434905 ZINC13607220 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828171 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 6.65 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50819412 CN[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C11H13N3O/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9/h2-4,8,12H,5-6H2,1H3,(H,13,15)/t8-/m1/s1 RKZSNTNMEFVBDT-MRVPVSSYSA-N 50056443 (R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL419792::PNU-95666E D(2) dopamine receptor Rattus norvegicus 10.8 ChEMBL 10.1021/jm030505a 10.7270/Q24B3225 15239663 Cowart, M; Latshaw, SP; Bhatia, P; Daanen, JF; Rohde, J; Nelson, SL; Patel, M; Kolasa, T; Nakane, M; Uchic, ME; Miller, LN; Terranova, MA; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Martino, BR; Lynch, JJ; Sullivan, JP; Hsieh, GC; Moreland, RB; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9818479 103952699 CHEMBL419792 3949 ZINC03960633 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50819423 Fc1ccc2[nH]c(CN3CCN(CC3)c3ccccn3)cc2c1 InChI=1S/C18H19FN4/c19-15-4-5-17-14(11-15)12-16(21-17)13-22-7-9-23(10-8-22)18-3-1-2-6-20-18/h1-6,11-12,21H,7-10,13H2 PQOIDBZLMJMYCD-UHFFFAOYSA-N 50145073 5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1H-indole::CHEMBL77395::CP-226269 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm030505a 10.7270/Q24B3225 15239663 Cowart, M; Latshaw, SP; Bhatia, P; Daanen, JF; Rohde, J; Nelson, SL; Patel, M; Kolasa, T; Nakane, M; Uchic, ME; Miller, LN; Terranova, MA; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Martino, BR; Lynch, JJ; Sullivan, JP; Hsieh, GC; Moreland, RB; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145073&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9796720 104034001 CHEMBL77395 973 ZINC13560675 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50823894 ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ccccn1 InChI=1S/C22H25ClN4O2/c23-20-17-29-19-8-2-1-7-18(19)22(28)27(20)12-6-5-11-25-13-15-26(16-14-25)21-9-3-4-10-24-21/h1-4,7-10,17H,5-6,11-16H2 XIOIYDRBYJBMKK-UHFFFAOYSA-N 50097341 3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-butyl]-4H-benzo[f][1,4]oxazepin-5-one::CHEMBL357266 D(2) dopamine receptor Rattus norvegicus 51 ChEMBL 10.1016/j.bmcl.2005.04.059 10.7270/Q21Z456V 15914001 Kamei, K; Maeda, N; Katsuragi-Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Daiichi Suntory Biomedical Research Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15490956 103994673 CHEMBL357266 ZINC27648061 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50823895 O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 50001859 (buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione : (Hydrochloride)::8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione; Hydrochloride(Buspirone)::8-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione::BUSPAR::BUSPIRONE::CHEMBL49::US10562853, Compound Buspirone D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1016/j.bmcl.2005.04.059 10.7270/Q21Z456V 15914001 Kamei, K; Maeda, N; Katsuragi-Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Daiichi Suntory Biomedical Research Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2477 103916226 3223 CHEMBL49 DB00490 36 C06861 ZINC01530571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50823896 ClC1=COc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1ncccn1 InChI=1S/C21H24ClN5O2/c22-19-16-29-18-7-2-1-6-17(18)20(28)27(19)11-4-3-10-25-12-14-26(15-13-25)21-23-8-5-9-24-21/h1-2,5-9,16H,3-4,10-15H2 MTXWTNUNMLDZTE-UHFFFAOYSA-N 50097343 3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-butyl]-4H-benzo[f][1,4]oxazepin-5-one::CHEMBL347167 D(2) dopamine receptor Rattus norvegicus 199 ChEMBL 10.1016/j.bmcl.2005.04.059 10.7270/Q21Z456V 15914001 Kamei, K; Maeda, N; Katsuragi-Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Daiichi Suntory Biomedical Research Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50097343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50097343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18327916 103994675 CHEMBL347167 ZINC27648485 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50823897 ClC1=COc2ccccc2C(=O)N1CCCCN1CCC(CC1)c1ncccn1 InChI=1S/C22H25ClN4O2/c23-20-16-29-19-7-2-1-6-18(19)22(28)27(20)13-4-3-12-26-14-8-17(9-15-26)21-24-10-5-11-25-21/h1-2,5-7,10-11,16-17H,3-4,8-9,12-15H2 JYKYGGDBYVMQGU-UHFFFAOYSA-N 50167869 3-Chloro-4-[4-(4-pyrimidin-2-yl-piperidin-1-yl)-butyl]-4H-benzo[f][1,4]oxazepin-5-one; hydrochloride::CHEMBL557198 D(2) dopamine receptor Rattus norvegicus 1800 ChEMBL 10.1016/j.bmcl.2005.04.059 10.7270/Q21Z456V 15914001 Kamei, K; Maeda, N; Katsuragi-Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Daiichi Suntory Biomedical Research Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18327951 104053075 CHEMBL557198 ZINC28524785 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50823902 ClC1=COc2ccccc2C(=O)N1CCCCN1CCC=C(C1)c1ncccn1 InChI=1S/C22H23ClN4O2/c23-20-16-29-19-9-2-1-8-18(19)22(28)27(20)14-4-3-12-26-13-5-7-17(15-26)21-24-10-6-11-25-21/h1-2,6-11,16H,3-5,12-15H2 ZXHBNZSYVCHQIG-UHFFFAOYSA-N 50167870 3-Chloro-4-[4-(5-pyrimidin-2-yl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-4H-benzo[f][1,4]oxazepin-5-one; Compound with fumarate D(2) dopamine receptor Rattus norvegicus 893 ChEMBL 10.1016/j.bmcl.2005.04.059 10.7270/Q21Z456V 15914001 Kamei, K; Maeda, N; Katsuragi-Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Daiichi Suntory Biomedical Research Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15490961 104053076 ZINC28524567 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50823904 ClC1=COc2ccccc2C(=O)N1CCCCN1CCC(=CC1)c1ncccn1 InChI=1S/C22H23ClN4O2/c23-20-16-29-19-7-2-1-6-18(19)22(28)27(20)13-4-3-12-26-14-8-17(9-15-26)21-24-10-5-11-25-21/h1-2,5-8,10-11,16H,3-4,9,12-15H2 OGPYTXGYWMCRCN-UHFFFAOYSA-N 50167872 3-Chloro-4-[4-(4-pyrimidin-2-yl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-4H-benzo[f][1,4]oxazepin-5-one; hydrochloride::CHEMBL558964 D(2) dopamine receptor Rattus norvegicus 494 ChEMBL 10.1016/j.bmcl.2005.04.059 10.7270/Q21Z456V 15914001 Kamei, K; Maeda, N; Katsuragi-Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Daiichi Suntory Biomedical Research Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15490960 104053078 CHEMBL558964 ZINC01892472 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50823905 Cc1ccnc(n1)C1=CN(CCCCN2C(Cl)=COc3ccccc3C2=O)CCC1 InChI=1S/C23H25ClN4O2/c1-17-10-11-25-22(26-17)18-7-6-13-27(15-18)12-4-5-14-28-21(24)16-30-20-9-3-2-8-19(20)23(28)29/h2-3,8-11,15-16H,4-7,12-14H2,1H3 WGTSFBXSLGJRRT-UHFFFAOYSA-N 50167871 3-Chloro-4-{4-[5-(4-methyl-pyrimidin-2-yl)-3,4-dihydro-2H-pyridin-1-yl]-butyl}-4H-benzo[f][1,4]oxazepin-5-one; Compound with fumarate D(2) dopamine receptor Rattus norvegicus 763 ChEMBL 10.1016/j.bmcl.2005.04.059 10.7270/Q21Z456V 15914001 Kamei, K; Maeda, N; Katsuragi-Ogino, R; Koyama, M; Nakajima, M; Tatsuoka, T; Ohno, T; Inoue, T Daiichi Suntory Biomedical Research Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44402781 104053077 ZINC28524883 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50833601 COc1cccc2[C@H](CN(C)CCc3ccc4ccoc4c3)CCCc12 InChI=1S/C23H27NO2/c1-24(13-11-17-9-10-18-12-14-26-23(18)15-17)16-19-5-3-7-21-20(19)6-4-8-22(21)25-2/h4,6,8-10,12,14-15,19H,3,5,7,11,13,16H2,1-2H3/t19-/m0/s1 MHPMXTGKTXJIDI-IBGZPJMESA-N 50057128 (2-Benzofuran-6-yl-ethyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-amine::A-80426::CHEMBL268258 D(2) dopamine receptor Rattus norvegicus 52 ChEMBL 10.1021/jm058225d 10.7270/Q2SF2WZ9 16220969 Morphy, R; Rankovic, Z Organon Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50057128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50057128&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9928332 103953208 CHEMBL268258 ZINC03810797 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828519 Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(cc3)-c3ccccn3)CC2)c1Cl InChI=1S/C26H28Cl2N4O/c27-22-6-5-8-24(25(22)28)32-18-16-31(17-19-32)15-4-3-14-30-26(33)21-11-9-20(10-12-21)23-7-1-2-13-29-23/h1-2,5-13H,3-4,14-19H2,(H,30,33) YJGPWNCHDJDGJR-UHFFFAOYSA-N 50129426 CHEMBL69451::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-4-(pyridin-2-yl)benzamide::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-4-pyridin-2-yl-benzamide D(2) dopamine receptor Rattus norvegicus 57.9 ChEMBL 10.1021/jm040190e 10.7270/Q2474BNF 15916415 Newman, AH; Grundt, P; Nader, MA National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129426&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9826580 104021009 CHEMBL69451 6675 ZINC13534388 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828520 Clc1cccc(N2CCN(C\C=C\CNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl InChI=1S/C28H27Cl2N3O/c29-25-8-5-9-26(27(25)30)33-16-14-32(15-17-33)13-4-3-12-31-28(34)21-10-11-24-22(19-21)18-20-6-1-2-7-23(20)24/h1-11,19H,12-18H2,(H,31,34)/b4-3+ ZCTVOGWWMHRQLN-ONEGZZNKSA-N 50129429 9H-Fluorene-2-carboxylic acid {(E)-4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide::9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide::CHEMBL304605::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)but-2-enyl)-9H-fluorene-2-carboxamide D(2) dopamine receptor Rattus norvegicus 198 ChEMBL 10.1021/jm040190e 10.7270/Q2474BNF 15916415 Newman, AH; Grundt, P; Nader, MA National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129429&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309775 104021012 CHEMBL304605 ZINC13534401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828533 Clc1cccc(N2CCN(C\C=C\CNC(=O)c3ccccc3)CC2)c1Cl InChI=1S/C21H23Cl2N3O/c22-18-9-6-10-19(20(18)23)26-15-13-25(14-16-26)12-5-4-11-24-21(27)17-7-2-1-3-8-17/h1-10H,11-16H2,(H,24,27)/b5-4+ DHOCETPWLQILEE-SNAWJCMRSA-N 50129433 CHEMBL71327::N-{(E)-4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-benzamide::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-benzamide D(2) dopamine receptor Rattus norvegicus 50.10 ChEMBL 10.1021/jm040190e 10.7270/Q2474BNF 15916415 Newman, AH; Grundt, P; Nader, MA National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129433 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129433&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10001256 104021016 CHEMBL71327 ZINC13534412 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828556 Clc1cccc(N2CCN(CCCCNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl InChI=1S/C28H29Cl2N3O/c29-25-8-5-9-26(27(25)30)33-16-14-32(15-17-33)13-4-3-12-31-28(34)21-10-11-24-22(19-21)18-20-6-1-2-7-23(20)24/h1-2,5-11,19H,3-4,12-18H2,(H,31,34) YJPWVCIGSHWNON-UHFFFAOYSA-N 50071959 9H-Fluorene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL300780::N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-9H-fluorene-2-carboxamide D(2) dopamine receptor Rattus norvegicus 911 ChEMBL 10.1021/jm040190e 10.7270/Q2474BNF 15916415 Newman, AH; Grundt, P; Nader, MA National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9891901 103965649 CHEMBL300780 6674 ZINC01545255 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828571 Clc1cccc(N2CCN(CCCCNC(=O)c3ccc(I)cc3)CC2)c1Cl InChI=1S/C21H24Cl2IN3O/c22-18-4-3-5-19(20(18)23)27-14-12-26(13-15-27)11-2-1-10-25-21(28)16-6-8-17(24)9-7-16/h3-9H,1-2,10-15H2,(H,25,28) UKOYDIULRIOVQF-UHFFFAOYSA-N 50129428 CHEMBL302374::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-butyl}-4-iodo-benzamide::Quinoxaline-1-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 87.5 ChEMBL 10.1021/jm040190e 10.7270/Q2474BNF 15916415 Newman, AH; Grundt, P; Nader, MA National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129428 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129428&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309510 104021011 CHEMBL302374 ZINC26288566 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828594 O=C(N[C@H]1CC[C@H](CCN2CCc3cc(ccc3C2)C#N)CC1)c1ccnc2ccccc12 InChI=1S/C28H30N4O/c29-18-21-5-8-23-19-32(16-13-22(23)17-21)15-12-20-6-9-24(10-7-20)31-28(33)26-11-14-30-27-4-2-1-3-25(26)27/h1-5,8,11,14,17,20,24H,6-7,9-10,12-13,15-16,19H2,(H,31,33)/t20-,24- OLWRVVHPJFLNPW-LSNLESRRSA-N 50370572 CHEMBL85606::SB-277011 D(2) dopamine receptor Rattus norvegicus 2820 ChEMBL 10.1021/jm040190e 10.7270/Q2474BNF 15916415 Newman, AH; Grundt, P; Nader, MA National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5311096 160849674 CHEMBL85606 ZINC26574567 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828609 Clc1cccc(N2CCN(CCCCNC(=O)c3cnc4ccccc4n3)CC2)c1Cl InChI=1S/C23H25Cl2N5O/c24-17-6-5-9-21(22(17)25)30-14-12-29(13-15-30)11-4-3-10-26-23(31)20-16-27-18-7-1-2-8-19(18)28-20/h1-2,5-9,16H,3-4,10-15H2,(H,26,31) WKAAYYBBGYEZQQ-UHFFFAOYSA-N 50129432 CHEMBL262724::Quinoxaline-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 109.4 ChEMBL 10.1021/jm040190e 10.7270/Q2474BNF 15916415 Newman, AH; Grundt, P; Nader, MA National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129432 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129432&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309509 104021015 CHEMBL262724 ZINC13534384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828624 Clc1cccc(N2CCN(C\C=C\CNC(=O)c3cccc4Cc5ccccc5-c34)CC2)c1Cl InChI=1S/C28H27Cl2N3O/c29-24-11-6-12-25(27(24)30)33-17-15-32(16-18-33)14-4-3-13-31-28(34)23-10-5-8-21-19-20-7-1-2-9-22(20)26(21)23/h1-12H,13-19H2,(H,31,34)/b4-3+ LFQZHAKGDXWDRR-ONEGZZNKSA-N 50129431 9H-Fluorene-4-carboxylic acid {(E)-4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide::9H-Fluorene-4-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide::CHEMBL69571 D(2) dopamine receptor Rattus norvegicus 106 ChEMBL 10.1021/jm040190e 10.7270/Q2474BNF 15916415 Newman, AH; Grundt, P; Nader, MA National Institute on Drug Abuse-Intramural Research Program http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129431 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129431&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309688 104021014 CHEMBL69571 ZINC13534393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50833902 CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1 ZZJYIKPMDIWRSN-TZBSWOFLSA-N 50366495 (+)butaclamol::CHEMBL1255588 D(2) dopamine receptor Rattus norvegicus 8.9 ChEMBL 10.1021/jm058018d 10.7270/Q28C9X1X 16250647 Minetti, P; Tinti, MO; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Piersanti, G; Bartoccini, F; Tarzia, G Universit£ degli Studi di Urbino Carlo Bo http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37461 160845597 73298 CHEMBL1255588 ZINC01481744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817150 COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC(C1)N2C InChI=1S/C16H22ClN3O2/c1-20-10-3-4-11(20)6-9(5-10)19-16(21)12-7-13(17)14(18)8-15(12)22-2/h7-11H,3-6,18H2,1-2H3,(H,19,21) HTMNINCXKXABOI-UHFFFAOYSA-N 82519 4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)benzamide::BRL 24682::CAS_76272-78-1 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9797313 136350489 ZINC13493298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817151 COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29) DCSUBABJRXZOMT-UHFFFAOYSA-N 50005836 4-Amino-5-chloro-N-{1-[3-(4-fluoro-phenoxy)-propyl]-3-methoxy-piperidin-4-yl}-2-methoxy-benzamide::4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxypiperidin-4-yl)-2-methoxybenzamide::CHEMBL560739::CISAPRIDE::PROPULSID::US10167299, Cisapride::US10800776, Example Cisapride::US9221790, Cisapride::cid_5311047 D(2) dopamine receptor Rattus norvegicus 227 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005836&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2769 103919261 CHEMBL560739 240 C06910 ZINC03830564 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817154 Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C InChI=1S/C18H19N3O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2/h3-6,9-10,13H,7-8,11H2,1-2H3 FELGMEQIXOGIFQ-UHFFFAOYSA-N 85330 CAS_68647::NSC_68647::ONDANSETRON::Ondansetron hydrochloride D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search S87 6W1M 4595 136351430 DB00904 C07325 ZINC00075126 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817155 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 444 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817159 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(NC)nc1OC InChI=1S/C16H26ClN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m1/s1 UXEPXLWCTJUUTO-LLVKDONJSA-N 50070569 5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL38969 D(2) dopamine receptor Rattus norvegicus 17.9 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11810408 103964422 CHEMBL38969 ZINC22928157 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817161 CCOc1nc(NC)c(Br)cc1C(=O)NC1CN(C)CCN(CC)C1 InChI=1S/C17H28BrN5O2/c1-5-23-8-7-22(4)10-12(11-23)20-16(24)13-9-14(18)15(19-3)21-17(13)25-6-2/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24) RLOUIRHFOPUGAP-UHFFFAOYSA-N 50123799 5-Bromo-2-ethoxy-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-6-methylamino-nicotinamide::CHEMBL349146 D(2) dopamine receptor Rattus norvegicus 86.4 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10905751 104016211 CHEMBL349146 ZINC22928196 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817162 CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(NC)nc1OC InChI=1S/C16H26ClN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23) UXEPXLWCTJUUTO-UHFFFAOYSA-N 50070565 5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL39016 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070565 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070565&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44285961 103964418 CHEMBL39016 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817168 CCN1CCN(C)C[C@@H](C1)NC(=O)c1cc(Cl)c(NC)nc1OC InChI=1S/C16H26ClN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m0/s1 UXEPXLWCTJUUTO-NSHDSACASA-N 50070564 5-Chloro-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL432284 D(2) dopamine receptor Rattus norvegicus 202 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070564 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070564&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10937177 103964417 CHEMBL432284 ZINC22928205 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817170 COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN2CCCC1C2 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-14-4-6-20-5-2-3-10(14)9-20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21)/t10?,14-/m0/s1 GZSKEXSLDPEFPT-SBNLOKMTSA-N 50280258 4-Amino-N-(S)-1-aza-bicyclo[3.3.1]non-4-yl-5-chloro-2-methoxy-benzamide::CHEMBL42787 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280258&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44288352 104121962 CHEMBL42787 ZINC13589966 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817184 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(OC)nc1NC InChI=1S/C16H26ClN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)16(24-4)20-14(12)18-2/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m1/s1 JKXXUVHVFJOIIU-LLVKDONJSA-N 50370286 CHEMBL1744067 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11810407 160849388 CHEMBL1744067 ZINC22928201 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817185 CCNc1nc(OC)c(cc1Br)C(=O)NC1CN(C)CCN(CC)C1 InChI=1S/C17H28BrN5O2/c1-5-19-15-14(18)9-13(17(21-15)25-4)16(24)20-12-10-22(3)7-8-23(6-2)11-12/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24) YEQZXAIWXAPBHX-UHFFFAOYSA-N 50070567 5-Bromo-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide::CHEMBL287760 D(2) dopamine receptor Rattus norvegicus 48.10 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070567 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070567&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11732423 103964420 CHEMBL287760 ZINC22928189 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817187 COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC(C1)N2C InChI=1S/C16H22ClN3O2/c1-20-10-3-4-11(20)6-9(5-10)19-16(21)12-7-13(17)14(18)8-15(12)22-2/h7-11H,3-6,18H2,1-2H3,(H,19,21) HTMNINCXKXABOI-UHFFFAOYSA-N 82519 4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)benzamide::BRL 24682::CAS_76272-78-1 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9797313 136350489 ZINC13493298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817188 CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)cc2CCOc12 InChI=1S/C17H24ClN3O2/c1-3-21-6-5-20(2)10-14(11-21)19-17(22)15-9-13(18)8-12-4-7-23-16(12)15/h8-9,14H,3-7,10-11H2,1-2H3,(H,19,22) PJERBUSSZFOMMO-UHFFFAOYSA-N 50123800 5-Chloro-2,3-dihydro-benzofuran-7-carboxylic acid (1-ethyl-4-methyl-[1,4]diazepan-6-yl)-amide::CHEMBL159835 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10936657 104016212 CHEMBL159835 ZINC36107777 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817189 CCN1CCN(C)CC(C1)NC(=O)c1cc(Br)c(nc1OC)N(C)C InChI=1S/C17H28BrN5O2/c1-6-23-8-7-22(4)10-12(11-23)19-16(24)13-9-14(18)15(21(2)3)20-17(13)25-5/h9,12H,6-8,10-11H2,1-5H3,(H,19,24) JHFICXQBISNVSL-UHFFFAOYSA-N 50070568 5-Bromo-6-dimethylamino-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide::CHEMBL291296 D(2) dopamine receptor Rattus norvegicus 75.20 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11047938 103964421 CHEMBL291296 ZINC36093047 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817192 CCN1CCN(CC)CC(C1)NC(=O)c1cc(Cl)c(NC)nc1OC InChI=1S/C17H28ClN5O2/c1-5-22-7-8-23(6-2)11-12(10-22)20-16(24)13-9-14(18)15(19-3)21-17(13)25-4/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24) DHIFXCNCQLXCDU-UHFFFAOYSA-N 50123810 5-Chloro-N-(1,4-diethyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL164324 D(2) dopamine receptor Rattus norvegicus 27.8 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10915622 104016222 CHEMBL164324 ZINC22928215 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817195 CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1 InChI=1S/C21H25ClFN3O3/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27) YPELFRMCRYSPKZ-UHFFFAOYSA-N 94630 4-Amino-5-chloro-2-ethoxy-N-[4-(4-fluoro-benzyl)-morpholin-2-ylmethyl]-benzamide; citrate(AS-4370)::4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)morpholin-2-yl]methyl]benzamide;citric acid::4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid::4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid::4-azanyl-5-chloranyl-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-oxidanylpropane-1,2,3-tricarboxylic acid::CHEMBL60889::MLS001401439::MOSAPRIDE CITRATE::Mosapride::SMR000469200::cid_119583 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=94630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=94630&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 119584 164035874 CHEMBL60889 C13494 ZINC20621758 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817196 COc1cc(N)c(Cl)cc1C(=O)NCCN(C)Cc1ccccc1 InChI=1S/C18H22ClN3O2/c1-22(12-13-6-4-3-5-7-13)9-8-21-18(23)14-10-15(19)16(20)11-17(14)24-2/h3-7,10-11H,8-9,12,20H2,1-2H3,(H,21,23) VAHDNXLTPLSBHW-UHFFFAOYSA-N 50123801 4-Amino-N-[2-(benzyl-methyl-amino)-ethyl]-5-chloro-2-methoxy-benzamide::CHEMBL20748 D(2) dopamine receptor Rattus norvegicus 24.3 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12861897 104016213 CHEMBL20748 ZINC13493299 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817198 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(C)CC1 InChI=1S/C14H20ClN3O2/c1-18-5-3-9(4-6-18)17-14(19)10-7-11(15)12(16)8-13(10)20-2/h7-9H,3-6,16H2,1-2H3,(H,17,19) IYGMGKYKMGATRC-UHFFFAOYSA-N 50123809 4-Amino-5-chloro-2-methoxy-N-(1-methyl-piperidin-4-yl)-benzamide::CHEMBL164425 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44573 104016221 CHEMBL164425 ZINC02000706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817199 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 303 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817202 CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(N)nc1OC InChI=1S/C15H24ClN5O2/c1-4-21-6-5-20(2)8-10(9-21)18-14(22)11-7-12(16)13(17)19-15(11)23-3/h7,10H,4-6,8-9H2,1-3H3,(H2,17,19)(H,18,22) NQAOXCXKUPNSLL-UHFFFAOYSA-N 50070572 6-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide::CHEMBL290959 D(2) dopamine receptor Rattus norvegicus 386 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070572&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10860791 103964425 CHEMBL290959 ZINC36093046 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817203 COc1cc(N)c(Cl)cc1C(=O)N[C@@H]1CN2CCC1CC2 InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-8-19-4-2-9(13)3-5-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20)/t13-/m1/s1 FEROPKNOYKURCJ-CYBMUJFWSA-N 50056419 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-((S)-methoxy)-benzamide::4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(S)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxy-benzamide::CHEMBL28992::ZACOPRIDE,R D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056419 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056419&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604914 103952691 CHEMBL28992 2289 ZINC00003961 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817204 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 13.6 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817206 CCCN1CCN(CC)CC(C1)NC(=O)c1cc(Br)c(NC)nc1OC InChI=1S/C18H30BrN5O2/c1-5-7-24-9-8-23(6-2)11-13(12-24)21-17(25)14-10-15(19)16(20-3)22-18(14)26-4/h10,13H,5-9,11-12H2,1-4H3,(H,20,22)(H,21,25) BCEOCKZGOJADNT-UHFFFAOYSA-N 50123811 5-Bromo-N-(1-ethyl-4-propyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL164000 D(2) dopamine receptor Rattus norvegicus 12.9 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44375753 104016223 CHEMBL164000 ZINC36093091 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817208 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(N)c2CCOc12 InChI=1S/C17H25ClN4O2/c1-3-22-6-5-21(2)9-11(10-22)20-17(23)13-8-14(18)15(19)12-4-7-24-16(12)13/h8,11H,3-7,9-10,19H2,1-2H3,(H,20,23)/t11-/m1/s1 BSCOBUWJGGMKMH-LLVKDONJSA-N 50370287 CHEMBL1744066 D(2) dopamine receptor Rattus norvegicus 637 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11121734 160849389 CHEMBL1744066 ZINC22778610 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817209 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) BVPWJMCABCPUQY-UHFFFAOYSA-N 50132693 4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide(Clebopride)::4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide::CHEMBL325109::Clebopride D(2) dopamine receptor Rattus norvegicus 11.9 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2780 104023670 CHEMBL325109 ZINC00608261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817211 CCN1CCN(C)C[C@@H](C1)NC(=O)c1cc(Br)c(NC)nc1OC InChI=1S/C16H26BrN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m0/s1 FKDXBULKZKICQO-NSHDSACASA-N 50070566 5-Bromo-N-((S)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL40497 D(2) dopamine receptor Rattus norvegicus 122 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10894643 103964419 CHEMBL40497 ZINC19359121 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817213 CCNc1nc(OC)c(cc1Cl)C(=O)NC1CN(C)CCN(CC)C1 InChI=1S/C17H28ClN5O2/c1-5-19-15-14(18)9-13(17(21-15)25-4)16(24)20-12-10-22(3)7-8-23(6-2)11-12/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24) KCVFDLHNTSZQNS-UHFFFAOYSA-N 50070573 5-Chloro-6-ethylamino-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-nicotinamide::CHEMBL38473 D(2) dopamine receptor Rattus norvegicus 76.4 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11003173 103964426 CHEMBL38473 ZINC22928167 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817216 CCN1CCN(CC)CC(C1)NC(=O)c1cc(Br)c(NC)nc1OC InChI=1S/C17H28BrN5O2/c1-5-22-7-8-23(6-2)11-12(10-22)20-16(24)13-9-14(18)15(19-3)21-17(13)25-4/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24) ZSKNMSUICFBPDZ-UHFFFAOYSA-N 50123797 5-Bromo-N-(1,4-diethyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL349050 D(2) dopamine receptor Rattus norvegicus 20.9 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10862569 104016209 CHEMBL349050 ZINC22928220 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817218 CCN1CCN(C)CC(C1)NC(=O)c1cc(Br)c(NC)nc1OC InChI=1S/C16H26BrN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23) FKDXBULKZKICQO-UHFFFAOYSA-N 50070574 5-Bromo-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL40903 D(2) dopamine receptor Rattus norvegicus 23.3 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070574&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21852725 103964427 CHEMBL40903 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817220 CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C16H25ClN4O2/c1-4-21-6-5-20(2)9-11(10-21)19-16(22)12-7-13(17)14(18)8-15(12)23-3/h7-8,11H,4-6,9-10,18H2,1-3H3,(H,19,22) ATMCNNNBGDVDQH-UHFFFAOYSA-N 50069282 4-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-benzamide::CHEMBL346973 D(2) dopamine receptor Rattus norvegicus 127 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11759622 103963390 CHEMBL346973 ZINC36093088 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817221 COc1cc(N)c(Cl)cc1C(=O)NC1CN(C)CCN(Cc2ccccc2)C1 InChI=1S/C21H27ClN4O2/c1-25-8-9-26(12-15-6-4-3-5-7-15)14-16(13-25)24-21(27)17-10-18(22)19(23)11-20(17)28-2/h3-7,10-11,16H,8-9,12-14,23H2,1-2H3,(H,24,27) RJHRGFJWVPMVDG-UHFFFAOYSA-N 50123816 4-Amino-N-(1-benzyl-4-methyl-[1,4]diazepan-6-yl)-5-chloro-2-methoxy-benzamide::CHEMBL163519 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10476255 104016228 CHEMBL163519 ZINC22928149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817223 CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)cc2N(C)C(=O)COc12 InChI=1S/C18H25ClN4O3/c1-4-23-6-5-21(2)9-13(10-23)20-18(25)14-7-12(19)8-15-17(14)26-11-16(24)22(15)3/h7-8,13H,4-6,9-11H2,1-3H3,(H,20,25) MXBRDDSYEXISLW-UHFFFAOYSA-N 50123815 6-Chloro-4-methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-8-carboxylic acid (1-ethyl-4-methyl-[1,4]diazepan-6-yl)-amide::CHEMBL163859 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11783846 104016227 CHEMBL163859 ZINC36107781 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817224 CCN1CCN(C)CC(C1)NC(=O)c1cc(Cl)cn2ccnc12 InChI=1S/C16H22ClN5O/c1-3-21-7-6-20(2)10-13(11-21)19-16(23)14-8-12(17)9-22-5-4-18-15(14)22/h4-5,8-9,13H,3,6-7,10-11H2,1-2H3,(H,19,23) SQCJCBMXZOOJRE-UHFFFAOYSA-N 50123814 6-Chloro-imidazo[1,2-a]pyridine-8-carboxylic acid (1-ethyl-4-methyl-[1,4]diazepan-6-yl)-amide::CHEMBL163800 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10958623 104016226 CHEMBL163800 ZINC36107779 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817229 CCCN1CCN(C)CC(C1)NC(=O)c1cc(Br)c(NC)nc1OC InChI=1S/C17H28BrN5O2/c1-5-6-23-8-7-22(3)10-12(11-23)20-16(24)13-9-14(18)15(19-2)21-17(13)25-4/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24) OGSGEZFHFQQZBX-UHFFFAOYSA-N 50123813 5-Bromo-2-methoxy-6-methylamino-N-(1-methyl-4-propyl-[1,4]diazepan-6-yl)-nicotinamide::CHEMBL351377 D(2) dopamine receptor Rattus norvegicus 47.1 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44375747 104016225 CHEMBL351377 ZINC36093090 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817230 CCOc1nc(NC)c(Cl)cc1C(=O)NC1CN(C)CCN(CC)C1 InChI=1S/C17H28ClN5O2/c1-5-23-8-7-22(4)10-12(11-23)20-16(24)13-9-14(18)15(19-3)21-17(13)25-6-2/h9,12H,5-8,10-11H2,1-4H3,(H,19,21)(H,20,24) ZTPVDGKFYZMLHZ-UHFFFAOYSA-N 50123805 5-Chloro-2-ethoxy-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-6-methylamino-nicotinamide::CHEMBL164360 D(2) dopamine receptor Rattus norvegicus 42.9 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11760413 104016217 CHEMBL164360 ZINC22928175 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817231 COc1cc(N)c(Cl)cc1C(=O)NC[C@@H]1CCN2CCC[C@@H]12 InChI=1S/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-9-10-4-6-20-5-2-3-14(10)20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21)/t10-,14-/m0/s1 GAYSOZKZPOVDSB-HZMBPMFUSA-N 50005833 (exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-pyrrolizin-1-ylmethyl)-benzamide::4-Amino-5-chloro-N-(hexahydro-pyrrolizin-2-ylmethyl)-2-methoxy-benzamide::4-Amino-5-chloro-N-[(1S,7aS)-1-(hexahydro-pyrrolizin-1-yl)methyl]-2-methoxy-benzamide::4-amino-5-chloro-N-[(1S-cis-hexahydro-1H-pyrrolizin-1-yl)-methyl]-2-methoxybenzenecarboxamide::CHEMBL34291::SC-53116::SC49518::SC53116 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005833&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 132337 103919258 CHEMBL34291 238 ZINC03790774 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817234 CNc1nc(OC)c(cc1Cl)C(=O)NC1CN(C)CCN(C)C1 InChI=1S/C15H24ClN5O2/c1-17-13-12(16)7-11(15(19-13)23-4)14(22)18-10-8-20(2)5-6-21(3)9-10/h7,10H,5-6,8-9H2,1-4H3,(H,17,19)(H,18,22) FDLYNYJLMXYFOP-UHFFFAOYSA-N 50123802 5-Chloro-N-(1,4-dimethyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL349595 D(2) dopamine receptor Rattus norvegicus 137 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10925901 104016214 CHEMBL349595 ZINC22928213 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817235 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(NC)cc1OC InChI=1S/C17H27ClN4O2/c1-5-22-7-6-21(3)10-12(11-22)20-17(23)13-8-14(18)15(19-2)9-16(13)24-4/h8-9,12,19H,5-7,10-11H2,1-4H3,(H,20,23)/t12-/m1/s1 WKQKHFBNIGVTEQ-GFCCVEGCSA-N 50070570 5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-4-methylamino-benzamide::CHEMBL40082 D(2) dopamine receptor Rattus norvegicus 34.6 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11002742 103964423 CHEMBL40082 ZINC22452401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817247 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Br)c(NC)nc1OC InChI=1S/C16H26BrN5O2/c1-5-22-7-6-21(3)9-11(10-22)19-15(23)12-8-13(17)14(18-2)20-16(12)24-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,20)(H,19,23)/t11-/m1/s1 FKDXBULKZKICQO-LLVKDONJSA-N 50070571 5-Bromo-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-6-methylamino-nicotinamide::CHEMBL416047 D(2) dopamine receptor Rattus norvegicus 6.88 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9843910 103964424 CHEMBL416047 ZINC22448624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817250 CCN1CCN(C)CC(C1)NC(=O)c1[nH]nc2ccccc12 InChI=1S/C16H23N5O/c1-3-21-9-8-20(2)10-12(11-21)17-16(22)15-13-6-4-5-7-14(13)18-19-15/h4-7,12H,3,8-11H2,1-2H3,(H,17,22)(H,18,19) NACFTHCDWDMEDV-UHFFFAOYSA-N 50123817 1H-Indazole-3-carboxylic acid (1-ethyl-4-methyl-[1,4]diazepan-6-yl)-amide::CHEMBL349048 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10859597 104016229 CHEMBL349048 ZINC36107783 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817251 CCN1CCN(C)CC(C1)NC(=O)c1cnc(NC)nc1OC InChI=1S/C15H26N6O2/c1-5-21-7-6-20(3)9-11(10-21)18-13(22)12-8-17-15(16-2)19-14(12)23-4/h8,11H,5-7,9-10H2,1-4H3,(H,18,22)(H,16,17,19) IYWHZVYLRFYZLP-UHFFFAOYSA-N 50123804 4-Methoxy-2-methylamino-pyrimidine-5-carboxylic acid (1-ethyl-4-methyl-[1,4]diazepan-6-yl)-amide::CHEMBL159972 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50123804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50123804&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10969334 104016216 CHEMBL159972 ZINC36107778 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50817254 CCN1CCN(C)C[C@H](C1)NC(=O)c1cc(Cl)c(NC)cc1OC InChI=1S/C17H27ClN4O2/c1-5-22-7-6-21(3)10-12(11-22)20-17(23)13-8-14(18)15(19-2)9-16(13)24-4/h8-9,12,19H,5-7,10-11H2,1-4H3,(H,20,23)/t12-/m1/s1 WKQKHFBNIGVTEQ-GFCCVEGCSA-N 50070570 5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2-methoxy-4-methylamino-benzamide::CHEMBL40082 D(2) dopamine receptor Rattus norvegicus 34.6 ChEMBL 10.1021/jm020270n 10.7270/Q25H7H06 12593651 Hirokawa, Y; Fujiwara, I; Suzuki, K; Harada, H; Yoshikawa, T; Yoshida, N; Kato, S Dainippon Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070570&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11002742 103964423 CHEMBL40082 ZINC22452401 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828066 CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1 ZZJYIKPMDIWRSN-TZBSWOFLSA-N 50366495 (+)butaclamol::CHEMBL1255588 D(2) dopamine receptor Rattus norvegicus 3.61 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37461 160845597 73298 CHEMBL1255588 ZINC01481744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828073 C(C1Cc2ccccc2C1)N1CCC(Cc2ccccc2)CC1 InChI=1S/C22H27N/c1-2-6-18(7-3-1)14-19-10-12-23(13-11-19)17-20-15-21-8-4-5-9-22(21)16-20/h1-9,19-20H,10-17H2 YMEBJHPCSQTYQZ-UHFFFAOYSA-N 50159014 4-Benzyl-1-indan-2-ylmethyl-piperidine::CHEMBL179145 D(2) dopamine receptor Rattus norvegicus 575 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159014&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11336800 104045614 CHEMBL179145 ZINC13607182 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828077 C(C1COc2ccccc2O1)N1CCC(Cc2ccccc2)CC1 InChI=1S/C21H25NO2/c1-2-6-17(7-3-1)14-18-10-12-22(13-11-18)15-19-16-23-20-8-4-5-9-21(20)24-19/h1-9,18-19H,10-16H2 RSDAEFPWFADGBB-UHFFFAOYSA-N 50159015 4-Benzyl-1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidine::CHEMBL178700 D(2) dopamine receptor Rattus norvegicus 3.61 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159015&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11189143 104045615 CHEMBL178700 ZINC13607212 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828083 COc1cccc2CCC(CN3CCC(Cc4ccccc4)CC3)Cc12 InChI=1S/C24H31NO/c1-26-24-9-5-8-22-11-10-21(17-23(22)24)18-25-14-12-20(13-15-25)16-19-6-3-2-4-7-19/h2-9,20-21H,10-18H2,1H3 PGALYKJJGGBYSX-UHFFFAOYSA-N 50159010 4-Benzyl-1-(8-methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-piperidine::CHEMBL179371 D(2) dopamine receptor Rattus norvegicus 866 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159010&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11440556 104045610 CHEMBL179371 ZINC13607259 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828086 C(C1COc2ccccc2C1)N1CCC(Cc2ccccc2)CC1 InChI=1S/C22H27NO/c1-2-6-18(7-3-1)14-19-10-12-23(13-11-19)16-20-15-21-8-4-5-9-22(21)24-17-20/h1-9,19-20H,10-17H2 SLJXLWDNADHNLA-UHFFFAOYSA-N 50159012 4-Benzyl-1-chroman-3-ylmethyl-piperidine::CHEMBL179373 D(2) dopamine receptor Rattus norvegicus 2493 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159012&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11152527 104045612 CHEMBL179373 ZINC13607198 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828087 COc1ccc2CCC(CN3CCC(Cc4ccccc4)CC3)Cc2c1 InChI=1S/C24H31NO/c1-26-24-10-9-22-8-7-21(16-23(22)17-24)18-25-13-11-20(12-14-25)15-19-5-3-2-4-6-19/h2-6,9-10,17,20-21H,7-8,11-16,18H2,1H3 UHUACPOSAQLXOC-UHFFFAOYSA-N 50159016 4-Benzyl-1-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-piperidine::CHEMBL178680 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159016&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11349674 104045616 CHEMBL178680 ZINC13607254 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828094 C(C1CCc2ccccc2O1)N1CCC(Cc2ccccc2)CC1 InChI=1S/C22H27NO/c1-2-6-18(7-3-1)16-19-12-14-23(15-13-19)17-21-11-10-20-8-4-5-9-22(20)24-21/h1-9,19,21H,10-17H2 XIEPNNMDKPLLAY-UHFFFAOYSA-N 50159024 4-Benzyl-1-chroman-2-ylmethyl-piperidine::CHEMBL178650 D(2) dopamine receptor Rattus norvegicus 3.61 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11220953 104045624 CHEMBL178650 ZINC13607208 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828099 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2.69 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828103 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.42 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828106 C(C1CCc2ccccc2O1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C21H26N2O/c1-2-6-18(7-3-1)16-22-12-14-23(15-13-22)17-20-11-10-19-8-4-5-9-21(19)24-20/h1-9,20H,10-17H2 AJZBPCAHQHCXMX-UHFFFAOYSA-N 50159018 1-Benzyl-4-chroman-2-ylmethyl-piperazine::1-benzyl-4-((3,4-dihydro-2H-chromen-2-yl)methyl)piperazine::CHEMBL179648 D(2) dopamine receptor Rattus norvegicus 3.61 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159018&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10758200 104045618 CHEMBL179648 ZINC22445891 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828110 O=C1C(CN2CCC(Cc3ccccc3)CC2)Cc2ccccc12 InChI=1S/C22H25NO/c24-22-20(15-19-8-4-5-9-21(19)22)16-23-12-10-18(11-13-23)14-17-6-2-1-3-7-17/h1-9,18,20H,10-16H2 QTBRJSBDQGWTQD-UHFFFAOYSA-N 50159019 2-(4-Benzyl-piperidin-1-ylmethyl)-indan-1-one::CHEMBL178924 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11360254 104045619 CHEMBL178924 ZINC13607230 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828120 C(C1COc2ccccc2O1)N1CCC(Cc2ccccc2)CC1 InChI=1S/C21H25NO2/c1-2-6-17(7-3-1)14-18-10-12-22(13-11-18)15-19-16-23-20-8-4-5-9-21(20)24-19/h1-9,18-19H,10-16H2 RSDAEFPWFADGBB-UHFFFAOYSA-N 50159015 4-Benzyl-1-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperidine::CHEMBL178700 D(2) dopamine receptor Rattus norvegicus 447 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159015&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11189143 104045615 CHEMBL178700 ZINC13607212 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828125 C(C1CCCc2ccccc2C1)N1CCC(Cc2ccccc2)CC1 InChI=1S/C24H31N/c1-2-7-20(8-3-1)17-21-13-15-25(16-14-21)19-22-9-6-12-23-10-4-5-11-24(23)18-22/h1-5,7-8,10-11,21-22H,6,9,12-19H2 BPMOOEDLDRJAKW-UHFFFAOYSA-N 50159017 4-Benzyl-1-(6,7,8,9-tetrahydro-5H-benzocyclohepten-6-ylmethyl)-piperidine::CHEMBL179808 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159017&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11326158 104045617 CHEMBL179808 ZINC13607193 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50828133 C(CN1CCC(Cc2ccccc2)CC1)Cc1ccccc1 InChI=1S/C21H27N/c1-3-8-19(9-4-1)12-7-15-22-16-13-21(14-17-22)18-20-10-5-2-6-11-20/h1-6,8-11,21H,7,12-18H2 OEOKSYGSLJBPFM-UHFFFAOYSA-N 50159011 4-Benzyl-1-(4-phenyl-butyl)-piperidine::CHEMBL178153 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm049433t 10.7270/Q2JH3MZW 15634021 Costantino, L; Gandolfi, F; Sorbi, C; Franchini, S; Prezzavento, O; Vittorio, F; Ronsisvalle, G; Leonardi, A; Poggesi, E; Brasili, L Universit£ di Modena and Reggio Emilia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50159011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50159011&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23294399 104045611 CHEMBL178153 ZINC13607180 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50819374 CN[C@@H]1Cc2cccc3[nH]c(=O)n(C1)c23 InChI=1S/C11H13N3O/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9/h2-4,8,12H,5-6H2,1H3,(H,13,15)/t8-/m1/s1 RKZSNTNMEFVBDT-MRVPVSSYSA-N 50056443 (R)-5-Methylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one::CHEMBL419792::PNU-95666E D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm030505a 10.7270/Q24B3225 15239663 Cowart, M; Latshaw, SP; Bhatia, P; Daanen, JF; Rohde, J; Nelson, SL; Patel, M; Kolasa, T; Nakane, M; Uchic, ME; Miller, LN; Terranova, MA; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Martino, BR; Lynch, JJ; Sullivan, JP; Hsieh, GC; Moreland, RB; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50056443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50056443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9818479 103952699 CHEMBL419792 3949 ZINC03960633 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50819376 Fc1ccc2[nH]c(CN3CCN(CC3)c3ccccn3)cc2c1 InChI=1S/C18H19FN4/c19-15-4-5-17-14(11-15)12-16(21-17)13-22-7-9-23(10-8-22)18-3-1-2-6-20-18/h1-6,11-12,21H,7-10,13H2 PQOIDBZLMJMYCD-UHFFFAOYSA-N 50145073 5-Fluoro-2-(4-pyridin-2-yl-piperazin-1-ylmethyl)-1H-indole::CHEMBL77395::CP-226269 D(2) dopamine receptor Rattus norvegicus 527 ChEMBL 10.1021/jm030505a 10.7270/Q24B3225 15239663 Cowart, M; Latshaw, SP; Bhatia, P; Daanen, JF; Rohde, J; Nelson, SL; Patel, M; Kolasa, T; Nakane, M; Uchic, ME; Miller, LN; Terranova, MA; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Martino, BR; Lynch, JJ; Sullivan, JP; Hsieh, GC; Moreland, RB; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50145073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50145073&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9796720 104034001 CHEMBL77395 973 ZINC13560675 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50819383 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm030505a 10.7270/Q24B3225 15239663 Cowart, M; Latshaw, SP; Bhatia, P; Daanen, JF; Rohde, J; Nelson, SL; Patel, M; Kolasa, T; Nakane, M; Uchic, ME; Miller, LN; Terranova, MA; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Martino, BR; Lynch, JJ; Sullivan, JP; Hsieh, GC; Moreland, RB; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50819387 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm030505a 10.7270/Q24B3225 15239663 Cowart, M; Latshaw, SP; Bhatia, P; Daanen, JF; Rohde, J; Nelson, SL; Patel, M; Kolasa, T; Nakane, M; Uchic, ME; Miller, LN; Terranova, MA; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Martino, BR; Lynch, JJ; Sullivan, JP; Hsieh, GC; Moreland, RB; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50819391 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 0.4 ChEMBL 10.1021/jm030505a 10.7270/Q24B3225 15239663 Cowart, M; Latshaw, SP; Bhatia, P; Daanen, JF; Rohde, J; Nelson, SL; Patel, M; Kolasa, T; Nakane, M; Uchic, ME; Miller, LN; Terranova, MA; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Martino, BR; Lynch, JJ; Sullivan, JP; Hsieh, GC; Moreland, RB; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50819398 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 8 ChEMBL 10.1021/jm030505a 10.7270/Q24B3225 15239663 Cowart, M; Latshaw, SP; Bhatia, P; Daanen, JF; Rohde, J; Nelson, SL; Patel, M; Kolasa, T; Nakane, M; Uchic, ME; Miller, LN; Terranova, MA; Chang, R; Donnelly-Roberts, DL; Namovic, MT; Hollingsworth, PR; Martino, BR; Lynch, JJ; Sullivan, JP; Hsieh, GC; Moreland, RB; Brioni, JD; Stewart, AO Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50845298 CC(C)N1CCC(CC1)C(CN1CCN(CCCc2ccccc2-c2cccc(F)c2)CC1)c1ccc(F)cc1 InChI=1S/C35H45F2N3/c1-27(2)40-19-16-30(17-20-40)35(29-12-14-32(36)15-13-29)26-39-23-21-38(22-24-39)18-6-9-28-7-3-4-11-34(28)31-8-5-10-33(37)25-31/h3-5,7-8,10-15,25,27,30,35H,6,9,16-24,26H2,1-2H3 BXMQVSMCTWXOEI-UHFFFAOYSA-N 50203994 (+/-)-1-[3-(30-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]piperazine trihydrochloride::CHEMBL557585 D(2) dopamine receptor Rattus norvegicus 805 ChEMBL 10.1016/j.bmc.2007.01.019 10.7270/Q20P10TN 17267226 Nozawa, D; Okubo, T; Ishii, T; Takamori, K; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203994&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423381 104082935 CHEMBL557585 ZINC28645983 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50845299 CC(C)N1CCC(CC1)C(CN1CCN(CCCc2cccc(F)c2-c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C35H45F2N3/c1-27(2)40-20-17-29(18-21-40)33(28-13-15-32(36)16-14-28)26-39-24-22-38(23-25-39)19-7-11-31-10-6-12-34(37)35(31)30-8-4-3-5-9-30/h3-6,8-10,12-16,27,29,33H,7,11,17-26H2,1-2H3 QZSJYHCBUZIVJV-UHFFFAOYSA-N 50203995 (+/-)-1-[3-(6-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]piperazine trihydrochloride::CHEMBL537873 D(2) dopamine receptor Rattus norvegicus 482 ChEMBL 10.1016/j.bmc.2007.01.019 10.7270/Q20P10TN 17267226 Nozawa, D; Okubo, T; Ishii, T; Takamori, K; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203995&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423363 104082936 CHEMBL537873 ZINC28645923 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50845308 CC(C)N1CCC(CC1)C(CN1CCN(CCCc2ccccc2-c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C35H46FN3/c1-28(2)39-21-18-32(19-22-39)35(31-14-16-33(36)17-15-31)27-38-25-23-37(24-26-38)20-8-12-30-11-6-7-13-34(30)29-9-4-3-5-10-29/h3-7,9-11,13-17,28,32,35H,8,12,18-27H2,1-2H3 PSEZXKUUBYWUDL-UHFFFAOYSA-N 50203991 (+/-)-1-(3-biphenyl-2-ylpropyl)-4-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]piperazine tri hydrochloride::CHEMBL541897 D(2) dopamine receptor Rattus norvegicus 423 ChEMBL 10.1016/j.bmc.2007.01.019 10.7270/Q20P10TN 17267226 Nozawa, D; Okubo, T; Ishii, T; Takamori, K; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203991&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423362 104082932 CHEMBL541897 ZINC28645916 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50845317 CC(C)N1CCC(CC1)C(CN1CCN(CCCc2c(F)cccc2-c2ccccc2)CC1)c1ccc(F)cc1 InChI=1S/C35H45F2N3/c1-27(2)40-20-17-30(18-21-40)34(29-13-15-31(36)16-14-29)26-39-24-22-38(23-25-39)19-7-11-33-32(10-6-12-35(33)37)28-8-4-3-5-9-28/h3-6,8-10,12-16,27,30,34H,7,11,17-26H2,1-2H3 DHUKBDYVZDFTNL-UHFFFAOYSA-N 50203996 (+/-)-1-[3-(3-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]piperazine trihydrochloride::CHEMBL536747 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2007.01.019 10.7270/Q20P10TN 17267226 Nozawa, D; Okubo, T; Ishii, T; Takamori, K; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423377 104082937 CHEMBL536747 ZINC28645970 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50845321 COc1ccc2ccccc2c1CCCCN1CCN(CC(C2CCN(CC2)C(C)C)c2ccc(F)cc2)CC1 InChI=1S/C35H48FN3O/c1-27(2)39-20-17-30(18-21-39)34(29-11-14-31(36)15-12-29)26-38-24-22-37(23-25-38)19-7-6-10-33-32-9-5-4-8-28(32)13-16-35(33)40-3/h4-5,8-9,11-16,27,30,34H,6-7,10,17-26H2,1-3H3 YQAIQMBVUVSWQU-UHFFFAOYSA-N 50203993 (+/-)-1-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]-4-[4-(2-methoxy-1-naphthyl)butyl]piperazine trihydrochloride::CHEMBL558789 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2007.01.019 10.7270/Q20P10TN 17267226 Nozawa, D; Okubo, T; Ishii, T; Takamori, K; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203993&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423360 104082934 CHEMBL558789 ZINC28645909 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50845322 CC(C)N1CCC(CC1)C(CN1CCN(CCCc2ccccc2-c2ccc(F)cc2)CC1)c1ccc(F)cc1 InChI=1S/C35H45F2N3/c1-27(2)40-20-17-31(18-21-40)35(30-11-15-33(37)16-12-30)26-39-24-22-38(23-25-39)19-5-7-28-6-3-4-8-34(28)29-9-13-32(36)14-10-29/h3-4,6,8-16,27,31,35H,5,7,17-26H2,1-2H3 MRONRUQTGKMEGH-UHFFFAOYSA-N 50203992 (+/-)-1-[3-(40-fluorobiphenyl-2-yl)propyl]-4-[2-(4-fluorophenyl)-2-(1-isopropylpiperidin-4-yl)ethyl]piperazine trihydrochloride::CHEMBL536977 D(2) dopamine receptor Rattus norvegicus 820 ChEMBL 10.1016/j.bmc.2007.01.019 10.7270/Q20P10TN 17267226 Nozawa, D; Okubo, T; Ishii, T; Takamori, K; Chaki, S; Okuyama, S; Nakazato, A Taisho Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203992&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44423383 104082933 CHEMBL536977 ZINC28645990 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50840705 CCCN1Cc2ccccc2C2C1COc1cc(O)c(O)cc21 InChI=1S/C19H21NO3/c1-2-7-20-10-12-5-3-4-6-13(12)19-14-8-16(21)17(22)9-18(14)23-11-15(19)20/h3-6,8-9,15,19,21-22H,2,7,10-11H2,1H3 ZFTCHNBVJNLSJT-UHFFFAOYSA-N 50370760 CHEMBL1203924 D(2) dopamine receptor Rattus norvegicus 1600 ChEMBL 10.1021/jm0604979 10.7270/Q25T3M92 17154515 Cueva, JP; Giorgioni, G; Grubbs, RA; Chemel, BR; Watts, VJ; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370760&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44417647 160849861 CHEMBL1203924 ZINC36089508 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50840712 Oc1cc2OC[C@@H]3NCc4ccccc4[C@H]3c2cc1O InChI=1S/C16H15NO3/c18-13-5-11-15(6-14(13)19)20-8-12-16(11)10-4-2-1-3-9(10)7-17-12/h1-6,12,16-19H,7-8H2/t12-,16-/m0/s1 QDUNOUQOKOYLCH-LRDDRELGSA-N 50200352 (6aS,12bR)-(-)-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline::CHEMBL384046 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm0604979 10.7270/Q25T3M92 17154515 Cueva, JP; Giorgioni, G; Grubbs, RA; Chemel, BR; Watts, VJ; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24878061 104080716 CHEMBL384046 ZINC34801101 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50840716 Oc1cc2OC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C16H15NO3/c18-13-5-11-15(6-14(13)19)20-8-12-16(11)10-4-2-1-3-9(10)7-17-12/h1-6,12,16-19H,7-8H2/t12-,16-/m1/s1 QDUNOUQOKOYLCH-MLGOLLRUSA-N 50200353 (6aR,12bS)-(+)-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline::CHEMBL387250 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm0604979 10.7270/Q25T3M92 17154515 Cueva, JP; Giorgioni, G; Grubbs, RA; Chemel, BR; Watts, VJ; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200353&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15981509 104080717 CHEMBL387250 ZINC34801104 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50840723 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 5 ChEMBL 10.1021/jm0604979 10.7270/Q25T3M92 17154515 Cueva, JP; Giorgioni, G; Grubbs, RA; Chemel, BR; Watts, VJ; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50840729 Oc1cc2OCC3NCc4ccccc4C3c2cc1O InChI=1S/C16H15NO3/c18-13-5-11-15(6-14(13)19)20-8-12-16(11)10-4-2-1-3-9(10)7-17-12/h1-6,12,16-19H,7-8H2 QDUNOUQOKOYLCH-UHFFFAOYSA-N 50200351 (+/-)-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline::CHEMBL217299 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm0604979 10.7270/Q25T3M92 17154515 Cueva, JP; Giorgioni, G; Grubbs, RA; Chemel, BR; Watts, VJ; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50200351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50200351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25142456 104080715 CHEMBL217299 ZINC34801104 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50840730 CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole D(2) dopamine receptor Rattus norvegicus 9 ChEMBL 10.1021/jm0604979 10.7270/Q25T3M92 17154515 Cueva, JP; Giorgioni, G; Grubbs, RA; Chemel, BR; Watts, VJ; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84637&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 136350737 CHEMBL240773 ZINC25724686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50840741 Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1 BGOQGUHWXBGXJW-RHSMWYFYSA-N 50010686 (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium::(6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX)::5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol::CHEMBL25856::dihydrexidine D(2) dopamine receptor Rattus norvegicus 70 ChEMBL 10.1021/jm0604979 10.7270/Q25T3M92 17154515 Cueva, JP; Giorgioni, G; Grubbs, RA; Chemel, BR; Watts, VJ; Nichols, DE Purdue University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010686&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603820 103923432 CHEMBL25856 ZINC25758512 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853045 Oc1cc2CCNC3Cc4ccccc4Cc(c1)c23 InChI=1S/C17H17NO/c19-15-8-13-5-6-18-16-10-12-4-2-1-3-11(12)7-14(9-15)17(13)16/h1-4,8-9,16,18-19H,5-7,10H2 ZCATUTKNMGBMKU-UHFFFAOYSA-N 50202286 1,2,3,7,12,12a-hexahydro-1-aza-pleiaden-5-ol::CHEMBL253530 D(2) dopamine receptor Rattus norvegicus 20000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448059 104081863 CHEMBL253530 ZINC29041725 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853046 CN1CCc2ccc3[C@H](N)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H18N2/c1-20-8-7-10-5-6-13-17-15-11(9-14(20)16(10)17)3-2-4-12(15)18(13)19/h2-6,14,18H,7-9,19H2,1H3/t14-,18-/m1/s1 DAKGDRVNCPHAPY-RDTXWAMCSA-N 50087035 (1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::CHEMBL281048 D(2) dopamine receptor Rattus norvegicus 260 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087035&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10706626 103986145 CHEMBL281048 ZINC13806920 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853048 COc1cc-2c(C[C@@H]3NCCc4cc(O)c(OC)c-2c34)cc1O InChI=1S/C18H19NO4/c1-22-15-8-11-10(7-13(15)20)5-12-16-9(3-4-19-12)6-14(21)18(23-2)17(11)16/h6-8,12,19-21H,3-5H2,1-2H3/t12-/m0/s1 KYVJVURXKAZJRK-LBPRGKRZSA-N 50292446 (S)-1,10-Dimethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol::CHEMBL487388::Laurolitsine::[(+)-norboldine]::laurolistine D(2) dopamine receptor Rattus norvegicus 6800 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 22179 104133997 66557 CHEMBL487388 C16984 ZINC02559362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853050 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(OC(C)=O)c-31 InChI=1S/C21H23NO2/c1-3-11-22-12-10-15-6-4-8-17-20(15)18(22)13-16-7-5-9-19(21(16)17)24-14(2)23/h4-9,18H,3,10-13H2,1-2H3/t18-/m1/s1 DDXVSTOHMBOXGN-GOSISDBHSA-N 50202291 Acetic acid (R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester::CHEMBL255229 D(2) dopamine receptor Rattus norvegicus 72 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202291&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11336218 104081868 CHEMBL255229 ZINC13985687 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853054 CCCN1CCc2cc(OC)c(OC)c3Cc4ccccc4CC1c23 InChI=1S/C22H27NO2/c1-4-10-23-11-9-17-14-20(24-2)22(25-3)18-12-15-7-5-6-8-16(15)13-19(23)21(17)18/h5-8,14,19H,4,9-13H2,1-3H3 NKKUZNDFNOKSJF-UHFFFAOYSA-N 50202293 5,6-dimethoxy-1-propyl-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene::CHEMBL404241 D(2) dopamine receptor Rattus norvegicus 14000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448069 104081870 CHEMBL404241 ZINC29041764 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853055 COc1cc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(-c2cc1OC)c34 InChI=1S/C21H25NO4/c1-22-7-6-12-9-18(25-4)21(26-5)20-14-11-17(24-3)16(23-2)10-13(14)8-15(22)19(12)20/h9-11,15H,6-8H2,1-5H3/t15-/m0/s1 RUZIUYOSRDWYQF-HNNXBMFYSA-N 50197829 (S)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL228082::GLAUCINE::glaucine fumarate D(2) dopamine receptor Rattus norvegicus 2800 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197829&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 08V 7N54 16754 104079014 CHEMBL228082 C09446 ZINC00607911 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853056 CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H23NO3/c1-3-7-21-8-6-13-9-14(24-2)11-15-18(13)16(21)10-12-4-5-17(22)20(23)19(12)15/h4-5,9,11,16,22-23H,3,6-8,10H2,1-2H3/t16-/m1/s1 WNNMRMNAGNMVEW-MRXNPFEDSA-N 50010692 (R)-(-)-2-methoxy-N-npropylnorapomorphine::(R)-2-methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53294 D(2) dopamine receptor Rattus norvegicus 0.17 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130907 103923438 CHEMBL53294 ZINC00011666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853057 CCCN1CCc2cc(SC)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H23NO2S/c1-3-7-21-8-6-13-9-14(24-2)11-15-18(13)16(21)10-12-4-5-17(22)20(23)19(12)15/h4-5,9,11,16,22-23H,3,6-8,10H2,1-2H3/t16-/m1/s1 XVYZJYSSEQUGFX-MRXNPFEDSA-N 50202294 (R)-2-methylsulfanyl-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL258371 D(2) dopamine receptor Rattus norvegicus 3.7 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202294&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11688708 104081871 CHEMBL258371 ZINC29041611 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853058 CN1CCc2cc(O)cc3Oc4ccccc4CC1c23 InChI=1S/C17H17NO2/c1-18-7-6-12-8-13(19)10-16-17(12)14(18)9-11-4-2-3-5-15(11)20-16/h2-5,8,10,14,19H,6-7,9H2,1H3 BBDMAMMSMIPUOS-UHFFFAOYSA-N 50202296 1-Methyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-5-ol::CHEMBL155208 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202296&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333195 104081873 CHEMBL155208 ZINC13805084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853062 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2O)c-31 InChI=1S/C24H23NO/c1-15-6-3-11-21(26)22(15)18-9-5-8-17-14-20-24-16(12-13-25(20)2)7-4-10-19(24)23(17)18/h3-11,20,26H,12-14H2,1-2H3/t20-/m1/s1 QQYBSVWWEQVBIX-HXUWFJFHSA-N 50098544 (6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::(6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::3-methyl-2-((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::CHEMBL26907 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593348 103995557 CHEMBL26907 ZINC13531273 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853064 CCCN1CCc2cc(Br)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H20BrNO2/c1-2-6-21-7-5-12-8-13(20)10-14-17(12)15(21)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,22-23H,2,5-7,9H2,1H3/t15-/m1/s1 NZSGOEUDQMTJJY-OAHLLOKOSA-N 50013059 (R)-2-bromo-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Bromo-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL322574 D(2) dopamine receptor Rattus norvegicus 0.89 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013059&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 25053021 103925282 CHEMBL322574 ZINC26841496 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853065 COc1ccc2C[C@@H]3N(C)CCc4ccc(OC)c(Oc2c1O)c34 InChI=1S/C19H21NO4/c1-20-9-8-11-4-7-15(23-3)19-16(11)13(20)10-12-5-6-14(22-2)17(21)18(12)24-19/h4-7,13,21H,8-10H2,1-3H3/t13-/m0/s1 IJSPIEAJJJWASA-ZDUSSCGKSA-N 50292458 CHEMBL510777::Sarcocapnidine D(2) dopamine receptor Rattus norvegicus 2000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11099480 104134009 CHEMBL510777 ZINC14690984 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853067 O=C1c2ccccc2-c2c3OCOc3cc3ccnc1c23 InChI=1S/C17H9NO3/c19-16-11-4-2-1-3-10(11)14-13-9(5-6-18-15(13)16)7-12-17(14)21-8-20-12/h1-7H,8H2 MUMCCPUVOAUBAN-UHFFFAOYSA-N 50202301 CHEMBL37736::Liriodenine::hiriodenine D(2) dopamine receptor Rattus norvegicus 59000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202301&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10144 104081878 70649 CHEMBL37736 C09567 ZINC00006256 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853078 COc1cc2CCN(C)C3Cc4ccc(O)c(O)c4-c(c1OC)c23 InChI=1S/C19H21NO4/c1-20-7-6-11-9-14(23-2)19(24-3)17-15(11)12(20)8-10-4-5-13(21)18(22)16(10)17/h4-5,9,12,21-22H,6-8H2,1-3H3 FNHRMNVLZGCBIE-UHFFFAOYSA-N 50202307 1,2-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL257957 D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202307&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23930365 104081884 CHEMBL257957 ZINC14725306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853081 CN1CCc2ccc3c4-c5c(cccc5C[C@@H]1c24)[C@]3(C)O InChI=1S/C19H19NO/c1-19(21)13-5-3-4-12-10-15-17-11(8-9-20(15)2)6-7-14(19)18(17)16(12)13/h3-7,15,21H,8-10H2,1-2H3/t15-,19+/m1/s1 UIYKUTOPDMMXAX-BEFAXECRSA-N 50087031 (1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::1,6-Dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::CHEMBL417473 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087031&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10707685 103986141 CHEMBL417473 ZINC13806915 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853082 CN1CCc2cc(O)c(O)c3Cc4ccccc4CC1c23 InChI=1S/C18H19NO2/c1-19-7-6-13-10-16(20)18(21)14-8-11-4-2-3-5-12(11)9-15(19)17(13)14/h2-5,10,15,20-21H,6-9H2,1H3 RGAYRBZKAXNILT-UHFFFAOYSA-N 50202308 1-methyl-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene-5,6-diol::CHEMBL253738 D(2) dopamine receptor Rattus norvegicus 15000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202308&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10265732 104081885 CHEMBL253738 ZINC29041742 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853083 CO[C@@]1(C)c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45 InChI=1S/C20H21NO/c1-20(22-3)14-6-4-5-13-11-16-18-12(9-10-21(16)2)7-8-15(20)19(18)17(13)14/h4-8,16H,9-11H2,1-3H3/t16-,20+/m1/s1 JVZCJQBRRXZMQR-UZLBHIALSA-N 50087029 (1S,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::(6S,10aR)-6-methoxy-1,6-dimethyl-1,2,3,6,10,10a-hexahydrofluoreno[3,4,5-defg]quinoline::1-Methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL281923 D(2) dopamine receptor Rattus norvegicus 71 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087029&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10379532 103986139 CHEMBL281923 ZINC13806934 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853087 CCCN1CCc2cc(N)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H22N2O2/c1-2-6-21-7-5-12-8-13(20)10-14-17(12)15(21)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,22-23H,2,5-7,9,20H2,1H3/t15-/m1/s1 GBWRVNBURCRHGS-OAHLLOKOSA-N 50013060 (R)-2-amino-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Amino-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL107041 D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013060&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14728697 103925283 CHEMBL107041 ZINC26849692 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853088 COc1cc2CCN(C)C3Cc4ccccc4Cc(c1OC)c23 InChI=1S/C20H23NO2/c1-21-9-8-15-12-18(22-2)20(23-3)16-10-13-6-4-5-7-14(13)11-17(21)19(15)16/h4-7,12,17H,8-11H2,1-3H3 ATYFXYUBZIBMKL-UHFFFAOYSA-N 50202310 5,6-dimethoxy-1-methyl-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene::CHEMBL404240 D(2) dopamine receptor Rattus norvegicus >20000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202310&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448067 104081887 CHEMBL404240 ZINC29041756 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853091 COc1cc2C[C@@H]3N(C)CCc4c(I)c(O)c(OC)c(-c2cc1OC)c34 InChI=1S/C20H22INO4/c1-22-6-5-11-16-13(22)7-10-8-14(24-2)15(25-3)9-12(10)17(16)20(26-4)19(23)18(11)21/h8-9,13,23H,5-7H2,1-4H3/t13-/m0/s1 BJVUGLIHJZKICR-ZDUSSCGKSA-N 50202311 (S)-3-iodo-1,9,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol::CHEMBL401690 D(2) dopamine receptor Rattus norvegicus 830 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202311&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11619691 104081888 CHEMBL401690 ZINC29041654 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853092 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2C#N)c-31 InChI=1S/C25H22N2/c1-16-6-3-9-19(15-26)23(16)20-10-5-8-18-14-22-25-17(12-13-27(22)2)7-4-11-21(25)24(18)20/h3-11,22H,12-14H2,1-2H3/t22-/m1/s1 APEZAWGOFKUHCA-JOCHJYFZSA-N 50098549 (6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::(6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::3-Methyl-2-((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::CHEMBL28056 D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11725453 103995562 CHEMBL28056 ZINC01493886 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853093 CN1CCc2cccc-3c2[C@H]1Cc1ccc(Br)c(O)c-31 InChI=1S/C17H16BrNO/c1-19-8-7-10-3-2-4-12-15(10)14(19)9-11-5-6-13(18)17(20)16(11)12/h2-6,14,20H,7-9H2,1H3/t14-/m1/s1 LOSIOYLXOVSGIE-CQSZACIVSA-N 50016011 (R)-10-bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::10-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL155884 D(2) dopamine receptor Rattus norvegicus 660 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016011&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44370644 103927692 CHEMBL155884 ZINC27656785 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853094 Oc1ccc-2c(C[C@H]3NCCc4cc5OCOc5c-2c34)c1 InChI=1S/C17H15NO3/c19-11-1-2-12-10(5-11)6-13-15-9(3-4-18-13)7-14-17(16(12)15)21-8-20-14/h1-2,5,7,13,18-19H,3-4,6,8H2/t13-/m1/s1 LTSPCGWFQLHECP-CYBMUJFWSA-N 50202287 (R)-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-10-ol::Anolobine::CHEMBL257746 D(2) dopamine receptor Rattus norvegicus 15000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 164710 104081864 CHEMBL257746 C09338 ZINC00898393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853095 COc1cc2CCN(C)C3Cc4ccccc4Cc(c1)c23 InChI=1S/C19H21NO/c1-20-8-7-15-10-17(21-2)11-16-9-13-5-3-4-6-14(13)12-18(20)19(15)16/h3-6,10-11,18H,7-9,12H2,1-2H3 DPVDARXFSLMHTA-UHFFFAOYSA-N 50202314 5-methoxy-1-methyl-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene::CHEMBL402735 D(2) dopamine receptor Rattus norvegicus 8200 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448060 104081891 CHEMBL402735 ZINC29041728 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853096 COc1cc2C[C@@H]3N(C)CCc4ccc(O)c(Oc2cc1OC)c34 InChI=1S/C19H21NO4/c1-20-7-6-11-4-5-14(21)19-18(11)13(20)8-12-9-16(22-2)17(23-3)10-15(12)24-19/h4-5,9-10,13,21H,6-8H2,1-3H3/t13-/m0/s1 ITGZZZYNPULRNZ-ZDUSSCGKSA-N 50292456 CHEMBL455633::Cularidine D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 442203 104134007 CHEMBL455633 C09400 ZINC29041595 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853098 COc1c(O)c2-c3ccccc3CC3N(C)CCc(c1OC)c23 InChI=1S/C19H21NO3/c1-20-9-8-13-15-14(20)10-11-6-4-5-7-12(11)16(15)17(21)19(23-3)18(13)22-2/h4-7,14,21H,8-10H2,1-3H3 BIIHCZLUQVXIQY-UHFFFAOYSA-N 50202313 2,3-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol::CHEMBL257747 D(2) dopamine receptor Rattus norvegicus 2800 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202313&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14140118 104081890 CHEMBL257747 ZINC14775228 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853102 CN1CCc2ccc3[C@H](O)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H17NO/c1-19-8-7-10-5-6-13-17-15-11(9-14(19)16(10)17)3-2-4-12(15)18(13)20/h2-6,14,18,20H,7-9H2,1H3/t14-,18-/m1/s1 HIYLSOSERAQOHL-RDTXWAMCSA-N 50087028 (1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::CHEMBL26751 D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087028&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10730269 103986138 CHEMBL26751 ZINC13806907 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853104 CCN1CCc2cccc3Oc4ccc(O)cc4CC1c23 InChI=1S/C18H19NO2/c1-2-19-9-8-12-4-3-5-17-18(12)15(19)11-13-10-14(20)6-7-16(13)21-17/h3-7,10,15,20H,2,8-9,11H2,1H3 WDBUJQKFRINDKP-UHFFFAOYSA-N 50202316 1-ethyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-10-ol::CHEMBL154468 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202316&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10660476 104081893 CHEMBL154468 ZINC13805117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853105 CCN1CCc2cc(O)cc3Cc4ccccc4CC1c23 InChI=1S/C19H21NO/c1-2-20-8-7-15-10-17(21)11-16-9-13-5-3-4-6-14(13)12-18(20)19(15)16/h3-6,10-11,18,21H,2,7-9,12H2,1H3 XNGLEHIRBWHLJU-UHFFFAOYSA-N 50202305 1-ethyl-1,2,3,7,12,12a-hexahydro-1-aza-pleiaden-5-ol::CHEMBL253529 D(2) dopamine receptor Rattus norvegicus 15000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202305&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448057 104081882 CHEMBL253529 ZINC29041718 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853109 CCCN1CCc2cc(OC)cc3Cc4ccccc4CC1c23 InChI=1S/C21H25NO/c1-3-9-22-10-8-17-12-19(23-2)13-18-11-15-6-4-5-7-16(15)14-20(22)21(17)18/h4-7,12-13,20H,3,8-11,14H2,1-2H3 TZROCAJLBPLZRY-UHFFFAOYSA-N 50202317 5-methoxy-1-propyl-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene::CHEMBL253737 D(2) dopamine receptor Rattus norvegicus 14000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202317&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448062 104081894 CHEMBL253737 ZINC29041735 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853110 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853115 COc1cc-2c(C[C@@H]3N(C)CCc4cc(O)c(OC)c-2c34)cc1O InChI=1S/C19H21NO4/c1-20-5-4-10-7-15(22)19(24-3)18-12-9-16(23-2)14(21)8-11(12)6-13(20)17(10)18/h7-9,13,21-22H,4-6H2,1-3H3/t13-/m0/s1 LZJRNLRASBVRRX-ZDUSSCGKSA-N 50202318 (+)-boldine::(S)-(+)-Boldine::(S)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol::CHEMBL388342::boldine::cid_10154::cid_248507 D(2) dopamine receptor Rattus norvegicus 370 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202318&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10154 104081895 CHEMBL388342 C09365 ZINC00135449 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853120 CCN1CCc2cc(OC)cc3Cc4ccccc4CC1c23 InChI=1S/C20H23NO/c1-3-21-9-8-16-11-18(22-2)12-17-10-14-6-4-5-7-15(14)13-19(21)20(16)17/h4-7,11-12,19H,3,8-10,13H2,1-2H3 CCZKGWXXNVIVTK-UHFFFAOYSA-N 50202323 1-ethyl-5-methoxy-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene::CHEMBL253736 D(2) dopamine receptor Rattus norvegicus 9700 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448061 104081900 CHEMBL253736 ZINC29041732 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853121 C1Oc2cc3CCN[C@@H]4Cc5ccccc5-c(c2O1)c34 InChI=1S/C17H15NO2/c1-2-4-12-10(3-1)7-13-15-11(5-6-18-13)8-14-17(16(12)15)20-9-19-14/h1-4,8,13,18H,5-7,9H2/t13-/m1/s1 VZTUKBKUWSHDFM-CYBMUJFWSA-N 50202322 (-)-anonaine::(R)-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline::6,7,7a,8-Tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline::Anonaine::CHEMBL401798 D(2) dopamine receptor Rattus norvegicus 19000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202322&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 160597 104081899 76 CHEMBL401798 C09339 ZINC00898396 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853125 C[C@H]1c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45 InChI=1S/C19H19N/c1-11-14-5-3-4-13-10-16-18-12(8-9-20(16)2)6-7-15(11)19(18)17(13)14/h3-7,11,16H,8-10H2,1-2H3/t11-,16+/m0/s1 HGMQRIBEHJQILA-MEDUHNTESA-N 50087030 (1S,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::1,6-Dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL27132 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087030&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10706553 103986140 CHEMBL27132 ZINC13806928 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853127 CCCN1CCc2cc(F)cc-3c2[C@H]1Cc1cccc(OC=O)c-31 InChI=1S/C20H20FNO2/c1-2-7-22-8-6-14-9-15(21)11-16-19(14)17(22)10-13-4-3-5-18(20(13)16)24-12-23/h3-5,9,11-12,17H,2,6-8,10H2,1H3/t17-/m1/s1 XSLIKTVGDRTDPM-QGZVFWFLSA-N 50202303 CHEMBL258372::formic acid (R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202303&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44447997 104081880 CHEMBL258372 ZINC29041614 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853130 Oc1cccc2C[C@H]3NCCc4cccc(c34)-c12 InChI=1S/C16H15NO/c18-14-6-2-4-11-9-13-15-10(7-8-17-13)3-1-5-12(15)16(11)14/h1-6,13,17-18H,7-9H2/t13-/m1/s1 MHKSWTAPYIFAAP-CYBMUJFWSA-N 50052873 (R)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL332332 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052873&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10490043 103949613 CHEMBL332332 ZINC03651666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853131 COc1cc2C[C@@H]3N(C)CCc4c(Br)c(O)c(OC)c(-c2cc1OC)c34 InChI=1S/C20H22BrNO4/c1-22-6-5-11-16-13(22)7-10-8-14(24-2)15(25-3)9-12(10)17(16)20(26-4)19(23)18(11)21/h8-9,13,23H,5-7H2,1-4H3/t13-/m0/s1 OVHSYOZHNXMGQC-ZDUSSCGKSA-N 50202315 (S)-3-bromo-1,9,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol::CHEMBL401689 D(2) dopamine receptor Rattus norvegicus 610 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202315&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11567963 104081892 CHEMBL401689 ZINC29041648 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853133 COc1cc2C[C@@H]3N(C)CCc4cc(O)c(OC)c(-c2cc1OC)c34 InChI=1S/C20H23NO4/c1-21-6-5-11-8-15(22)20(25-4)19-13-10-17(24-3)16(23-2)9-12(13)7-14(21)18(11)19/h8-10,14,22H,5-7H2,1-4H3/t14-/m0/s1 OUTYMWDDJORZOH-AWEZNQCLSA-N 50202325 (+)-predicentrine::(S)-1,9,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol::CHEMBL404136::predicentrine D(2) dopamine receptor Rattus norvegicus 760 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10042942 104081902 CHEMBL404136 ZINC14677674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853134 COc1cc2CCNC3Cc4ccccc4Cc(c1)c23 InChI=1S/C18H19NO/c1-20-16-9-14-6-7-19-17-11-13-5-3-2-4-12(13)8-15(10-16)18(14)17/h2-5,9-10,17,19H,6-8,11H2,1H3 UPQALQKAFGLXPY-UHFFFAOYSA-N 50202328 5-methoxy-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene::CHEMBL402736 D(2) dopamine receptor Rattus norvegicus 19000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202328&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448063 104081905 CHEMBL402736 ZINC29041738 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853138 CCCN1CCc2cc(O)cc3Cc4ccccc4CC1c23 InChI=1S/C20H23NO/c1-2-8-21-9-7-16-11-18(22)12-17-10-14-5-3-4-6-15(14)13-19(21)20(16)17/h3-6,11-12,19,22H,2,7-10,13H2,1H3 KMEPUUUVCKDMTI-UHFFFAOYSA-N 50202326 1-propyl-1,2,3,7,12,12a-hexahydro-1-aza-pleiaden-5-ol::CHEMBL402517 D(2) dopamine receptor Rattus norvegicus 40000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448058 104081903 CHEMBL402517 ZINC29041721 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853139 CCCN1CCc2cc(F)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H20FNO2/c1-2-6-21-7-5-12-8-13(20)10-14-17(12)15(21)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,22-23H,2,5-7,9H2,1H3/t15-/m1/s1 TVIUJNLDORXPPC-OAHLLOKOSA-N 50013061 (R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL106622 D(2) dopamine receptor Rattus norvegicus 0.071 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013061&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131213 103925284 CHEMBL106622 ZINC26841490 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853141 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853143 CN1CCc2ccc3[C@@H](O)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H17NO/c1-19-8-7-10-5-6-13-17-15-11(9-14(19)16(10)17)3-2-4-12(15)18(13)20/h2-6,14,18,20H,7-9H2,1H3/t14-,18+/m1/s1 HIYLSOSERAQOHL-KDOFPFPSSA-N 50087034 (1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::CHEMBL285352 D(2) dopamine receptor Rattus norvegicus 210 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087034&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10754042 103986144 CHEMBL285352 ZINC13806910 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853144 CCc1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12 InChI=1S/C19H21N/c1-3-13-6-4-8-15-12-17-19-14(10-11-20(17)2)7-5-9-16(19)18(13)15/h4-9,17H,3,10-12H2,1-2H3/t17-/m1/s1 KCQGEEQDLXFPPZ-QGZVFWFLSA-N 50052864 (R)-11-Ethyl-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL118254 D(2) dopamine receptor Rattus norvegicus 79 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10061323 103949604 CHEMBL118254 ZINC13757616 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853146 CN1CCc2cc(O)cc3Cc4ccccc4CC1c23 InChI=1S/C18H19NO/c1-19-7-6-14-9-16(20)10-15-8-12-4-2-3-5-13(12)11-17(19)18(14)15/h2-5,9-10,17,20H,6-8,11H2,1H3 DZTLMFHPOVENDL-UHFFFAOYSA-N 50202330 1-methyl-1,2,3,7,12,12a-hexahydro-1-aza-pleiaden-5-ol::CHEMBL404865 D(2) dopamine receptor Rattus norvegicus 8900 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10355510 104081907 CHEMBL404865 ZINC29041714 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853147 COc1cc2Oc3c(O)ccc4CCN(C)[C@@H](Cc2cc1O)c34 InChI=1S/C18H19NO4/c1-19-6-5-10-3-4-13(20)18-17(10)12(19)7-11-8-14(21)16(22-2)9-15(11)23-18/h3-4,8-9,12,20-21H,5-7H2,1-2H3/t12-/m0/s1 NEQWPVBUZDJIHK-LBPRGKRZSA-N 50292457 Breoganine::CHEMBL452510 D(2) dopamine receptor Rattus norvegicus 200 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 177725 104134008 CHEMBL452510 ZINC29041598 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853148 CCCN1CCc2cc(O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO3/c1-2-6-20-7-5-12-8-13(21)10-14-17(12)15(20)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,21-23H,2,5-7,9H2,1H3/t15-/m1/s1 HLRBSTGXOFUEHW-OAHLLOKOSA-N 52987 (6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol;hydrate;hydrobromide::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::CHEMBL288096::MLS000860063::R( )-2,10,11-Trihydroxy-N-propyl-noraporphine hydrobromide hydrate::SMR000326921::cid_23640911 D(2) dopamine receptor Rattus norvegicus 0.053 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603798 252633121 CHEMBL288096 ZINC13111190 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853150 COc1cc-2c(C[C@@H]3N(C)CCc4cc(O)c(OC)c-2c34)cc1O InChI=1S/C19H21NO4/c1-20-5-4-10-7-15(22)19(24-3)18-12-9-16(23-2)14(21)8-11(12)6-13(20)17(10)18/h7-9,13,21-22H,4-6H2,1-3H3/t13-/m0/s1 LZJRNLRASBVRRX-ZDUSSCGKSA-N 50202318 (+)-boldine::(S)-(+)-Boldine::(S)-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol::CHEMBL388342::boldine::cid_10154::cid_248507 D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202318&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10154 104081895 CHEMBL388342 C09365 ZINC00135449 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853152 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m1/s1 WZJSIHGOLMMBAL-MRXNPFEDSA-N 84636 CHEMBL27559::NPA-11-OH-R,(+) D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333842 136350736 CHEMBL27559 ZINC05833984 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853156 CCCN1CCc2cc(O)c(O)c3Cc4ccccc4CC1c23 InChI=1S/C20H23NO2/c1-2-8-21-9-7-15-12-18(22)20(23)16-10-13-5-3-4-6-14(13)11-17(21)19(15)16/h3-6,12,17,22-23H,2,7-11H2,1H3 DOVBELPPXZSOPX-UHFFFAOYSA-N 50202331 1-propyl-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene-5,6-diol::CHEMBL404037 D(2) dopamine receptor Rattus norvegicus 6700 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202331&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448065 104081908 CHEMBL404037 ZINC29041749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853160 COc1ccc2C[C@@H]3N(C)CCc4ccc(O)c(Oc2c1O)c34 InChI=1S/C18H19NO4/c1-19-8-7-10-3-5-13(20)18-15(10)12(19)9-11-4-6-14(22-2)16(21)17(11)23-18/h3-6,12,20-21H,7-9H2,1-2H3/t12-/m0/s1 ZBTOEEFERPMYTH-LBPRGKRZSA-N 50292459 CHEMBL452512::Claviculine D(2) dopamine receptor Rattus norvegicus 1500 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 159034 104134010 CHEMBL452512 ZINC29041601 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853162 CN1CCc2ccc3[C@@H](NC(C)=O)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C20H20N2O/c1-11(23)21-20-14-5-3-4-13-10-16-18-12(8-9-22(16)2)6-7-15(20)19(18)17(13)14/h3-7,16,20H,8-10H2,1-2H3,(H,21,23)/t16-,20+/m1/s1 KCDYLYMPNGUYNO-UZLBHIALSA-N 50087038 CHEMBL27247::N-((1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-yl)-acetamide::N-(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-yl)-acetamide D(2) dopamine receptor Rattus norvegicus 8000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087038&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10780842 103986148 CHEMBL27247 ZINC13806918 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853163 CN1CCc2cc(cc-3c2[C@H]1Cc1cccc(O)c-31)-c1ccc(O)cc1 InChI=1S/C23H21NO2/c1-24-10-9-16-11-17(14-5-7-18(25)8-6-14)12-19-22(16)20(24)13-15-3-2-4-21(26)23(15)19/h2-8,11-12,20,25-26H,9-10,13H2,1H3/t20-/m1/s1 HQCQVUAWYQYIHX-HXUWFJFHSA-N 50202334 (R)-2-(4-hydroxy-phenyl)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL404137 D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44447996 104081911 CHEMBL404137 ZINC29041612 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853164 CN1CCc2ccc3oc(=O)c4cccc5C[C@@H]1c2c3c45 InChI=1S/C18H15NO2/c1-19-8-7-10-5-6-14-17-15-11(9-13(19)16(10)17)3-2-4-12(15)18(20)21-14/h2-6,13H,7-9H2,1H3/t13-/m1/s1 UCVKKWQVIIHPLH-CYBMUJFWSA-N 50096739 (R)-7-methyl-6a,7,8,9-tetrahydro-6H-1-oxa-7-aza-benzo[cd]pyren-2-one::CHEMBL124419 D(2) dopamine receptor Rattus norvegicus 540 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096739&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378785 103994216 CHEMBL124419 ZINC27194163 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853166 CN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C17H17NO/c1-18-9-8-11-4-2-6-13-16(11)14(18)10-12-5-3-7-15(19)17(12)13/h2-7,14,19H,8-10H2,1H3/t14-/m1/s1 PCGXWSCASZVBJT-CQSZACIVSA-N 50016013 (R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL119455::R-(-)-11-hydroxy-aporphine D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016013&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015045 103927694 CHEMBL119455 ZINC00002530 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853169 COc1ccc2C[C@@H]3N(C)CCc4cc5OCOc5c(c34)-c2c1O InChI=1S/C19H19NO4/c1-20-6-5-11-8-14-19(24-9-23-14)17-15(11)12(20)7-10-3-4-13(22-2)18(21)16(10)17/h3-4,8,12,21H,5-7,9H2,1-2H3/t12-/m0/s1 LODGIKWNLDQZBM-LBPRGKRZSA-N 50016018 (S)-11-methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-12-ol::11-Methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-12-ol (Bulbocapnine)::Bulbocapnine::CHEMBL157912 D(2) dopamine receptor Rattus norvegicus 14000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50016018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50016018&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 12441 103927699 CHEMBL157912 C09367 ZINC00000103 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853174 CN1CCc2ccc3[C@@H](N)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C18H18N2/c1-20-8-7-10-5-6-13-17-15-11(9-14(20)16(10)17)3-2-4-12(15)18(13)19/h2-6,14,18H,7-9,19H2,1H3/t14-,18+/m1/s1 DAKGDRVNCPHAPY-KDOFPFPSSA-N 50087024 (1S,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ylamine::CHEMBL27251 D(2) dopamine receptor Rattus norvegicus 2250 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10084076 103986134 CHEMBL27251 ZINC13806922 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853175 CCN1CCc2cc(O)cc3Oc4ccccc4CC1c23 InChI=1S/C18H19NO2/c1-2-19-8-7-13-9-14(20)11-17-18(13)15(19)10-12-5-3-4-6-16(12)21-17/h3-6,9,11,15,20H,2,7-8,10H2,1H3 KAUFSVBKTMJNMB-UHFFFAOYSA-N 50202302 1-ethyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-5-ol::CHEMBL439639 D(2) dopamine receptor Rattus norvegicus 6500 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202302&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10707972 104081879 CHEMBL439639 ZINC13805089 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853179 C[C@@H]1c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45 InChI=1S/C19H19N/c1-11-14-5-3-4-13-10-16-18-12(8-9-20(16)2)6-7-15(11)19(18)17(13)14/h3-7,11,16H,8-10H2,1-2H3/t11-,16-/m1/s1 HGMQRIBEHJQILA-BDJLRTHQSA-N 50087025 (1R,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::1,6-Dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL282863 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087025&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10825325 103986135 CHEMBL282863 ZINC13806925 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853181 COc1c(O)c2-c3ccc(O)cc3C(C)(C)c3nccc(c1OC)c23 InChI=1S/C20H19NO4/c1-20(2)13-9-10(22)5-6-11(13)14-15-12(7-8-21-19(15)20)17(24-3)18(25-4)16(14)23/h5-9,22-23H,1-4H3 CUEIWVZJOPCMPT-UHFFFAOYSA-N 50202290 2,3-dimethoxy-7,7-dimethyl-7H-dibenzo[de,g]quinoline-1,9-diol::CHEMBL257958::Melosmine D(2) dopamine receptor Rattus norvegicus 80000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5464379 104081867 CHEMBL257958 ZINC01842528 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853183 COc1c(O)c2-c3ccccc3C[C@H]3NCCc(c1OC)c23 InChI=1S/C18H19NO3/c1-21-17-12-7-8-19-13-9-10-5-3-4-6-11(10)15(14(12)13)16(20)18(17)22-2/h3-6,13,19-20H,7-9H2,1-2H3/t13-/m1/s1 XLXSXOHBVGWKMT-CYBMUJFWSA-N 50292445 CHEMBL508011::Isopiline D(2) dopamine receptor Rattus norvegicus 30000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13891896 104133996 CHEMBL508011 ZINC14775234 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853184 CN1CCc2ccc3[C@H](NC(C)=O)c4cccc5C[C@@H]1c2c3-c45 InChI=1S/C20H20N2O/c1-11(23)21-20-14-5-3-4-13-10-16-18-12(8-9-22(16)2)6-7-15(20)19(18)17(13)14/h3-7,16,20H,8-10H2,1-2H3,(H,21,23)/t16-,20-/m1/s1 KCDYLYMPNGUYNO-OXQOHEQNSA-N 50087032 CHEMBL282375::N-((1R,5aR)-6-methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-yl)-acetamide::N-(6-Methyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-yl)-acetamide D(2) dopamine receptor Rattus norvegicus 3600 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087032&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10662302 103986142 CHEMBL282375 ZINC13806916 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853187 COc1cccc2CC3N(C)CCc4cc5OCOc5c(c34)-c12 InChI=1S/C19H19NO3/c1-20-7-6-12-9-15-19(23-10-22-15)18-16(12)13(20)8-11-4-3-5-14(21-2)17(11)18/h3-5,9,13H,6-8,10H2,1-2H3 SKQCMMAAFNFEPY-UHFFFAOYSA-N 50202320 12-methoxy-7-methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline::CHEMBL257956 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44447994 104081897 CHEMBL257956 ZINC14683249 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853190 COc1cc-2c(C[C@@H]3N(C)CCc4c(I)c(O)c(OC)c-2c34)cc1O InChI=1S/C19H20INO4/c1-21-5-4-10-15-12(21)6-9-7-13(22)14(24-2)8-11(9)16(15)19(25-3)18(23)17(10)20/h7-8,12,22-23H,4-6H2,1-3H3/t12-/m0/s1 YCBIBKGMUXWRRT-LBPRGKRZSA-N 50202337 (S)-3-iodo-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol::3-Iodoboldine::CHEMBL256075 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10004036 104081914 CHEMBL256075 ZINC29041634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853191 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2C#N)c-31 InChI=1S/C25H22N2/c1-16-6-3-9-19(15-26)23(16)20-10-5-8-18-14-22-25-17(12-13-27(22)2)7-4-11-21(25)24(18)20/h3-11,22H,12-14H2,1-2H3/t22-/m1/s1 APEZAWGOFKUHCA-JOCHJYFZSA-N 50098549 (6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::(6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::3-Methyl-2-((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-benzonitrile::CHEMBL28056 D(2) dopamine receptor Rattus norvegicus 500 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098549&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11725453 103995562 CHEMBL28056 ZINC01493886 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853197 Cc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O InChI=1S/C17H17NO/c1-10-5-6-12-9-14-15-11(7-8-18-14)3-2-4-13(15)16(12)17(10)19/h2-6,14,18-19H,7-9H2,1H3/t14-/m1/s1 MNRGHKYZSUNTQE-CQSZACIVSA-N 50052859 (R)-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL116367 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264172 103949599 CHEMBL116367 ZINC13757608 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853200 CN1CCc2ccc3[nH]c(=O)c4cccc5C[C@@H]1c2c3c45 InChI=1S/C18H16N2O/c1-20-8-7-10-5-6-13-17-15-11(9-14(20)16(10)17)3-2-4-12(15)18(21)19-13/h2-6,14H,7-9H2,1H3,(H,19,21)/t14-/m1/s1 GTFWUPYRBYXCRC-CQSZACIVSA-N 50202298 (R)-7-Methyl-1,6,6a,7,8,9-hexahydro-1,7-diaza-benzo[cd]pyren-2-one::CHEMBL253318 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202298&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448054 104081875 CHEMBL253318 ZINC27199044 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853202 CN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 InChI=1S/C18H19NO/c1-11-6-7-13-10-15-16-12(8-9-19(15)2)4-3-5-14(16)17(13)18(11)20/h3-7,15,20H,8-10H2,1-2H3/t15-/m1/s1 YGOZTDLAUVOPMF-OAHLLOKOSA-N 50036286 (R)-(-)-10-methyl-11-hydroxyaporphine::(R)-6,10-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL53510 D(2) dopamine receptor Rattus norvegicus 1070 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3082625 103944104 CHEMBL53510 ZINC00006368 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853203 COc1cc2CCNC3Cc4ccccc4Cc(c1OC)c23 InChI=1S/C19H21NO2/c1-21-17-11-14-7-8-20-16-10-13-6-4-3-5-12(13)9-15(18(14)16)19(17)22-2/h3-6,11,16,20H,7-10H2,1-2H3 JNAQRWLPUGNYTB-UHFFFAOYSA-N 50202319 5,6-dimethoxy-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene::CHEMBL254147 D(2) dopamine receptor Rattus norvegicus 13000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448070 104081896 CHEMBL254147 ZINC29041768 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853206 CN1CCc2ccc3Cc4cccc5C[C@]1(C)c2c3-c45 InChI=1S/C19H19N/c1-19-11-15-5-3-4-13-10-14-7-6-12(8-9-20(19)2)18(19)17(14)16(13)15/h3-7H,8-11H2,1-2H3/t19-/m1/s1 AHBOSRZKKHTKEU-LJQANCHMSA-N 50202332 (R)-5a,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL403844 D(2) dopamine receptor Rattus norvegicus 83 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202332&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448044 104081909 CHEMBL403844 ZINC29041670 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853208 CN1CCc2cc3OCOc3c-3c2C1Cc1cccc(O)c-31 InChI=1S/C18H17NO3/c1-19-6-5-11-8-14-18(22-9-21-14)17-15(11)12(19)7-10-3-2-4-13(20)16(10)17/h2-4,8,12,20H,5-7,9H2,1H3 IKMXUUHNYQWZBC-UHFFFAOYSA-N 50202309 7-methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinolin-12-ol::CHEMBL258370 D(2) dopamine receptor Rattus norvegicus 600 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202309&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3496768 104081886 CHEMBL258370 ZINC14683238 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853210 CN1CCc2ccc3c4c2[C@H]1Cc1cccc(oc3=O)c41 InChI=1S/C18H15NO2/c1-19-8-7-10-5-6-12-17-15(10)13(19)9-11-3-2-4-14(16(11)17)21-18(12)20/h2-6,13H,7-9H2,1H3/t13-/m1/s1 HJZYUBCMOFCAGG-CYBMUJFWSA-N 50096740 (R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-benzo[cd]pyren-1-one::CHEMBL122485 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096740&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44347445 103994217 CHEMBL122485 ZINC27201394 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853211 COc1cc2CCN(Cc3ccccc3)C3Cc4ccccc4Cc(c1OC)c23 InChI=1S/C26H27NO2/c1-28-24-16-21-12-13-27(17-18-8-4-3-5-9-18)23-15-20-11-7-6-10-19(20)14-22(25(21)23)26(24)29-2/h3-11,16,23H,12-15,17H2,1-2H3 JFSITZSZKVIEHK-UHFFFAOYSA-N 50202324 1-benzyl-5,6-dimethoxy-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene::CHEMBL253949 D(2) dopamine receptor Rattus norvegicus 4900 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448068 104081901 CHEMBL253949 ZINC29041760 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853212 CCCCC(=O)Oc1cccc2C[C@H]3N(CCC)CCc4cccc(c34)-c12 InChI=1S/C24H29NO2/c1-3-5-12-22(26)27-21-11-7-9-18-16-20-23-17(13-15-25(20)14-4-2)8-6-10-19(23)24(18)21/h6-11,20H,3-5,12-16H2,1-2H3/t20-/m1/s1 JGCVBGVDWQJTDF-HXUWFJFHSA-N 50202292 11-valeryloxynoraporphine::CHEMBL403550::Pentanoic acid (R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester D(2) dopamine receptor Rattus norvegicus 34 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202292&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44447998 104081869 CHEMBL403550 ZINC29041617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853213 CN1CCc2ccc3c4-c5c(cccc5C[C@@H]1c24)[C@@]3(C)O InChI=1S/C19H19NO/c1-19(21)13-5-3-4-12-10-15-17-11(8-9-20(15)2)6-7-14(19)18(17)16(12)13/h3-7,15,21H,8-10H2,1-2H3/t15-,19-/m1/s1 UIYKUTOPDMMXAX-DNVCBOLYSA-N 50087039 (1R,5aR)-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::1,6-Dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylen-1-ol::CHEMBL27309 D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10683945 103986149 CHEMBL27309 ZINC13806913 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853214 CO[C@]1(C)c2cccc3C[C@H]4N(C)CCc5ccc1c(-c23)c45 InChI=1S/C20H21NO/c1-20(22-3)14-6-4-5-13-11-16-18-12(9-10-21(16)2)7-8-15(20)19(18)17(13)14/h4-8,16H,9-11H2,1-3H3/t16-,20-/m1/s1 JVZCJQBRRXZMQR-OXQOHEQNSA-N 50087033 (1R,5aR)-1-methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::1-Methoxy-1,6-dimethyl-1,5,5a,6,7,8-hexahydro-6-aza-benzo[mno]aceanthrylene::CHEMBL281924 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50087033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50087033&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10062885 103986143 CHEMBL281924 ZINC13806931 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853215 CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H23NO3/c1-3-7-21-8-6-13-9-14(24-2)11-15-18(13)16(21)10-12-4-5-17(22)20(23)19(12)15/h4-5,9,11,16,22-23H,3,6-8,10H2,1-2H3/t16-/m1/s1 WNNMRMNAGNMVEW-MRXNPFEDSA-N 50010692 (R)-(-)-2-methoxy-N-npropylnorapomorphine::(R)-2-methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53294 D(2) dopamine receptor Rattus norvegicus 10.2 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130907 103923438 CHEMBL53294 ZINC00011666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853219 CN1CCc2cccc3Oc4ccc(O)cc4CC1c23 InChI=1S/C17H17NO2/c1-18-8-7-11-3-2-4-16-17(11)14(18)10-12-9-13(19)5-6-15(12)20-16/h2-6,9,14,19H,7-8,10H2,1H3 YYADTQZDIVKTET-UHFFFAOYSA-N 50202327 1-methyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-10-ol::CHEMBL155352 D(2) dopamine receptor Rattus norvegicus 720 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264969 104081904 CHEMBL155352 ZINC12355991 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853222 COc1cc2C[C@@H]3N(C)CCc4ccc(O)c(Oc2cc1O)c34 InChI=1S/C18H19NO4/c1-19-6-5-10-3-4-13(20)18-17(10)12(19)7-11-8-16(22-2)14(21)9-15(11)23-18/h3-4,8-9,12,20-21H,5-7H2,1-2H3/t12-/m0/s1 VRFVDWALYCNYTM-LBPRGKRZSA-N 50292460 CHEMBL452776::Celtisine D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292460&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 146299 104134011 CHEMBL452776 ZINC29041606 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853234 CCN1CCc2cc(O)c(O)c3Cc4ccccc4CC1c23 InChI=1S/C19H21NO2/c1-2-20-8-7-14-11-17(21)19(22)15-9-12-5-3-4-6-13(12)10-16(20)18(14)15/h3-6,11,16,21-22H,2,7-10H2,1H3 CUNRTIQBXJTHDC-UHFFFAOYSA-N 50202336 1-ethyl-1,2,3,7,12,12a-hexahydro-1-aza-pleiadene-5,6-diol::CHEMBL253947 D(2) dopamine receptor Rattus norvegicus 16000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448064 104081913 CHEMBL253947 ZINC29041746 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853236 Oc1cc2CCNC3Cc4ccccc4Cc(c1O)c23 InChI=1S/C17H17NO2/c19-15-9-12-5-6-18-14-8-11-4-2-1-3-10(11)7-13(16(12)14)17(15)20/h1-4,9,14,18-20H,5-8H2 SVRDMCXMTWERHI-UHFFFAOYSA-N 50202297 1,2,3,7,12,12a-hexahydro-1-aza-pleiadene-5,6-diol::CHEMBL253948 D(2) dopamine receptor Rattus norvegicus 8000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202297&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448066 104081874 CHEMBL253948 ZINC29041753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853238 COc1cc2C[C@@H]3N(C)CCc4c(I)c(OC)c(OC)c(-c2cc1OC)c34 InChI=1S/C21H24INO4/c1-23-7-6-12-17-14(23)8-11-9-15(24-2)16(25-3)10-13(11)18(17)20(26-4)21(27-5)19(12)22/h9-10,14H,6-8H2,1-5H3/t14-/m0/s1 VORDXXSSORDUOI-AWEZNQCLSA-N 50202295 (S)-3-iodo-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL401567 D(2) dopamine receptor Rattus norvegicus 4500 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202295&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44448027 104081872 CHEMBL401567 ZINC29041642 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853239 CN1CCc2ccc3c4c2[C@H]1Cc1cccc([nH]c3=O)c41 InChI=1S/C18H16N2O/c1-20-8-7-10-5-6-12-17-15-11(9-14(20)16(10)17)3-2-4-13(15)19-18(12)21/h2-6,14H,7-9H2,1H3,(H,19,21)/t14-/m1/s1 DTLGJDYEVFKDLJ-CQSZACIVSA-N 50202333 (R)-7-Methyl-6a,7,8,9-tetrahydro-2H,6H-2,7-diaza-benzo[cd]pyren-1-one::CHEMBL253319 D(2) dopamine receptor Rattus norvegicus 6100 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202333&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333670 104081910 CHEMBL253319 ZINC27197072 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853244 CCCN1CCc2cc(O)cc3Oc4ccccc4CC1c23 InChI=1S/C19H21NO2/c1-2-8-20-9-7-14-10-15(21)12-18-19(14)16(20)11-13-5-3-4-6-17(13)22-18/h3-6,10,12,16,21H,2,7-9,11H2,1H3 KAVZPHXMOSLALD-UHFFFAOYSA-N 50202339 1-propyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-5-ol::CHEMBL155066 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10589979 104081916 CHEMBL155066 ZINC13805094 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853249 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(C)c(O)c-31 InChI=1S/C20H23NO/c1-3-10-21-11-9-14-5-4-6-16-18(14)17(21)12-15-8-7-13(2)20(22)19(15)16/h4-8,17,22H,3,9-12H2,1-2H3/t17-/m1/s1 OJGAXSYOOYSPGN-QGZVFWFLSA-N 50052851 (R)-10-Methyl-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL119593 D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052851&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10613676 103949591 CHEMBL119593 ZINC13757602 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853251 COc1cc2C[C@@H]3N(C)CCc4c(Br)c(OC)c(OC)c(-c2cc1OC)c34 InChI=1S/C21H24BrNO4/c1-23-7-6-12-17-14(23)8-11-9-15(24-2)16(25-3)10-13(11)18(17)20(26-4)21(27-5)19(12)22/h9-10,14H,6-8H2,1-5H3/t14-/m0/s1 UBIRBSHOBFFLDX-AWEZNQCLSA-N 50202335 (S)-3-bromo-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL403032 D(2) dopamine receptor Rattus norvegicus 2400 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202335&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1257607 104081912 CHEMBL403032 ZINC12416784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853257 COc1c2OCOc2c2-c3ccccc3C[C@H]3NCCc1c23 InChI=1S/C18H17NO3/c1-20-16-12-6-7-19-13-8-10-4-2-3-5-11(10)15(14(12)13)17-18(16)22-9-21-17/h2-5,13,19H,6-9H2,1H3/t13-/m1/s1 TYZKUSBTFHNPMV-CYBMUJFWSA-N 50202300 (R)-4-methoxy-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline::CHEMBL257745::Norstephalagine D(2) dopamine receptor Rattus norvegicus 27000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202300&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 133381 104081877 CHEMBL257745 ZINC29041592 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853261 CCCN1CCc2cccc-3c2[C@@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m0/s1 WZJSIHGOLMMBAL-INIZCTEOSA-N 50023739 (S)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL283489 D(2) dopamine receptor Rattus norvegicus 105 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023739&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13922235 103934080 CHEMBL283489 ZINC05833961 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853265 CCCCCCCCCCCCCCCCCCCCCC(=O)Oc1cccc2C[C@H]3N(CCC)CCc4cccc(c34)-c12 InChI=1S/C41H63NO2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-29-39(43)44-38-28-24-26-35-33-37-40-34(30-32-42(37)31-4-2)25-23-27-36(40)41(35)38/h23-28,37H,3-22,29-33H2,1-2H3/t37-/m1/s1 PVYSPGIMGUUTAL-DIPNUNPCSA-N 50202338 CHEMBL257394::docosanoic acid (R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl ester D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44447999 104081915 CHEMBL257394 ZINC36093105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853268 COc1cc-2c(C[C@@H]3N(C)CCc4c(Br)c(O)c(OC)c-2c34)cc1O InChI=1S/C19H20BrNO4/c1-21-5-4-10-15-12(21)6-9-7-13(22)14(24-2)8-11(9)16(15)19(25-3)18(23)17(10)20/h7-8,12,22-23H,4-6H2,1-3H3/t12-/m0/s1 ORZPHDSNVICTTE-LBPRGKRZSA-N 50202340 (S)-3-bromo-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol::3-bromoboldine::CHEMBL225853 D(2) dopamine receptor Rattus norvegicus 740 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10409038 104081917 CHEMBL225853 ZINC28647492 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853271 CCCN1CCc2cccc3Oc4ccc(O)cc4CC1c23 InChI=1S/C19H21NO2/c1-2-9-20-10-8-13-4-3-5-18-19(13)16(20)12-14-11-15(21)6-7-17(14)22-18/h3-7,11,16,21H,2,8-10,12H2,1H3 JKQPZWDOWPWNQV-UHFFFAOYSA-N 50202304 1-Propyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-10-ol::CHEMBL345240 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202304&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10685300 104081881 CHEMBL345240 ZINC13805122 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853274 CN1CCc2cccc-3c2[C@H]1Cc1cccc(-c2c(C)cccc2O)c-31 InChI=1S/C24H23NO/c1-15-6-3-11-21(26)22(15)18-9-5-8-17-14-20-24-16(12-13-25(20)2)7-4-10-19(24)23(17)18/h3-11,20,26H,12-14H2,1-2H3/t20-/m1/s1 QQYBSVWWEQVBIX-HXUWFJFHSA-N 50098544 (6aR,aR)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::(6aR,aS)-3-Methyl-2-(6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::3-methyl-2-((R)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-yl)-phenol::CHEMBL26907 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50098544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50098544&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10593348 103995557 CHEMBL26907 ZINC13531273 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50853275 CCCN1CCc2cc(O)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO3/c1-2-6-20-7-5-12-8-13(21)10-14-17(12)15(20)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,21-23H,2,5-7,9H2,1H3/t15-/m1/s1 HLRBSTGXOFUEHW-OAHLLOKOSA-N 52987 (6aR)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol;hydrate;hydrobromide::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,10,11-triol::CHEMBL288096::MLS000860063::R( )-2,10,11-Trihydroxy-N-propyl-noraporphine hydrobromide hydrate::SMR000326921::cid_23640911 D(2) dopamine receptor Rattus norvegicus 0.07 ChEMBL 10.1021/jm060959i 10.7270/Q22J6CPJ 17228858 Zhang, A; Zhang, Y; Branfman, AR; Baldessarini, RJ; Neumeyer, JL Chinese Academy of Sciences http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52987&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6603798 252633121 CHEMBL288096 ZINC13111190 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50862507 S=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1 InChI=1S/C21H31N3S2/c25-21-24(19-10-4-5-11-20(19)26-21)13-7-6-12-22-14-16-23(17-15-22)18-8-2-1-3-9-18/h4-5,10-11,18H,1-3,6-9,12-17H2 FJGOTAJCEJCFEV-UHFFFAOYSA-N 50374598 CHEMBL272603::US9604926, Compound CM-156::US9724435, Compound CM-156 D(2) dopamine receptor Rattus norvegicus 1041 ChEMBL 10.1021/jm701357m 10.7270/Q2736RTZ 18278854 Mesangeau, C; Narayanan, S; Green, AM; Shaikh, J; Kaushal, N; Viard, E; Xu, YT; Fishback, JA; Poupaert, JH; Matsumoto, RR; McCurdy, CR The University of Mississippi http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374598&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 17756659 160853688 CHEMBL272603 ZINC29134265 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50877840 COc1ccc2CC(CN3CCN(CC3)c3ccccn3)CCc2c1 InChI=1S/C21H27N3O/c1-25-20-8-7-18-14-17(5-6-19(18)15-20)16-23-10-12-24(13-11-23)21-4-2-3-9-22-21/h2-4,7-9,15,17H,5-6,10-14,16H2,1H3 UQISWIRNAUDVMP-UHFFFAOYSA-N 50107253 1-((6-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)methyl)-4-(pyridin-2-yl)piperazine::1-(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-ylmethyl)-4-pyridin-2-yl-piperazine::CHEMBL138900 D(2) dopamine receptor Rattus norvegicus >850 ChEMBL 10.1021/jm800965b 10.7270/Q21837D3 19053780 Berardi, F; Abate, C; Ferorelli, S; de Robertis, AF; Leopoldo, M; Colabufo, NA; Niso, M; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107253&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11002234 104002674 CHEMBL138900 ZINC13470682 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50877841 COc1cccc(c1)[C@@H]1CC[C@@H](CC1)NCCOc1ccccn1 InChI=1S/C20H26N2O2/c1-23-19-6-4-5-17(15-19)16-8-10-18(11-9-16)21-13-14-24-20-7-2-3-12-22-20/h2-7,12,15-16,18,21H,8-11,13-14H2,1H3/t16-,18+ QEJVHQDLWUVNET-MAEOIBBWSA-N 50275280 CHEMBL487359::cis-4-(3-methoxyphenyl)-N-(2-(pyridin-2-yloxy)ethyl)cyclohexanamine D(2) dopamine receptor Rattus norvegicus 783 ChEMBL 10.1021/jm800965b 10.7270/Q21837D3 19053780 Berardi, F; Abate, C; Ferorelli, S; de Robertis, AF; Leopoldo, M; Colabufo, NA; Niso, M; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50275280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50275280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10892762 104118795 CHEMBL487359 ZINC13470716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50877842 COc1cccc(c1)C1=CCC(CC1)N1CCN(CC1)c1ccccc1 InChI=1S/C23H28N2O/c1-26-23-9-5-6-20(18-23)19-10-12-22(13-11-19)25-16-14-24(15-17-25)21-7-3-2-4-8-21/h2-10,18,22H,11-17H2,1H3 MCVMARUOYHWORW-UHFFFAOYSA-N 50107251 1-(4-(3-methoxyphenyl)cyclohex-3-enyl)-4-phenylpiperazine::1-[4-(3-Methoxy-phenyl)-cyclohex-3-enyl]-4-phenyl-piperazine::CHEMBL139848 D(2) dopamine receptor Rattus norvegicus 2190 ChEMBL 10.1021/jm800965b 10.7270/Q21837D3 19053780 Berardi, F; Abate, C; Ferorelli, S; de Robertis, AF; Leopoldo, M; Colabufo, NA; Niso, M; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11068038 104002672 CHEMBL139848 ZINC13470699 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50877843 COc1cccc(c1)C1=CCC(CC1)N1CCN(CC1)c1ccccn1 InChI=1S/C22H27N3O/c1-26-21-6-4-5-19(17-21)18-8-10-20(11-9-18)24-13-15-25(16-14-24)22-7-2-3-12-23-22/h2-8,12,17,20H,9-11,13-16H2,1H3 DQBQKYJWMSLVPS-UHFFFAOYSA-N 50107247 1-(4-(3-methoxyphenyl)cyclohex-3-enyl)-4-(pyridin-2-yl)piperazine::1-[4-(3-Methoxy-phenyl)-cyclohex-3-enyl]-4-pyridin-2-yl-piperazine::CHEMBL140287 D(2) dopamine receptor Rattus norvegicus 1220 ChEMBL 10.1021/jm800965b 10.7270/Q21837D3 19053780 Berardi, F; Abate, C; Ferorelli, S; de Robertis, AF; Leopoldo, M; Colabufo, NA; Niso, M; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50107247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50107247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10948076 104002668 CHEMBL140287 ZINC13470695 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50877844 COc1cccc(c1)[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1cccc2ccccc12 InChI=1S/C27H32N2O/c1-30-25-9-4-8-23(20-25)21-12-14-24(15-13-21)28-16-18-29(19-17-28)27-11-5-7-22-6-2-3-10-26(22)27/h2-11,20-21,24H,12-19H2,1H3/t21-,24+ RBBSEEBITXSZAO-PEPAQOBHSA-N 50275281 CHEMBL487360::cis-1-(4-(3-methoxyphenyl)cyclohexyl)-4-(naphthalen-1-yl)piperazine D(2) dopamine receptor Rattus norvegicus 1310 ChEMBL 10.1021/jm800965b 10.7270/Q21837D3 19053780 Berardi, F; Abate, C; Ferorelli, S; de Robertis, AF; Leopoldo, M; Colabufo, NA; Niso, M; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50275281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50275281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10938233 104118796 CHEMBL487360 ZINC13470724 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50877845 COc1cccc(c1)[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccc1 InChI=1S/C23H30N2O/c1-26-23-9-5-6-20(18-23)19-10-12-22(13-11-19)25-16-14-24(15-17-25)21-7-3-2-4-8-21/h2-9,18-19,22H,10-17H2,1H3/t19-,22+ XCLCSOAFYUDOLP-IQGASKDCSA-N 50275319 CHEMBL485728::cis-1-(4-(3-methoxyphenyl)cyclohexyl)-4-phenylpiperazine D(2) dopamine receptor Rattus norvegicus 2380 ChEMBL 10.1021/jm800965b 10.7270/Q21837D3 19053780 Berardi, F; Abate, C; Ferorelli, S; de Robertis, AF; Leopoldo, M; Colabufo, NA; Niso, M; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50275319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50275319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10247330 104118830 CHEMBL485728 ZINC13470719 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50877846 COc1ccccc1[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1 InChI=1S/C22H29N3O/c1-26-21-7-3-2-6-20(21)18-9-11-19(12-10-18)24-14-16-25(17-15-24)22-8-4-5-13-23-22/h2-8,13,18-19H,9-12,14-17H2,1H3/t18-,19+ FCPLDXWPGMEXLL-KDURUIRLSA-N 50275320 CHEMBL485729::cis-1-(4-(2-methoxyphenyl)cyclohexyl)-4-(pyridin-2-yl)piperazine D(2) dopamine receptor Rattus norvegicus 2120 ChEMBL 10.1021/jm800965b 10.7270/Q21837D3 19053780 Berardi, F; Abate, C; Ferorelli, S; de Robertis, AF; Leopoldo, M; Colabufo, NA; Niso, M; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50275320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50275320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10871856 104118831 CHEMBL485729 ZINC12356161 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50877847 COc1cccc(c1)[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1 InChI=1S/C22H29N3O/c1-26-21-6-4-5-19(17-21)18-8-10-20(11-9-18)24-13-15-25(16-14-24)22-7-2-3-12-23-22/h2-7,12,17-18,20H,8-11,13-16H2,1H3/t18-,20+ SHEZXZSIBXLQMP-PUZFROQSSA-N 50275321 CHEMBL521350::cis-1-(4-(3-methoxyphenyl)cyclohexyl)-4-(pyridin-2-yl)piperazine D(2) dopamine receptor Rattus norvegicus >850 ChEMBL 10.1021/jm800965b 10.7270/Q21837D3 19053780 Berardi, F; Abate, C; Ferorelli, S; de Robertis, AF; Leopoldo, M; Colabufo, NA; Niso, M; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50275321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50275321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10020855 104118832 CHEMBL521350 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50877848 COc1ccc(cc1)[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1 InChI=1S/C22H29N3O/c1-26-21-11-7-19(8-12-21)18-5-9-20(10-6-18)24-14-16-25(17-15-24)22-4-2-3-13-23-22/h2-4,7-8,11-13,18,20H,5-6,9-10,14-17H2,1H3/t18-,20+ PQGLTWUOVHNAGW-PUZFROQSSA-N 50275322 CHEMBL485929::cis-1-(4-(4-methoxyphenyl)cyclohexyl)-4-(pyridin-2-yl)piperazine D(2) dopamine receptor Rattus norvegicus 787 ChEMBL 10.1021/jm800965b 10.7270/Q21837D3 19053780 Berardi, F; Abate, C; Ferorelli, S; de Robertis, AF; Leopoldo, M; Colabufo, NA; Niso, M; Perrone, R Universita degli Studi di Bari http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50275322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50275322&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10383331 104118833 CHEMBL485929 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50903435 Fc1ccc2c(c1)nc(N1CCN(Cc3cnc[nH]3)CC1)c1cccn21 InChI=1S/C19H19FN6/c20-14-3-4-17-16(10-14)23-19(18-2-1-5-26(17)18)25-8-6-24(7-9-25)12-15-11-21-13-22-15/h1-5,10-11,13H,6-9,12H2,(H,21,22) BRNJLENJYHXKEL-UHFFFAOYSA-N 50299660 7-fluoro-4-(4-((3H-imidazol-4-yl)methyl)piperazin-1-yl)-pyrrolo[1,2-a]quinoxaline::CHEMBL566522 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm901126m 10.7270/Q2H9963M 19831400 Butini, S; Budriesi, R; Hamon, M; Morelli, E; Gemma, S; Brindisi, M; Borrelli, G; Novellino, E; Fiorini, I; Ioan, P; Chiarini, A; Cagnotto, A; Mennini, T; Fracasso, C; Caccia, S; Campiani, G European Research Centre for Drug Discovery and Development (NatSynDrugs) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299660&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44541937 104141189 CHEMBL566522 ZINC45245703 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50903439 Cc1cccc2nc(N3CCN(Cc4cnc[nH]4)CC3)c3cccn3c12 InChI=1S/C20H22N6/c1-15-4-2-5-17-19(15)26-7-3-6-18(26)20(23-17)25-10-8-24(9-11-25)13-16-12-21-14-22-16/h2-7,12,14H,8-11,13H2,1H3,(H,21,22) UXCYHZPVNXGIRJ-UHFFFAOYSA-N 50299661 9-methyl-4-(4-((3H-imidazol-4-yl)methyl)piperazin-1-yl)-pyrrolo[1,2-a]quinoxaline::CHEMBL582992 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm901126m 10.7270/Q2H9963M 19831400 Butini, S; Budriesi, R; Hamon, M; Morelli, E; Gemma, S; Brindisi, M; Borrelli, G; Novellino, E; Fiorini, I; Ioan, P; Chiarini, A; Cagnotto, A; Mennini, T; Fracasso, C; Caccia, S; Campiani, G European Research Centre for Drug Discovery and Development (NatSynDrugs) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299661&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44541941 104141190 CHEMBL582992 ZINC45319362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50903444 Fc1ccc2c(c1)nc(N1CCN(Cc3ncc[nH]3)CC1)c1cccn21 InChI=1S/C19H19FN6/c20-14-3-4-16-15(12-14)23-19(17-2-1-7-26(16)17)25-10-8-24(9-11-25)13-18-21-5-6-22-18/h1-7,12H,8-11,13H2,(H,21,22) GLAKGIIOQOOKAC-UHFFFAOYSA-N 50299662 7-fluoro-4-(4-((1H-imidazol-2-yl)methyl)piperazin-1-yl)-pyrrolo[1,2-a]quinoxaline::CHEMBL571046 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm901126m 10.7270/Q2H9963M 19831400 Butini, S; Budriesi, R; Hamon, M; Morelli, E; Gemma, S; Brindisi, M; Borrelli, G; Novellino, E; Fiorini, I; Ioan, P; Chiarini, A; Cagnotto, A; Mennini, T; Fracasso, C; Caccia, S; Campiani, G European Research Centre for Drug Discovery and Development (NatSynDrugs) http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299662&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44542076 104141191 CHEMBL571046 ZINC45261462 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921365 CCCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C21H24FNO2/c1-2-8-23-9-6-15-11-16(25-10-7-22)13-17-20(15)18(23)12-14-4-3-5-19(24)21(14)17/h3-5,11,13,18,24H,2,6-10,12H2,1H3/t18-/m1/s1 SWSVYEJPIAYSGL-GOSISDBHSA-N 50336861 CHEMBL1672310::N-propyl-2-fluoroethoxy-11-monohydroxy aporphine D(2) dopamine receptor Rattus norvegicus 3.5 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939978 125086963 CHEMBL1672310 ZINC66077822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921366 CCN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C21H24FNO2/c1-2-23-9-7-15-11-16(25-10-4-8-22)13-17-20(15)18(23)12-14-5-3-6-19(24)21(14)17/h3,5-6,11,13,18,24H,2,4,7-10,12H2,1H3/t18-/m1/s1 LODBNYQJHVOXNX-GOSISDBHSA-N 50336862 CHEMBL1672311::N-ethyl-2-fluoropropanoxy-11-monohydroxy aporphine D(2) dopamine receptor Rattus norvegicus 3.2 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939979 125086964 CHEMBL1672311 ZINC66077823 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921367 CCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C20H22FNO2/c1-2-22-8-6-14-10-15(24-9-7-21)12-16-19(14)17(22)11-13-4-3-5-18(23)20(13)16/h3-5,10,12,17,23H,2,6-9,11H2,1H3/t17-/m1/s1 ZAJYDMAAHSFWGH-QGZVFWFLSA-N 50336863 (R)-6-ethyl-2-(2-fluoroethoxy)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL1672312 D(2) dopamine receptor Rattus norvegicus 0.83 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939980 125086965 CHEMBL1672312 ZINC66098523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921368 CN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H20FNO2/c1-21-7-5-13-9-14(23-8-6-20)11-15-18(13)16(21)10-12-3-2-4-17(22)19(12)15/h2-4,9,11,16,22H,5-8,10H2,1H3/t16-/m1/s1 FOMVFMMGQCMSQQ-MRXNPFEDSA-N 50336864 (R)-2-(2-fluoroethoxy)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL1672313 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53317727 125086966 CHEMBL1672313 ZINC66098525 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921415 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 98 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921418 CCCN1CCc2cc(F)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H20FNO2/c1-2-6-21-7-5-12-8-13(20)10-14-17(12)15(21)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,22-23H,2,5-7,9H2,1H3/t15-/m1/s1 TVIUJNLDORXPPC-OAHLLOKOSA-N 50013061 (R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL106622 D(2) dopamine receptor Rattus norvegicus 1800 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013061&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131213 103925284 CHEMBL106622 ZINC26841490 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921419 CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C20H23NO2/c1-3-8-21-9-7-14-10-15(23-2)12-16-19(14)17(21)11-13-5-4-6-18(22)20(13)16/h4-6,10,12,17,22H,3,7-9,11H2,1-2H3/t17-/m1/s1 PGKMOUOGPCFQTK-QGZVFWFLSA-N 50336856 (R)-(-)-N-propyl-2-methoxy-11-hydroxynoraporphine::(R)-2-methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::2-methoxy-11-hydroxy-N-propylnoraporphine::CHEMBL405345 D(2) dopamine receptor Rattus norvegicus 1400 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24800688 125086958 CHEMBL405345 ZINC29136057 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921420 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m1/s1 WZJSIHGOLMMBAL-MRXNPFEDSA-N 84636 CHEMBL27559::NPA-11-OH-R,(+) D(2) dopamine receptor Rattus norvegicus 1410 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333842 136350736 CHEMBL27559 ZINC05833984 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921421 Oc1cccc2C[C@H]3N(CCCF)CCc4cccc(c34)-c12 InChI=1S/C19H20FNO/c20-9-3-10-21-11-8-13-4-1-6-15-18(13)16(21)12-14-5-2-7-17(22)19(14)15/h1-2,4-7,16,22H,3,8-12H2/t16-/m1/s1 VAURMGBDDSMOJD-MRXNPFEDSA-N 50336857 11-hydroxy-N-(3-fluoropropyl)aporphine::CHEMBL1672302 D(2) dopamine receptor Rattus norvegicus 860 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53320353 125086959 CHEMBL1672302 ZINC66103689 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921422 CCCN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C22H26FNO3/c1-2-8-24-9-6-15-11-16(27-10-3-7-23)13-17-20(15)18(24)12-14-4-5-19(25)22(26)21(14)17/h4-5,11,13,18,25-26H,2-3,6-10,12H2,1H3/t18-/m1/s1 RONFPASSWXANLI-GOSISDBHSA-N 50336852 (R)-2-(3-fluoropropoxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL1672303 D(2) dopamine receptor Rattus norvegicus 3000 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53322769 125086954 CHEMBL1672303 ZINC66074305 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921423 CCCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C21H24FNO3/c1-2-7-23-8-5-14-10-15(26-9-6-22)12-16-19(14)17(23)11-13-3-4-18(24)21(25)20(13)16/h3-4,10,12,17,24-25H,2,5-9,11H2,1H3/t17-/m1/s1 BVBIAGFWBHXIBM-QGZVFWFLSA-N 50336853 (R)-2-(2-fluoroethoxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL1672304 D(2) dopamine receptor Rattus norvegicus 990 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939845 125086955 CHEMBL1672304 ZINC66075719 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921424 CCN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C21H24FNO3/c1-2-23-8-6-14-10-15(26-9-3-7-22)12-16-19(14)17(23)11-13-4-5-18(24)21(25)20(13)16/h4-5,10,12,17,24-25H,2-3,6-9,11H2,1H3/t17-/m1/s1 WFXYNLKNMYICFR-QGZVFWFLSA-N 50336854 CHEMBL1672305::N-ethyl-2-fluoropropanoxy catecholaporphine D(2) dopamine receptor Rattus norvegicus 1600 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53326670 125086956 CHEMBL1672305 ZINC66074306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921425 CCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H22FNO3/c1-2-22-7-5-13-9-14(25-8-6-21)11-15-18(13)16(22)10-12-3-4-17(23)20(24)19(12)15/h3-4,9,11,16,23-24H,2,5-8,10H2,1H3/t16-/m1/s1 XPFXYWKICZQNES-MRXNPFEDSA-N 50336855 (R)-6-ethyl-2-(2-fluoroethoxy)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL1672306 D(2) dopamine receptor Rattus norvegicus 2400 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939846 125086957 CHEMBL1672306 ZINC66074307 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921426 CN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H22FNO3/c1-22-7-5-13-9-14(25-8-2-6-21)11-15-18(13)16(22)10-12-3-4-17(23)20(24)19(12)15/h3-4,9,11,16,23-24H,2,5-8,10H2,1H3/t16-/m1/s1 SMRWXTZCUTYMQO-MRXNPFEDSA-N 50336858 2-fluoropropanoxy catechol aporphine::CHEMBL1672307 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53322729 125086960 CHEMBL1672307 ZINC66074308 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921427 CN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H20FNO3/c1-21-6-4-12-8-13(24-7-5-20)10-14-17(12)15(21)9-11-2-3-16(22)19(23)18(11)14/h2-3,8,10,15,22-23H,4-7,9H2,1H3/t15-/m1/s1 MMZBXOUZUBNDST-OAHLLOKOSA-N 50336859 (R)-2-(2-fluoroethoxy)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL1672308 D(2) dopamine receptor Rattus norvegicus 620 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53317511 125086961 CHEMBL1672308 ZINC66074309 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921428 CCCN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C22H26FNO2/c1-2-9-24-10-7-16-12-17(26-11-4-8-23)14-18-21(16)19(24)13-15-5-3-6-20(25)22(15)18/h3,5-6,12,14,19,25H,2,4,7-11,13H2,1H3/t19-/m1/s1 FVKWMLJXSQTSBS-LJQANCHMSA-N 50336860 CHEMBL1672309::N-propyl-2-fluoropropanoxy-11-monohydroxy aporphine D(2) dopamine receptor Rattus norvegicus 490 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336860&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939977 125086962 CHEMBL1672309 ZINC66074347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921429 CCCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C21H24FNO2/c1-2-8-23-9-6-15-11-16(25-10-7-22)13-17-20(15)18(23)12-14-4-3-5-19(24)21(14)17/h3-5,11,13,18,24H,2,6-10,12H2,1H3/t18-/m1/s1 SWSVYEJPIAYSGL-GOSISDBHSA-N 50336861 CHEMBL1672310::N-propyl-2-fluoroethoxy-11-monohydroxy aporphine D(2) dopamine receptor Rattus norvegicus 56 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336861&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939978 125086963 CHEMBL1672310 ZINC66077822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921430 CCN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C21H24FNO2/c1-2-23-9-7-15-11-16(25-10-4-8-22)13-17-20(15)18(23)12-14-5-3-6-19(24)21(14)17/h3,5-6,11,13,18,24H,2,4,7-10,12H2,1H3/t18-/m1/s1 LODBNYQJHVOXNX-GOSISDBHSA-N 50336862 CHEMBL1672311::N-ethyl-2-fluoropropanoxy-11-monohydroxy aporphine D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336862&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939979 125086964 CHEMBL1672311 ZINC66077823 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921431 CCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C20H22FNO2/c1-2-22-8-6-14-10-15(24-9-7-21)12-16-19(14)17(22)11-13-4-3-5-18(23)20(13)16/h3-5,10,12,17,23H,2,6-9,11H2,1H3/t17-/m1/s1 ZAJYDMAAHSFWGH-QGZVFWFLSA-N 50336863 (R)-6-ethyl-2-(2-fluoroethoxy)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL1672312 D(2) dopamine receptor Rattus norvegicus 750 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336863&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939980 125086965 CHEMBL1672312 ZINC66098523 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921432 CN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H20FNO2/c1-21-7-5-13-9-14(23-8-6-20)11-15-18(13)16(21)10-12-3-2-4-17(22)19(12)15/h2-4,9,11,16,22H,5-8,10H2,1H3/t16-/m1/s1 FOMVFMMGQCMSQQ-MRXNPFEDSA-N 50336864 (R)-2-(2-fluoroethoxy)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL1672313 D(2) dopamine receptor Rattus norvegicus 480 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336864&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53317727 125086966 CHEMBL1672313 ZINC66098525 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921433 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921434 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 0.18 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921435 CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H23NO3/c1-3-7-21-8-6-13-9-14(24-2)11-15-18(13)16(21)10-12-4-5-17(22)20(23)19(12)15/h4-5,9,11,16,22-23H,3,6-8,10H2,1-2H3/t16-/m1/s1 WNNMRMNAGNMVEW-MRXNPFEDSA-N 50010692 (R)-(-)-2-methoxy-N-npropylnorapomorphine::(R)-2-methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53294 D(2) dopamine receptor Rattus norvegicus 5.1 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130907 103923438 CHEMBL53294 ZINC00011666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921436 CCCN1CCc2cc(F)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H20FNO2/c1-2-6-21-7-5-12-8-13(20)10-14-17(12)15(21)9-11-3-4-16(22)19(23)18(11)14/h3-4,8,10,15,22-23H,2,5-7,9H2,1H3/t15-/m1/s1 TVIUJNLDORXPPC-OAHLLOKOSA-N 50013061 (R)-2-fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Fluoro-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL106622 D(2) dopamine receptor Rattus norvegicus 2.7 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013061&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131213 103925284 CHEMBL106622 ZINC26841490 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921437 CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C20H23NO2/c1-3-8-21-9-7-14-10-15(23-2)12-16-19(14)17(21)11-13-5-4-6-18(22)20(13)16/h4-6,10,12,17,22H,3,7-9,11H2,1-2H3/t17-/m1/s1 PGKMOUOGPCFQTK-QGZVFWFLSA-N 50336856 (R)-(-)-N-propyl-2-methoxy-11-hydroxynoraporphine::(R)-2-methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::2-methoxy-11-hydroxy-N-propylnoraporphine::CHEMBL405345 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24800688 125086958 CHEMBL405345 ZINC29136057 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921438 CCCN1CCc2cccc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C19H21NO/c1-2-10-20-11-9-13-5-3-7-15-18(13)16(20)12-14-6-4-8-17(21)19(14)15/h3-8,16,21H,2,9-12H2,1H3/t16-/m1/s1 WZJSIHGOLMMBAL-MRXNPFEDSA-N 84636 CHEMBL27559::NPA-11-OH-R,(+) D(2) dopamine receptor Rattus norvegicus 4.9 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333842 136350736 CHEMBL27559 ZINC05833984 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921439 Oc1cccc2C[C@H]3N(CCCF)CCc4cccc(c34)-c12 InChI=1S/C19H20FNO/c20-9-3-10-21-11-8-13-4-1-6-15-18(13)16(21)12-14-5-2-7-17(22)19(14)15/h1-2,4-7,16,22H,3,8-12H2/t16-/m1/s1 VAURMGBDDSMOJD-MRXNPFEDSA-N 50336857 11-hydroxy-N-(3-fluoropropyl)aporphine::CHEMBL1672302 D(2) dopamine receptor Rattus norvegicus 6.9 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53320353 125086959 CHEMBL1672302 ZINC66103689 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921440 CCCN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C22H26FNO3/c1-2-8-24-9-6-15-11-16(27-10-3-7-23)13-17-20(15)18(24)12-14-4-5-19(25)22(26)21(14)17/h4-5,11,13,18,25-26H,2-3,6-10,12H2,1H3/t18-/m1/s1 RONFPASSWXANLI-GOSISDBHSA-N 50336852 (R)-2-(3-fluoropropoxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL1672303 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53322769 125086954 CHEMBL1672303 ZINC66074305 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921441 CCCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C21H24FNO3/c1-2-7-23-8-5-14-10-15(26-9-6-22)12-16-19(14)17(23)11-13-3-4-18(24)21(25)20(13)16/h3-4,10,12,17,24-25H,2,5-9,11H2,1H3/t17-/m1/s1 BVBIAGFWBHXIBM-QGZVFWFLSA-N 50336853 (R)-2-(2-fluoroethoxy)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL1672304 D(2) dopamine receptor Rattus norvegicus 3.7 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939845 125086955 CHEMBL1672304 ZINC66075719 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921442 CCN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C21H24FNO3/c1-2-23-8-6-14-10-15(26-9-3-7-22)12-16-19(14)17(23)11-13-4-5-18(24)21(25)20(13)16/h4-5,10,12,17,24-25H,2-3,6-9,11H2,1H3/t17-/m1/s1 WFXYNLKNMYICFR-QGZVFWFLSA-N 50336854 CHEMBL1672305::N-ethyl-2-fluoropropanoxy catecholaporphine D(2) dopamine receptor Rattus norvegicus 6.1 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53326670 125086956 CHEMBL1672305 ZINC66074306 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921443 CCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H22FNO3/c1-2-22-7-5-13-9-14(25-8-6-21)11-15-18(13)16(22)10-12-3-4-17(23)20(24)19(12)15/h3-4,9,11,16,23-24H,2,5-8,10H2,1H3/t16-/m1/s1 XPFXYWKICZQNES-MRXNPFEDSA-N 50336855 (R)-6-ethyl-2-(2-fluoroethoxy)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL1672306 D(2) dopamine receptor Rattus norvegicus 2.5 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939846 125086957 CHEMBL1672306 ZINC66074307 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921444 CN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H22FNO3/c1-22-7-5-13-9-14(25-8-2-6-21)11-15-18(13)16(22)10-12-3-4-17(23)20(24)19(12)15/h3-4,9,11,16,23-24H,2,5-8,10H2,1H3/t16-/m1/s1 SMRWXTZCUTYMQO-MRXNPFEDSA-N 50336858 2-fluoropropanoxy catechol aporphine::CHEMBL1672307 D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53322729 125086960 CHEMBL1672307 ZINC66074308 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921445 CN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H20FNO3/c1-21-6-4-12-8-13(24-7-5-20)10-14-17(12)15(21)9-11-2-3-16(22)19(23)18(11)14/h2-3,8,10,15,22-23H,4-7,9H2,1H3/t15-/m1/s1 MMZBXOUZUBNDST-OAHLLOKOSA-N 50336859 (R)-2-(2-fluoroethoxy)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL1672308 D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 53317511 125086961 CHEMBL1672308 ZINC66074309 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921446 CCCN1CCc2cc(OCCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 InChI=1S/C22H26FNO2/c1-2-9-24-10-7-16-12-17(26-11-4-8-23)14-18-21(16)19(24)13-15-5-3-6-20(25)22(15)18/h3,5-6,12,14,19,25H,2,4,7-11,13H2,1H3/t19-/m1/s1 FVKWMLJXSQTSBS-LJQANCHMSA-N 50336860 CHEMBL1672309::N-propyl-2-fluoropropanoxy-11-monohydroxy aporphine D(2) dopamine receptor Rattus norvegicus 0.54 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336860&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 52939977 125086962 CHEMBL1672309 ZINC66074347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921416 CCCN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C19H21NO2/c1-2-9-20-10-8-12-4-3-5-14-17(12)15(20)11-13-6-7-16(21)19(22)18(13)14/h3-7,15,21-22H,2,8-11H2,1H3/t15-/m1/s1 BTGAJCKRXPNBFI-OAHLLOKOSA-N 50007422 (+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(-)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium::(R)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium(R(-)NPA)::6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL225230::CHEMBL538542::N-propylapomorphine::N-propylnorapomorphine-(+)::N-propylnorapomorphine-(-) D(2) dopamine receptor Rattus norvegicus 54 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007422 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007422&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 167715 103920697 CHEMBL225230CHEMBL538542 969 ZINC02539817 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50921417 CCCN1CCc2cc(OC)cc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C20H23NO3/c1-3-7-21-8-6-13-9-14(24-2)11-15-18(13)16(21)10-12-4-5-17(22)20(23)19(12)15/h4-5,9,11,16,22-23H,3,6-8,10H2,1-2H3/t16-/m1/s1 WNNMRMNAGNMVEW-MRXNPFEDSA-N 50010692 (R)-(-)-2-methoxy-N-npropylnorapomorphine::(R)-2-methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::2-Methoxy-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53294 D(2) dopamine receptor Rattus norvegicus 810 ChEMBL 10.1021/ml1001689 10.7270/Q2Z89DF8 21666830 Sromek, AW; Si, YG; Zhang, T; George, SR; Seeman, P; Neumeyer, JL Harvard Medical School http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010692&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 130907 103923438 CHEMBL53294 ZINC00011666 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923780 COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C20H23ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1 PMQONYDCPOSURY-HZPDHXFCSA-N 50354109 CHEMBL1836050 D(2) dopamine receptor Rattus norvegicus 44000 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354109&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56672418 136360795 CHEMBL1836050 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923781 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923782 OCCOCCN1CCN(CC1)C1=Nc2ccccc2Sc2ccccc12 InChI=1S/C21H25N3O2S/c25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21/h1-8,25H,9-16H2 URKOMYMAXPYINW-UHFFFAOYSA-N 50095890 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol::2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-1-yl)ethoxy]ethanol::CHEMBL716::QUETIAPINE D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50095890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50095890&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5002 103993497 8707 CHEMBL716 DB01224 50 C07397 ZINC19632628 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923783 CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m1/s1 ZZJYIKPMDIWRSN-TZBSWOFLSA-N 50366495 (+)butaclamol::CHEMBL1255588 D(2) dopamine receptor Rattus norvegicus 0.5 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 37461 160845597 73298 CHEMBL1255588 ZINC01481744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923799 COc1ccccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C20H24N2O3/c1-24-19-7-3-2-6-18(19)20(23)21-14-11-15-8-9-16(12-14)22(15)13-17-5-4-10-25-17/h2-7,10,14-16H,8-9,11-13H2,1H3,(H,21,23)/t15-,16-/m1/s1 CFSCHFKQAOMNAI-HZPDHXFCSA-N 50354090 CHEMBL1836043 D(2) dopamine receptor Rattus norvegicus 1000 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354090&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56679119 136360776 CHEMBL1836043 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923800 COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c1OC InChI=1S/C21H26N2O4/c1-25-19-7-3-6-18(20(19)26-2)21(24)22-14-11-15-8-9-16(12-14)23(15)13-17-5-4-10-27-17/h3-7,10,14-16H,8-9,11-13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1 HKJYGPPOMQQLIZ-HZPDHXFCSA-N 50354091 CHEMBL1836044 D(2) dopamine receptor Rattus norvegicus 26.3 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354091&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56679120 136360777 CHEMBL1836044 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923801 COc1ccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c(OC)c1 InChI=1S/C21H26N2O4/c1-25-17-7-8-19(20(12-17)26-2)21(24)22-14-10-15-5-6-16(11-14)23(15)13-18-4-3-9-27-18/h3-4,7-9,12,14-16H,5-6,10-11,13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1 GMOVHKOPYDCRKI-HZPDHXFCSA-N 50354092 CHEMBL1836045 D(2) dopamine receptor Rattus norvegicus 652.5 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354092&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56675797 136360778 CHEMBL1836045 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923802 COc1ccc(OC)c(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C21H26N2O4/c1-25-17-7-8-20(26-2)19(12-17)21(24)22-14-10-15-5-6-16(11-14)23(15)13-18-4-3-9-27-18/h3-4,7-9,12,14-16H,5-6,10-11,13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1 IIBZGDZRQNVEKX-HZPDHXFCSA-N 50354093 CHEMBL1836046 D(2) dopamine receptor Rattus norvegicus 1100 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354093&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56658573 136360779 CHEMBL1836046 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923803 COc1ccc(cc1OC)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C21H26N2O4/c1-25-19-8-5-14(10-20(19)26-2)21(24)22-15-11-16-6-7-17(12-15)23(16)13-18-4-3-9-27-18/h3-5,8-10,15-17H,6-7,11-13H2,1-2H3,(H,22,24)/t16-,17-/m1/s1 FDPJUCRBSXQXFO-IAGOWNOFSA-N 50354106 CHEMBL1836047 D(2) dopamine receptor Rattus norvegicus 68800 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354106&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56662016 136360792 CHEMBL1836047 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923804 COc1cc(OC)cc(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C21H26N2O4/c1-25-19-8-14(9-20(12-19)26-2)21(24)22-15-10-16-5-6-17(11-15)23(16)13-18-4-3-7-27-18/h3-4,7-9,12,15-17H,5-6,10-11,13H2,1-2H3,(H,22,24)/t16-,17-/m1/s1 AZXKWXPHQAJYEW-IAGOWNOFSA-N 50354107 CHEMBL1836048::cid_653771 D(2) dopamine receptor Rattus norvegicus 13200 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 51014484 136360793 CHEMBL1836048 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923805 COc1cc(cc(OC)c1OC)C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C22H28N2O5/c1-26-19-9-14(10-20(27-2)21(19)28-3)22(25)23-15-11-16-6-7-17(12-15)24(16)13-18-5-4-8-29-18/h4-5,8-10,15-17H,6-7,11-13H2,1-3H3,(H,23,25)/t16-,17-/m1/s1 MYJZXJWVQVVYHK-IAGOWNOFSA-N 50354108 CHEMBL1836049 D(2) dopamine receptor Rattus norvegicus 52200 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354108&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56675798 136360794 CHEMBL1836049 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923806 COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C20H23ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1 PMQONYDCPOSURY-HZPDHXFCSA-N 50354109 CHEMBL1836050 D(2) dopamine receptor Rattus norvegicus 218.2 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354109&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56672418 136360795 CHEMBL1836050 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923807 COc1ccc(F)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C20H23FN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1 SKJONSWSIFDKAN-HZPDHXFCSA-N 50354110 CHEMBL1836051 D(2) dopamine receptor Rattus norvegicus 507.4 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354110&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56682414 136360796 CHEMBL1836051 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923808 COc1cc(Cl)ccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C20H23ClN2O3/c1-25-19-9-13(21)4-7-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h2-4,7-9,14-16H,5-6,10-12H2,1H3,(H,22,24)/t15-,16-/m1/s1 PGXSSBALVLNDFL-HZPDHXFCSA-N 50354111 CHEMBL1836052 D(2) dopamine receptor Rattus norvegicus 174.3 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354111&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56679121 136360797 CHEMBL1836052 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923809 [O-][N+](=O)c1cc(Cl)ccc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C19H20ClN3O4/c20-12-3-6-17(18(8-12)23(25)26)19(24)21-13-9-14-4-5-15(10-13)22(14)11-16-2-1-7-27-16/h1-3,6-8,13-15H,4-5,9-11H2,(H,21,24)/t14-,15-/m1/s1 IHFKUUHNHKRBIO-HUUCEWRRSA-N 50354112 CHEMBL1836053 D(2) dopamine receptor Rattus norvegicus 19000 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354112&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56682415 136360798 CHEMBL1836053 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923810 O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1)c1cccc2ccccc12 InChI=1S/C23H24N2O2/c26-23(22-9-3-6-16-5-1-2-8-21(16)22)24-17-13-18-10-11-19(14-17)25(18)15-20-7-4-12-27-20/h1-9,12,17-19H,10-11,13-15H2,(H,24,26)/t18-,19-/m1/s1 ZDGGIHYVFAXCLZ-RTBURBONSA-N 50354113 CHEMBL1836055 D(2) dopamine receptor Rattus norvegicus 66700 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354113&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56662017 136360799 CHEMBL1836055 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923811 O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1)c1ccc2ccccc2c1 InChI=1S/C23H24N2O2/c26-23(18-8-7-16-4-1-2-5-17(16)12-18)24-19-13-20-9-10-21(14-19)25(20)15-22-6-3-11-27-22/h1-8,11-12,19-21H,9-10,13-15H2,(H,24,26)/t20-,21-/m1/s1 IILPLAOABJATAZ-NHCUHLMSSA-N 50354114 CHEMBL1836056 D(2) dopamine receptor Rattus norvegicus 202.5 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354114&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56682416 136360800 CHEMBL1836056 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923812 O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1ccccc1 InChI=1S/C19H26N2O2/c22-19(14-5-2-1-3-6-14)20-15-11-16-8-9-17(12-15)21(16)13-18-7-4-10-23-18/h1-3,5-6,15-18H,4,7-13H2,(H,20,22)/t16-,17-,18?/m1/s1 MKDFWWSSCBFLQD-OWZOALSMSA-N 50354094 CHEMBL1836057 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354094&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56675799 136360780 CHEMBL1836057 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923813 COc1ccc(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 InChI=1S/C20H27ClN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h4,7,9,14-17H,2-3,5-6,8,10-12H2,1H3,(H,22,24)/t15-,16-,17?/m1/s1 RIEMXJMKVGFKQM-YNPPLXCJSA-N 50354096 CHEMBL1836059 D(2) dopamine receptor Rattus norvegicus 2400 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354096&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56658574 136360782 CHEMBL1836059 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923814 COc1ccc(F)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 InChI=1S/C20H27FN2O3/c1-25-19-7-4-13(21)9-18(19)20(24)22-14-10-15-5-6-16(11-14)23(15)12-17-3-2-8-26-17/h4,7,9,14-17H,2-3,5-6,8,10-12H2,1H3,(H,22,24)/t15-,16-,17?/m1/s1 RMYJHKWCNASDMS-YNPPLXCJSA-N 50354097 CHEMBL1836060 D(2) dopamine receptor Rattus norvegicus 12400 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354097&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56672419 136360783 CHEMBL1836060 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923815 COc1cc(N)c(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 InChI=1S/C20H28ClN3O3/c1-26-19-10-18(22)17(21)9-16(19)20(25)23-12-7-13-4-5-14(8-12)24(13)11-15-3-2-6-27-15/h9-10,12-15H,2-8,11,22H2,1H3,(H,23,25)/t13-,14-,15?/m1/s1 ZCAJSDJHROYKRV-GRKKQISMSA-N 50354098 CHEMBL1836061 D(2) dopamine receptor Rattus norvegicus 103.3 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354098&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56665508 136360784 CHEMBL1836061 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923816 O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1cccc2ccccc12 InChI=1S/C23H28N2O2/c26-23(22-9-3-6-16-5-1-2-8-21(16)22)24-17-13-18-10-11-19(14-17)25(18)15-20-7-4-12-27-20/h1-3,5-6,8-9,17-20H,4,7,10-15H2,(H,24,26)/t18-,19-,20?/m1/s1 AVTQCLISYQTDGJ-LEAGNCFPSA-N 50354099 CHEMBL1836104 D(2) dopamine receptor Rattus norvegicus 4000 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354099&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56671946 136360785 CHEMBL1836104 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923817 O=C(NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1)c1ccc2ccccc2c1 InChI=1S/C23H28N2O2/c26-23(18-8-7-16-4-1-2-5-17(16)12-18)24-19-13-20-9-10-21(14-19)25(20)15-22-6-3-11-27-22/h1-2,4-5,7-8,12,19-22H,3,6,9-11,13-15H2,(H,24,26)/t20-,21-,22?/m1/s1 VONACKKTKYGFTQ-JAZPPYFYSA-N 50354100 CHEMBL1836105 D(2) dopamine receptor Rattus norvegicus 1200 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354100&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56675319 136360786 CHEMBL1836105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923818 O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccccc1)c1cccc2ccccc12 InChI=1S/C25H26N2O/c28-25(24-12-6-10-19-9-4-5-11-23(19)24)26-20-15-21-13-14-22(16-20)27(21)17-18-7-2-1-3-8-18/h1-12,20-22H,13-17H2,(H,26,28)/t21-,22-/m1/s1 XVAVJGIUMJWANK-FGZHOGPDSA-N 50354101 CHEMBL1836106 D(2) dopamine receptor Rattus norvegicus 2900 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354101&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56671947 136360787 CHEMBL1836106 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923819 O=C(NC1C[C@H]2CC[C@H](C1)N2Cc1ccccc1)c1ccc2ccccc2c1 InChI=1S/C25H26N2O/c28-25(21-11-10-19-8-4-5-9-20(19)14-21)26-22-15-23-12-13-24(16-22)27(23)17-18-6-2-1-3-7-18/h1-11,14,22-24H,12-13,15-17H2,(H,26,28)/t23-,24-/m1/s1 SZQSNCKURPPYDK-DNQXCXABSA-N 50354102 CHEMBL1836107 D(2) dopamine receptor Rattus norvegicus 82.4 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354102&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56675320 136360788 CHEMBL1836107 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923820 COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccccn2)c1OC InChI=1S/C22H27N3O3/c1-27-20-8-5-7-19(21(20)28-2)22(26)24-16-12-17-9-10-18(13-16)25(17)14-15-6-3-4-11-23-15/h3-8,11,16-18H,9-10,12-14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1 WDGKRJOWJWPMDB-QZTJIDSGSA-N 50354103 CHEMBL1836108 D(2) dopamine receptor Rattus norvegicus 9.3 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354103&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56658066 136360789 CHEMBL1836108 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923821 COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccncc2)c1OC InChI=1S/C22H27N3O3/c1-27-20-5-3-4-19(21(20)28-2)22(26)24-16-12-17-6-7-18(13-16)25(17)14-15-8-10-23-11-9-15/h3-5,8-11,16-18H,6-7,12-14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1 YQAAQEWGUXUHKQ-QZTJIDSGSA-N 50354105 CHEMBL1836110 D(2) dopamine receptor Rattus norvegicus 28.3 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354105&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56661578 136360791 CHEMBL1836110 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923822 COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2ccco2)c1OC InChI=1S/C21H26N2O4/c1-25-19-7-3-6-18(20(19)26-2)21(24)22-14-11-15-8-9-16(12-14)23(15)13-17-5-4-10-27-17/h3-7,10,14-16H,8-9,11-13H2,1-2H3,(H,22,24)/t15-,16-/m1/s1 HKJYGPPOMQQLIZ-HZPDHXFCSA-N 50354091 CHEMBL1836044 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354091&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56679120 136360777 CHEMBL1836044 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923869 COc1cccc(c1)C(=O)NC1C[C@H]2CC[C@H](C1)N2CC1CCCO1 InChI=1S/C20H28N2O3/c1-24-18-5-2-4-14(10-18)20(23)21-15-11-16-7-8-17(12-15)22(16)13-19-6-3-9-25-19/h2,4-5,10,15-17,19H,3,6-9,11-13H2,1H3,(H,21,23)/t16-,17-,19?/m1/s1 CXDYANQSQGATOW-QNZPCDNOSA-N 50354095 CHEMBL1836058 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354095&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56662018 136360781 CHEMBL1836058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923871 COc1cc(N)c(Cl)cc1C(=O)NC1C[C@H]2CC[C@H](C1)N2Cc1ccco1 InChI=1S/C20H24ClN3O3/c1-26-19-10-18(22)17(21)9-16(19)20(25)23-12-7-13-4-5-14(8-12)24(13)11-15-3-2-6-27-15/h2-3,6,9-10,12-14H,4-5,7-8,11,22H2,1H3,(H,23,25)/t13-,14-/m1/s1 ALWXXPBCPWBWHH-ZIAGYGMSSA-N 50354115 CHEMBL1836054 D(2) dopamine receptor Rattus norvegicus 18.2 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354115&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56668935 136360801 CHEMBL1836054 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50923872 COc1cccc(C(=O)NC2C[C@H]3CC[C@H](C2)N3Cc2cccnc2)c1OC InChI=1S/C22H27N3O3/c1-27-20-7-3-6-19(21(20)28-2)22(26)24-16-11-17-8-9-18(12-16)25(17)14-15-5-4-10-23-13-15/h3-7,10,13,16-18H,8-9,11-12,14H2,1-2H3,(H,24,26)/t17-,18-/m1/s1 WLWMCLIVTDROGV-QZTJIDSGSA-N 50354104 CHEMBL1836109 D(2) dopamine receptor Rattus norvegicus 11.5 ChEMBL 10.1016/j.ejmech.2011.07.022 10.7270/Q2Z0395D 21816515 Slowinski, T; Stefanowicz, J; Dawidowski, M; Kleps, J; Czuczwar, S; Andres-Mach, M; Luszczki, JJ; Nowak, G; Stachowicz, K; Szewczyk, B; Slawinska, A; Mazurek, AP; Mazurek, A; Plucinski, F; Wolska, I; Herold, F Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50354104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50354104&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56675321 136360790 CHEMBL1836109 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931881 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cc(cc(c2)C(F)(F)F)C#N)CC1 InChI=1S/C22H29F3N4O/c1-16(30)27-20-4-2-17(3-5-20)6-7-28-8-10-29(11-9-28)21-13-18(15-26)12-19(14-21)22(23,24)25/h12-14,17,20H,2-11H2,1H3,(H,27,30)/t17-,20- IRUJTELKGAIRCF-IRJFHVNHSA-N 50382291 CHEMBL2024508 D(2) dopamine receptor Rattus norvegicus 143 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382291&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70683580 160861374 CHEMBL2024508 ZINC84615571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931882 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cc(cc(c2)C(F)(F)F)C#N)CC1 InChI=1S/C21H29F3N4O2S/c1-31(29,30)26-19-4-2-16(3-5-19)6-7-27-8-10-28(11-9-27)20-13-17(15-25)12-18(14-20)21(22,23)24/h12-14,16,19,26H,2-11H2,1H3/t16-,19- ITEOHYCIFGQEBA-RUCARUNLSA-N 50382292 CHEMBL2024509 D(2) dopamine receptor Rattus norvegicus 135 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382292&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70692034 160861375 CHEMBL2024509 ZINC84615573 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931883 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(c2)C(F)(F)F)CC1 InChI=1S/C21H30F3N3O/c1-16(28)25-19-7-5-17(6-8-19)9-10-26-11-13-27(14-12-26)20-4-2-3-18(15-20)21(22,23)24/h2-4,15,17,19H,5-14H2,1H3,(H,25,28)/t17-,19- ODNRLPHKNBBCKK-UAPYVXQJSA-N 50382293 CHEMBL2024506 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70681458 160861376 CHEMBL2024506 ZINC84604989 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931884 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(c2)C(F)(F)F)CC1 InChI=1S/C20H30F3N3O2S/c1-29(27,28)24-18-7-5-16(6-8-18)9-10-25-11-13-26(14-12-25)19-4-2-3-17(15-19)20(21,22)23/h2-4,15-16,18,24H,5-14H2,1H3/t16-,18- WXOFSOBWUSNIIJ-SAABIXHNSA-N 50382294 CHEMBL2024510 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382294 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382294&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70696190 160861377 CHEMBL2024510 ZINC84615576 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931885 CC(=O)N[C@H]1CC[C@H](CCN2CCC(Cc3cccc(c3)C(F)(F)F)CC2)CC1 InChI=1S/C23H33F3N2O/c1-17(29)27-22-7-5-18(6-8-22)9-12-28-13-10-19(11-14-28)15-20-3-2-4-21(16-20)23(24,25)26/h2-4,16,18-19,22H,5-15H2,1H3,(H,27,29)/t18-,22- ACKBCTLAXFJWPZ-LBZQVFOQSA-N 50382295 CHEMBL2024507 D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382295&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70696189 160861378 CHEMBL2024507 ZINC84618284 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931886 CC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)Oc2cccc(c2)C(F)(F)F)CC1 InChI=1S/C22H31F3N2O2/c1-16(28)26-19-7-5-17(6-8-19)9-12-27-13-10-20(11-14-27)29-21-4-2-3-18(15-21)22(23,24)25/h2-4,15,17,19-20H,5-14H2,1H3,(H,26,28)/t17-,19- KXXWXEBOCLSFEB-UAPYVXQJSA-N 50382296 CHEMBL2021954 D(2) dopamine receptor Rattus norvegicus 85 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382296&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70689874 160861379 CHEMBL2021954 ZINC84615579 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931887 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(Cc3cccc(c3)C(F)(F)F)CC2)CC1 InChI=1S/C21H32F3N3O2S/c1-30(28,29)25-20-7-5-17(6-8-20)9-10-26-11-13-27(14-12-26)16-18-3-2-4-19(15-18)21(22,23)24/h2-4,15,17,20,25H,5-14,16H2,1H3/t17-,20- TWTKUCSHDGYPHU-IRJFHVNHSA-N 50382297 CHEMBL2024511 D(2) dopamine receptor Rattus norvegicus 158 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382297&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70696191 160861380 CHEMBL2024511 ZINC84615581 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931888 CCOC(=O)N[C@H]1CC[C@H](CCN2CCN(Cc3cccc(c3)C(F)(F)F)CC2)CC1 InChI=1S/C23H34F3N3O2/c1-2-31-22(30)27-21-8-6-18(7-9-21)10-11-28-12-14-29(15-13-28)17-19-4-3-5-20(16-19)23(24,25)26/h3-5,16,18,21H,2,6-15,17H2,1H3,(H,27,30)/t18-,21- IQAAMALQRNVNHH-XGAFWQRZSA-N 50382298 CHEMBL2024512 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382298&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70683581 160861381 CHEMBL2024512 ZINC84615898 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931889 CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C20H29Cl2N3O/c1-15(26)23-17-7-5-16(6-8-17)9-10-24-11-13-25(14-12-24)19-4-2-3-18(21)20(19)22/h2-4,16-17H,5-14H2,1H3,(H,23,26)/t16-,17- DIRKDNYXNPECEK-QAQDUYKDSA-N 50382300 CHEMBL2024514 D(2) dopamine receptor Rattus norvegicus 2.3 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382300 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382300&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70683582 160861383 CHEMBL2024514 ZINC84615902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931890 CS(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C19H29Cl2N3O2S/c1-27(25,26)22-16-7-5-15(6-8-16)9-10-23-11-13-24(14-12-23)18-4-2-3-17(20)19(18)21/h2-4,15-16,22H,5-14H2,1H3/t15-,16- MEEYWSYFAMXWHM-WKILWMFISA-N 50382301 CHEMBL2024515 D(2) dopamine receptor Rattus norvegicus 5.4 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382301&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70683583 160861384 CHEMBL2024515 ZINC84617160 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931891 CCC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C21H31Cl2N3O/c1-2-20(27)24-17-8-6-16(7-9-17)10-11-25-12-14-26(15-13-25)19-5-3-4-18(22)21(19)23/h3-5,16-17H,2,6-15H2,1H3,(H,24,27)/t16-,17- MXIKBLWWYRRRQW-QAQDUYKDSA-N 50382302 CHEMBL2024516 D(2) dopamine receptor Rattus norvegicus 7.1 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382302&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70696192 160861385 CHEMBL2024516 ZINC84615587 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931892 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,6-15H2,1-2H3,(H,24,28)/t16-,17- KPWSJANDNDDRMB-QAQDUYKDSA-N 50382290 CARIPRAZINE HYDROCHLORIDE::RGH-188 HCL D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 7RU 7VOD 11154555 160861373 DB06016 ZINC38309313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931893 CCNC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C21H32Cl2N4O/c1-2-24-21(28)25-17-8-6-16(7-9-17)10-11-26-12-14-27(15-13-26)19-5-3-4-18(22)20(19)23/h3-5,16-17H,2,6-15H2,1H3,(H2,24,25,28)/t16-,17- QNTHRQYZEIGUHC-QAQDUYKDSA-N 50382313 CHEMBL2024518 D(2) dopamine receptor Rattus norvegicus 16.9 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382313&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11441732 160861396 CHEMBL2024518 ZINC06745880 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931894 CCN(CC)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C23H36Cl2N4O/c1-3-28(4-2)23(30)26-19-10-8-18(9-11-19)12-13-27-14-16-29(17-15-27)21-7-5-6-20(24)22(21)25/h5-7,18-19H,3-4,8-17H2,1-2H3,(H,26,30)/t18-,19- CLYLEOXSUSFWBW-WGSAOQKQSA-N 50382303 CHEMBL2024519 D(2) dopamine receptor Rattus norvegicus 42.9 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382303 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382303&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11259580 160861386 CHEMBL2024519 ZINC84619884 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931895 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1 InChI=1S/C21H34N4O/c1-23(2)21(26)22-19-10-8-18(9-11-19)12-13-24-14-16-25(17-15-24)20-6-4-3-5-7-20/h3-7,18-19H,8-17H2,1-2H3,(H,22,26)/t18-,19- JLNHYHADCFCEMM-WGSAOQKQSA-N 50382305 CHEMBL2024521 D(2) dopamine receptor Rattus norvegicus 94 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382305&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70685688 160861388 CHEMBL2024521 ZINC84597055 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931896 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2Cl)CC1 InChI=1S/C21H33ClN4O/c1-24(2)21(27)23-18-9-7-17(8-10-18)11-12-25-13-15-26(16-14-25)20-6-4-3-5-19(20)22/h3-6,17-18H,7-16H2,1-2H3,(H,23,27)/t17-,18- XDNZBXLKJAIAEY-IYARVYRRSA-N 50382306 CHEMBL2024522 D(2) dopamine receptor Rattus norvegicus 19.8 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382306 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382306&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70687842 160861389 CHEMBL2024522 ZINC84597056 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931897 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2)CC1 InChI=1S/C21H33ClN4O/c1-24(2)21(27)23-19-8-6-17(7-9-19)10-11-25-12-14-26(15-13-25)20-5-3-4-18(22)16-20/h3-5,16-17,19H,6-15H2,1-2H3,(H,23,27)/t17-,19- YSBQONTVTTYPQN-UAPYVXQJSA-N 50382307 CHEMBL2024523 D(2) dopamine receptor Rattus norvegicus 53.4 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382307 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382307&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70694072 160861390 CHEMBL2024523 ZINC84635945 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931898 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccc(Cl)cc2)CC1 InChI=1S/C21H33ClN4O/c1-24(2)21(27)23-19-7-3-17(4-8-19)11-12-25-13-15-26(16-14-25)20-9-5-18(22)6-10-20/h5-6,9-10,17,19H,3-4,7-8,11-16H2,1-2H3,(H,23,27)/t17-,19- UKTPIKKOBBTSDN-UAPYVXQJSA-N 50382308 CHEMBL2024524 D(2) dopamine receptor Rattus norvegicus 392 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382308 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382308&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70692035 160861391 CHEMBL2024524 ZINC84597057 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931899 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccc(Cl)cc2Cl)CC1 InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-18-6-3-16(4-7-18)9-10-26-11-13-27(14-12-26)20-8-5-17(22)15-19(20)23/h5,8,15-16,18H,3-4,6-7,9-14H2,1-2H3,(H,24,28)/t16-,18- JLOYRWNVJPTEPM-SAABIXHNSA-N 50382309 CHEMBL2024525 D(2) dopamine receptor Rattus norvegicus 106 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382309&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70683584 160861392 CHEMBL2024525 ZINC84597058 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931900 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cc(Cl)ccc2Cl)CC1 InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-18-6-3-16(4-7-18)9-10-26-11-13-27(14-12-26)20-15-17(22)5-8-19(20)23/h5,8,15-16,18H,3-4,6-7,9-14H2,1-2H3,(H,24,28)/t16-,18- ZOFQSWIVLXQEOJ-SAABIXHNSA-N 50382310 CHEMBL2024675 D(2) dopamine receptor Rattus norvegicus 8.2 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382310&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70687847 160861393 CHEMBL2024675 ZINC84632691 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931901 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-17-5-3-16(4-6-17)9-10-26-11-13-27(14-12-26)18-7-8-19(22)20(23)15-18/h7-8,15-17H,3-6,9-14H2,1-2H3,(H,24,28)/t16-,17- FUTLCWMQHXZFBX-QAQDUYKDSA-N 50382311 CHEMBL2024676 D(2) dopamine receptor Rattus norvegicus 110 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382311&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70685697 160861394 CHEMBL2024676 ZINC84632693 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931902 CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cc(Cl)cc(Cl)c2)CC1 InChI=1S/C21H32Cl2N4O/c1-25(2)21(28)24-19-5-3-16(4-6-19)7-8-26-9-11-27(12-10-26)20-14-17(22)13-18(23)15-20/h13-16,19H,3-12H2,1-2H3,(H,24,28)/t16-,19- HEXCASWJNLTLBO-RUCARUNLSA-N 50382312 CHEMBL2024677 D(2) dopamine receptor Rattus norvegicus 20.2 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382312&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70683590 160861395 CHEMBL2024677 ZINC84632695 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931903 NC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C19H28Cl2N4O/c20-17-6-5-16(13-18(17)21)25-11-9-24(10-12-25)8-7-14-1-3-15(4-2-14)23-19(22)26/h5-6,13-15H,1-4,7-12H2,(H3,22,23,26)/t14-,15- PYTQKUTVNQGNKV-SHTZXODSSA-N 50382304 CHEMBL2024520 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382304&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70681460 160861387 CHEMBL2024520 ZINC84619887 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50931905 FC(F)(F)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1 InChI=1S/C20H26Cl2F3N3O/c21-16-2-1-3-17(18(16)22)28-12-10-27(11-13-28)9-8-14-4-6-15(7-5-14)26-19(29)20(23,24)25/h1-3,14-15H,4-13H2,(H,26,29)/t14-,15- JTCQWBUUHDIJSE-SHTZXODSSA-N 50382299 CHEMBL2024513 D(2) dopamine receptor Rattus norvegicus 5.9 ChEMBL 10.1016/j.bmcl.2012.03.104 10.7270/Q2ZW1MZN 22537450 Agai-Csongor, E; Domany, G; Nogradi, K; Galambos, J; Vago, I; Keseru, GM; Greiner, I; Laszlovszky, I; Gere, A; Schmidt, E; Kiss, B; Vastag, M; Tihanyi, K; Saghy, K; Laszy, J; Gyertyan, I; Zajer-Balazs, M; Gemesi, L; Kapas, M; Szombathelyi, Z Gedeon Richter Plc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 70681459 160861382 CHEMBL2024513 ZINC84615900 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955530 CCCN(CCC)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1 MDBWEQVKJDMEMK-AWEZNQCLSA-N 50115277 (2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2R,3S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-(-)-5-hydroxy-2-(N,N-di-n-propylamino)tetralin::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol.HCl::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL269004 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11299620 104009254 CHEMBL269004 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955531 CCCN(CCN1CCN(CC1)c1ccccc1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C25H35N3O/c1-2-13-27(23-11-12-24-21(20-23)7-6-10-25(24)29)17-14-26-15-18-28(19-16-26)22-8-4-3-5-9-22/h3-10,23,29H,2,11-20H2,1H3/t23-/m0/s1 ACDYFMOSSUKHJD-QHCPKHFHSA-N 50273938 (-)-(S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::(S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::CHEMBL457024::D-237 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273938&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24754542 104117901 CHEMBL457024 ZINC28964118 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955532 CCCN(CCN1CCN(CC1)c1nccc2ccccc12)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C25H34N6S/c1-2-11-30(20-7-8-22-23(18-20)32-25(26)28-22)15-12-29-13-16-31(17-14-29)24-21-6-4-3-5-19(21)9-10-27-24/h3-6,9-10,20H,2,7-8,11-18H2,1H3,(H2,26,28)/t20-/m0/s1 SNMHDHJEXUFVCO-FQEVSTJZSA-N 50303791 (-)-(S)-N6-(2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine::CHEMBL571992 D(2) dopamine receptor Rattus norvegicus 269 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50303791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50303791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45486330 104158152 CHEMBL571992 ZINC45283305 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955533 CCCN(CCN1CCN(CC1)c1ccc(cc1)-c1ccccc1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C28H37N5S/c1-2-14-32(25-12-13-26-27(21-25)34-28(29)30-26)18-15-31-16-19-33(20-17-31)24-10-8-23(9-11-24)22-6-4-3-5-7-22/h3-11,25H,2,12-21H2,1H3,(H2,29,30)/t25-/m0/s1 YDLWLYDTYNHXBM-VWLOTQADSA-N 50273996 (S)-N*6*-[2-(4-Biphenyl-4-yl-piperazin-1-yl)-ethyl]-N*6*-propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine::(S)-N6-(2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine::CHEMBL514885::D-264 D(2) dopamine receptor Rattus norvegicus 264 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273996&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24866612 104117939 CHEMBL514885 ZINC40379927 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955534 CCCN(CCN1CCN(Cc2ccc3[nH]ccc3c2)CC1)C1CCc2c(O)cccc2C1 InChI=1S/C28H38N4O/c1-2-12-32(25-7-8-26-23(20-25)4-3-5-28(26)33)18-17-30-13-15-31(16-14-30)21-22-6-9-27-24(19-22)10-11-29-27/h3-6,9-11,19,25,29,33H,2,7-8,12-18,20-21H2,1H3 NKHABRQZQARSOA-UHFFFAOYSA-N 50392118 CHEMBL2152629 D(2) dopamine receptor Rattus norvegicus 269 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165952 163341142 CHEMBL2152629 ZINC95580059 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955535 CCCN(CCN1CCN(Cc2cc3ccccc3[nH]2)CC1)C1CCc2c(O)cccc2C1 InChI=1S/C28H38N4O/c1-2-12-32(25-10-11-26-22(20-25)7-5-9-28(26)33)18-17-30-13-15-31(16-14-30)21-24-19-23-6-3-4-8-27(23)29-24/h3-9,19,25,29,33H,2,10-18,20-21H2,1H3 ZJEOOWHLNQLCFZ-UHFFFAOYSA-N 50392119 CHEMBL2152630 D(2) dopamine receptor Rattus norvegicus 183 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392119&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165953 163341143 CHEMBL2152630 ZINC95574130 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955536 CCCN(CCN1CCN(Cc2c[nH]c3ccccc23)CC1)C1CCc2c(O)cccc2C1 InChI=1S/C28H38N4O/c1-2-12-32(24-10-11-26-22(19-24)6-5-9-28(26)33)18-17-30-13-15-31(16-14-30)21-23-20-29-27-8-4-3-7-25(23)27/h3-9,20,24,29,33H,2,10-19,21H2,1H3 UHRDDHPBSKWWGI-UHFFFAOYSA-N 50392120 CHEMBL2152631 D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60166101 163341144 CHEMBL2152631 ZINC95575444 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955537 CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1)C1CCc2nc(N)sc2C1 InChI=1S/C24H34N6S/c1-2-9-29(20-4-6-22-23(17-20)31-24(25)27-22)13-10-28-11-14-30(15-12-28)19-3-5-21-18(16-19)7-8-26-21/h3,5,7-8,16,20,26H,2,4,6,9-15,17H2,1H3,(H2,25,27) YQJXEYCSOAXZLM-UHFFFAOYSA-N 50392121 CHEMBL2152632::US10874669, Compound (+-)-10 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60148498 163341145 CHEMBL2152632 ZINC95572455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955538 CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C24H34N6S/c1-2-9-29(20-4-6-22-23(17-20)31-24(25)27-22)13-10-28-11-14-30(15-12-28)19-3-5-21-18(16-19)7-8-26-21/h3,5,7-8,16,20,26H,2,4,6,9-15,17H2,1H3,(H2,25,27)/t20-/m0/s1 YQJXEYCSOAXZLM-FQEVSTJZSA-N 50392122 CHEMBL2152633::US10874669, Compound (+)-10 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392122&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60148497 163341146 CHEMBL2152633 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955539 CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1)[C@@H]1CCc2nc(N)sc2C1 InChI=1S/C24H34N6S/c1-2-9-29(20-4-6-22-23(17-20)31-24(25)27-22)13-10-28-11-14-30(15-12-28)19-3-5-21-18(16-19)7-8-26-21/h3,5,7-8,16,20,26H,2,4,6,9-15,17H2,1H3,(H2,25,27)/t20-/m1/s1 YQJXEYCSOAXZLM-HXUWFJFHSA-N 50392123 CHEMBL2152634::US10874669, Compound (-)-10 D(2) dopamine receptor Rattus norvegicus 134 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392123&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60166104 163341147 CHEMBL2152634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955540 CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1)C1CCc2c(O)cccc2C1 InChI=1S/C27H36N4O/c1-2-12-30(23-6-8-25-21(19-23)4-3-5-27(25)32)16-13-29-14-17-31(18-15-29)24-7-9-26-22(20-24)10-11-28-26/h3-5,7,9-11,20,23,28,32H,2,6,8,12-19H2,1H3 GZIUGYGQNRNHAD-UHFFFAOYSA-N 50392124 CHEMBL2152745 D(2) dopamine receptor Rattus norvegicus 76 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392124&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165388 163341148 CHEMBL2152745 ZINC95574731 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955541 CCCN(CCN1CCN(CC1)C(=O)c1cc2ccccc2[nH]1)C1CCc2nc(N)sc2C1 InChI=1S/C25H34N6OS/c1-2-9-30(19-7-8-21-23(17-19)33-25(26)28-21)13-10-29-11-14-31(15-12-29)24(32)22-16-18-5-3-4-6-20(18)27-22/h3-6,16,19,27H,2,7-15,17H2,1H3,(H2,26,28) CPWJJWMVFFZCGJ-UHFFFAOYSA-N 50392125 CHEMBL2152746 D(2) dopamine receptor Rattus norvegicus 852 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392125&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165801 163341149 CHEMBL2152746 ZINC95576089 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955542 CCCN(CCN1CCN(CC1)C(=O)c1cc2ccccc2[nH]1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C25H34N6OS/c1-2-9-30(19-7-8-21-23(17-19)33-25(26)28-21)13-10-29-11-14-31(15-12-29)24(32)22-16-18-5-3-4-6-20(18)27-22/h3-6,16,19,27H,2,7-15,17H2,1H3,(H2,26,28)/t19-/m0/s1 CPWJJWMVFFZCGJ-IBGZPJMESA-N 50392126 CHEMBL2152747 D(2) dopamine receptor Rattus norvegicus 1073 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392126&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60148494 163341150 CHEMBL2152747 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955543 CCCN(CCN1CCN(CC1)C(=O)c1cc2ccccc2[nH]1)[C@@H]1CCc2nc(N)sc2C1 InChI=1S/C25H34N6OS/c1-2-9-30(19-7-8-21-23(17-19)33-25(26)28-21)13-10-29-11-14-31(15-12-29)24(32)22-16-18-5-3-4-6-20(18)27-22/h3-6,16,19,27H,2,7-15,17H2,1H3,(H2,26,28)/t19-/m1/s1 CPWJJWMVFFZCGJ-LJQANCHMSA-N 50392127 CHEMBL2152748 D(2) dopamine receptor Rattus norvegicus 2558 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392127&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60166234 163341151 CHEMBL2152748 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955544 CCCN(CCCN1CCN(CC1)C(=O)c1cc2ccccc2[nH]1)C1CCc2nc(N)sc2C1 InChI=1S/C26H36N6OS/c1-2-10-31(20-8-9-22-24(18-20)34-26(27)29-22)12-5-11-30-13-15-32(16-14-30)25(33)23-17-19-6-3-4-7-21(19)28-23/h3-4,6-7,17,20,28H,2,5,8-16,18H2,1H3,(H2,27,29) YXOJSZBNFOORSL-UHFFFAOYSA-N 50392128 CHEMBL2152749 D(2) dopamine receptor Rattus norvegicus 928 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392128&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165802 163341152 CHEMBL2152749 ZINC95574829 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955545 CCCN(CCCCN1CCN(CC1)C(=O)c1cc2ccccc2[nH]1)C1CCc2nc(N)sc2C1 InChI=1S/C27H38N6OS/c1-2-11-32(21-9-10-23-25(19-21)35-27(28)30-23)13-6-5-12-31-14-16-33(17-15-31)26(34)24-18-20-7-3-4-8-22(20)29-24/h3-4,7-8,18,21,29H,2,5-6,9-17,19H2,1H3,(H2,28,30) HFGNKYGWNOCWPA-UHFFFAOYSA-N 50392129 CHEMBL2152750 D(2) dopamine receptor Rattus norvegicus 531 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165803 163341153 CHEMBL2152750 ZINC95577237 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955546 CCCN(CCN1CCN(CC1)C(=O)c1c[nH]c2ccccc12)C1CCc2nc(N)sc2C1 InChI=1S/C25H34N6OS/c1-2-9-30(18-7-8-22-23(16-18)33-25(26)28-22)13-10-29-11-14-31(15-12-29)24(32)20-17-27-21-6-4-3-5-19(20)21/h3-6,17-18,27H,2,7-16H2,1H3,(H2,26,28) SJIPQSFBLAVVRK-UHFFFAOYSA-N 50392130 CHEMBL2152751 D(2) dopamine receptor Rattus norvegicus 1503 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392130&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165804 163341154 CHEMBL2152751 ZINC95571936 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955547 CCCN(CCN1CCN(CC1)C(=O)c1c[nH]c2ccccc12)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C25H34N6OS/c1-2-9-30(18-7-8-22-23(16-18)33-25(26)28-22)13-10-29-11-14-31(15-12-29)24(32)20-17-27-21-6-4-3-5-19(20)21/h3-6,17-18,27H,2,7-16H2,1H3,(H2,26,28)/t18-/m0/s1 SJIPQSFBLAVVRK-SFHVURJKSA-N 50392131 CHEMBL2152752 D(2) dopamine receptor Rattus norvegicus 902 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392131&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60148496 163341155 CHEMBL2152752 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955548 CCCN(CCN1CCN(CC1)C(=O)c1c[nH]c2ccccc12)[C@@H]1CCc2nc(N)sc2C1 InChI=1S/C25H34N6OS/c1-2-9-30(18-7-8-22-23(16-18)33-25(26)28-22)13-10-29-11-14-31(15-12-29)24(32)20-17-27-21-6-4-3-5-19(20)21/h3-6,17-18,27H,2,7-16H2,1H3,(H2,26,28)/t18-/m1/s1 SJIPQSFBLAVVRK-GOSISDBHSA-N 50392132 CHEMBL2152753 D(2) dopamine receptor Rattus norvegicus 1316 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392132&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60166354 163341156 CHEMBL2152753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955549 CCCN(CCN1CCN(CC1)C(=O)c1ccc2[nH]ccc2c1)C1CCc2nc(N)sc2C1 InChI=1S/C25H34N6OS/c1-2-9-30(20-4-6-22-23(17-20)33-25(26)28-22)13-10-29-11-14-31(15-12-29)24(32)19-3-5-21-18(16-19)7-8-27-21/h3,5,7-8,16,20,27H,2,4,6,9-15,17H2,1H3,(H2,26,28) OXCQNGTWPIHFHI-UHFFFAOYSA-N 50392133 CHEMBL2152754 D(2) dopamine receptor Rattus norvegicus 1243 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392133&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165948 163341157 CHEMBL2152754 ZINC95575983 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955550 CCCN(CCN1CCN(CC1)C(=O)c1ccc2[nH]ccc2c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C25H34N6OS/c1-2-9-30(20-4-6-22-23(17-20)33-25(26)28-22)13-10-29-11-14-31(15-12-29)24(32)19-3-5-21-18(16-19)7-8-27-21/h3,5,7-8,16,20,27H,2,4,6,9-15,17H2,1H3,(H2,26,28)/t20-/m0/s1 OXCQNGTWPIHFHI-FQEVSTJZSA-N 50392134 CHEMBL2152755 D(2) dopamine receptor Rattus norvegicus 1031 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392134&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60148495 163341158 CHEMBL2152755 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955551 CCCN(CCN1CCN(CC1)C(=O)c1ccc2[nH]ccc2c1)[C@@H]1CCc2nc(N)sc2C1 InChI=1S/C25H34N6OS/c1-2-9-30(20-4-6-22-23(17-20)33-25(26)28-22)13-10-29-11-14-31(15-12-29)24(32)19-3-5-21-18(16-19)7-8-27-21/h3,5,7-8,16,20,27H,2,4,6,9-15,17H2,1H3,(H2,26,28)/t20-/m1/s1 OXCQNGTWPIHFHI-HXUWFJFHSA-N 50392135 CHEMBL2152756 D(2) dopamine receptor Rattus norvegicus 2626 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392135&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60166355 163341159 CHEMBL2152756 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955552 CCCN(CCN1CCN(CC1)C(=O)c1c[nH]c2ccc(O)cc12)C1CCc2nc(N)sc2C1 InChI=1S/C25H34N6O2S/c1-2-7-30(17-3-5-22-23(14-17)34-25(26)28-22)11-8-29-9-12-31(13-10-29)24(33)20-16-27-21-6-4-18(32)15-19(20)21/h4,6,15-17,27,32H,2-3,5,7-14H2,1H3,(H2,26,28) WKYPBWJCTXFZPX-UHFFFAOYSA-N 50392136 CHEMBL2152757 D(2) dopamine receptor Rattus norvegicus 1079 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392136&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165950 163341160 CHEMBL2152757 ZINC95576030 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50955553 CCCN(CCN1CCN(Cc2ccc3[nH]ccc3c2)CC1)C1CCc2nc(N)sc2C1 InChI=1S/C25H36N6S/c1-2-9-31(21-4-6-23-24(17-21)32-25(26)28-23)15-14-29-10-12-30(13-11-29)18-19-3-5-22-20(16-19)7-8-27-22/h3,5,7-8,16,21,27H,2,4,6,9-15,17-18H2,1H3,(H2,26,28) YZWDIMZALKFOTP-UHFFFAOYSA-N 50392137 CHEMBL2152758 D(2) dopamine receptor Rattus norvegicus 132 ChEMBL 10.1021/jm300268s 10.7270/Q2NC629F 22642365 Johnson, M; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392137&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60165951 163341161 CHEMBL2152758 ZINC95579983 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50986111 Cc1cc(=O)oc2cc(OCCCN3CCN(CC3)c3ccccc3)ccc12 InChI=1S/C23H26N2O3/c1-18-16-23(26)28-22-17-20(8-9-21(18)22)27-15-5-10-24-11-13-25(14-12-24)19-6-3-2-4-7-19/h2-4,6-9,16-17H,5,10-15H2,1H3 ZYBLSQVXWVJACW-UHFFFAOYSA-N 50073272 4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-chromen-2-one::CHEMBL52096 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1016/s0960-894x(02)00933-2 10.7270/Q2T43V8H 12482418 Gonzalez-Gomez, JC; Santana, L; Uriarte, E; Brea, J; Villazon, M; Loza, MI; De Luca, M; Rivas, ME; Montenegro, GY; Fontenla, JA University of Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073272&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10317514 103966699 CHEMBL52096 ZINC13486988 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50986112 COc1cc(=O)oc2cc(OCCCN3CCN(CC3)c3ncccn3)ccc12 InChI=1S/C21H24N4O4/c1-27-18-15-20(26)29-19-14-16(4-5-17(18)19)28-13-3-8-24-9-11-25(12-10-24)21-22-6-2-7-23-21/h2,4-7,14-15H,3,8-13H2,1H3 RVWBSEDETCKVHN-UHFFFAOYSA-N 50404047 CHEMBL52384 D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1016/s0960-894x(02)00933-2 10.7270/Q2T43V8H 12482418 Gonzalez-Gomez, JC; Santana, L; Uriarte, E; Brea, J; Villazon, M; Loza, MI; De Luca, M; Rivas, ME; Montenegro, GY; Fontenla, JA University of Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50404047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50404047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44294988 163353071 CHEMBL52384 ZINC13486995 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50986113 COc1cc(=O)oc2cc(OCCCN3CCN(CC3)c3ccccc3)ccc12 InChI=1S/C23H26N2O4/c1-27-21-17-23(26)29-22-16-19(8-9-20(21)22)28-15-5-10-24-11-13-25(14-12-24)18-6-3-2-4-7-18/h2-4,6-9,16-17H,5,10-15H2,1H3 LMTBBOFCAUHANH-UHFFFAOYSA-N 50404048 CHEMBL48194 D(2) dopamine receptor Rattus norvegicus 562 ChEMBL 10.1016/s0960-894x(02)00933-2 10.7270/Q2T43V8H 12482418 Gonzalez-Gomez, JC; Santana, L; Uriarte, E; Brea, J; Villazon, M; Loza, MI; De Luca, M; Rivas, ME; Montenegro, GY; Fontenla, JA University of Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50404048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50404048&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44294973 163353072 CHEMBL48194 ZINC13486989 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50986119 COc1cc(=O)oc2cc(OCCCN3CCN(CC3)c3ccccn3)ccc12 InChI=1S/C22H25N3O4/c1-27-19-16-22(26)29-20-15-17(6-7-18(19)20)28-14-4-9-24-10-12-25(13-11-24)21-5-2-3-8-23-21/h2-3,5-8,15-16H,4,9-14H2,1H3 SYOCPHHLXVQWHC-UHFFFAOYSA-N 50404049 CHEMBL48205 D(2) dopamine receptor Rattus norvegicus 129 ChEMBL 10.1016/s0960-894x(02)00933-2 10.7270/Q2T43V8H 12482418 Gonzalez-Gomez, JC; Santana, L; Uriarte, E; Brea, J; Villazon, M; Loza, MI; De Luca, M; Rivas, ME; Montenegro, GY; Fontenla, JA University of Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50404049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50404049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44294972 163353073 CHEMBL48205 ZINC13486993 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50986120 Cc1cc(=O)oc2cc(OCCCN3CCN(CC3)c3ncccn3)ccc12 InChI=1S/C21H24N4O3/c1-16-14-20(26)28-19-15-17(4-5-18(16)19)27-13-3-8-24-9-11-25(12-10-24)21-22-6-2-7-23-21/h2,4-7,14-15H,3,8-13H2,1H3 FUEJWMOQCYOKMY-UHFFFAOYSA-N 50404051 CHEMBL265805 D(2) dopamine receptor Rattus norvegicus 324 ChEMBL 10.1016/s0960-894x(02)00933-2 10.7270/Q2T43V8H 12482418 Gonzalez-Gomez, JC; Santana, L; Uriarte, E; Brea, J; Villazon, M; Loza, MI; De Luca, M; Rivas, ME; Montenegro, GY; Fontenla, JA University of Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50404051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50404051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44294687 163353075 CHEMBL265805 ZINC13486994 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50986125 Cc1cc(=O)oc2cc(OCCCN3CCN(CC3)c3ccccn3)ccc12 InChI=1S/C22H25N3O3/c1-17-15-22(26)28-20-16-18(6-7-19(17)20)27-14-4-9-24-10-12-25(13-11-24)21-5-2-3-8-23-21/h2-3,5-8,15-16H,4,9-14H2,1H3 YJWDNOICKTZNCG-UHFFFAOYSA-N 50404052 CHEMBL51681 D(2) dopamine receptor Rattus norvegicus 81 ChEMBL 10.1016/s0960-894x(02)00933-2 10.7270/Q2T43V8H 12482418 Gonzalez-Gomez, JC; Santana, L; Uriarte, E; Brea, J; Villazon, M; Loza, MI; De Luca, M; Rivas, ME; Montenegro, GY; Fontenla, JA University of Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50404052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50404052&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44294683 163353076 CHEMBL51681 ZINC13486992 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50986126 COc1ccccc1N1CCN(CCCOc2ccc3c(C)cc(=O)oc3c2)CC1 InChI=1S/C24H28N2O4/c1-18-16-24(27)30-23-17-19(8-9-20(18)23)29-15-5-10-25-11-13-26(14-12-25)21-6-3-4-7-22(21)28-2/h3-4,6-9,16-17H,5,10-15H2,1-2H3 WYYRWPAVRAAIOL-UHFFFAOYSA-N 50404053 CHEMBL51767 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/s0960-894x(02)00933-2 10.7270/Q2T43V8H 12482418 Gonzalez-Gomez, JC; Santana, L; Uriarte, E; Brea, J; Villazon, M; Loza, MI; De Luca, M; Rivas, ME; Montenegro, GY; Fontenla, JA University of Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50404053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50404053&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10250895 163353077 CHEMBL51767 ZINC13486990 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50986130 COc1ccccc1N1CCN(CCCOc2ccc3c(OC)cc(=O)oc3c2)CC1 InChI=1S/C24H28N2O5/c1-28-21-7-4-3-6-20(21)26-13-11-25(12-14-26)10-5-15-30-18-8-9-19-22(29-2)17-24(27)31-23(19)16-18/h3-4,6-9,16-17H,5,10-15H2,1-2H3 XTQWEIZIKPNRTR-UHFFFAOYSA-N 50404050 CHEMBL298108 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1016/s0960-894x(02)00933-2 10.7270/Q2T43V8H 12482418 Gonzalez-Gomez, JC; Santana, L; Uriarte, E; Brea, J; Villazon, M; Loza, MI; De Luca, M; Rivas, ME; Montenegro, GY; Fontenla, JA University of Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50404050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50404050&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44294991 163353074 CHEMBL298108 ZINC13486991 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50986132 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 3 ChEMBL 10.1016/s0960-894x(02)00933-2 10.7270/Q2T43V8H 12482418 Gonzalez-Gomez, JC; Santana, L; Uriarte, E; Brea, J; Villazon, M; Loza, MI; De Luca, M; Rivas, ME; Montenegro, GY; Fontenla, JA University of Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50007810 COc1cc2nc(nc(N)c2cc1OC)N(C)CCCCCCN(C)C(=O)c1ccco1 InChI=1S/C23H31N5O4/c1-27(22(29)18-10-9-13-32-18)11-7-5-6-8-12-28(2)23-25-17-15-20(31-4)19(30-3)14-16(17)21(24)26-23/h9-10,13-15H,5-8,11-12H2,1-4H3,(H2,24,25,26) ILQHFOKYOSAZBJ-UHFFFAOYSA-N 50403647 CHEMBL27013 D(2) dopamine receptor Rattus norvegicus 2344 ChEMBL 10.1016/s0960-894x(98)00217-0 10.7270/Q2V69KRR 9871765 Minarini, A; Budriesi, R; Chiarini, A; Leonardi, A; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14423371 163352671 CHEMBL27013 ZINC01542216 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572673 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) IENZQIKPVFGBNW-UHFFFAOYSA-N 29568 CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1016/s0960-894x(98)00217-0 10.7270/Q2V69KRR 9871765 Minarini, A; Budriesi, R; Chiarini, A; Leonardi, A; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search XRA 3OWX 4893 81054997 8364 CHEMBL2 DB00457 503 C07368 ZINC00601304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572676 COc1cc2nc(nc(N)c2cc1OC)N1CCN([C@H]2CCCC[C@@H]12)C(=O)c1ccco1 InChI=1S/C23H27N5O4/c1-30-19-12-14-15(13-20(19)31-2)25-23(26-21(14)24)28-10-9-27(16-6-3-4-7-17(16)28)22(29)18-8-5-11-32-18/h5,8,11-13,16-17H,3-4,6-7,9-10H2,1-2H3,(H2,24,25,26)/t16-,17+/m0/s1 XBRXTUGRUXGBPX-DLBZAZTESA-N 50403649 CYCLAZOSIN D(2) dopamine receptor Rattus norvegicus 8318 ChEMBL 10.1016/s0960-894x(98)00217-0 10.7270/Q2V69KRR 9871765 Minarini, A; Budriesi, R; Chiarini, A; Leonardi, A; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search T0B 7B6W 132266 163352673 63937 ZINC02385764 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50572682 COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3 AYYCFGDXLUPJAQ-UHFFFAOYSA-N 50026917 8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione::8-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione::8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione::8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione(BMY-7378)::BMY 7378::BMY-7378::CHEMBL1256934::CHEMBL13647::CHEMBL543741 D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1016/s0960-894x(98)00217-0 10.7270/Q2V69KRR 9871765 Minarini, A; Budriesi, R; Chiarini, A; Leonardi, A; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2419 103936501 CHEMBL543741CHEMBL1256934CHEMBL13647 9 ZINC53064442 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50001442 Nc1nc2CC[C@@H](Cc2s1)N1CCN(CC1)c1ccccn1 InChI=1S/C16H21N5S/c17-16-19-13-5-4-12(11-14(13)22-16)20-7-9-21(10-8-20)15-3-1-2-6-18-15/h1-3,6,12H,4-5,7-11H2,(H2,17,19)/t12-/m0/s1 FPNSOJRXMGJRFL-LBPRGKRZSA-N 50279867 (S)-6-(4-Pyridin-2-yl-piperazin-1-yl)-4,5,6,7-tetrahydro-benzothiazol-2-ylamine::CHEMBL56584 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1016/S0960-894X(00)80249-8 10.7270/Q2ZC83BV Jaen, JC; Caprathe, BW; Wise, LD; Smith, SJ; Pugsley, TA; Heffner, TG; Meltzer, LT TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15681504 104121571 CHEMBL56584 ZINC29554524 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50001445 Nc1nc2CC[C@H](Cc2s1)N1CCN(CC1)c1ccccn1 InChI=1S/C16H21N5S/c17-16-19-13-5-4-12(11-14(13)22-16)20-7-9-21(10-8-20)15-3-1-2-6-18-15/h1-3,6,12H,4-5,7-11H2,(H2,17,19)/t12-/m1/s1 FPNSOJRXMGJRFL-GFCCVEGCSA-N 50279866 (R)-6-(4-Pyridin-2-yl-piperazin-1-yl)-4,5,6,7-tetrahydro-benzothiazol-2-ylamine::CHEMBL58265 D(2) dopamine receptor Rattus norvegicus 440 ChEMBL 10.1016/S0960-894X(00)80249-8 10.7270/Q2ZC83BV Jaen, JC; Caprathe, BW; Wise, LD; Smith, SJ; Pugsley, TA; Heffner, TG; Meltzer, LT TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15681503 104121570 CHEMBL58265 ZINC29554520 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50001446 Nc1nc2CC[C@H](Cc2s1)N1CCN(CC1)c1ccccn1 InChI=1S/C16H21N5S/c17-16-19-13-5-4-12(11-14(13)22-16)20-7-9-21(10-8-20)15-3-1-2-6-18-15/h1-3,6,12H,4-5,7-11H2,(H2,17,19)/t12-/m1/s1 FPNSOJRXMGJRFL-GFCCVEGCSA-N 50279866 (R)-6-(4-Pyridin-2-yl-piperazin-1-yl)-4,5,6,7-tetrahydro-benzothiazol-2-ylamine::CHEMBL58265 D(2) dopamine receptor Rattus norvegicus 105 ChEMBL 10.1016/S0960-894X(00)80249-8 10.7270/Q2ZC83BV Jaen, JC; Caprathe, BW; Wise, LD; Smith, SJ; Pugsley, TA; Heffner, TG; Meltzer, LT TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15681503 104121570 CHEMBL58265 ZINC29554520 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50556079 Nc1nc2CC[C@H](Cc2s1)N1CCN(CC1)c1ccccn1 InChI=1S/C16H21N5S/c17-16-19-13-5-4-12(11-14(13)22-16)20-7-9-21(10-8-20)15-3-1-2-6-18-15/h1-3,6,12H,4-5,7-11H2,(H2,17,19)/t12-/m1/s1 FPNSOJRXMGJRFL-GFCCVEGCSA-N 50279866 (R)-6-(4-Pyridin-2-yl-piperazin-1-yl)-4,5,6,7-tetrahydro-benzothiazol-2-ylamine::CHEMBL58265 D(2) dopamine receptor Rattus norvegicus 320 ChEMBL 10.1016/S0960-894X(00)80249-8 10.7270/Q2ZC83BV Jaen, JC; Caprathe, BW; Wise, LD; Smith, SJ; Pugsley, TA; Heffner, TG; Meltzer, LT TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15681503 104121570 CHEMBL58265 ZINC29554520 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50556081 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 1.7 ChEMBL 10.1016/S0960-894X(00)80249-8 10.7270/Q2ZC83BV Jaen, JC; Caprathe, BW; Wise, LD; Smith, SJ; Pugsley, TA; Heffner, TG; Meltzer, LT TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976800 CCCN(CCCCCCCCCc1ccccc1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C28H41NO/c1-2-21-29(26-19-20-27-25(23-26)17-13-18-28(27)30)22-12-7-5-3-4-6-9-14-24-15-10-8-11-16-24/h8,10-11,13,15-18,26,30H,2-7,9,12,14,19-23H2,1H3/t26-/m0/s1 HVFVTDPHUINJDO-SANMLTNESA-N 50400591 CHEMBL2206268 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71463108 163349615 CHEMBL2206268 ZINC95559419 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976801 CCCCCCCCCN(CCC)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C22H37NO/c1-3-5-6-7-8-9-10-17-23(16-4-2)20-14-15-21-19(18-20)12-11-13-22(21)24/h11-13,20,24H,3-10,14-18H2,1-2H3/t20-/m0/s1 WFWBTUDCRNGUJQ-FQEVSTJZSA-N 50400592 CHEMBL2203317 D(2) dopamine receptor Rattus norvegicus 69 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400592&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71459661 163349616 CHEMBL2203317 ZINC95559933 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976802 CCCN(CCCCCCCCCCCCCCN(CCC)[C@H]1CCc2c(O)cccc2C1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C40H64N2O2/c1-3-27-41(35-23-25-37-33(31-35)19-17-21-39(37)43)29-15-13-11-9-7-5-6-8-10-12-14-16-30-42(28-4-2)36-24-26-38-34(32-36)20-18-22-40(38)44/h17-22,35-36,43-44H,3-16,23-32H2,1-2H3/t35-,36-/m0/s1 YOHFJNHKEUZNTC-ZPGRZCPFSA-N 50400593 CHEMBL2206267 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400593&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71463107 163349617 CHEMBL2206267 ZINC95564094 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976803 CCCN(CCCCCCCCCCCCN(CCC)[C@H]1CCc2c(O)cccc2C1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C38H60N2O2/c1-3-25-39(33-21-23-35-31(29-33)17-15-19-37(35)41)27-13-11-9-7-5-6-8-10-12-14-28-40(26-4-2)34-22-24-36-32(30-34)18-16-20-38(36)42/h15-20,33-34,41-42H,3-14,21-30H2,1-2H3/t33-,34-/m0/s1 ZXPLFBMDBNQTIP-HEVIKAOCSA-N 50400594 CHEMBL2206266 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71463106 163349618 CHEMBL2206266 ZINC95560581 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976804 CCCN(CCCCCCCCCCN(CCC)[C@H]1CCc2c(O)cccc2C1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C36H56N2O2/c1-3-23-37(31-19-21-33-29(27-31)15-13-17-35(33)39)25-11-9-7-5-6-8-10-12-26-38(24-4-2)32-20-22-34-30(28-32)16-14-18-36(34)40/h13-18,31-32,39-40H,3-12,19-28H2,1-2H3/t31-,32-/m0/s1 SQYZBSPQNGOKJY-ACHIHNKUSA-N 50400589 CHEMBL2206265 D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400589&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71459660 163349613 CHEMBL2206265 ZINC95560321 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976805 CCCN(CCCCCCCCCN(CCC)[C@H]1CCc2c(O)cccc2C1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C35H54N2O2/c1-3-22-36(30-18-20-32-28(26-30)14-12-16-34(32)38)24-10-8-6-5-7-9-11-25-37(23-4-2)31-19-21-33-29(27-31)15-13-17-35(33)39/h12-17,30-31,38-39H,3-11,18-27H2,1-2H3/t30-,31-/m0/s1 FAUOEZQOXBUMAX-CONSDPRKSA-N 50400590 CHEMBL2206264 D(2) dopamine receptor Rattus norvegicus 2.5 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400590&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71459659 163349614 CHEMBL2206264 ZINC95559929 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976806 CCCN(CCCCCCCN(CCC)[C@H]1CCc2c(O)cccc2C1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C33H50N2O2/c1-3-20-34(28-16-18-30-26(24-28)12-10-14-32(30)36)22-8-6-5-7-9-23-35(21-4-2)29-17-19-31-27(25-29)13-11-15-33(31)37/h10-15,28-29,36-37H,3-9,16-25H2,1-2H3/t28-,29-/m0/s1 CIDCPLKTGCFTOZ-VMPREFPWSA-N 50400595 CHEMBL2206273 D(2) dopamine receptor Rattus norvegicus 3.9 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71459664 163349619 CHEMBL2206273 ZINC95562515 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976807 CCCN(CCCCCCN(CCC)[C@H]1CCc2c(O)cccc2C1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C32H48N2O2/c1-3-19-33(27-15-17-29-25(23-27)11-9-13-31(29)35)21-7-5-6-8-22-34(20-4-2)28-16-18-30-26(24-28)12-10-14-32(30)36/h9-14,27-28,35-36H,3-8,15-24H2,1-2H3/t27-,28-/m0/s1 VXMCESXCRDMCQJ-NSOVKSMOSA-N 50400596 CHEMBL2206272 D(2) dopamine receptor Rattus norvegicus 5.9 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400596&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71454200 163349620 CHEMBL2206272 ZINC95559340 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976808 CCCN(CCCCCN(CCC)[C@H]1CCc2c(O)cccc2C1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C31H46N2O2/c1-3-18-32(26-14-16-28-24(22-26)10-8-12-30(28)34)20-6-5-7-21-33(19-4-2)27-15-17-29-25(23-27)11-9-13-31(29)35/h8-13,26-27,34-35H,3-7,14-23H2,1-2H3/t26-,27-/m0/s1 VVGHVCRBPYKJEP-SVBPBHIXSA-N 50400597 CHEMBL2206271 D(2) dopamine receptor Rattus norvegicus 75 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400597 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400597&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71459663 163349621 CHEMBL2206271 ZINC95562154 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976809 CCCN(CCCCN(CCC)[C@H]1CCc2c(O)cccc2C1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C30H44N2O2/c1-3-17-31(25-13-15-27-23(21-25)9-7-11-29(27)33)19-5-6-20-32(18-4-2)26-14-16-28-24(22-26)10-8-12-30(28)34/h7-12,25-26,33-34H,3-6,13-22H2,1-2H3/t25-,26-/m0/s1 IXVCYXLRBYFANX-UIOOFZCWSA-N 50400598 CHEMBL2206270 D(2) dopamine receptor Rattus norvegicus 70 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400598&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71463109 163349622 CHEMBL2206270 ZINC95562727 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976810 CCCN(CCN(CCC)[C@H]1CCc2c(O)cccc2C1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C28H40N2O2/c1-3-15-29(23-11-13-25-21(19-23)7-5-9-27(25)31)17-18-30(16-4-2)24-12-14-26-22(20-24)8-6-10-28(26)32/h5-10,23-24,31-32H,3-4,11-20H2,1-2H3/t23-,24-/m0/s1 DTBWPACMEMXXSN-ZEQRLZLVSA-N 50400599 CHEMBL2206269 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50400599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50400599&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71459662 163349623 CHEMBL2206269 ZINC95561544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50976811 CCCN(CCC)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1 MDBWEQVKJDMEMK-AWEZNQCLSA-N 50115277 (2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2R,3S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-(-)-5-hydroxy-2-(N,N-di-n-propylamino)tetralin::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol.HCl::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL269004 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1021/ml3002117 10.7270/Q26M3804 23275802 Gogoi, S; Biswas, S; Modi, G; Antonio, T; Reith, ME; Dutta, AK TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11299620 104009254 CHEMBL269004 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032845 CCN1CCC[C@H]1CNC(=O)c1c(O)c(OC)cc(Br)c1OC InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)12(22-2)8-11(17)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 UFZPFNGITSAOBL-JTQLQIEISA-N 50368073 CHEMBL1907690 D(2) dopamine receptor Rattus norvegicus 67 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368073&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668296 160847175 CHEMBL1907690 ZINC34343069 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032849 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032855 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50634693 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.920000 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50634694 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 WGLPSCZHULDZSS-JTQLQIEISA-N 50007517 (S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-5,6-dimethoxybenzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-5,6-dimethoxy-benzamide::CHEMBL76402 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977478 103920792 CHEMBL76402 ZINC03776019 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50985682 CN(C)CCC1CC2N(O1)c1ccccc1Cc1ccccc21 InChI=1S/C20H24N2O/c1-21(2)12-11-17-14-20-18-9-5-3-7-15(18)13-16-8-4-6-10-19(16)22(20)23-17/h3-10,17,20H,11-14H2,1-2H3 SWGWJQBPCJEQJC-UHFFFAOYSA-N 50403957 CHEMBL313189 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1016/s0960-894x(01)00721-1 10.7270/Q23J3F4C 11755364 Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403957&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44461606 163352981 CHEMBL313189 ZINC13436833 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50985721 Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H YNPFMWCWRVTGKJ-UHFFFAOYSA-N 31005 2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine::MIANSERIN HYDROCHLORIDE::MLS000069681::SMR000058472::cid_68551 D(2) dopamine receptor Rattus norvegicus 3548 ChEMBL 10.1016/s0960-894x(01)00721-1 10.7270/Q23J3F4C 11755364 Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31005&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68551 242052839 ZINC00000504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003647 Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 HGEYJZMMUGWEOT-UHFFFAOYSA-N 50002173 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole D(2) dopamine receptor Rattus norvegicus 6 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002173&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 219050 103916479 48558 CHEMBL431367 52 ZINC01548439 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003648 C(CN1CCC(=CC1)c1ccccc1)Cc1c[nH]c2ccccc12 InChI=1S/C22H24N2/c1-2-7-18(8-3-1)19-12-15-24(16-13-19)14-6-9-20-17-23-22-11-5-4-10-21(20)22/h1-5,7-8,10-12,17,23H,6,9,13-16H2 XDNNWNKVOIAXTP-UHFFFAOYSA-N 50002170 3-[3-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-propyl]-1H-indole::CHEMBL131841 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002170&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10089397 103916476 CHEMBL131841 ZINC13728574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003652 Clc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H25ClN2/c24-21-9-10-23-22(16-21)20(17-25-23)8-4-5-13-26-14-11-19(12-15-26)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,25H,4-5,8,12-15H2 WWBXRAAWXACMHT-UHFFFAOYSA-N 50002160 5-Chloro-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL132446 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002160&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10340978 103916466 CHEMBL132446 ZINC13728613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003653 C(CCCc1c[nH]c2ccccc12)CCN1CCC(=CC1)c1ccccc1 InChI=1S/C25H30N2/c1(4-12-23-20-26-25-14-8-7-13-24(23)25)2-9-17-27-18-15-22(16-19-27)21-10-5-3-6-11-21/h3,5-8,10-11,13-15,20,26H,1-2,4,9,12,16-19H2 IAKOYHDOZKAROP-UHFFFAOYSA-N 50002176 3-[6-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-hexyl]-1H-indole::CHEMBL130614 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002176&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977979 103916482 CHEMBL130614 ZINC13728580 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003654 C(CCc1c[nH]c2ccccc12)CN1CCC(=CC1)c1ccccc1 InChI=1S/C23H26N2/c1-2-8-19(9-3-1)20-13-16-25(17-14-20)15-7-6-10-21-18-24-23-12-5-4-11-22(21)23/h1-5,8-9,11-13,18,24H,6-7,10,14-17H2 AACJICLCLVMZKK-UHFFFAOYSA-N 50002172 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL44231 D(2) dopamine receptor Rattus norvegicus 6.4 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002172&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6917760 103916478 CHEMBL44231 ZINC02541533 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003658 COc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C24H28N2O/c1-27-22-11-9-19(10-12-22)20-13-16-26(17-14-20)15-5-4-6-21-18-25-24-8-3-2-7-23(21)24/h2-3,7-13,18,25H,4-6,14-17H2,1H3 KKBZGGCJLOKSKV-UHFFFAOYSA-N 50002168 3-{4-[4-(4-Methoxy-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL339954 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002168&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10092189 103916474 CHEMBL339954 ZINC13728595 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003659 C(CCc1c[nH]c2ccccc12)CN1CCC(CC1)c1ccccc1 InChI=1S/C23H28N2/c1-2-8-19(9-3-1)20-13-16-25(17-14-20)15-7-6-10-21-18-24-23-12-5-4-11-22(21)23/h1-5,8-9,11-12,18,20,24H,6-7,10,13-17H2 JHLJHQQFPBTTJE-UHFFFAOYSA-N 50002164 3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole::CHEMBL59335 D(2) dopamine receptor Rattus norvegicus >100 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002164&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10451707 103916470 CHEMBL59335 ZINC13728601 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003660 Clc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H25ClN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-12,17,25H,3-5,13-16H2 VDPNPEDMQPLESI-UHFFFAOYSA-N 50002166 3-{4-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL130501 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002166&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10386308 103916472 CHEMBL130501 ZINC13728589 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003662 Cn1cc(CCCCN2CCC(=CC2)c2ccccc2)c2ccccc12 InChI=1S/C24H28N2/c1-25-19-22(23-12-5-6-13-24(23)25)11-7-8-16-26-17-14-21(15-18-26)20-9-3-2-4-10-20/h2-6,9-10,12-14,19H,7-8,11,15-18H2,1H3 XJWCIRDJJRTWNX-UHFFFAOYSA-N 50002159 1-Methyl-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL131356 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002159&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10474937 103916465 CHEMBL131356 ZINC13728604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003664 Fc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C23H25FN2/c24-21-9-10-23-22(16-21)20(17-25-23)8-4-5-13-26-14-11-19(12-15-26)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,25H,4-5,8,12-15H2 CHPQXURJLAVZHE-UHFFFAOYSA-N 50002158 5-Fluoro-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL338710 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10475149 103916464 CHEMBL338710 ZINC13728610 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003666 COc1ccc2c(CCCCN3CCC(=CC3)c3ccccc3)c[nH]c2c1 InChI=1S/C24H28N2O/c1-27-22-10-11-23-21(18-25-24(23)17-22)9-5-6-14-26-15-12-20(13-16-26)19-7-3-2-4-8-19/h2-4,7-8,10-12,17-18,25H,5-6,9,13-16H2,1H3 PUZDYVQNYUCMKE-UHFFFAOYSA-N 50002175 6-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL130659 D(2) dopamine receptor Rattus norvegicus 9 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002175&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10475895 103916481 CHEMBL130659 ZINC13728616 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003669 C(Cc1c[nH]c2ccccc12)N1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c1-2-6-17(7-3-1)18-10-13-23(14-11-18)15-12-19-16-22-21-9-5-4-8-20(19)21/h1-10,16,22H,11-15H2 ANEFQMOYWNJZFI-UHFFFAOYSA-N 50002163 3-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-ethyl]-1H-indole::CHEMBL127609 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002163&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086288 103916469 CHEMBL127609 ZINC13728571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992734 CN1CCN(CC1)C1=Nc2ccccc2Sc2ncccc12 InChI=1S/C17H18N4S/c1-20-9-11-21(12-10-20)16-13-5-4-8-18-17(13)22-15-7-3-2-6-14(15)19-16/h2-8H,9-12H2,1H3 VJNQLNPFELPXCU-UHFFFAOYSA-N 50407279 CHEMBL356076 D(2) dopamine receptor Rattus norvegicus 4074 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407279&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10335576 163356303 CHEMBL356076 ZINC13734593 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992735 CN1CCN(CC1)C1=Nc2cc(C)ccc2Oc2ncccc12 InChI=1S/C18H20N4O/c1-13-5-6-16-15(12-13)20-17(22-10-8-21(2)9-11-22)14-4-3-7-19-18(14)23-16/h3-7,12H,8-11H2,1-2H3 NDRLZNWSSNZRJD-UHFFFAOYSA-N 50407280 CHEMBL151809 D(2) dopamine receptor Rattus norvegicus 1230 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10040938 163356304 CHEMBL151809 ZINC13734590 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992739 CN1CCN(CC1)C1=Nc2cc(F)ccc2Cc2ccccc12 InChI=1S/C19H20FN3/c1-22-8-10-23(11-9-22)19-17-5-3-2-4-14(17)12-15-6-7-16(20)13-18(15)21-19/h2-7,13H,8-12H2,1H3 OBWGMKKHCLHVIE-UHFFFAOYSA-N 50040241 3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine(fluperlapine)::CHEMBL63756::Fluperlapine D(2) dopamine receptor Rattus norvegicus 132 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040241&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 49381 103972301 CHEMBL63756 279 C10967 ZINC26247473 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992740 CN1CCN(CC1)C1=Nc2cccnc2Sc2ccc(Cl)cc12 InChI=1S/C17H17ClN4S/c1-21-7-9-22(10-8-21)16-13-11-12(18)4-5-15(13)23-17-14(20-16)3-2-6-19-17/h2-6,11H,7-10H2,1H3 VICVODAUYHWJHA-UHFFFAOYSA-N 50407282 CHEMBL433744 D(2) dopamine receptor Rattus norvegicus 263 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407282&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10360174 163356306 CHEMBL433744 ZINC13734583 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992742 CN1CCN(CC1)C1=Nc2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C18H18ClN3S/c1-21-8-10-22(11-9-21)18-14-12-13(19)6-7-16(14)23-17-5-3-2-4-15(17)20-18/h2-7,12H,8-11H2,1H3 KAAZGXDPUNNEFN-UHFFFAOYSA-N 50040237 2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(clothiapine)::2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL304902::Clothiapine D(2) dopamine receptor Rattus norvegicus 4.5 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040237&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16351 103972297 CHEMBL304902 ZINC26185346 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992745 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Sc2ccccc12 InChI=1S/C18H18ClN3S/c1-21-8-10-22(11-9-21)18-14-4-2-3-5-16(14)23-17-7-6-13(19)12-15(17)20-18/h2-7,12H,8-11H2,1H3 KPQVFXHERXUYEX-UHFFFAOYSA-N 50040243 8-Chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine(isoclothiapine)::8-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thiazepine::8-chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine::CHEMBL67284 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040243 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040243&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9928073 103972303 CHEMBL67284 ZINC13734596 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992747 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Oc2ncccc12 InChI=1S/C17H17ClN4O/c1-21-7-9-22(10-8-21)16-13-3-2-6-19-17(13)23-15-5-4-12(18)11-14(15)20-16/h2-6,11H,7-10H2,1H3 XUSZOVSAUPFWTP-UHFFFAOYSA-N 50382674 CHEMBL147463::CHEMBL2022280 D(2) dopamine receptor Rattus norvegicus 1202 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50382674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50382674&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 188249 160861757 CHEMBL2022280CHEMBL147463 ZINC27560709 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992748 CN1CCN(CC1)C1=Nc2cccnc2Sc2ccccc12 InChI=1S/C17H18N4S/c1-20-9-11-21(12-10-20)16-13-5-2-3-7-15(13)22-17-14(19-16)6-4-8-18-17/h2-8H,9-12H2,1H3 QWVMUCNKNQTBRW-UHFFFAOYSA-N 50407285 CHEMBL435441 D(2) dopamine receptor Rattus norvegicus 6607 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407285&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9972693 163356309 CHEMBL435441 ZINC13734580 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992751 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992752 CN1CCN(CC1)C1=Nc2cccnc2Oc2ccccc12 InChI=1S/C17H18N4O/c1-20-9-11-21(12-10-20)16-13-5-2-3-7-15(13)22-17-14(19-16)6-4-8-18-17/h2-8H,9-12H2,1H3 LSUUDGRQSAQSCO-UHFFFAOYSA-N 50407286 CHEMBL149108 D(2) dopamine receptor Rattus norvegicus 10965 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407286 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407286&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10402195 163356310 CHEMBL149108 ZINC13734577 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992753 CN1CCN(CC1)C1=Nc2cccnc2Oc2ccc(Cl)cc12 InChI=1S/C17H17ClN4O/c1-21-7-9-22(10-8-21)16-13-11-12(18)4-5-15(13)23-17-14(20-16)3-2-6-19-17/h2-6,11H,7-10H2,1H3 CMKNDZODKSREHV-UHFFFAOYSA-N 50407281 CHEMBL149240 D(2) dopamine receptor Rattus norvegicus 363 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11724078 163356305 CHEMBL149240 ZINC27560897 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992755 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.87 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992756 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 2 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992759 CN1CCN(CC1)C1=Nc2ccccc2Oc2ncccc12 InChI=1S/C17H18N4O/c1-20-9-11-21(12-10-20)16-13-5-4-8-18-17(13)22-15-7-3-2-6-14(15)19-16/h2-8H,9-12H2,1H3 XFCSELOAQOHEHG-UHFFFAOYSA-N 50407287 CHEMBL146741 D(2) dopamine receptor Rattus norvegicus 14791 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407287&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10108504 163356311 CHEMBL146741 ZINC13734587 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992762 CN1CCN(CC1)C1=Nc2ccccc2Nc2ccc(Cl)cc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-12-13(19)6-7-15(14)20-16-4-2-3-5-17(16)21-18/h2-7,12,20H,8-11H2,1H3 APOMSSAGEAOUGO-UHFFFAOYSA-N 50010594 2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::2-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(isoclozapine)::CHEMBL415300::ISOCLOZAPINE D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010594 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010594&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16104 103923369 CHEMBL415300 ZINC25973757 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50992763 CN1CCN(CC1)C1=Nc2cnccc2Sc2ccccc12 InChI=1S/C17H18N4S/c1-20-8-10-21(11-9-20)17-13-4-2-3-5-15(13)22-16-6-7-18-12-14(16)19-17/h2-7,12H,8-11H2,1H3 GCTKZGZNZBTSIN-UHFFFAOYSA-N 50407283 CHEMBL151263 D(2) dopamine receptor Rattus norvegicus 2291 ChEMBL 10.1021/jm00030a011 10.7270/Q2HX1DWK 7907148 Liegeois, JF; Rogister, FA; Bruhwyler, J; Damas, J; Nguyen, TP; Inarejos, MO; Chleide, EM; Mercier, MG; Delarge, JE University of Li£ge http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50407283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50407283&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 131990 163356307 CHEMBL151263 ZINC27617674 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50985756 CN(C)C[C@@H]1C[C@H]2N(O1)c1ccccc1Cc1ccccc21 InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1 BTSCZNWXJQSJIE-QFBILLFUSA-N 50146360 CHEMBL328573::Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-yl)methyl]-amine D(2) dopamine receptor Rattus norvegicus 195 ChEMBL 10.1016/s0960-894x(01)00721-1 10.7270/Q23J3F4C 11755364 Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146360&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9839081 104034979 CHEMBL328573 ZINC13436820 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50985784 CN(C)C[C@@H]1C[C@H]2N(O1)c1ccccc1Cc1ccccc21 InChI=1S/C19H22N2O/c1-20(2)13-16-12-19-17-9-5-3-7-14(17)11-15-8-4-6-10-18(15)21(19)22-16/h3-10,16,19H,11-13H2,1-2H3/t16-,19+/m0/s1 BTSCZNWXJQSJIE-QFBILLFUSA-N 50146360 CHEMBL328573::Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-yl)methyl]-amine D(2) dopamine receptor Rattus norvegicus 195 ChEMBL 10.1016/S0960-894X(01)00722-3 10.7270/Q2ZW1N3V 11755365 Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146360 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146360&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9839081 104034979 CHEMBL328573 ZINC13436820 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50989057 OC1CCC2CCc3c(ccc[n+]3Cc3ccccc3)C2C1 InChI=1S/C20H24NO/c22-17-10-8-16-9-11-20-18(19(16)13-17)7-4-12-21(20)14-15-5-2-1-3-6-15/h1-7,12,16-17,19,22H,8-11,13-14H2/q+1 ZSVZYAJCRPSCLW-UHFFFAOYSA-N 50405506 CHEMBL69826 D(2) dopamine receptor Rattus norvegicus 288403150 ChEMBL 10.1021/jm00395a003 10.7270/Q2FF3TJC 2824774 Van de Waterbeemd, H; el Tayar, N; Testa, B; Wikstrom, H; Largent, B University of Lausanne http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405506&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44309240 163354530 CHEMBL69826 ZINC40442232 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50985836 Cl.CN1CCN2C(C1)c1ccccc1Cc1ccccc21 InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H YNPFMWCWRVTGKJ-UHFFFAOYSA-N 31005 2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine::MIANSERIN HYDROCHLORIDE::MLS000069681::SMR000058472::cid_68551 D(2) dopamine receptor Rattus norvegicus 3548 ChEMBL 10.1016/S0960-894X(01)00722-3 10.7270/Q2ZW1N3V 11755365 Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31005&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68551 242052839 ZINC00000504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50985844 CN(C)CC1CC2N(O1)c1cc(C)ccc1Cc1ccccc21 InChI=1S/C20H24N2O/c1-14-8-9-16-11-15-6-4-5-7-18(15)20-12-17(13-21(2)3)23-22(20)19(16)10-14/h4-10,17,20H,11-13H2,1-3H3 IEMJYQZKJFERDW-UHFFFAOYSA-N 50403978 CHEMBL85735 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1016/S0960-894X(01)00722-3 10.7270/Q2ZW1N3V 11755365 Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403978&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44318842 163353002 CHEMBL85735 ZINC13437098 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50985866 CN(C)CC1CC2N(O1)c1cc(Cl)ccc1Cc1ccccc21 InChI=1S/C19H21ClN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 JTLCTTWVUAIQHD-UHFFFAOYSA-N 50403975 CHEMBL315772 D(2) dopamine receptor Rattus norvegicus 8.9 ChEMBL 10.1016/S0960-894X(01)00722-3 10.7270/Q2ZW1N3V 11755365 Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403975&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10381889 163352999 CHEMBL315772 ZINC13437085 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50985869 CN(C)CC1CC2N(O1)c1cc(F)ccc1Cc1ccccc21 InChI=1S/C19H21FN2O/c1-21(2)12-16-11-19-17-6-4-3-5-13(17)9-14-7-8-15(20)10-18(14)22(19)23-16/h3-8,10,16,19H,9,11-12H2,1-2H3 MSQRTETUBFIHMP-UHFFFAOYSA-N 50403974 CHEMBL84931 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1016/S0960-894X(01)00722-3 10.7270/Q2ZW1N3V 11755365 Andres, JI; Alcazar, J; Alonso, JM; Diaz, A; Fernandez, J; Gil, P; Iturrino, L; Matesanz, E; Meert, TF; Megens, A; Sipido, VK Janssen-Cilag S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403974&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44318454 163352998 CHEMBL84931 ZINC13437207 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50634695 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(OC)c1OC InChI=1S/C18H28N2O4/c1-5-12-10-14(23-3)17(24-4)15(16(12)21)18(22)19-11-13-8-7-9-20(13)6-2/h10,13,21H,5-9,11H2,1-4H3,(H,19,22)/t13-/m0/s1 NHGHSSSIIOPHJZ-ZDUSSCGKSA-N 50368067 CHEMBL1907702 D(2) dopamine receptor Rattus norvegicus 0.770000 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368067&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668300 160847169 CHEMBL1907702 ZINC34343070 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50634696 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(OC)c1OC InChI=1S/C16H23ClN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 DVNOGBDQNYJXJS-JTQLQIEISA-N 50368065 CHEMBL1907692 D(2) dopamine receptor Rattus norvegicus 1.7 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668289 160847167 CHEMBL1907692 ZINC34343065 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50634697 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50634698 CCCc1cc(OC)c(OC)c(C(=O)NC[C@@H]2CCCN2CC)c1O InChI=1S/C19H30N2O4/c1-5-8-13-11-15(24-3)18(25-4)16(17(13)22)19(23)20-12-14-9-7-10-21(14)6-2/h11,14,22H,5-10,12H2,1-4H3,(H,20,23)/t14-/m0/s1 XGLIHZCJAFMECG-AWEZNQCLSA-N 50368060 CHEMBL1907695 D(2) dopamine receptor Rattus norvegicus 2.4 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368060&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668308 160847162 CHEMBL1907695 ZINC13821895 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50634699 CCN1CCC[C@@H]1CNC(=O)c1c(O)c(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m1/s1 WGLPSCZHULDZSS-SNVBAGLBSA-N 50368062 CHEMBL1907915 D(2) dopamine receptor Rattus norvegicus 79 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368062&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14668294 160847164 CHEMBL1907915 ZINC00575720 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50634700 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 6.9 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50634701 CCN1CCC[C@H]1CNC(=O)c1c(O)ccc(OC)c1OC InChI=1S/C16H24N2O4/c1-4-18-9-5-6-11(18)10-17-16(20)14-12(19)7-8-13(21-2)15(14)22-3/h7-8,11,19H,4-6,9-10H2,1-3H3,(H,17,20)/t11-/m0/s1 DQDAHRKHWVTGOB-NSHDSACASA-N 50010724 CHEMBL305916::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 8.8 ChEMBL 10.1021/jm00166a012 10.7270/Q24X58DR 1969484 Hogberg, T; Bengtsson, S; de Paulis, T; Johansson, L; Strom, P; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14416355 103923470 CHEMBL305916 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51052516 Oc1ccc(cc1)N1CCN(Cc2cnn(c2)-c2ccc(Cl)cc2)CC1 InChI=1S/C20H21ClN4O/c21-17-1-3-19(4-2-17)25-15-16(13-22-25)14-23-9-11-24(12-10-23)18-5-7-20(26)8-6-18/h1-8,13,15,26H,9-12,14H2 HBGSAORKQHKGPY-UHFFFAOYSA-N 50429260 CHEMBL2333732 D(2) dopamine receptor Rattus norvegicus 530 ChEMBL 10.1016/j.ejmech.2012.08.011 10.7270/Q2QZ2CBK 23353740 Gomes, TF; Pompeu, TE; Rodrigues, DA; Noel, F; Menegatti, R; Andrade, CH; Sabino, JR; Gil, ES; Dalla Costa, T; Betti, AH; Antonio, CB; Rates, SM; Fraga, CA; Barreiro, EJ; de Oliveira, V Universidade Federal de Goi£s http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50429260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50429260&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71652196 164158135 CHEMBL2333732 ZINC95592057 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51052523 Clc1ccc(cc1)-n1cc(CN2CCN(CC2)c2ccccc2)cn1 InChI=1S/C20H21ClN4/c21-18-6-8-20(9-7-18)25-16-17(14-22-25)15-23-10-12-24(13-11-23)19-4-2-1-3-5-19/h1-9,14,16H,10-13,15H2 MHJWMIITIMUUKU-UHFFFAOYSA-N 50308002 1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-phenylpiperazine::CHEMBL597601 D(2) dopamine receptor Rattus norvegicus 380 ChEMBL 10.1016/j.ejmech.2012.08.011 10.7270/Q2QZ2CBK 23353740 Gomes, TF; Pompeu, TE; Rodrigues, DA; Noel, F; Menegatti, R; Andrade, CH; Sabino, JR; Gil, ES; Dalla Costa, T; Betti, AH; Antonio, CB; Rates, SM; Fraga, CA; Barreiro, EJ; de Oliveira, V Universidade Federal de Goi£s http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50308002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50308002&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11624518 104162363 CHEMBL597601 ZINC53184753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51052530 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 130 ChEMBL 10.1016/j.ejmech.2012.08.011 10.7270/Q2QZ2CBK 23353740 Gomes, TF; Pompeu, TE; Rodrigues, DA; Noel, F; Menegatti, R; Andrade, CH; Sabino, JR; Gil, ES; Dalla Costa, T; Betti, AH; Antonio, CB; Rates, SM; Fraga, CA; Barreiro, EJ; de Oliveira, V Universidade Federal de Goi£s http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000589 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccc2OCCOc2c1 InChI=1S/C23H23NO2/c1-2-7-20(8-3-1)21-11-14-24(15-12-21)13-5-4-6-19-9-10-22-23(18-19)26-17-16-25-22/h1-3,7-11,18H,5,12-17H2 CRULMHGTCPWBCB-UHFFFAOYSA-N 50052526 1-[4-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-but-3-ynyl]-4-phenyl-1,2,3,6-tetrahydro-pyridine::CHEMBL108375 D(2) dopamine receptor Rattus norvegicus 125.89 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052526&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10831379 103949378 CHEMBL108375 ZINC13757302 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000601 Oc1ccc(cc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H21NO/c23-21-11-9-18(10-12-21)6-4-5-15-22-16-13-20(14-17-22)19-7-2-1-3-8-19/h1-3,7-13,23H,5,14-17H2 JLZXBPBMBUIBQC-UHFFFAOYSA-N 50052542 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenol::CHEMBL109171 D(2) dopamine receptor Rattus norvegicus 53.7 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052542&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10614402 103949394 CHEMBL109171 ZINC13757292 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000612 Nc1ccc(cc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c22-21-11-9-18(10-12-21)6-4-5-15-23-16-13-20(14-17-23)19-7-2-1-3-8-19/h1-3,7-13H,5,14-17,22H2 STFIELBPKGAKNX-UHFFFAOYSA-N 50052531 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL108531 D(2) dopamine receptor Rattus norvegicus 47.86 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10425024 103949383 CHEMBL108531 ZINC01533849 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000623 Nc1ccc(nc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C20H21N3/c21-19-9-10-20(22-16-19)8-4-5-13-23-14-11-18(12-15-23)17-6-2-1-3-7-17/h1-3,6-7,9-11,16H,5,12-15,21H2 LPLZFZAIOWVRTJ-UHFFFAOYSA-N 50052532 6-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridin-3-ylamine::CHEMBL109101 D(2) dopamine receptor Rattus norvegicus 63.1 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10086348 103949384 CHEMBL109101 ZINC01533848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000625 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccncc1 InChI=1S/C20H20N2/c1-2-7-19(8-3-1)20-11-16-22(17-12-20)15-5-4-6-18-9-13-21-14-10-18/h1-3,7-11,13-14H,5,12,15-17H2 VPUYNZMAEQVXFX-UHFFFAOYSA-N 50052533 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL110489 D(2) dopamine receptor Rattus norvegicus 32.36 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052533&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10684789 103949385 CHEMBL110489 ZINC01533847 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000630 Nc1cccc(c1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c22-21-11-6-8-18(17-21)7-4-5-14-23-15-12-20(13-16-23)19-9-2-1-3-10-19/h1-3,6,8-12,17H,5,13-16,22H2 KHTVRVDYYAMNRK-UHFFFAOYSA-N 50052535 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL108532 D(2) dopamine receptor Rattus norvegicus 87.1 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052535&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10780717 103949387 CHEMBL108532 ZINC13757298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000636 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccccn1 InChI=1S/C20H20N2/c1-2-8-18(9-3-1)19-12-16-22(17-13-19)15-7-5-11-20-10-4-6-14-21-20/h1-4,6,8-10,12,14H,7,13,15-17H2 ODQASWLALUMZKF-UHFFFAOYSA-N 50052545 2-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL110488 D(2) dopamine receptor Rattus norvegicus 134.9 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052545&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10565311 103949397 CHEMBL110488 ZINC13757294 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000648 C(CN1CCC(=CC1)c1ccccc1)C#Cc1cccnc1 InChI=1S/C20H20N2/c1-2-9-19(10-3-1)20-11-15-22(16-12-20)14-5-4-7-18-8-6-13-21-17-18/h1-3,6,8-11,13,17H,5,12,14-16H2 QNTNWSQRMBFBSH-UHFFFAOYSA-N 50052528 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridine::CHEMBL108463 D(2) dopamine receptor Rattus norvegicus 37.15 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10827222 103949380 CHEMBL108463 ZINC01533844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000665 C(CN1CCC(=CC1)c1ccccc1)C#Cc1cnc2ccccc2c1 InChI=1S/C24H22N2/c1-2-9-21(10-3-1)22-13-16-26(17-14-22)15-7-6-8-20-18-23-11-4-5-12-24(23)25-19-20/h1-5,9-13,18-19H,7,14-17H2 VNMWEXMNOPGWQX-UHFFFAOYSA-N 50052536 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-quinoline::CHEMBL108790 D(2) dopamine receptor Rattus norvegicus 30.2 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052536&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9905884 103949388 CHEMBL108790 ZINC13757286 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000687 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccc2occc2c1 InChI=1S/C23H21NO/c1-2-7-20(8-3-1)21-11-15-24(16-12-21)14-5-4-6-19-9-10-23-22(18-19)13-17-25-23/h1-3,7-11,13,17-18H,5,12,14-16H2 SAPVVBMVHBHWPK-UHFFFAOYSA-N 50052548 1-(4-Benzofuran-5-yl-but-3-ynyl)-4-phenyl-1,2,3,6-tetrahydro-pyridine::CHEMBL419021 D(2) dopamine receptor Rattus norvegicus 436.52 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052548&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10782455 103949400 CHEMBL419021 ZINC13757304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000692 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccccc1 InChI=1S/C21H21N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-14H,8,15-18H2 LVLZJQZUFDAJLN-UHFFFAOYSA-N 50052534 4-Phenyl-1-(4-phenyl-but-3-ynyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL110324 D(2) dopamine receptor Rattus norvegicus 281.84 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10827160 103949386 CHEMBL110324 ZINC13757290 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000702 C(CN1CCC(=CC1)c1ccccc1)C#Cc1cncc2ccccc12 InChI=1S/C24H22N2/c1-2-8-20(9-3-1)21-13-16-26(17-14-21)15-7-6-11-23-19-25-18-22-10-4-5-12-24(22)23/h1-5,8-10,12-13,18-19H,7,14-17H2 CPBVYXALZPNTBE-UHFFFAOYSA-N 50052539 4-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-isoquinoline::CHEMBL324445 D(2) dopamine receptor Rattus norvegicus 72.44 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052539&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10830863 103949391 CHEMBL324445 ZINC13757296 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000706 C(CN1CCC(=CC1)c1ccccc1)C#Cc1ccc2[nH]ccc2c1 InChI=1S/C23H22N2/c1-2-7-20(8-3-1)21-12-16-25(17-13-21)15-5-4-6-19-9-10-23-22(18-19)11-14-24-23/h1-3,7-12,14,18,24H,5,13,15-17H2 OAJVHYXJWDAZTN-UHFFFAOYSA-N 50052537 5-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-1H-indole::CHEMBL109199 D(2) dopamine receptor Rattus norvegicus 194.98 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052537&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10711254 103949389 CHEMBL109199 ZINC13757293 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000713 COc1ccc(cc1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C22H23NO/c1-24-22-12-10-19(11-13-22)7-5-6-16-23-17-14-21(15-18-23)20-8-3-2-4-9-20/h2-4,8-14H,6,15-18H2,1H3 DRTKYNKXTWRNKR-UHFFFAOYSA-N 50052547 1-[4-(4-Methoxy-phenyl)-but-3-ynyl]-4-phenyl-1,2,3,6-tetrahydro-pyridine::CHEMBL108530 D(2) dopamine receptor Rattus norvegicus 323.59 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052547&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10543539 103949399 CHEMBL108530 ZINC13757301 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000717 Nc1ccc(cn1)C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C20H21N3/c21-20-10-9-17(16-22-20)6-4-5-13-23-14-11-19(12-15-23)18-7-2-1-3-8-18/h1-3,7-11,16H,5,12-15H2,(H2,21,22) KAPNJGZVRYPTJW-UHFFFAOYSA-N 50052530 5-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-pyridin-2-ylamine::CHEMBL109063 D(2) dopamine receptor Rattus norvegicus 33.11 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357631 103949382 CHEMBL109063 ZINC26941584 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51000718 Nc1ccccc1C#CCCN1CCC(=CC1)c1ccccc1 InChI=1S/C21H22N2/c22-21-12-5-4-10-20(21)11-6-7-15-23-16-13-19(14-17-23)18-8-2-1-3-9-18/h1-5,8-10,12-13H,7,14-17,22H2 ANMMAXZZUOHCED-UHFFFAOYSA-N 50052543 2-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-but-1-ynyl]-phenylamine::CHEMBL321858 D(2) dopamine receptor Rattus norvegicus 181.97 ChEMBL 10.1016/j.bmcl.2005.02.012 10.7270/Q2RR20G2 15808487 Hansch, C; Verma, RP; Kurup, A; Mekapati, SB Pomona College http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50052543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50052543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10828224 103949395 CHEMBL321858 ZINC13757299 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031358 O=C1CC2(CCCC2)CC(=O)N1CCCCNCC1COc2ccc3ccccc3c2O1 InChI=1S/C26H32N2O4/c29-23-15-26(11-3-4-12-26)16-24(30)28(23)14-6-5-13-27-17-20-18-31-22-10-9-19-7-1-2-8-21(19)25(22)32-20/h1-2,7-10,20,27H,3-6,11-18H2 VFKQPDBDZNBCKD-UHFFFAOYSA-N 50421834 CHEMBL12311 D(2) dopamine receptor Rattus norvegicus 158 ChEMBL 10.1021/jm00401a007 10.7270/Q20Z74K6 3373482 Hibert, MF; Gittos, MW; Middlemiss, DN; Mir, AK; Fozard, JR Merrell Dow Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421834&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13673326 164150709 CHEMBL12311 ZINC26028482 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031364 O=C1CC2(CCCC2)CC(=O)N1CCCCNCC1COc2c(O1)ccc1ccccc21 InChI=1S/C26H32N2O4/c29-23-15-26(11-3-4-12-26)16-24(30)28(23)14-6-5-13-27-17-20-18-31-25-21-8-2-1-7-19(21)9-10-22(25)32-20/h1-2,7-10,20,27H,3-6,11-18H2 CPZXZWSBPRKTEA-UHFFFAOYSA-N 50421838 CHEMBL11787 D(2) dopamine receptor Rattus norvegicus 316 ChEMBL 10.1021/jm00401a007 10.7270/Q20Z74K6 3373482 Hibert, MF; Gittos, MW; Middlemiss, DN; Mir, AK; Fozard, JR Merrell Dow Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421838&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44267852 164150713 CHEMBL11787 ZINC26025309 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031367 O=C1CC2(CCCC2)CC(=O)N1CCCCNC[C@@H]1COc2ccccc2O1 InChI=1S/C22H30N2O4/c25-20-13-22(9-3-4-10-22)14-21(26)24(20)12-6-5-11-23-15-17-16-27-18-7-1-2-8-19(18)28-17/h1-2,7-8,17,23H,3-6,9-16H2/t17-/m1/s1 HCVRCHQFYYZPHT-QGZVFWFLSA-N 50421835 CHEMBL12124 D(2) dopamine receptor Rattus norvegicus 158 ChEMBL 10.1021/jm00401a007 10.7270/Q20Z74K6 3373482 Hibert, MF; Gittos, MW; Middlemiss, DN; Mir, AK; Fozard, JR Merrell Dow Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23786480 164150710 CHEMBL12124 ZINC03995603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031369 O=C1CC2(CCCC2)CC(=O)N1CCCCNC[C@H]1COc2ccccc2O1 InChI=1S/C22H30N2O4/c25-20-13-22(9-3-4-10-22)14-21(26)24(20)12-6-5-11-23-15-17-16-27-18-7-1-2-8-19(18)28-17/h1-2,7-8,17,23H,3-6,9-16H2/t17-/m0/s1 HCVRCHQFYYZPHT-KRWDZBQOSA-N 50421836 CHEMBL12129 D(2) dopamine receptor Rattus norvegicus 79 ChEMBL 10.1021/jm00401a007 10.7270/Q20Z74K6 3373482 Hibert, MF; Gittos, MW; Middlemiss, DN; Mir, AK; Fozard, JR Merrell Dow Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421836&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604720 164150711 CHEMBL12129 ZINC02557963 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031587 [O-][N+](=O)c1ccc(CCN2CC[C@@H]3[C@@H](CCc4ccccc34)C2)cc1 InChI=1S/C21H24N2O2/c24-23(25)19-9-5-16(6-10-19)11-13-22-14-12-21-18(15-22)8-7-17-3-1-2-4-20(17)21/h1-6,9-10,18,21H,7-8,11-15H2/t18-,21+/m0/s1 VMDLVEVOBUKRBG-GHTZIAJQSA-N 50421912 CHEMBL545447 D(2) dopamine receptor Rattus norvegicus 589 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421912&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44304443 164150787 CHEMBL545447 ZINC26173787 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031598 CCCCN1CCC2=C(Cc3ccccc23)C1 InChI=1S/C16H21N/c1-2-3-9-17-10-8-16-14(12-17)11-13-6-4-5-7-15(13)16/h4-7H,2-3,8-12H2,1H3 ZTAAYZUUCPOIBW-UHFFFAOYSA-N 50421899 CHEMBL545688 D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421899&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15751790 164150774 CHEMBL545688 ZINC13455461 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031600 C(Cc1ccccc1)N1CC[C@@H]2[C@@H](CCc3ccccc23)C1 InChI=1S/C21H25N/c1-2-6-17(7-3-1)12-14-22-15-13-21-19(16-22)11-10-18-8-4-5-9-20(18)21/h1-9,19,21H,10-16H2/t19-,21+/m0/s1 DXALZRXMUCRVSF-PZJWPPBQSA-N 50421907 CHEMBL540274 D(2) dopamine receptor Rattus norvegicus 162 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44304447 164150782 CHEMBL540274 ZINC01492988 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031603 CCCCN1CCC2=C(CCc3ccccc23)C1 InChI=1S/C17H23N/c1-2-3-11-18-12-10-17-15(13-18)9-8-14-6-4-5-7-16(14)17/h4-7H,2-3,8-13H2,1H3 VXQVYBORCSUFDN-UHFFFAOYSA-N 50155606 3-Butyl-1,2,3,4,5,6-hexahydro-benzo[f]isoquinoline::CHEMBL188713::CHEMBL541299 D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155606&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15751760 104043019 CHEMBL188713CHEMBL541299 ZINC13455418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031604 CCCCN1CC[C@@H]2[C@@H](CCc3ccccc23)C1 InChI=1S/C17H25N/c1-2-3-11-18-12-10-17-15(13-18)9-8-14-6-4-5-7-16(14)17/h4-7,15,17H,2-3,8-13H2,1H3/t15-,17+/m0/s1 HHEIQDXGHHAKRI-DOTOQJQBSA-N 50421922 CHEMBL544282 D(2) dopamine receptor Rattus norvegicus 145 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421922&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15751763 164150797 CHEMBL544282 ZINC13455427 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031606 COc1ccc(CN2CC[C@@H]3[C@@H](CCc4ccccc34)C2)cc1 InChI=1S/C21H25NO/c1-23-19-10-6-16(7-11-19)14-22-13-12-21-18(15-22)9-8-17-4-2-3-5-20(17)21/h2-7,10-11,18,21H,8-9,12-15H2,1H3/t18-,21+/m0/s1 MDACNEPDEQTBEM-GHTZIAJQSA-N 50421926 CHEMBL541052 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421926&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44304411 164150801 CHEMBL541052 ZINC26151778 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031607 CCCCN1CC[C@H]2[C@@H](CCc3ccccc23)C1 InChI=1S/C17H25N/c1-2-3-11-18-12-10-17-15(13-18)9-8-14-6-4-5-7-16(14)17/h4-7,15,17H,2-3,8-13H2,1H3/t15-,17-/m0/s1 HHEIQDXGHHAKRI-RDJZCZTQSA-N 50421917 CHEMBL2093874 D(2) dopamine receptor Rattus norvegicus 389 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15751764 164150792 CHEMBL2093874 ZINC02010245 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031608 CC(C)(C)c1ccc(CN2CC[C@@H]3[C@@H](CCc4ccccc34)C2)cc1 InChI=1S/C24H31N/c1-24(2,3)21-12-8-18(9-13-21)16-25-15-14-23-20(17-25)11-10-19-6-4-5-7-22(19)23/h4-9,12-13,20,23H,10-11,14-17H2,1-3H3/t20-,23+/m0/s1 DXWOYQQCOACBBA-NZQKXSOJSA-N 50421924 CHEMBL544280 D(2) dopamine receptor Rattus norvegicus 288 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44304409 164150799 CHEMBL544280 ZINC26147669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031611 CCCCN1CCC2C(C1)CCCc1ccccc21 InChI=1S/C18H27N/c1-2-3-12-19-13-11-18-16(14-19)9-6-8-15-7-4-5-10-17(15)18/h4-5,7,10,16,18H,2-3,6,8-9,11-14H2,1H3 DZLIMMKPSQDNFZ-UHFFFAOYSA-N 50421894 CHEMBL555581 D(2) dopamine receptor Rattus norvegicus 166 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421894&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15751793 164150769 CHEMBL555581 ZINC34742151 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031612 CCCCN1CCC2=C(C1)CCCc1ccccc21 InChI=1S/C18H25N/c1-2-3-12-19-13-11-18-16(14-19)9-6-8-15-7-4-5-10-17(15)18/h4-5,7,10H,2-3,6,8-9,11-14H2,1H3 WYJFAAMABHSKFH-UHFFFAOYSA-N 50421900 CHEMBL545217 D(2) dopamine receptor Rattus norvegicus 62 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421900&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15751791 164150775 CHEMBL545217 ZINC13455469 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031614 C1CCC(CC1)N1CC[C@@H]2[C@@H](CCc3ccccc23)C1 InChI=1S/C19H27N/c1-2-7-17(8-3-1)20-13-12-19-16(14-20)11-10-15-6-4-5-9-18(15)19/h4-6,9,16-17,19H,1-3,7-8,10-14H2/t16-,19+/m0/s1 FUMLYVJDBXPSSP-QFBILLFUSA-N 50421905 CHEMBL553265 D(2) dopamine receptor Rattus norvegicus 2692 ChEMBL 10.1021/jm00089a012 10.7270/Q2MP54K8 1317922 Russell, MG; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Noble, AJ Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421905&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44304251 164150780 CHEMBL553265 ZINC26171195 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031618 C(C1CCCCC1)N1CCC2(CCc3ccccc23)CC1 InChI=1S/C20H29N/c1-2-6-17(7-3-1)16-21-14-12-20(13-15-21)11-10-18-8-4-5-9-19(18)20/h4-5,8-9,17H,1-3,6-7,10-16H2 XWGDOCSDEQCYHX-UHFFFAOYSA-N 50421932 CHEMBL1743999 D(2) dopamine receptor Rattus norvegicus 6607 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421932&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163160 164150807 CHEMBL1743999 ZINC01493274 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031619 COc1ccc(CN2CCC3(CCc4ccccc34)CC2)cc1 InChI=1S/C21H25NO/c1-23-19-8-6-17(7-9-19)16-22-14-12-21(13-15-22)11-10-18-4-2-3-5-20(18)21/h2-9H,10-16H2,1H3 XURMNFGOCHGOGM-UHFFFAOYSA-N 50421933 CHEMBL1744016 D(2) dopamine receptor Rattus norvegicus 617 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421933&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163163 164150808 CHEMBL1744016 ZINC01493275 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031625 Cc1ccc(CN2CCC3(CCCc4ccccc34)CC2)cc1 InChI=1S/C22H27N/c1-18-8-10-19(11-9-18)17-23-15-13-22(14-16-23)12-4-6-20-5-2-3-7-21(20)22/h2-3,5,7-11H,4,6,12-17H2,1H3 UJQXCFMWQIJGRX-UHFFFAOYSA-N 50421939 CHEMBL1744003 D(2) dopamine receptor Rattus norvegicus 174 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163148 164150814 CHEMBL1744003 ZINC13455504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031626 CC(C)=CCN1CCC2(CCCc3ccccc23)CC1 InChI=1S/C19H27N/c1-16(2)9-13-20-14-11-19(12-15-20)10-5-7-17-6-3-4-8-18(17)19/h3-4,6,8-9H,5,7,10-15H2,1-2H3 FZKJBLCZXHAPBD-UHFFFAOYSA-N 50421940 CHEMBL62770 D(2) dopamine receptor Rattus norvegicus 5495 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421940&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163140 164150815 CHEMBL62770 ZINC13455482 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031627 CCCCCCN1CCC2(CCCc3ccccc23)CC1 InChI=1S/C20H31N/c1-2-3-4-7-15-21-16-13-20(14-17-21)12-8-10-18-9-5-6-11-19(18)20/h5-6,9,11H,2-4,7-8,10,12-17H2,1H3 PADFSWOFTRXJBA-UHFFFAOYSA-N 50421941 CHEMBL1744001 D(2) dopamine receptor Rattus norvegicus 2042 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163143 164150816 CHEMBL1744001 ZINC13455490 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031630 C(N1CCC2(CC1)CCCCc1ccccc21)c1ccccc1 InChI=1S/C22H27N/c1-2-8-19(9-3-1)18-23-16-14-22(15-17-23)13-7-6-11-20-10-4-5-12-21(20)22/h1-5,8-10,12H,6-7,11,13-18H2 XZCHMODGNZASPX-UHFFFAOYSA-N 50421944 CHEMBL1744011 D(2) dopamine receptor Rattus norvegicus 3715 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421944&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163136 164150819 CHEMBL1744011 ZINC01493280 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031638 CCCCN1CCC2(CCCc3ccccc23)CC1 InChI=1S/C18H27N/c1-2-3-13-19-14-11-18(12-15-19)10-6-8-16-7-4-5-9-17(16)18/h4-5,7,9H,2-3,6,8,10-15H2,1H3 GWZNBTHONPZRPP-UHFFFAOYSA-N 50170657 1''-butyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-piperidine]::1'-butyl-3,4-dihydro-2H-spiro[naphthalene-1,4'-piperidine]; HCl::CHEMBL1788381::CHEMBL62540 D(2) dopamine receptor Rattus norvegicus 10965 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50170657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50170657&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163141 104057037 CHEMBL1788381CHEMBL62540 ZINC13455484 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031643 CCCCN1CCC2(CC1)CCCCc1ccccc21 InChI=1S/C19H29N/c1-2-3-14-20-15-12-19(13-16-20)11-7-6-9-17-8-4-5-10-18(17)19/h4-5,8,10H,2-3,6-7,9,11-16H2,1H3 URYCGLSVFFVWHP-UHFFFAOYSA-N 50421935 CHEMBL1744010 D(2) dopamine receptor Rattus norvegicus 2512 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421935&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163138 164150810 CHEMBL1744010 ZINC01554626 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031645 CCCCCCN1CCC2(CCc3ccccc23)CC1 InChI=1S/C19H29N/c1-2-3-4-7-14-20-15-12-19(13-16-20)11-10-17-8-5-6-9-18(17)19/h5-6,8-9H,2-4,7,10-16H2,1H3 AJHIAKMQFRDJIB-UHFFFAOYSA-N 50421954 CHEMBL1744015 D(2) dopamine receptor Rattus norvegicus 5495 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421954&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163161 164150829 CHEMBL1744015 ZINC01554624 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031649 C(N1CCC2(CCCc3ccccc23)CC1)c1ccccc1 InChI=1S/C21H25N/c1-2-7-18(8-3-1)17-22-15-13-21(14-16-22)12-6-10-19-9-4-5-11-20(19)21/h1-5,7-9,11H,6,10,12-17H2 MLDCBJPLHBPJET-UHFFFAOYSA-N 50035097 1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-piperidine](L-687,384)::1''-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4''-piperidine]; HCl::1''-benzylspiro[1,2,3,4-tetrahydronaphthalene-1,4''-(hexahydropyridine)]::1'-benzylspiro[1,2,3,4-tetrahydronaphthalene-1,4'-(hexahydropyridine)](L-687,384)::CHEMBL1256916::CHEMBL303336::L-687384 D(2) dopamine receptor Rattus norvegicus 955 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035097&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 125328 103943145 CHEMBL1256916CHEMBL303336 ZINC01493052 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031650 CC(C)=CCN1CCC2(CCc3ccccc23)CC1 InChI=1S/C18H25N/c1-15(2)8-12-19-13-10-18(11-14-19)9-7-16-5-3-4-6-17(16)18/h3-6,8H,7,9-14H2,1-2H3 ULBZOYYHHRLQMV-UHFFFAOYSA-N 50421930 CHEMBL1788382 D(2) dopamine receptor Rattus norvegicus 16982 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421930&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 126260 164150805 CHEMBL1788382 ZINC01493276 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031654 C(C1CCCCC1)N1CCC2(CCCc3ccccc23)CC1 InChI=1S/C21H31N/c1-2-7-18(8-3-1)17-22-15-13-21(14-16-22)12-6-10-19-9-4-5-11-20(19)21/h4-5,9,11,18H,1-3,6-8,10,12-17H2 KGMNSTTVWXNUOK-UHFFFAOYSA-N 50421934 CHEMBL1744000 D(2) dopamine receptor Rattus norvegicus 1950 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421934&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163142 164150809 CHEMBL1744000 ZINC13455487 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031657 COc1ccc(CN2CCC3(CCCc4ccccc34)CC2)cc1 InChI=1S/C22H27NO/c1-24-20-10-8-18(9-11-20)17-23-15-13-22(14-16-23)12-4-6-19-5-2-3-7-21(19)22/h2-3,5,7-11H,4,6,12-17H2,1H3 PUCIJQFBXXTCMC-UHFFFAOYSA-N 50421951 CHEMBL1744002 D(2) dopamine receptor Rattus norvegicus 120 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421951&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163149 164150826 CHEMBL1744002 ZINC13455507 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031658 C(N1CCC2(CCc3ccccc23)CC1)c1ccccc1 InChI=1S/C20H23N/c1-2-6-17(7-3-1)16-21-14-12-20(13-15-21)11-10-18-8-4-5-9-19(18)20/h1-9H,10-16H2 GSXJSGMDWKPVBY-UHFFFAOYSA-N 50421946 CHEMBL1788383 D(2) dopamine receptor Rattus norvegicus 891 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4687238 164150821 CHEMBL1788383 ZINC01493272 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51031662 CCCCN1CCC2(CCc3ccccc23)CC1 InChI=1S/C17H25N/c1-2-3-12-18-13-10-17(11-14-18)9-8-15-6-4-5-7-16(15)17/h4-7H,2-3,8-14H2,1H3 FMVGPDJTALMVAC-UHFFFAOYSA-N 50421945 CHEMBL1744017 D(2) dopamine receptor Rattus norvegicus 3981 ChEMBL 10.1021/jm00089a013 10.7270/Q2GX4CVJ 1317923 Chambers, MS; Baker, R; Billington, DC; Knight, AK; Middlemiss, DN; Wong, EH Merck Sharp and Dohme Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15163162 164150820 CHEMBL1744017 ZINC01554623 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50030629 CCCN1CCC[C@H]2[C@@H]1CCc1c(O)cccc21 InChI=1S/C16H23NO/c1-2-10-17-11-4-6-13-12-5-3-7-16(18)14(12)8-9-15(13)17/h3,5,7,13,15,18H,2,4,6,8-11H2,1H3/t13-,15+/m1/s1 ANYSYRVXKLTFPB-HIFRSBDPSA-N 50452345 CHEMBL2114053 D(2) dopamine receptor Rattus norvegicus 160 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039962 225145658 CHEMBL2114053 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50571663 CS(=O)(=O)c1cccc(c1)C1CCNC1 InChI=1S/C11H15NO2S/c1-15(13,14)11-4-2-3-9(7-11)10-5-6-12-8-10/h2-4,7,10,12H,5-6,8H2,1H3 HGUNXXODCCBAQQ-UHFFFAOYSA-N 50214805 CHEMBL3706602 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10537195 376071474 CHEMBL3706602 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50571672 FC(F)(F)c1cccc(c1)C1CCNC1 InChI=1S/C11H12F3N/c12-11(13,14)10-3-1-2-8(6-10)9-4-5-15-7-9/h1-3,6,9,15H,4-5,7H2 DUYDZGBSZJZIOZ-UHFFFAOYSA-N 50214806 CHEMBL3706603 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1016/S0960-894X(96)00618-X 10.7270/Q200023S Sonesson, C; Wikström, H; Smith, MW; Svensson, K; Carlsson, A; Waters, N TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50214806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50214806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10822557 376071475 CHEMBL3706603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50017545 CN1C2CCCC1CC(C2)NC(=O)c1nn(C)c2ccccc12 InChI=1S/C18H24N4O/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23) MFWNKCLOYSRHCJ-UHFFFAOYSA-N 50000483 (BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide::(granisetron)1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide::1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide::1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide::1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide(BRL 43694)::1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide(Granisetron)::1-methyl-N-((1S,5R)-9-methyl-9-aza-bicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide::2-(9-Methyl-3,9-diaza-bicyclo[3.3.1]non-3-yl)-1-(1-methyl-1H-indol-3-yl)-ethanone(Granisetron)::BRL 43694::BRL-43694::CHEMBL519643::GRANISETRON::LY-278584 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/s0960-894x(01)00693-x 10.7270/Q20R9PX0 11755351 Iriepa, I; Villasante, FJ; Galvez, E; Labeaga, L; Innerarity, A; Orjales, A Universidad de Alcal£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50000483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50000483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search CWB 2YME,6NP0 3510 103915031 CHEMBL519643 DB00889 2292 ZINC12503197 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50017554 COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC1CN2C InChI=1S/C16H22ClN3O2/c1-20-8-9-3-4-10(20)5-14(9)19-16(21)11-6-12(17)13(18)7-15(11)22-2/h6-7,9-10,14H,3-5,8,18H2,1-2H3,(H,19,21) KAVKRBZLNSOOJY-UHFFFAOYSA-N 50108390 4-Amino-5-chloro-2-methoxy-N-(2-methyl-2-aza-bicyclo[2.2.2]oct-5-yl)-benzamide::CHEMBL56994 D(2) dopamine receptor Rattus norvegicus 842 ChEMBL 10.1016/s0960-894x(01)00693-x 10.7270/Q20R9PX0 11755351 Iriepa, I; Villasante, FJ; Galvez, E; Labeaga, L; Innerarity, A; Orjales, A Universidad de Alcal£ http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50108390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50108390&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44300153 104003609 CHEMBL56994 ZINC13586867 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50009995 C(COc1cccc2nc[nH]c12)NCc1ccccc1 InChI=1S/C16H17N3O/c1-2-5-13(6-3-1)11-17-9-10-20-15-8-4-7-14-16(15)19-12-18-14/h1-8,12,17H,9-11H2,(H,18,19) XQWCSGWUJUEAQM-UHFFFAOYSA-N 50081111 CHEMBL89420::[2-(1H-Benzoimidazol-4-yloxy)-ethyl]-benzyl-amine D(2) dopamine receptor Rattus norvegicus 9.8 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081111&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9881815 103981165 CHEMBL89420 ZINC26577725 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50009996 Clc1cc(OCCNCc2ccccc2)c2[nH]c(=S)[nH]c2c1 InChI=1S/C16H16ClN3OS/c17-12-8-13-15(20-16(22)19-13)14(9-12)21-7-6-18-10-11-4-2-1-3-5-11/h1-5,8-9,18H,6-7,10H2,(H2,19,20,22) HMFWWORRYDWEDS-UHFFFAOYSA-N 50081107 4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazole-2-thione::CHEMBL89037 D(2) dopamine receptor Rattus norvegicus 0.210000 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9949531 103981161 CHEMBL89037 ZINC01547101 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50009997 C(COc1cccc2[nH]ncc12)NCc1ccccc1 InChI=1S/C16H17N3O/c1-2-5-13(6-3-1)11-17-9-10-20-16-8-4-7-15-14(16)12-18-19-15/h1-8,12,17H,9-11H2,(H,18,19) WYGBVOBBNUHWLX-UHFFFAOYSA-N 50081109 Benzyl-[2-(1H-indazol-4-yloxy)-ethyl]-amine::CHEMBL87137 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081109&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9816808 103981163 CHEMBL87137 ZINC03917152 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50009998 C(COc1cccc2[nH]ccc12)NCc1ccccc1 InChI=1S/C17H18N2O/c1-2-5-14(6-3-1)13-18-11-12-20-17-8-4-7-16-15(17)9-10-19-16/h1-10,18-19H,11-13H2 ZEHDEZWEFBOGNZ-UHFFFAOYSA-N 50077576 Benzyl-[2-(1H-indol-4-yloxy)-ethyl]-amine::CHEMBL64283 D(2) dopamine receptor Rattus norvegicus 9.7 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077576&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9838216 103970345 CHEMBL64283 ZINC01903142 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50009999 S=c1[nH]c2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C16H17N3OS/c21-16-18-13-7-4-8-14(15(13)19-16)20-10-9-17-11-12-5-2-1-3-6-12/h1-8,17H,9-11H2,(H2,18,19,21) IMYFITBNCNWHTL-UHFFFAOYSA-N 50081108 4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazole-2-thione::CHEMBL327782 D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081108&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817774 103981162 CHEMBL327782 ZINC01547096 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010000 Cc1nc2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C17H19N3O/c1-13-19-15-8-5-9-16(17(15)20-13)21-11-10-18-12-14-6-3-2-4-7-14/h2-9,18H,10-12H2,1H3,(H,19,20) GGIUXVIFNJVWLE-UHFFFAOYSA-N 50081104 Benzyl-[2-(2-methyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine::CHEMBL87067 D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081104&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9925730 103981158 CHEMBL87067 ZINC26576445 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010002 Oc1cccc(OCCNCc2ccccc2)c1 InChI=1S/C15H17NO2/c17-14-7-4-8-15(11-14)18-10-9-16-12-13-5-2-1-3-6-13/h1-8,11,16-17H,9-10,12H2 VBTFJGYCISLKEQ-UHFFFAOYSA-N 50069914 3-(2-Benzylamino-ethoxy)-phenol::CHEMBL64508 D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069914&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11776546 103963876 CHEMBL64508 ZINC12355952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010004 O=C1Cc2c(N1)cccc2OCCNCc1ccccc1 InChI=1S/C17H18N2O2/c20-17-11-14-15(19-17)7-4-8-16(14)21-10-9-18-12-13-5-2-1-3-6-13/h1-8,18H,9-12H2,(H,19,20) CVWQKEFTSSJDLS-UHFFFAOYSA-N 50077578 4-(2-Benzylamino-ethoxy)-1,3-dihydro-indol-2-one::CHEMBL59752 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9903877 103970347 CHEMBL59752 ZINC01903144 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010006 FC(F)(F)c1nc2c(OCCNCc3ccccc3)cc(Cl)cc2[nH]1 InChI=1S/C17H15ClF3N3O/c18-12-8-13-15(24-16(23-13)17(19,20)21)14(9-12)25-7-6-22-10-11-4-2-1-3-5-11/h1-5,8-9,22H,6-7,10H2,(H,23,24) MMZIPJNBJQJCBM-UHFFFAOYSA-N 50081105 Benzyl-[2-(6-chloro-2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine::CHEMBL86504 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081105&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9820680 103981159 CHEMBL86504 ZINC03926703 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142159 FC(F)(F)c1nc2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C17H16F3N3O/c18-17(19,20)16-22-13-7-4-8-14(15(13)23-16)24-10-9-21-11-12-5-2-1-3-6-12/h1-8,21H,9-11H2,(H,22,23) BKHJHBMOHZNYEP-UHFFFAOYSA-N 50081110 Benzyl-[2-(2-trifluoromethyl-1H-benzoimidazol-4-yloxy)-ethyl]-amine::CHEMBL87192 D(2) dopamine receptor Rattus norvegicus 0.180000 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081110&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9840672 103981164 CHEMBL87192 ZINC03923630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142170 Clc1cc(OCCNCc2ccccc2)c2[nH]c(=O)[nH]c2c1 InChI=1S/C16H16ClN3O2/c17-12-8-13-15(20-16(21)19-13)14(9-12)22-7-6-18-10-11-4-2-1-3-5-11/h1-5,8-9,18H,6-7,10H2,(H2,19,20,21) YKNNRQLCQGQFRB-UHFFFAOYSA-N 50081106 4-(2-Benzylamino-ethoxy)-6-chloro-1,3-dihydro-benzoimidazol-2-one::CHEMBL329398 D(2) dopamine receptor Rattus norvegicus 0.250000 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081106&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9861786 103981160 CHEMBL329398 ZINC02008275 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50142179 O=c1[nH]c2cccc(OCCNCc3ccccc3)c2[nH]1 InChI=1S/C16H17N3O2/c20-16-18-13-7-4-8-14(15(13)19-16)21-10-9-17-11-12-5-2-1-3-6-12/h1-8,17H,9-11H2,(H2,18,19,20) MUGIIZXLOBYZRQ-UHFFFAOYSA-N 50081112 4-(2-Benzylamino-ethoxy)-1,3-dihydro-benzoimidazol-2-one::CHEMBL314174 D(2) dopamine receptor Rattus norvegicus 0.180000 ChEMBL 10.1016/s0960-894x(99)00434-5 10.7270/Q22V2FBG 10498215 Mewshaw, RE; Nelson, JA; Shah, US; Shi, X; Mazandarani, H; Coupet, J; Marquis, K; Brennan, JA; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50081112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50081112&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9817253 103981166 CHEMBL314174 ZINC02008258 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50018579 O=c1[nH]c2ccc3CC[C@@H](CNCc4ccccc4)Oc3c2[nH]1 InChI=1S/C18H19N3O2/c22-18-20-15-9-7-13-6-8-14(23-17(13)16(15)21-18)11-19-10-12-4-2-1-3-5-12/h1-5,7,9,14,19H,6,8,10-11H2,(H2,20,21,22)/t14-/m0/s1 NJDDOYGAHXQMEQ-AWEZNQCLSA-N 50109024 (S)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one::CHEMBL93753 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109024&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10470579 104004065 CHEMBL93753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50018583 O=C1Cc2c(N1)ccc1CC[C@H](CNCc3ccccc3)Oc21 InChI=1S/C19H20N2O2/c22-18-10-16-17(21-18)9-7-14-6-8-15(23-19(14)16)12-20-11-13-4-2-1-3-5-13/h1-5,7,9,15,20H,6,8,10-12H2,(H,21,22)/t15-/m1/s1 NPATVCXCHCPFCB-OAHLLOKOSA-N 50077581 (R)-2-(Benzylamino-methyl)-3,4,7,9-tetrahydro-2H-pyrano[2,3-e]indol-8-one::CHEMBL303556 D(2) dopamine receptor Rattus norvegicus 0.140000 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077581&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10063875 103970350 CHEMBL303556 ZINC13586902 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50018584 C(NCc1ccccc1)[C@H]1CCc2ccc3[nH]ccc3c2O1 InChI=1S/C19H20N2O/c1-2-4-14(5-3-1)12-20-13-16-8-6-15-7-9-18-17(10-11-21-18)19(15)22-16/h1-5,7,9-11,16,20-21H,6,8,12-13H2/t16-/m1/s1 AERWLNZHDGJKMO-MRXNPFEDSA-N 50077569 Benzyl-[(R)-1-(2,3,4,7-tetrahydro-pyrano[2,3-e]indol-2-yl)methyl]-amine::CHEMBL60185 D(2) dopamine receptor Rattus norvegicus 36 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50077569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50077569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10613605 103970338 CHEMBL60185 ZINC12356074 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50018585 O=c1[nH]c2ccc3CC[C@H](CNCc4ccccc4)Oc3c2[nH]1 InChI=1S/C18H19N3O2/c22-18-20-15-9-7-13-6-8-14(23-17(13)16(15)21-18)11-19-10-12-4-2-1-3-5-12/h1-5,7,9,14,19H,6,8,10-11H2,(H2,20,21,22)/t14-/m1/s1 NJDDOYGAHXQMEQ-CQSZACIVSA-N 50109021 (R)-8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one::CHEMBL420986 D(2) dopamine receptor Rattus norvegicus 0.070000 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109021&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9861459 104004062 CHEMBL420986 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50018587 O=c1[nH]c2ccc3CCC(CNCc4ccccc4)Oc3c2[nH]1 InChI=1S/C18H19N3O2/c22-18-20-15-9-7-13-6-8-14(23-17(13)16(15)21-18)11-19-10-12-4-2-1-3-5-12/h1-5,7,9,14,19H,6,8,10-11H2,(H2,20,21,22) NJDDOYGAHXQMEQ-UHFFFAOYSA-N 50109020 8-(Benzylamino-methyl)-3,6,7,8-tetrahydro-1H-chromeno[7,8-d]imidazol-2-one::CHEMBL93779 D(2) dopamine receptor Rattus norvegicus 7 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109020&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9948584 104004061 CHEMBL93779 ZINC13586901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50566265 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 5.0 ChEMBL 10.7270/Q2BV7JSX n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50566267 CCc1c(C)[nH]c2CCC(CCN3CCOCC3)C(=O)c12 InChI=1S/C17H26N2O2/c1-3-14-12(2)18-15-5-4-13(17(20)16(14)15)6-7-19-8-10-21-11-9-19/h13,18H,3-11H2,1-2H3 IRFDYMHWMBALRS-UHFFFAOYSA-N 50213065 CHEMBL349997::QF-0400B D(2) dopamine receptor Rattus norvegicus 589 ChEMBL 10.7270/Q2BV7JSX n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213065&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10085633 376070809 CHEMBL349997 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50566271 CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12 InChI=1S/C16H24N2O2/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18/h12,17H,3-10H2,1-2H3 KLPWJLBORRMFGK-UHFFFAOYSA-N 50130290 3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one::3-Ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one ( Molindone)::CHEMBL460::MOLINDONE::Moban D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.7270/Q2BV7JSX n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130290&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23897 104021724 CHEMBL460 DB01618 207 C07230 ZINC22002218 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50566275 CCc1c(C)[nH]c2CCC(CCN3CCN(CC3)c3ccccc3OC)C(=O)c12 InChI=1S/C24H33N3O2/c1-4-19-17(2)25-20-10-9-18(24(28)23(19)20)11-12-26-13-15-27(16-14-26)21-7-5-6-8-22(21)29-3/h5-8,18,25H,4,9-16H2,1-3H3 LHGSFGIUUOTCPG-UHFFFAOYSA-N 50409492 CHEMBL155006::QF-0402B D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.7270/Q2BV7JSX n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409492&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10000788 163358516 CHEMBL155006 ZINC13471649 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008162 Brc1ccc(N2CCN(Cc3ccccc3)CC2)c2cc[nH]c12 InChI=1S/C19H20BrN3/c20-17-6-7-18(16-8-9-21-19(16)17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-9,21H,10-14H2 RBUDKKJLRVBPDA-UHFFFAOYSA-N 50071853 4-(4-Benzyl-piperazin-1-yl)-7-bromo-1H-indole::CHEMBL90476 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071853&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323962 103965563 CHEMBL90476 ZINC26650889 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50008166 C(N1CCN(CC1)c1cccc2[nH]ccc12)c1ccccc1 InChI=1S/C19H21N3/c1-2-5-16(6-3-1)15-21-11-13-22(14-12-21)19-8-4-7-18-17(19)9-10-20-18/h1-10,20H,11-15H2 JLZIBIQTDGMAFZ-UHFFFAOYSA-N 50071857 4-(4-Benzyl-piperazin-1-yl)-1H-indole::CHEMBL328051 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071857&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2728532 103965567 CHEMBL328051 ZINC53006914 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50124110 C(N1CCN(CC1)c1cccc2[nH]cnc12)c1ccccc1 InChI=1S/C18H20N4/c1-2-5-15(6-3-1)13-21-9-11-22(12-10-21)17-8-4-7-16-18(17)20-14-19-16/h1-8,14H,9-13H2,(H,19,20) ZNBOBGDGUIWKPE-UHFFFAOYSA-N 50071852 4-(4-Benzyl-piperazin-1-yl)-1H-benzoimidazole::CHEMBL88837 D(2) dopamine receptor Rattus norvegicus 107 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071852&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323762 103965562 CHEMBL88837 ZINC26579141 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50124116 Clc1ccc2[nH]ccc2c1N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H20ClN3/c20-17-6-7-18-16(8-9-21-18)19(17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-9,21H,10-14H2 IRFLVVGRMBDQSJ-UHFFFAOYSA-N 50071858 4-(4-Benzyl-piperazin-1-yl)-5-chloro-1H-indole::CHEMBL311539 D(2) dopamine receptor Rattus norvegicus 9.1 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071858&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323978 103965568 CHEMBL311539 ZINC26580242 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50124119 Clc1ccc2NC(=O)Cc2c1N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H20ClN3O/c20-16-6-7-17-15(12-18(24)21-17)19(16)23-10-8-22(9-11-23)13-14-4-2-1-3-5-14/h1-7H,8-13H2,(H,21,24) PIPVZEXRFVHTJJ-UHFFFAOYSA-N 50071859 4-(4-Benzyl-piperazin-1-yl)-5-chloro-1,3-dihydro-indol-2-one::CHEMBL330108 D(2) dopamine receptor Rattus norvegicus 403 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323780 103965569 CHEMBL330108 ZINC26645609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50124125 O=C1Cc2c(N1)cccc2N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H21N3O/c23-19-13-16-17(20-19)7-4-8-18(16)22-11-9-21(10-12-22)14-15-5-2-1-3-6-15/h1-8H,9-14H2,(H,20,23) TUVRDSTTWFDDHW-UHFFFAOYSA-N 50071856 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-indol-2-one::CHEMBL314952 D(2) dopamine receptor Rattus norvegicus 8.1 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9995379 103965566 CHEMBL314952 ZINC26639952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50124130 O=c1[nH]c2cccc(N3CCN(Cc4ccccc4)CC3)c2[nH]1 InChI=1S/C18H20N4O/c23-18-19-15-7-4-8-16(17(15)20-18)22-11-9-21(10-12-22)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H2,19,20,23) MKJHGVZTPBBKML-UHFFFAOYSA-N 50071854 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL315864 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18414156 103965564 CHEMBL315864 ZINC26648578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50124132 FC(F)(F)c1nc2c(cccc2[nH]1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H19F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H,23,24) PSWUORNVMIRUSW-UHFFFAOYSA-N 50071855 4-(4-Benzyl-piperazin-1-yl)-2-trifluoromethyl-1H-benzoimidazole::CHEMBL88289 D(2) dopamine receptor Rattus norvegicus 0.510000 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071855&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323763 103965565 CHEMBL88289 ZINC26579142 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50124133 Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-4-7-16(13-17)19-11-9-18(10-12-19)14-15-5-2-1-3-6-15/h1-8,13,20H,9-12,14H2 BISVFNHMXVNVMG-UHFFFAOYSA-N 50069907 1-benzyl-4-(3-hydroxyphenyl)piperazine::3-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL88365 D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1016/s0960-894x(98)00474-0 10.7270/Q2C53K0X 9873601 Mewshaw, RE; Verwijs, A; Shi, X; McGaughey, GB; Nelson, JA; Mazandarani, H; Brennan, JA; Marquis, KL; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratory http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015867 103963869 CHEMBL88365 ZINC26638652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50587099 FC(F)(F)c1nc2ccc3CCC(CNCc4ccccc4)Oc3c2[nH]1 InChI=1S/C19H18F3N3O/c20-19(21,22)18-24-15-9-7-13-6-8-14(26-17(13)16(15)25-18)11-23-10-12-4-2-1-3-5-12/h1-5,7,9,14,23H,6,8,10-11H2,(H,24,25) JFFIIIVILGKQSZ-UHFFFAOYSA-N 50109019 Benzyl-(2-trifluoromethyl-3,6,7,8-tetrahydro-chromeno[7,8-d]imidazol-8-ylmethyl)-amine::CHEMBL313851 D(2) dopamine receptor Rattus norvegicus 65 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109019&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9820313 104004060 CHEMBL313851 ZINC13586899 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50577300 O[C@@H](COc1ccccc1)CN1CCC(CC1)c1ccc(Oc2ccccc2)cc1 InChI=1S/C26H29NO3/c28-23(20-29-24-7-3-1-4-8-24)19-27-17-15-22(16-18-27)21-11-13-26(14-12-21)30-25-9-5-2-6-10-25/h1-14,22-23,28H,15-20H2/t23-/m1/s1 FXLWBYZTEVJBSX-HSZRJFAPSA-N 50082319 (R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-yl]-propan-2-ol; hydrochloride::CHEMBL554228 D(2) dopamine receptor Rattus norvegicus 4080 ChEMBL 10.1016/s0960-894x(99)00516-8 10.7270/Q2D21Z3B 10571163 Annoura, H; Nakanishi, K; Uesugi, M; Fukunaga, A; Miyajima, A; Tamura-Horikawa, Y; Tamura, S Institute for Bio-Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082319 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082319&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44332705 103982122 CHEMBL554228 ZINC13836164 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50018578 Oc1ccc2CC[C@H](CNCc3ccccc3)Oc2c1 InChI=1S/C17H19NO2/c19-15-8-6-14-7-9-16(20-17(14)10-15)12-18-11-13-4-2-1-3-5-13/h1-6,8,10,16,18-19H,7,9,11-12H2/t16-/m1/s1 DWUAAOIZQFTYQP-MRXNPFEDSA-N 50061669 (R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid::CHEMBL134807::CHEMBL64553 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1016/s0960-894x(01)00778-8 10.7270/Q22J6CDZ 11814775 Mewshaw, RE; Zhao, R; Shi, X; Marquis, K; Brennan, JA; Mazandarani, H; Coupet, J; Andree, TH Wyeth-Ayerst Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50061669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50061669&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10378389 103957219 CHEMBL134807CHEMBL64553 ZINC13527706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002143 CN1CCC=C2[C@@H]1CCc1sc(N)nc21 InChI=1S/C11H15N3S/c1-14-6-2-3-7-8(14)4-5-9-10(7)13-11(12)15-9/h3,8H,2,4-6H2,1H3,(H2,12,13)/t8-/m0/s1 XFJSSDHKIXXJLM-QMMMGPOBSA-N 50279805 (S)-6-Methyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]quinolin-2-ylamine::CHEMBL348012 D(2) dopamine receptor Rattus norvegicus 202 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44367326 104121509 CHEMBL348012 ZINC05140806 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002145 C(CN1CCN(CC1)c1ccccn1)[C@@H]1CCC(=CC1)c1ccccc1 InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m0/s1 MQHGACGPMGUHSJ-FQEVSTJZSA-N 50281606 1-[2-((R)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyridin-2-yl-piperazine::CHEMBL348547::PD-137821 D(2) dopamine receptor Rattus norvegicus 545 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281606&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44372627 104123280 CHEMBL348547 ZINC27715109 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002154 C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1 MQHGACGPMGUHSJ-HXUWFJFHSA-N 50055724 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyridin-2-yl-piperazine::CHEMBL418937::PD-137789 D(2) dopamine receptor Rattus norvegicus 412 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10904165 103952206 CHEMBL418937 ZINC26575034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50559607 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 1.7 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50559753 C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1 MQHGACGPMGUHSJ-HXUWFJFHSA-N 50055724 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyridin-2-yl-piperazine::CHEMBL418937::PD-137789 D(2) dopamine receptor Rattus norvegicus 88 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10904165 103952206 CHEMBL418937 ZINC26575034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50559754 C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1 MQHGACGPMGUHSJ-HXUWFJFHSA-N 50055724 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyridin-2-yl-piperazine::CHEMBL418937::PD-137789 D(2) dopamine receptor Rattus norvegicus 704 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10904165 103952206 CHEMBL418937 ZINC26575034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50559755 C(CN1CCN(CC1)c1ccccn1)[C@H]1CCC(=CC1)c1ccccc1 InChI=1S/C23H29N3/c1-2-6-21(7-3-1)22-11-9-20(10-12-22)13-15-25-16-18-26(19-17-25)23-8-4-5-14-24-23/h1-8,11,14,20H,9-10,12-13,15-19H2/t20-/m1/s1 MQHGACGPMGUHSJ-HXUWFJFHSA-N 50055724 1-[2-((S)-4-Phenyl-cyclohex-3-enyl)-ethyl]-4-pyridin-2-yl-piperazine::CHEMBL418937::PD-137789 D(2) dopamine receptor Rattus norvegicus 82 ChEMBL 10.1016/S0960-894X(01)81245-2 10.7270/Q2222V75 Jaen, JC; Caprathe, BW; Wise, LD; Meltzer, LT; Pugsley, TA; Huffner, TG TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50055724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50055724&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10904165 103952206 CHEMBL418937 ZINC26575034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50002489 NC1Cc2cnn3cccc(C1)c23 InChI=1S/C10H11N3/c11-9-4-7-2-1-3-13-10(7)8(5-9)6-12-13/h1-3,6,9H,4-5,11H2 PRZSHWXHGWAKRK-UHFFFAOYSA-N 50282000 4,5-Dihydro-3H-pyrazolo[4,5,1-ij]quinolin-4-ylamine::CHEMBL433233 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1016/S0960-894X(00)80003-7 10.7270/Q2MS3T7B Gmeiner, P; Sommer, J; Mierau, J; Hofner, G TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50282000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50282000&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283224 104123674 CHEMBL433233 ZINC29247944 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50560190 CCCNC1Cc2cnn3cccc(C1)c23 InChI=1S/C13H17N3/c1-2-5-14-12-7-10-4-3-6-16-13(10)11(8-12)9-15-16/h3-4,6,9,12,14H,2,5,7-8H2,1H3 VYXFGMDFSNPGEX-UHFFFAOYSA-N 50281999 (4,5-Dihydro-3H-pyrazolo[4,5,1-ij]quinolin-4-yl)-propyl-amine::CHEMBL34022 D(2) dopamine receptor Rattus norvegicus >100000 ChEMBL 10.1016/S0960-894X(00)80003-7 10.7270/Q2MS3T7B Gmeiner, P; Sommer, J; Mierau, J; Hofner, G TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50281999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50281999&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44283225 104123673 CHEMBL34022 ZINC29247953 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50560191 CCCN(CCC)[C@H]1CCn2cccc2C1 InChI=1S/C14H24N2/c1-3-8-15(9-4-2)14-7-11-16-10-5-6-13(16)12-14/h5-6,10,14H,3-4,7-9,11-12H2,1-2H3/t14-/m0/s1 BCXCDTKLXHURCX-AWEZNQCLSA-N 50366327 CHEMBL192037 D(2) dopamine receptor Rattus norvegicus 7100 ChEMBL 10.1016/S0960-894X(00)80003-7 10.7270/Q2MS3T7B Gmeiner, P; Sommer, J; Mierau, J; Hofner, G TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15720219 160845429 CHEMBL192037 ZINC05833146 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50560192 CCCN(CCC)C1Cc2cnn3cccc(C1)c23 InChI=1S/C16H23N3/c1-3-7-18(8-4-2)15-10-13-6-5-9-19-16(13)14(11-15)12-17-19/h5-6,9,12,15H,3-4,7-8,10-11H2,1-2H3 NGFQETPADWIYMH-UHFFFAOYSA-N 50282001 (4,5-Dihydro-3H-pyrazolo[4,5,1-ij]quinolin-4-yl)-dipropyl-amine::CHEMBL34025 D(2) dopamine receptor Rattus norvegicus 50400 ChEMBL 10.1016/S0960-894X(00)80003-7 10.7270/Q2MS3T7B Gmeiner, P; Sommer, J; Mierau, J; Hofner, G TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50282001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50282001&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10377783 104123675 CHEMBL34025 ZINC29248050 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50566868 COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC(C1)N2C InChI=1S/C16H22ClN3O2/c1-20-10-3-4-11(20)6-9(5-10)19-16(21)12-7-13(17)14(18)8-15(12)22-2/h7-11H,3-6,18H2,1-2H3,(H,19,21) HTMNINCXKXABOI-UHFFFAOYSA-N 82519 4-amino-5-chloro-2-methoxy-N-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)benzamide::BRL 24682::CAS_76272-78-1 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/0960-894X(95)00115-A 10.7270/Q2R78FP7 Langlois, M; Yang, D; Bremont, B; Shen, S TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9797313 136350489 ZINC13493298 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50564283 CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 50018958 CHEBI:75401::QUINPIROLE D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.7270/Q2930WC4 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 103930000 ZINC13490706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50564286 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 105 ChEMBL 10.7270/Q2930WC4 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50564287 Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 InChI=1S/C16H16ClNO3/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21/h1-4,7,13,18-21H,5-6,8H2 TVURRHSHRRELCG-UHFFFAOYSA-N 60917 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::FENOLDOPAM::FENOLDOPAM MESYLATE::MLS001401388::SMR000469190::cid_49659 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.7270/Q2930WC4 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G3C 7CKW,7X2C 3341 252640133 DB00800 C07693 ZINC22116612 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50564296 Oc1ccc(C[C@@H]2CCCN2CCCCCCN2CCC[C@H]2Cc2ccc(O)c(O)c2)cc1O InChI=1S/C28H40N2O4/c31-25-11-9-21(19-27(25)33)17-23-7-5-15-29(23)13-3-1-2-4-14-30-16-6-8-24(30)18-22-10-12-26(32)28(34)20-22/h9-12,19-20,23-24,31-34H,1-8,13-18H2/t23-,24-/m0/s1 VQJOREUOQIWUDM-ZEQRLZLVSA-N 50213355 CHEMBL80686 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.7270/Q2930WC4 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44316331 376070935 CHEMBL80686 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50564297 Oc1ccc(C[C@H]2CCCN2CCCCCCN2CCC[C@@H]2Cc2ccc(O)c(O)c2)cc1O InChI=1S/C28H40N2O4/c31-25-11-9-21(19-27(25)33)17-23-7-5-15-29(23)13-3-1-2-4-14-30-16-6-8-24(30)18-22-10-12-26(32)28(34)20-22/h9-12,19-20,23-24,31-34H,1-8,13-18H2/t23-,24-/m1/s1 VQJOREUOQIWUDM-DNQXCXABSA-N 50213356 CHEMBL310997 D(2) dopamine receptor Rattus norvegicus 6.2 ChEMBL 10.7270/Q2930WC4 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9869262 376070936 CHEMBL310997 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50564300 Oc1ccc(C[C@H]2CCCN2CCCCCCN2CCC[C@H]2Cc2ccc(O)c(O)c2)cc1O InChI=1S/C28H40N2O4/c31-25-11-9-21(19-27(25)33)17-23-7-5-15-29(23)13-3-1-2-4-14-30-16-6-8-24(30)18-22-10-12-26(32)28(34)20-22/h9-12,19-20,23-24,31-34H,1-8,13-18H2/t23-,24+ VQJOREUOQIWUDM-PSWAGMNNSA-N 50213354 CHEMBL80974 D(2) dopamine receptor Rattus norvegicus 8.9 ChEMBL 10.7270/Q2930WC4 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213354&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44316058 376070934 CHEMBL80974 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50564306 CCCN(CCC)CCc1ccc(O)c(O)c1 InChI=1S/C14H23NO2/c1-3-8-15(9-4-2)10-7-12-5-6-13(16)14(17)11-12/h5-6,11,16-17H,3-4,7-10H2,1-2H3 LMYSNFBROWBKMB-UHFFFAOYSA-N 50019396 4-(2-Dipropylamino-ethyl)-benzene-1,2-diol::4-(2-Dipropylamino-ethyl)-benzene-1,2-diol (N,N-dipropyldopamine)::CHEMBL15564::N,N-di-n-Propyldopamine D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.7270/Q2930WC4 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019396&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3106 103930360 CHEMBL15564 ZINC02539818 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50564312 CCCN(CCCCCCN1CCC[C@@H]1Cc1ccc(O)c(O)c1)CCc1ccc(O)c(O)c1 InChI=1S/C28H42N2O4/c1-2-14-29(18-13-22-9-11-25(31)27(33)20-22)15-5-3-4-6-16-30-17-7-8-24(30)19-23-10-12-26(32)28(34)21-23/h9-12,20-21,24,31-34H,2-8,13-19H2,1H3/t24-/m1/s1 NGGFFSQKRFAGBP-XMMPIXPASA-N 50213353 CHEMBL308295 D(2) dopamine receptor Rattus norvegicus 3.2 ChEMBL 10.7270/Q2930WC4 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213353&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10457445 376070933 CHEMBL308295 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50564313 CCCCN1CCCC1Cc1ccc(O)c(O)c1 InChI=1S/C15H23NO2/c1-2-3-8-16-9-4-5-13(16)10-12-6-7-14(17)15(18)11-12/h6-7,11,13,17-18H,2-5,8-10H2,1H3 KPEGJUMHLTXVJK-UHFFFAOYSA-N 50213352 CHEMBL80369 D(2) dopamine receptor Rattus norvegicus 3.2 ChEMBL 10.7270/Q2930WC4 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44316024 376070932 CHEMBL80369 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544376 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C25H23Cl2FN4O3/c26-20-5-3-18(15-21(20)27)32-24(33)7-6-23(29-32)34-13-1-10-31-11-8-16(9-12-31)25-19-4-2-17(28)14-22(19)35-30-25/h2-7,14-16H,1,8-13H2 IYLWHEUTHMGJKD-UHFFFAOYSA-N 50208439 CHEMBL3884918 D(2) dopamine receptor Rattus norvegicus 7.8 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208439 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208439&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130789 375982063 CHEMBL3884918 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544377 Cc1c(C)c(=O)n(nc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)-c1ccc(Cl)c(Cl)c1 InChI=1S/C27H27Cl2FN4O3/c1-16-17(2)27(35)34(20-5-7-22(28)23(29)15-20)31-26(16)36-13-3-10-33-11-8-18(9-12-33)25-21-6-4-19(30)14-24(21)37-32-25/h4-7,14-15,18H,3,8-13H2,1-2H3 AATQZRYKNHNEDJ-UHFFFAOYSA-N 50208440 CHEMBL3883388 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208440 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208440&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131479 375982064 CHEMBL3883388 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544378 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(Cl)cc2Cl)CC1 InChI=1S/C25H23Cl2FN4O3/c26-17-2-5-21(20(27)14-17)32-24(33)7-6-23(29-32)34-13-1-10-31-11-8-16(9-12-31)25-19-4-3-18(28)15-22(19)35-30-25/h2-7,14-16H,1,8-13H2 LTNIBSBDECLTDH-UHFFFAOYSA-N 50208441 CHEMBL3885254 D(2) dopamine receptor Rattus norvegicus 0.400000 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208441 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208441&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130105 375982065 CHEMBL3885254 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544379 Fc1ccc(c(F)c1)-n1nc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)ccc1=O InChI=1S/C25H23F3N4O3/c26-17-3-5-21(20(28)14-17)32-24(33)7-6-23(29-32)34-13-1-10-31-11-8-16(9-12-31)25-19-4-2-18(27)15-22(19)35-30-25/h2-7,14-16H,1,8-13H2 OORCDDHVHSZICM-UHFFFAOYSA-N 50208442 CHEMBL3884733 D(2) dopamine receptor Rattus norvegicus 174 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208442&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130775 375982066 CHEMBL3884733 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544406 Clc1ccc(cc1Cl)-n1nc(OCCCN2CCN(CC2)c2ccccn2)ccc1=O InChI=1S/C22H23Cl2N5O2/c23-18-6-5-17(16-19(18)24)29-22(30)8-7-21(26-29)31-15-3-10-27-11-13-28(14-12-27)20-4-1-2-9-25-20/h1-2,4-9,16H,3,10-15H2 AFXWVOVMMKFRCZ-UHFFFAOYSA-N 50208443 CHEMBL3883429 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208443 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208443&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131272 375982067 CHEMBL3883429 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544407 Clc1ccc(cc1Cl)-n1nc(OCCCN2CCN(CC2)c2cccc(Cl)c2Cl)ccc1=O InChI=1S/C23H22Cl4N4O2/c24-17-6-5-16(15-19(17)26)31-22(32)8-7-21(28-31)33-14-2-9-29-10-12-30(13-11-29)20-4-1-3-18(25)23(20)27/h1,3-8,15H,2,9-14H2 KGGJBQKVVDZPQC-UHFFFAOYSA-N 50208453 CHEMBL3885327 D(2) dopamine receptor Rattus norvegicus 777 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208453&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131202 375982077 CHEMBL3885327 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544411 Clc1ccc(cc1Cl)-n1nc(OCCCN2CCC(CC2)c2c[nH]c3ccccc23)ccc1=O InChI=1S/C26H26Cl2N4O2/c27-22-7-6-19(16-23(22)28)32-26(33)9-8-25(30-32)34-15-3-12-31-13-10-18(11-14-31)21-17-29-24-5-2-1-4-20(21)24/h1-2,4-9,16-18,29H,3,10-15H2 ZRVZATYGLCRTSU-UHFFFAOYSA-N 50208457 CHEMBL3885088 D(2) dopamine receptor Rattus norvegicus 499 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208457&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130676 375982081 CHEMBL3885088 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544412 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(F)c(F)c2)CC1 InChI=1S/C25H23F3N4O3/c26-17-2-4-19-22(14-17)35-30-25(19)16-8-11-31(12-9-16)10-1-13-34-23-6-7-24(33)32(29-23)18-3-5-20(27)21(28)15-18/h2-7,14-16H,1,8-13H2 JGWNKPYNEUQGCL-UHFFFAOYSA-N 50208458 CHEMBL3884034 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208458&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131314 375982082 CHEMBL3884034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544418 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2cc(Cl)ccc2Cl)CC1 InChI=1S/C25H23Cl2FN4O3/c26-17-2-5-20(27)21(14-17)32-24(33)7-6-23(29-32)34-13-1-10-31-11-8-16(9-12-31)25-19-4-3-18(28)15-22(19)35-30-25/h2-7,14-16H,1,8-13H2 JRNSVVDDKAJZGF-UHFFFAOYSA-N 50208446 CHEMBL3884161 D(2) dopamine receptor Rattus norvegicus 2.7 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208446 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208446&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131322 375982070 CHEMBL3884161 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544422 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2ccccc2)CC1 InChI=1S/C25H25FN4O3/c26-19-7-8-21-22(17-19)33-28-25(21)18-11-14-29(15-12-18)13-4-16-32-23-9-10-24(31)30(27-23)20-5-2-1-3-6-20/h1-3,5-10,17-18H,4,11-16H2 BLNKUCXNQVZRQV-UHFFFAOYSA-N 50208445 CHEMBL3884105 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208445 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208445&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130555 375982069 CHEMBL3884105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544427 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2cccc(Cl)c2)CC1 InChI=1S/C25H24ClFN4O3/c26-18-3-1-4-20(15-18)31-24(32)8-7-23(28-31)33-14-2-11-30-12-9-17(10-13-30)25-21-6-5-19(27)16-22(21)34-29-25/h1,3-8,15-17H,2,9-14H2 RACRRVYNDQJORI-UHFFFAOYSA-N 50208463 CHEMBL3884300 D(2) dopamine receptor Rattus norvegicus 41 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208463&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131133 375982087 CHEMBL3884300 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544431 Cc1cccc(N2CCN(CCCOc3ccc(=O)n(n3)-c3ccc(Cl)c(Cl)c3)CC2)c1C InChI=1S/C25H28Cl2N4O2/c1-18-5-3-6-23(19(18)2)30-14-12-29(13-15-30)11-4-16-33-24-9-10-25(32)31(28-24)20-7-8-21(26)22(27)17-20/h3,5-10,17H,4,11-16H2,1-2H3 QSROKSRHRICBOT-UHFFFAOYSA-N 50208465 CHEMBL3883484 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130701 375982089 CHEMBL3883484 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544432 COc1ccc(cc1)N1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C24H26Cl2N4O3/c1-32-20-6-3-18(4-7-20)29-14-12-28(13-15-29)11-2-16-33-23-9-10-24(31)30(27-23)19-5-8-21(25)22(26)17-19/h3-10,17H,2,11-16H2,1H3 IDVFLIWLLOAZQZ-UHFFFAOYSA-N 50208466 CHEMBL3884619 D(2) dopamine receptor Rattus norvegicus 845 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208466&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130580 375982090 CHEMBL3884619 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544433 Clc1ccc(cc1Cl)-n1nc(OCCCN2CCN(CC2)c2ncccn2)ccc1=O InChI=1S/C21H22Cl2N6O2/c22-17-4-3-16(15-18(17)23)29-20(30)6-5-19(26-29)31-14-2-9-27-10-12-28(13-11-27)21-24-7-1-8-25-21/h1,3-8,15H,2,9-14H2 DGGUHFSQGSCQFM-UHFFFAOYSA-N 50208467 CHEMBL3883960 D(2) dopamine receptor Rattus norvegicus 914 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208467&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134129971 375982091 CHEMBL3883960 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544434 FC(F)(F)c1cccc(c1)N1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C24H23Cl2F3N4O2/c25-20-6-5-19(16-21(20)26)33-23(34)8-7-22(30-33)35-14-2-9-31-10-12-32(13-11-31)18-4-1-3-17(15-18)24(27,28)29/h1,3-8,15-16H,2,9-14H2 UEYSAAKMSNXWEY-UHFFFAOYSA-N 50208468 CHEMBL3885211 D(2) dopamine receptor Rattus norvegicus 916 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208468&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130998 375982092 CHEMBL3885211 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544435 Clc1ccc(cc1Cl)-n1nc(OCCCN2CCN(CC2)c2ccccc2Cl)ccc1=O InChI=1S/C23H23Cl3N4O2/c24-18-7-6-17(16-20(18)26)30-23(31)9-8-22(27-30)32-15-3-10-28-11-13-29(14-12-28)21-5-2-1-4-19(21)25/h1-2,4-9,16H,3,10-15H2 UMPJCGFVNPSWNW-UHFFFAOYSA-N 50208469 CHEMBL3884885 D(2) dopamine receptor Rattus norvegicus 808 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208469&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130970 375982093 CHEMBL3884885 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544436 NC(=O)c1ccc2occ(N3CCN(CCCOc4ccc(=O)n(n4)-c4ccc(Cl)c(Cl)c4)CC3)c2c1 InChI=1S/C26H25Cl2N5O4/c27-20-4-3-18(15-21(20)28)33-25(34)7-6-24(30-33)36-13-1-8-31-9-11-32(12-10-31)22-16-37-23-5-2-17(26(29)35)14-19(22)23/h2-7,14-16H,1,8-13H2,(H2,29,35) HLUAULUWRFMZCS-UHFFFAOYSA-N 50208459 CHEMBL3884820 D(2) dopamine receptor Rattus norvegicus 379 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208459&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130433 375982083 CHEMBL3884820 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544437 Clc1ccc(cc1Cl)-n1nc(OCCCN2CCC(CC2)c2nc3ccccc3s2)ccc1=O InChI=1S/C25H24Cl2N4O2S/c26-19-7-6-18(16-20(19)27)31-24(32)9-8-23(29-31)33-15-3-12-30-13-10-17(11-14-30)25-28-21-4-1-2-5-22(21)34-25/h1-2,4-9,16-17H,3,10-15H2 VYAFRFWCZFARDY-UHFFFAOYSA-N 50208454 CHEMBL3885152 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208454&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130132 375982078 CHEMBL3885152 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544438 Fc1ccc(cc1)C(=O)C1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C25H24Cl2FN3O3/c26-21-7-6-20(16-22(21)27)31-24(32)9-8-23(29-31)34-15-1-12-30-13-10-18(11-14-30)25(33)17-2-4-19(28)5-3-17/h2-9,16,18H,1,10-15H2 RJOWWGJJQYOVOJ-UHFFFAOYSA-N 50208470 CHEMBL3885003 D(2) dopamine receptor Rattus norvegicus 179 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208470&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131035 375982094 CHEMBL3885003 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544439 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3.7 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544443 Cc1ccc(cc1)-n1nc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)ccc1=O InChI=1S/C26H27FN4O3/c1-18-3-6-21(7-4-18)31-25(32)10-9-24(28-31)33-16-2-13-30-14-11-19(12-15-30)26-22-8-5-20(27)17-23(22)34-29-26/h3-10,17,19H,2,11-16H2,1H3 OOFUYMWCXSZCMQ-UHFFFAOYSA-N 50208449 CHEMBL3883603 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208449&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130534 375982073 CHEMBL3883603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544447 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2ccc3ccccc3c2)CC1 InChI=1S/C29H27FN4O3/c30-23-7-9-25-26(19-23)37-32-29(25)21-12-15-33(16-13-21)14-3-17-36-27-10-11-28(35)34(31-27)24-8-6-20-4-1-2-5-22(20)18-24/h1-2,4-11,18-19,21H,3,12-17H2 OBXWYCFPQDIBPF-UHFFFAOYSA-N 50208471 CHEMBL3884183 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208471&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130558 375982095 CHEMBL3884183 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544448 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2ccccc2Cl)CC1 InChI=1S/C25H24ClFN4O3/c26-20-4-1-2-5-21(20)31-24(32)9-8-23(28-31)33-15-3-12-30-13-10-17(11-14-30)25-19-7-6-18(27)16-22(19)34-29-25/h1-2,4-9,16-17H,3,10-15H2 UPBAPPUQVHJHCB-UHFFFAOYSA-N 50208455 CHEMBL3884681 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208455&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130954 375982079 CHEMBL3884681 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544449 Fc1ccc(F)c(c1)-n1nc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)ccc1=O InChI=1S/C25H23F3N4O3/c26-17-3-5-20(28)21(14-17)32-24(33)7-6-23(29-32)34-13-1-10-31-11-8-16(9-12-31)25-19-4-2-18(27)15-22(19)35-30-25/h2-7,14-16H,1,8-13H2 YGAQJVYCLILFBJ-UHFFFAOYSA-N 50208460 CHEMBL3884325 D(2) dopamine receptor Rattus norvegicus 6.1 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208460&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130753 375982084 CHEMBL3884325 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544503 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2c(F)cccc2F)CC1 InChI=1S/C25H23F3N4O3/c26-17-5-6-18-21(15-17)35-30-24(18)16-9-12-31(13-10-16)11-2-14-34-22-7-8-23(33)32(29-22)25-19(27)3-1-4-20(25)28/h1,3-8,15-16H,2,9-14H2 JCSJNNBJTFWLCL-UHFFFAOYSA-N 50208447 CHEMBL3883955 D(2) dopamine receptor Rattus norvegicus 0.500000 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208447 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208447&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131472 375982071 CHEMBL3883955 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544504 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2cc(F)cc(F)c2)CC1 InChI=1S/C25H23F3N4O3/c26-17-2-3-21-22(15-17)35-30-25(21)16-6-9-31(10-7-16)8-1-11-34-23-4-5-24(33)32(29-23)20-13-18(27)12-19(28)14-20/h2-5,12-16H,1,6-11H2 YVADVWYZGONKAS-UHFFFAOYSA-N 50208464 CHEMBL3884994 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208464&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130496 375982088 CHEMBL3884994 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544638 Clc1ccc(cc1Cl)-n1nc(OCCCN2CCN(CC2)c2ccccc2)ccc1=O InChI=1S/C23H24Cl2N4O2/c24-20-8-7-19(17-21(20)25)29-23(30)10-9-22(26-29)31-16-4-11-27-12-14-28(15-13-27)18-5-2-1-3-6-18/h1-3,5-10,17H,4,11-16H2 HUXHBEGYQBJFSN-UHFFFAOYSA-N 50208462 CHEMBL3885180 D(2) dopamine receptor Rattus norvegicus 1322 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208462&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131052 375982086 CHEMBL3885180 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544639 Fc1ccc2c(noc2c1)C1CCN(CCCCCOc2ccc(=O)n(n2)-c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C27H27Cl2FN4O3/c28-22-7-5-20(17-23(22)29)34-26(35)9-8-25(31-34)36-15-3-1-2-12-33-13-10-18(11-14-33)27-21-6-4-19(30)16-24(21)37-32-27/h4-9,16-18H,1-3,10-15H2 UTRVZYIOIFYJIT-UHFFFAOYSA-N 50208479 CHEMBL3883511 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208479&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130876 375982100 CHEMBL3883511 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544646 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(F)c(Cl)c2)CC1 InChI=1S/C25H23ClF2N4O3/c26-20-15-18(3-5-21(20)28)32-24(33)7-6-23(29-32)34-13-1-10-31-11-8-16(9-12-31)25-19-4-2-17(27)14-22(19)35-30-25/h2-7,14-16H,1,8-13H2 JOQJXCCHSGZUTC-UHFFFAOYSA-N 50208450 CHEMBL3883557 D(2) dopamine receptor Rattus norvegicus 45 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208450&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134129986 375982074 CHEMBL3883557 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544657 Clc1ccc(cc1Cl)-n1nc(OCCCN2CCN(Cc3ccccc3)CC2)ccc1=O InChI=1S/C24H26Cl2N4O2/c25-21-8-7-20(17-22(21)26)30-24(31)10-9-23(27-30)32-16-4-11-28-12-14-29(15-13-28)18-19-5-2-1-3-6-19/h1-3,5-10,17H,4,11-16,18H2 RWHYEHYPRKFBDK-UHFFFAOYSA-N 50208473 CHEMBL3884581 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130948 375982097 CHEMBL3884581 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544658 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2cccc(Cl)c2Cl)CC1 InChI=1S/C25H23Cl2FN4O3/c26-19-3-1-4-20(24(19)27)32-23(33)8-7-22(29-32)34-14-2-11-31-12-9-16(10-13-31)25-18-6-5-17(28)15-21(18)35-30-25/h1,3-8,15-16H,2,9-14H2 MJNIHQSWWWZHAP-UHFFFAOYSA-N 50208451 CHEMBL3885471 D(2) dopamine receptor Rattus norvegicus 0.200000 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208451&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130475 375982075 CHEMBL3885471 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544661 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(Cl)cc2)CC1 InChI=1S/C25H24ClFN4O3/c26-18-2-5-20(6-3-18)31-24(32)9-8-23(28-31)33-15-1-12-30-13-10-17(11-14-30)25-21-7-4-19(27)16-22(21)34-29-25/h2-9,16-17H,1,10-15H2 LIOGFUGTDWLVAP-UHFFFAOYSA-N 50208477 CHEMBL3883408 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208477&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130528 375982099 CHEMBL3883408 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544664 Fc1ccc(cc1)N1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C23H23Cl2FN4O2/c24-20-7-6-19(16-21(20)25)30-23(31)9-8-22(27-30)32-15-1-10-28-11-13-29(14-12-28)18-4-2-17(26)3-5-18/h2-9,16H,1,10-15H2 ANAAEVFNRAOJLN-UHFFFAOYSA-N 50208483 CHEMBL3883495 D(2) dopamine receptor Rattus norvegicus 953 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208483&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131278 375982102 CHEMBL3883495 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544665 Fc1ccc(cc1)-n1nc(OCCCN2CCC(CC2)c2noc3cc(F)ccc23)ccc1=O InChI=1S/C25H24F2N4O3/c26-18-2-5-20(6-3-18)31-24(32)9-8-23(28-31)33-15-1-12-30-13-10-17(11-14-30)25-21-7-4-19(27)16-22(21)34-29-25/h2-9,16-17H,1,10-15H2 XMQBHZYQXIXODK-UHFFFAOYSA-N 50208452 CHEMBL3884874 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208452&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130606 375982076 CHEMBL3884874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544666 COc1ccccc1N1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C24H26Cl2N4O3/c1-32-22-6-3-2-5-21(22)29-14-12-28(13-15-29)11-4-16-33-23-9-10-24(31)30(27-23)18-7-8-19(25)20(26)17-18/h2-3,5-10,17H,4,11-16H2,1H3 NKKNGELLXVETMM-UHFFFAOYSA-N 50208481 CHEMBL3883773 D(2) dopamine receptor Rattus norvegicus 524 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208481&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130721 375982101 CHEMBL3883773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544667 Fc1ccccc1N1CCN(CCCOc2ccc(=O)n(n2)-c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C23H23Cl2FN4O2/c24-18-7-6-17(16-19(18)25)30-23(31)9-8-22(27-30)32-15-3-10-28-11-13-29(14-12-28)21-5-2-1-4-20(21)26/h1-2,4-9,16H,3,10-15H2 SACUYQYCMVJGOF-UHFFFAOYSA-N 50208472 CHEMBL3884209 D(2) dopamine receptor Rattus norvegicus 1196 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208472&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131545 375982096 CHEMBL3884209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544668 Clc1ccc(cc1Cl)-n1nc(OCCCN2CCN(CC2)c2csc3ccccc23)ccc1=O InChI=1S/C25H24Cl2N4O2S/c26-20-7-6-18(16-21(20)27)31-25(32)9-8-24(28-31)33-15-3-10-29-11-13-30(14-12-29)22-17-34-23-5-2-1-4-19(22)23/h1-2,4-9,16-17H,3,10-15H2 WFPKZCSWKHZBMW-UHFFFAOYSA-N 50208444 CHEMBL3884545 D(2) dopamine receptor Rattus norvegicus 648 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208444 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208444&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131332 375982068 CHEMBL3884545 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544669 Fc1ccc2c(noc2c1)C1CCN(CCCCOc2ccc(=O)n(n2)-c2ccc(Cl)c(Cl)c2)CC1 InChI=1S/C26H25Cl2FN4O3/c27-21-6-4-19(16-22(21)28)33-25(34)8-7-24(30-33)35-14-2-1-11-32-12-9-17(10-13-32)26-20-5-3-18(29)15-23(20)36-31-26/h3-8,15-17H,1-2,9-14H2 GHTCUTDLPUFFNC-UHFFFAOYSA-N 50208456 CHEMBL3884138 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208456&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130380 375982080 CHEMBL3884138 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544670 Fc1ccc2c(noc2c1)C1CCN(CCCOc2nn(-c3ccc(Cl)c(Cl)c3)c(=O)c3ccccc23)CC1 InChI=1S/C29H25Cl2FN4O3/c30-24-9-7-20(17-25(24)31)36-29(37)22-5-2-1-4-21(22)28(33-36)38-15-3-12-35-13-10-18(11-14-35)27-23-8-6-19(32)16-26(23)39-34-27/h1-2,4-9,16-18H,3,10-15H2 MBONXCLAMMNLIZ-UHFFFAOYSA-N 50208485 CHEMBL3883942 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208485&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134131060 375982103 CHEMBL3883942 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544685 Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2cc(Cl)cc(Cl)c2)CC1 InChI=1S/C25H23Cl2FN4O3/c26-17-12-18(27)14-20(13-17)32-24(33)5-4-23(29-32)34-11-1-8-31-9-6-16(7-10-31)25-21-3-2-19(28)15-22(21)35-30-25/h2-5,12-16H,1,6-11H2 JVABRSGCXNDWBQ-UHFFFAOYSA-N 50208474 CHEMBL3884066 D(2) dopamine receptor Rattus norvegicus 38 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208474&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130902 375982098 CHEMBL3884066 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544802 Clc1ccc(cc1Cl)-n1nc(OCCCN2CCN(CC2)c2nsc3ccccc23)ccc1=O InChI=1S/C24H23Cl2N5O2S/c25-19-7-6-17(16-20(19)26)31-23(32)9-8-22(27-31)33-15-3-10-29-11-13-30(14-12-29)24-18-4-1-2-5-21(18)34-28-24/h1-2,4-9,16H,3,10-15H2 JRPIYPHLXOIWDS-UHFFFAOYSA-N 50208448 CHEMBL3885016 D(2) dopamine receptor Rattus norvegicus 595 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208448 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208448&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134129949 375982072 CHEMBL3885016 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50544806 Fc1ccc2c(noc2c1)C1CCN(CCCOc2nn(-c3ccc(Cl)c(Cl)c3)c(=O)c3CCCCc23)CC1 InChI=1S/C29H29Cl2FN4O3/c30-24-9-7-20(17-25(24)31)36-29(37)22-5-2-1-4-21(22)28(33-36)38-15-3-12-35-13-10-18(11-14-35)27-23-8-6-19(32)16-26(23)39-34-27/h6-9,16-18H,1-5,10-15H2 PGIHYZYFXHVWLJ-UHFFFAOYSA-N 50208461 CHEMBL3884065 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1016/j.ejmech.2016.09.008 10.7270/Q2SQ92C5 27639363 Cao, X; Chen, Y; Zhang, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208461&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 134130743 375982085 CHEMBL3884065 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50555987 CN1CCN(CC1)C1=Cn2cccc2Sc2ccccc12 InChI=1S/C17H19N3S/c1-18-9-11-19(12-10-18)15-13-20-8-4-7-17(20)21-16-6-3-2-5-14(15)16/h2-8,13H,9-12H2,1H3 JFLBTRDHDHTNGX-UHFFFAOYSA-N 50137976 9-(4-Methyl-piperazin-1-yl)-4-thia-10a-aza-benzo[f]azulene::CHEMBL367045 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1021/jm0309811 10.7270/Q2VM4CRH 14695828 Campiani, G; Butini, S; Fattorusso, C; Catalanotti, B; Gemma, S; Nacci, V; Morelli, E; Cagnotto, A; Mereghetti, I; Mennini, T; Carli, M; Minetti, P; Di Cesare, MA; Mastroianni, D; Scafetta, N; Galletti, B; Stasi, MA; Castorina, M; Pacifici, L; Vertechy, M; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Universit£ degli Studi di Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50137976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50137976&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9796255 104028114 CHEMBL367045 ZINC28014373 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029315 C(Cc1ccc2ccccc2n1)N1CCc2c(C1)[nH]c1ccccc21 InChI=1S/C22H21N3/c1-3-7-20-16(5-1)9-10-17(23-20)11-13-25-14-12-19-18-6-2-4-8-21(18)24-22(19)15-25/h1-10,24H,11-15H2 CJBOQCANXATUMA-UHFFFAOYSA-N 50019750 2-(2-Quinolin-2-yl-ethyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL274781 D(2) dopamine receptor Rattus norvegicus 211 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019750&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15599287 103930673 CHEMBL274781 ZINC34602035 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029327 C(CCc1ccc2ccccc2n1)CN1CCc2c(C1)[nH]c1ccccc21 InChI=1S/C24H25N3/c1-3-10-22-18(7-1)12-13-19(25-22)8-5-6-15-27-16-14-21-20-9-2-4-11-23(20)26-24(21)17-27/h1-4,7,9-13,26H,5-6,8,14-17H2 WKXZOEAHOWJCTL-UHFFFAOYSA-N 50019738 2-(4-Quinolin-2-yl-butyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL12533 D(2) dopamine receptor Rattus norvegicus 139 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019738&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15599290 103930661 CHEMBL12533 ZINC34602038 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50029329 C(CCc1ccncc1)CN1CCc2c(C1)[nH]c1ccccc21 InChI=1S/C20H23N3/c1-2-7-19-17(6-1)18-10-14-23(15-20(18)22-19)13-4-3-5-16-8-11-21-12-9-16/h1-2,6-9,11-12,22H,3-5,10,13-15H2 RZPOTXDVVTUINK-UHFFFAOYSA-N 50019749 2-(4-Pyridin-4-yl-butyl)-2,3,4,9-tetrahydro-1H-beta-carboline::CHEMBL274446 D(2) dopamine receptor Rattus norvegicus 680 ChEMBL 10.1021/jm00389a022 10.7270/Q2K35SNV 2884314 Abou-Gharbia, M; Patel, UR; Moyer, JA; Muth, EA TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50019749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50019749&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15599286 103930672 CHEMBL274446 ZINC34602034 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50619534 Fc1ccc(cc1)[C@@H]1C[C@@H](N2CCN(CCN3CCNC3=O)CC2)c2ccccc12 InChI=1S/C24H29FN4O/c25-19-7-5-18(6-8-19)22-17-23(21-4-2-1-3-20(21)22)28-14-11-27(12-15-28)13-16-29-10-9-26-24(29)30/h1-8,22-23H,9-17H2,(H,26,30)/t22-,23+/m0/s1 GHAMYXPEZSUOCU-XZOQPEGZSA-N 50020232 1-(2-{4-[(1R,3S)-3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one::1-(2-{4-[3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-imidazolidin-2-one(Irindalone)::CHEMBL73461::Irindalone D(2) dopamine receptor Rattus norvegicus 400 ChEMBL 10.1021/jm00120a003 10.7270/Q2JQ11K7 2903929 Bogeso, KP; Arnt, J; Boeck, V; Christensen, AV; Hyttel, J; Jensen, KG H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020232&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65845 103931146 CHEMBL73461 ZINC22463226 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031698 CCN1CCC[C@H]1CNC(=O)c1c(O)cccc1OC InChI=1S/C15H22N2O3/c1-3-17-9-5-6-11(17)10-16-15(19)14-12(18)7-4-8-13(14)20-2/h4,7-8,11,18H,3,5-6,9-10H2,1-2H3,(H,16,19)/t11-/m0/s1 MVWKVVFFVMXULU-NSHDSACASA-N 50012964 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::CHEMBL8945::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (BZM) D(2) dopamine receptor Rattus norvegicus 31 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012964&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10956830 103925212 CHEMBL8945 ZINC05851787 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50620671 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 7.1 ChEMBL 10.1021/jm00400a027 10.7270/Q2C24X1V 2966245 Kung, HF; Kasliwal, R; Pan, SG; Kung, MP; Mach, RH; Guo, YZ University of Pennsylvania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031715 O=C1CC2(CCCC2)CC(=O)N1CCCCNC[C@@H]1COc2ccccc2O1 InChI=1S/C22H30N2O4/c25-20-13-22(9-3-4-10-22)14-21(26)24(20)12-6-5-11-23-15-17-16-27-18-7-1-2-8-19(18)28-17/h1-2,7-8,17,23H,3-6,9-16H2/t17-/m1/s1 HCVRCHQFYYZPHT-QGZVFWFLSA-N 50421835 CHEMBL12124 D(2) dopamine receptor Rattus norvegicus 2512 ChEMBL 10.1021/jm00401a007 10.7270/Q20Z74K6 3373482 Hibert, MF; Gittos, MW; Middlemiss, DN; Mir, AK; Fozard, JR Merrell Dow Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421835&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 23786480 164150710 CHEMBL12124 ZINC03995603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50617664 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.8 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50617677 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 118 ChEMBL 10.1021/jm00393a023 10.7270/Q2NS0VG2 2888898 Abou-Gharbia, M; Patel, UR; Webb, MB; Moyer, JA; Andree, TH; Muth, EA Wyeth Laboratories, Inc. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50618164 Oc1ccc2CCC3NCCCC3c2c1 InChI=1S/C13H17NO/c15-10-5-3-9-4-6-13-11(12(9)8-10)2-1-7-14-13/h3,5,8,11,13-15H,1-2,4,6-7H2 IETCXPRUYLQUEH-UHFFFAOYSA-N 50018652 1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-9-ol::CHEMBL56630::rac-1,2,3,4,4a,5,6,10b-Octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 30400 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018652&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039966 103929744 CHEMBL56630 ZINC29558948 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50618166 CCCN1CCCC2C1CCc1ccc(O)cc21 InChI=1S/C16H23NO/c1-2-9-17-10-3-4-14-15-11-13(18)7-5-12(15)6-8-16(14)17/h5,7,11,14,16,18H,2-4,6,8-10H2,1H3 LGRLJXCJYMYBLM-UHFFFAOYSA-N 50018643 (R,R)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol::(S,S)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol::4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol::CHEMBL67583::rac-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039976 103929735 CHEMBL67583 ZINC26275274 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50618167 CCCN1CCCC2C1CCc1ccc(O)cc21 InChI=1S/C16H23NO/c1-2-9-17-10-3-4-14-15-11-13(18)7-5-12(15)6-8-16(14)17/h5,7,11,14,16,18H,2-4,6,8-10H2,1H3 LGRLJXCJYMYBLM-UHFFFAOYSA-N 50018643 (R,R)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol::(S,S)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol::4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol::CHEMBL67583::rac-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 101 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018643&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039976 103929735 CHEMBL67583 ZINC26275274 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50618168 CCCN1CCCC2C1CCc1cc(O)ccc21 InChI=1S/C16H23NO/c1-2-9-17-10-3-4-15-14-7-6-13(18)11-12(14)5-8-16(15)17/h6-7,11,15-16,18H,2-5,8-10H2,1H3 BGWNOOWFGJBORE-UHFFFAOYSA-N 50018654 4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-8-ol::CHEMBL67584::rac-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-8-ol D(2) dopamine receptor Rattus norvegicus 730 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018654&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039992 103929746 CHEMBL67584 ZINC26275285 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50618169 CCCCN1CCCC2C1CCc1ccc(O)cc21 InChI=1S/C17H25NO/c1-2-3-10-18-11-4-5-15-16-12-14(19)8-6-13(16)7-9-17(15)18/h6,8,12,15,17,19H,2-5,7,9-11H2,1H3 ZIUSEXYMNHXTCK-UHFFFAOYSA-N 50018644 CHEMBL68432::rac-4-Butyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol D(2) dopamine receptor Rattus norvegicus 2990 ChEMBL 10.1021/jm00395a002 10.7270/Q2MW2HQJ 2824773 Wikstrom, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B University of G£teborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018644 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018644&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14039982 103929736 CHEMBL68432 ZINC26275263 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031792 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC(C)C(C)O InChI=1S/C17H28ClN3O3/c1-5-21(6-2)8-7-20-17(23)13-9-14(18)15(19)10-16(13)24-12(4)11(3)22/h9-12,22H,5-8,19H2,1-4H3,(H,20,23) NDZDJUSQBJHCBF-UHFFFAOYSA-N 50023802 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-1-methyl-propoxy)-benzamide::CHEMBL289740::erythro-4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-1-methyl-propoxy)-benzamide::threo-4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-hydroxy-1-methyl-propoxy)-benzamide D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50023802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50023802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116911 103934102 CHEMBL289740 ZINC13885312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50622958 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC[C@@H](C)O InChI=1S/C16H26ClN3O3/c1-4-20(5-2)7-6-19-16(22)12-8-13(17)14(18)9-15(12)23-10-11(3)21/h8-9,11,21H,4-7,10,18H2,1-3H3,(H,19,22)/t11-/m1/s1 GATCOSFCYSJURA-LLVKDONJSA-N 50452525 CHEMBL2114431 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00403a011 10.7270/Q25B032R 3397992 Monkovic, I; Willner, D; Adam, MA; Brown, M; Crenshaw, RR; Fuller, CE; Juby, PF; Luke, GM; Matiskella, JA; Montzka, TA Bristol-Myers Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14116909 225145705 CHEMBL2114431 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010576 CCCCCCC1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C16H25NO3/c1-2-3-4-5-6-11-9-13-12(15(10-17)20-11)7-8-14(18)16(13)19/h7-8,11,15,18-19H,2-6,9-10,17H2,1H3/t11?,15-/m0/s1 HMYHFTUKXYGDQG-MHTVFEQDSA-N 50007146 1-Aminomethyl-3-hexyl-isochroman-5,6-diol::CHEMBL420972 D(2) dopamine receptor Rattus norvegicus 5540 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007146&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320116 103920429 CHEMBL420972 ZINC26573749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010584 NC[C@@H]1OC(COc2ccccc2)Cc2c(O)c(O)ccc12 InChI=1S/C17H19NO4/c18-9-16-13-6-7-15(19)17(20)14(13)8-12(22-16)10-21-11-4-2-1-3-5-11/h1-7,12,16,19-20H,8-10,18H2/t12?,16-/m0/s1 KOHDNXKBNHHXKQ-INSVYWFGSA-N 50007130 1-Aminomethyl-3-phenoxymethyl-isochroman-5,6-diol::CHEMBL86576 D(2) dopamine receptor Rattus norvegicus 1280 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007130&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320267 103920413 CHEMBL86576 ZINC26576192 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010593 NC[C@@H]1OCCc2c(O)c(O)ccc12 InChI=1S/C10H13NO3/c11-5-9-6-1-2-8(12)10(13)7(6)3-4-14-9/h1-2,9,12-13H,3-5,11H2/t9-/m0/s1 JBSRTZUQAXYSQB-VIFPVBQESA-N 50007135 1-Aminomethyl-isochroman-5,6-diol::CHEMBL87958 D(2) dopamine receptor Rattus norvegicus 4610 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007135&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13864380 103920418 CHEMBL87958 ZINC11422303 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010603 COc1ccc(CC2Cc3c(O)c(O)ccc3[C@H](CN)O2)cc1 InChI=1S/C18H21NO4/c1-22-12-4-2-11(3-5-12)8-13-9-15-14(17(10-19)23-13)6-7-16(20)18(15)21/h2-7,13,17,20-21H,8-10,19H2,1H3/t13?,17-/m0/s1 XSPPZAPYKHJYHP-RUINGEJQSA-N 50007143 1-Aminomethyl-3-(4-methoxy-benzyl)-isochroman-5,6-diol::CHEMBL87897 D(2) dopamine receptor Rattus norvegicus 2710 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007143&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320218 103920426 CHEMBL87897 ZINC26576269 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010611 Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2/t14-/m1/s1 JUDKOGFHZYMDMF-CQSZACIVSA-N 50004822 (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::(R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)::7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)::CHEMBL1467585::CHEMBL24077::R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol::SK&F-383933::SK-38393::SK-383933::SKF 38393::SKF 38393 (+) D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004822&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6852376 103918369 CHEMBL1467585CHEMBL24077 ZINC01996374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010614 CN(CC=C)C[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C20H29NO3/c1-3-11-21(2)13-19-15-9-10-17(22)20(23)16(15)12-18(24-19)14-7-5-4-6-8-14/h3,9-10,14,18-19,22-23H,1,4-8,11-13H2,2H3/t18?,19-/m0/s1 JJNYVWDKXCESON-GGYWPGCISA-N 50007124 1-[(Allyl-methyl-amino)-methyl]-3-cyclohexyl-isochroman-5,6-diol::CHEMBL84557 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007124&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319915 103920407 CHEMBL84557 ZINC26569466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010649 NC[C@@H]1OC(Cc2ccccc2)Cc2c(O)c(O)ccc12 InChI=1S/C17H19NO3/c18-10-16-13-6-7-15(19)17(20)14(13)9-12(21-16)8-11-4-2-1-3-5-11/h1-7,12,16,19-20H,8-10,18H2/t12?,16-/m0/s1 XVBBSQGJSIEXFQ-INSVYWFGSA-N 50007150 1-Aminomethyl-3-benzyl-isochroman-5,6-diol::CHEMBL87910 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320076 103920433 CHEMBL87910 ZINC26575753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010651 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)c1cccc(O)c1 InChI=1S/C16H17NO4/c17-8-15-11-4-5-13(19)16(20)12(11)7-14(21-15)9-2-1-3-10(18)6-9/h1-6,14-15,18-20H,7-8,17H2/t14?,15-/m0/s1 SVFKIIFLKICBPG-LOACHALJSA-N 50007137 1-Aminomethyl-3-(3-hydroxy-phenyl)-isochroman-5,6-diol::CHEMBL87734 D(2) dopamine receptor Rattus norvegicus 192 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007137&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320357 103920420 CHEMBL87734 ZINC26575470 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010653 CNC[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C17H25NO3/c1-18-10-16-12-7-8-14(19)17(20)13(12)9-15(21-16)11-5-3-2-4-6-11/h7-8,11,15-16,18-20H,2-6,9-10H2,1H3/t15?,16-/m0/s1 CQTDHZQZXNNVLA-LYKKTTPLSA-N 50007125 3-Cyclohexyl-1-methylaminomethyl-isochroman-5,6-diol::CHEMBL315750 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007125&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320024 103920408 CHEMBL315750 ZINC26574942 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010666 OCCCNC[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C19H29NO4/c21-10-4-9-20-12-18-14-7-8-16(22)19(23)15(14)11-17(24-18)13-5-2-1-3-6-13/h7-8,13,17-18,20-23H,1-6,9-12H2/t17?,18-/m0/s1 CUYXSVNDDNBRBL-ZVAWYAOSSA-N 50007131 3-Cyclohexyl-1-[(3-hydroxy-propylamino)-methyl]-isochroman-5,6-diol::CHEMBL85552 D(2) dopamine receptor Rattus norvegicus 12300 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007131&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319988 103920414 CHEMBL85552 ZINC26573613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010691 CC[C@@H]1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C12H17NO3/c1-2-7-5-9-8(11(6-13)16-7)3-4-10(14)12(9)15/h3-4,7,11,14-15H,2,5-6,13H2,1H3/t7-,11+/m1/s1 YNUUJSAVGPCWBG-HQJQHLMTSA-N 50453079 CHEMBL2115213 D(2) dopamine receptor Rattus norvegicus 10800 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453079&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15696481 225145841 CHEMBL2115213 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010692 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C16H23NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h6-7,10,14-15,18-19H,1-5,8-9,17H2/t14?,15-/m0/s1 BOKASTZDGGZFET-LOACHALJSA-N 50007148 1-Aminomethyl-3-cyclohexyl-isochroman-5,6-diol::CHEMBL314459 D(2) dopamine receptor Rattus norvegicus 7030 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007148&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320050 103920431 CHEMBL314459 ZINC26575279 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033924 COc1cccc(c1)C1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C17H19NO4/c1-21-11-4-2-3-10(7-11)15-8-13-12(16(9-18)22-15)5-6-14(19)17(13)20/h2-7,15-16,19-20H,8-9,18H2,1H3/t15?,16-/m0/s1 GKRQKKOXKDSLTJ-LYKKTTPLSA-N 50007139 1-Aminomethyl-3-(3-methoxy-phenyl)-isochroman-5,6-diol::CHEMBL315005 D(2) dopamine receptor Rattus norvegicus 764 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007139&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44319976 103920422 CHEMBL315005 ZINC26571642 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033925 NC[C@H]1O[C@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m1/s1 SUHGRZPINGKYNV-HUUCEWRRSA-N 50007136 1-Aminomethyl-3-phenyl-isochroman-5,6-diol::CHEMBL83080 D(2) dopamine receptor Rattus norvegicus 2850 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007136&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14809026 103920419 CHEMBL83080 ZINC04637270 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033927 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14?,15-/m0/s1 SUHGRZPINGKYNV-LOACHALJSA-N 50007134 1-Aminomethyl-3-phenyl-isochroman-5,6-diol::CHEMBL315468 D(2) dopamine receptor Rattus norvegicus 3910 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007134&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14809027 103920417 CHEMBL315468 ZINC06885604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033929 CC(C)(C)C1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C14H21NO3/c1-14(2,3)12-6-9-8(11(7-15)18-12)4-5-10(16)13(9)17/h4-5,11-12,16-17H,6-7,15H2,1-3H3/t11-,12?/m0/s1 OOZQGBSETLAPCT-PXYINDEMSA-N 50007126 1-Aminomethyl-3-tert-butyl-isochroman-5,6-diol::CHEMBL82899 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007126&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320053 103920409 CHEMBL82899 ZINC26571262 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650700 NC[C@@H]1OC(CC#C)Cc2c(O)c(O)ccc12 InChI=1S/C13H15NO3/c1-2-3-8-6-10-9(12(7-14)17-8)4-5-11(15)13(10)16/h1,4-5,8,12,15-16H,3,6-7,14H2/t8?,12-/m0/s1 LWUHQVZWIKZZFZ-MYIOLCAUSA-N 50007151 1-Aminomethyl-3-prop-2-ynyl-isochroman-5,6-diol::CHEMBL315849 D(2) dopamine receptor Rattus norvegicus 286 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007151&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320123 103920434 CHEMBL315849 ZINC26575532 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650716 NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c1ccccc1 InChI=1S/C16H17NO3/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10/h1-7,14-15,18-19H,8-9,17H2/t14-,15-/m0/s1 SUHGRZPINGKYNV-GJZGRUSLSA-N 50007129 (1R,3S)-1-Aminomethyl-3-phenyl-isochroman-5,6-diol::1-Aminomethyl-3-phenyl-isochroman-5,6-diol::A-70108::CHEMBL86931 D(2) dopamine receptor Rattus norvegicus 807 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122324 103920412 CHEMBL86931 6077 ZINC03787668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650728 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 InChI=1S/C20H27NO3/c21-10-17-14-1-2-16(22)19(23)15(14)6-18(24-17)20-7-11-3-12(8-20)5-13(4-11)9-20/h1-2,11-13,17-18,22-23H,3-10,21H2/t11-,12+,13-,17-,18?,20?/m0/s1 QLJOSZATCBCBDR-UAKDSABFSA-N 50007147 3-Adamantan-1-yl-1-aminomethyl-isochroman-5,6-diol::CHEMBL313530 D(2) dopamine receptor Rattus norvegicus 1290 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007147&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 64638 103920430 CHEMBL313530 ZINC03871344 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650733 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)c1ccc(Br)cc1 InChI=1S/C16H16BrNO3/c17-10-3-1-9(2-4-10)14-7-12-11(15(8-18)21-14)5-6-13(19)16(12)20/h1-6,14-15,19-20H,7-8,18H2/t14?,15-/m0/s1 LDLAWZLGWDENOK-LOACHALJSA-N 50007123 1-Aminomethyl-3-(4-bromo-phenyl)-isochroman-5,6-diol::CHEMBL415080 D(2) dopamine receptor Rattus norvegicus 2090 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007123&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320092 103920406 CHEMBL415080 ZINC26570699 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650734 NC[C@@H]1OC(CC2CCCC2)Cc2c(O)c(O)ccc12 InChI=1S/C16H23NO3/c17-9-15-12-5-6-14(18)16(19)13(12)8-11(20-15)7-10-3-1-2-4-10/h5-6,10-11,15,18-19H,1-4,7-9,17H2/t11?,15-/m0/s1 LRRXEOSYJLVRAV-MHTVFEQDSA-N 50007149 1-Aminomethyl-3-cyclopentylmethyl-isochroman-5,6-diol::CHEMBL85409 D(2) dopamine receptor Rattus norvegicus 776 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007149&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320378 103920432 CHEMBL85409 ZINC26576518 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650758 NC[C@@H]1OC(CCc2ccccc2)Cc2c(O)c(O)ccc12 InChI=1S/C18H21NO3/c19-11-17-14-8-9-16(20)18(21)15(14)10-13(22-17)7-6-12-4-2-1-3-5-12/h1-5,8-9,13,17,20-21H,6-7,10-11,19H2/t13?,17-/m0/s1 KIARRRIAGXQGBT-RUINGEJQSA-N 50007128 1-Aminomethyl-3-phenethyl-isochroman-5,6-diol::CHEMBL84983 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007128&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320001 103920411 CHEMBL84983 ZINC26569603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650823 CN(CC#C)C[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCC1 InChI=1S/C20H27NO3/c1-3-11-21(2)13-19-15-9-10-17(22)20(23)16(15)12-18(24-19)14-7-5-4-6-8-14/h1,9-10,14,18-19,22-23H,4-8,11-13H2,2H3/t18?,19-/m0/s1 ORJBNDRHLGFVFW-GGYWPGCISA-N 50007142 3-Cyclohexyl-1-[(methyl-prop-2-ynyl-amino)-methyl]-isochroman-5,6-diol::CHEMBL315535 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007142&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320002 103920425 CHEMBL315535 ZINC26569605 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650824 CC[C@H]1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C12H17NO3/c1-2-7-5-9-8(11(6-13)16-7)3-4-10(14)12(9)15/h3-4,7,11,14-15H,2,5-6,13H2,1H3/t7-,11-/m0/s1 YNUUJSAVGPCWBG-CPCISQLKSA-N 50453080 CHEMBL2114209 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453080&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15696482 225145842 CHEMBL2114209 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650825 Oc1ccc2[C@H](CNCC#C)OC(Cc2c1O)C1CCCCC1 InChI=1S/C19H25NO3/c1-2-10-20-12-18-14-8-9-16(21)19(22)15(14)11-17(23-18)13-6-4-3-5-7-13/h1,8-9,13,17-18,20-22H,3-7,10-12H2/t17?,18-/m0/s1 OTQGSZPQJUEZOA-ZVAWYAOSSA-N 50007144 3-Cyclohexyl-1-prop-2-ynylaminomethyl-isochroman-5,6-diol::CHEMBL420788 D(2) dopamine receptor Rattus norvegicus 11500 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007144&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320303 103920427 CHEMBL420788 ZINC26573906 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650828 NC[C@@H]1OC(COCc2ccccc2)Cc2c(O)c(O)ccc12 InChI=1S/C18H21NO4/c19-9-17-14-6-7-16(20)18(21)15(14)8-13(23-17)11-22-10-12-4-2-1-3-5-12/h1-7,13,17,20-21H,8-11,19H2/t13?,17-/m0/s1 JAZQRIDSKRIHDH-RUINGEJQSA-N 50007153 1-Aminomethyl-3-benzyloxymethyl-isochroman-5,6-diol::CHEMBL86325 D(2) dopamine receptor Rattus norvegicus 204 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007153&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320257 103920436 CHEMBL86325 ZINC26576776 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50650829 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)C(c1ccccc1)c1ccccc1 InChI=1S/C23H23NO3/c24-14-21-17-11-12-19(25)23(26)18(17)13-20(27-21)22(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-12,20-22,25-26H,13-14,24H2/t20?,21-/m0/s1 ILWGLMLPVXFDGW-LBAQZLPGSA-N 50007141 1-Aminomethyl-3-benzhydryl-isochroman-5,6-diol::CHEMBL87172 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007141&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320256 103920424 CHEMBL87172 ZINC26576775 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013213 CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12 InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 ZPEIMTDSQAKGNT-UHFFFAOYSA-N 50001888 (chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::(chlorpromazine)[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::1N,1N-dimethyl-3-(2-chloro-10H-10-phenothiazinyl)-1-propanamine::3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine::CHEMBL71::CHLORPROMAZINE::CHLORPROMAZINE HIBENZATE::CHLORPROMAZINE HYDROCHLORIDE::CHLORPROMAZINE PHENOLPHTHALINATE::CHLORPROMAZINE TANNATE::Chlorpromazine;[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine::PROMAPAR::SONAZINE::THORAZINE::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine (chlor-promazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine( Chlorpromazine)::[3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine(clorpromazine)::chloropromazine::med.21724, Compound 15 D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001888&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search Z80 3LK0,5NUM,5NUN,5NUJ,5NUK,5G08,4MA8,7OOK,5LG3,3APX 2726 103916255 3647 CHEMBL71 DB00477 83 C06906 ZINC00044027 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013222 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CCF)cc(OC)c1OC InChI=1S/C18H27FN2O4/c1-4-21-9-5-6-13(21)11-20-18(23)15-16(22)12(7-8-19)10-14(24-2)17(15)25-3/h10,13,22H,4-9,11H2,1-3H3,(H,20,23)/t13-/m0/s1 NCDPKFAUDDDXBP-ZDUSSCGKSA-N 50008786 CHEMBL43506::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-(2-fluoro-ethyl)-2-hydroxy-5,6-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.770000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14910582 103921915 CHEMBL43506 ZINC13821891 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013226 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 8.3 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013235 CCN1CCC[C@H]1CNC(=O)c1cc(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 QAECXZXKVURFMR-LBPRGKRZSA-N 50007522 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide::5-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2,3-dimethoxybenzamide::CHEMBL289330 D(2) dopamine receptor Rattus norvegicus 0.200000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9907436 103920797 CHEMBL289330 ZINC03780178 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50013237 CCN1CCC[C@H]1CNC(=O)c1cc(I)cc(OC)c1OC InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 APNNSBJHVTUORL-LBPRGKRZSA-N 50008782 CHEMBL44237::EPIDEPRIDE::Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D(2) dopamine receptor Rattus norvegicus 0.270000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86101 103921911 CHEMBL44237 ZINC03802831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033734 CCN1CCC[C@H]1CNC(=O)c1cc(CCCF)cc(OC)c1OC InChI=1S/C19H29FN2O3/c1-4-22-10-6-8-15(22)13-21-19(23)16-11-14(7-5-9-20)12-17(24-2)18(16)25-3/h11-12,15H,4-10,13H2,1-3H3,(H,21,23)/t15-/m0/s1 CRDCKDWZBHLFAS-HNNXBMFYSA-N 50008785 CHEMBL42953::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(3-fluoro-propyl)-2,3-dimethoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(3-fluoro-propyl)-2,3-dimethoxy-benzamide (FP-epidepride) D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10043596 103921914 CHEMBL42953 ZINC05650383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647961 CCN1CCC[C@H]1CNC(=O)c1cc(CCF)cc(OC)c1OC InChI=1S/C18H27FN2O3/c1-4-21-9-5-6-14(21)12-20-18(22)15-10-13(7-8-19)11-16(23-2)17(15)24-3/h10-11,14H,4-9,12H2,1-3H3,(H,20,22)/t14-/m0/s1 ARAWZUUSXRTRLM-AWEZNQCLSA-N 50008784 CHEMBL288704::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-(2-fluoro-ethyl)-2,3-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 5.3 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008784&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14910564 103921913 CHEMBL288704 ZINC13821889 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647962 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(Cl)c1OC InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)/t12-/m0/s1 AADCDMQTJNYOSS-LBPRGKRZSA-N 50007518 (S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)methyl)-6-hydroxy-2-methoxybenzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Chloro-5-ethyl-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide (etichlopride)::3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide(Eticlopride)::3-chloro-5-ethyl-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-6-hydroxy-2-methoxybenzamide::CHEMBL8946::ETICLOPRIDE::ETICLOPRIDE,S(-)::Eticlopride;3-Chloro-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-6-hydroxy-2-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.190000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search ETQ 3PBL 57267 103920793 CHEMBL8946 966 ZINC00001395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647964 CCN1CCC[C@H]1CNC(=O)c1c(O)c(CCCF)cc(OC)c1OC InChI=1S/C19H29FN2O4/c1-4-22-10-6-8-14(22)12-21-19(24)16-17(23)13(7-5-9-20)11-15(25-2)18(16)26-3/h11,14,23H,4-10,12H2,1-3H3,(H,21,24)/t14-/m0/s1 CUVDIPGTXCBTQZ-AWEZNQCLSA-N 50008783 CHEMBL42448::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-3-(3-fluoro-propyl)-2-hydroxy-5,6-dimethoxy-benzamide D(2) dopamine receptor Rattus norvegicus 0.800000 ChEMBL 10.1021/jm00109a013 10.7270/Q2GH9GXF 1827843 Bishop, JE; Mathis, CA; Gerdes, JM; Whitney, JM; Eaton, AM; Mailman, RB University of California http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50008783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50008783&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894966 103921912 CHEMBL42448 ZINC06385020 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50668738 Oc1cccc2C3CCN(CC=C)C3CCc12 InChI=1S/C15H19NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h2-5,12,14,17H,1,6-10H2 MHHLELSXRBTNRD-UHFFFAOYSA-N 50040159 (Recemic)3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::3-Allyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL10289 D(2) dopamine receptor Rattus norvegicus 198 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040159&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266636 103972219 CHEMBL10289 ZINC13826535 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50668739 CCCN1CCC2C1CCc1c(O)cccc21 InChI=1S/C15H21NO/c1-2-9-16-10-8-12-11-4-3-5-15(17)13(11)6-7-14(12)16/h3-5,12,14,17H,2,6-10H2,1H3 SHOJVFLWKSRVPH-UHFFFAOYSA-N 50040174 (Recemic)3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::3-Propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indol-6-ol::CHEMBL10207 D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44266612 103972234 CHEMBL10207 ZINC26006261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50668744 COc1cccc2CC[C@@H]3[C@@H](CCN3CC=C)c12 InChI=1S/C16H21NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h3-6,13-14H,1,7-11H2,2H3/t13-,14-/m1/s1 VRRJFCMGNMFNOE-ZIAGYGMSSA-N 50034330 (3aR,9bS) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-3-allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aS,9bR) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 3-Allyl-9-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL26118 D(2) dopamine receptor Rattus norvegicus 270 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10105844 103942531 CHEMBL26118 ZINC03790769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50668745 CCCN1CC[C@@H]2[C@H]1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3/t13-,14-/m1/s1 HPUKPOAWHHZLIX-ZIAGYGMSSA-N 50034327 (3aR,9bS) 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-9-methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aS,9bR) 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL284585 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10332127 103942528 CHEMBL284585 ZINC13826502 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50668746 CCCN1CC[C@@H]2[C@H]1CCc1cccc(OC)c21 InChI=1S/C16H23NO/c1-3-10-17-11-9-13-14(17)8-7-12-5-4-6-15(18-2)16(12)13/h4-6,13-14H,3,7-11H2,1-2H3/t13-,14-/m1/s1 HPUKPOAWHHZLIX-ZIAGYGMSSA-N 50034327 (3aR,9bS) 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aR,9bS)-9-methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(3aS,9bR) 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::(Recemic) 9-Methoxy-3-propyl-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole::CHEMBL284585 D(2) dopamine receptor Rattus norvegicus 67 ChEMBL 10.1021/jm00062a001 10.7270/Q2TD9Z06 8496900 Chidester, CG; Lin, CH; Lahti, RA; Haadsma-Svensson, SR; Smith, MW Upjohn Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50034327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50034327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10332127 103942528 CHEMBL284585 ZINC13826502 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033622 COc1ccc(Br)c(O)c1C(=O)NC[C@H]1CCCN1Cc1ccccc1 InChI=1S/C20H23BrN2O3/c1-26-17-10-9-16(21)19(24)18(17)20(25)22-12-15-8-5-11-23(15)13-14-6-3-2-4-7-14/h2-4,6-7,9-10,15,24H,5,8,11-13H2,1H3,(H,22,25)/t15-/m1/s1 MBIMLBIDRSPVIF-OAHLLOKOSA-N 50453039 CHEMBL2096749 D(2) dopamine receptor Rattus norvegicus 0.800000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894146 225145822 CHEMBL2096749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033623 COc1ccc(Br)c(O)c1C(=O)NC[C@H]1CCCN1Cc1ccccc1 InChI=1S/C20H23BrN2O3/c1-26-17-10-9-16(21)19(24)18(17)20(25)22-12-15-8-5-11-23(15)13-14-6-3-2-4-7-14/h2-4,6-7,9-10,15,24H,5,8,11-13H2,1H3,(H,22,25)/t15-/m1/s1 MBIMLBIDRSPVIF-OAHLLOKOSA-N 50453039 CHEMBL2096749 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50453039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50453039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894146 225145822 CHEMBL2096749 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033624 COc1ccc(Br)c(O)c1C(=O)NC[C@H]1CCCN1Cc1ccc(F)cc1 InChI=1S/C20H22BrFN2O3/c1-27-17-9-8-16(21)19(25)18(17)20(26)23-11-15-3-2-10-24(15)12-13-4-6-14(22)7-5-13/h4-9,15,25H,2-3,10-12H2,1H3,(H,23,26)/t15-/m1/s1 PQAIFVHATFSBMU-OAHLLOKOSA-N 50007524 (R) 3-Bromo-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2-hydroxy-6-methoxy-benzamide::CHEMBL175082 D(2) dopamine receptor Rattus norvegicus 0.430000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007524&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894152 103920799 CHEMBL175082 ZINC13820604 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033629 COc1cc(Br)c(O)c(C(=O)NC[C@H]2CCCN2Cc2ccc(F)cc2)c1OC InChI=1S/C21H24BrFN2O4/c1-28-17-10-16(22)19(26)18(20(17)29-2)21(27)24-11-15-4-3-9-25(15)12-13-5-7-14(23)8-6-13/h5-8,10,15,26H,3-4,9,11-12H2,1-2H3,(H,24,27)/t15-/m1/s1 JPFKUHKRYXOWGK-OAHLLOKOSA-N 50007510 (R) 3-Bromo-N-[1-(4-fluoro-benzyl)-pyrrolidin-2-ylmethyl]-2-hydroxy-5,6-dimethoxy-benzamide::CHEMBL435670 D(2) dopamine receptor Rattus norvegicus 0.190000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894163 103920785 CHEMBL435670 ZINC13820617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033631 CCN1CCC[C@H]1CNC(=O)c1c(OC)c(Cl)cc(Cl)c1OC InChI=1S/C16H22Cl2N2O3/c1-4-20-7-5-6-10(20)9-19-16(21)13-14(22-2)11(17)8-12(18)15(13)23-3/h8,10H,4-7,9H2,1-3H3,(H,19,21)/t10-/m0/s1 JGQKBQNMKHVABS-JTQLQIEISA-N 50007509 3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,6-dimethoxy-benzamide::CHEMBL171921 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10689922 103920784 CHEMBL171921 ZINC02021795 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50033633 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647885 COc1cc(Br)cc(C(=O)NC[C@H]2CCCN2Cc2ccccc2)c1OC InChI=1S/C21H25BrN2O3/c1-26-19-12-16(22)11-18(20(19)27-2)21(25)23-13-17-9-6-10-24(17)14-15-7-4-3-5-8-15/h3-5,7-8,11-12,17H,6,9-10,13-14H2,1-2H3,(H,23,25)/t17-/m1/s1 VQFIJOMUUDIPOY-QGZVFWFLSA-N 50007508 (R) N-(1-Benzyl-pyrrolidin-2-ylmethyl)-5-bromo-2,3-dimethoxy-benzamide::CHEMBL176458 D(2) dopamine receptor Rattus norvegicus 0.024000 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007508&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14894156 103920783 CHEMBL176458 ZINC13820621 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647886 CCN1CCC[C@H]1CNC(=O)c1cc(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1 QAECXZXKVURFMR-LBPRGKRZSA-N 50007522 5-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2,3-dimethoxy-benzamide::5-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2,3-dimethoxybenzamide::CHEMBL289330 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9907436 103920797 CHEMBL289330 ZINC03780178 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647887 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.3 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50647888 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(OC)c1OC InChI=1S/C16H23BrN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1 WGLPSCZHULDZSS-JTQLQIEISA-N 50007517 (S)-3-bromo-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-5,6-dimethoxybenzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-5,6-dimethoxy-benzamide::CHEMBL76402 D(2) dopamine receptor Rattus norvegicus 1.4 ChEMBL 10.1021/jm00107a012 10.7270/Q2GT5NS9 1672158 Hogberg, T; Strom, P; de Paulis, T; Stensland, B; Csoregh, I; Lundin, K; Hall, H; Ogren, SO Astra Research Centre AB http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977478 103920792 CHEMBL76402 ZINC03776019 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50011149 CCC(=O)O[C@]1(CCN(CCCC(=O)c2ccc(F)cc2)CC1C)c1ccccc1 InChI=1S/C25H30FNO3/c1-3-24(29)30-25(21-8-5-4-6-9-21)15-17-27(18-19(25)2)16-7-10-23(28)20-11-13-22(26)14-12-20/h4-6,8-9,11-14,19H,3,7,10,15-18H2,1-2H3/t19?,25-/m0/s1 REXOMGWVBIKJKZ-BIAFCPFJSA-N 50007421 CHEMBL59245::Propionic acid 1-[4-(4-fluoro-phenyl)-4-oxo-butyl]-3-methyl-4-phenyl-piperidin-4-yl ester D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/jm00105a029 10.7270/Q2GM867T 1671414 Iorio, MA; Frigeni, V; Bowman, ER; Harris, LS; May, EL; Aceto, MD Istituto Superiore di Sanità http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007421 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007421&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44301589 103920696 CHEMBL59245 ZINC13860901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50612296 CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 ZEWQUBUPAILYHI-UHFFFAOYSA-N 79181 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::10-[3-(4-methylpiperazino)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride::MLS001146870::SMR000059133::TRIFLUOPERAZINE::TRIFLUOPERAZINE DIHYDROCHLORIDE::Trifluperazine::US11542290, Compound Trifluoperazine::cid_2913535::cid_5566 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/jm00153a010 10.7270/Q24X58C9 2869146 Yevich, JP; New, JS; Smith, DW; Lobeck, WG; Catt, JD; Minielli, JL; Eison, MS; Taylor, DP; Riblet, LA; Temple, DL TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79181&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search TFP 4RJD,1A29,1LIN,1WRK,1CTR,1WRL,3KO0 5566 252655893 DB00831 C07168 ZINC19418959 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50615771 Oc1ccc2c(c1)[nH]c(=O)n(CCN1CCC(CC1)C(=O)c1ccc(F)cc1)c2=O InChI=1S/C22H22FN3O4/c23-16-3-1-14(2-4-16)20(28)15-7-9-25(10-8-15)11-12-26-21(29)18-6-5-17(27)13-19(18)24-22(26)30/h1-6,13,15,27H,7-12H2,(H,24,30) KUQJDAMRVKQSPB-UHFFFAOYSA-N 50025124 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-7-hydroxy-1H-quinazoline-2,4-dione::CHEMBL46683 D(2) dopamine receptor Rattus norvegicus 417 ChEMBL 10.1021/jm00159a017 10.7270/Q2RX9B3N 3746815 Wouters, W; Janssen, CG; Van Dun, J; Thijssen, JB; Laduron, PM TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025124&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44290349 103935070 CHEMBL46683 ZINC29401908 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060200 CCCN(CCC)C1CCc2ccc3[nH]cc(C=O)c3c2C1 InChI=1S/C19H26N2O/c1-3-9-21(10-4-2)16-7-5-14-6-8-18-19(17(14)11-16)15(13-22)12-20-18/h6,8,12-13,16,20H,3-5,7,9-11H2,1-2H3 DSEPKSLFXGYPIU-UHFFFAOYSA-N 50035320 (+/-)-8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::8-Dipropylamino-6,7,8,9-tetrahydro-3H-benzo[e]indole-1-carbaldehyde::CHEMBL304426 D(2) dopamine receptor Rattus norvegicus 40 ChEMBL 10.1021/jm00067a002 10.7270/Q2MP52CR 8340910 Stjernlof, P; Gullme, M; Elebring, T; Andersson, B; Wikstrom, H; Lagerquist, S; Svensson, K; Ekman, A; Carlsson, A; Sundell, S University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 178081 103943346 CHEMBL304426 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003670 Oc1ccc2c(CCCCN3CCC(=CC3)c3ccccc3)c[nH]c2c1 InChI=1S/C23H26N2O/c26-21-9-10-22-20(17-24-23(22)16-21)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2 KELIDAHPKTUDBD-UHFFFAOYSA-N 50002169 3-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indol-6-ol::CHEMBL130502 D(2) dopamine receptor Rattus norvegicus 8 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002169&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10315634 103916475 CHEMBL130502 ZINC13728619 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003675 Fc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H25FN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-12,17,25H,3-5,13-16H2 WOQPWODQIGGKJL-UHFFFAOYSA-N 50002171 3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL64344 D(2) dopamine receptor Rattus norvegicus 90 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002171&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10452645 103916477 CHEMBL64344 ZINC13728583 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003678 Clc1ccccc1C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H25ClN2/c24-22-10-3-1-8-20(22)18-12-15-26(16-13-18)14-6-5-7-19-17-25-23-11-4-2-9-21(19)23/h1-4,8-12,17,25H,5-7,13-16H2 WWMBSJAUCLHJCQ-UHFFFAOYSA-N 50002165 3-{4-[4-(2-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL131711 D(2) dopamine receptor Rattus norvegicus 100 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002165&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10250440 103916471 CHEMBL131711 ZINC13728592 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003681 Fc1ccccc1C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 InChI=1S/C23H25FN2/c24-22-10-3-1-8-20(22)18-12-15-26(16-13-18)14-6-5-7-19-17-25-23-11-4-2-9-21(19)23/h1-4,8-12,17,25H,5-7,13-16H2 FNJKJLLZOPKWHV-UHFFFAOYSA-N 50002174 3-{4-[4-(2-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-butyl}-1H-indole::CHEMBL132270 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002174&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10247167 103916480 CHEMBL132270 ZINC13728586 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003683 Cc1[nH]c2ccccc2c1CCCCN1CCC(=CC1)c1ccccc1 InChI=1S/C24H28N2/c1-19-22(23-12-5-6-13-24(23)25-19)11-7-8-16-26-17-14-21(15-18-26)20-9-3-2-4-10-20/h2-6,9-10,12-14,25H,7-8,11,15-18H2,1H3 VPAZYSLQUPECFV-UHFFFAOYSA-N 50002162 2-Methyl-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL338849 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002162&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10407449 103916468 CHEMBL338849 ZINC13728607 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003684 C(CCN1CCC(=CC1)c1ccccc1)CCc1c[nH]c2ccccc12 InChI=1S/C24H28N2/c1-3-9-20(10-4-1)21-14-17-26(18-15-21)16-8-2-5-11-22-19-25-24-13-7-6-12-23(22)24/h1,3-4,6-7,9-10,12-14,19,25H,2,5,8,11,15-18H2 RDMGNUHCWDMCMI-UHFFFAOYSA-N 50002167 3-[5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-pentyl]-1H-indole::CHEMBL419957 D(2) dopamine receptor Rattus norvegicus 60 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002167&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10091199 103916473 CHEMBL419957 ZINC13728577 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003685 C(CCc1c[nH]c2ccccc12)CN1CCC=CC1 InChI=1S/C17H22N2/c1-5-11-19(12-6-1)13-7-4-8-15-14-18-17-10-3-2-9-16(15)17/h1-3,5,9-10,14,18H,4,6-8,11-13H2 RNGZXDOUGRHLBQ-UHFFFAOYSA-N 50002161 3-[4-(3,6-Dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::CHEMBL130605 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002161&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10446977 103916467 CHEMBL130605 ZINC13728598 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50003686 COc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1 InChI=1S/C24H28N2O/c1-27-22-10-11-24-23(17-22)21(18-25-24)9-5-6-14-26-15-12-20(13-16-26)19-7-3-2-4-8-19/h2-4,7-8,10-12,17-18,25H,5-6,9,13-16H2,1H3 OUSYTGMUXWLOBH-UHFFFAOYSA-N 50002177 5-Methoxy-3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-1H-indole::5-methoxy-3-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-1H-indole::CHEMBL130327 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm00100a006 10.7270/Q2K0736G 1359142 Bottcher, H; Barnickel, G; Hausberg, HH; Haase, AF; Seyfried, CA; Eiermann, V E. Merck Darmstadt http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50002177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50002177&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10408477 103916483 CHEMBL130327 ZINC13582350 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50649899 Fc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24FN3O2S/c24-19-8-10-20(11-9-19)26-16-14-25(15-17-26)12-3-13-27-21-6-1-4-18-5-2-7-22(23(18)21)30(27,28)29/h1-2,4-11H,3,12-17H2 VGIGHGMPMUCLIQ-UHFFFAOYSA-N 50010044 2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)::2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide(Fananserin)::CHEMBL83894::ChEMBL_131689::FANANSERIN D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60785 103922972 CHEMBL83894 5434 ZINC00597400 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50649904 Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1 InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 JUQLTPCYUFPYKE-UHFFFAOYSA-N 50001775 (ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-2,3-dihydro-1H-indolizin-5-one::(ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-8,8a-dihydro-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one (Ritanserin)::6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one(Ritanserin)::CHEMBL267777::RITANSERIN::Ritanserine::cid_5074 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1021/jm00112a025 10.7270/Q2R78FT1 1908521 Malleron, JL; Comte, MT; Gueremy, C; Peyronel, JF; Truchon, A; Blanchard, JC; Doble, A; Piot, O; Zundel, JL; Huon, C Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search E2J 6BQH 5074 103916148 64195 CHEMBL267777 97 ZINC00538314 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010517 NC[C@@H]1OC2(CCCCC2)Cc2c(O)c(O)ccc12 InChI=1S/C15H21NO3/c16-9-13-10-4-5-12(17)14(18)11(10)8-15(19-13)6-2-1-3-7-15/h4-5,13,17-18H,1-3,6-9,16H2/t13-/m0/s1 MWZPAYJAPPEPRS-ZDUSSCGKSA-N 50007145 1-Aminomethyl-isochroman-5,6-diol spirocyclohexane::CHEMBL420604 D(2) dopamine receptor Rattus norvegicus 4680 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007145&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15696487 103920428 CHEMBL420604 ZINC13823830 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010539 Oc1ccc2[C@H](CNC3CC3)OC(Cc2c1O)C1CCCCC1 InChI=1S/C19H27NO3/c21-16-9-8-14-15(19(16)22)10-17(12-4-2-1-3-5-12)23-18(14)11-20-13-6-7-13/h8-9,12-13,17-18,20-22H,1-7,10-11H2/t17?,18-/m0/s1 JMLFTEUVKWTNSN-ZVAWYAOSSA-N 50007138 3-Cyclohexyl-1-cyclopropylaminomethyl-isochroman-5,6-diol::CHEMBL86669 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007138&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320328 103920421 CHEMBL86669 ZINC26576882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010555 CCCCC1Cc2c(O)c(O)ccc2[C@H](CN)O1 InChI=1S/C14H21NO3/c1-2-3-4-9-7-11-10(13(8-15)18-9)5-6-12(16)14(11)17/h5-6,9,13,16-17H,2-4,7-8,15H2,1H3/t9?,13-/m0/s1 MMVLDBWARAYRHY-NCWAPJAISA-N 50007133 1-Aminomethyl-3-butyl-isochroman-5,6-diol::CHEMBL431220 D(2) dopamine receptor Rattus norvegicus 359 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007133&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320129 103920416 CHEMBL431220 ZINC26574347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010569 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)c1ccc(I)cc1 InChI=1S/C16H16INO3/c17-10-3-1-9(2-4-10)14-7-12-11(15(8-18)21-14)5-6-13(19)16(12)20/h1-6,14-15,19-20H,7-8,18H2/t14?,15-/m0/s1 IFTXVACPDRUAPN-LOACHALJSA-N 50007152 1-Aminomethyl-3-(4-iodo-phenyl)-isochroman-5,6-diol::CHEMBL313304 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007152&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320061 103920435 CHEMBL313304 ZINC26575639 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010570 NC[C@@H]1OC(Cc2c(O)c(O)ccc12)C1CCCCCCC1 InChI=1S/C18H27NO3/c19-11-17-13-8-9-15(20)18(21)14(13)10-16(22-17)12-6-4-2-1-3-5-7-12/h8-9,12,16-17,20-21H,1-7,10-11,19H2/t16?,17-/m0/s1 NYSMWUFTIPGKQH-DJNXLDHESA-N 50007127 1-Aminomethyl-3-cyclooctyl-isochroman-5,6-diol::CHEMBL85689 D(2) dopamine receptor Rattus norvegicus 760 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007127&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320026 103920410 CHEMBL85689 ZINC26574069 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50010575 Oc1ccc2[C@H](CNCc3ccccc3)OC(Cc2c1O)C1CCCCC1 InChI=1S/C23H29NO3/c25-20-12-11-18-19(23(20)26)13-21(17-9-5-2-6-10-17)27-22(18)15-24-14-16-7-3-1-4-8-16/h1,3-4,7-8,11-12,17,21-22,24-26H,2,5-6,9-10,13-15H2/t21?,22-/m0/s1 CDEXVBIHAFJWIQ-KEKNWZKVSA-N 50007132 1-(Benzylamino-methyl)-3-cyclohexyl-isochroman-5,6-diol::CHEMBL315516 D(2) dopamine receptor Rattus norvegicus 2450 ChEMBL 10.1021/jm00112a034 10.7270/Q2HM57DN 1652023 DeNinno, MP; Schoenleber, R; Perner, RJ; Lijewski, L; Asin, KE; Britton, DR; MacKenzie, R; Kebabian, JW Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007132&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44320304 103920415 CHEMBL315516 ZINC26575010 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50668317 COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CCC1C2 InChI=1S/C15H20ClN3O2/c1-21-14-7-12(17)11(16)6-10(14)15(20)18-13-3-5-19-4-2-9(13)8-19/h6-7,9,13H,2-5,8,17H2,1H3,(H,18,20) DTTGUKXBOVDIES-UHFFFAOYSA-N 50212465 Renzapride D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00086a019 10.7270/Q2CC11B3 1573641 Flynn, DL; Zabrowski, DL; Becker, DP; Nosal, R; Villamil, CI; Gullikson, GW; Moummi, C; Yang, DC Searle Research and Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50212465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50212465&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44374544 376070457 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50612155 COc1ccc(cc1OC)[C@@H](O)[C@@H](C)N1CCN(CC1)c1cccccc1=O InChI=1S/C22H28N2O4/c1-16(22(26)17-9-10-20(27-2)21(15-17)28-3)23-11-13-24(14-12-23)18-7-5-4-6-8-19(18)25/h4-10,15-16,22,26H,11-14H2,1-3H3/t16-,22+/m1/s1 VHWWMFMKKRWURA-ZHRRBRCNSA-N 50226137 CHEMBL3349048 D(2) dopamine receptor Rattus norvegicus 8550 ChEMBL 10.1021/jm00152a004 10.7270/Q2N29VZH 3950903 Bagli, J; Bogri, T; Voith, K; Lee, D TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226137&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118718130 378166653 CHEMBL3349048 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032506 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Rattus norvegicus 184 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032507 CCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C11H17N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h4,8H,2-3,5-7H2,1H3,(H2,12,13) VJPANQWIZQHGMJ-UHFFFAOYSA-N 50007573 4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazol-2-ylamine::CHEMBL93428 D(2) dopamine receptor Rattus norvegicus 596 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 194775 103920843 CHEMBL93428 ZINC13209017 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032510 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Rattus norvegicus 590 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032512 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032513 CCCCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C13H21N3S/c1-2-3-4-7-16-8-5-6-11(9-16)12-10-17-13(14)15-12/h6,10H,2-5,7-9H2,1H3,(H2,14,15) ZQQLUAMRCWINDM-UHFFFAOYSA-N 50367943 CHEMBL1202201 D(2) dopamine receptor Rattus norvegicus 1850 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367943&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823132 160847045 CHEMBL1202201 ZINC26935617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032514 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Rattus norvegicus 930 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032516 CCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C10H15N3S/c1-2-13-5-3-4-8(6-13)9-7-14-10(11)12-9/h4,7H,2-3,5-6H2,1H3,(H2,11,12) CSGZCYPSSIETMO-UHFFFAOYSA-N 50010573 4-(1-Ethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazol-2-ylamine::CHEMBL106028 D(2) dopamine receptor Rattus norvegicus 945 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010573&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823129 103923349 CHEMBL106028 ZINC26845072 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50032517 CCCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C12H19N3S/c1-2-3-6-15-7-4-5-10(8-15)11-9-16-12(13)14-11/h5,9H,2-4,6-8H2,1H3,(H2,13,14) DSEWXIWVTCTEJG-UHFFFAOYSA-N 50367940 CHEMBL1203007 D(2) dopamine receptor Rattus norvegicus 3985 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367940&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823130 160847042 CHEMBL1203007 ZINC26843782 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50627182 Nc1nc(cs1)C1=CCCN(CC=C)C1 InChI=1S/C11H15N3S/c1-2-5-14-6-3-4-9(7-14)10-8-15-11(12)13-10/h2,4,8H,1,3,5-7H2,(H2,12,13) JMEQXIANNKFBTB-UHFFFAOYSA-N 50010580 4-(1-Allyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazol-2-ylamine::CHEMBL106257 D(2) dopamine receptor Rattus norvegicus 440 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010580&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 194776 103923356 CHEMBL106257 ZINC13208878 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50627183 CCCN1CCC=C(C1)c1csc(NC)n1 InChI=1S/C12H19N3S/c1-3-6-15-7-4-5-10(8-15)11-9-16-12(13-2)14-11/h5,9H,3-4,6-8H2,1-2H3,(H,13,14) PYYWPVKGPXCJDC-UHFFFAOYSA-N 50010571 CHEMBL108682::Methyl-[4-(1-propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiazol-2-yl]-amine D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010571 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010571&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823145 103923347 CHEMBL108682 ZINC26938695 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50627184 Nc1nc(cs1)C1=CCCN(CCc2ccccc2)C1 InChI=1S/C16H19N3S/c17-16-18-15(12-20-16)14-7-4-9-19(11-14)10-8-13-5-2-1-3-6-13/h1-3,5-7,12H,4,8-11H2,(H2,17,18) VUQQHXCBPFASSP-UHFFFAOYSA-N 50367946 CHEMBL1203001 D(2) dopamine receptor Rattus norvegicus 1080 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823140 160847048 CHEMBL1203001 ZINC26847412 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50627323 CCCCCCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C15H25N3S/c1-2-3-4-5-6-9-18-10-7-8-13(11-18)14-12-19-15(16)17-14/h8,12H,2-7,9-11H2,1H3,(H2,16,17) PSODDODKEIFPDE-UHFFFAOYSA-N 50367944 CHEMBL1203004 D(2) dopamine receptor Rattus norvegicus 5132 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367944&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823136 160847046 CHEMBL1203004 ZINC36093061 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50627324 CCCCCCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C14H23N3S/c1-2-3-4-5-8-17-9-6-7-12(10-17)13-11-18-14(15)16-13/h7,11H,2-6,8-10H2,1H3,(H2,15,16) YIMBWRIQKZKNDQ-UHFFFAOYSA-N 50367941 CHEMBL1203003 D(2) dopamine receptor Rattus norvegicus 5328 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367941&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823134 160847043 CHEMBL1203003 ZINC26846335 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50627325 CC(C)CCN1CCC=C(C1)c1csc(N)n1 InChI=1S/C13H21N3S/c1-10(2)5-7-16-6-3-4-11(8-16)12-9-17-13(14)15-12/h4,9-10H,3,5-8H2,1-2H3,(H2,14,15) SBAYDHJDGKVZBW-UHFFFAOYSA-N 50367939 CHEMBL1203002 D(2) dopamine receptor Rattus norvegicus 10000 ChEMBL 10.1021/jm00163a051 10.7270/Q28S4QHZ 1967314 Jaen, JC; Wise, LD; Caprathe, BW; Tecle, H; Bergmeier, S; Humblet, CC; Heffner, TG; Meltzer, LT; Pugsley, TA Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367939&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13823138 160847041 CHEMBL1203002 ZINC26845861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50034447 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50034448 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50034449 COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 InChI=1S/C20H24ClN3O2/c1-26-19-12-18(22)17(21)11-16(19)20(25)23-15-7-9-24(10-8-15)13-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10,13,22H2,1H3,(H,23,25) BVPWJMCABCPUQY-UHFFFAOYSA-N 50132693 4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide::4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide(Clebopride)::4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide::CHEMBL325109::Clebopride D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132693&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2780 104023670 CHEMBL325109 ZINC00608261 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056946 CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 BGRJTUBHPOOWDU-NSHDSACASA-N 81774 CAS_15676-16-1::SULPIRIDE,(+)::Sulpiride-S::Sulpiride-l D(2) dopamine receptor Rattus norvegicus 233 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81774 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81774&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 688272 131342348 64119 958 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056949 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 104 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50654466 CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19) TTWJBBZEZQICBI-UHFFFAOYSA-N 48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659 D(2) dopamine receptor Rattus norvegicus 104 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48320 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48320&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4168 252628615 DB01233 C07868 ZINC01530716 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50654467 CNc1cc(OC)c(cc1Cl)C(=O)N[C@H]1CCN(Cc2ccccc2)[C@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m0/s1 KRVOJOCLBAAKSJ-KSSFIOAISA-N 50005120 CHEMBL274491::N-((2S,3S)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::N-(1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide::Nemonapride::YM-09151-2 D(2) dopamine receptor Rattus norvegicus 0.490000 ChEMBL 10.1021/jm00091a002 10.7270/Q2R2120B 1535660 Pettersson, I; Liljefors, T University of Lund http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9952220 103918666 64218 CHEMBL274491 ZINC00586739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50618978 O=C1NCN(c2ccccc2)C11CCN(CC2COc3ccccc3O2)CC1 InChI=1S/C22H25N3O3/c26-21-22(25(16-23-21)17-6-2-1-3-7-17)10-12-24(13-11-22)14-18-15-27-19-8-4-5-9-20(19)28-18/h1-9,18H,10-16H2,(H,23,26) JVGBTTIJPBFLTE-UHFFFAOYSA-N 50020192 8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL300555::Spiroxatrine D(2) dopamine receptor Rattus norvegicus 1.5 ChEMBL 10.1021/jm00118a017 10.7270/Q2NV9H7W 2902227 Nikam, SS; Martin, AR; Nelson, DL University of Arizona http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020192&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5268 103931109 CHEMBL300555 53 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031345 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031347 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 1700 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50031348 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 14 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50618993 CCN1CCC[C@H]1CNC(=O)c1cc(I)ccc1OC InChI=1S/C15H21IN2O2/c1-3-18-8-4-5-12(18)10-17-15(19)13-9-11(16)6-7-14(13)20-2/h6-7,9,12H,3-5,8,10H2,1-2H3,(H,17,19)/t12-/m0/s1 JHMTYLJMPBFCTD-LBPRGKRZSA-N 50012967 CHEMBL49897::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide (iodopride)::N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide(iodopride) D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9977544 103925215 CHEMBL49897 ZINC06385022 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50618994 CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) BGRJTUBHPOOWDU-UHFFFAOYSA-N 11638 CHEMBL26::Compound 7::N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide::SULPIRIDE,(+)::SULPIRIDE,(-)::Sulpiride::Sulpiride, SLP::Sulpiride-R::US10172837, Sulpiride D(2) dopamine receptor Rattus norvegicus 33 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11638&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5355 46512161 32168 CHEMBL26 DB00391 5501 ZINC00057008 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50618995 CCN1CCC[C@@H]1CNC(=O)c1cc(I)ccc1OC InChI=1S/C15H21IN2O2/c1-3-18-8-4-5-12(18)10-17-15(19)13-9-11(16)6-7-14(13)20-2/h6-7,9,12H,3-5,8,10H2,1-2H3,(H,17,19)/t12-/m1/s1 JHMTYLJMPBFCTD-GFCCVEGCSA-N 50452484 CHEMBL2115023 D(2) dopamine receptor Rattus norvegicus 113 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452484&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3082754 225145692 CHEMBL2115023 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50618996 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 600 ChEMBL 10.1021/jm00118a031 10.7270/Q2FX7B0R 3172140 de Paulis, T; Janowsky, A; Kessler, RM; Clanton, JA; Smith, HE Vanderbilt University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50609431 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)ccc1OC InChI=1S/C15H21BrN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1 PWEZBNRZEHPIIQ-JTQLQIEISA-N 50007534 3-Bromo-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3-Bromo-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::A 35043::CHEMBL283099 D(2) dopamine receptor Rattus norvegicus 21.0 ChEMBL 10.1021/jm00147a025 10.7270/Q2QZ2BHD 4040977 de Paulis, T; Kumar, Y; Johansson, L; Ramsby, S; Florvall, L; Hall, H; Angeby-Moller, K; Ogren, SO TBA http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 94688 103920809 CHEMBL283099 ZINC05851780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015641 CCCN1CCO[C@H]2[C@H]1COc1ccc(O)cc21 InChI=1S/C14H19NO3/c1-2-5-15-6-7-17-14-11-8-10(16)3-4-13(11)18-9-12(14)15/h3-4,8,12,14,16H,2,5-7,9H2,1H3/t12-,14-/m1/s1 YOILXOMTHPUMRG-TZMCWYRMSA-N 50010586 (+)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(4aR,10aR)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(Racemic)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(trans)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol (PD 128907)::1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::CHEMBL70565::PD 128,907 D(2) dopamine receptor Rattus norvegicus 409 ChEMBL 10.1021/jm00163a068 10.7270/Q2BK1B94 1967318 DeWald, HA; Heffner, TG; Jaen, JC; Lustgarten, DM; McPhail, AT; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6O 7CMV 5311346 103923362 CHEMBL70565 ZINC25726114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015643 CCCN1CCO[C@H]2[C@H]1COc1ccc(O)cc21 InChI=1S/C14H19NO3/c1-2-5-15-6-7-17-14-11-8-10(16)3-4-13(11)18-9-12(14)15/h3-4,8,12,14,16H,2,5-7,9H2,1H3/t12-,14-/m1/s1 YOILXOMTHPUMRG-TZMCWYRMSA-N 50010586 (+)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(-)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(4aR,10aR)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(Racemic)-1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::(trans)1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol (PD 128907)::1-Propyl-2,3,10,10a-tetrahydro-1H,4aH-4,9-dioxa-1-aza-phenanthren-6-ol::CHEMBL70565::PD 128,907 D(2) dopamine receptor Rattus norvegicus 123 ChEMBL 10.1021/jm00163a068 10.7270/Q2BK1B94 1967318 DeWald, HA; Heffner, TG; Jaen, JC; Lustgarten, DM; McPhail, AT; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010586&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6O 7CMV 5311346 103923362 CHEMBL70565 ZINC25726114 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015644 CCCN(CCC)C1COc2ccc(O)cc2C1 InChI=1S/C15H23NO2/c1-3-7-16(8-4-2)13-9-12-10-14(17)5-6-15(12)18-11-13/h5-6,10,13,17H,3-4,7-9,11H2,1-2H3 COYBCQFIVNQGKW-UHFFFAOYSA-N 50010587 3-Dipropylamino-chroman-6-ol::CHEMBL69414 D(2) dopamine receptor Rattus norvegicus 800 ChEMBL 10.1021/jm00163a068 10.7270/Q2BK1B94 1967318 DeWald, HA; Heffner, TG; Jaen, JC; Lustgarten, DM; McPhail, AT; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010587&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86146 103923363 CHEMBL69414 ZINC05647677 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50015645 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1021/jm00163a068 10.7270/Q2BK1B94 1967318 DeWald, HA; Heffner, TG; Jaen, JC; Lustgarten, DM; McPhail, AT; Meltzer, LT; Pugsley, TA; Wise, LD Warner-Lambert Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50673865 Cc1nccn1C[C@H]1CCc2c(C1=O)c1cccc3CCCn2c13 InChI=1S/C20H21N3O/c1-13-21-9-11-22(13)12-15-7-8-17-18(20(15)24)16-6-2-4-14-5-3-10-23(17)19(14)16/h2,4,6,9,11,15H,3,5,7-8,10,12H2,1H3/t15-/m1/s1 NCNFDKWULDWJDS-OAHLLOKOSA-N 50231569 Cilansetron::KC-9946 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1021/jm00075a026 10.7270/Q2NS0SZH 8246239 van Wijngaarden, I; Hamminga, D; van Hes, R; Standaar, PJ; Tipker, J; Tulp, MT; Mol, F; Olivier, B; de Jonge, A Solvay Duphar B.V. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231569 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231569&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6918107 381616955 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50672061 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=S)CC2)c2ccc(F)cc12 InChI=1S/C25H30F2N4S/c26-19-4-2-18(3-5-19)22-17-24(21-7-6-20(27)16-23(21)22)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) PBFXTDGYIRQFSK-UHFFFAOYSA-N 50368656 CHEMBL1204307::CHEMBL1744111 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368656&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037269 160847758 CHEMBL1744111CHEMBL1204307 ZINC22940839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50672062 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=S)CC2)c2ccc(F)cc12 InChI=1S/C25H30F2N4S/c26-19-4-2-18(3-5-19)22-17-24(21-7-6-20(27)16-23(21)22)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) PBFXTDGYIRQFSK-UHFFFAOYSA-N 50368656 CHEMBL1204307::CHEMBL1744111 D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368656&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037269 160847758 CHEMBL1744111CHEMBL1204307 ZINC22940839 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50672063 OCCN1CCN(CC1)C1CC(c2cc(F)ccc12)c1ccc(F)cc1 InChI=1S/C21H24F2N2O/c22-16-3-1-15(2-4-16)19-14-21(18-6-5-17(23)13-20(18)19)25-9-7-24(8-10-25)11-12-26/h1-6,13,19,21,26H,7-12,14H2 XISRGFHXAPVIRZ-UHFFFAOYSA-N 50045614 2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL1204306::CHEMBL320684 D(2) dopamine receptor Rattus norvegicus 330 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154792 103976490 CHEMBL320684CHEMBL1204306 ZINC22940744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50672064 OCCN1CCN(CC1)C1CC(c2cc(F)ccc12)c1ccc(F)cc1 InChI=1S/C21H24F2N2O/c22-16-3-1-15(2-4-16)19-14-21(18-6-5-17(23)13-20(18)19)25-9-7-24(8-10-25)11-12-26/h1-6,13,19,21,26H,7-12,14H2 XISRGFHXAPVIRZ-UHFFFAOYSA-N 50045614 2-{4-[5-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethanol::CHEMBL1204306::CHEMBL320684 D(2) dopamine receptor Rattus norvegicus 330 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 13154792 103976490 CHEMBL320684CHEMBL1204306 ZINC22940744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060430 NC1CC(c2ccccc2)c2cc(O)c(O)cc2C1 InChI=1S/C16H17NO2/c17-12-6-11-7-15(18)16(19)9-14(11)13(8-12)10-4-2-1-3-5-10/h1-5,7,9,12-13,18-19H,6,8,17H2 SSUNCBAILFPJRJ-UHFFFAOYSA-N 50040280 CHEMBL538263::cis-7-Amino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide::trans-7-Amino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide D(2) dopamine receptor Rattus norvegicus >30000 ChEMBL 10.1021/jm00069a013 10.7270/Q2C53MGM 8102651 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040280&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15657205 103972340 CHEMBL538263 ZINC26572113 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50671218 CN(C)C1CC(c2ccccc2)c2cc(O)c(O)cc2C1 InChI=1S/C18H21NO2/c1-19(2)14-8-13-9-17(20)18(21)11-16(13)15(10-14)12-6-4-3-5-7-12/h3-7,9,11,14-15,20-21H,8,10H2,1-2H3 IFDQCFBQHUVXHV-UHFFFAOYSA-N 50040281 CHEMBL105645::CHEMBL543134::cis-7-Dimethylamino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide::trans-7-Dimethylamino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide D(2) dopamine receptor Rattus norvegicus >5000 ChEMBL 10.1021/jm00069a013 10.7270/Q2C53MGM 8102651 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15657199 103972341 CHEMBL543134CHEMBL105645 ZINC26571926 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50056599 Fc1ccc2c(CCCCN3C4CCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 InChI=1S/C24H23F2N3O/c25-14-5-8-19-18(11-14)24-21(27-19)13-16-6-9-22(24)29(16)10-2-1-3-20-17-7-4-15(26)12-23(17)30-28-20/h4-5,7-8,11-12,16,22,27H,1-3,6,9-10,13H2 RKKLLFDATFBVDR-UHFFFAOYSA-N 50036649 (7R,10S)-1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::(7S,10R)-1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]butane::CHEMBL284163 D(2) dopamine receptor Rattus norvegicus 0.710000 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646191 103944290 CHEMBL284163 ZINC13827354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50673285 Fc1ccc(cc1)C(=O)CCCCN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C24H25FN2O/c25-17-10-8-16(9-11-17)23(28)7-3-4-14-27-18-12-13-22(27)24-19-5-1-2-6-20(19)26-21(24)15-18/h1-2,5-6,8-11,18,22,26H,3-4,7,12-15H2 AFVUFWHJUYVTQW-UHFFFAOYSA-N 50036647 (7R,10S)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::(7S,10R)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::CHEMBL285712 D(2) dopamine receptor Rattus norvegicus 4.43 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9842628 103944288 CHEMBL285712 ZINC03801105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50673290 Fc1ccc(cc1)C(=O)CCCCN1C2CCC1c1c(C2)[nH]c2ccccc12 InChI=1S/C24H25FN2O/c25-17-10-8-16(9-11-17)23(28)7-3-4-14-27-18-12-13-22(27)24-19-5-1-2-6-20(19)26-21(24)15-18/h1-2,5-6,8-11,18,22,26H,3-4,7,12-15H2 AFVUFWHJUYVTQW-UHFFFAOYSA-N 50036647 (7R,10S)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::(7S,10R)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::5-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::CHEMBL285712 D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036647&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9842628 103944288 CHEMBL285712 ZINC03801105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50673313 Fc1ccc(cc1)C(=O)CCCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 InChI=1S/C24H24F2N2O/c25-16-6-4-15(5-7-16)23(29)3-1-2-12-28-18-9-11-22(28)24-19-13-17(26)8-10-20(19)27-21(24)14-18/h4-8,10,13,18,22,27H,1-3,9,11-12,14H2 VFPYMAAKRGRXBH-UHFFFAOYSA-N 50036650 (7R,10S)-5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::(7S,10R)-5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::CHEMBL291254 D(2) dopamine receptor Rattus norvegicus 755 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036650&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646166 103944291 CHEMBL291254 ZINC13827343 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50673321 Fc1ccc(cc1)C(=O)CCCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 InChI=1S/C24H24F2N2O/c25-16-6-4-15(5-7-16)23(29)3-1-2-12-28-18-9-11-22(28)24-19-13-17(26)8-10-20(19)27-21(24)14-18/h4-8,10,13,18,22,27H,1-3,9,11-12,14H2 VFPYMAAKRGRXBH-UHFFFAOYSA-N 50036650 (7R,10S)-5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::(7S,10R)-5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]-1-(4-fluorophenyl)-1-pentanone::CHEMBL291254 D(2) dopamine receptor Rattus norvegicus 755 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036650&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646166 103944291 CHEMBL291254 ZINC13827343 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50673345 Fc1ccc2c(CCCN3C4CCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 InChI=1S/C23H21F2N3O/c24-13-4-7-18-17(10-13)23-20(26-18)12-15-5-8-21(23)28(15)9-1-2-19-16-6-3-14(25)11-22(16)29-27-19/h3-4,6-7,10-11,15,21,26H,1-2,5,8-9,12H2 FUWBTIWZNWXCRS-UHFFFAOYSA-N 50036651 (7R,10S)-1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::(7S,10R)-1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::CHEMBL284172 D(2) dopamine receptor Rattus norvegicus 308 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646187 103944292 CHEMBL284172 ZINC13827352 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50673347 Fc1ccc2c(CCCN3C4CCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 InChI=1S/C23H21F2N3O/c24-13-4-7-18-17(10-13)23-20(26-18)12-15-5-8-21(23)28(15)9-1-2-19-16-6-3-14(25)11-22(16)29-27-19/h3-4,6-7,10-11,15,21,26H,1-2,5,8-9,12H2 FUWBTIWZNWXCRS-UHFFFAOYSA-N 50036651 (7R,10S)-1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::(7S,10R)-1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadeca-2(10),3,5,7-tetraen-15-yl]propane::CHEMBL284172 D(2) dopamine receptor Rattus norvegicus 308 ChEMBL 10.1021/jm00073a005 10.7270/Q2RF5T2N 7901415 Mewshaw, RE; Abreu, ME; Silverman, LS; Mathew, RM; Tiffany, CW; Bailey, MA; Karbon, EW; Ferkany, JW; Kaiser, C Scios Nova Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50036651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50036651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15646187 103944292 CHEMBL284172 ZINC13827352 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061102 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061105 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Rattus norvegicus 700 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061112 CCCN1CCCC(C1)c1cccc(c1)C#N InChI=1S/C15H20N2/c1-2-8-17-9-4-7-15(12-17)14-6-3-5-13(10-14)11-16/h3,5-6,10,15H,2,4,7-9,12H2,1H3 GQRIAOUUYRIMLH-UHFFFAOYSA-N 50041960 (+)-3-(1-Propyl-piperidin-3-yl)-benzonitrile::(-)-3-(1-Propyl-piperidin-3-yl)-benzonitrile::3-(1-Propyl-piperidin-3-yl)-benzonitrile::CHEMBL107492 D(2) dopamine receptor Rattus norvegicus 12600 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5119 103973639 CHEMBL107492 ZINC03785159 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061120 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.200000 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061154 CCCN1CCC[C@H](C1)c1cccc(OS(=O)(=O)C(F)(F)F)c1 InChI=1S/C15H20F3NO3S/c1-2-8-19-9-4-6-13(11-19)12-5-3-7-14(10-12)22-23(20,21)15(16,17)18/h3,5,7,10,13H,2,4,6,8-9,11H2,1H3/t13-/m1/s1 VUEGBGWRCATKQZ-CYBMUJFWSA-N 50039760 (-)-Trifluoro-methanesulfonic acid 3-(1-propyl-piperidin-3-yl)-phenyl ester::CHEMBL90359::Trifluoro-methanesulfonic acid 3-((S)-1-propyl-piperidin-3-yl)-phenyl ester D(2) dopamine receptor Rattus norvegicus 410 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50039760 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50039760&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654433 103946955 CHEMBL90359 ZINC36187784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50066859 CCCN1CCC[C@@H](C1)c1cccc(OS(=O)(=O)C(F)(F)F)c1 InChI=1S/C15H20F3NO3S/c1-2-8-19-9-4-6-13(11-19)12-5-3-7-14(10-12)22-23(20,21)15(16,17)18/h3,5,7,10,13H,2,4,6,8-9,11H2,1H3/t13-/m0/s1 VUEGBGWRCATKQZ-ZDUSSCGKSA-N 50041962 (+)-Trifluoro-methanesulfonic acid 3-(1-propyl-piperidin-3-yl)-phenyl ester::CHEMBL110821 D(2) dopamine receptor Rattus norvegicus 5600 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041962&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15654434 103973641 CHEMBL110821 ZINC36093062 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50066865 CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C InChI=1S/C18H29NO/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4/h7-9,14,17H,5-6,10-13H2,1-4H3/t14-,17+/m0/s1 BTOJYCTUJJHANF-WMLDXEAASA-N 50041961 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-dipropyl-amine::CHEMBL278751::UH-232 D(2) dopamine receptor Rattus norvegicus 70 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041961&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6604756 103973640 CHEMBL278751 ZINC03995702 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50066887 CCCN1CCCC(C1)c1cccc(O)c1 InChI=1S/C14H21NO/c1-2-8-15-9-4-6-13(11-15)12-5-3-7-14(16)10-12/h3,5,7,10,13,16H,2,4,6,8-9,11H2,1H3 HTSNFXAICLXZMA-UHFFFAOYSA-N 81924 (R)-3-(1-Propyl-piperidin-3-yl)-phenol::3PPP(+/-)::CAS_85976-54-1::CHEMBL276500::NSC_202477::PPP, R(+)-3::PPP, S(-)-3 D(2) dopamine receptor Rattus norvegicus 70.0 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81924&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 55445 131342498 CHEMBL276500 ZINC00402947 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50066888 CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C InChI=1S/C15H23NO/c1-4-10-16-14-9-8-13-12(11(14)2)6-5-7-15(13)17-3/h5-7,11,14,16H,4,8-10H2,1-3H3/t11-,14+/m0/s1 YGHLYBIUVOLKCV-SMDDNHRTSA-N 50041959 ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine::AJ76(+)::CHEMBL27441 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041959&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122334 103973638 64117 CHEMBL27441 970 ZINC03995669 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50066893 CCCN1CCCC(C1)c1cccc(c1)C#N InChI=1S/C15H20N2/c1-2-8-17-9-4-7-15(12-17)14-6-3-5-13(10-14)11-16/h3,5-6,10,15H,2,4,7-9,12H2,1H3 GQRIAOUUYRIMLH-UHFFFAOYSA-N 50041960 (+)-3-(1-Propyl-piperidin-3-yl)-benzonitrile::(-)-3-(1-Propyl-piperidin-3-yl)-benzonitrile::3-(1-Propyl-piperidin-3-yl)-benzonitrile::CHEMBL107492 D(2) dopamine receptor Rattus norvegicus 4900 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5119 103973639 CHEMBL107492 ZINC03785159 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50066899 CCCN1CCCC(C1)c1cccc(c1)C#N InChI=1S/C15H20N2/c1-2-8-17-9-4-7-15(12-17)14-6-3-5-13(10-14)11-16/h3,5-6,10,15H,2,4,7-9,12H2,1H3 GQRIAOUUYRIMLH-UHFFFAOYSA-N 50041960 (+)-3-(1-Propyl-piperidin-3-yl)-benzonitrile::(-)-3-(1-Propyl-piperidin-3-yl)-benzonitrile::3-(1-Propyl-piperidin-3-yl)-benzonitrile::CHEMBL107492 D(2) dopamine receptor Rattus norvegicus 4900 ChEMBL 10.1021/jm00073a021 10.7270/Q2VH5MWJ 8230107 Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikstrom, H University of Göteborg http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50041960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50041960&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5119 103973639 CHEMBL107492 ZINC03785159 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50061399 CCCN(CCC)C1CCc2cc(OS(=O)(=O)C(F)(F)F)ccc2C1 InChI=1S/C17H24F3NO3S/c1-3-9-21(10-4-2)15-7-5-14-12-16(8-6-13(14)11-15)24-25(22,23)17(18,19)20/h6,8,12,15H,3-5,7,9-11H2,1-2H3 BGPASGZLQNQAAZ-UHFFFAOYSA-N 50042339 CHEMBL442203::Trifluoro-methanesulfonic acid 6-dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-yl ester D(2) dopamine receptor Rattus norvegicus 1570 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14977564 103973945 CHEMBL442203 ZINC36093064 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50673618 CCCN(CCC)C1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1 InChI=1S/C17H24F3NO3S/c1-3-9-21(10-4-2)15-7-5-13-6-8-16(12-14(13)11-15)24-25(22,23)17(18,19)20/h6,8,12,15H,3-5,7,9-11H2,1-2H3 JVSIKYVCSMXDOZ-UHFFFAOYSA-N 50042340 CHEMBL114433::Trifluoro-methanesulfonic acid 7-dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-yl ester D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14977565 103973946 CHEMBL114433 ZINC36187802 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50673619 CCCN(CCC)C1CCc2c(C1)cccc2OS(=O)(=O)C(F)(F)F InChI=1S/C17H24F3NO3S/c1-3-10-21(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)24-25(22,23)17(18,19)20/h5-7,14H,3-4,8-12H2,1-2H3 GQWGKLIYDKGPRT-UHFFFAOYSA-N 50042341 CHEMBL324750::Trifluoro-methanesulfonic acid 6-dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-yl ester D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/jm00074a022 10.7270/Q2X067NP 8230131 Sonesson, C; Boije, M; Svensson, K; Ekman, A; Carlsson, A; Romero, AG; Martin, IJ; Duncan, JN; King, LJ; Wikstrom, H Medicinaregatan http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14977563 103973947 CHEMBL324750 ZINC36187800 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060685 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=O)CC2)c2ccc(F)cc12 InChI=1S/C25H30F2N4O/c26-19-4-2-18(3-5-19)22-17-24(21-7-6-20(27)16-23(21)22)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) PZHUDBDNTWZLRQ-UHFFFAOYSA-N 50368675 CHEMBL1744113 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368675&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037273 160847777 CHEMBL1744113 ZINC26660913 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060706 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=S)CC2)c2ccc(Cl)cc12 InChI=1S/C25H30ClFN4S/c26-19-4-7-21-23(16-19)22(18-2-5-20(27)6-3-18)17-24(21)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) ADJUKJVEVGOWPC-UHFFFAOYSA-N 50368668 CHEMBL1788128 D(2) dopamine receptor Rattus norvegicus 490 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368668&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037250 160847770 CHEMBL1788128 ZINC22940833 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50060708 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=S)CC2)c2ccc(Cl)cc12 InChI=1S/C25H30ClFN4S/c26-19-4-7-21-23(16-19)22(18-2-5-20(27)6-3-18)17-24(21)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) ADJUKJVEVGOWPC-UHFFFAOYSA-N 50368668 CHEMBL1788128 D(2) dopamine receptor Rattus norvegicus 490 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368668&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037250 160847770 CHEMBL1788128 ZINC22940833 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50671820 Fc1ccc(cc1)C1CC(N2CCN(CCN3CCCNC3=O)CC2)c2ccc(Cl)cc12 InChI=1S/C25H30ClFN4O/c26-19-4-7-21-23(16-19)22(18-2-5-20(27)6-3-18)17-24(21)30-13-10-29(11-14-30)12-15-31-9-1-8-28-25(31)32/h2-7,16,22,24H,1,8-15,17H2,(H,28,32) HSNXEFAUYFXJAP-UHFFFAOYSA-N 50368657 CHEMBL1744114 D(2) dopamine receptor Rattus norvegicus 1700 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368657&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 19037281 160847759 CHEMBL1744114 ZINC26661609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50671849 Cl.Cl.OCCN1CCN(CC1)C1CC(c2cc(Cl)ccc12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2O.2ClH/c22-16-3-6-18-20(13-16)19(15-1-4-17(23)5-2-15)14-21(18)25-9-7-24(8-10-25)11-12-26;;/h1-6,13,19,21,26H,7-12,14H2;2*1H DXUBHXOFLIXZOM-UHFFFAOYSA-N 50045636 3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-oxazolidin-2-one dihydrochloride::CHEMBL2111567 D(2) dopamine receptor Rattus norvegicus 6300 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71457959 103976512 CHEMBL2111567 ZINC26669872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50671850 Cl.Cl.OCCN1CCN(CC1)C1CC(c2cc(Cl)ccc12)c1ccc(F)cc1 InChI=1S/C21H24ClFN2O.2ClH/c22-16-3-6-18-20(13-16)19(15-1-4-17(23)5-2-15)14-21(18)25-9-7-24(8-10-25)11-12-26;;/h1-6,13,19,21,26H,7-12,14H2;2*1H DXUBHXOFLIXZOM-UHFFFAOYSA-N 50045636 3-(2-{4-[5-Chloro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-oxazolidin-2-one dihydrochloride::CHEMBL2111567 D(2) dopamine receptor Rattus norvegicus 370 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71457959 103976512 CHEMBL2111567 ZINC26669872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50671921 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2ccc(F)cc2)C1=O InChI=1S/C27H34ClFN4O/c1-19(2)33-16-15-32(27(33)34)14-11-30-9-12-31(13-10-30)26-18-24(20-3-6-22(29)7-4-20)25-17-21(28)5-8-23(25)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3 SDFCYOFNWWEZEI-UHFFFAOYSA-N 50368661 CHEMBL1744121 D(2) dopamine receptor Rattus norvegicus 1300 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368661&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9913230 160847763 CHEMBL1744121 ZINC22940772 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50671922 CC(C)N1CCN(CCN2CCN(CC2)C2CC(c3cc(Cl)ccc23)c2ccc(F)cc2)C1=O InChI=1S/C27H34ClFN4O/c1-19(2)33-16-15-32(27(33)34)14-11-30-9-12-31(13-10-30)26-18-24(20-3-6-22(29)7-4-20)25-17-21(28)5-8-23(25)26/h3-8,17,19,24,26H,9-16,18H2,1-2H3 SDFCYOFNWWEZEI-UHFFFAOYSA-N 50368661 CHEMBL1744121 D(2) dopamine receptor Rattus norvegicus 280 ChEMBL 10.1021/jm00071a007 10.7270/Q2B858RJ 8410990 Bogeso, KP; Arnt, J; Hyttel, J; Pedersen, H H. Lundbeck A/S http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368661&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9913230 160847763 CHEMBL1744121 ZINC22940772 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50671217 CN(C)C1CC(c2ccccc2)c2cc(O)c(O)cc2C1 InChI=1S/C18H21NO2/c1-19(2)14-8-13-9-17(20)18(21)11-16(13)15(10-14)12-6-4-3-5-7-12/h3-7,9,11,14-15,20-21H,8,10H2,1-2H3 IFDQCFBQHUVXHV-UHFFFAOYSA-N 50040281 CHEMBL105645::CHEMBL543134::cis-7-Dimethylamino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide::trans-7-Dimethylamino-5-phenyl-5,6,7,8-tetrahydro-naphthalene-2,3-diol; hydrobromide D(2) dopamine receptor Rattus norvegicus >5000 ChEMBL 10.1021/jm00069a013 10.7270/Q2C53MGM 8102651 Wyrick, SD; Booth, RG; Myers, AM; Owens, CE; Kula, NS; Baldessarini, RJ; McPhail, AT; Mailman, RB University of North Carolina http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50040281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50040281&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15657199 103972341 CHEMBL543134CHEMBL105645 ZINC26571926 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787205 COC(=O)C1(CC1CN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccccc1 InChI=1S/C23H26ClNO3/c1-28-21(26)23(18-5-3-2-4-6-18)15-19(23)16-25-13-11-22(27,12-14-25)17-7-9-20(24)10-8-17/h2-10,19,27H,11-16H2,1H3 XQIPLSFFYJNKFR-UHFFFAOYSA-N 50251204 CHEMBL4075591 D(2) dopamine receptor Rattus norvegicus 5200 ChEMBL 10.1021/acs.jmedchem.7b01584 10.7270/Q2319Z9X 29220177 Amata, E; Rescifina, A; Prezzavento, O; Arena, E; Dichiara, M; Pittalà, V; Montilla-García, Á; Punzo, F; Merino, P; Cobos, EJ; Marrazzo, A Universit£ di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251204&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73016448 401962644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787212 COC(=O)[C@@]1(C[C@H]1CN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccccc1 InChI=1S/C23H26ClNO3/c1-28-21(26)23(18-5-3-2-4-6-18)15-19(23)16-25-13-11-22(27,12-14-25)17-7-9-20(24)10-8-17/h2-10,19,27H,11-16H2,1H3/t19-,23-/m0/s1 XQIPLSFFYJNKFR-CVDCTZTESA-N 50251205 CHEMBL4070836 D(2) dopamine receptor Rattus norvegicus 5624 ChEMBL 10.1021/acs.jmedchem.7b01584 10.7270/Q2319Z9X 29220177 Amata, E; Rescifina, A; Prezzavento, O; Arena, E; Dichiara, M; Pittalà, V; Montilla-García, Á; Punzo, F; Merino, P; Cobos, EJ; Marrazzo, A Universit£ di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251205 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251205&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 137639092 401962645 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787259 COC(=O)[C@]1(C[C@@H]1CN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccccc1 InChI=1S/C23H26ClNO3/c1-28-21(26)23(18-5-3-2-4-6-18)15-19(23)16-25-13-11-22(27,12-14-25)17-7-9-20(24)10-8-17/h2-10,19,27H,11-16H2,1H3/t19-,23-/m1/s1 XQIPLSFFYJNKFR-AUSIDOKSSA-N 50251207 CHEMBL4079633 D(2) dopamine receptor Rattus norvegicus 4970 ChEMBL 10.1021/acs.jmedchem.7b01584 10.7270/Q2319Z9X 29220177 Amata, E; Rescifina, A; Prezzavento, O; Arena, E; Dichiara, M; Pittalà, V; Montilla-García, Á; Punzo, F; Merino, P; Cobos, EJ; Marrazzo, A Universit£ di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251207 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251207&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 137652401 401962646 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787261 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2.1 ChEMBL 10.1021/acs.jmedchem.7b01584 10.7270/Q2319Z9X 29220177 Amata, E; Rescifina, A; Prezzavento, O; Arena, E; Dichiara, M; Pittalà, V; Montilla-García, Á; Punzo, F; Merino, P; Cobos, EJ; Marrazzo, A Universit£ di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787175 COC(=O)C1(CC1CN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccccc1 InChI=1S/C23H26ClNO3/c1-28-21(26)23(18-5-3-2-4-6-18)15-19(23)16-25-13-11-22(27,12-14-25)17-7-9-20(24)10-8-17/h2-10,19,27H,11-16H2,1H3 XQIPLSFFYJNKFR-UHFFFAOYSA-N 50251204 CHEMBL4075591 D(2) dopamine receptor Rattus norvegicus 5200 ChEMBL 10.1021/acs.jmedchem.7b01584 10.7270/Q2319Z9X 29220177 Amata, E; Rescifina, A; Prezzavento, O; Arena, E; Dichiara, M; Pittalà, V; Montilla-García, Á; Punzo, F; Merino, P; Cobos, EJ; Marrazzo, A Universit£ di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251204&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73016448 401962644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 50787208 COC(=O)C1(CC1CN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccccc1 InChI=1S/C23H26ClNO3/c1-28-21(26)23(18-5-3-2-4-6-18)15-19(23)16-25-13-11-22(27,12-14-25)17-7-9-20(24)10-8-17/h2-10,19,27H,11-16H2,1H3 XQIPLSFFYJNKFR-UHFFFAOYSA-N 50251204 CHEMBL4075591 D(2) dopamine receptor Rattus norvegicus 378 ChEMBL 10.1021/acs.jmedchem.7b01584 10.7270/Q2319Z9X 29220177 Amata, E; Rescifina, A; Prezzavento, O; Arena, E; Dichiara, M; Pittalà, V; Montilla-García, Á; Punzo, F; Merino, P; Cobos, EJ; Marrazzo, A Universit£ di Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50251204 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50251204&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73016448 401962644 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164250 Fc1ccc(cc1)C(=O)CCCN1CCN2Cc3[nH]c4ccccc4c3CC2C1 InChI=1S/C24H26FN3O/c25-18-9-7-17(8-10-18)24(29)6-3-11-27-12-13-28-16-23-21(14-19(28)15-27)20-4-1-2-5-22(20)26-23/h1-2,4-5,7-10,19,26H,3,6,11-16H2 YCNCIZWAGQTWBI-UHFFFAOYSA-N 50133931 1-(4-fluoro-phenyl)-4-(3,4,6,7,12,12a-hexahydro-1H-pyrazino[1',2':1,6]pyrido[3,4-b]indol-2-yl)-butan-1-one::Biriperone::CHEMBL136711 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1016/j.bmc.2007.07.018 10.7270/Q251420V 17869521 Chakrabarty, R; Rao, J; Anand, A; Roy, AD; Roy, R; Shankar, G; Dua, PR; Saxena, AK Central Drug Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50133931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50133931&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68663 104024636 CHEMBL136711 ZINC22043131 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164255 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.501187 ChEMBL 10.1016/j.bmc.2007.07.018 10.7270/Q251420V 17869521 Chakrabarty, R; Rao, J; Anand, A; Roy, AD; Roy, R; Shankar, G; Dua, PR; Saxena, AK Central Drug Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164256 Fc1ccc(cc1)C(=O)CCCN1C2CN3CCNCC3CC2c2ccccc12 InChI=1S/C24H28FN3O/c25-18-9-7-17(8-10-18)24(29)6-3-12-28-22-5-2-1-4-20(22)21-14-19-15-26-11-13-27(19)16-23(21)28/h1-2,4-5,7-10,19,21,23,26H,3,6,11-16H2 IIYOGQVRYCSVTF-UHFFFAOYSA-N 50477150 CHEMBL240733 D(2) dopamine receptor Rattus norvegicus <100000 ChEMBL 10.1016/j.bmc.2007.07.018 10.7270/Q251420V 17869521 Chakrabarty, R; Rao, J; Anand, A; Roy, AD; Roy, R; Shankar, G; Dua, PR; Saxena, AK Central Drug Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50477150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50477150&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44437168 433944415 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164261 Fc1ccc(cc1)C(=O)CCCN1C2CN3CCN(CCCC(=O)c4ccc(F)cc4)CC3CC2c2ccccc12 InChI=1S/C34H37F2N3O2/c35-26-13-9-24(10-14-26)33(40)7-3-17-37-19-20-38-23-32-30(21-28(38)22-37)29-5-1-2-6-31(29)39(32)18-4-8-34(41)25-11-15-27(36)16-12-25/h1-2,5-6,9-16,28,30,32H,3-4,7-8,17-23H2 TXPXVUNBDQGBPQ-UHFFFAOYSA-N 50477152 CHEMBL393466 D(2) dopamine receptor Rattus norvegicus 2254 ChEMBL 10.1016/j.bmc.2007.07.018 10.7270/Q251420V 17869521 Chakrabarty, R; Rao, J; Anand, A; Roy, AD; Roy, R; Shankar, G; Dua, PR; Saxena, AK Central Drug Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50477152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50477152&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24873463 433944417 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164262 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1016/j.bmc.2007.07.018 10.7270/Q251420V 17869521 Chakrabarty, R; Rao, J; Anand, A; Roy, AD; Roy, R; Shankar, G; Dua, PR; Saxena, AK Central Drug Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164263 Fc1ccc(cc1)C(=O)CCCN1CCN2CC3Nc4ccccc4C3CC2C1 InChI=1S/C24H28FN3O/c25-18-9-7-17(8-10-18)24(29)6-3-11-27-12-13-28-16-23-21(14-19(28)15-27)20-4-1-2-5-22(20)26-23/h1-2,4-5,7-10,19,21,23,26H,3,6,11-16H2 IDALQZYWDCMROB-UHFFFAOYSA-N 50477151 CHEMBL393622 D(2) dopamine receptor Rattus norvegicus 94 ChEMBL 10.1016/j.bmc.2007.07.018 10.7270/Q251420V 17869521 Chakrabarty, R; Rao, J; Anand, A; Roy, AD; Roy, R; Shankar, G; Dua, PR; Saxena, AK Central Drug Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50477151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50477151&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44437167 433944416 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164266 FC(F)(F)c1cccc(c1)N1CCN(CCCOc2ccc3[nH]c(=S)[nH]c3c2)CC1 InChI=1S/C21H23F3N4OS/c22-21(23,24)15-3-1-4-16(13-15)28-10-8-27(9-11-28)7-2-12-29-17-5-6-18-19(14-17)26-20(30)25-18/h1,3-6,13-14H,2,7-12H2,(H2,25,26,30) OUZRREWIEFENOJ-UHFFFAOYSA-N 50477154 CHEMBL237133 D(2) dopamine receptor Rattus norvegicus 363 ChEMBL 10.1016/j.bmcl.2007.08.066 10.7270/Q218399K 17870534 Tomić, M; Ignjatović, D; Tovilović, G; Andrić, D; Roglić, G; Kostić-Rajacić, S Institute for Biological Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50477154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50477154&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44433309 433944419 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164267 FC(F)(F)c1cccc(c1)N1CCN(CCCOc2ccc3[nH]cnc3c2)CC1 InChI=1S/C21H23F3N4O/c22-21(23,24)16-3-1-4-17(13-16)28-10-8-27(9-11-28)7-2-12-29-18-5-6-19-20(14-18)26-15-25-19/h1,3-6,13-15H,2,7-12H2,(H,25,26) KTCIPRZIPCMOSO-UHFFFAOYSA-N 50477155 CHEMBL237135 D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1016/j.bmcl.2007.08.066 10.7270/Q218399K 17870534 Tomić, M; Ignjatović, D; Tovilović, G; Andrić, D; Roglić, G; Kostić-Rajacić, S Institute for Biological Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50477155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50477155&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44433311 433944420 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164273 S=c1[nH]c2ccc(OCCCN3CCN(CC3)c3ccccc3)cc2[nH]1 InChI=1S/C20H24N4OS/c26-20-21-18-8-7-17(15-19(18)22-20)25-14-4-9-23-10-12-24(13-11-23)16-5-2-1-3-6-16/h1-3,5-8,15H,4,9-14H2,(H2,21,22,26) GHQWVUHZBUDXSH-UHFFFAOYSA-N 50477157 CHEMBL236929 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1016/j.bmcl.2007.08.066 10.7270/Q218399K 17870534 Tomić, M; Ignjatović, D; Tovilović, G; Andrić, D; Roglić, G; Kostić-Rajacić, S Institute for Biological Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50477157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50477157&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44433307 433944422 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164274 COc1ccccc1N1CCN(CCCOc2ccc3[nH]c(=S)[nH]c3c2)CC1 InChI=1S/C21H26N4O2S/c1-26-20-6-3-2-5-19(20)25-12-10-24(11-13-25)9-4-14-27-16-7-8-17-18(15-16)23-21(28)22-17/h2-3,5-8,15H,4,9-14H2,1H3,(H2,22,23,28) FUSUKSWNUZIJFY-UHFFFAOYSA-N 50477156 CHEMBL396881 D(2) dopamine receptor Rattus norvegicus 1.7 ChEMBL 10.1016/j.bmcl.2007.08.066 10.7270/Q218399K 17870534 Tomić, M; Ignjatović, D; Tovilović, G; Andrić, D; Roglić, G; Kostić-Rajacić, S Institute for Biological Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50477156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50477156&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44433308 433944421 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164276 COc1ccccc1N1CCN(CCCOc2ccc3[nH]cnc3c2)CC1 InChI=1S/C21H26N4O2/c1-26-21-6-3-2-5-20(21)25-12-10-24(11-13-25)9-4-14-27-17-7-8-18-19(15-17)23-16-22-18/h2-3,5-8,15-16H,4,9-14H2,1H3,(H,22,23) UYUSPOUKBUGCQZ-UHFFFAOYSA-N 50477153 CHEMBL237134 D(2) dopamine receptor Rattus norvegicus 8.7 ChEMBL 10.1016/j.bmcl.2007.08.066 10.7270/Q218399K 17870534 Tomić, M; Ignjatović, D; Tovilović, G; Andrić, D; Roglić, G; Kostić-Rajacić, S Institute for Biological Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50477153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50477153&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44433310 433944418 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164280 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 145 ChEMBL 10.1016/j.bmcl.2007.08.066 10.7270/Q218399K 17870534 Tomić, M; Ignjatović, D; Tovilović, G; Andrić, D; Roglić, G; Kostić-Rajacić, S Institute for Biological Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51164285 C(COc1ccc2[nH]cnc2c1)CN1CCN(CC1)c1ccccc1 InChI=1S/C20H24N4O/c1-2-5-17(6-3-1)24-12-10-23(11-13-24)9-4-14-25-18-7-8-19-20(15-18)22-16-21-19/h1-3,5-8,15-16H,4,9-14H2,(H,21,22) RXYZMKZMRDRWHL-UHFFFAOYSA-N 50477158 CHEMBL396882 D(2) dopamine receptor Rattus norvegicus 76 ChEMBL 10.1016/j.bmcl.2007.08.066 10.7270/Q218399K 17870534 Tomić, M; Ignjatović, D; Tovilović, G; Andrić, D; Roglić, G; Kostić-Rajacić, S Institute for Biological Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50477158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50477158&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21276138 433944423 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162298 CC(C)Oc1ccccc1OCCNCc1cccc(c1)-c1cccs1 InChI=1S/C22H25NO2S/c1-17(2)25-21-10-4-3-9-20(21)24-13-12-23-16-18-7-5-8-19(15-18)22-11-6-14-26-22/h3-11,14-15,17,23H,12-13,16H2,1-2H3 ZFRCVULPGRUJCI-UHFFFAOYSA-N 50476115 CHEMBL425810 D(2) dopamine receptor Rattus norvegicus 0.562341 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476115&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109492 433943380 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162300 CC(C)Oc1ccccc1OCCNCc1cccc(c1)C1=CCCC1 InChI=1S/C23H29NO2/c1-18(2)26-23-13-6-5-12-22(23)25-15-14-24-17-19-8-7-11-21(16-19)20-9-3-4-10-20/h5-9,11-13,16,18,24H,3-4,10,14-15,17H2,1-2H3 VSFLBLRRRAGBMV-UHFFFAOYSA-N 50476116 CHEMBL220809 D(2) dopamine receptor Rattus norvegicus 0.501187 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476116&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109496 433943381 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162305 C(COc1cccc2OCCOc12)NCc1cccc(c1)C1=CCCC1 InChI=1S/C22H25NO3/c1-2-7-18(6-1)19-8-3-5-17(15-19)16-23-11-12-24-20-9-4-10-21-22(20)26-14-13-25-21/h3-6,8-10,15,23H,1-2,7,11-14,16H2 PTSYEFRBIUQVOF-UHFFFAOYSA-N 50476124 CHEMBL375297 D(2) dopamine receptor Rattus norvegicus 0.776247 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476124&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109486 433943389 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162306 Fc1ccc(cc1)-c1cncc(CN2CCN(CC2)c2cccc3OCCOc23)c1 InChI=1S/C24H24FN3O2/c25-21-6-4-19(5-7-21)20-14-18(15-26-16-20)17-27-8-10-28(11-9-27)22-2-1-3-23-24(22)30-13-12-29-23/h1-7,14-16H,8-13,17H2 IUVSEUFHPNITEQ-UHFFFAOYSA-N 248056 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]piperazine::Adoprazine D(2) dopamine receptor Rattus norvegicus 4.0 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=248056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=248056&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9887537 346542586 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162308 Fc1ccc(cc1)-c1cncc(CNC[C@H]2CCc3ccccc3O2)c1 InChI=1S/C22H21FN2O/c23-20-8-5-17(6-9-20)19-11-16(12-24-14-19)13-25-15-21-10-7-18-3-1-2-4-22(18)26-21/h1-6,8-9,11-12,14,21,25H,7,10,13,15H2/t21-/m1/s1 HKFMQJUJWSFOLY-OAQYLSRUSA-N 50027256 Sarizotan D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50027256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50027256&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 6918388 277286710 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162309 CC(C)Oc1ccccc1OCCNCc1cccc(c1)C1=CCCCCC1 InChI=1S/C25H33NO2/c1-20(2)28-25-15-8-7-14-24(25)27-17-16-26-19-21-10-9-13-23(18-21)22-11-5-3-4-6-12-22/h7-11,13-15,18,20,26H,3-6,12,16-17,19H2,1-2H3 PSXLMQIRHAQLSY-UHFFFAOYSA-N 50476121 CHEMBL221957 D(2) dopamine receptor Rattus norvegicus 3.1 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109508 433943386 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162312 CC(C)Oc1ccccc1OCCNCc1cccc(c1)C1CC1 InChI=1S/C21H27NO2/c1-16(2)24-21-9-4-3-8-20(21)23-13-12-22-15-17-6-5-7-19(14-17)18-10-11-18/h3-9,14,16,18,22H,10-13,15H2,1-2H3 HAZWYJQEUAUPHQ-UHFFFAOYSA-N 50476122 CHEMBL219111 D(2) dopamine receptor Rattus norvegicus 0.602560 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476122&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109509 433943387 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162313 CC1(C)Oc2cccc(OCCNCc3cccc(c3)C3=CCCC3)c2O1 InChI=1S/C23H27NO3/c1-23(2)26-21-12-6-11-20(22(21)27-23)25-14-13-24-16-17-7-5-10-19(15-17)18-8-3-4-9-18/h5-8,10-12,15,24H,3-4,9,13-14,16H2,1-2H3 AYCDTYHHWKFGCP-UHFFFAOYSA-N 50476126 CHEMBL219486 D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476126&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109487 433943391 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162317 C(COc1cccc2OCOc12)NCc1cccc(c1)C1=CCCC1 InChI=1S/C21H23NO3/c1-2-7-17(6-1)18-8-3-5-16(13-18)14-22-11-12-23-19-9-4-10-20-21(19)25-15-24-20/h3-6,8-10,13,22H,1-2,7,11-12,14-15H2 SHOKZDRFBVVMHZ-UHFFFAOYSA-N 50476117 CHEMBL441546 D(2) dopamine receptor Rattus norvegicus 2.6 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476117&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109510 433943382 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162319 CCC1(C)Cc2cccc(OCCNCc3cccc(c3)C3=CCCC3)c2O1 InChI=1S/C25H31NO2/c1-3-25(2)17-22-12-7-13-23(24(22)28-25)27-15-14-26-18-19-8-6-11-21(16-19)20-9-4-5-10-20/h6-9,11-13,16,26H,3-5,10,14-15,17-18H2,1-2H3 VBGGWGMORHRQSH-UHFFFAOYSA-N 50476123 CHEMBL221131 D(2) dopamine receptor Rattus norvegicus 11 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476123&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109511 433943388 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162320 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus 550 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162321 CC1(C)Cc2cccc(OCCNCc3cncc(c3)C3=CCCC3)c2O1 InChI=1S/C23H28N2O2/c1-23(2)13-19-8-5-9-21(22(19)27-23)26-11-10-24-14-17-12-20(16-25-15-17)18-6-3-4-7-18/h5-6,8-9,12,15-16,24H,3-4,7,10-11,13-14H2,1-2H3 XJUROKFTAHXDMI-UHFFFAOYSA-N 50476128 CHEMBL384657 D(2) dopamine receptor Rattus norvegicus 0.275423 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476128&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10067360 433943393 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162324 C(COc1cccc2CC3(CC3)Oc12)NCc1cncc(c1)C1=CCCC1 InChI=1S/C23H26N2O2/c1-2-5-18(4-1)20-12-17(15-25-16-20)14-24-10-11-26-21-7-3-6-19-13-23(8-9-23)27-22(19)21/h3-4,6-7,12,15-16,24H,1-2,5,8-11,13-14H2 GKKAASDLBDVVHR-UHFFFAOYSA-N 50476120 CHEMBL221920 D(2) dopamine receptor Rattus norvegicus 0.446684 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109489 433943385 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162325 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 4.4 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162329 CC(C)Oc1ccccc1OCCNCc1cccc(c1)-c1ccsc1 InChI=1S/C22H25NO2S/c1-17(2)25-22-9-4-3-8-21(22)24-12-11-23-15-18-6-5-7-19(14-18)20-10-13-26-16-20/h3-10,13-14,16-17,23H,11-12,15H2,1-2H3 DRSYLBZPVRFSTI-UHFFFAOYSA-N 50476119 CHEMBL386988 D(2) dopamine receptor Rattus norvegicus 0.275423 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476119&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109482 433943384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162332 CC(C)Oc1ccccc1OCCNCc1cccc(c1)-c1ccccc1 InChI=1S/C24H27NO2/c1-19(2)27-24-14-7-6-13-23(24)26-16-15-25-18-20-9-8-12-22(17-20)21-10-4-3-5-11-21/h3-14,17,19,25H,15-16,18H2,1-2H3 UBZWXZBTCLQFRO-UHFFFAOYSA-N 50476127 CHEMBL218217 D(2) dopamine receptor Rattus norvegicus 0.194984 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476127&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109481 433943392 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162334 O=c1[nH]c2cccc(N3CCN(Cc4cccc(c4)-c4ccccc4)CC3)c2o1 InChI=1S/C24H23N3O2/c28-24-25-21-10-5-11-22(23(21)29-24)27-14-12-26(13-15-27)17-18-6-4-9-20(16-18)19-7-2-1-3-8-19/h1-11,16H,12-15,17H2,(H,25,28) CYGODHVAJQTCBG-UHFFFAOYSA-N 50241119 7-(4-Biphenyl-3-ylmethyl-piperazin-1-yl)-3H-benzooxazol-2-one::BIFEPRUNOX::CHEMBL218166 D(2) dopamine receptor Rattus norvegicus 1.5 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241119&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 208951 104098615 CHEMBL218166 DB04888 ZINC52971454 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162339 CC(C)Oc1ccccc1OCCNCc1cccc(c1)-c1ccco1 InChI=1S/C22H25NO3/c1-17(2)26-22-10-4-3-9-21(22)25-14-12-23-16-18-7-5-8-19(15-18)20-11-6-13-24-20/h3-11,13,15,17,23H,12,14,16H2,1-2H3 XBTWMNHXNQEYOC-UHFFFAOYSA-N 50476125 CHEMBL376634 D(2) dopamine receptor Rattus norvegicus 0.338844 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476125&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109483 433943390 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162342 CC(C)Oc1ccccc1OCCNCc1cccc(c1)C1=CCCCC1 InChI=1S/C24H31NO2/c1-19(2)27-24-14-7-6-13-23(24)26-16-15-25-18-20-9-8-12-22(17-20)21-10-4-3-5-11-21/h6-10,12-14,17,19,25H,3-5,11,15-16,18H2,1-2H3 DNILKHNIQCTYMS-UHFFFAOYSA-N 50476118 CHEMBL221743 D(2) dopamine receptor Rattus norvegicus 1.5 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109484 433943383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162349 CC(C)Oc1ccccc1OCCNCc1cccc(c1)C1CCCC1 InChI=1S/C23H31NO2/c1-18(2)26-23-13-6-5-12-22(23)25-15-14-24-17-19-8-7-11-21(16-19)20-9-3-4-10-20/h5-8,11-13,16,18,20,24H,3-4,9-10,14-15,17H2,1-2H3 ACEXCRCRDMOWEM-UHFFFAOYSA-N 50476130 CHEMBL413777 D(2) dopamine receptor Rattus norvegicus 0.562341 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476130&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109485 433943395 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162352 CC1(C)COc2c1cccc2OCCNCc1cccc(c1)C1=CCCC1 InChI=1S/C24H29NO2/c1-24(2)17-27-23-21(24)11-6-12-22(23)26-14-13-25-16-18-7-5-10-20(15-18)19-8-3-4-9-19/h5-8,10-12,15,25H,3-4,9,13-14,16-17H2,1-2H3 MXPWGHGCCKQDEC-UHFFFAOYSA-N 50476129 CHEMBL221183 D(2) dopamine receptor Rattus norvegicus 0.812831 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476129&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 16109488 433943394 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162357 C(COc1cccc2CC3(CC3)Oc12)NCc1cccc(c1)C1=CCCC1 InChI=1S/C24H27NO2/c1-2-7-19(6-1)20-8-3-5-18(15-20)17-25-13-14-26-22-10-4-9-21-16-24(11-12-24)27-23(21)22/h3-6,8-10,15,25H,1-2,7,11-14,16-17H2 VTZTXBSFXXIRQU-UHFFFAOYSA-N 50476131 CHEMBL218313 D(2) dopamine receptor Rattus norvegicus 1.1 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476131&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9863750 433943396 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51162360 CC1(C)Cc2cccc(OCCNCc3cccc(c3)C3=CCCC3)c2O1 InChI=1S/C24H29NO2/c1-24(2)16-21-11-6-12-22(23(21)27-24)26-14-13-25-17-18-7-5-10-20(15-18)19-8-3-4-9-19/h5-8,10-12,15,25H,3-4,9,13-14,16-17H2,1-2H3 RAIDOKRWKAIHOH-UHFFFAOYSA-N 50476132 CHEMBL218261 D(2) dopamine receptor Rattus norvegicus 0.416869 ChEMBL 10.1021/jm061180b 10.7270/Q2ZS309D 17300168 Cuisiat, S; Bourdiol, N; Lacharme, V; Newman-Tancredi, A; Colpaert, F; Vacher, B Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50476132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50476132&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10248159 433943397 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51149280 OC(CC=N)CC1CCN(CC1)c1ccccc1Oc1ccccc1 InChI=1S/C21H26N2O2/c22-13-10-18(24)16-17-11-14-23(15-12-17)20-8-4-5-9-21(20)25-19-6-2-1-3-7-19/h1-9,13,17-18,22,24H,10-12,14-16H2 MOVYLDZUBGRMTA-UHFFFAOYSA-N 50470945 CHEMBL140450 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm960510x 10.7270/Q29W0J6P 8917649 Giardinà, D; Crucianelli, M; Romanelli, R; Leonardi, A; Poggesi, E; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50470945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50470945&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44361064 433938210 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51149283 COc1cc2nc(nc(N)c2cc1OC)N1CCN(C2CCCCC12)C(=O)c1ccco1 InChI=1S/C23H27N5O4/c1-30-19-12-14-15(13-20(19)31-2)25-23(26-21(14)24)28-10-9-27(16-6-3-4-7-17(16)28)22(29)18-8-5-11-32-18/h5,8,11-13,16-17H,3-4,6-7,9-10H2,1-2H3,(H2,24,25,26) XBRXTUGRUXGBPX-UHFFFAOYSA-N 50122826 (Cyclazosin)[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone::CHEMBL97698::[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm960510x 10.7270/Q29W0J6P 8917649 Giardinà, D; Crucianelli, M; Romanelli, R; Leonardi, A; Poggesi, E; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122826&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search T0B 7B6W 2894 104015445 CHEMBL97698 486 ZINC03872168 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51149288 COc1cc2nc(nc(N)c2cc1OC)N1CCN([C@@H]2CCCC[C@H]12)C(=O)c1ccco1 InChI=1S/C23H27N5O4/c1-30-19-12-14-15(13-20(19)31-2)25-23(26-21(14)24)28-10-9-27(16-6-3-4-7-17(16)28)22(29)18-8-5-11-32-18/h5,8,11-13,16-17H,3-4,6-7,9-10H2,1-2H3,(H2,24,25,26)/t16-,17+/m1/s1 XBRXTUGRUXGBPX-SJORKVTESA-N 50274049 CHEMBL342062 D(2) dopamine receptor Rattus norvegicus 8318 ChEMBL 10.1021/jm960510x 10.7270/Q29W0J6P 8917649 Giardinà, D; Crucianelli, M; Romanelli, R; Leonardi, A; Poggesi, E; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274049&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9824384 405256755 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51149312 COc1cc2nc(nc(N)c2cc1OC)N1CCN([C@H]2CCCC[C@@H]12)C(=O)c1ccco1 InChI=1S/C23H27N5O4/c1-30-19-12-14-15(13-20(19)31-2)25-23(26-21(14)24)28-10-9-27(16-6-3-4-7-17(16)28)22(29)18-8-5-11-32-18/h5,8,11-13,16-17H,3-4,6-7,9-10H2,1-2H3,(H2,24,25,26)/t16-,17+/m0/s1 XBRXTUGRUXGBPX-DLBZAZTESA-N 50403649 CYCLAZOSIN D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm960510x 10.7270/Q29W0J6P 8917649 Giardinà, D; Crucianelli, M; Romanelli, R; Leonardi, A; Poggesi, E; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50403649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50403649&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search T0B 7B6W 132266 163352673 63937 ZINC02385764 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51149316 Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) DKGZKTPJOSAWFA-UHFFFAOYSA-N 21397 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::CHEMBL267930::MLS000028615::SMR000058674::SPIPERONE::Spiroperidol::US9359372, Spiperone::[3H]-Spiroperidol::cid_5265 D(2) dopamine receptor Rattus norvegicus 0.575440 ChEMBL 10.1021/jm960510x 10.7270/Q29W0J6P 8917649 Giardinà, D; Crucianelli, M; Romanelli, R; Leonardi, A; Poggesi, E; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21397&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search SIP 7DFP 5265 49689469 9233 CHEMBL267930 99 ZINC00643233 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51149319 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22) IENZQIKPVFGBNW-UHFFFAOYSA-N 29568 CHEMBL2::PRAZOSIN::PRAZOSIN HYDROCHLORIDE::[3H]-Furazosin::[3H]-Minipress::[3H]-Pratsiol::[3H]-Prazosin D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm960510x 10.7270/Q29W0J6P 8917649 Giardinà, D; Crucianelli, M; Romanelli, R; Leonardi, A; Poggesi, E; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search XRA 3OWX 4893 81054997 8364 CHEMBL2 DB00457 503 C07368 ZINC00601304 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150493 Oc1ccc2n(Cc3ccccc3)c(nc2c1)N1CCNCC1 InChI=1S/C18H20N4O/c23-15-6-7-17-16(12-15)20-18(21-10-8-19-9-11-21)22(17)13-14-4-2-1-3-5-14/h1-7,12,19,23H,8-11,13H2 GBIHCCAAGLOCEZ-UHFFFAOYSA-N 50471501 CHEMBL62692 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471501&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10804748 433938766 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152693 Fc1ccc(cc1)C(=O)C1CCN(CC2CC(=O)c3ccccc3C2)CC1 InChI=1S/C23H24FNO2/c24-20-7-5-17(6-8-20)23(27)18-9-11-25(12-10-18)15-16-13-19-3-1-2-4-21(19)22(26)14-16/h1-8,16,18H,9-15H2 JFVJCLYJXOVMSI-UHFFFAOYSA-N 50409510 CHEMBL308480 D(2) dopamine receptor Rattus norvegicus 21 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15021876 163358534 CHEMBL308480 ZINC12356211 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152694 COc1ccccc1N1CCN(CC2CC(=O)c3ccccc23)CC1 InChI=1S/C21H24N2O2/c1-25-21-9-5-4-8-19(21)23-12-10-22(11-13-23)15-16-14-20(24)18-7-3-2-6-17(16)18/h2-9,16H,10-15H2,1H3 BWXXICDWJZUZDM-UHFFFAOYSA-N 50409513 CHEMBL444269 D(2) dopamine receptor Rattus norvegicus 646 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10544858 163358537 CHEMBL444269 ZINC13471603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152699 Fc1ccc2c(noc2c1)C1CCN(CC2Cc3sccc3C(=O)C2)CC1 InChI=1S/C21H21FN2O2S/c22-15-1-2-17-19(11-15)26-23-21(17)14-3-6-24(7-4-14)12-13-9-18(25)16-5-8-27-20(16)10-13/h1-2,5,8,11,13-14H,3-4,6-7,9-10,12H2 UUWNMTNBWJAYKN-UHFFFAOYSA-N 50409517 CHEMBL320572 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44326751 163358541 CHEMBL320572 ZINC12356226 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152701 Fc1ccc(cc1)C(=O)CCCN1CCN(CC2CC(=O)c3ccccc23)CC1 InChI=1S/C24H27FN2O2/c25-20-9-7-18(8-10-20)23(28)6-3-11-26-12-14-27(15-13-26)17-19-16-24(29)22-5-2-1-4-21(19)22/h1-2,4-5,7-10,19H,3,6,11-17H2 DLVXCUGDQCNSLY-UHFFFAOYSA-N 50409505 CHEMBL111509 D(2) dopamine receptor Rattus norvegicus 324 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10810641 163358529 CHEMBL111509 ZINC22793170 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152703 Fc1ccc(cc1)C(=O)CCCN1CCN(CCC2Cc3ccccc3C2=O)CC1 InChI=1S/C25H29FN2O2/c26-22-9-7-19(8-10-22)24(29)6-3-12-27-14-16-28(17-15-27)13-11-21-18-20-4-1-2-5-23(20)25(21)30/h1-2,4-5,7-10,21H,3,6,11-18H2 ZOXIJGNVMSVOEF-UHFFFAOYSA-N 50409491 CHEMBL95098 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409491&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10024430 163358515 CHEMBL95098 ZINC22033457 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152704 Fc1ccc(cc1)C(=O)C1CCN(CCC2CCc3sccc3C2=O)CC1 InChI=1S/C22H24FNO2S/c23-18-4-1-15(2-5-18)21(25)17-8-12-24(13-9-17)11-7-16-3-6-20-19(22(16)26)10-14-27-20/h1-2,4-5,10,14,16-17H,3,6-9,11-13H2 AJNQCCIFRZGSQR-UHFFFAOYSA-N 50409522 CHEMBL109673 D(2) dopamine receptor Rattus norvegicus 209 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10249506 163358546 CHEMBL109673 ZINC12356216 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152710 Cl.Fc1ccc2c(noc2c1)C1CCN(CCC2CCc3ccsc3C2=O)CC1 InChI=1S/C22H23FN2O2S.ClH/c23-17-3-4-18-19(13-17)27-24-20(18)14-5-9-25(10-6-14)11-7-15-1-2-16-8-12-28-22(16)21(15)26;/h3-4,8,12-15H,1-2,5-7,9-11H2;1H VCVKDKPZVLKZPY-UHFFFAOYSA-N 50472324 CHEMBL541842 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45264926 433939589 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150502 COc1ccc2nc(N3CCNCC3)n(Cc3ccccc3)c2c1 InChI=1S/C19H22N4O/c1-24-16-7-8-17-18(13-16)23(14-15-5-3-2-4-6-15)19(21-17)22-11-9-20-10-12-22/h2-8,13,20H,9-12,14H2,1H3 FWYSFXFCGNZNMX-UHFFFAOYSA-N 50471505 CHEMBL64801 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10543852 433938770 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150506 Fc1ccc2n(Cc3ccccc3)c(nc2c1)N1CCNCC1 InChI=1S/C18H19FN4/c19-15-6-7-17-16(12-15)21-18(22-10-8-20-9-11-22)23(17)13-14-4-2-1-3-5-14/h1-7,12,20H,8-11,13H2 MMIDVSOIHUMUKV-UHFFFAOYSA-N 50471508 CHEMBL63025 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471508&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9839681 433938773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150507 Clc1cc2nc(N3CCNCC3)n(Cc3ccccc3)c2cc1Cl InChI=1S/C18H18Cl2N4/c19-14-10-16-17(11-15(14)20)24(12-13-4-2-1-3-5-13)18(22-16)23-8-6-21-7-9-23/h1-5,10-11,21H,6-9,12H2 XFUOIMWLAPSVGQ-UHFFFAOYSA-N 50471509 CHEMBL64489 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10498784 433938774 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150510 C(c1ccccc1)n1c(nc2ccccc12)N1CCNCC1 InChI=1S/C18H20N4/c1-2-6-15(7-3-1)14-22-17-9-5-4-8-16(17)20-18(22)21-12-10-19-11-13-21/h1-9,19H,10-14H2 PWWDCRQZITYKDV-UHFFFAOYSA-N 50103072 1-Benzyl-2-piperazin-1-yl-1H-benzoimidazole::CHEMBL56900::Lerisetron D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103072&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 65997 103999419 CHEMBL56900 ZINC00007943 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150513 COc1cccc2n(Cc3ccccc3)c(nc12)N1CCNCC1 InChI=1S/C19H22N4O/c1-24-17-9-5-8-16-18(17)21-19(22-12-10-20-11-13-22)23(16)14-15-6-3-2-4-7-15/h2-9,20H,10-14H2,1H3 XJFVRGTXVRPNMX-UHFFFAOYSA-N 50471502 CHEMBL64060 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471502&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10853289 433938767 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150522 COc1ccc2n(Cc3ccccc3)c(nc2c1)N1CCNCC1 InChI=1S/C19H22N4O/c1-24-16-7-8-18-17(13-16)21-19(22-11-9-20-10-12-22)23(18)14-15-5-3-2-4-6-15/h2-8,13,20H,9-12,14H2,1H3 GNPGYSPKCSSKDQ-UHFFFAOYSA-N 50471512 CHEMBL62778 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471512&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10519883 433938777 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150523 Cn1c(nc2ccccc12)N1CCNCC1 InChI=1S/C12H16N4/c1-15-11-5-3-2-4-10(11)14-12(15)16-8-6-13-7-9-16/h2-5,13H,6-9H2,1H3 XBTIVKKHGCXLGP-UHFFFAOYSA-N 50471513 CHEMBL62270 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 667551 433938778 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150538 Oc1ccc2nc(N3CCNCC3)n(Cc3ccccc3)c2c1 InChI=1S/C18H20N4O/c23-15-6-7-16-17(12-15)22(13-14-4-2-1-3-5-14)18(20-16)21-10-8-19-9-11-21/h1-7,12,19,23H,8-11,13H2 HLYAGHNCWJSUKC-UHFFFAOYSA-N 50471500 CHEMBL59689 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471500&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10357932 433938765 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150539 Cc1ccc2n(Cc3ccccc3)c(nc2c1)N1CCNCC1 InChI=1S/C19H22N4/c1-15-7-8-18-17(13-15)21-19(22-11-9-20-10-12-22)23(18)14-16-5-3-2-4-6-16/h2-8,13,20H,9-12,14H2,1H3 VEFKMPXOOGXXSQ-UHFFFAOYSA-N 50471504 CHEMBL294522 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471504&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10614626 433938769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150543 COc1cccc2nc(N3CCNCC3)n(Cc3ccccc3)c12 InChI=1S/C19H22N4O/c1-24-17-9-5-8-16-18(17)23(14-15-6-3-2-4-7-15)19(21-16)22-12-10-20-11-13-22/h2-9,20H,10-14H2,1H3 OEYYBTWYWCTDKU-UHFFFAOYSA-N 50471511 CHEMBL294109 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471511&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11723654 433938776 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150545 CCn1c(nc2ccccc12)N1CCNCC1 InChI=1S/C13H18N4/c1-2-17-12-6-4-3-5-11(12)15-13(17)16-9-7-14-8-10-16/h3-6,14H,2,7-10H2,1H3 LQERTCSWJVMEIY-UHFFFAOYSA-N 50471507 CHEMBL64782 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471507&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10823368 433938772 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150551 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 0.630957 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150553 C1CC1n1c(nc2ccccc12)N1CCNCC1 InChI=1S/C14H18N4/c1-2-4-13-12(3-1)16-14(18(13)11-5-6-11)17-9-7-15-8-10-17/h1-4,11,15H,5-10H2 FMLVXBNJACPTIP-UHFFFAOYSA-N 50471503 CHEMBL60102 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10562150 433938768 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150556 CCCn1c(nc2ccccc12)N1CCNCC1 InChI=1S/C14H20N4/c1-2-9-18-13-6-4-3-5-12(13)16-14(18)17-10-7-15-8-11-17/h3-6,15H,2,7-11H2,1H3 XDHIOZBDJAHMKX-UHFFFAOYSA-N 50471506 CHEMBL60103 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471506&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10752839 433938771 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152721 Fc1ccc2c(noc2c1)C1CCN(CCC2CCc3sccc3C2=O)CC1 InChI=1S/C22H23FN2O2S/c23-16-2-3-17-19(13-16)27-24-21(17)14-5-9-25(10-6-14)11-7-15-1-4-20-18(22(15)26)8-12-28-20/h2-3,8,12-15H,1,4-7,9-11H2 YXDUNIOKKMVMKO-UHFFFAOYSA-N 50409515 CHEMBL110948::QF-0610B D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10367486 163358539 CHEMBL110948 ZINC13471676 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152722 CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 GOTMKOSCLKVOGG-OAHLLOKOSA-N 82247 8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390)::CAS_87134-87-0::CHEMBL2158641::CHEMBL62::SCH 23388::SCH 23390::SCH 23390 (R-enantiomer)::SCH 23390,R(+) D(2) dopamine receptor Rattus norvegicus 0.537032 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3036864 136350219 CHEMBL62CHEMBL2158641 ZINC02017838 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152723 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 8.1 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152725 Cl.Fc1ccc2c(noc2c1)C1CCN(CCC2Cc3sccc3C2=O)CC1 InChI=1S/C21H21FN2O2S.ClH/c22-15-1-2-16-18(12-15)26-23-20(16)13-3-7-24(8-4-13)9-5-14-11-19-17(21(14)25)6-10-27-19;/h1-2,6,10,12-14H,3-5,7-9,11H2;1H IVRAGKJZKRSHGQ-UHFFFAOYSA-N 50472325 CHEMBL554199 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 45261112 433939590 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152726 Fc1ccc(cc1)C(=O)CCCN1CCN(CCC2Cc3sccc3C2=O)CC1 InChI=1S/C23H27FN2O2S/c24-19-5-3-17(4-6-19)21(27)2-1-9-25-11-13-26(14-12-25)10-7-18-16-22-20(23(18)28)8-15-29-22/h3-6,8,15,18H,1-2,7,9-14,16H2 AFYKQUVNHCGGNK-UHFFFAOYSA-N 50409516 CHEMBL95112 D(2) dopamine receptor Rattus norvegicus 263 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10093238 163358540 CHEMBL95112 ZINC22774885 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152731 COc1ccccc1N1CCN(CCC2CCc3sccc3C2=O)CC1 InChI=1S/C21H26N2O2S/c1-25-19-5-3-2-4-18(19)23-13-11-22(12-14-23)10-8-16-6-7-20-17(21(16)24)9-15-26-20/h2-5,9,15-16H,6-8,10-14H2,1H3 HIFLACAUPGVDAM-UHFFFAOYSA-N 50409508 CHEMBL110847 D(2) dopamine receptor Rattus norvegicus 162 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409508&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809188 163358532 CHEMBL110847 ZINC13471668 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152732 Fc1ccc(cc1)C(=O)C1CCN(CCC2CCCc3ccccc3C2=O)CC1 InChI=1S/C25H28FNO2/c26-22-10-8-20(9-11-22)24(28)21-13-16-27(17-14-21)15-12-19-6-3-5-18-4-1-2-7-23(18)25(19)29/h1-2,4,7-11,19,21H,3,5-6,12-17H2 KBEZSZDCVSAXFP-UHFFFAOYSA-N 50409488 CHEMBL87026 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9930475 163358512 CHEMBL87026 ZINC13471634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152735 Fc1ccc(cc1)C(=O)C1CCN(CC2CC(=O)c3ccccc23)CC1 InChI=1S/C22H22FNO2/c23-18-7-5-15(6-8-18)22(26)16-9-11-24(12-10-16)14-17-13-21(25)20-4-2-1-3-19(17)20/h1-8,16-17H,9-14H2 GMDLSAWBJALPNC-UHFFFAOYSA-N 50409499 CHEMBL109548 D(2) dopamine receptor Rattus norvegicus 1047 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409499&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44326982 163358523 CHEMBL109548 ZINC12356165 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152741 COc1ccccc1N1CCN(CC2Cc3sccc3C(=O)C2)CC1 InChI=1S/C20H24N2O2S/c1-24-19-5-3-2-4-17(19)22-9-7-21(8-10-22)14-15-12-18(23)16-6-11-25-20(16)13-15/h2-6,11,15H,7-10,12-14H2,1H3 GFOUFGCPXBMGCF-UHFFFAOYSA-N 50409504 CHEMBL109528 D(2) dopamine receptor Rattus norvegicus 324 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409504&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10473483 163358528 CHEMBL109528 ZINC13471651 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152742 Fc1ccc(cc1)C(=O)C1CCN(CCC2CCc3ccccc3C2=O)CC1 InChI=1S/C24H26FNO2/c25-21-9-7-18(8-10-21)23(27)20-12-15-26(16-13-20)14-11-19-6-5-17-3-1-2-4-22(17)24(19)28/h1-4,7-10,19-20H,5-6,11-16H2 CWYWUEUVHLRQJP-UHFFFAOYSA-N 50409509 CHEMBL87943 D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9886130 163358533 CHEMBL87943 ZINC13471630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152747 Fc1ccc(cc1)C(=O)C1CCN(CCC2Cc3sccc3C2=O)CC1 InChI=1S/C21H22FNO2S/c22-17-3-1-14(2-4-17)20(24)15-5-9-23(10-6-15)11-7-16-13-19-18(21(16)25)8-12-26-19/h1-4,8,12,15-16H,5-7,9-11,13H2 YJKQCYMQSRDUEQ-UHFFFAOYSA-N 50409494 CHEMBL159969 D(2) dopamine receptor Rattus norvegicus 407 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409494&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10022123 163358518 CHEMBL159969 ZINC12356169 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152753 Fc1ccc(cc1)C(=O)CCCN1CCN(CC2CC(=O)c3ccccc3C2)CC1 InChI=1S/C25H29FN2O2/c26-22-9-7-20(8-10-22)24(29)6-3-11-27-12-14-28(15-13-27)18-19-16-21-4-1-2-5-23(21)25(30)17-19/h1-2,4-5,7-10,19H,3,6,11-18H2 WIVGCTVBLDUZMD-UHFFFAOYSA-N 50409493 CHEMBL310734 D(2) dopamine receptor Rattus norvegicus 25 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409493&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10386748 163358517 CHEMBL310734 ZINC22925153 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152755 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152756 Fc1ccc(cc1)C(=O)CCCN1CCN(CCC2CCc3sccc3C2=O)CC1 InChI=1S/C24H29FN2O2S/c25-20-6-3-18(4-7-20)22(28)2-1-11-26-13-15-27(16-14-26)12-9-19-5-8-23-21(24(19)29)10-17-30-23/h3-4,6-7,10,17,19H,1-2,5,8-9,11-16H2 AWPTVVFLXLCOBI-UHFFFAOYSA-N 50409495 CHEMBL111189 D(2) dopamine receptor Rattus norvegicus 224 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409495&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10693836 163358519 CHEMBL111189 ZINC26672579 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152760 COc1ccccc1N1CCN(CCC2CCc3ccccc3C2=O)CC1 InChI=1S/C23H28N2O2/c1-27-22-9-5-4-8-21(22)25-16-14-24(15-17-25)13-12-19-11-10-18-6-2-3-7-20(18)23(19)26/h2-9,19H,10-17H2,1H3 PJOARVZMKMVACL-UHFFFAOYSA-N 50409521 CHEMBL92145 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409521&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10044334 163358545 CHEMBL92145 ZINC12356229 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152765 Fc1ccc(cc1)C(=O)C1CCN(CCC2Cc3ccccc3C2=O)CC1 InChI=1S/C23H24FNO2/c24-20-7-5-16(6-8-20)22(26)17-9-12-25(13-10-17)14-11-19-15-18-3-1-2-4-21(18)23(19)27/h1-8,17,19H,9-15H2 AVNSTIVMFUJDDN-UHFFFAOYSA-N 50409497 CHEMBL87717 D(2) dopamine receptor Rattus norvegicus 71 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9951008 163358521 CHEMBL87717 ZINC12356224 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152766 Fc1ccc(cc1)C(=O)CCCN1CCN(CCC2CCc3ccccc3C2=O)CC1 InChI=1S/C26H31FN2O2/c27-23-11-9-21(10-12-23)25(30)6-3-14-28-16-18-29(19-17-28)15-13-22-8-7-20-4-1-2-5-24(20)26(22)31/h1-2,4-5,9-12,22H,3,6-8,13-19H2 WGYPNYKGDVKOAN-UHFFFAOYSA-N 50409496 CHEMBL96781 D(2) dopamine receptor Rattus norvegicus 91 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409496&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9979654 163358520 CHEMBL96781 ZINC22033040 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152767 Fc1ccc(cc1)C(=O)CCCN1CCN(CC2Cc3sccc3C(=O)C2)CC1 InChI=1S/C23H27FN2O2S/c24-19-5-3-18(4-6-19)21(27)2-1-8-25-9-11-26(12-10-25)16-17-14-22(28)20-7-13-29-23(20)15-17/h3-7,13,17H,1-2,8-12,14-16H2 LGAZBHZJAUYBTQ-UHFFFAOYSA-N 50409502 CHEMBL325253 D(2) dopamine receptor Rattus norvegicus 269 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409502&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10645469 163358526 CHEMBL325253 ZINC22925183 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152770 Fc1ccc(cc1)C(=O)C1CCN(CCC2CCc3ccsc3C2=O)CC1 InChI=1S/C22H24FNO2S/c23-19-5-3-15(4-6-19)20(25)17-8-12-24(13-9-17)11-7-16-1-2-18-10-14-27-22(18)21(16)26/h3-6,10,14,16-17H,1-2,7-9,11-13H2 OJZIUDCESMPEPL-UHFFFAOYSA-N 50409520 CHEMBL321682 D(2) dopamine receptor Rattus norvegicus 174 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44327153 163358544 CHEMBL321682 ZINC13471678 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152775 COc1ccccc1N1CCN(CC2CC(=O)c3ccccc3C2)CC1 InChI=1S/C22H26N2O2/c1-26-22-9-5-4-8-20(22)24-12-10-23(11-13-24)16-17-14-18-6-2-3-7-19(18)21(25)15-17/h2-9,17H,10-16H2,1H3 UMEYBQLIJXNFOT-UHFFFAOYSA-N 50409503 CHEMBL310153 D(2) dopamine receptor Rattus norvegicus 6.5 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15021875 163358527 CHEMBL310153 ZINC13471608 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150562 Cc1cc2nc(N3CCNCC3)n(Cc3ccccc3)c2cc1C InChI=1S/C20H24N4/c1-15-12-18-19(13-16(15)2)24(14-17-6-4-3-5-7-17)20(22-18)23-10-8-21-9-11-23/h3-7,12-13,21H,8-11,14H2,1-2H3 HBJFQCBYCFIBOI-UHFFFAOYSA-N 50459424 CHEMBL64880 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50459424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50459424&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10734486 433926689 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51150574 Clc1ccc2n(Cc3ccccc3)c(nc2c1)N1CCNCC1 InChI=1S/C18H19ClN4/c19-15-6-7-17-16(12-15)21-18(22-10-8-20-9-11-22)23(17)13-14-4-2-1-3-5-14/h1-7,12,20H,8-11,13H2 RDAXAGXJSCEYLT-UHFFFAOYSA-N 50471510 CHEMBL294083 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm960442e 10.7270/Q2P271TB 9046349 Orjales, A; Mosquera, R; Labeaga, L; Rodes, R FAES, S.A. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10806082 433938775 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152784 Fc1ccc(cc1)C(=O)C1CCN(CC2Cc3sccc3C(=O)C2)CC1 InChI=1S/C21H22FNO2S/c22-17-3-1-15(2-4-17)21(25)16-5-8-23(9-6-16)13-14-11-19(24)18-7-10-26-20(18)12-14/h1-4,7,10,14,16H,5-6,8-9,11-13H2 KOJOODSKKCAJQB-UHFFFAOYSA-N 50409506 CHEMBL111393 D(2) dopamine receptor Rattus norvegicus 316 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409506&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44327167 163358530 CHEMBL111393 ZINC12356173 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152785 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 263 ChEMBL 10.1021/jm981094e 10.7270/Q2BG2RR8 10425088 Raviña, E; Negreira, J; Cid, J; Masaguer, CF; Rosa, E; Rivas, ME; Fontenla, JA; Loza, MI; Tristán, H; Cadavid, MI; Sanz, F; Lozoya, E; Carotti, A; Carrieri, A Universidad de Santiago http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152800 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus <6.00 ChEMBL 10.1021/jm9910324 10.7270/Q26Q210W 10425105 Quaglia, W; Pigini, M; Piergentili, A; Giannella, M; Marucci, G; Poggesi, E; Leonardi, A; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152805 COc1cccc(OC)c1OCCNCC1C(Cc2ccccc2C1=O)c1ccccc1 InChI=1S/C27H29NO4/c1-30-24-13-8-14-25(31-2)27(24)32-16-15-28-18-23-22(19-9-4-3-5-10-19)17-20-11-6-7-12-21(20)26(23)29/h3-14,22-23,28H,15-18H2,1-2H3 PDAVXRWJDNCAQA-UHFFFAOYSA-N 50472328 CHEMBL330599 D(2) dopamine receptor Rattus norvegicus <6.00 ChEMBL 10.1021/jm9910324 10.7270/Q26Q210W 10425105 Quaglia, W; Pigini, M; Piergentili, A; Giannella, M; Marucci, G; Poggesi, E; Leonardi, A; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472328&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331544 433939593 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152808 COc1cccc(OC)c1OCCNCC1C(Oc2ccccc2C1=O)c1ccccc1 InChI=1S/C26H27NO5/c1-29-22-13-8-14-23(30-2)26(22)31-16-15-27-17-20-24(28)19-11-6-7-12-21(19)32-25(20)18-9-4-3-5-10-18/h3-14,20,25,27H,15-17H2,1-2H3 PUAAUDBUJSSOLX-UHFFFAOYSA-N 50472330 CHEMBL99489 D(2) dopamine receptor Rattus norvegicus <6.00 ChEMBL 10.1021/jm9910324 10.7270/Q26Q210W 10425105 Quaglia, W; Pigini, M; Piergentili, A; Giannella, M; Marucci, G; Poggesi, E; Leonardi, A; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14743458 433939595 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152814 COc1cccc(OC)c1OCCNCC1COc2ccccc2O1 InChI=1S/C19H23NO5/c1-21-17-8-5-9-18(22-2)19(17)23-11-10-20-12-14-13-24-15-6-3-4-7-16(15)25-14/h3-9,14,20H,10-13H2,1-2H3 GYSZUJHYXCZAKI-UHFFFAOYSA-N 69602 2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride::CHEMBL25554::MLS000859914::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride::SMR000326775::WB-4101::WB-4101 hydrochloride::cid_11957505 D(2) dopamine receptor Rattus norvegicus 6.91 ChEMBL 10.1021/jm9910324 10.7270/Q26Q210W 10425105 Quaglia, W; Pigini, M; Piergentili, A; Giannella, M; Marucci, G; Poggesi, E; Leonardi, A; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5685 252647768 64094 CHEMBL25554 ZINC02169424 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152833 COc1cccc(OC)c1OCCNCC1Oc2ccccc2CC1c1ccccc1 InChI=1S/C26H29NO4/c1-28-23-13-8-14-24(29-2)26(23)30-16-15-27-18-25-21(19-9-4-3-5-10-19)17-20-11-6-7-12-22(20)31-25/h3-14,21,25,27H,15-18H2,1-2H3 YNZFNGNFBKOQRH-UHFFFAOYSA-N 50472327 CHEMBL318257 D(2) dopamine receptor Rattus norvegicus <6.00 ChEMBL 10.1021/jm9910324 10.7270/Q26Q210W 10425105 Quaglia, W; Pigini, M; Piergentili, A; Giannella, M; Marucci, G; Poggesi, E; Leonardi, A; Melchiorre, C University of Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44331432 433939592 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152876 O[C@@H]1[C@@H](CC[C@H]1Oc1ccccc1)NC[C@@H]1COc2ccccc2O1 InChI=1S/C20H23NO4/c22-20-16(10-11-19(20)24-14-6-2-1-3-7-14)21-12-15-13-23-17-8-4-5-9-18(17)25-15/h1-9,15-16,19-22H,10-13H2/t15-,16-,19-,20-/m1/s1 STBHTUOPFMOXDX-XNFNUYLZSA-N 50472354 CHEMBL134428 D(2) dopamine receptor Rattus norvegicus 6166 ChEMBL 10.1021/jm991065j 10.7270/Q2TF012V 10514291 Bolognesi, ML; Budriesi, R; Cavalli, A; Chiarini, A; Gotti, R; Leonardi, A; Minarini, A; Poggesi, E; Recanatini, M; Rosini, M; Tumiatti, V; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472354&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10688604 433939619 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152878 O[C@@H]1[C@@H](CC[C@H]1Oc1ccccc1)NC[C@H]1COc2ccccc2O1 InChI=1S/C20H23NO4/c22-20-16(10-11-19(20)24-14-6-2-1-3-7-14)21-12-15-13-23-17-8-4-5-9-18(17)25-15/h1-9,15-16,19-22H,10-13H2/t15-,16+,19+,20+/m0/s1 STBHTUOPFMOXDX-LNKGRISISA-N 50472353 CHEMBL135973 D(2) dopamine receptor Rattus norvegicus 2399 ChEMBL 10.1021/jm991065j 10.7270/Q2TF012V 10514291 Bolognesi, ML; Budriesi, R; Cavalli, A; Chiarini, A; Gotti, R; Leonardi, A; Minarini, A; Poggesi, E; Recanatini, M; Rosini, M; Tumiatti, V; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472353&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10617200 433939618 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152887 O[C@H]1[C@H](CC[C@@H]1Oc1ccccc1)NC[C@@H]1COc2ccccc2O1 InChI=1S/C20H23NO4/c22-20-16(10-11-19(20)24-14-6-2-1-3-7-14)21-12-15-13-23-17-8-4-5-9-18(17)25-15/h1-9,15-16,19-22H,10-13H2/t15-,16+,19+,20+/m1/s1 STBHTUOPFMOXDX-LPWQTFTOSA-N 50472358 CHEMBL132378 D(2) dopamine receptor Rattus norvegicus 1122 ChEMBL 10.1021/jm991065j 10.7270/Q2TF012V 10514291 Bolognesi, ML; Budriesi, R; Cavalli, A; Chiarini, A; Gotti, R; Leonardi, A; Minarini, A; Poggesi, E; Recanatini, M; Rosini, M; Tumiatti, V; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472358&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10065903 433939623 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152903 O[C@H]1[C@H](CC[C@@H]1Oc1ccccc1)NC[C@H]1COc2ccccc2O1 InChI=1S/C20H23NO4/c22-20-16(10-11-19(20)24-14-6-2-1-3-7-14)21-12-15-13-23-17-8-4-5-9-18(17)25-15/h1-9,15-16,19-22H,10-13H2/t15-,16-,19-,20-/m0/s1 STBHTUOPFMOXDX-FVCZOJIISA-N 50472355 CHEMBL135974 D(2) dopamine receptor Rattus norvegicus 2399 ChEMBL 10.1021/jm991065j 10.7270/Q2TF012V 10514291 Bolognesi, ML; Budriesi, R; Cavalli, A; Chiarini, A; Gotti, R; Leonardi, A; Minarini, A; Poggesi, E; Recanatini, M; Rosini, M; Tumiatti, V; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10640982 433939620 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152908 CCCN(CCC)C1CCc2cccc(O)c2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 ASXGJMSKWNBENU-UHFFFAOYSA-N 21393 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::8-Hydroxy-2-(di-n-propylamino)tetralin::8-OH-DPAT::8-OH-DPAT,(+)::8-OH-DPAT,(-)::8-hydroxy-N,N-dipropylaminotetralin::CHEMBL1788118::CHEMBL505765::CHEMBL56::DPAT::US10562853, Compound 8-OH-DPAT::[3H]-8-OH-DPAT::cid_1220 D(2) dopamine receptor Rattus norvegicus <1000 ChEMBL 10.1021/jm991065j 10.7270/Q2TF012V 10514291 Bolognesi, ML; Budriesi, R; Cavalli, A; Chiarini, A; Gotti, R; Leonardi, A; Minarini, A; Poggesi, E; Recanatini, M; Rosini, M; Tumiatti, V; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21393&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1220 49689465 73364 CHEMBL1788118CHEMBL505765CHEMBL56 31 ZINC03870313 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152909 COc1cccc(OC)c1OCCNCC1COc2ccccc2O1 InChI=1S/C19H23NO5/c1-21-17-8-5-9-18(22-2)19(17)23-11-10-20-12-14-13-24-15-6-3-4-7-16(15)25-14/h3-9,14,20H,10-13H2,1-2H3 GYSZUJHYXCZAKI-UHFFFAOYSA-N 69602 2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dimethoxyphenoxy)ethyl]amine;hydrochloride::CHEMBL25554::MLS000859914::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-2-(2,6-dimethoxyphenoxy)ethanamine;hydrochloride::SMR000326775::WB-4101::WB-4101 hydrochloride::cid_11957505 D(2) dopamine receptor Rattus norvegicus 123 ChEMBL 10.1021/jm991065j 10.7270/Q2TF012V 10514291 Bolognesi, ML; Budriesi, R; Cavalli, A; Chiarini, A; Gotti, R; Leonardi, A; Minarini, A; Poggesi, E; Recanatini, M; Rosini, M; Tumiatti, V; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69602&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5685 252647768 64094 CHEMBL25554 ZINC02169424 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51152921 COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3 AYYCFGDXLUPJAQ-UHFFFAOYSA-N 50026917 8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-azaspiro[4.5]decane-7,9-dione::8-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione::8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione::8-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decane-7,9-dione(BMY-7378)::BMY 7378::BMY-7378::CHEMBL1256934::CHEMBL13647::CHEMBL543741 D(2) dopamine receptor Rattus norvegicus 49 ChEMBL 10.1021/jm991065j 10.7270/Q2TF012V 10514291 Bolognesi, ML; Budriesi, R; Cavalli, A; Chiarini, A; Gotti, R; Leonardi, A; Minarini, A; Poggesi, E; Recanatini, M; Rosini, M; Tumiatti, V; Melchiorre, C University of Bologna http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026917&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2419 103936501 CHEMBL543741CHEMBL1256934CHEMBL13647 9 ZINC53064442 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51147770 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 5.0 ChEMBL 10.1021/jm00042a009 10.7270/Q25H7K01 7914540 Fontenla, JA; Osuna, J; Rosa, E; Castro, ME; G-Ferreiro, T; Loza-García, I; Calleja, JM; Sanz, F; Rodríguez, J; Raviña, E University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51147771 Fc1ccc(cc1)C(=O)C1CCN(CCC2Cc3ccccc3C2=O)CC1 InChI=1S/C23H24FNO2/c24-20-7-5-16(6-8-20)22(26)17-9-12-25(13-10-17)14-11-19-15-18-3-1-2-4-21(18)23(19)27/h1-8,17,19H,9-15H2 AVNSTIVMFUJDDN-UHFFFAOYSA-N 50409497 CHEMBL87717 D(2) dopamine receptor Rattus norvegicus 71 ChEMBL 10.1021/jm00042a009 10.7270/Q25H7K01 7914540 Fontenla, JA; Osuna, J; Rosa, E; Castro, ME; G-Ferreiro, T; Loza-García, I; Calleja, JM; Sanz, F; Rodríguez, J; Raviña, E University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9951008 163358521 CHEMBL87717 ZINC12356224 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51147773 Fc1ccc(cc1)C(=O)C1CCN(CCC2Cc3cc(F)ccc3C2=O)CC1 InChI=1S/C23H23F2NO2/c24-19-3-1-15(2-4-19)22(27)16-7-10-26(11-8-16)12-9-17-13-18-14-20(25)5-6-21(18)23(17)28/h1-6,14,16-17H,7-13H2 OWXLOVODAGXFLI-UHFFFAOYSA-N 50409514 CHEMBL87458 D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1021/jm00042a009 10.7270/Q25H7K01 7914540 Fontenla, JA; Osuna, J; Rosa, E; Castro, ME; G-Ferreiro, T; Loza-García, I; Calleja, JM; Sanz, F; Rodríguez, J; Raviña, E University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9951964 163358538 CHEMBL87458 ZINC13471626 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51147774 Fc1ccc(cc1)C(=O)C1CCN(CCC2CCCc3ccccc3C2=O)CC1 InChI=1S/C25H28FNO2/c26-22-10-8-20(9-11-22)24(28)21-13-16-27(17-14-21)15-12-19-6-3-5-18-4-1-2-7-23(18)25(19)29/h1-2,4,7-11,19,21H,3,5-6,12-17H2 KBEZSZDCVSAXFP-UHFFFAOYSA-N 50409488 CHEMBL87026 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/jm00042a009 10.7270/Q25H7K01 7914540 Fontenla, JA; Osuna, J; Rosa, E; Castro, ME; G-Ferreiro, T; Loza-García, I; Calleja, JM; Sanz, F; Rodríguez, J; Raviña, E University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409488&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9930475 163358512 CHEMBL87026 ZINC13471634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51147776 Fc1ccc(cc1)C(=O)C1CCN(CCC2CCc3ccccc3C2=O)CC1 InChI=1S/C24H26FNO2/c25-21-9-7-18(8-10-21)23(27)20-12-15-26(16-13-20)14-11-19-6-5-17-3-1-2-4-22(17)24(19)28/h1-4,7-10,19-20H,5-6,11-16H2 CWYWUEUVHLRQJP-UHFFFAOYSA-N 50409509 CHEMBL87943 D(2) dopamine receptor Rattus norvegicus 48 ChEMBL 10.1021/jm00042a009 10.7270/Q25H7K01 7914540 Fontenla, JA; Osuna, J; Rosa, E; Castro, ME; G-Ferreiro, T; Loza-García, I; Calleja, JM; Sanz, F; Rodríguez, J; Raviña, E University of Santiago de Compostela http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9886130 163358533 CHEMBL87943 ZINC13471630 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146118 Cc1cccc(N2CCN(CCC(=O)c3cc4CCCN5C(=O)CCc(c3)c45)CC2)c1C InChI=1S/C27H33N3O2/c1-19-5-3-7-24(20(19)2)29-15-13-28(14-16-29)12-10-25(31)23-17-21-6-4-11-30-26(32)9-8-22(18-23)27(21)30/h3,5,7,17-18H,4,6,8-16H2,1-2H3 RZMKVGLUNCALDS-UHFFFAOYSA-N 50469498 CHEMBL4286782 D(2) dopamine receptor Rattus norvegicus 1853 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469498&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103399 433936763 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51149910 CCOC(=O)c1[nH]c2ccc(CCN3C(=O)CNC3=O)cc2c1CCN(C)C InChI=1S/C20H26N4O4/c1-4-28-19(26)18-14(8-9-23(2)3)15-11-13(5-6-16(15)22-18)7-10-24-17(25)12-21-20(24)27/h5-6,11,22H,4,7-10,12H2,1-3H3,(H,21,27) VUTJSJLMAPBIJY-UHFFFAOYSA-N 50471285 CHEMBL76480 D(2) dopamine receptor Rattus norvegicus 10715 ChEMBL 10.1021/jm9605849 10.7270/Q2QZ2DN1 9240350 Moloney, GP; Robertson, AD; Martin, GR; MacLennan, S; Mathews, N; Dodsworth, S; Sang, PY; Knight, C; Glen, R Monash University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50471285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50471285&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10738913 433938550 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146129 O=C(CCN1CCN(CC1)c1ncccn1)c1cc2CCCN3C(=O)CCc(c1)c23 InChI=1S/C23H27N5O2/c29-20(6-10-26-11-13-27(14-12-26)23-24-7-2-8-25-23)19-15-17-3-1-9-28-21(30)5-4-18(16-19)22(17)28/h2,7-8,15-16H,1,3-6,9-14H2 XMAJZXPBSHQXFR-UHFFFAOYSA-N 50469499 CHEMBL4295119 D(2) dopamine receptor Rattus norvegicus >2000 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469499&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103402 433936764 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146130 Cc1cccc(N2CCN(CCCC(=O)c3cc4CCCN5C(=O)CCc(c3)c45)CC2)c1C InChI=1S/C28H35N3O2/c1-20-6-3-8-25(21(20)2)30-16-14-29(15-17-30)12-5-9-26(32)24-18-22-7-4-13-31-27(33)11-10-23(19-24)28(22)31/h3,6,8,18-19H,4-5,7,9-17H2,1-2H3 HZPIGJFPWFUMPP-UHFFFAOYSA-N 50469505 CHEMBL4290422 D(2) dopamine receptor Rattus norvegicus 185 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469505&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103263 433936770 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146131 OC(CCN1CCC(CC1)c1noc2cc(F)ccc12)c1cc2CCCN3C(=O)CCc(c1)c23 InChI=1S/C27H30FN3O3/c28-21-4-5-22-24(16-21)34-29-26(22)17-7-11-30(12-8-17)13-9-23(32)20-14-18-2-1-10-31-25(33)6-3-19(15-20)27(18)31/h4-5,14-17,23,32H,1-3,6-13H2 AQABOYBLRCLUDJ-UHFFFAOYSA-N 50469506 CHEMBL4288766 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469506&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103324 433936771 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153307 O=C1Nc2cccc3CCCC1(CCCCN1CCC(=CC1)c1ccccc1)c23 InChI=1S/C26H30N2O/c29-25-26(16-7-11-22-10-6-12-23(27-25)24(22)26)15-4-5-17-28-18-13-21(14-19-28)20-8-2-1-3-9-20/h1-3,6,8-10,12-13H,4-5,7,11,14-19H2,(H,27,29) JBQOYPLKTTXLSQ-UHFFFAOYSA-N 50116963 2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-2a,3,4,5-tetrahydrobenzo[cd]indol-2(1H)-one::2a-[4-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-butyl]-2a,3,4,5-tetrahydro-1H-benzo[cd]indol-2-one::CHEMBL69257 D(2) dopamine receptor Rattus norvegicus 105 ChEMBL 10.1021/jm980519u 10.7270/Q2X63QPV 10052959 Kikuchi, C; Nagaso, H; Hiranuma, T; Koyama, M Meiji Seika Kaisha Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116963&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9843179 104010589 CHEMBL69257 ZINC03985556 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146189 Fc1ccc2c(noc2c1)C1CCN(CCCC(=O)c2cc3CCC(=O)N4CCc(c34)c2F)CC1 InChI=1S/C27H27F2N3O3/c28-18-4-5-19-23(15-18)35-30-26(19)16-7-11-31(12-8-16)10-1-2-22(33)21-14-17-3-6-24(34)32-13-9-20(25(21)29)27(17)32/h4-5,14-16H,1-3,6-13H2 RAHZYUSXDZLMAQ-UHFFFAOYSA-N 50469502 CHEMBL4276702 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469502&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103323 433936767 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146195 O=C(CCN1CCN(CC1)c1nsc2ccccc12)c1cc2CCCN3C(=O)CCc(c1)c23 InChI=1S/C26H28N4O2S/c31-22(20-16-18-4-3-10-30-24(32)8-7-19(17-20)25(18)30)9-11-28-12-14-29(15-13-28)26-21-5-1-2-6-23(21)33-27-26/h1-2,5-6,16-17H,3-4,7-15H2 IMIYBLLQQOUBRO-UHFFFAOYSA-N 50469527 CHEMBL4289001 D(2) dopamine receptor Rattus norvegicus 182 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469527&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103258 433936792 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146196 CC1CC(=O)N2CCCc3cc(CCCCN4CCC(CC4)c4noc5cc(F)ccc45)cc1c23 InChI=1S/C29H34FN3O2/c1-19-15-27(34)33-12-4-6-22-16-20(17-25(19)29(22)33)5-2-3-11-32-13-9-21(10-14-32)28-24-8-7-23(30)18-26(24)35-31-28/h7-8,16-19,21H,2-6,9-15H2,1H3 MWGXDVJEZYRXAG-UHFFFAOYSA-N 50469528 CHEMBL4280873 D(2) dopamine receptor Rattus norvegicus 86 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469528 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469528&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103162 433936793 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146197 Clc1cccc(N2CCN(CCCC(=O)c3cc4CCN5c4c(CCC5=O)c3)CC2)c1Cl InChI=1S/C25H27Cl2N3O2/c26-20-3-1-4-21(24(20)27)29-13-11-28(12-14-29)9-2-5-22(31)19-15-17-6-7-23(32)30-10-8-18(16-19)25(17)30/h1,3-4,15-16H,2,5-14H2 SMCWUBAJDPUTDT-UHFFFAOYSA-N 50469511 CHEMBL4292889 D(2) dopamine receptor Rattus norvegicus 104 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469511&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103171 433936776 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146198 Fc1ccc2c(noc2c1)C1CCN(CCCCc2cc3CCN4c3c(CCC4=O)c2)CC1 InChI=1S/C27H30FN3O2/c28-22-5-6-23-24(17-22)33-29-26(23)19-8-12-30(13-9-19)11-2-1-3-18-15-20-4-7-25(32)31-14-10-21(16-18)27(20)31/h5-6,15-17,19H,1-4,7-14H2 UIXQJBAAWGMZKH-UHFFFAOYSA-N 50469524 CHEMBL4283548 D(2) dopamine receptor Rattus norvegicus 9.9 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469524&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103313 433936789 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146201 COc1ccccc1N1CCN(CCC(=O)c2cc3CCCN4C(=O)CCc(c2)c34)CC1 InChI=1S/C26H31N3O3/c1-32-24-7-3-2-6-22(24)28-15-13-27(14-16-28)12-10-23(30)21-17-19-5-4-11-29-25(31)9-8-20(18-21)26(19)29/h2-3,6-7,17-18H,4-5,8-16H2,1H3 PEGZPMUPTRWLEP-UHFFFAOYSA-N 50469529 CHEMBL4294685 D(2) dopamine receptor Rattus norvegicus >2000 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469529&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103405 433936794 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146221 Clc1ccc(cc1)N1CCN(CCC(=O)c2cc3CCCN4C(=O)CCc(c2)c34)CC1 InChI=1S/C25H28ClN3O2/c26-21-4-6-22(7-5-21)28-14-12-27(13-15-28)11-9-23(30)20-16-18-2-1-10-29-24(31)8-3-19(17-20)25(18)29/h4-7,16-17H,1-3,8-15H2 JGMBAFJTUVFCTA-UHFFFAOYSA-N 50469509 CHEMBL4293833 D(2) dopamine receptor Rattus norvegicus >2000 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469509&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103398 433936774 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146222 Clc1cccc(N2CCN(CCC(=O)c3cc4CCCN5C(=O)CCc(c3)c45)CC2)c1Cl InChI=1S/C25H27Cl2N3O2/c26-20-4-1-5-21(24(20)27)29-13-11-28(12-14-29)10-8-22(31)19-15-17-3-2-9-30-23(32)7-6-18(16-19)25(17)30/h1,4-5,15-16H,2-3,6-14H2 FOEQJLVTQLQGHR-UHFFFAOYSA-N 50469535 CHEMBL4287810 D(2) dopamine receptor Rattus norvegicus 1218 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469535&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103406 433936800 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146223 Fc1ccc2c(noc2c1)C1CCN(CCC(=O)c2cc3CCCN4C(=O)CCc(c2)c34)CC1 InChI=1S/C27H28FN3O3/c28-21-4-5-22-24(16-21)34-29-26(22)17-7-11-30(12-8-17)13-9-23(32)20-14-18-2-1-10-31-25(33)6-3-19(15-20)27(18)31/h4-5,14-17H,1-3,6-13H2 GBQJCMTWZANREL-UHFFFAOYSA-N 50469507 CHEMBL4287008 D(2) dopamine receptor Rattus norvegicus 58 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469507&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103257 433936772 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146224 Clc1cccc(N2CCN(CCCC(=O)c3cc4CCCN5C(=O)CCc(c3)c45)CC2)c1Cl InChI=1S/C26H29Cl2N3O2/c27-21-5-1-6-22(25(21)28)30-14-12-29(13-15-30)10-3-7-23(32)20-16-18-4-2-11-31-24(33)9-8-19(17-20)26(18)31/h1,5-6,16-17H,2-4,7-15H2 DJEXENNUHMGVHT-UHFFFAOYSA-N 50469530 CHEMBL4293347 D(2) dopamine receptor Rattus norvegicus 283 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469530&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103261 433936795 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146225 O=C(CCCN1CCN(CC1)c1nsc2ccccc12)c1cc2CCCN3C(=O)CCc(c1)c23 InChI=1S/C27H30N4O2S/c32-23(21-17-19-5-3-12-31-25(33)10-9-20(18-21)26(19)31)7-4-11-29-13-15-30(16-14-29)27-22-6-1-2-8-24(22)34-28-27/h1-2,6,8,17-18H,3-5,7,9-16H2 HAEUVCGDLGYYJI-UHFFFAOYSA-N 50469536 CHEMBL4288971 D(2) dopamine receptor Rattus norvegicus 91 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469536&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103259 433936801 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146226 Fc1ccc2c(noc2c1)C1CCN(CCCCC(=O)c2cc3CCCN4C(=O)CCc(c2)c34)CC1 InChI=1S/C29H32FN3O3/c30-23-7-8-24-26(18-23)36-31-28(24)19-10-14-32(15-11-19)12-2-1-5-25(34)22-16-20-4-3-13-33-27(35)9-6-21(17-22)29(20)33/h7-8,16-19H,1-6,9-15H2 BVYIKBKMXWQFAK-UHFFFAOYSA-N 50469520 CHEMBL4293659 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469520&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103320 433936785 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146227 Fc1ccc2c(noc2c1)C1CCN(CC(=O)c2cc3CCCN4C(=O)CCc(c2)c34)CC1 InChI=1S/C26H26FN3O3/c27-20-4-5-21-23(14-20)33-28-25(21)16-7-10-29(11-8-16)15-22(31)19-12-17-2-1-9-30-24(32)6-3-18(13-19)26(17)30/h4-5,12-14,16H,1-3,6-11,15H2 FDSBLWKKDJSSNF-UHFFFAOYSA-N 50469537 CHEMBL4282378 D(2) dopamine receptor Rattus norvegicus 900 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469537&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103256 433936802 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146228 Clc1cccc(N2CCN(CCCc3cc4CCCN5C(=O)CCc(c3)c45)CC2)c1Cl InChI=1S/C25H29Cl2N3O/c26-21-6-1-7-22(24(21)27)29-14-12-28(13-15-29)10-2-4-18-16-19-5-3-11-30-23(31)9-8-20(17-18)25(19)30/h1,6-7,16-17H,2-5,8-15H2 OGYOGAQPTWQGQE-UHFFFAOYSA-N 50469518 CHEMBL4278918 D(2) dopamine receptor Rattus norvegicus 582 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469518&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103401 433936783 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146229 O=C1CCc2cc(CCCCN3CCN(CC3)c3nsc4ccccc34)cc3CCCN1c23 InChI=1S/C27H32N4OS/c32-25-11-10-22-19-20(18-21-7-5-13-31(25)26(21)22)6-3-4-12-29-14-16-30(17-15-29)27-23-8-1-2-9-24(23)33-28-27/h1-2,8-9,18-19H,3-7,10-17H2 NTKMLVDVAOLBNO-UHFFFAOYSA-N 50469501 CHEMBL4288419 D(2) dopamine receptor Rattus norvegicus 154 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469501&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103260 433936766 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146230 Fc1ccc2c(noc2c1)C1CCN(CCCCc2cc3CCCN4C(=O)CCc(c2)c34)CC1 InChI=1S/C28H32FN3O2/c29-23-7-8-24-25(18-23)34-30-27(24)20-10-14-31(15-11-20)12-2-1-4-19-16-21-5-3-13-32-26(33)9-6-22(17-19)28(21)32/h7-8,16-18,20H,1-6,9-15H2 BGMZWQCMFIMJGX-UHFFFAOYSA-N 50469512 CHEMBL4283488 D(2) dopamine receptor Rattus norvegicus 74 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469512&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103325 433936777 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146231 Cc1cccc(N2CCN(CCC(=O)c3cc4CCN5c4c(CCC5=O)c3)CC2)c1C InChI=1S/C26H31N3O2/c1-18-4-3-5-23(19(18)2)28-14-12-27(13-15-28)10-9-24(30)22-16-20-6-7-25(31)29-11-8-21(17-22)26(20)29/h3-5,16-17H,6-15H2,1-2H3 XNRHBZXLFAHYIW-UHFFFAOYSA-N 50469521 CHEMBL4276681 D(2) dopamine receptor Rattus norvegicus 189 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469521&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103172 433936786 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146232 Fc1cc(ccc1N1CCN(CCC(=O)c2cc3CCN4c3c(CCC4=O)c2)CC1)C#N InChI=1S/C25H25FN4O2/c26-21-13-17(16-27)1-3-22(21)29-11-9-28(10-12-29)7-6-23(31)20-14-18-2-4-24(32)30-8-5-19(15-20)25(18)30/h1,3,13-15H,2,4-12H2 UFEGTTKLNBYQCG-UHFFFAOYSA-N 50469522 CHEMBL4291828 D(2) dopamine receptor Rattus norvegicus 574 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469522&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103169 433936787 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146233 O=C(CCN1CCN(CC1)c1nsc2ccccc12)c1cc2CCN3c2c(CCC3=O)c1 InChI=1S/C25H26N4O2S/c30-21(19-15-17-5-6-23(31)29-10-7-18(16-19)24(17)29)8-9-27-11-13-28(14-12-27)25-20-3-1-2-4-22(20)32-26-25/h1-4,15-16H,5-14H2 QAIGRPXNBZSXKS-UHFFFAOYSA-N 50469534 CHEMBL4277770 D(2) dopamine receptor Rattus norvegicus 89 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469534&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103168 433936799 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146234 O=C(CCCN1CCN(CC1)c1nsc2ccccc12)c1cc2CCN3c2c(CCC3=O)c1 InChI=1S/C26H28N4O2S/c31-22(20-16-18-7-8-24(32)30-11-9-19(17-20)25(18)30)5-3-10-28-12-14-29(15-13-28)26-21-4-1-2-6-23(21)33-27-26/h1-2,4,6,16-17H,3,5,7-15H2 IHHRRXJIAPKDJR-UHFFFAOYSA-N 50469523 CHEMBL4285041 D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469523&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103362 433936788 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146235 Fc1ccc2c(noc2c1)C1CCN(CCCC(=O)c2cc3CCN4c3c(CCC4=O)c2)CC1 InChI=1S/C27H28FN3O3/c28-21-4-5-22-24(16-21)34-29-26(22)17-7-11-30(12-8-17)10-1-2-23(32)20-14-18-3-6-25(33)31-13-9-19(15-20)27(18)31/h4-5,14-17H,1-3,6-13H2 LFATXWJLBURBCJ-UHFFFAOYSA-N 50469497 CHEMBL4289498 D(2) dopamine receptor Rattus norvegicus 10 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469497&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103161 433936762 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146236 Fc1ccc2c(noc2c1)C1CCN(CCCC(=O)c2cc3CCN4c3c(CCC4=O)c2F)CC1 InChI=1S/C27H27F2N3O3/c28-18-3-4-19-23(15-18)35-30-26(19)16-7-11-31(12-8-16)10-1-2-22(33)21-14-17-9-13-32-24(34)6-5-20(25(21)29)27(17)32/h3-4,14-16H,1-2,5-13H2 HRYNNLANCWSUBU-UHFFFAOYSA-N 50469500 CHEMBL4281617 D(2) dopamine receptor Rattus norvegicus 19 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469500&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103321 433936765 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146237 Fc1ccc2c(noc2c1)C1CCN(CCCCCC(=O)c2cc3CCN4c3c(CCC4=O)c2)CC1 InChI=1S/C29H32FN3O3/c30-23-6-7-24-26(18-23)36-31-28(24)19-9-13-32(14-10-19)12-3-1-2-4-25(34)22-16-20-5-8-27(35)33-15-11-21(17-22)29(20)33/h6-7,16-19H,1-5,8-15H2 ICTOAQCFEMKCKY-UHFFFAOYSA-N 50469515 CHEMBL4278627 D(2) dopamine receptor Rattus norvegicus 89 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469515 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469515&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 145979839 433936780 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146238 OC(CCN1CCC(CC1)c1noc2cc(F)ccc12)c1cc2CCN3c2c(CCC3=O)c1 InChI=1S/C26H28FN3O3/c27-20-2-3-21-23(15-20)33-28-25(21)16-5-9-29(10-6-16)11-8-22(31)19-13-17-1-4-24(32)30-12-7-18(14-19)26(17)30/h2-3,13-16,22,31H,1,4-12H2 UMHCMHNLJIHAIA-UHFFFAOYSA-N 50469525 CHEMBL4286906 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469525&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103166 433936790 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146239 OC(CCCCN1CCC(CC1)c1noc2cc(F)ccc12)c1cc2CCN3c2c(CCC3=O)c1 InChI=1S/C28H32FN3O3/c29-22-5-6-23-25(17-22)35-30-27(23)18-8-12-31(13-9-18)11-2-1-3-24(33)21-15-19-4-7-26(34)32-14-10-20(16-21)28(19)32/h5-6,15-18,24,33H,1-4,7-14H2 HRYKMSOBBFZAAT-UHFFFAOYSA-N 50469526 CHEMBL4290311 D(2) dopamine receptor Rattus norvegicus 8.4 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469526&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103315 433936791 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154471 CCCN1CCc2c(Br)ccc3Oc4ccc(OC)cc4CC1c23 InChI=1S/C20H22BrNO2/c1-3-9-22-10-8-15-16(21)5-7-19-20(15)17(22)12-13-11-14(23-2)4-6-18(13)24-19/h4-7,11,17H,3,8-10,12H2,1-2H3 BSWKXFMIYCXSMR-UHFFFAOYSA-N 50473112 CHEMBL349311 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473112&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10691657 433940377 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154473 CCN1CCc2cccc3Oc4ccc(O)cc4CC1c23 InChI=1S/C18H19NO2/c1-2-19-9-8-12-4-3-5-17-18(12)15(19)11-13-10-14(20)6-7-16(13)21-17/h3-7,10,15,20H,2,8-9,11H2,1H3 WDBUJQKFRINDKP-UHFFFAOYSA-N 50202316 1-ethyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-10-ol::CHEMBL154468 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202316&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10660476 104081893 CHEMBL154468 ZINC13805117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154474 CCN1CCc2cc(Br)cc(OC)c2C1Cc1ccccc1O InChI=1S/C19H22BrNO2/c1-3-21-9-8-14-10-15(20)12-18(23-2)19(14)16(21)11-13-6-4-5-7-17(13)22/h4-7,10,12,16,22H,3,8-9,11H2,1-2H3 FIENLMYHKXXOLG-UHFFFAOYSA-N 50473113 CHEMBL422169 D(2) dopamine receptor Rattus norvegicus 2188 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473113&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10738274 433940378 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146249 O=C(CCN1CCN(CC1)c1ccccc1)c1cc2CCCN3C(=O)CCc(c1)c23 InChI=1S/C25H29N3O2/c29-23(10-12-26-13-15-27(16-14-26)22-6-2-1-3-7-22)21-17-19-5-4-11-28-24(30)9-8-20(18-21)25(19)28/h1-3,6-7,17-18H,4-5,8-16H2 VAHYYZOSFBQFIL-UHFFFAOYSA-N 50469532 CHEMBL4279959 D(2) dopamine receptor Rattus norvegicus 1765 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469532&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103311 433936797 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146250 O=C(CCN1CCC(CC1)c1nc2ccccc2s1)c1cc2CCCN3C(=O)CCc(c1)c23 InChI=1S/C27H29N3O2S/c31-23(21-16-19-4-3-12-30-25(32)8-7-20(17-21)26(19)30)11-15-29-13-9-18(10-14-29)27-28-22-5-1-2-6-24(22)33-27/h1-2,5-6,16-18H,3-4,7-15H2 CXRFXYSOZUOQKW-UHFFFAOYSA-N 50469531 CHEMBL4289351 D(2) dopamine receptor Rattus norvegicus 861 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469531&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 145988184 433936796 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146251 Fc1ccc2c(noc2c1)C1CCN(CCCc2cc3CCCN4C(=O)CCc(c2)c34)CC1 InChI=1S/C27H30FN3O2/c28-22-6-7-23-24(17-22)33-29-26(23)19-9-13-30(14-10-19)11-1-3-18-15-20-4-2-12-31-25(32)8-5-21(16-18)27(20)31/h6-7,15-17,19H,1-5,8-14H2 CCFCUIZGGIRPTG-UHFFFAOYSA-N 50469513 CHEMBL4290255 D(2) dopamine receptor Rattus norvegicus 44 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469513&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103312 433936778 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146252 Clc1cccc(N2CCN(CCC(=O)c3cc4CCN5c4c(CCC5=O)c3)CC2)c1Cl InChI=1S/C24H25Cl2N3O2/c25-19-2-1-3-20(23(19)26)28-12-10-27(11-13-28)8-7-21(30)18-14-16-4-5-22(31)29-9-6-17(15-18)24(16)29/h1-3,14-15H,4-13H2 GLVWJJHPBWYCLD-UHFFFAOYSA-N 50469514 CHEMBL4281207 D(2) dopamine receptor Rattus norvegicus 188 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469514&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103173 433936779 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146282 CC1CC(=O)N2CCCc3cc(cc1c23)C(=O)CCCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C29H32FN3O3/c1-18-14-27(35)33-11-2-4-20-15-21(16-24(18)29(20)33)25(34)5-3-10-32-12-8-19(9-13-32)28-23-7-6-22(30)17-26(23)36-31-28/h6-7,15-19H,2-5,8-14H2,1H3 XNLUVKGBRJZXII-UHFFFAOYSA-N 50469519 CHEMBL4285781 D(2) dopamine receptor Rattus norvegicus 62 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469519&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103326 433936784 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146287 Fc1ccc2c(noc2c1)C1CCN(CCCc2cc3CCN4c3c(CCC4=O)c2)CC1 InChI=1S/C26H28FN3O2/c27-21-4-5-22-23(16-21)32-28-25(22)18-7-11-29(12-8-18)10-1-2-17-14-19-3-6-24(31)30-13-9-20(15-17)26(19)30/h4-5,14-16,18H,1-3,6-13H2 VMAHGGSWNXWLAH-UHFFFAOYSA-N 50469533 CHEMBL4279363 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469533&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103165 433936798 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146292 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3.7 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146293 Fc1ccc2c(noc2c1)C1CCN(CCCC(=O)c2cc3CCCN4C(=O)CCc(c2)c34)CC1 InChI=1S/C28H30FN3O3/c29-22-6-7-23-25(17-22)35-30-27(23)18-9-13-31(14-10-18)11-2-4-24(33)21-15-19-3-1-12-32-26(34)8-5-20(16-21)28(19)32/h6-7,15-18H,1-5,8-14H2 XFIZVBIFOVFBPT-UHFFFAOYSA-N 50469508 CHEMBL4284435 D(2) dopamine receptor Rattus norvegicus 18 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469508&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103314 433936773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146294 Clc1cccc(N2CCN(CCCCc3cc4CCCN5C(=O)CCc(c3)c45)CC2)c1Cl InChI=1S/C26H31Cl2N3O/c27-22-7-3-8-23(25(22)28)30-15-13-29(14-16-30)11-2-1-5-19-17-20-6-4-12-31-24(32)10-9-21(18-19)26(20)31/h3,7-8,17-18H,1-2,4-6,9-16H2 JMNANONYFXPEKD-UHFFFAOYSA-N 50469517 CHEMBL4286835 D(2) dopamine receptor Rattus norvegicus 394 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469517&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103262 433936782 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146295 OC(CCCN1CCC(CC1)c1noc2cc(F)ccc12)c1cc2CCCN3C(=O)CCc(c1)c23 InChI=1S/C28H32FN3O3/c29-22-6-7-23-25(17-22)35-30-27(23)18-9-13-31(14-10-18)11-2-4-24(33)21-15-19-3-1-12-32-26(34)8-5-20(16-21)28(19)32/h6-7,15-18,24,33H,1-5,8-14H2 HUQUTKNQWAXHNZ-UHFFFAOYSA-N 50469516 CHEMBL4284621 D(2) dopamine receptor Rattus norvegicus 30 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469516&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103316 433936781 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146296 Fc1ccc2c(noc2c1)C1CCN(CCC(=O)c2cc3CCN4c3c(CCC4=O)c2)CC1 InChI=1S/C26H26FN3O3/c27-20-2-3-21-23(15-20)33-28-25(21)16-5-9-29(10-6-16)11-8-22(31)19-13-17-1-4-24(32)30-12-7-18(14-19)26(17)30/h2-3,13-16H,1,4-12H2 BPGYRASDFSWJJG-UHFFFAOYSA-N 50469496 CHEMBL4288409 D(2) dopamine receptor Rattus norvegicus 20 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469496&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103163 433936761 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146297 Fc1ccc2c(noc2c1)C1CCN(CCCCC(=O)c2cc3CCN4c3c(CCC4=O)c2)CC1 InChI=1S/C28H30FN3O3/c29-22-5-6-23-25(17-22)35-30-27(23)18-8-12-31(13-9-18)11-2-1-3-24(33)21-15-19-4-7-26(34)32-14-10-20(16-21)28(19)32/h5-6,15-18H,1-4,7-14H2 ACOZPXLCYUQMHS-UHFFFAOYSA-N 50469504 CHEMBL4293999 D(2) dopamine receptor Rattus norvegicus 2.9 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469504&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103318 433936769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146298 OC(CCCN1CCC(CC1)c1noc2cc(F)ccc12)c1cc2CCN3c2c(CCC3=O)c1 InChI=1S/C27H30FN3O3/c28-21-4-5-22-24(16-21)34-29-26(22)17-7-11-30(12-8-17)10-1-2-23(32)20-14-18-3-6-25(33)31-13-9-19(15-20)27(18)31/h4-5,14-17,23,32H,1-3,6-13H2 XAWSBCLNNJQTCA-UHFFFAOYSA-N 50469503 CHEMBL4294799 D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469503&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103322 433936768 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153446 CN(C)c1cccc(CNCC2CCN(CC2)C(=O)c2ccc(Cl)c(Cl)c2)n1 InChI=1S/C21H26Cl2N4O/c1-26(2)20-5-3-4-17(25-20)14-24-13-15-8-10-27(11-9-15)21(28)16-6-7-18(22)19(23)12-16/h3-7,12,15,24H,8-11,13-14H2,1-2H3 SCPDBFOEQCPCKE-UHFFFAOYSA-N 50472096 CHEMBL42994 D(2) dopamine receptor Rattus norvegicus 525 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472096&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10550097 433939361 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153458 Clc1ccc(cc1Cl)C(=O)N1CCC(CNCc2cccc(n2)-c2cc[nH]n2)CC1 InChI=1S/C22H23Cl2N5O/c23-18-5-4-16(12-19(18)24)22(30)29-10-7-15(8-11-29)13-25-14-17-2-1-3-20(27-17)21-6-9-26-28-21/h1-6,9,12,15,25H,7-8,10-11,13-14H2,(H,26,28) FOYMTZMTURRROB-UHFFFAOYSA-N 50472064 CHEMBL45101 D(2) dopamine receptor Rattus norvegicus 977 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472064&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10789419 433939329 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153464 CN(C)c1cccc(CNCC2(F)CCN(CC2)C(=O)c2cccc(Cl)c2)n1 InChI=1S/C21H26ClFN4O/c1-26(2)19-8-4-7-18(25-19)14-24-15-21(23)9-11-27(12-10-21)20(28)16-5-3-6-17(22)13-16/h3-8,13,24H,9-12,14-15H2,1-2H3 DQQNXTPQVLYYCG-UHFFFAOYSA-N 50472578 CHEMBL42766 D(2) dopamine receptor Rattus norvegicus 617 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472578&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10549236 433939843 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153465 Clc1ccc(cc1Cl)C(=O)N1CCC(CNCc2cccc(n2)-c2ccco2)CC1 InChI=1S/C23H23Cl2N3O2/c24-19-7-6-17(13-20(19)25)23(29)28-10-8-16(9-11-28)14-26-15-18-3-1-4-21(27-18)22-5-2-12-30-22/h1-7,12-13,16,26H,8-11,14-15H2 KSZMCVDTZBUUIA-UHFFFAOYSA-N 50472112 CHEMBL42294 D(2) dopamine receptor Rattus norvegicus 457 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472112&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10765698 433939377 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153466 CN(C)c1cccc(CNCC2(F)CCN(CC2)C(=O)c2ccc(Cl)c(Cl)c2)n1 InChI=1S/C21H25Cl2FN4O/c1-27(2)19-5-3-4-16(26-19)13-25-14-21(24)8-10-28(11-9-21)20(29)15-6-7-17(22)18(23)12-15/h3-7,12,25H,8-11,13-14H2,1-2H3 FRVJJTAZZDAYNQ-UHFFFAOYSA-N 50472579 CHEMBL46971 D(2) dopamine receptor Rattus norvegicus 331 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472579 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472579&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10789182 433939844 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153469 Clc1ccc(cc1Cl)C(=O)N1CCC(CNCc2cccc(n2)N2CCC2)CC1 InChI=1S/C22H26Cl2N4O/c23-19-6-5-17(13-20(19)24)22(29)28-11-7-16(8-12-28)14-25-15-18-3-1-4-21(26-18)27-9-2-10-27/h1,3-6,13,16,25H,2,7-12,14-15H2 LNIQZQYUYOSMFT-UHFFFAOYSA-N 50472057 CHEMBL298260 D(2) dopamine receptor Rattus norvegicus 603 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472057&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10025854 433939322 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153474 Clc1ccc(cc1Cl)C(=O)N1CCC(CNCc2cccc(n2)-c2nccs2)CC1 InChI=1S/C22H22Cl2N4OS/c23-18-5-4-16(12-19(18)24)22(29)28-9-6-15(7-10-28)13-25-14-17-2-1-3-20(27-17)21-26-8-11-30-21/h1-5,8,11-12,15,25H,6-7,9-10,13-14H2 NTCYZWZXRNJMAE-UHFFFAOYSA-N 50472119 CHEMBL46467 D(2) dopamine receptor Rattus norvegicus 3388 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472119&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10813865 433939384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153481 Clc1ccc(cc1Cl)C(=O)N1CCC(CNCc2cccc(n2)-c2cccs2)CC1 InChI=1S/C23H23Cl2N3OS/c24-19-7-6-17(13-20(19)25)23(29)28-10-8-16(9-11-28)14-26-15-18-3-1-4-21(27-18)22-5-2-12-30-22/h1-7,12-13,16,26H,8-11,14-15H2 CKSMNIPCJNWJND-UHFFFAOYSA-N 50472080 CHEMBL42618 D(2) dopamine receptor Rattus norvegicus 288 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472080&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10575934 433939345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153490 FC1(CNCc2cccc(n2)-c2cnco2)CCN(CC1)C(=O)c1ccc(Cl)c(Cl)c1 InChI=1S/C22H21Cl2FN4O2/c23-17-5-4-15(10-18(17)24)21(30)29-8-6-22(25,7-9-29)13-26-11-16-2-1-3-19(28-16)20-12-27-14-31-20/h1-5,10,12,14,26H,6-9,11,13H2 IWSQYCLFGIYRMU-UHFFFAOYSA-N 50472591 CHEMBL44659 D(2) dopamine receptor Rattus norvegicus 2239 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472591&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10695395 433939856 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153495 FC1(CNCc2cccc(n2)-c2cccs2)CCN(CC1)C(=O)c1ccc(Cl)c(Cl)c1 InChI=1S/C23H22Cl2FN3OS/c24-18-7-6-16(13-19(18)25)22(30)29-10-8-23(26,9-11-29)15-27-14-17-3-1-4-20(28-17)21-5-2-12-31-21/h1-7,12-13,27H,8-11,14-15H2 ADGCARVTPQCUGH-UHFFFAOYSA-N 50472575 CHEMBL288244 D(2) dopamine receptor Rattus norvegicus 457 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472575&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10719425 433939840 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153498 Clc1ccc(cc1Cl)C(=O)N1CCC(CNCc2cccc(n2)-c2cnco2)CC1 InChI=1S/C22H22Cl2N4O2/c23-18-5-4-16(10-19(18)24)22(29)28-8-6-15(7-9-28)11-25-12-17-2-1-3-20(27-17)21-13-26-14-30-21/h1-5,10,13-15,25H,6-9,11-12H2 NXAGLLLVGMCGGH-UHFFFAOYSA-N 50472097 CHEMBL297138 D(2) dopamine receptor Rattus norvegicus 871 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472097&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10411236 433939362 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154475 CCCN1CCc2cccc3Oc4ccc(OC)cc4CC1c23 InChI=1S/C20H23NO2/c1-3-10-21-11-9-14-5-4-6-19-20(14)17(21)13-15-12-16(22-2)7-8-18(15)23-19/h4-8,12,17H,3,9-11,13H2,1-2H3 LJKQCNMRYOFRFG-UHFFFAOYSA-N 50473114 CHEMBL350457 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473114&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10781204 433940379 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154481 CCCN1CCc2cc(O)cc3Oc4ccccc4CC1c23 InChI=1S/C19H21NO2/c1-2-8-20-9-7-14-10-15(21)12-18-19(14)16(20)11-13-5-3-4-6-17(13)22-18/h3-6,10,12,16,21H,2,7-9,11H2,1H3 KAVZPHXMOSLALD-UHFFFAOYSA-N 50202339 1-propyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-5-ol::CHEMBL155066 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10589979 104081916 CHEMBL155066 ZINC13805094 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154482 CCN1CCc2cc(OC)cc(Br)c2C1Cc1ccccc1O InChI=1S/C19H22BrNO2/c1-3-21-9-8-14-10-15(23-2)12-16(20)19(14)17(21)11-13-6-4-5-7-18(13)22/h4-7,10,12,17,22H,3,8-9,11H2,1-2H3 TYEIZCYTFJEVNL-UHFFFAOYSA-N 50473119 CHEMBL347243 D(2) dopamine receptor Rattus norvegicus 3090 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473119&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10809507 433940384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154487 CCN1CCc2cc(O)cc3Oc4ccccc4CC1c23 InChI=1S/C18H19NO2/c1-2-19-8-7-13-9-14(20)11-17-18(13)15(19)10-12-5-3-4-6-16(12)21-17/h3-6,9,11,15,20H,2,7-8,10H2,1H3 KAUFSVBKTMJNMB-UHFFFAOYSA-N 50202302 1-ethyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-5-ol::CHEMBL439639 D(2) dopamine receptor Rattus norvegicus 6457 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202302&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10707972 104081879 CHEMBL439639 ZINC13805089 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154488 COc1cc(Br)c2C(Cc3ccccc3O)N(C)CCc2c1 InChI=1S/C18H20BrNO2/c1-20-8-7-13-9-14(22-2)11-15(19)18(13)16(20)10-12-5-3-4-6-17(12)21/h3-6,9,11,16,21H,7-8,10H2,1-2H3 MKINKQXZCCTYOJ-UHFFFAOYSA-N 50473122 CHEMBL158067 D(2) dopamine receptor Rattus norvegicus 7079 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473122&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10832461 433940387 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154489 CN1CCc2cc(O)cc3Oc4ccccc4CC1c23 InChI=1S/C17H17NO2/c1-18-7-6-12-8-13(19)10-16-17(12)14(18)9-11-4-2-3-5-15(11)20-16/h2-5,8,10,14,19H,6-7,9H2,1H3 BBDMAMMSMIPUOS-UHFFFAOYSA-N 50202296 1-Methyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-5-ol::CHEMBL155208 D(2) dopamine receptor Rattus norvegicus 275 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202296&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10333195 104081873 CHEMBL155208 ZINC13805084 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154490 COc1cc2CCN(C)C3Cc4ccccc4Oc(c1)c23 InChI=1S/C18H19NO2/c1-19-8-7-13-9-14(20-2)11-17-18(13)15(19)10-12-5-3-4-6-16(12)21-17/h3-6,9,11,15H,7-8,10H2,1-2H3 HRTZYXZOCORGOL-UHFFFAOYSA-N 50473123 CHEMBL154948 D(2) dopamine receptor Rattus norvegicus 9333 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473123&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10516949 433940388 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154491 COc1ccc2Oc3cccc4CCN(C)C(Cc2c1)c34 InChI=1S/C18H19NO2/c1-19-9-8-12-4-3-5-17-18(12)15(19)11-13-10-14(20-2)6-7-16(13)21-17/h3-7,10,15H,8-9,11H2,1-2H3 NJOWQKJICXXAMR-UHFFFAOYSA-N 50473124 CHEMBL157799 D(2) dopamine receptor Rattus norvegicus 1230 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473124&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10826687 433940389 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154493 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154496 CCN1CCc2cc(OC)cc3Oc4ccccc4CC1c23 InChI=1S/C19H21NO2/c1-3-20-9-8-14-10-15(21-2)12-18-19(14)16(20)11-13-6-4-5-7-17(13)22-18/h4-7,10,12,16H,3,8-9,11H2,1-2H3 GLJAYJNZUWWZNL-UHFFFAOYSA-N 50473125 CHEMBL155002 D(2) dopamine receptor Rattus norvegicus 8511 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473125&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10541919 433940390 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154497 CCN1CCc2c(Br)ccc(O)c2C1Cc1cc(OC)ccc1Br InChI=1S/C19H21Br2NO2/c1-3-22-9-8-14-16(21)6-7-18(23)19(14)17(22)11-12-10-13(24-2)4-5-15(12)20/h4-7,10,17,23H,3,8-9,11H2,1-2H3 OIDAOTIYTAARMN-UHFFFAOYSA-N 50473121 CHEMBL155351 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10623632 433940386 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154499 COc1ccc(Br)c(CC2N(C)CCc3c(Br)ccc(O)c23)c1 InChI=1S/C18H19Br2NO2/c1-21-8-7-13-15(20)5-6-17(22)18(13)16(21)10-11-9-12(23-2)3-4-14(11)19/h3-6,9,16,22H,7-8,10H2,1-2H3 IQBSBUKJNHJCGU-UHFFFAOYSA-N 50473127 CHEMBL154301 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473127&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10813037 433940392 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154501 CCN1CCc2c(Br)ccc3Oc4ccc(OC)cc4CC1c23 InChI=1S/C19H20BrNO2/c1-3-21-9-8-14-15(20)5-7-18-19(14)16(21)11-12-10-13(22-2)4-6-17(12)23-18/h4-7,10,16H,3,8-9,11H2,1-2H3 VNJVDPRFGIWXFI-UHFFFAOYSA-N 50473126 CHEMBL436042 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473126&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10833201 433940391 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154503 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 724 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154505 COc1ccc2Oc3ccc(Br)c4CCN(C)C(Cc2c1)c34 InChI=1S/C18H18BrNO2/c1-20-8-7-13-14(19)4-6-17-18(13)15(20)10-11-9-12(21-2)3-5-16(11)22-17/h3-6,9,15H,7-8,10H2,1-2H3 PUNAIHMZORVACK-UHFFFAOYSA-N 50473116 CHEMBL156011 D(2) dopamine receptor Rattus norvegicus 851 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473116&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10044041 433940381 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154506 CCCN1CCc2cc(OC)cc3Oc4ccccc4CC1c23 InChI=1S/C20H23NO2/c1-3-9-21-10-8-15-11-16(22-2)13-19-20(15)17(21)12-14-6-4-5-7-18(14)23-19/h4-7,11,13,17H,3,8-10,12H2,1-2H3 VBCXNXPMHJAVIC-UHFFFAOYSA-N 50473118 CHEMBL346792 D(2) dopamine receptor Rattus norvegicus 3467 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10495108 433940383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154508 CN1CCc2cccc3Oc4ccc(O)cc4CC1c23 InChI=1S/C17H17NO2/c1-18-8-7-11-3-2-4-16-17(11)14(18)10-12-9-13(19)5-6-15(12)20-16/h2-6,9,14,19H,7-8,10H2,1H3 YYADTQZDIVKTET-UHFFFAOYSA-N 50202327 1-methyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-10-ol::CHEMBL155352 D(2) dopamine receptor Rattus norvegicus 724 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10264969 104081904 CHEMBL155352 ZINC12355991 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154510 CCN1CCc2cccc3Oc4ccc(OC)cc4CC1c23 InChI=1S/C19H21NO2/c1-3-20-10-9-13-5-4-6-18-19(13)16(20)12-14-11-15(21-2)7-8-17(14)22-18/h4-8,11,16H,3,9-10,12H2,1-2H3 GWBJQVOEGZWAOJ-UHFFFAOYSA-N 50473117 CHEMBL348465 D(2) dopamine receptor Rattus norvegicus 1862 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473117&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10589978 433940382 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154512 COc1cc(Br)cc2CCN(C)C(Cc3ccccc3O)c12 InChI=1S/C18H20BrNO2/c1-20-8-7-13-9-14(19)11-17(22-2)18(13)15(20)10-12-5-3-4-6-16(12)21/h3-6,9,11,15,21H,7-8,10H2,1-2H3 DLXCJDASYOASBG-UHFFFAOYSA-N 50473120 CHEMBL350471 D(2) dopamine receptor Rattus norvegicus 1820 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473120&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10498848 433940385 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154514 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2.1 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154518 CCCN1CCc2c(Br)ccc(O)c2C1Cc1cc(OC)ccc1Br InChI=1S/C20H23Br2NO2/c1-3-9-23-10-8-15-17(22)6-7-19(24)20(15)18(23)12-13-11-14(25-2)4-5-16(13)21/h4-7,11,18,24H,3,8-10,12H2,1-2H3 BZIBNCUWDSRNQB-UHFFFAOYSA-N 50473115 CHEMBL154015 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50473115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50473115&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10672006 433940380 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51154520 CCCN1CCc2cccc3Oc4ccc(O)cc4CC1c23 InChI=1S/C19H21NO2/c1-2-9-20-10-8-13-4-3-5-18-19(13)16(20)12-14-11-15(21)6-7-17(14)22-18/h3-7,11,16,21H,2,8-10,12H2,1H3 JKQPZWDOWPWNQV-UHFFFAOYSA-N 50202304 1-Propyl-2,3,12,12a-tetrahydro-1H-7-oxa-1-aza-pleiaden-10-ol::CHEMBL345240 D(2) dopamine receptor Rattus norvegicus <10000 ChEMBL 10.1021/jm991034o 10.7270/Q2X35161 10691686 Claudi, F; Di Stefano, A; Napolitani, F; Cingolani, GM; Giorgioni, G; Fontenla, JA; Montenegro, GY; Rivas, ME; Rosa, E; Michelotto, B; Orlando, G; Brunetti, L Universit£ di Camerino http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202304 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202304&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10685300 104081881 CHEMBL345240 ZINC13805122 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146302 O=C(CCN1CCN(CC1)c1ccccn1)c1cc2CCCN3C(=O)CCc(c1)c23 InChI=1S/C24H28N4O2/c29-21(8-11-26-12-14-27(15-13-26)22-5-1-2-9-25-22)20-16-18-4-3-10-28-23(30)7-6-19(17-20)24(18)28/h1-2,5,9,16-17H,3-4,6-8,10-15H2 RMLWGVUABSFINB-UHFFFAOYSA-N 50469538 CHEMBL4284469 D(2) dopamine receptor Rattus norvegicus 1661 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469538&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103400 433936803 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51146303 Fc1ccc2c(noc2c1)C1CCN(CCCCCc2cc3CCN4c3c(CCC4=O)c2)CC1 InChI=1S/C28H32FN3O2/c29-23-6-7-24-25(18-23)34-30-27(24)20-9-13-31(14-10-20)12-3-1-2-4-19-16-21-5-8-26(33)32-15-11-22(17-19)28(21)32/h6-7,16-18,20H,1-5,8-15H2 AFEOSDDRQFZPOQ-UHFFFAOYSA-N 50469510 CHEMBL4291389 D(2) dopamine receptor Rattus norvegicus 43 ChEMBL 10.1021/acs.jmedchem.8b01096 10.7270/Q2NS0XK7 30383372 Cao, X; Zhang, Y; Chen, Y; Qiu, Y; Yu, M; Xu, X; Liu, X; Liu, BF; Zhang, L; Zhang, G Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50469510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50469510&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 129103319 433936775 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153512 Fc1ccc(cc1Cl)C(=O)N1CCC(F)(CNCc2cccc(n2)-c2ccco2)CC1 InChI=1S/C23H22ClF2N3O2/c24-18-13-16(6-7-19(18)25)22(30)29-10-8-23(26,9-11-29)15-27-14-17-3-1-4-20(28-17)21-5-2-12-31-21/h1-7,12-13,27H,8-11,14-15H2 CCUGUSMEABKPDB-UHFFFAOYSA-N 50472568 CHEMBL42393 D(2) dopamine receptor Rattus norvegicus 2239 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472568 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472568&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10647006 433939833 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153516 FC1(CNCc2cccc(n2)-c2cc[nH]n2)CCN(CC1)C(=O)c1ccc(Cl)c(Cl)c1 InChI=1S/C22H22Cl2FN5O/c23-17-5-4-15(12-18(17)24)21(31)30-10-7-22(25,8-11-30)14-26-13-16-2-1-3-19(28-16)20-6-9-27-29-20/h1-6,9,12,26H,7-8,10-11,13-14H2,(H,27,29) UTIFBMOIOKNYIT-UHFFFAOYSA-N 50472596 CHEMBL46582 D(2) dopamine receptor Rattus norvegicus 4074 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472596 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472596&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10813901 433939861 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153518 CNc1cccc(CNCC2CCN(CC2)C(=O)c2ccc(Cl)c(Cl)c2)n1 InChI=1S/C20H24Cl2N4O/c1-23-19-4-2-3-16(25-19)13-24-12-14-7-9-26(10-8-14)20(27)15-5-6-17(21)18(22)11-15/h2-6,11,14,24H,7-10,12-13H2,1H3,(H,23,25) SFBSYUXHSUTLDP-UHFFFAOYSA-N 50472090 CHEMBL44904 D(2) dopamine receptor Rattus norvegicus 3090 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472090&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10787547 433939355 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153521 CN(C)c1cccc(CNCC2(F)CCN(CC2)C(=O)c2ccc(F)c(Cl)c2)n1 InChI=1S/C21H25ClF2N4O/c1-27(2)19-5-3-4-16(26-19)13-25-14-21(24)8-10-28(11-9-21)20(29)15-6-7-18(23)17(22)12-15/h3-7,12,25H,8-11,13-14H2,1-2H3 KTNPWLGBAAFMNK-UHFFFAOYSA-N 50472566 CHEMBL360319 D(2) dopamine receptor Rattus norvegicus 275 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472566 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472566&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10740939 433939831 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153532 CNc1cccc(CNCC2(F)CCN(CC2)C(=O)c2ccc(Cl)c(Cl)c2)n1 InChI=1S/C20H23Cl2FN4O/c1-24-18-4-2-3-15(26-18)12-25-13-20(23)7-9-27(10-8-20)19(28)14-5-6-16(21)17(22)11-14/h2-6,11,25H,7-10,12-13H2,1H3,(H,24,26) NDYWHACDLHAKHK-UHFFFAOYSA-N 50472589 CHEMBL44118 D(2) dopamine receptor Rattus norvegicus 398 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472589&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10670050 433939854 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153543 FC1(CNCc2cccc(n2)N2CCC2)CCN(CC1)C(=O)c1ccc(Cl)c(Cl)c1 InChI=1S/C22H25Cl2FN4O/c23-18-6-5-16(13-19(18)24)21(30)29-11-7-22(25,8-12-29)15-26-14-17-3-1-4-20(27-17)28-9-2-10-28/h1,3-6,13,26H,2,7-12,14-15H2 SEEAACXFQOFBJU-UHFFFAOYSA-N 50472599 CHEMBL45423 D(2) dopamine receptor Rattus norvegicus 309 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472599&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10789756 433939864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153553 FC1(CNCc2cccc(n2)-c2nccs2)CCN(CC1)C(=O)c1ccc(Cl)c(Cl)c1 InChI=1S/C22H21Cl2FN4OS/c23-17-5-4-15(12-18(17)24)21(30)29-9-6-22(25,7-10-29)14-26-13-16-2-1-3-19(28-16)20-27-8-11-31-20/h1-5,8,11-12,26H,6-7,9-10,13-14H2 NYFVZSBKYHXQCT-UHFFFAOYSA-N 50472577 CHEMBL46512 D(2) dopamine receptor Rattus norvegicus 3388 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472577&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10743303 433939842 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153556 CN(C)c1cccc(CNCC2(F)CCN(CC2)C(=O)c2ccc(C)c(Cl)c2)n1 InChI=1S/C22H28ClFN4O/c1-16-7-8-17(13-19(16)23)21(29)28-11-9-22(24,10-12-28)15-25-14-18-5-4-6-20(26-18)27(2)3/h4-8,13,25H,9-12,14-15H2,1-3H3 ZVOKHVDANBFMRT-UHFFFAOYSA-N 50472595 CHEMBL295662 D(2) dopamine receptor Rattus norvegicus 129 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472595 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472595&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10764513 433939860 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51153563 FC1(CNCc2cccc(n2)-c2ccco2)CCN(CC1)C(=O)c1ccc(Cl)c(Cl)c1 InChI=1S/C23H22Cl2FN3O2/c24-18-7-6-16(13-19(18)25)22(30)29-10-8-23(26,9-11-29)15-27-14-17-3-1-4-20(28-17)21-5-2-12-31-21/h1-7,12-13,27H,8-11,14-15H2 RJKIATOONRELLI-UHFFFAOYSA-N 50472583 CHEMBL43146 D(2) dopamine receptor Rattus norvegicus 1202 ChEMBL 10.1021/jm9806906 10.7270/Q2MS3WHR 10229633 Vacher, B; Bonnaud, B; Funes, P; Jubault, N; Koek, W; Assié, MB; Cosi, C; Kleven, M Pierre Fabre Research Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50472583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50472583&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10718870 433939848 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184641 CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 50018958 CHEBI:75401::QUINPIROLE D(2) dopamine receptor Rattus norvegicus 4321 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 103930000 ZINC13490706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184642 CCCN1CCO[C@H]2[C@H]1CCc1ccc(cc21)C(N)=O InChI=1S/C16H22N2O2/c1-2-7-18-8-9-20-15-13-10-12(16(17)19)4-3-11(13)5-6-14(15)18/h3-4,10,14-15H,2,5-9H2,1H3,(H2,17,19)/t14-,15-/m1/s1 XKTRZPQOQOCNJU-HUUCEWRRSA-N 86473 S32504 (+) D(2) dopamine receptor Rattus norvegicus 406 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15389743 136352522 ZINC40819117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184643 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.520000 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184644 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Rattus norvegicus 7.9 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184647 CCCN1CCO[C@H]2[C@H]1CCc1ccc(cc21)C(N)=O InChI=1S/C16H22N2O2/c1-2-7-18-8-9-20-15-13-10-12(16(17)19)4-3-11(13)5-6-14(15)18/h3-4,10,14-15H,2,5-9H2,1H3,(H2,17,19)/t14-,15-/m1/s1 XKTRZPQOQOCNJU-HUUCEWRRSA-N 86473 S32504 (+) D(2) dopamine receptor Rattus norvegicus 50 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86473&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15389743 136352522 ZINC40819117 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184648 CCCN[C@H]1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1 FASDKYOPVNHBLU-ZETCQYMHSA-N 50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570 D(2) dopamine receptor Rattus norvegicus 22 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 119570 104010405 8356 CHEMBL301265 DB00413 ZINC03781664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184650 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.6 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184651 CCCN1CCC[C@@H]2Cc3n[nH]cc3C[C@@H]12 InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 FTSUPYGMFAPCFZ-ZWNOBZJWSA-N 50018958 CHEBI:75401::QUINPIROLE D(2) dopamine receptor Rattus norvegicus 4784 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50018958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50018958&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 54562 103930000 ZINC13490706 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184652 CNc1cc(OC)c(cc1Cl)C(=O)N[C@@H]1CCN(Cc2ccccc2)[C@@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m1/s1 KRVOJOCLBAAKSJ-RDTXWAMCSA-N 50487259 CHEBI:64219::[3H]NEMONAPRIDE D(2) dopamine receptor Rattus norvegicus 0.014000 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487259&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 156333 433954524 C12915 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184656 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 1.9 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184665 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 180 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184666 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 135 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184667 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 3260 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184668 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 0.570000 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184669 CCCN(CCC)CCc1cccc2NC(=O)Cc12 InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19) UHSKFQJFRQCDBE-UHFFFAOYSA-N 50020680 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE D(2) dopamine receptor Rattus norvegicus 1803 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5095 103931441 8888 CHEMBL589 DB00268 7295 C07564 ZINC00002041 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184670 CCCN[C@H]1CCc2nc(N)sc2C1 InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m0/s1 FASDKYOPVNHBLU-ZETCQYMHSA-N 50116766 (-)-Pramipexole::(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine::2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)-::CHEMBL301265::PRAMIPEXOLE::cid_119570 D(2) dopamine receptor Rattus norvegicus 450 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50116766 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50116766&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search G6L 7CMU 119570 104010405 8356 CHEMBL301265 DB00413 ZINC03781664 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184671 CCCN(CCC)C1CCc2ccc(O)cc2C1 InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 BLYMJBIZMIGWFK-UHFFFAOYSA-N 50020222 (+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::(+/-)-7-hydroxy-2-(N,N-di-n-propylamino)tetralin::(R,S) 7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol::7-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-2-ol (DP-7-ADTN)::7-OH-DPAT::7-OH-DPAT,(+)::7-OH-DPAT,(-)::7-hydroxy-2-(dipropylamino)tetralin::CHEMBL1255966::CHEMBL285755 D(2) dopamine receptor Rattus norvegicus 192 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1219 103931136 CHEMBL1255966CHEMBL285755 950 ZINC03870311 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184672 CN1CCc2cccc-3c2[C@H]1Cc1ccc(O)c(O)c-31 InChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1 VMWNQDUVQKEIOC-CYBMUJFWSA-N 50001955 (-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(APO)::(Apomorphine) 6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol (apomorphine)::(R)-6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol(apomorphine)::(apomorphine)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol ((R)-apomorphine)::6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol((R)-apomorphine)::APOKYN::APOMORPHINE::APOMORPHINE HYDROCHLORIDE::APOMORPHINE6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol::CHEMBL53 D(2) dopamine receptor Rattus norvegicus 118 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001955&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search OR9 7JVQ 6005 103916308 48538 CHEMBL53 DB00714 33 ZINC00009073 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184673 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 3140 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184674 O=C(NCCCCN1C[C@@H]2COc3ccc(cc3[C@H]2C1)C#N)c1ccc(cc1)-c1ccccc1 InChI=1S/C29H29N3O2/c30-17-21-8-13-28-26(16-21)27-19-32(18-25(27)20-34-28)15-5-4-14-31-29(33)24-11-9-23(10-12-24)22-6-2-1-3-7-22/h1-3,6-13,16,25,27H,4-5,14-15,18-20H2,(H,31,33)/t25-,27+/m1/s1 QQJHRQZZCNYDMX-VPUSJEBWSA-N 85672 S33084 D(2) dopamine receptor Rattus norvegicus 205 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85672&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9868452 136351772 ZINC03941217 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184675 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 1.0 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184676 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 64 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184678 CNc1cc(OC)c(cc1Cl)C(=O)N[C@@H]1CCN(Cc2ccccc2)[C@@H]1C InChI=1S/C21H26ClN3O2/c1-14-18(9-10-25(14)13-15-7-5-4-6-8-15)24-21(26)16-11-17(22)19(23-2)12-20(16)27-3/h4-8,11-12,14,18,23H,9-10,13H2,1-3H3,(H,24,26)/t14-,18-/m1/s1 KRVOJOCLBAAKSJ-RDTXWAMCSA-N 50487259 CHEBI:64219::[3H]NEMONAPRIDE D(2) dopamine receptor Rattus norvegicus 0.016000 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50487259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50487259&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 156333 433954524 C12915 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184681 CCCN(CCC)CCc1cccc2NC(=O)Cc12 InChI=1S/C16H24N2O/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15/h5-7H,3-4,8-12H2,1-2H3,(H,17,19) UHSKFQJFRQCDBE-UHFFFAOYSA-N 50020680 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one::CHEMBL589::ROPINIROLE D(2) dopamine receptor Rattus norvegicus 76 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020680&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 5095 103931441 8888 CHEMBL589 DB00268 7295 C07564 ZINC00002041 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184686 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184687 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 63 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184688 COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1 InChI=1S/C26H31N3O2/c1-31-25-11-5-4-10-24(25)29-18-16-28(17-19-29)15-7-6-14-27-26(30)23-13-12-21-8-2-3-9-22(21)20-23/h2-5,8-13,20H,6-7,14-19H2,1H3,(H,27,30) MNHDKMDLOJSCGN-UHFFFAOYSA-N 50119380 CHEMBL25236::CHEMBL540612::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide::Naphthalene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3038495 104012598 CHEMBL25236CHEMBL540612 ZINC03917109 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184689 CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13 InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1 YEHCICAEULNIGD-MZMPZRCHSA-N 50017543 (6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium::(6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::5-Bromo-7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinoline-9-carboxylic acid (10b-hydroxy-5-isobutyl-2-isopropyl-3,6-dioxo-octahydro-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-amide::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinolin-7-ium(Pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline(pergolide)::9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline, mesylate (Pergolide)::CHEMBL531::PERGOLIDE::Permax::[2-(1H-Indol-4-yl)-ethyl]-methyl-amine::cid_47811 D(2) dopamine receptor Rattus norvegicus 32 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50017543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50017543&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 47811 103928811 63617 CHEMBL531 DB01186 48 C07425 ZINC03786466 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184690 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 13 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184692 CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3 KVWDHTXUZHCGIO-UHFFFAOYSA-N 35254 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine::CHEMBL715::Olansek::US8802672, Olanzapine::Zyprexa::olanzapine D(2) dopamine receptor Rattus norvegicus 15 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35254&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4585 85753333 7735 CHEMBL715 DB00334 47 C07322 ZINC52957434 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51184693 COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1 InChI=1S/C26H31N3O2/c1-31-25-11-5-4-10-24(25)29-18-16-28(17-19-29)15-7-6-14-27-26(30)23-13-12-21-8-2-3-9-22(21)20-23/h2-5,8-13,20H,6-7,14-19H2,1H3,(H,27,30) MNHDKMDLOJSCGN-UHFFFAOYSA-N 50119380 CHEMBL25236::CHEMBL540612::N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide::Naphthalene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1007/s00044-004-0006-x 10.7270/Q2377CM7 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3038495 104012598 CHEMBL25236CHEMBL540612 ZINC03917109 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197374 Clc1ccc(cc1)-n1cc(CCCCN2CCN(CC2)c2ccccc2)cn1 InChI=1S/C23H27ClN4/c24-21-9-11-23(12-10-21)28-19-20(18-25-28)6-4-5-13-26-14-16-27(17-15-26)22-7-2-1-3-8-22/h1-3,7-12,18-19H,4-6,13-17H2 UMGYDBQRRRBPHS-UHFFFAOYSA-N 50492801 CHEMBL2414357 D(2) dopamine receptor Rattus norvegicus 250 ChEMBL 10.1016/j.ejmech.2013.05.027 10.7270/Q2514253 23792350 Pompeu, TE; Alves, FR; Figueiredo, CD; Antonio, CB; Herzfeldt, V; Moura, BC; Rates, SM; Barreiro, EJ; Fraga, CA; Noël, F Universidade Federal do Rio de Janeiro http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72205046 433960066 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197375 Clc1ccc(cc1)-n1cc(CN2CCN(CC2)c2ccccc2)cn1 InChI=1S/C20H21ClN4/c21-18-6-8-20(9-7-18)25-16-17(14-22-25)15-23-10-12-24(13-11-23)19-4-2-1-3-5-19/h1-9,14,16H,10-13,15H2 MHJWMIITIMUUKU-UHFFFAOYSA-N 50308002 1-[(1-(4-Chlorophenyl)-1H-pyrazol-4-yl)methyl]-4-phenylpiperazine::CHEMBL597601 D(2) dopamine receptor Rattus norvegicus 390 ChEMBL 10.1016/j.ejmech.2013.05.027 10.7270/Q2514253 23792350 Pompeu, TE; Alves, FR; Figueiredo, CD; Antonio, CB; Herzfeldt, V; Moura, BC; Rates, SM; Barreiro, EJ; Fraga, CA; Noël, F Universidade Federal do Rio de Janeiro http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50308002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50308002&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11624518 104162363 CHEMBL597601 ZINC53184753 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51203232 Clc1ccccc1N1CCN(CCCc2ccccc2)CC1 InChI=1S/C19H23ClN2/c20-18-10-4-5-11-19(18)22-15-13-21(14-16-22)12-6-9-17-7-2-1-3-8-17/h1-5,7-8,10-11H,6,9,12-16H2 WGGWRKFUAXNQEF-UHFFFAOYSA-N 50494707 CHEMBL3093270 D(2) dopamine receptor Rattus norvegicus 77 ChEMBL 10.1016/j.bmcl.2013.09.038 10.7270/Q2J969B5 24211020 Motel, WC; Healy, JR; Viard, E; Pouw, B; Martin, K; Matsumoto, RR; Coop, A University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50494707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50494707&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2845629 433961972 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51203248 Clc1cccc(c1)N1CCN(CCCc2ccccc2)CC1 InChI=1S/C19H23ClN2/c20-18-9-4-10-19(16-18)22-14-12-21(13-15-22)11-5-8-17-6-2-1-3-7-17/h1-4,6-7,9-10,16H,5,8,11-15H2 LJDXYTBGUJEQSY-UHFFFAOYSA-N 50007412 1-(3-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine::CHEMBL325262 D(2) dopamine receptor Rattus norvegicus 128 ChEMBL 10.1016/j.bmcl.2013.09.038 10.7270/Q2J969B5 24211020 Motel, WC; Healy, JR; Viard, E; Pouw, B; Martin, K; Matsumoto, RR; Coop, A University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007412&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 4992580 103920687 CHEMBL325262 ZINC00757031 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51203249 Clc1cccc(c1)N1CCN(CCc2ccccc2)CC1 InChI=1S/C18H21ClN2/c19-17-7-4-8-18(15-17)21-13-11-20(12-14-21)10-9-16-5-2-1-3-6-16/h1-8,15H,9-14H2 NKMGWZZAFWDLFG-UHFFFAOYSA-N 50007404 1-(3-Chloro-phenyl)-4-phenethyl-piperazine::CHEMBL113621 D(2) dopamine receptor Rattus norvegicus 327 ChEMBL 10.1016/j.bmcl.2013.09.038 10.7270/Q2J969B5 24211020 Motel, WC; Healy, JR; Viard, E; Pouw, B; Martin, K; Matsumoto, RR; Coop, A University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007404&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2845469 103920679 CHEMBL113621 ZINC00216834 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51203250 Clc1ccccc1N1CCN(CCc2ccccc2)CC1 InChI=1S/C18H21ClN2/c19-17-8-4-5-9-18(17)21-14-12-20(13-15-21)11-10-16-6-2-1-3-7-16/h1-9H,10-15H2 GPLJHNLLDGQNDU-UHFFFAOYSA-N 50494706 CHEMBL3093268 D(2) dopamine receptor Rattus norvegicus 67 ChEMBL 10.1016/j.bmcl.2013.09.038 10.7270/Q2J969B5 24211020 Motel, WC; Healy, JR; Viard, E; Pouw, B; Martin, K; Matsumoto, RR; Coop, A University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50494706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50494706&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 409926 433961971 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51203251 C(CN1CCN(CC1)c1ccccn1)Cc1ccccc1 InChI=1S/C18H23N3/c1-2-7-17(8-3-1)9-6-12-20-13-15-21(16-14-20)18-10-4-5-11-19-18/h1-5,7-8,10-11H,6,9,12-16H2 QCVDHRLSVUSYNT-UHFFFAOYSA-N 50109383 1-(3-Phenyl-propyl)-4-pyridin-2-yl-piperazine::1-(3-phenylpropyl)-4-(pyridin-2-yl)piperazine::CHEMBL145867 D(2) dopamine receptor Rattus norvegicus 940 ChEMBL 10.1016/j.bmcl.2013.09.038 10.7270/Q2J969B5 24211020 Motel, WC; Healy, JR; Viard, E; Pouw, B; Martin, K; Matsumoto, RR; Coop, A University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 667735 104004348 CHEMBL145867 ZINC19633972 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51203258 Clc1ccc(cc1)N1CCN(CCc2ccccc2)CC1 InChI=1S/C18H21ClN2/c19-17-6-8-18(9-7-17)21-14-12-20(13-15-21)11-10-16-4-2-1-3-5-16/h1-9H,10-15H2 DGNMYXGLQJVLLI-UHFFFAOYSA-N 50494708 CHEMBL3093269 D(2) dopamine receptor Rattus norvegicus 834 ChEMBL 10.1016/j.bmcl.2013.09.038 10.7270/Q2J969B5 24211020 Motel, WC; Healy, JR; Viard, E; Pouw, B; Martin, K; Matsumoto, RR; Coop, A University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50494708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50494708&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2845455 433961973 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51203259 Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1 InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2 NAFPAUNPTMADIM-UHFFFAOYSA-N 50007410 1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine::CHEMBL112125 D(2) dopamine receptor Rattus norvegicus 660 ChEMBL 10.1016/j.bmcl.2013.09.038 10.7270/Q2J969B5 24211020 Motel, WC; Healy, JR; Viard, E; Pouw, B; Martin, K; Matsumoto, RR; Coop, A University of Maryland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007410&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3299322 103920685 CHEMBL112125 ZINC06548476 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197957 CN1CCc2cc3OCOc3c3-c4ccccc4CC1c23 InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 JCTYWRARKVGOBK-UHFFFAOYSA-N 50284797 7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline::CHEMBL36654::GNF-Pf-4466::cid_235224 D(2) dopamine receptor Rattus norvegicus 83 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 235224 104126368 CHEMBL36654 ZINC00306698 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197958 CN(C)CCc1cc(O)c(O)c2c1ccc1ccccc21 InChI=1S/C18H19NO2/c1-19(2)10-9-13-11-16(20)18(21)17-14-6-4-3-5-12(14)7-8-15(13)17/h3-8,11,20-21H,9-10H2,1-2H3 KDGLPBJRODNQHP-UHFFFAOYSA-N 50492965 CHEMBL2414992 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492965&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71817345 433960230 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197959 CN1CCc2cc(O)c(O)c3-c4ccccc4CC1c23 InChI=1S/C17H17NO2/c1-18-7-6-11-9-14(19)17(20)16-12-5-3-2-4-10(12)8-13(18)15(11)16/h2-5,9,13,19-20H,6-8H2,1H3 SYKWSIUDXOQIDR-UHFFFAOYSA-N 50492966 CHEMBL2414991 D(2) dopamine receptor Rattus norvegicus 39 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 151086 433960231 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197962 CN(C)CCc1cc(O)c(O)c2c1ccc1ccccc21 InChI=1S/C18H19NO2/c1-19(2)10-9-13-11-16(20)18(21)17-14-6-4-3-5-12(14)7-8-15(13)17/h3-8,11,20-21H,9-10H2,1-2H3 KDGLPBJRODNQHP-UHFFFAOYSA-N 50492965 CHEMBL2414992 D(2) dopamine receptor Rattus norvegicus 38.5 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492965&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71817345 433960230 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197963 CN1CCc2cc(O)c(O)c3-c4ccccc4CC1c23 InChI=1S/C17H17NO2/c1-18-7-6-11-9-14(19)17(20)16-12-5-3-2-4-10(12)8-13(18)15(11)16/h2-5,9,13,19-20H,6-8H2,1H3 SYKWSIUDXOQIDR-UHFFFAOYSA-N 50492966 CHEMBL2414991 D(2) dopamine receptor Rattus norvegicus 38.6 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492966&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 151086 433960231 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197964 COc1cc2CCN(C)C3Cc4ccccc4-c(c1OC)c23 InChI=1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3 ORJVQPIHKOARKV-UHFFFAOYSA-N 50492967 (+/-)-NUCIFERINE D(2) dopamine receptor Rattus norvegicus 173 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3108374 433960232 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197967 CN(C)CCc1cc2OCOc2c2c1ccc1ccccc21 InChI=1S/C19H19NO2/c1-20(2)10-9-14-11-17-19(22-12-21-17)18-15-6-4-3-5-13(15)7-8-16(14)18/h3-8,11H,9-10,12H2,1-2H3 FXTBDJZGDJJCQU-UHFFFAOYSA-N 69679 Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethyl)-amine::MLS001207641::N,N-dimethyl-2-(5-naphtho[2,1-g][1,3]benzodioxolyl)ethanamine;hydrochloride::N,N-dimethyl-2-naphtho[2,1-g][1,3]benzodioxol-5-yl-ethanamine;hydrochloride::N,N-dimethyl-2-naphtho[2,1-g][1,3]benzodioxol-5-ylethanamine;hydrochloride::SMR000517938::US9211296, Table 7, Compd: 10::cid_24746882::dimethyl(2-naphtho[2,1-g][1,3]benzodioxol-5-ylethyl)amine;hydrochloride D(2) dopamine receptor Rattus norvegicus 65 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 161379 252647844 ZINC00187287 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197971 CN1CCc2cc3OCOc3c3-c4ccccc4CC1c23 InChI=1S/C18H17NO2/c1-19-7-6-12-9-15-18(21-10-20-15)17-13-5-3-2-4-11(13)8-14(19)16(12)17/h2-5,9,14H,6-8,10H2,1H3 JCTYWRARKVGOBK-UHFFFAOYSA-N 50284797 7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline::CHEMBL36654::GNF-Pf-4466::cid_235224 D(2) dopamine receptor Rattus norvegicus 84 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50284797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50284797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 235224 104126368 CHEMBL36654 ZINC00306698 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197972 COc1cc(CCN(C)C)c2ccc3ccccc3c2c1OC InChI=1S/C20H23NO2/c1-21(2)12-11-15-13-18(22-3)20(23-4)19-16-8-6-5-7-14(16)9-10-17(15)19/h5-10,13H,11-12H2,1-4H3 UZZFAUDNCIFFPM-UHFFFAOYSA-N 50187683 CHEMBL1186488 D(2) dopamine receptor Rattus norvegicus 321 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187683&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 96918 346534871 CHEMBL1186488 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197974 COc1cc(CCN(C)C)c2ccc3ccccc3c2c1OC InChI=1S/C20H23NO2/c1-21(2)12-11-15-13-18(22-3)20(23-4)19-16-8-6-5-7-14(16)9-10-17(15)19/h5-10,13H,11-12H2,1-4H3 UZZFAUDNCIFFPM-UHFFFAOYSA-N 50187683 CHEMBL1186488 D(2) dopamine receptor Rattus norvegicus 323 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187683&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 96918 346534871 CHEMBL1186488 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197977 COc1cc2CCN(C)C3Cc4ccccc4-c(c1OC)c23 InChI=1S/C19H21NO2/c1-20-9-8-13-11-16(21-2)19(22-3)18-14-7-5-4-6-12(14)10-15(20)17(13)18/h4-7,11,15H,8-10H2,1-3H3 ORJVQPIHKOARKV-UHFFFAOYSA-N 50492967 (+/-)-NUCIFERINE D(2) dopamine receptor Rattus norvegicus 173 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492967&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3108374 433960232 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197978 CN(C)CCc1cc2OCOc2c2c1ccc1ccccc21 InChI=1S/C19H19NO2/c1-20(2)10-9-14-11-17-19(22-12-21-17)18-15-6-4-3-5-13(15)7-8-16(14)18/h3-8,11H,9-10,12H2,1-2H3 FXTBDJZGDJJCQU-UHFFFAOYSA-N 69679 Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethyl)-amine::MLS001207641::N,N-dimethyl-2-(5-naphtho[2,1-g][1,3]benzodioxolyl)ethanamine;hydrochloride::N,N-dimethyl-2-naphtho[2,1-g][1,3]benzodioxol-5-yl-ethanamine;hydrochloride::N,N-dimethyl-2-naphtho[2,1-g][1,3]benzodioxol-5-ylethanamine;hydrochloride::SMR000517938::US9211296, Table 7, Compd: 10::cid_24746882::dimethyl(2-naphtho[2,1-g][1,3]benzodioxol-5-ylethyl)amine;hydrochloride D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1016/j.bmcl.2013.06.078 10.7270/Q2BK1G9S 23886690 Moreno, L; Cabedo, N; Ivorra, MD; Sanz, MJ; Castel, AL; Carmen Álvarez, M; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=69679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=69679&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 161379 252647844 ZINC00187287 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199133 Oc1ccc2CN3CCc4cc(O)c(O)cc4C3Cc2c1 InChI=1S/C17H17NO3/c19-13-2-1-11-9-18-4-3-10-7-16(20)17(21)8-14(10)15(18)6-12(11)5-13/h1-2,5,7-8,15,19-21H,3-4,6,9H2 RIEBJAWIEINKIS-UHFFFAOYSA-N 50493348 CHEMBL2425375 D(2) dopamine receptor Rattus norvegicus 389 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708126 433960613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199135 Oc1cccc2CC3N(CCc4cc5OCOc5cc34)Cc12 InChI=1S/C18H17NO3/c20-16-3-1-2-11-6-15-13-8-18-17(21-10-22-18)7-12(13)4-5-19(15)9-14(11)16/h1-3,7-8,15,20H,4-6,9-10H2 VNNDXBUBKOYLIM-UHFFFAOYSA-N 50493350 CHEMBL2425378 D(2) dopamine receptor Rattus norvegicus 28.2 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708128 433960615 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199136 Oc1ccc2CN3CCc4cc(O)c(O)cc4C3Cc2c1 InChI=1S/C17H17NO3/c19-13-2-1-11-9-18-4-3-10-7-16(20)17(21)8-14(10)15(18)6-12(11)5-13/h1-2,5,7-8,15,19-21H,3-4,6,9H2 RIEBJAWIEINKIS-UHFFFAOYSA-N 50493348 CHEMBL2425375 D(2) dopamine receptor Rattus norvegicus 396 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708126 433960613 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199137 COc1cccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc12 InChI=1S/C20H23NO3/c1-22-18-6-4-5-13-9-17-15-11-20(24-3)19(23-2)10-14(15)7-8-21(17)12-16(13)18/h4-6,10-11,17H,7-9,12H2,1-3H3 BIWCHVGMGDYNNS-UHFFFAOYSA-N 50493351 CHEMBL2425374 D(2) dopamine receptor Rattus norvegicus 393 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57580939 433960616 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199138 COc1ccc2CN3CCc4cc(O)c(O)cc4C3Cc2c1 InChI=1S/C18H19NO3/c1-22-14-3-2-12-10-19-5-4-11-8-17(20)18(21)9-15(11)16(19)7-13(12)6-14/h2-3,6,8-9,16,20-21H,4-5,7,10H2,1H3 QENRDSSNVLVQMF-UHFFFAOYSA-N 50493352 CHEMBL2425371 D(2) dopamine receptor Rattus norvegicus 78 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71110301 433960617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199139 COc1ccc2CN3CCc4cc(OCc5ccccc5)c(OCc5ccccc5)cc4C3Cc2c1 InChI=1S/C32H31NO3/c1-34-28-13-12-26-20-33-15-14-25-18-31(35-21-23-8-4-2-5-9-23)32(36-22-24-10-6-3-7-11-24)19-29(25)30(33)17-27(26)16-28/h2-13,16,18-19,30H,14-15,17,20-22H2,1H3 URBGRKGOMMSWMO-UHFFFAOYSA-N 50493353 CHEMBL2425370 D(2) dopamine receptor Rattus norvegicus 40866 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493353&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708060 433960618 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199140 COc1ccc2CN3CCc4cc(Cl)c(OC)cc4C3Cc2c1 InChI=1S/C19H20ClNO2/c1-22-15-4-3-13-11-21-6-5-12-8-17(20)19(23-2)10-16(12)18(21)9-14(13)7-15/h3-4,7-8,10,18H,5-6,9,11H2,1-2H3 MTAWQOIMTSBLBR-UHFFFAOYSA-N 50493354 CHEMBL2425368 D(2) dopamine receptor Rattus norvegicus 2046 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493354&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708058 433960619 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199146 Oc1ccc2CN3CCc4cc5OCOc5cc4C3Cc2c1 InChI=1S/C18H17NO3/c20-14-2-1-12-9-19-4-3-11-7-17-18(22-10-21-17)8-15(11)16(19)6-13(12)5-14/h1-2,5,7-8,16,20H,3-4,6,9-10H2 BJEUYJVVERSDAG-UHFFFAOYSA-N 50493349 CHEMBL2425377 D(2) dopamine receptor Rattus norvegicus 6918 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73356845 433960614 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199147 Oc1cc2CCN3Cc4c(O)cccc4CC3c2cc1O InChI=1S/C17H17NO3/c19-15-3-1-2-10-6-14-12-8-17(21)16(20)7-11(12)4-5-18(14)9-13(10)15/h1-3,7-8,14,19-21H,4-6,9H2 SJCUJBCYBXGZOY-UHFFFAOYSA-N 50493355 CHEMBL2425376 D(2) dopamine receptor Rattus norvegicus 85 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708127 433960620 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199148 COc1ccc2CN3CCc4cc5OCOc5cc4C3Cc2c1 InChI=1S/C19H19NO3/c1-21-15-3-2-13-10-20-5-4-12-8-18-19(23-11-22-18)9-16(12)17(20)7-14(13)6-15/h2-3,6,8-9,17H,4-5,7,10-11H2,1H3 JSCUCCUETPUNRT-UHFFFAOYSA-N 50493356 CHEMBL2425372 D(2) dopamine receptor Rattus norvegicus 1148 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708061 433960621 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199149 Oc1ccc2CN3CCc4cc(Cl)c(O)cc4C3Cc2c1 InChI=1S/C17H16ClNO2/c18-15-6-10-3-4-19-9-11-1-2-13(20)5-12(11)7-16(19)14(10)8-17(15)21/h1-2,5-6,8,16,20-21H,3-4,7,9H2 CJOFMPAUHPDCBS-UHFFFAOYSA-N 50493357 CHEMBL2425369 D(2) dopamine receptor Rattus norvegicus 186 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493357&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708059 433960622 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199155 COc1ccc2CN3CCc4cc(OCc5ccccc5)c(OCc5ccccc5)cc4C3Cc2c1 InChI=1S/C32H31NO3/c1-34-28-13-12-26-20-33-15-14-25-18-31(35-21-23-8-4-2-5-9-23)32(36-22-24-10-6-3-7-11-24)19-29(25)30(33)17-27(26)16-28/h2-13,16,18-19,30H,14-15,17,20-22H2,1H3 URBGRKGOMMSWMO-UHFFFAOYSA-N 50493353 CHEMBL2425370 D(2) dopamine receptor Rattus norvegicus 41687 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493353 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493353&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708060 433960618 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199157 Oc1ccc2CN3CCc4cc5OCOc5cc4C3Cc2c1 InChI=1S/C18H17NO3/c20-14-2-1-12-9-19-4-3-11-7-17-18(22-10-21-17)8-15(11)16(19)6-13(12)5-14/h1-2,5,7-8,16,20H,3-4,6,9-10H2 BJEUYJVVERSDAG-UHFFFAOYSA-N 50493349 CHEMBL2425377 D(2) dopamine receptor Rattus norvegicus 7506 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73356845 433960614 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199158 COc1ccc2CN3CCc4cc(O)c(O)cc4C3Cc2c1 InChI=1S/C18H19NO3/c1-22-14-3-2-12-10-19-5-4-11-8-17(20)18(21)9-15(11)16(19)7-13(12)6-14/h2-3,6,8-9,16,20-21H,4-5,7,10H2,1H3 QENRDSSNVLVQMF-UHFFFAOYSA-N 50493352 CHEMBL2425371 D(2) dopamine receptor Rattus norvegicus 74 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 71110301 433960617 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199161 COc1cccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc12 InChI=1S/C20H23NO3/c1-22-18-6-4-5-13-9-17-15-11-20(24-3)19(23-2)10-14(15)7-8-21(17)12-16(13)18/h4-6,10-11,17H,7-9,12H2,1-3H3 BIWCHVGMGDYNNS-UHFFFAOYSA-N 50493351 CHEMBL2425374 D(2) dopamine receptor Rattus norvegicus 363 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 57580939 433960616 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199162 COc1ccc2CN3CCc4cc(Cl)c(OC)cc4C3Cc2c1 InChI=1S/C19H20ClNO2/c1-22-15-4-3-13-11-21-6-5-12-8-17(20)19(23-2)10-16(12)18(21)9-14(13)7-15/h3-4,7-8,10,18H,5-6,9,11H2,1-2H3 MTAWQOIMTSBLBR-UHFFFAOYSA-N 50493354 CHEMBL2425368 D(2) dopamine receptor Rattus norvegicus 1995 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493354&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708058 433960619 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199164 Oc1cc2CCN3Cc4c(O)cccc4CC3c2cc1O InChI=1S/C17H17NO3/c19-15-3-1-2-10-6-14-12-8-17(21)16(20)7-11(12)4-5-18(14)9-13(10)15/h1-3,7-8,14,19-21H,4-6,9H2 SJCUJBCYBXGZOY-UHFFFAOYSA-N 50493355 CHEMBL2425376 D(2) dopamine receptor Rattus norvegicus 93 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493355&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708127 433960620 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199165 COc1ccc2CN3CCc4cc(OC)c(OC)cc4C3Cc2c1 InChI=1S/C20H23NO3/c1-22-16-5-4-14-12-21-7-6-13-10-19(23-2)20(24-3)11-17(13)18(21)9-15(14)8-16/h4-5,8,10-11,18H,6-7,9,12H2,1-3H3 HQWHBNSOZIKJSG-UHFFFAOYSA-N 50493358 CHEMBL2425373 D(2) dopamine receptor Rattus norvegicus 5120 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493358&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21119297 433960623 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199166 Oc1ccc2CN3CCc4cc(Cl)c(O)cc4C3Cc2c1 InChI=1S/C17H16ClNO2/c18-15-6-10-3-4-19-9-11-1-2-13(20)5-12(11)7-16(19)14(10)8-17(15)21/h1-2,5-6,8,16,20-21H,3-4,7,9H2 CJOFMPAUHPDCBS-UHFFFAOYSA-N 50493357 CHEMBL2425369 D(2) dopamine receptor Rattus norvegicus 188 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493357 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493357&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708059 433960622 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199170 Oc1cccc2CC3N(CCc4cc5OCOc5cc34)Cc12 InChI=1S/C18H17NO3/c20-16-3-1-2-11-6-15-13-8-18-17(21-10-22-18)7-12(13)4-5-19(15)9-14(11)16/h1-3,7-8,15,20H,4-6,9-10H2 VNNDXBUBKOYLIM-UHFFFAOYSA-N 50493350 CHEMBL2425378 D(2) dopamine receptor Rattus norvegicus 28 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708128 433960615 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199171 COc1ccc2CN3CCc4cc5OCOc5cc4C3Cc2c1 InChI=1S/C19H19NO3/c1-21-15-3-2-13-10-20-5-4-12-8-18-19(23-11-22-18)9-16(12)17(20)7-14(13)6-15/h2-3,6,8-9,17H,4-5,7,10-11H2,1H3 JSCUCCUETPUNRT-UHFFFAOYSA-N 50493356 CHEMBL2425372 D(2) dopamine receptor Rattus norvegicus 1140 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493356&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72708061 433960621 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51199174 COc1ccc2CN3CCc4cc(OC)c(OC)cc4C3Cc2c1 InChI=1S/C20H23NO3/c1-22-16-5-4-14-12-21-7-6-13-10-19(23-2)20(24-3)11-17(13)18(21)9-15(14)8-16/h4-5,8,10-11,18H,6-7,9,12H2,1-3H3 HQWHBNSOZIKJSG-UHFFFAOYSA-N 50493358 CHEMBL2425373 D(2) dopamine receptor Rattus norvegicus 5129 ChEMBL 10.1016/j.ejmech.2013.07.036 10.7270/Q2J1063R 23974015 Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D Universidad de Valencia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50493358 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50493358&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 21119297 433960623 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188299 O=c1[nH]c2cccc(N3CCN(Cc4ccccc4)CC3)c2[nH]1 InChI=1S/C18H20N4O/c23-18-19-15-7-4-8-16(17(15)20-18)22-11-9-21(10-12-22)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H2,19,20,23) MKJHGVZTPBBKML-UHFFFAOYSA-N 50071854 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL315864 D(2) dopamine receptor Rattus norvegicus 4.2 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18414156 103965564 CHEMBL315864 ZINC26648578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188319 Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-4-7-16(13-17)19-11-9-18(10-12-19)14-15-5-2-1-3-6-15/h1-8,13,20H,9-12,14H2 BISVFNHMXVNVMG-UHFFFAOYSA-N 50069907 1-benzyl-4-(3-hydroxyphenyl)piperazine::3-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL88365 D(2) dopamine receptor Rattus norvegicus 5.5 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015867 103963869 CHEMBL88365 ZINC26638652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188320 Clc1ccc2[nH]ccc2c1-[n+]1cc[n+](Cc2ccccc2)cc1 InChI=1S/C19H15ClN3/c20-17-6-7-18-16(8-9-21-18)19(17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-13H,14H2/q+1/p+1 NUZVTKAQWGCWOR-UHFFFAOYSA-O 50488614 CHEMBL2298810 D(2) dopamine receptor Rattus norvegicus 9.1 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76316875 433955879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188325 O=C1Cc2c(N1)cccc2N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H21N3O/c23-19-13-16-17(20-19)7-4-8-18(16)22-11-9-21(10-12-22)14-15-5-2-1-3-6-15/h1-8H,9-14H2,(H,20,23) TUVRDSTTWFDDHW-UHFFFAOYSA-N 50071856 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-indol-2-one::CHEMBL314952 D(2) dopamine receptor Rattus norvegicus 0.560000 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9995379 103965566 CHEMBL314952 ZINC26639952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188332 C(c1ccccc1)[n+]1cc[n+](cc1)-c1cccc2[nH]ccc12 InChI=1S/C19H16N3/c1-2-5-16(6-3-1)15-21-11-13-22(14-12-21)19-8-4-7-18-17(19)9-10-20-18/h1-14H,15H2/q+1/p+1 MDRPHHDESWTRFX-UHFFFAOYSA-O 50488615 CHEMBL2298808 D(2) dopamine receptor Rattus norvegicus 53 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488615&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76331467 433955880 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188369 Brc1ccc(-[n+]2cc[n+](Cc3ccccc3)cc2)c2cc[nH]c12 InChI=1S/C19H15BrN3/c20-17-6-7-18(16-8-9-21-19(16)17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-13H,14H2/q+1/p+1 XRQBUGNQFZLQGU-UHFFFAOYSA-O 50488601 CHEMBL2298809 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76320592 433955866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188373 O=C1Cc2c(N1)cccc2N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H21N3O/c23-19-13-16-17(20-19)7-4-8-18(16)22-11-9-21(10-12-22)14-15-5-2-1-3-6-15/h1-8H,9-14H2,(H,20,23) TUVRDSTTWFDDHW-UHFFFAOYSA-N 50071856 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-indol-2-one::CHEMBL314952 D(2) dopamine receptor Rattus norvegicus 8.1 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9995379 103965566 CHEMBL314952 ZINC26639952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188391 FC(F)(F)c1nc2c(cccc2[nH]1)-[n+]1cc[n+](Cc2ccccc2)cc1 InChI=1S/C19H14F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-12H,13H2/q+1/p+1 ZVPRVTLQVCJGOP-UHFFFAOYSA-O 50488618 CHEMBL2298812 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76309673 433955883 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188397 Clc1ccc2NC(=O)Cc2c1N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H20ClN3O/c20-16-6-7-17-15(12-18(24)21-17)19(16)23-10-8-22(9-11-23)13-14-4-2-1-3-5-14/h1-7H,8-13H2,(H,21,24) PIPVZEXRFVHTJJ-UHFFFAOYSA-N 50071859 4-(4-Benzyl-piperazin-1-yl)-5-chloro-1,3-dihydro-indol-2-one::CHEMBL330108 D(2) dopamine receptor Rattus norvegicus 403 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323780 103965569 CHEMBL330108 ZINC26645609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188399 C(c1ccccc1)[n+]1cc[n+](cc1)-c1cccc2[nH]cnc12 InChI=1S/C18H15N4/c1-2-5-15(6-3-1)13-21-9-11-22(12-10-21)17-8-4-7-16-18(17)20-14-19-16/h1-12,14H,13H2/q+1/p+1 NVMWQGNZMUKJTG-UHFFFAOYSA-O 50488636 CHEMBL2298811 D(2) dopamine receptor Rattus norvegicus 258 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76309672 433955901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188404 Clc1ccc2[nH]ccc2c1-[n+]1cc[n+](Cc2ccccc2)cc1 InChI=1S/C19H15ClN3/c20-17-6-7-18-16(8-9-21-18)19(17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-13H,14H2/q+1/p+1 NUZVTKAQWGCWOR-UHFFFAOYSA-O 50488614 CHEMBL2298810 D(2) dopamine receptor Rattus norvegicus 81 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76316875 433955879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188406 Clc1ccc2NC(=O)Cc2c1N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H20ClN3O/c20-16-6-7-17-15(12-18(24)21-17)19(16)23-10-8-22(9-11-23)13-14-4-2-1-3-5-14/h1-7H,8-13H2,(H,21,24) PIPVZEXRFVHTJJ-UHFFFAOYSA-N 50071859 4-(4-Benzyl-piperazin-1-yl)-5-chloro-1,3-dihydro-indol-2-one::CHEMBL330108 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323780 103965569 CHEMBL330108 ZINC26645609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188409 O=c1[nH]c2cccc(N3CCN(Cc4ccccc4)CC3)c2[nH]1 InChI=1S/C18H20N4O/c23-18-19-15-7-4-8-16(17(15)20-18)22-11-9-21(10-12-22)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H2,19,20,23) MKJHGVZTPBBKML-UHFFFAOYSA-N 50071854 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL315864 D(2) dopamine receptor Rattus norvegicus 46 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18414156 103965564 CHEMBL315864 ZINC26648578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188410 Clc1ccc2[nH]ccc2c1-[n+]1cc[n+](Cc2ccccc2)cc1 InChI=1S/C19H15ClN3/c20-17-6-7-18-16(8-9-21-18)19(17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-13H,14H2/q+1/p+1 NUZVTKAQWGCWOR-UHFFFAOYSA-O 50488614 CHEMBL2298810 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488614&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76316875 433955879 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188412 Brc1ccc(-[n+]2cc[n+](Cc3ccccc3)cc2)c2cc[nH]c12 InChI=1S/C19H15BrN3/c20-17-6-7-18(16-8-9-21-19(16)17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-13H,14H2/q+1/p+1 XRQBUGNQFZLQGU-UHFFFAOYSA-O 50488601 CHEMBL2298809 D(2) dopamine receptor Rattus norvegicus 27 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76320592 433955866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188414 C(c1ccccc1)[n+]1cc[n+](cc1)-c1cccc2[nH]ccc12 InChI=1S/C19H16N3/c1-2-5-16(6-3-1)15-21-11-13-22(14-12-21)19-8-4-7-18-17(19)9-10-20-18/h1-14H,15H2/q+1/p+1 MDRPHHDESWTRFX-UHFFFAOYSA-O 50488615 CHEMBL2298808 D(2) dopamine receptor Rattus norvegicus 17 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488615&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76331467 433955880 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188417 O=C1Cc2c(N1)cccc2N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H21N3O/c23-19-13-16-17(20-19)7-4-8-18(16)22-11-9-21(10-12-22)14-15-5-2-1-3-6-15/h1-8H,9-14H2,(H,20,23) TUVRDSTTWFDDHW-UHFFFAOYSA-N 50071856 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-indol-2-one::CHEMBL314952 D(2) dopamine receptor Rattus norvegicus 8.0 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071856&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9995379 103965566 CHEMBL314952 ZINC26639952 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188424 FC(F)(F)c1nc2c(cccc2[nH]1)-[n+]1cc[n+](Cc2ccccc2)cc1 InChI=1S/C19H14F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-12H,13H2/q+1/p+1 ZVPRVTLQVCJGOP-UHFFFAOYSA-O 50488618 CHEMBL2298812 D(2) dopamine receptor Rattus norvegicus 4.1 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76309673 433955883 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188431 Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-4-7-16(13-17)19-11-9-18(10-12-19)14-15-5-2-1-3-6-15/h1-8,13,20H,9-12,14H2 BISVFNHMXVNVMG-UHFFFAOYSA-N 50069907 1-benzyl-4-(3-hydroxyphenyl)piperazine::3-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL88365 D(2) dopamine receptor Rattus norvegicus 246 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015867 103963869 CHEMBL88365 ZINC26638652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188433 FC(F)(F)c1nc2c(cccc2[nH]1)-[n+]1cc[n+](Cc2ccccc2)cc1 InChI=1S/C19H14F3N4/c20-19(21,22)18-23-15-7-4-8-16(17(15)24-18)26-11-9-25(10-12-26)13-14-5-2-1-3-6-14/h1-12H,13H2/q+1/p+1 ZVPRVTLQVCJGOP-UHFFFAOYSA-O 50488618 CHEMBL2298812 D(2) dopamine receptor Rattus norvegicus 0.510000 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488618&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76309673 433955883 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188443 C(c1ccccc1)[n+]1cc[n+](cc1)-c1cccc2[nH]cnc12 InChI=1S/C18H15N4/c1-2-5-15(6-3-1)13-21-9-11-22(12-10-21)17-8-4-7-16-18(17)20-14-19-16/h1-12,14H,13H2/q+1/p+1 NVMWQGNZMUKJTG-UHFFFAOYSA-O 50488636 CHEMBL2298811 D(2) dopamine receptor Rattus norvegicus 107 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76309672 433955901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188444 Brc1ccc(-[n+]2cc[n+](Cc3ccccc3)cc2)c2cc[nH]c12 InChI=1S/C19H15BrN3/c20-17-6-7-18(16-8-9-21-19(16)17)23-12-10-22(11-13-23)14-15-4-2-1-3-5-15/h1-13H,14H2/q+1/p+1 XRQBUGNQFZLQGU-UHFFFAOYSA-O 50488601 CHEMBL2298809 D(2) dopamine receptor Rattus norvegicus 47 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488601&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76320592 433955866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188449 Clc1ccc2NC(=O)Cc2c1N1CCN(Cc2ccccc2)CC1 InChI=1S/C19H20ClN3O/c20-16-6-7-17-15(12-18(24)21-17)19(16)23-10-8-22(9-11-23)13-14-4-2-1-3-5-14/h1-7H,8-13H2,(H,21,24) PIPVZEXRFVHTJJ-UHFFFAOYSA-N 50071859 4-(4-Benzyl-piperazin-1-yl)-5-chloro-1,3-dihydro-indol-2-one::CHEMBL330108 D(2) dopamine receptor Rattus norvegicus 540 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071859&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 44323780 103965569 CHEMBL330108 ZINC26645609 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188450 C(c1ccccc1)[n+]1cc[n+](cc1)-c1cccc2[nH]ccc12 InChI=1S/C19H16N3/c1-2-5-16(6-3-1)15-21-11-13-22(14-12-21)19-8-4-7-18-17(19)9-10-20-18/h1-14H,15H2/q+1/p+1 MDRPHHDESWTRFX-UHFFFAOYSA-O 50488615 CHEMBL2298808 D(2) dopamine receptor Rattus norvegicus 3.2 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488615&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76331467 433955880 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188456 Oc1cccc(c1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C17H20N2O/c20-17-8-4-7-16(13-17)19-11-9-18(10-12-19)14-15-5-2-1-3-6-15/h1-8,13,20H,9-12,14H2 BISVFNHMXVNVMG-UHFFFAOYSA-N 50069907 1-benzyl-4-(3-hydroxyphenyl)piperazine::3-(4-Benzyl-piperazin-1-yl)-phenol::CHEMBL88365 D(2) dopamine receptor Rattus norvegicus 95 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069907&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10015867 103963869 CHEMBL88365 ZINC26638652 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188463 O=c1[nH]c2cccc(N3CCN(Cc4ccccc4)CC3)c2[nH]1 InChI=1S/C18H20N4O/c23-18-19-15-7-4-8-16(17(15)20-18)22-11-9-21(10-12-22)13-14-5-2-1-3-6-14/h1-8H,9-13H2,(H2,19,20,23) MKJHGVZTPBBKML-UHFFFAOYSA-N 50071854 4-(4-Benzyl-piperazin-1-yl)-1,3-dihydro-benzoimidazol-2-one::CHEMBL315864 D(2) dopamine receptor Rattus norvegicus 87 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50071854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50071854&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 18414156 103965564 CHEMBL315864 ZINC26648578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51188466 C(c1ccccc1)[n+]1cc[n+](cc1)-c1cccc2[nH]cnc12 InChI=1S/C18H15N4/c1-2-5-15(6-3-1)13-21-9-11-22(12-10-21)17-8-4-7-16-18(17)20-14-19-16/h1-12,14H,13H2/q+1/p+1 NVMWQGNZMUKJTG-UHFFFAOYSA-O 50488636 CHEMBL2298811 D(2) dopamine receptor Rattus norvegicus 9.7 ChEMBL 10.1007/s00044-012-0055-5 10.7270/Q2959MG8 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50488636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50488636&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 76309672 433955901 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197335 Clc1ccc(cc1)-n1cc(CCCCCN2CCN(CC2)c2ccccc2)cn1 InChI=1S/C24H29ClN4/c25-22-10-12-24(13-11-22)29-20-21(19-26-29)7-3-2-6-14-27-15-17-28(18-16-27)23-8-4-1-5-9-23/h1,4-5,8-13,19-20H,2-3,6-7,14-18H2 MKRMGDJUMMLQKR-UHFFFAOYSA-N 50492800 CHEMBL2414358 D(2) dopamine receptor Rattus norvegicus 490 ChEMBL 10.1016/j.ejmech.2013.05.027 10.7270/Q2514253 23792350 Pompeu, TE; Alves, FR; Figueiredo, CD; Antonio, CB; Herzfeldt, V; Moura, BC; Rates, SM; Barreiro, EJ; Fraga, CA; Noël, F Universidade Federal do Rio de Janeiro http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72205222 433960065 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197336 Clc1ccc(cc1)-n1cc(COCCCN2CCN(CC2)c2ccccc2)cn1 InChI=1S/C23H27ClN4O/c24-21-7-9-23(10-8-21)28-18-20(17-25-28)19-29-16-4-11-26-12-14-27(15-13-26)22-5-2-1-3-6-22/h1-3,5-10,17-18H,4,11-16,19H2 STBLFBLDGSWOEM-UHFFFAOYSA-N 50492798 CHEMBL2414355 D(2) dopamine receptor Rattus norvegicus 790 ChEMBL 10.1016/j.ejmech.2013.05.027 10.7270/Q2514253 23792350 Pompeu, TE; Alves, FR; Figueiredo, CD; Antonio, CB; Herzfeldt, V; Moura, BC; Rates, SM; Barreiro, EJ; Fraga, CA; Noël, F Universidade Federal do Rio de Janeiro http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492798&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72205044 433960063 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197337 Clc1ccc(cc1)-n1cc(COCCN2CCN(CC2)c2ccccc2)cn1 InChI=1S/C22H25ClN4O/c23-20-6-8-22(9-7-20)27-17-19(16-24-27)18-28-15-14-25-10-12-26(13-11-25)21-4-2-1-3-5-21/h1-9,16-17H,10-15,18H2 OATAFOSOEAZGEK-UHFFFAOYSA-N 50492799 CHEMBL2414354 D(2) dopamine receptor Rattus norvegicus 1900 ChEMBL 10.1016/j.ejmech.2013.05.027 10.7270/Q2514253 23792350 Pompeu, TE; Alves, FR; Figueiredo, CD; Antonio, CB; Herzfeldt, V; Moura, BC; Rates, SM; Barreiro, EJ; Fraga, CA; Noël, F Universidade Federal do Rio de Janeiro http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72205043 433960064 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197338 CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 QZUDBNBUXVUHMW-UHFFFAOYSA-N 50001884 2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone::3-Hydroxy-2-phenyl-propionic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester::3-chloro-6-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine (Clozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine( Clozepine )::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Ciozapine)::8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine(Clopazine)::8-chloro-11-(4-methyl-piperazin-1-yl)-10H-dibenzo[b,e][1,4]diazepine::8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine::CHEMBL42::CHEMBL538973::CLOZAPINE::CLOZAPINE, 8-CHLORO-11-(4-METHYL-PIPERAZIN-1-YL)-5H-DIBENZO[B,E][1,4]DIAZEPINE::CLOZARIL::HF 1854::US10167256, Clozapine::US10752588, Compound Clozapine::US11498896, Compound Clozapine D(2) dopamine receptor Rattus norvegicus 140 ChEMBL 10.1016/j.ejmech.2013.05.027 10.7270/Q2514253 23792350 Pompeu, TE; Alves, FR; Figueiredo, CD; Antonio, CB; Herzfeldt, V; Moura, BC; Rates, SM; Barreiro, EJ; Fraga, CA; Noël, F Universidade Federal do Rio de Janeiro http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001884&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 2818 103916251 3766 CHEMBL42CHEMBL538973 DB00363 38 C06924 ZINC19796155 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51197357 Clc1ccc(cc1)-n1cc(CCCN2CCN(CC2)c2ccccc2)cn1 InChI=1S/C22H25ClN4/c23-20-8-10-22(11-9-20)27-18-19(17-24-27)5-4-12-25-13-15-26(16-14-25)21-6-2-1-3-7-21/h1-3,6-11,17-18H,4-5,12-16H2 HIFJFKUAMBPYFD-UHFFFAOYSA-N 50492802 CHEMBL2414356 D(2) dopamine receptor Rattus norvegicus 680 ChEMBL 10.1016/j.ejmech.2013.05.027 10.7270/Q2514253 23792350 Pompeu, TE; Alves, FR; Figueiredo, CD; Antonio, CB; Herzfeldt, V; Moura, BC; Rates, SM; Barreiro, EJ; Fraga, CA; Noël, F Universidade Federal do Rio de Janeiro http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50492802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50492802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 72205045 433960067 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216338 OC(=O)C(F)(F)F.CCCN(CCN1CCN(Cc2c[nH]c3cccc(OC)c23)CC1)C1CCc2nc(N)sc2C1 InChI=1S/C26H38N6OS.C2HF3O2/c1-3-9-32(20-7-8-21-24(16-20)34-26(27)29-21)15-14-30-10-12-31(13-11-30)18-19-17-28-22-5-4-6-23(33-2)25(19)22;3-2(4,5)1(6)7/h4-6,17,20,28H,3,7-16,18H2,1-2H3,(H2,27,29);(H,6,7) UNMUNOGGXWMAOM-UHFFFAOYSA-N 50499866 CHEMBL3742273 D(2) dopamine receptor Rattus norvegicus 1883 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499866&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127039741 433911767 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216348 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 990 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216349 OC(=O)C(F)(F)F.Nc1nc2CC[C@@H](Cc2s1)N(CCN1CCN(CC1)c1ccc2cc[nH]c2c1Cl)CC#N InChI=1S/C23H28ClN7S.C2HF3O2/c24-21-19(4-1-16-5-7-27-22(16)21)31-13-10-29(11-14-31)9-12-30(8-6-25)17-2-3-18-20(15-17)32-23(26)28-18;3-2(4,5)1(6)7/h1,4-5,7,17,27H,2-3,8-15H2,(H2,26,28);(H,6,7)/t17-;/m0./s1 MBQJYUJUUCIPML-LMOVPXPDSA-N 50499869 CHEMBL3742140 D(2) dopamine receptor Rattus norvegicus 172 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499869&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127042372 433911770 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216350 OC(=O)C(F)(F)F.CCCN(CCN1CCN(CC1)c1cc(F)c2[nH]ccc2c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C24H33FN6S.C2HF3O2/c1-2-7-30(18-3-4-21-22(16-18)32-24(26)28-21)11-8-29-9-12-31(13-10-29)19-14-17-5-6-27-23(17)20(25)15-19;3-2(4,5)1(6)7/h5-6,14-15,18,27H,2-4,7-13,16H2,1H3,(H2,26,28);(H,6,7)/t18-;/m0./s1 XYHCKILSQLANQP-FERBBOLQSA-N 50499871 CHEMBL3740760 D(2) dopamine receptor Rattus norvegicus 156 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499871&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127042028 433911772 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216351 OC(=O)C(F)(F)F.CCCN(CCN1CCN(CC1)c1ccc2cc[nH]c2c1Cl)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C24H33ClN6S.C2HF3O2/c1-2-9-30(18-4-5-19-21(16-18)32-24(26)28-19)13-10-29-11-14-31(15-12-29)20-6-3-17-7-8-27-23(17)22(20)25;3-2(4,5)1(6)7/h3,6-8,18,27H,2,4-5,9-16H2,1H3,(H2,26,28);(H,6,7)/t18-;/m0./s1 SKLZAZBJAPMPHI-FERBBOLQSA-N 50499867 CHEMBL3740041 D(2) dopamine receptor Rattus norvegicus 16 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499867&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127039745 433911768 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216352 OC(=O)C(F)(F)F.CCCN(CCN1CCN(Cc2c[nH]c3ccc(OC)cc23)CC1)C1CCc2nc(N)sc2C1 InChI=1S/C26H38N6OS.C2HF3O2/c1-3-8-32(20-4-6-24-25(15-20)34-26(27)29-24)14-13-30-9-11-31(12-10-30)18-19-17-28-23-7-5-21(33-2)16-22(19)23;3-2(4,5)1(6)7/h5,7,16-17,20,28H,3-4,6,8-15,18H2,1-2H3,(H2,27,29);(H,6,7) PWNHFSBIYOLUKO-UHFFFAOYSA-N 50499872 CHEMBL3740474 D(2) dopamine receptor Rattus norvegicus 1636 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499872&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127042351 433911773 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216353 CCCN(CCC)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1 MDBWEQVKJDMEMK-AWEZNQCLSA-N 50115277 (2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2R,3S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-(-)-5-hydroxy-2-(N,N-di-n-propylamino)tetralin::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol.HCl::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL269004 D(2) dopamine receptor Rattus norvegicus 153 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11299620 104009254 CHEMBL269004 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216360 OC(=O)C(F)(F)F.CCCN(CCN1CCN(Cc2c[nH]c3ccc(Br)cc23)CC1)C1CCc2nc(N)sc2C1 InChI=1S/C25H35BrN6S.C2HF3O2/c1-2-7-32(20-4-6-23-24(15-20)33-25(27)29-23)13-12-30-8-10-31(11-9-30)17-18-16-28-22-5-3-19(26)14-21(18)22;3-2(4,5)1(6)7/h3,5,14,16,20,28H,2,4,6-13,15,17H2,1H3,(H2,27,29);(H,6,7) PEOOBDRKXRIHJA-UHFFFAOYSA-N 50499873 CHEMBL3742127 D(2) dopamine receptor Rattus norvegicus 376 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499873&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127042353 433911774 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216368 OC(=O)C(F)(F)F.Nc1nc2CC[C@@H](Cc2s1)N(CCN1CCN(CC1)c1ccc2[nH]ccc2c1Cl)CC#N InChI=1S/C23H28ClN7S.C2HF3O2/c24-22-17-5-7-27-18(17)3-4-20(22)31-13-10-29(11-14-31)9-12-30(8-6-25)16-1-2-19-21(15-16)32-23(26)28-19;3-2(4,5)1(6)7/h3-5,7,16,27H,1-2,8-15H2,(H2,26,28);(H,6,7)/t16-;/m0./s1 DBPJWAZLNMDUCJ-NTISSMGPSA-N 50499870 CHEMBL3740778 D(2) dopamine receptor Rattus norvegicus 87 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499870&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127042371 433911771 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216369 OC(=O)C(F)(F)F.CCCN(CCN1CCN(CC1)c1c(Cl)ccc2[nH]ccc12)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C24H33ClN6S.C2HF3O2/c1-2-9-30(17-3-5-21-22(16-17)32-24(26)28-21)13-10-29-11-14-31(15-12-29)23-18-7-8-27-20(18)6-4-19(23)25;3-2(4,5)1(6)7/h4,6-8,17,27H,2-3,5,9-16H2,1H3,(H2,26,28);(H,6,7)/t17-;/m0./s1 FWMNUBBJKNQYHX-LMOVPXPDSA-N 50499868 CHEMBL3740286 D(2) dopamine receptor Rattus norvegicus 75 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499868&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127039746 433911769 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216370 OC(=O)C(F)(F)F.CCCN(CCN1CCN(Cc2c[nH]c3ccc(F)cc23)CC1)C1CCc2nc(N)sc2C1 InChI=1S/C25H35FN6S.C2HF3O2/c1-2-7-32(20-4-6-23-24(15-20)33-25(27)29-23)13-12-30-8-10-31(11-9-30)17-18-16-28-22-5-3-19(26)14-21(18)22;3-2(4,5)1(6)7/h3,5,14,16,20,28H,2,4,6-13,15,17H2,1H3,(H2,27,29);(H,6,7) JRYRIQZLHDAUMS-UHFFFAOYSA-N 50499874 CHEMBL3740143 D(2) dopamine receptor Rattus norvegicus 854 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499874&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127042355 433911775 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216374 OC(=O)C(F)(F)F.CCCN(CCN1CCN(Cc2c[nH]c3cccc(F)c23)CC1)C1CCc2nc(N)sc2C1 InChI=1S/C25H35FN6S.C2HF3O2/c1-2-8-32(19-6-7-21-23(15-19)33-25(27)29-21)14-13-30-9-11-31(12-10-30)17-18-16-28-22-5-3-4-20(26)24(18)22;3-2(4,5)1(6)7/h3-5,16,19,28H,2,6-15,17H2,1H3,(H2,27,29);(H,6,7) KXUNTUGQIFLWJN-UHFFFAOYSA-N 50499876 CHEMBL3740829 D(2) dopamine receptor Rattus norvegicus 992 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499876&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127039744 433911777 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51216378 OC(=O)C(F)(F)F.CCCN(CCN1CCN(Cc2c[nH]c3cccc(Cl)c23)CC1)C1CCc2nc(N)sc2C1 InChI=1S/C25H35ClN6S.C2HF3O2/c1-2-8-32(19-6-7-21-23(15-19)33-25(27)29-21)14-13-30-9-11-31(12-10-30)17-18-16-28-22-5-3-4-20(26)24(18)22;3-2(4,5)1(6)7/h3-5,16,19,28H,2,6-15,17H2,1H3,(H2,27,29);(H,6,7) KRUXDLAHBCTHHQ-UHFFFAOYSA-N 50499875 CHEMBL3741175 D(2) dopamine receptor Rattus norvegicus 1164 ChEMBL 10.1021/acs.jmedchem.5b01031 10.7270/Q2N019HB 26555041 Das, B; Vedachalam, S; Luo, D; Antonio, T; Reith, ME; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499875&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 127039743 433911776 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917760 CCn1ccc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2c1=O InChI=1S/C26H29N3O2S/c1-2-28-12-9-20-7-8-21(19-23(20)26(28)30)31-17-4-11-27-13-15-29(16-14-27)24-5-3-6-25-22(24)10-18-32-25/h3,5-10,12,18-19H,2,4,11,13-17H2,1H3 PDNXHLGRGCXECB-UHFFFAOYSA-N 194815 US9206167, 37::USRE48059, Compound of Example 37 D(2) dopamine receptor Rattus norvegicus 1.90 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194815&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885504 318150575 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917761 COc1ccc2ccn(CCCCN3CCN(CC3)c3cccc4sccc34)c(=O)c2c1 InChI=1S/C26H29N3O2S/c1-31-21-8-7-20-9-13-29(26(30)23(20)19-21)12-3-2-11-27-14-16-28(17-15-27)24-5-4-6-25-22(24)10-18-32-25/h4-10,13,18-19H,2-3,11-12,14-17H2,1H3 VNFXFHGUVVNZTJ-UHFFFAOYSA-N 194816 US9206167, 38::USRE48059, Compound of Example 38 D(2) dopamine receptor Rattus norvegicus 1.20 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194816&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66884823 318150576 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917762 Oc1ccc2ccn(CCCCN3CCN(CC3)c3cccc4sccc34)c(=O)c2c1 InChI=1S/C25H27N3O2S/c29-20-7-6-19-8-12-28(25(30)22(19)18-20)11-2-1-10-26-13-15-27(16-14-26)23-4-3-5-24-21(23)9-17-31-24/h3-9,12,17-18,29H,1-2,10-11,13-16H2 RHGQBJJYWPWFSG-UHFFFAOYSA-N 194817 US9206167, 39::USRE48059, Compound of Example 39 D(2) dopamine receptor Rattus norvegicus 1.20 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194817&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885761 318150577 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917763 O=c1[nH]ccc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc12 InChI=1S/C24H25N3O2S/c28-24-20-6-5-19(17-18(20)7-9-25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-21(22)8-16-30-23/h1,3-9,16-17H,2,10-15H2,(H,25,28) KFNYOATUSDCRLT-UHFFFAOYSA-N 194818 US9206167, 40::USRE48059, Compound of Example 40 D(2) dopamine receptor Rattus norvegicus 4.80 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194818&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 77162624 318150578 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917764 Cn1ccc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc2c1=O InChI=1S/C25H27N3O2S/c1-26-11-8-19-18-20(6-7-21(19)25(26)29)30-16-3-10-27-12-14-28(15-13-27)23-4-2-5-24-22(23)9-17-31-24/h2,4-9,11,17-18H,3,10,12-16H2,1H3 FQLPASRHPPCIMN-UHFFFAOYSA-N 194819 US9206167, 41::USRE48059, Compound of Example 41 D(2) dopamine receptor Rattus norvegicus 1.90 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194819&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885615 318150579 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917765 CC1CN(CCN1CCCOc1ccc2nc(=O)ccc2c1)c1cccc2sccc12 448321 USRE48059, Compound of Example 64 D(2) dopamine receptor Rattus norvegicus 3.20 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448321 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448321&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803093 440710331 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917766 CC1CN(CCN1CCCCOc1ccc2nc(=O)ccc2c1)c1cccc2sccc12 448322 USRE48059, Compound of Example 68 D(2) dopamine receptor Rattus norvegicus 1.000 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448322&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803094 440710332 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917767 CC1CN(CCN1CCCCOc1ccc2[nH]c(=O)ccc2c1)c1cccc2sccc12 448323 USRE48059, Compound of Example 69 D(2) dopamine receptor Rattus norvegicus 0.800 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448323 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448323&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803094 440710333 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917768 C(COc1ccc2ncccc2c1)CN1CCN(CC1)c1cccc2sccc12 InChI=1S/C24H25N3OS/c1-5-23(21-9-17-29-24(21)6-1)27-14-12-26(13-15-27)11-3-16-28-20-7-8-22-19(18-20)4-2-10-25-22/h1-2,4-10,17-18H,3,11-16H2 DOLKJSWXNRSFQR-UHFFFAOYSA-N 448324 USRE48059, Compound of Example 73::USRE48059, Compound of Example 84 D(2) dopamine receptor Rattus norvegicus 4.00 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803095 440710334 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917769 CC(=O)n1cccc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc12 448325 USRE48059, Compound of Example 79 D(2) dopamine receptor Rattus norvegicus 4.70 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448325 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448325&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803096 440710335 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917770 C(COc1ccc2cnccc2c1)CN1CCN(CC1)c1cccc2sccc12 InChI=1S/C24H25N3OS/c1-3-23(22-8-16-29-24(22)4-1)27-13-11-26(12-14-27)10-2-15-28-21-6-5-20-18-25-9-7-19(20)17-21/h1,3-9,16-18H,2,10-15H2 LCYHEEHACXNBDS-UHFFFAOYSA-N 448326 USRE48059, Compound of Example 80 D(2) dopamine receptor Rattus norvegicus 1.50 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448326 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448326&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803097 440710336 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917771 CC(=C)n1ccc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc2c1 448327 USRE48059, Compound of Example 81 D(2) dopamine receptor Rattus norvegicus 0.800 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448327 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448327&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803098 440710337 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917772 C(COc1ccc2ncccc2c1)CN1CCN(CC1)c1cccc2sccc12 InChI=1S/C24H25N3OS/c1-5-23(21-9-17-29-24(21)6-1)27-14-12-26(13-15-27)11-3-16-28-20-7-8-22-19(18-20)4-2-10-25-22/h1-2,4-10,17-18H,3,11-16H2 DOLKJSWXNRSFQR-UHFFFAOYSA-N 448324 USRE48059, Compound of Example 73::USRE48059, Compound of Example 84 D(2) dopamine receptor Rattus norvegicus 2.40 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448324&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803095 440710334 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917773 C(CCN1CCN(CC1)c1cccc2sccc12)COc1ccc2ncccc2c1 InChI=1S/C25H27N3OS/c1(2-17-29-21-8-9-23-20(19-21)5-4-11-26-23)12-27-13-15-28(16-14-27)24-6-3-7-25-22(24)10-18-30-25/h3-11,18-19H,1-2,12-17H2 NQADXPIUVOCEHC-UHFFFAOYSA-N 448329 USRE48059, Compound of Example 85 D(2) dopamine receptor Rattus norvegicus 2.00 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448329 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448329&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803099 440710338 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917774 CC(=O)N1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2C1 InChI=1S/C27H33N3O2S/c1-21(31)30-12-9-22-7-8-24(19-23(22)20-30)32-17-3-2-11-28-13-15-29(16-14-28)26-5-4-6-27-25(26)10-18-33-27/h4-8,10,18-19H,2-3,9,11-17,20H2,1H3 VYURXUBMJHIGDM-UHFFFAOYSA-N 448330 USRE48059, Compound of Example 90 D(2) dopamine receptor Rattus norvegicus 0.400 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803100 440710339 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917775 Fc1cc2CCNC(=O)c2cc1OCCCCN1CCN(CC1)c1cccc2sccc12 InChI=1S/C25H28FN3O2S/c26-21-16-18-6-8-27-25(30)20(18)17-23(21)31-14-2-1-9-28-10-12-29(13-11-28)22-4-3-5-24-19(22)7-15-32-24/h3-5,7,15-17H,1-2,6,8-14H2,(H,27,30) CMHYKJRULRYQDT-UHFFFAOYSA-N 448331 USRE48059, Compound of Example 91 D(2) dopamine receptor Rattus norvegicus 1.40 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448331&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803101 440710340 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917776 CN1CCc2cc(F)c(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O InChI=1S/C26H30FN3O2S/c1-28-10-7-19-17-22(27)24(18-21(19)26(28)31)32-15-3-2-9-29-11-13-30(14-12-29)23-5-4-6-25-20(23)8-16-33-25/h4-6,8,16-18H,2-3,7,9-15H2,1H3 LOCQPZLZRZUFCI-UHFFFAOYSA-N 448332 USRE48059, Compound of Example 92 D(2) dopamine receptor Rattus norvegicus 1.70 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448332&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803102 440710341 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917777 Cc1c(OCCCCN2CCN(CC2)c2cccc3sccc23)ccc2CCC(=O)Nc12 InChI=1S/C26H31N3O2S/c1-19-23(9-7-20-8-10-25(30)27-26(19)20)31-17-3-2-12-28-13-15-29(16-14-28)22-5-4-6-24-21(22)11-18-32-24/h4-7,9,11,18H,2-3,8,10,12-17H2,1H3,(H,27,30) MVUSQMRMHUPXSM-UHFFFAOYSA-N 448333 USRE48059, Compound of Example 116 D(2) dopamine receptor Rattus norvegicus 4.50 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448333&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803103 440710342 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917778 Cc1cccc2cc(OCCCCN3CCN(CC3)c3cccc4sccc34)c(=O)nc12 448334 USRE48059, Compound of Example 117 D(2) dopamine receptor Rattus norvegicus 4.70 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803104 440710343 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917779 Fc1cc(OCCCCN2CCN(CC2)c2cccc3sccc23)cc2ccc(=O)[nH]c12 InChI=1S/C25H26FN3O2S/c26-21-17-19(16-18-6-7-24(30)27-25(18)21)31-14-2-1-9-28-10-12-29(13-11-28)22-4-3-5-23-20(22)8-15-32-23/h3-8,15-17H,1-2,9-14H2,(H,27,30) OHNZSCWKWZLLOG-UHFFFAOYSA-N 194775 US9206167, 184::USRE48059, Compound of Example 118 D(2) dopamine receptor Rattus norvegicus 3.50 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194775 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194775&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172709 318150536 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917780 O=C1CCc2c(CCCN3CCN(CC3)c3cccc4sccc34)cccc2N1 InChI=1S/C24H27N3OS/c28-24-10-9-19-18(4-1-6-21(19)25-24)5-3-12-26-13-15-27(16-14-26)22-7-2-8-23-20(22)11-17-29-23/h1-2,4,6-8,11,17H,3,5,9-10,12-16H2,(H,25,28) VSFQKCMAABJTKS-UHFFFAOYSA-N 448336 USRE48059, Compound of Example 122 D(2) dopamine receptor Rattus norvegicus 3.30 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803106 440710345 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917781 CC(=O)Oc1ccc(CCCN2CCN(CC2)c2cccc3sccc23)c2NC(=O)CCc12 InChI=1S/C26H29N3O3S/c1-18(30)32-23-9-7-19(26-21(23)8-10-25(31)27-26)4-3-12-28-13-15-29(16-14-28)22-5-2-6-24-20(22)11-17-33-24/h2,5-7,9,11,17H,3-4,8,10,12-16H2,1H3,(H,27,31) RVIHBQPCNYIPAK-UHFFFAOYSA-N 448337 USRE48059, Compound of Example 128 D(2) dopamine receptor Rattus norvegicus 1.30 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803107 440710346 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917782 OCc1cc2CCC(=C)Nc2cc1CCCN1CCN(CC1)c1cccc2sccc12 InChI=1S/C26H31N3OS/c1-19-7-8-21-16-22(18-30)20(17-24(21)27-19)4-3-10-28-11-13-29(14-12-28)25-5-2-6-26-23(25)9-15-31-26/h2,5-6,9,15-17,27,30H,1,3-4,7-8,10-14,18H2 UGZUMCFREYJOCK-UHFFFAOYSA-N 448338 USRE48059, Compound of Example 139 D(2) dopamine receptor Rattus norvegicus 0.200 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803108 440710347 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917783 CC(=O)Nc1ccc(CCCN2CCN(CC2)c2cccc3sccc23)c2CCC(=O)Nc12 InChI=1S/C26H30N4O2S/c1-18(31)27-22-9-7-19(20-8-10-25(32)28-26(20)22)4-3-12-29-13-15-30(16-14-29)23-5-2-6-24-21(23)11-17-33-24/h2,5-7,9,11,17H,3-4,8,10,12-16H2,1H3,(H,27,31)(H,28,32) PUNFWZQMYYXCIF-UHFFFAOYSA-N 448339 USRE48059, Compound of Example 155 D(2) dopamine receptor Rattus norvegicus 2.30 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803109 440710348 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917784 Clc1cc2CCC(=C)Nc2c(Cl)c1CCCN1CCN(CC1)c1cccc2sccc12 InChI=1S/C25H27Cl2N3S/c1-17-7-8-18-16-21(26)19(24(27)25(18)28-17)4-3-10-29-11-13-30(14-12-29)22-5-2-6-23-20(22)9-15-31-23/h2,5-6,9,15-16,28H,1,3-4,7-8,10-14H2 IALCUIBHTWQWLY-UHFFFAOYSA-N 448341 USRE48059, Compound of Example 163 D(2) dopamine receptor Rattus norvegicus 2.80 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803110 440710350 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917785 Fc1cc(CCCN2CCN(CC2)c2cccc3sccc23)cc2CCC(=O)Nc12 InChI=1S/C24H26FN3OS/c25-20-16-17(15-18-6-7-23(29)26-24(18)20)3-2-9-27-10-12-28(13-11-27)21-4-1-5-22-19(21)8-14-30-22/h1,4-5,8,14-16H,2-3,6-7,9-13H2,(H,26,29) CZDWNVCYKSDREC-UHFFFAOYSA-N 448342 USRE48059, Compound of Example 184 D(2) dopamine receptor Rattus norvegicus 2.60 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803111 440710351 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917786 Cc1cc(=O)[nH]c2cccc(CCCN3CCN(CC3)c3cccc4sccc34)c12 InChI=1S/C25H27N3OS/c1-18-17-24(29)26-21-7-2-5-19(25(18)21)6-4-11-27-12-14-28(15-13-27)22-8-3-9-23-20(22)10-16-30-23/h2-3,5,7-10,16-17H,4,6,11-15H2,1H3,(H,26,29) PNRODQDBLAUTOA-UHFFFAOYSA-N 448343 USRE48059, Compound of Example 185 D(2) dopamine receptor Rattus norvegicus 2.70 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803112 440710352 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917787 O=C1CCc2cccc(CCCN3CCN(CC3)c3cccc4sccc34)c2N1 InChI=1S/C24H27N3OS/c28-23-10-9-19-5-1-4-18(24(19)25-23)6-3-12-26-13-15-27(16-14-26)21-7-2-8-22-20(21)11-17-29-22/h1-2,4-5,7-8,11,17H,3,6,9-10,12-16H2,(H,25,28) VLKQPXZUSZKIQY-UHFFFAOYSA-N 448344 USRE48059, Compound of Example 186 D(2) dopamine receptor Rattus norvegicus 2.30 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803113 440710353 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917788 O=c1ccc2c(CCCN3CCN(CC3)c3cccc4sccc34)cccc2[nH]1 InChI=1S/C24H25N3OS/c28-24-10-9-19-18(4-1-6-21(19)25-24)5-3-12-26-13-15-27(16-14-26)22-7-2-8-23-20(22)11-17-29-23/h1-2,4,6-11,17H,3,5,12-16H2,(H,25,28) RWPLJXDFGZBWQQ-UHFFFAOYSA-N 448345 USRE48059, Compound of Example 188 D(2) dopamine receptor Rattus norvegicus 1.60 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803114 440710354 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917789 Oc1ccc(CCCCN2CCN(CC2)c2cccc3sccc23)c2NC(=O)CCc12 InChI=1S/C25H29N3O2S/c29-22-9-7-18(25-20(22)8-10-24(30)26-25)4-1-2-12-27-13-15-28(16-14-27)21-5-3-6-23-19(21)11-17-31-23/h3,5-7,9,11,17,29H,1-2,4,8,10,12-16H2,(H,26,30) IZTBNQZNTWYNBZ-UHFFFAOYSA-N 448346 USRE48059, Compound of Example 190 D(2) dopamine receptor Rattus norvegicus 0.800 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=448346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=448346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155803115 440710355 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51223532 O=c1ccc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]1 InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-10,17-18H,1-2,11-16H2,(H,26,29) ZKIAIYBUSXZPLP-UHFFFAOYSA-N 194780 7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one::OPC 34712::Rexulti::US9206167, 1::USRE48059, Compound of Example 1::brexpiprazole D(2) dopamine receptor Rattus norvegicus 3.8 ChEMBL 10.1016/j.bmcl.2019.126667 10.7270/Q2FF3WM3 31547945 Kułaga, D; Jaśkowska, J; Satała, G Cracow University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194780&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73160133 318150541 DB09128 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917730 O=c1ccc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]1 InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-10,17-18H,1-2,11-16H2,(H,26,29) ZKIAIYBUSXZPLP-UHFFFAOYSA-N 194780 7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one::OPC 34712::Rexulti::US9206167, 1::USRE48059, Compound of Example 1::brexpiprazole D(2) dopamine receptor Rattus norvegicus 0.200 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194780&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73160133 318150541 DB09128 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917731 Cc1cc(=O)[nH]c2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc12 InChI=1S/C25H27N3O2S/c1-18-16-25(29)26-22-17-19(6-7-20(18)22)30-14-3-9-27-10-12-28(13-11-27)23-4-2-5-24-21(23)8-15-31-24/h2,4-8,15-17H,3,9-14H2,1H3,(H,26,29) KDRNGVINVOICBB-UHFFFAOYSA-N 194782 US9206167, 3::USRE48059, Compound of Example 3 D(2) dopamine receptor Rattus norvegicus 0.500 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194782&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 77162561 318150543 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917732 Cc1cc(=O)[nH]c2cc(OCCCCN3CCN(CC3)c3cccc4sccc34)ccc12 InChI=1S/C26H29N3O2S/c1-19-17-26(30)27-23-18-20(7-8-21(19)23)31-15-3-2-10-28-11-13-29(14-12-28)24-5-4-6-25-22(24)9-16-32-25/h4-9,16-18H,2-3,10-15H2,1H3,(H,27,30) UDHIXAYFUPCVNQ-UHFFFAOYSA-N 194783 US9206167, 4::USRE48059, Compound of Example 4 D(2) dopamine receptor Rattus norvegicus 0.500 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194783&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 77162627 318150544 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917733 Cc1cc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]c1=O InChI=1S/C25H27N3O2S/c1-18-16-19-6-7-20(17-22(19)26-25(18)29)30-14-3-9-27-10-12-28(13-11-27)23-4-2-5-24-21(23)8-15-31-24/h2,4-8,15-17H,3,9-14H2,1H3,(H,26,29) NHZKQPUHNXXGKW-UHFFFAOYSA-N 194784 US9206167, 5::USRE48059, Compound of Example 5 D(2) dopamine receptor Rattus norvegicus 0.600 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194784&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172714 318150545 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917734 Cc1cc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]c1=O InChI=1S/C26H29N3O2S/c1-19-17-20-7-8-21(18-23(20)27-26(19)30)31-15-3-2-10-28-11-13-29(14-12-28)24-5-4-6-25-22(24)9-16-32-25/h4-9,16-18H,2-3,10-15H2,1H3,(H,27,30) PHLDMSHQFGMHOE-UHFFFAOYSA-N 194785 US9206167, 6::USRE48059, Compound of Example 6 D(2) dopamine receptor Rattus norvegicus 0.800 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194785&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 74375865 318150546 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917735 O=c1ccc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2[nH]1 InChI=1S/C24H25N3O2S/c28-24-8-6-18-5-7-19(17-21(18)25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-20(22)9-16-30-23/h1,3-9,16-17H,2,10-15H2,(H,25,28) VDRZDRCYBDVYFF-UHFFFAOYSA-N 194786 US9206167, 7::USRE48059, Compound of Example 7 D(2) dopamine receptor Rattus norvegicus 0.500 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194786&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 73160134 318150547 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917736 O=C1CCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C24H27N3O2S/c28-24-8-6-18-5-7-19(17-21(18)25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-20(22)9-16-30-23/h1,3-5,7,9,16-17H,2,6,8,10-15H2,(H,25,28) OESURDJKQAMNOQ-UHFFFAOYSA-N 194789 US9206167, 10::USRE48059, Compound of Example 10 D(2) dopamine receptor Rattus norvegicus 0.400 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194789&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978815 318150550 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917737 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C25H29N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-6,8,10,17-18H,1-2,7,9,11-16H2,(H,26,29) LAWOHKNPRBDADQ-UHFFFAOYSA-N 194790 US9206167, 11::US9206167, 12::USRE48059, Compound of Example 12 D(2) dopamine receptor Rattus norvegicus 0.100 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11857245 318150551 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917738 O=C1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C25H29N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-6,8,10,17-18H,1-2,7,9,11-16H2,(H,26,29) LAWOHKNPRBDADQ-UHFFFAOYSA-N 194790 US9206167, 11::US9206167, 12::USRE48059, Compound of Example 12 D(2) dopamine receptor Rattus norvegicus 0.100 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11857245 318150551 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917739 O=C1CCc2ccc(OC\C=C/CN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h1-6,8,10,17-18H,7,9,11-16H2,(H,26,29)/b2-1- PFDUTSYNBVBRFL-UPHRSURJSA-N 194792 US9206167, 13::USRE48059, Compound of Example 13 D(2) dopamine receptor Rattus norvegicus 2.40 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24968724 318150552 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917740 CC(CCOc1ccc2CCC(=O)Nc2c1)CN1CCN(CC1)c1cccc2sccc12 InChI=1S/C26H31N3O2S/c1-19(9-15-31-21-7-5-20-6-8-26(30)27-23(20)17-21)18-28-11-13-29(14-12-28)24-3-2-4-25-22(24)10-16-32-25/h2-5,7,10,16-17,19H,6,8-9,11-15,18H2,1H3,(H,27,30) MAKRXTXQAUBBSF-UHFFFAOYSA-N 194793 US9206167, 14::USRE48059, Compound of Example 14 D(2) dopamine receptor Rattus norvegicus 3.20 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194793&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24968725 318150553 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917741 O=C1CCc2ccc(OC\C=C\CN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h1-6,8,10,17-18H,7,9,11-16H2,(H,26,29)/b2-1+ PFDUTSYNBVBRFL-OWOJBTEDSA-N 194794 US9206167, 15::USRE48059, Compound of Example 15 D(2) dopamine receptor Rattus norvegicus 0.200 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194794&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 24968726 318150554 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917742 CC1CC(=O)Nc2cc(OCCCCN3CCN(CC3)c3cccc4sccc34)ccc12 InChI=1S/C26H31N3O2S/c1-19-17-26(30)27-23-18-20(7-8-21(19)23)31-15-3-2-10-28-11-13-29(14-12-28)24-5-4-6-25-22(24)9-16-32-25/h4-9,16,18-19H,2-3,10-15,17H2,1H3,(H,27,30) FASXOXVOBCJFBS-UHFFFAOYSA-N 194795 US9206167, 16::USRE48059, Compound of Example 16 D(2) dopamine receptor Rattus norvegicus 0.700 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194795&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885300 318150555 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917743 O=C1CCc2ccc(OCCOCCN3CCN(CC3)c3cccc4sccc34)cc2N1 InChI=1S/C25H29N3O3S/c29-25-7-5-19-4-6-20(18-22(19)26-25)31-16-15-30-14-13-27-9-11-28(12-10-27)23-2-1-3-24-21(23)8-17-32-24/h1-4,6,8,17-18H,5,7,9-16H2,(H,26,29) MOISFIHQAJXBGP-UHFFFAOYSA-N 194796 US9206167, 17::USRE48059, Compound of Example 17 D(2) dopamine receptor Rattus norvegicus 2.20 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885287 318150556 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917744 CN1C(=O)CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc12 InChI=1S/C26H31N3O2S/c1-27-24-19-21(9-7-20(24)8-10-26(27)30)31-17-3-2-12-28-13-15-29(16-14-28)23-5-4-6-25-22(23)11-18-32-25/h4-7,9,11,18-19H,2-3,8,10,12-17H2,1H3 PUJLFURZMNJZQS-UHFFFAOYSA-N 194797 US9206167, 18::USRE48059, Compound of Example 18 D(2) dopamine receptor Rattus norvegicus 2.60 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978816 318150557 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917745 O=C1CCc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc2N1 InChI=1S/C24H27N3O2S/c28-24-8-5-18-17-19(6-7-21(18)25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-20(22)9-16-30-23/h1,3-4,6-7,9,16-17H,2,5,8,10-15H2,(H,25,28) SVNKBCHDVYMMAY-UHFFFAOYSA-N 194798 US9206167, 19::USRE48059, Compound of Example 19 D(2) dopamine receptor Rattus norvegicus 1.20 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194798&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978817 318150558 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917746 O=C1CCc2cc(OCCCCN3CCN(CC3)c3cccc4sccc34)ccc2N1 InChI=1S/C25H29N3O2S/c29-25-9-6-19-18-20(7-8-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-5,7-8,10,17-18H,1-2,6,9,11-16H2,(H,26,29) VPHRLRRZHMPEBH-UHFFFAOYSA-N 194799 US9206167, 20::USRE48059, Compound of Example 20 D(2) dopamine receptor Rattus norvegicus 1.50 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66886115 318150559 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917747 O=C1CCc2ccccc2N1CCCCCN1CCN(CC1)c1cccc2sccc12 InChI=1S/C26H31N3OS/c30-26-12-11-21-7-2-3-8-23(21)29(26)15-5-1-4-14-27-16-18-28(19-17-27)24-9-6-10-25-22(24)13-20-31-25/h2-3,6-10,13,20H,1,4-5,11-12,14-19H2 UYLAEYTXDWXVNM-UHFFFAOYSA-N 194801 US9206167, 22::USRE48059, Compound of Example 22 D(2) dopamine receptor Rattus norvegicus 4.00 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66884093 318150561 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917748 O=C1N(CCCCN2CCN(CC2)c2cccc3sccc23)CCc2ccccc12 InChI=1S/C25H29N3OS/c29-25-21-7-2-1-6-20(21)10-14-28(25)13-4-3-12-26-15-17-27(18-16-26)23-8-5-9-24-22(23)11-19-30-24/h1-2,5-9,11,19H,3-4,10,12-18H2 QZMDTGLDHUBNDE-UHFFFAOYSA-N 194802 US9206167, 23::USRE48059, Compound of Example 23 D(2) dopamine receptor Rattus norvegicus 0.700 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885601 318150562 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917749 O=C1N(CCCCCN2CCN(CC2)c2cccc3sccc23)CCc2ccccc12 InChI=1S/C26H31N3OS/c30-26-22-8-3-2-7-21(22)11-15-29(26)14-5-1-4-13-27-16-18-28(19-17-27)24-9-6-10-25-23(24)12-20-31-25/h2-3,6-10,12,20H,1,4-5,11,13-19H2 GNAVDNPHMGSLMD-UHFFFAOYSA-N 194803 US9206167, 24::USRE48059, Compound of Example 24 D(2) dopamine receptor Rattus norvegicus 5.00 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66884834 318150563 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917750 CN1CCc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc2C1=O InChI=1S/C25H29N3O2S/c1-26-11-8-19-18-20(6-7-21(19)25(26)29)30-16-3-10-27-12-14-28(15-13-27)23-4-2-5-24-22(23)9-17-31-24/h2,4-7,9,17-18H,3,8,10-16H2,1H3 XFIBBCPMZFVKIB-UHFFFAOYSA-N 194805 US9206167, 26::USRE48059, Compound of Example 26 D(2) dopamine receptor Rattus norvegicus 3.50 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194805&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885771 318150565 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917751 CCN1CCc2cc(OCCCN3CCN(CC3)c3cccc4sccc34)ccc2C1=O InChI=1S/C26H31N3O2S/c1-2-28-12-9-20-19-21(7-8-22(20)26(28)30)31-17-4-11-27-13-15-29(16-14-27)24-5-3-6-25-23(24)10-18-32-25/h3,5-8,10,18-19H,2,4,9,11-17H2,1H3 HGQRBZGJYMFYOO-UHFFFAOYSA-N 194806 US9206167, 27::USRE48059, Compound of Example 27 D(2) dopamine receptor Rattus norvegicus 4.90 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194806&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885975 318150566 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917752 O=C1NCCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc12 InChI=1S/C24H27N3O2S/c28-24-21-17-19(6-5-18(21)7-9-25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-20(22)8-16-30-23/h1,3-6,8,16-17H,2,7,9-15H2,(H,25,28) ZCVYWZZKFYUXJC-UHFFFAOYSA-N 194807 US10501452, Compound C::US9206167, 28::USRE48059, Compound of Example 28 D(2) dopamine receptor Rattus norvegicus 1.20 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194807&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978818 318150567 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917753 CN1CCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O InChI=1S/C25H29N3O2S/c1-26-11-8-19-6-7-20(18-22(19)25(26)29)30-16-3-10-27-12-14-28(15-13-27)23-4-2-5-24-21(23)9-17-31-24/h2,4-7,9,17-18H,3,8,10-16H2,1H3 RDOLSJCBVSDISX-UHFFFAOYSA-N 194808 US10501452, Compound B::US9206167, 30::USRE48059, Compound of Example 30 D(2) dopamine receptor Rattus norvegicus 0.700 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978936 318150568 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917754 CCN1CCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O InChI=1S/C26H31N3O2S/c1-2-28-12-9-20-7-8-21(19-23(20)26(28)30)31-17-4-11-27-13-15-29(16-14-27)24-5-3-6-25-22(24)10-18-32-25/h3,5-8,10,18-19H,2,4,9,11-17H2,1H3 HOTLVLKNIWVDRD-UHFFFAOYSA-N 194809 US9206167, 31::USRE48059, Compound of Example 31 D(2) dopamine receptor Rattus norvegicus 1.40 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885795 318150569 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917755 CN1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O InChI=1S/C26H31N3O2S/c1-27-12-9-20-7-8-21(19-23(20)26(27)30)31-17-3-2-11-28-13-15-29(16-14-28)24-5-4-6-25-22(24)10-18-32-25/h4-8,10,18-19H,2-3,9,11-17H2,1H3 IIQHIUSOYHIMSR-UHFFFAOYSA-N 194810 US9206167, 32::USRE48059, Compound of Example 32 D(2) dopamine receptor Rattus norvegicus 1.50 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978937 318150570 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917756 O=C1NCCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc12 InChI=1S/C25H29N3O2S/c29-25-22-18-20(7-6-19(22)8-10-26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)9-17-31-24/h3-7,9,17-18H,1-2,8,10-16H2,(H,26,29) JJQVVHYUPXCLCP-UHFFFAOYSA-N 194811 US9206167, 33::USRE48059, Compound of Example 33 D(2) dopamine receptor Rattus norvegicus 1.10 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194811&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978938 318150571 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917757 O=c1n(CCCCN2CCN(CC2)c2cccc3sccc23)ccc2ccccc12 InChI=1S/C25H27N3OS/c29-25-21-7-2-1-6-20(21)10-14-28(25)13-4-3-12-26-15-17-27(18-16-26)23-8-5-9-24-22(23)11-19-30-24/h1-2,5-11,14,19H,3-4,12-13,15-18H2 JYXRPFUZHOBUIE-UHFFFAOYSA-N 194812 US9206167, 34::USRE48059, Compound of Example 34 D(2) dopamine receptor Rattus norvegicus 1.20 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194812&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 66885503 318150572 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917758 O=c1[nH]ccc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc12 InChI=1S/C24H25N3O2S/c28-24-21-17-19(6-5-18(21)7-9-25-24)29-15-2-10-26-11-13-27(14-12-26)22-3-1-4-23-20(22)8-16-30-23/h1,3-9,16-17H,2,10-15H2,(H,25,28) KBDPNEXGRBZDFM-UHFFFAOYSA-N 194813 US9206167, 35::USRE48059, Compound of Example 35 D(2) dopamine receptor Rattus norvegicus 1.60 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 122172715 318150573 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 917759 Cn1ccc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2c1=O InChI=1S/C25H27N3O2S/c1-26-11-8-19-6-7-20(18-22(19)25(26)29)30-16-3-10-27-12-14-28(15-13-27)23-4-2-5-24-21(23)9-17-31-24/h2,4-9,11,17-18H,3,10,12-16H2,1H3 CVMRJJLVIWWJTQ-UHFFFAOYSA-N 194814 US9206167, 36::USRE48059, Compound of Example 36 D(2) dopamine receptor Rattus norvegicus 1.000 US Patent 10.7270/Q2833W3C aid1804519 USRE48059 Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T; Oshiro, Y; Taira, S Otsuka Pharmaceutical Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978940 318150574 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51282020 Fc1cccc(c1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24FN3O2S/c24-19-7-3-8-20(17-19)26-15-13-25(14-16-26)11-4-12-27-21-9-1-5-18-6-2-10-22(23(18)21)30(27,28)29/h1-3,5-10,17H,4,11-16H2 GZVYNCBPEHDVIB-UHFFFAOYSA-N 50010039 2-{3-[4-(3-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL415272 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2019.06.028 10.7270/Q20K2D06 31253535 Zaręba, P; Jaśkowska, J; Czekaj, I; Satała, G Cracow University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010039&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710729 103922967 CHEMBL415272 ZINC13823482 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51282034 Fc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24FN3O2S/c24-19-8-10-20(11-9-19)26-16-14-25(15-17-26)12-3-13-27-21-6-1-4-18-5-2-7-22(23(18)21)30(27,28)29/h1-2,4-11H,3,12-17H2 VGIGHGMPMUCLIQ-UHFFFAOYSA-N 50010044 2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide (Fenanserin)::2-{3-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide(Fananserin)::CHEMBL83894::ChEMBL_131689::FANANSERIN D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2019.06.028 10.7270/Q20K2D06 31253535 Zaręba, P; Jaśkowska, J; Czekaj, I; Satała, G Cracow University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010044&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60785 103922972 CHEMBL83894 5434 ZINC00597400 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51282035 Fc1ccccc1N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24FN3O2S/c24-19-8-1-2-9-20(19)26-16-14-25(15-17-26)12-5-13-27-21-10-3-6-18-7-4-11-22(23(18)21)30(27,28)29/h1-4,6-11H,5,12-17H2 RYQFNVDIVFBVPT-UHFFFAOYSA-N 50010047 2-{3-[4-(2-Fluoro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL83975 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2019.06.028 10.7270/Q20K2D06 31253535 Zaręba, P; Jaśkowska, J; Czekaj, I; Satała, G Cracow University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010047&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710728 103922975 CHEMBL83975 ZINC13823480 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51282036 Fc1ccc(cc1)N1CCN(CCCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C24H26FN3O2S/c25-20-9-11-21(12-10-20)27-17-15-26(16-18-27)13-1-2-14-28-22-7-3-5-19-6-4-8-23(24(19)22)31(28,29)30/h3-12H,1-2,13-18H2 ZRCNTFMWQUJZCU-UHFFFAOYSA-N 50010061 2-{4-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-butyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL82826 D(2) dopamine receptor Rattus norvegicus 300 ChEMBL 10.1016/j.bmc.2019.06.028 10.7270/Q20K2D06 31253535 Zaręba, P; Jaśkowska, J; Czekaj, I; Satała, G Cracow University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010061&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 15710741 103922989 CHEMBL82826 ZINC13823504 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51282128 Clc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24ClN3O2S/c24-19-8-10-20(11-9-19)26-16-14-25(15-17-26)12-3-13-27-21-6-1-4-18-5-2-7-22(23(18)21)30(27,28)29/h1-2,4-11H,3,12-17H2 CJJCHMQYAVQPOO-UHFFFAOYSA-N 50010042 2-{3-[4-(4-Chloro-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL83035 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2019.06.028 10.7270/Q20K2D06 31253535 Zaręba, P; Jaśkowska, J; Czekaj, I; Satała, G Cracow University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010042&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580036 103922970 CHEMBL83035 ZINC13823484 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51282133 Brc1ccc(cc1)N1CCN(CCCN2c3cccc4cccc(c34)S2(=O)=O)CC1 InChI=1S/C23H24BrN3O2S/c24-19-8-10-20(11-9-19)26-16-14-25(15-17-26)12-3-13-27-21-6-1-4-18-5-2-7-22(23(18)21)30(27,28)29/h1-2,4-11H,3,12-17H2 LGLMUFXNPSGLCJ-UHFFFAOYSA-N 50010045 2-{3-[4-(4-Bromo-phenyl)-piperazin-1-yl]-propyl}-2H-naphtho[1,8-cd]isothiazole 1,1-dioxide::CHEMBL83780 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.bmc.2019.06.028 10.7270/Q20K2D06 31253535 Zaręba, P; Jaśkowska, J; Czekaj, I; Satała, G Cracow University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50010045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50010045&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 14580038 103922973 CHEMBL83780 ZINC13823486 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51327315 CCCCCn1c2ccccc2n(CCCCN2CCN(CC2)c2ccc(F)cc2)c1=O InChI=1S/C26H35FN4O/c1-2-3-6-16-30-24-9-4-5-10-25(24)31(26(30)32)17-8-7-15-28-18-20-29(21-19-28)23-13-11-22(27)12-14-23/h4-5,9-14H,2-3,6-8,15-21H2,1H3 CYNRAFPHCBCEFW-UHFFFAOYSA-N 50536981 CHEMBL4577544 D(2) dopamine receptor Rattus norvegicus >1000 ChEMBL 10.1016/j.ejmech.2019.01.019 10.7270/Q2PG1W8C 30685525 Intagliata, S; Alsharif, WF; Mesangeau, C; Fazio, N; Seminerio, M; Xu, YT; Matsumoto, RR; McCurdy, CR University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50536981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50536981&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 58511881 440827805 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51327325 CCCn1c2ccccc2n(CCCCN2CCN(CC2)c2ccc(F)cc2)c1=O InChI=1S/C24H31FN4O/c1-2-13-28-22-7-3-4-8-23(22)29(24(28)30)15-6-5-14-26-16-18-27(19-17-26)21-11-9-20(25)10-12-21/h3-4,7-12H,2,5-6,13-19H2,1H3 OBZIHNKDBMLVDG-UHFFFAOYSA-N 50536985 CHEMBL4531345 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2019.01.019 10.7270/Q2PG1W8C 30685525 Intagliata, S; Alsharif, WF; Mesangeau, C; Fazio, N; Seminerio, M; Xu, YT; Matsumoto, RR; McCurdy, CR University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50536985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50536985&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 58511930 440827809 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51322189 CCN1CCC[C@H]1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 WAOQONBSWFLFPE-VIFPVBQESA-N 50005118 (S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::(S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide::(S)3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-((S)-1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide (raclopride)::3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide(Raclopride)::CHEMBL8809::RACLOPRIDE::Raclopride;3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxy-benzamide D(2) dopamine receptor Rattus norvegicus 1.2 ChEMBL 10.1016/j.bmc.2016.08.020 10.7270/Q20K2D23 27567078 Gibon, J; Kang, MS; Aliaga, A; Sharif, B; Rosa-Neto, P; Séguéla, P; Barker, PA; Kostikov, A University of British Columbia http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005118&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033769 103918664 CHEMBL8809 ZINC02021474 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319127 CCCN(CCCCCc1ccc(O)c(O)c1)C1CCc2nc(N)sc2C1 InChI=1S/C21H31N3O2S/c1-2-11-24(16-8-9-17-20(14-16)27-21(22)23-17)12-5-3-4-6-15-7-10-18(25)19(26)13-15/h7,10,13,16,25-26H,2-6,8-9,11-12,14H2,1H3,(H2,22,23) CVHFBMSYCSPBIQ-UHFFFAOYSA-N 50533793 CHEMBL4581614 D(2) dopamine receptor Rattus norvegicus 116 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533793&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90190962 440742375 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319128 CCCN(CCCc1ccc(O)c(OC)c1)C1CCc2nc(N)sc2C1 InChI=1S/C20H29N3O2S/c1-3-10-23(15-7-8-16-19(13-15)26-20(21)22-16)11-4-5-14-6-9-17(24)18(12-14)25-2/h6,9,12,15,24H,3-5,7-8,10-11,13H2,1-2H3,(H2,21,22) GKJWEBNCPUIVRF-UHFFFAOYSA-N 50533794 CHEMBL4549004 D(2) dopamine receptor Rattus norvegicus 2404 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533794&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118453658 440742376 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319129 NCCc1ccc(O)c(O)c1 InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 VYFYYTLLBUKUHU-UHFFFAOYSA-N 55121 3-HYDROXYTYRAMINE HYDROCHLORIDE::4-(2-aminoethyl)benzene-1,2-diol;hydrochloride::4-(2-aminoethyl)pyrocatechol;hydrochloride::4-(2-azanylethyl)benzene-1,2-diol;hydrochloride::Dopamine::MLS000069419::SMR000059081::cid_65340 D(2) dopamine receptor Rattus norvegicus 990 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search LDP 7PIM,5PAH,2VQ5,7LJD,6DYO,7F23,3NK2,4A7V,7F0T,7CWZ,6ZN2,5LOG,7CKZ,7X2F,5PHH,8EEJ,8EEG,7F24,6ZVP,4DU2,4DUB,2QMZ,2A3R,4XP1,4DTZ,7F1O,7F1Z 681 252635126 18243 DB00988 C03758 ZINC00033882 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319130 CCCN(CCCCCc1ccc(O)c(OC)c1)C1CCc2nc(N)sc2C1 InChI=1S/C22H33N3O2S/c1-3-12-25(17-9-10-18-21(15-17)28-22(23)24-18)13-6-4-5-7-16-8-11-19(26)20(14-16)27-2/h8,11,14,17,26H,3-7,9-10,12-13,15H2,1-2H3,(H2,23,24) PXPHOMJZPNVWMG-UHFFFAOYSA-N 50533795 CHEMBL4558954 D(2) dopamine receptor Rattus norvegicus 175 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533795&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118453657 440742377 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319131 CCCN(CCCCCc1ccc(O)c(O)c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C21H31N3O2S/c1-2-11-24(16-8-9-17-20(14-16)27-21(22)23-17)12-5-3-4-6-15-7-10-18(25)19(26)13-15/h7,10,13,16,25-26H,2-6,8-9,11-12,14H2,1H3,(H2,22,23)/t16-/m0/s1 CVHFBMSYCSPBIQ-INIZCTEOSA-N 50533796 CHEMBL4457171 D(2) dopamine receptor Rattus norvegicus 66 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533796&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155525527 440742378 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319132 CCCN(CCCCCc1cc(O)ccc1O)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C21H31N3O2S/c1-2-11-24(16-7-9-18-20(14-16)27-21(22)23-18)12-5-3-4-6-15-13-17(25)8-10-19(15)26/h8,10,13,16,25-26H,2-7,9,11-12,14H2,1H3,(H2,22,23)/t16-/m0/s1 KSDFLICEBJWAMA-INIZCTEOSA-N 50533791 CHEMBL4466245 D(2) dopamine receptor Rattus norvegicus 112 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533791&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155531663 440742373 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319133 CCCN(CCCCCc1ccc(O)c(O)c1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C24H33NO3/c1-2-14-25(20-11-12-21-19(17-20)8-6-9-22(21)26)15-5-3-4-7-18-10-13-23(27)24(28)16-18/h6,8-10,13,16,20,26-28H,2-5,7,11-12,14-15,17H2,1H3/t20-/m0/s1 TXJZKUBFJGPDAH-FQEVSTJZSA-N 50533790 CHEMBL4538230 D(2) dopamine receptor Rattus norvegicus 4.7 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533790&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 132578416 440742372 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319134 CCCN(CCCc1ccc(O)c(O)c1)C1CCc2nc(N)sc2C1 InChI=1S/C19H27N3O2S/c1-2-9-22(10-3-4-13-5-8-16(23)17(24)11-13)14-6-7-15-18(12-14)25-19(20)21-15/h5,8,11,14,23-24H,2-4,6-7,9-10,12H2,1H3,(H2,20,21) YBQDTFTUENERQZ-UHFFFAOYSA-N 50533797 CHEMBL4535068 D(2) dopamine receptor Rattus norvegicus 499 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533797&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155547944 440742379 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319135 CCCN(C\C=C\c1ccc(O)c(OC)c1)C1CCc2nc(N)sc2C1 InChI=1S/C20H27N3O2S/c1-3-10-23(15-7-8-16-19(13-15)26-20(21)22-16)11-4-5-14-6-9-17(24)18(12-14)25-2/h4-6,9,12,15,24H,3,7-8,10-11,13H2,1-2H3,(H2,21,22)/b5-4+ KMNNNCPLXWQXDG-SNAWJCMRSA-N 50533798 CHEMBL4593758 D(2) dopamine receptor Rattus norvegicus 4634 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533798&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118453663 440742380 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319148 CCCN(CCC\C=C\c1ccc(O)c(OC)c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C22H31N3O2S/c1-3-12-25(17-9-10-18-21(15-17)28-22(23)24-18)13-6-4-5-7-16-8-11-19(26)20(14-16)27-2/h5,7-8,11,14,17,26H,3-4,6,9-10,12-13,15H2,1-2H3,(H2,23,24)/b7-5+/t17-/m0/s1 DCTJWNXQZKKVMP-UABRLCRWSA-N 50533800 CHEMBL4573578 D(2) dopamine receptor Rattus norvegicus 123 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533800&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155563589 440742382 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319151 CCCN(CCC)C1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3 MDBWEQVKJDMEMK-UHFFFAOYSA-N 50020221 (-)-5-hydroxy-2-(dipropylamino)tetralin::(-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol::5-hydroxy-2-(dipropylamino)tetralin::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (DP-5-ADTN)::CHEMBL273273 D(2) dopamine receptor Rattus norvegicus 153 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020221&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 172267 103931135 CHEMBL273273 128 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319152 CCCN(CCCCCc1cc(O)ccc1O)C1CCc2nc(N)sc2C1 InChI=1S/C21H31N3O2S/c1-2-11-24(16-7-9-18-20(14-16)27-21(22)23-18)12-5-3-4-6-15-13-17(25)8-10-19(15)26/h8,10,13,16,25-26H,2-7,9,11-12,14H2,1H3,(H2,22,23) KSDFLICEBJWAMA-UHFFFAOYSA-N 50533802 CHEMBL4442119 D(2) dopamine receptor Rattus norvegicus 117 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533802&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118453654 440742384 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319153 CCCN(CCCCCCc1ccc(O)c(OC)c1)C1CCc2nc(N)sc2C1 InChI=1S/C23H35N3O2S/c1-3-13-26(18-10-11-19-22(16-18)29-23(24)25-19)14-7-5-4-6-8-17-9-12-20(27)21(15-17)28-2/h9,12,15,18,27H,3-8,10-11,13-14,16H2,1-2H3,(H2,24,25) SDBZJKFRYKEEMJ-UHFFFAOYSA-N 50533801 CHEMBL4535160 D(2) dopamine receptor Rattus norvegicus 59 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533801&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155547737 440742383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319162 CCCN(CCC\C=C\c1ccc(O)c(OC)c1)C1CCc2nc(N)sc2C1 InChI=1S/C22H31N3O2S/c1-3-12-25(17-9-10-18-21(15-17)28-22(23)24-18)13-6-4-5-7-16-8-11-19(26)20(14-16)27-2/h5,7-8,11,14,17,26H,3-4,6,9-10,12-13,15H2,1-2H3,(H2,23,24)/b7-5+ DCTJWNXQZKKVMP-FNORWQNLSA-N 50533803 CHEMBL4456350 D(2) dopamine receptor Rattus norvegicus 150 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533803&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118453652 440742385 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319165 CCCN(CCCCCc1ccc(O)c(OC)c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C22H33N3O2S/c1-3-12-25(17-9-10-18-21(15-17)28-22(23)24-18)13-6-4-5-7-16-8-11-19(26)20(14-16)27-2/h8,11,14,17,26H,3-7,9-10,12-13,15H2,1-2H3,(H2,23,24)/t17-/m0/s1 PXPHOMJZPNVWMG-KRWDZBQOSA-N 50533792 CHEMBL4452046 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533792&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 155522454 440742374 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51319167 CCCN(CCC\C=C/c1ccc(O)c(OC)c1)C1CCc2nc(N)sc2C1 InChI=1S/C22H31N3O2S/c1-3-12-25(17-9-10-18-21(15-17)28-22(23)24-18)13-6-4-5-7-16-8-11-19(26)20(14-16)27-2/h5,7-8,11,14,17,26H,3-4,6,9-10,12-13,15H2,1-2H3,(H2,23,24)/b7-5- DCTJWNXQZKKVMP-ALCCZGGFSA-N 50533799 CHEMBL4442437 D(2) dopamine receptor Rattus norvegicus 233 ChEMBL 10.1016/j.bmc.2016.08.021 10.7270/Q2B85CNF 27591013 Luo, D; Sharma, H; Yedlapudi, D; Antonio, T; Reith, MEA; Dutta, AK Wayne State University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50533799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50533799&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 118453650 440742381 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51297637 Clc1ccc(N2CCN(CCCCNC(=O)c3cc4ccccc4[nH]3)CC2)c(Cl)c1 InChI=1S/C23H26Cl2N4O/c24-18-7-8-22(19(25)16-18)29-13-11-28(12-14-29)10-4-3-9-26-23(30)21-15-17-5-1-2-6-20(17)27-21/h1-2,5-8,15-16,27H,3-4,9-14H2,(H,26,30) CYNHGJORJGHXEX-UHFFFAOYSA-N 50131925 1H-Indole-2-carboxylic acid {4-[4-(2,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL339960::N-(4-(4-(2,4-dichlorophenyl)piperazin-1-yl)butyl)-1H-indole-2-carboxamide D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2019.111674 10.7270/Q2FR012J 31518969 Grillo, A; Chemi, G; Brogi, S; Brindisi, M; Relitti, N; Fezza, F; Fazio, D; Castelletti, L; Perdona, E; Wong, A; Lamponi, S; Pecorelli, A; Benedusi, M; Fantacci, M; Valoti, M; Valacchi, G; Micheli, F; Novellino, E; Campiani, G; Butini, S; Maccarrone, M; Gemma, S University of Siena http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131925&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10411237 104022950 CHEMBL339960 ZINC03817191 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 987394 CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1Cl)C1CCc2c(O)cccc2C1 476245 6-((2-(4-(4-chloro-1H-indol-5-yl)piperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol::US10874669, Compound 12 D(2) dopamine receptor Rattus norvegicus 76.4 US Patent 10.7270/Q2FN198W aid1805111 US10874669 Dutta, AK WAYNE STATE UNIVERSITY http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476245&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 90190302 442076310 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 987388 CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1)C1CCc2nc(N)sc2C1 InChI=1S/C24H34N6S/c1-2-9-29(20-4-6-22-23(17-20)31-24(25)27-22)13-10-28-11-14-30(15-12-28)19-3-5-21-18(16-19)7-8-26-21/h3,5,7-8,16,20,26H,2,4,6,9-15,17H2,1H3,(H2,25,27) YQJXEYCSOAXZLM-UHFFFAOYSA-N 50392121 CHEMBL2152632::US10874669, Compound (+-)-10 D(2) dopamine receptor Rattus norvegicus 46.7 US Patent 10.7270/Q2FN198W aid1805111 US10874669 Dutta, AK WAYNE STATE UNIVERSITY http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392121&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60148498 163341145 CHEMBL2152632 ZINC95572455 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 987390 CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1)[C@@H]1CCc2nc(N)sc2C1 InChI=1S/C24H34N6S/c1-2-9-29(20-4-6-22-23(17-20)31-24(25)27-22)13-10-28-11-14-30(15-12-28)19-3-5-21-18(16-19)7-8-26-21/h3,5,7-8,16,20,26H,2,4,6,9-15,17H2,1H3,(H2,25,27)/t20-/m1/s1 YQJXEYCSOAXZLM-HXUWFJFHSA-N 50392123 CHEMBL2152634::US10874669, Compound (-)-10 D(2) dopamine receptor Rattus norvegicus 39.0 US Patent 10.7270/Q2FN198W aid1805111 US10874669 Dutta, AK WAYNE STATE UNIVERSITY http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392123&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60166104 163341147 CHEMBL2152634 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 987392 CCCN(CCN1CCN(CC1)c1ccc2[nH]ccc2c1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C24H34N6S/c1-2-9-29(20-4-6-22-23(17-20)31-24(25)27-22)13-10-28-11-14-30(15-12-28)19-3-5-21-18(16-19)7-8-26-21/h3,5,7-8,16,20,26H,2,4,6,9-15,17H2,1H3,(H2,25,27)/t20-/m0/s1 YQJXEYCSOAXZLM-FQEVSTJZSA-N 50392122 CHEMBL2152633::US10874669, Compound (+)-10 D(2) dopamine receptor Rattus norvegicus 134 US Patent 10.7270/Q2FN198W aid1805111 US10874669 Dutta, AK WAYNE STATE UNIVERSITY http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50392122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50392122&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 60148497 163341146 CHEMBL2152633 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51348367 O=C1[C@H]2[C@@H]3CC[C@@H](C3)[C@H]2C(=O)N1C[C@@H]1CCCC[C@H]1CN1CCN(CC1)c1nsc2ccccc12 InChI=1S/C28H36N4O2S/c33-27-24-18-9-10-19(15-18)25(24)28(34)32(27)17-21-6-2-1-5-20(21)16-30-11-13-31(14-12-30)26-22-7-3-4-8-23(22)35-29-26/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2/t18-,19+,20-,21-,24+,25-/m0/s1 PQXKDMSYBGKCJA-CVTJIBDQSA-N 85222 CAS_441351-20-8::Lurasidone::SM 13496 D(2) dopamine receptor Rattus norvegicus 1.7 ChEMBL 10.1016/j.bmc.2020.115459 10.7270/Q2D50RJB 32247749 Zaręba, P; Drabczyk, AK; Jaśkowska, J; Satała, G Cracow University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=85222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=85222&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 213046 136351322 70735 DB08815 ZINC33974796 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381208 O=C(NC1CC2CCC(C1)N2Cc1ccncc1)c1ccc2ccccc2c1 InChI=1S/C24H25N3O/c28-24(20-6-5-18-3-1-2-4-19(18)13-20)26-21-14-22-7-8-23(15-21)27(22)16-17-9-11-25-12-10-17/h1-6,9-13,21-23H,7-8,14-16H2,(H,26,28) KRKMBTPLHFDXGY-UHFFFAOYSA-N 50558330 CHEMBL4747071 D(2) dopamine receptor Rattus norvegicus 2700 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558330&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162650451 461828722 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381209 O=C(NC1CC2CCC(C1)N2Cc1cccnc1)c1ccc2ccccc2c1 InChI=1S/C24H25N3O/c28-24(20-8-7-18-5-1-2-6-19(18)12-20)26-21-13-22-9-10-23(14-21)27(22)16-17-4-3-11-25-15-17/h1-8,11-12,15,21-23H,9-10,13-14,16H2,(H,26,28) GAXNFSNKLNLTML-UHFFFAOYSA-N 50558331 CHEMBL4753691 D(2) dopamine receptor Rattus norvegicus 2400 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558331&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162653774 461828723 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381210 O=C(NC1CC2CCC(C1)N2Cc1ccccn1)c1ccc2ccccc2c1 InChI=1S/C24H25N3O/c28-24(19-9-8-17-5-1-2-6-18(17)13-19)26-21-14-22-10-11-23(15-21)27(22)16-20-7-3-4-12-25-20/h1-9,12-13,21-23H,10-11,14-16H2,(H,26,28) MXIKPNWJFPZIEG-UHFFFAOYSA-N 50558332 CHEMBL4751499 D(2) dopamine receptor Rattus norvegicus 2200 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558332&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162652129 461828724 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381211 FC(F)(F)c1ccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)cc1 InChI=1S/C26H25F3N2O/c27-26(28,29)21-9-5-17(6-10-21)16-31-23-11-12-24(31)15-22(14-23)30-25(32)20-8-7-18-3-1-2-4-19(18)13-20/h1-10,13,22-24H,11-12,14-16H2,(H,30,32) VOIWMCKLADJVNH-UHFFFAOYSA-N 50558333 CHEMBL4798573 D(2) dopamine receptor Rattus norvegicus 629 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558333 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558333&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162674639 461828725 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381212 FC(F)(F)c1cccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)c1 InChI=1S/C26H25F3N2O/c27-26(28,29)21-7-3-4-17(12-21)16-31-23-10-11-24(31)15-22(14-23)30-25(32)20-9-8-18-5-1-2-6-19(18)13-20/h1-9,12-13,22-24H,10-11,14-16H2,(H,30,32) WMOUNTYQKVWKLT-UHFFFAOYSA-N 50558334 CHEMBL4789287 D(2) dopamine receptor Rattus norvegicus 217 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558334&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162669328 461828726 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381213 FC(F)(F)c1ccccc1CN1C2CCC1CC(C2)NC(=O)c1ccc2ccccc2c1 InChI=1S/C26H25F3N2O/c27-26(28,29)24-8-4-3-7-20(24)16-31-22-11-12-23(31)15-21(14-22)30-25(32)19-10-9-17-5-1-2-6-18(17)13-19/h1-10,13,21-23H,11-12,14-16H2,(H,30,32) JWPZUFWVTLYATO-UHFFFAOYSA-N 50558335 CHEMBL4792888 D(2) dopamine receptor Rattus norvegicus 537 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558335&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162671014 461828727 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381214 Fc1ccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)cc1 InChI=1S/C25H25FN2O/c26-21-9-5-17(6-10-21)16-28-23-11-12-24(28)15-22(14-23)27-25(29)20-8-7-18-3-1-2-4-19(18)13-20/h1-10,13,22-24H,11-12,14-16H2,(H,27,29) SATYUJPMEVIREP-UHFFFAOYSA-N 50558336 CHEMBL4794055 D(2) dopamine receptor Rattus norvegicus 137 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558336 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558336&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 132991899 461828728 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381215 Fc1cccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)c1 InChI=1S/C25H25FN2O/c26-21-7-3-4-17(12-21)16-28-23-10-11-24(28)15-22(14-23)27-25(29)20-9-8-18-5-1-2-6-19(18)13-20/h1-9,12-13,22-24H,10-11,14-16H2,(H,27,29) PEUBRJWCXGVXAM-UHFFFAOYSA-N 50558337 CHEMBL4787037 D(2) dopamine receptor Rattus norvegicus 214 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558337 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558337&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 132991898 461828729 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381216 Fc1ccccc1CN1C2CCC1CC(C2)NC(=O)c1ccc2ccccc2c1 InChI=1S/C25H25FN2O/c26-24-8-4-3-7-20(24)16-28-22-11-12-23(28)15-21(14-22)27-25(29)19-10-9-17-5-1-2-6-18(17)13-19/h1-10,13,21-23H,11-12,14-16H2,(H,27,29) CXOSZPBZRSVJMM-UHFFFAOYSA-N 50558338 CHEMBL4757614 D(2) dopamine receptor Rattus norvegicus 715 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558338 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558338&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162656499 461828730 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381217 Brc1ccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)cc1 InChI=1S/C25H25BrN2O/c26-21-9-5-17(6-10-21)16-28-23-11-12-24(28)15-22(14-23)27-25(29)20-8-7-18-3-1-2-4-19(18)13-20/h1-10,13,22-24H,11-12,14-16H2,(H,27,29) MVALOOQKEWOVOD-UHFFFAOYSA-N 50558339 CHEMBL4744722 D(2) dopamine receptor Rattus norvegicus 4.5 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558339 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558339&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162648506 461828731 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381218 Brc1cccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)c1 InChI=1S/C25H25BrN2O/c26-21-7-3-4-17(12-21)16-28-23-10-11-24(28)15-22(14-23)27-25(29)20-9-8-18-5-1-2-6-19(18)13-20/h1-9,12-13,22-24H,10-11,14-16H2,(H,27,29) CVNMEGDKYDEZEZ-UHFFFAOYSA-N 50558340 CHEMBL4752931 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558340&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162653243 461828732 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381219 Brc1ccccc1CN1C2CCC1CC(C2)NC(=O)c1ccc2ccccc2c1 InChI=1S/C25H25BrN2O/c26-24-8-4-3-7-20(24)16-28-22-11-12-23(28)15-21(14-22)27-25(29)19-10-9-17-5-1-2-6-18(17)13-19/h1-10,13,21-23H,11-12,14-16H2,(H,27,29) XSYSNNYCAGTQIS-UHFFFAOYSA-N 50558341 CHEMBL4786672 D(2) dopamine receptor Rattus norvegicus 23 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558341&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162667804 461828733 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381220 Clc1ccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)cc1 InChI=1S/C25H25ClN2O/c26-21-9-5-17(6-10-21)16-28-23-11-12-24(28)15-22(14-23)27-25(29)20-8-7-18-3-1-2-4-19(18)13-20/h1-10,13,22-24H,11-12,14-16H2,(H,27,29) YSRMSDOOKMXUGR-UHFFFAOYSA-N 50558342 CHEMBL4754231 D(2) dopamine receptor Rattus norvegicus 0.400000 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558342&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162654869 461828734 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381221 Clc1cccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)c1 InChI=1S/C25H25ClN2O/c26-21-7-3-4-17(12-21)16-28-23-10-11-24(28)15-22(14-23)27-25(29)20-9-8-18-5-1-2-6-19(18)13-20/h1-9,12-13,22-24H,10-11,14-16H2,(H,27,29) LPXFEDNRALTDRP-UHFFFAOYSA-N 50558343 CHEMBL4748723 D(2) dopamine receptor Rattus norvegicus 3.6 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558343&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162650325 461828735 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381222 Clc1ccccc1CN1C2CCC1CC(C2)NC(=O)c1ccc2ccccc2c1 InChI=1S/C25H25ClN2O/c26-24-8-4-3-7-20(24)16-28-22-11-12-23(28)15-21(14-22)27-25(29)19-10-9-17-5-1-2-6-18(17)13-19/h1-10,13,21-23H,11-12,14-16H2,(H,27,29) SYXLHZUPFGBLKA-UHFFFAOYSA-N 50558344 CHEMBL4788272 D(2) dopamine receptor Rattus norvegicus 35 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558344&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162668738 461828736 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381223 COc1ccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)cc1 InChI=1S/C26H28N2O2/c1-30-25-12-6-18(7-13-25)17-28-23-10-11-24(28)16-22(15-23)27-26(29)21-9-8-19-4-2-3-5-20(19)14-21/h2-9,12-14,22-24H,10-11,15-17H2,1H3,(H,27,29) WRTDTGCYNXJBFL-UHFFFAOYSA-N 50558345 CHEMBL4788843 D(2) dopamine receptor Rattus norvegicus 0.600000 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558345&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162669420 461828737 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381224 COc1cccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)c1 InChI=1S/C26H28N2O2/c1-30-25-8-4-5-18(13-25)17-28-23-11-12-24(28)16-22(15-23)27-26(29)21-10-9-19-6-2-3-7-20(19)14-21/h2-10,13-14,22-24H,11-12,15-17H2,1H3,(H,27,29) VUVINUKZJWGVMG-UHFFFAOYSA-N 50558346 CHEMBL4746049 D(2) dopamine receptor Rattus norvegicus 26 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558346&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162647871 461828738 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381225 COc1ccccc1CN1C2CCC1CC(C2)NC(=O)c1ccc2ccccc2c1 InChI=1S/C26H28N2O2/c1-30-25-9-5-4-8-21(25)17-28-23-12-13-24(28)16-22(15-23)27-26(29)20-11-10-18-6-2-3-7-19(18)14-20/h2-11,14,22-24H,12-13,15-17H2,1H3,(H,27,29) FXOIOAMUXOSCPC-UHFFFAOYSA-N 50558347 CHEMBL4785742 D(2) dopamine receptor Rattus norvegicus 77 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558347&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162668081 461828739 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381226 Cc1ccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)cc1 InChI=1S/C26H28N2O/c1-18-6-8-19(9-7-18)17-28-24-12-13-25(28)16-23(15-24)27-26(29)22-11-10-20-4-2-3-5-21(20)14-22/h2-11,14,23-25H,12-13,15-17H2,1H3,(H,27,29) HZBJZVMDTJBVGG-UHFFFAOYSA-N 50558348 CHEMBL4743158 D(2) dopamine receptor Rattus norvegicus 0.400000 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558348 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558348&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162645822 461828740 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381227 Cc1cccc(CN2C3CCC2CC(C3)NC(=O)c2ccc3ccccc3c2)c1 InChI=1S/C26H28N2O/c1-18-5-4-6-19(13-18)17-28-24-11-12-25(28)16-23(15-24)27-26(29)22-10-9-20-7-2-3-8-21(20)14-22/h2-10,13-14,23-25H,11-12,15-17H2,1H3,(H,27,29) VNSXPWKNFNCOAO-UHFFFAOYSA-N 50558349 CHEMBL4764971 D(2) dopamine receptor Rattus norvegicus 3.3 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558349&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162661136 461828741 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381228 Cc1ccccc1CN1C2CCC1CC(C2)NC(=O)c1ccc2ccccc2c1 InChI=1S/C26H28N2O/c1-18-6-2-3-9-22(18)17-28-24-12-13-25(28)16-23(15-24)27-26(29)21-11-10-19-7-4-5-8-20(19)14-21/h2-11,14,23-25H,12-13,15-17H2,1H3,(H,27,29) WAPWCWXQGLXTRS-UHFFFAOYSA-N 50558350 CHEMBL4760235 D(2) dopamine receptor Rattus norvegicus 118 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558350 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558350&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162657511 461828742 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381229 COc1cc(nc2ccccc12)C(=O)NC1CC2CCC(C1)N2Cc1ccccc1 InChI=1S/C25H27N3O2/c1-30-24-15-23(27-22-10-6-5-9-21(22)24)25(29)26-18-13-19-11-12-20(14-18)28(19)16-17-7-3-2-4-8-17/h2-10,15,18-20H,11-14,16H2,1H3,(H,26,29) GAAFXVBYENZECG-UHFFFAOYSA-N 50558351 CHEMBL4793624 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558351&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162672333 461828743 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51381230 O=C(NC1CC2CCC(C1)N2Cc1ccccc1)c1ccc2ccccc2n1 InChI=1S/C24H25N3O/c28-24(23-13-10-18-8-4-5-9-22(18)26-23)25-19-14-20-11-12-21(15-19)27(20)16-17-6-2-1-3-7-17/h1-10,13,19-21H,11-12,14-16H2,(H,25,28) JAINGJLAHUUKKM-UHFFFAOYSA-N 50558352 CHEMBL4748538 D(2) dopamine receptor Rattus norvegicus 589 ChEMBL 10.1016/j.bmc.2016.06.038 10.7270/Q2Q52T9K 27377863 Stefanowicz, J; Słowiński, T; Wróbel, MZ; Herold, F; Gomółka, AE; Wesołowska, A; Jastrzębska-Więsek, M; Partyka, A; Andres-Mach, M; Czuczwar, SJ; Łuszczki, JJ; Zagaja, M; Siwek, A; Nowak, G; Żołnierek, M; Bączek, T; Ulenberg, S; Belka, M; Turło, J Medical University of Warsaw http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50558352 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50558352&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162650181 461828744 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375239 CN1CCc2ccc(OCCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2C1=O InChI=1S/C26H30FN3O3/c1-29-12-8-18-4-6-21(17-23(18)26(29)31)32-15-3-2-11-30-13-9-19(10-14-30)25-22-7-5-20(27)16-24(22)33-28-25/h4-7,16-17,19H,2-3,8-15H2,1H3 AZMODJDXZVARNU-UHFFFAOYSA-N 423295 US10501452, Compound 1 D(2) dopamine receptor Rattus norvegicus 42 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423295 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423295&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339860 434149089 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375240 CN1CCc2ccc(OCCCCN3CCN(CC3)c3cccc(Cl)c3Cl)cc2C1=O InChI=1S/C24H29Cl2N3O2/c1-27-11-9-18-7-8-19(17-20(18)24(27)30)31-16-3-2-10-28-12-14-29(15-13-28)22-6-4-5-21(25)23(22)26/h4-8,17H,2-3,9-16H2,1H3 NVFPJOVGMQRLJI-UHFFFAOYSA-N 50556096 CHEMBL4759887 D(2) dopamine receptor Rattus norvegicus 316 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556096&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162657377 461694864 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375241 CN1CCc2ccc(OCCCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)cc2C1=O InChI=1S/C25H30F3N3O2/c1-29-11-9-19-7-8-22(18-23(19)24(29)32)33-16-3-2-10-30-12-14-31(15-13-30)21-6-4-5-20(17-21)25(26,27)28/h4-8,17-18H,2-3,9-16H2,1H3 NWSWBVKRQJZUCZ-UHFFFAOYSA-N 423297 US10501452, Compound 3 D(2) dopamine receptor Rattus norvegicus 261 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423297 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423297&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339846 434149091 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375242 COc1ccccc1N1CCN(CCCCOc2ccc3CCN(C)C(=O)c3c2)CC1 InChI=1S/C25H33N3O3/c1-26-13-11-20-9-10-21(19-22(20)25(26)29)31-18-6-5-12-27-14-16-28(17-15-27)23-7-3-4-8-24(23)30-2/h3-4,7-10,19H,5-6,11-18H2,1-2H3 YCZWURFQDCDNKN-UHFFFAOYSA-N 423296 US10501452, Compound 2 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423296 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423296&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339814 434149090 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375243 CC1CCc2ccc(OCCCCN3CCC(CC3)c3nsc4ccccc34)cc2C1=O InChI=1S/C27H32N2O2S/c1-19-8-9-20-10-11-22(18-24(20)27(19)30)31-17-5-4-14-29-15-12-21(13-16-29)26-23-6-2-3-7-25(23)32-28-26/h2-3,6-7,10-11,18-19,21H,4-5,8-9,12-17H2,1H3 MCVRDRSJDMMPFB-UHFFFAOYSA-N 50556097 CHEMBL4751120 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556097&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162652014 461694865 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375244 CN1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O InChI=1S/C26H31N3O2S/c1-27-12-9-20-7-8-21(19-23(20)26(27)30)31-17-3-2-11-28-13-15-29(16-14-28)24-5-4-6-25-22(24)10-18-32-25/h4-8,10,18-19H,2-3,9,11-17H2,1H3 IIQHIUSOYHIMSR-UHFFFAOYSA-N 194810 US9206167, 32::USRE48059, Compound of Example 32 D(2) dopamine receptor Rattus norvegicus 162 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194810&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978937 318150570 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375245 Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 RAPZEAPATHNIPO-UHFFFAOYSA-N 50001885 (risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::1-(2-Allyl-phenoxy)-3-isopropylamino-propan-2-ol::2-(2-(4-(benzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-7,8,9,9a-tetrahydro-1H-pyrido[1,2-a]pyrimidin-4(6H)-one::2-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-6,7,8,8a-tetrahydro-5H-naphthalen-1-one::3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (Resperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one (risperidone)::3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-ethyl}-2-methyl-6,7,8,9-tetrahydro-pyrido[1,2-a]pyrimidin-4-one(risperidone)::5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-ethyl]-6-methyl-1,3-dihydro-indol-2-one(Norastemizole)::CHEMBL85::R 64 766::RISPERDAL::RISPERIDONE::US10167256, Risperidone::US10174011, risperidone::US10259786, Risperidone::US10501452, Compound risperidone::US8802672, Risperidone::WO2023288027, Cmpd Risperidone D(2) dopamine receptor Rattus norvegicus 3.7 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001885&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 8NU 6A93,6CM4 5073 103916252 8871 CHEMBL85 DB00734 96 ZINC00538312 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375246 Clc1cccc(N2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29) CEUORZQYGODEFX-UHFFFAOYSA-N 50130293 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one::ARIPIPRAZOLE::CHEMBL1112::US10174011, aripiprazole::US10752588, Compound Aripiprazole::US11498896, Compound Aripiprazole::US9018213, aripprazole::US9156822, Aripiprazole D(2) dopamine receptor Rattus norvegicus 9.7 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50130293 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50130293&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 9SC 7VR9,7E2Z,6A7P,7VOE,7WKZ 60795 104021727 31236 CHEMBL1112 DB01238 34 C12564 ZINC01851149 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375247 CN1CCc2ccc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2C1=O InChI=1S/C25H28FN3O3/c1-28-11-7-17-3-5-20(16-22(17)25(28)30)31-14-2-10-29-12-8-18(9-13-29)24-21-6-4-19(26)15-23(21)32-27-24/h3-6,15-16,18H,2,7-14H2,1H3 RDGPIFCCGRDXMY-UHFFFAOYSA-N 423299 US10501452, Compound 5 D(2) dopamine receptor Rattus norvegicus 6.9 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423299&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339817 434149093 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375248 CN1CCc2ccc(OCCCN3CCC(CC3)C(=O)c3ccc(F)cc3F)cc2C1=O InChI=1S/C25H28F2N2O3/c1-28-11-7-17-3-5-20(16-22(17)25(28)31)32-14-2-10-29-12-8-18(9-13-29)24(30)21-6-4-19(26)15-23(21)27/h3-6,15-16,18H,2,7-14H2,1H3 CGLXSIVRMNIRPK-UHFFFAOYSA-N 50556098 CHEMBL4754923 D(2) dopamine receptor Rattus norvegicus 902 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556098&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162654732 461694866 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375249 CN1CCc2ccc(OCCCN3CCN(CC3)c3cccc(c3)C(F)(F)F)cc2C1=O InChI=1S/C24H28F3N3O2/c1-28-10-8-18-6-7-21(17-22(18)23(28)31)32-15-3-9-29-11-13-30(14-12-29)20-5-2-4-19(16-20)24(25,26)27/h2,4-7,16-17H,3,8-15H2,1H3 OHRZGEKCBGRRIB-UHFFFAOYSA-N 50556099 CHEMBL4779075 D(2) dopamine receptor Rattus norvegicus 123 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556099&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162663239 461694867 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375250 CN1CCc2ccc(OCCCN3CCC(CC3)c3nsc4ccccc34)cc2C1=O InChI=1S/C25H29N3O2S/c1-27-13-9-18-7-8-20(17-22(18)25(27)29)30-16-4-12-28-14-10-19(11-15-28)24-21-5-2-3-6-23(21)31-26-24/h2-3,5-8,17,19H,4,9-16H2,1H3 WTAGZKRPXFDEPO-UHFFFAOYSA-N 50556100 CHEMBL4741087 D(2) dopamine receptor Rattus norvegicus 923 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556100&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162646030 461694868 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375251 CN1CCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O InChI=1S/C25H29N3O2S/c1-26-11-8-19-6-7-20(18-22(19)25(26)29)30-16-3-10-27-12-14-28(15-13-27)23-4-2-5-24-21(23)9-17-31-24/h2,4-7,9,17-18H,3,8,10-16H2,1H3 RDOLSJCBVSDISX-UHFFFAOYSA-N 194808 US10501452, Compound B::US9206167, 30::USRE48059, Compound of Example 30 D(2) dopamine receptor Rattus norvegicus 29 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=194808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=194808&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11978936 318150568 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375252 CN1CCc2ccc(OCCCN3CCN(Cc4ccc5OCOc5c4)CC3)cc2C1=O InChI=1S/C25H31N3O4/c1-26-9-7-20-4-5-21(16-22(20)25(26)29)30-14-2-8-27-10-12-28(13-11-27)17-19-3-6-23-24(15-19)32-18-31-23/h3-6,15-16H,2,7-14,17-18H2,1H3 WUPATJHWIBFKHY-UHFFFAOYSA-N 50556101 CHEMBL4795287 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556101&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162672669 461694869 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375253 CN1CCc2ccc(OCCCN3CCN(CC3)c3ccc4ccccc4n3)cc2C1=O InChI=1S/C26H30N4O2/c1-28-13-11-20-7-9-22(19-23(20)26(28)31)32-18-4-12-29-14-16-30(17-15-29)25-10-8-21-5-2-3-6-24(21)27-25/h2-3,5-10,19H,4,11-18H2,1H3 VFDLYPNEKROUJA-UHFFFAOYSA-N 423309 US10501452, Compound 15 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423309 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423309&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339847 434149103 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375254 CN1CCc2ccc(OCCCN3CCN(CC3)c3ccccc3)cc2C1=O InChI=1S/C23H29N3O2/c1-24-12-10-19-8-9-21(18-22(19)23(24)27)28-17-5-11-25-13-15-26(16-14-25)20-6-3-2-4-7-20/h2-4,6-9,18H,5,10-17H2,1H3 SJQGLRPDBHCHCW-UHFFFAOYSA-N 423310 US10501452, Compound 16 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423310&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339870 434149104 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375255 CN1CCc2ccc(OCCCN3CCN(CC3)c3ccccn3)cc2C1=O InChI=1S/C22H28N4O2/c1-24-11-8-18-6-7-19(17-20(18)22(24)27)28-16-4-10-25-12-14-26(15-13-25)21-5-2-3-9-23-21/h2-3,5-7,9,17H,4,8,10-16H2,1H3 JLHMEGWPLLZUIA-UHFFFAOYSA-N 423317 US10501452, Compound 23 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423317&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339857 434149111 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375256 CN1CCc2ccc(OCCCN3CCN(CC3)c3ncccn3)cc2C1=O InChI=1S/C21H27N5O2/c1-24-10-6-17-4-5-18(16-19(17)20(24)27)28-15-3-9-25-11-13-26(14-12-25)21-22-7-2-8-23-21/h2,4-5,7-8,16H,3,6,9-15H2,1H3 SKUUWDIJGSUACY-UHFFFAOYSA-N 423318 US10501452, Compound 24 D(2) dopamine receptor Rattus norvegicus 1368 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423318&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339834 434149112 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375257 CN1CCc2ccc(OCCCN3CCN(CC3)c3ccccc3Cl)cc2C1=O InChI=1S/C23H28ClN3O2/c1-25-11-9-18-7-8-19(17-20(18)23(25)28)29-16-4-10-26-12-14-27(15-13-26)22-6-3-2-5-21(22)24/h2-3,5-8,17H,4,9-16H2,1H3 QIMOBLHMKZLPIE-UHFFFAOYSA-N 423312 US10501452, Compound 18 D(2) dopamine receptor Rattus norvegicus 391 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423312&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339850 434149106 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375258 CN1CCc2ccc(OCCCN3CCN(CC3)c3ccc(Cl)cc3)cc2C1=O InChI=1S/C23H28ClN3O2/c1-25-11-9-18-3-8-21(17-22(18)23(25)28)29-16-2-10-26-12-14-27(15-13-26)20-6-4-19(24)5-7-20/h3-8,17H,2,9-16H2,1H3 OFNWXXGHORGIMJ-UHFFFAOYSA-N 423311 US10501452, Compound 17 D(2) dopamine receptor Rattus norvegicus 268 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423311&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339858 434149105 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375259 CN1CCc2ccc(OCCCN3CCN(CC3)c3cccc(Cl)c3Cl)cc2C1=O InChI=1S/C23H27Cl2N3O2/c1-26-10-8-17-6-7-18(16-19(17)23(26)29)30-15-3-9-27-11-13-28(14-12-27)21-5-2-4-20(24)22(21)25/h2,4-7,16H,3,8-15H2,1H3 GEUHNGSPHVYFJW-UHFFFAOYSA-N 50556102 CHEMBL4749019 D(2) dopamine receptor Rattus norvegicus 68 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556102&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162649601 461694870 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375260 CN1CCc2ccc(OCCCN3CCN(CC3)c3ccccc3F)cc2C1=O InChI=1S/C23H28FN3O2/c1-25-11-9-18-7-8-19(17-20(18)23(25)28)29-16-4-10-26-12-14-27(15-13-26)22-6-3-2-5-21(22)24/h2-3,5-8,17H,4,9-16H2,1H3 JSYJUUGAOMCCSL-UHFFFAOYSA-N 423314 US10501452, Compound 20 D(2) dopamine receptor Rattus norvegicus 117 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423314&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339838 434149108 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375261 CN1CCc2ccc(OCCCN3CCN(CC3)c3ccc(F)cc3)cc2C1=O InChI=1S/C23H28FN3O2/c1-25-11-9-18-3-8-21(17-22(18)23(25)28)29-16-2-10-26-12-14-27(15-13-26)20-6-4-19(24)5-7-20/h3-8,17H,2,9-16H2,1H3 RMXGCHHYNPXIEU-UHFFFAOYSA-N 423313 US10501452, Compound 19 D(2) dopamine receptor Rattus norvegicus 532 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423313&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339869 434149107 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375262 COc1ccc(cc1)N1CCN(CCCOc2ccc3CCN(C)C(=O)c3c2)CC1 InChI=1S/C24H31N3O3/c1-25-12-10-19-4-7-22(18-23(19)24(25)28)30-17-3-11-26-13-15-27(16-14-26)20-5-8-21(29-2)9-6-20/h4-9,18H,3,10-17H2,1-2H3 AXTPDHOKNPRWNN-UHFFFAOYSA-N 423315 US10501452, Compound 21 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423315&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135375002 434149109 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375263 COc1ccccc1N1CCN(CCCOc2ccc3CCN(C)C(=O)c3c2)CC1 InChI=1S/C24H31N3O3/c1-25-12-10-19-8-9-20(18-21(19)24(25)28)30-17-5-11-26-13-15-27(16-14-26)22-6-3-4-7-23(22)29-2/h3-4,6-9,18H,5,10-17H2,1-2H3 SLPNWORIUMAUFP-UHFFFAOYSA-N 423316 US10501452, Compound 22 D(2) dopamine receptor Rattus norvegicus 896 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423316&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135375223 434149110 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375264 CN1CCc2ccc(OCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2C1=O InChI=1S/C24H26FN3O3/c1-27-9-6-16-2-4-19(15-21(16)24(27)29)30-13-12-28-10-7-17(8-11-28)23-20-5-3-18(25)14-22(20)31-26-23/h2-5,14-15,17H,6-13H2,1H3 SXVOZULUNOLYBU-UHFFFAOYSA-N 50556103 CHEMBL4742251 D(2) dopamine receptor Rattus norvegicus 568 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556103&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162645951 461694871 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375265 CN1CCc2ccc(OCC(O)CN3CCC(CC3)c3noc4cc(F)ccc34)cc2C1=O InChI=1S/C25H28FN3O4/c1-28-9-6-16-2-4-20(13-22(16)25(28)31)32-15-19(30)14-29-10-7-17(8-11-29)24-21-5-3-18(26)12-23(21)33-27-24/h2-5,12-13,17,19,30H,6-11,14-15H2,1H3 BCMNXZCLONGCPJ-UHFFFAOYSA-N 423298 US10501452, Compound 4 D(2) dopamine receptor Rattus norvegicus 1237 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423298 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423298&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339862 434149092 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375266 CN1CCc2ccc(OCC(F)CN3CCC(CC3)c3noc4cc(F)ccc34)cc2C1=O InChI=1S/C25H27F2N3O3/c1-29-9-6-16-2-4-20(13-22(16)25(29)31)32-15-19(27)14-30-10-7-17(8-11-30)24-21-5-3-18(26)12-23(21)33-28-24/h2-5,12-13,17,19H,6-11,14-15H2,1H3 UHXLNPJTNXHHQF-UHFFFAOYSA-N 50556104 CHEMBL4790565 D(2) dopamine receptor Rattus norvegicus 359 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556104&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162671608 461694872 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375267 CCN1CCc2ccc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2C1=O InChI=1S/C26H30FN3O3/c1-2-30-14-10-18-4-6-21(17-23(18)26(30)31)32-15-3-11-29-12-8-19(9-13-29)25-22-7-5-20(27)16-24(22)33-28-25/h4-7,16-17,19H,2-3,8-15H2,1H3 NGSZJZCWVNVBQV-UHFFFAOYSA-N 423301 US10501452, Compound 7 D(2) dopamine receptor Rattus norvegicus 249 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423301 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423301&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339856 434149095 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375268 Cn1ccc2ccc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2c1=O InChI=1S/C25H26FN3O3/c1-28-11-7-17-3-5-20(16-22(17)25(28)30)31-14-2-10-29-12-8-18(9-13-29)24-21-6-4-19(26)15-23(21)32-27-24/h3-7,11,15-16,18H,2,8-10,12-14H2,1H3 XJPFLUQFOAAHFE-UHFFFAOYSA-N 50556105 CHEMBL4743324 D(2) dopamine receptor Rattus norvegicus 9.2 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556105&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 154956306 461694873 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375269 CN1COc2ccc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)cc2C1=O InChI=1S/C24H26FN3O4/c1-27-15-31-21-6-4-18(14-20(21)24(27)29)30-12-2-9-28-10-7-16(8-11-28)23-19-5-3-17(25)13-22(19)32-26-23/h3-6,13-14,16H,2,7-12,15H2,1H3 KDMVVQOQEKIXTC-UHFFFAOYSA-N 423305 US10501452, Compound 11 D(2) dopamine receptor Rattus norvegicus 698 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=423305 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=423305&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135339849 434149099 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51375270 CN1CCc2cc(OCCCN3CCC(CC3)c3noc4cc(F)ccc34)ccc2C1=O InChI=1S/C25H28FN3O3/c1-28-11-7-18-15-20(4-6-21(18)25(28)30)31-14-2-10-29-12-8-17(9-13-29)24-22-5-3-19(26)16-23(22)32-27-24/h3-6,15-17H,2,7-14H2,1H3 UIQNRXMEDLWYLV-UHFFFAOYSA-N 50556106 CHEMBL4758213 D(2) dopamine receptor Rattus norvegicus >10000 ChEMBL 10.1016/j.ejmech.2020.112709 10.7270/Q2XK8K6M 32877805 Jin, J; Zhang, K; Dou, F; Hao, C; Zhang, Y; Cao, X; Gao, L; Xiong, J; Liu, X; Liu, BF; Zhang, G; Chen, Y Jiangsu Ocean University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50556106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50556106&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 162656281 461694874 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51361380 CCCC(CCC)C(=O)OC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1 InChI=1S/C29H39ClFNO3/c1-3-6-23(7-4-2)28(33)35-27(22-9-15-26(31)16-10-22)8-5-19-32-20-17-29(34,18-21-32)24-11-13-25(30)14-12-24/h9-16,23,27,34H,3-8,17-21H2,1-2H3 ZMMTZQWVQFDIBG-UHFFFAOYSA-N 50550237 CHEMBL4747257 D(2) dopamine receptor Rattus norvegicus >5000 ChEMBL 10.1021/acs.jmedchem.6b01039 10.7270/Q2RR22W8 27739690 Olivieri, M; Amata, E; Vinciguerra, S; Fiorito, J; Giurdanella, G; Drago, F; Caporarello, N; Prezzavento, O; Arena, E; Salerno, L; Rescifina, A; Lupo, G; Anfuso, CD; Marrazzo, A University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50550237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50550237&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 132598366 461680577 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51361381 OC(CCCN1CCC(O)(CC1)c1ccc(Cl)cc1)c1ccc(F)cc1 InChI=1S/C21H25ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,20,25-26H,1-2,11-15H2 WNZBBTJFOIOEMP-UHFFFAOYSA-N 50064946 4-(4-Chloro-phenyl)-1-[4-(4-fluoro-phenyl)-4-hydroxy-butyl]-piperidin-4-ol::CHEMBL1036::Hydroxyhaloperidol D(2) dopamine receptor Rattus norvegicus 241 ChEMBL 10.1021/acs.jmedchem.6b01039 10.7270/Q2RR22W8 27739690 Olivieri, M; Amata, E; Vinciguerra, S; Fiorito, J; Giurdanella, G; Drago, F; Caporarello, N; Prezzavento, O; Arena, E; Salerno, L; Rescifina, A; Lupo, G; Anfuso, CD; Marrazzo, A University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50064946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50064946&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 119265 103959901 CHEMBL1036 ZINC04257980 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51361382 OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 LNEPOXFFQSENCJ-UHFFFAOYSA-N 21398 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)::4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one::CHEMBL54::CHEMBL545608::Haloperidol::Haloperidol, 1 D(2) dopamine receptor Rattus norvegicus 2.5 ChEMBL 10.1021/acs.jmedchem.6b01039 10.7270/Q2RR22W8 27739690 Olivieri, M; Amata, E; Vinciguerra, S; Fiorito, J; Giurdanella, G; Drago, F; Caporarello, N; Prezzavento, O; Arena, E; Salerno, L; Rescifina, A; Lupo, G; Anfuso, CD; Marrazzo, A University of Catania http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21398&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search GMJ 6X10,6DJZ,6LUQ 3559 49689470 5613 CHEMBL54CHEMBL545608 DB00502 86 C01814 ZINC00537822 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51412675 FC(F)(F)c1cccc(c1)N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 InChI=1S/C22H24F3N3O3S/c23-22(24,25)17-6-5-7-18(16-17)27-14-12-26(13-15-27)10-3-4-11-28-21(29)19-8-1-2-9-20(19)32(28,30)31/h1-2,5-9,16H,3-4,10-15H2 BFNRVMJMTPNWFK-UHFFFAOYSA-N 50216051 2-(4-(4-(3-a,a,a-trifluorotolyl)-1-piperazinyl)butyl)-1, 2-benzisothiazole-3(2H)-one 1,1-dioxide::CHEMBL238916 D(2) dopamine receptor Rattus norvegicus 2250 ChEMBL 10.1016/j.bmcl.2021.128028 10.7270/Q2XK8KBD 33839253 Kułaga, D; Jaśkowska, J; Satała, G Cracow University of Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50216051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50216051&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11134444 104090515 CHEMBL238916 ZINC28866101 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 1257701 CNCc1cc(OCc2cc(F)ccc2F)n(CC(C)(C)C)n1 InChI=1S/C17H23F2N3O/c1-17(2,3)11-22-16(8-14(21-22)9-20-4)23-10-12-7-13(18)5-6-15(12)19/h5-8,20H,9-11H2,1-4H3 ZEOZGDUGZVKRTI-UHFFFAOYSA-N 322094 1-{5-[(2,5-difluorobenzyl)oxy]-1-(2,2-dimethylpropyl)-1H-pyrazol-3-yl}-N-methylmethanamine::US10183913, Example 258::US11312688, Example 258::US11576897, Example 258 D(2) dopamine receptor Rattus norvegicus >1000 US Patent 10.7270/Q2J67MVZ US11576897 Kato, T; Shimizu, S Sumitomo Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=322094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=322094&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56601749 384225173 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 1257697 CNCc1cc(OCc2cc(Cl)ccc2F)n(CCC(C)(C)CO)n1 InChI=1S/C18H25ClFN3O2/c1-18(2,12-24)6-7-23-17(9-15(22-23)10-21-3)25-11-13-8-14(19)4-5-16(13)20/h4-5,8-9,21,24H,6-7,10-12H2,1-3H3 JFNIBJVZOJNQSF-UHFFFAOYSA-N 593002 US11576897, Example 275 D(2) dopamine receptor Rattus norvegicus >1000 US Patent 10.7270/Q2J67MVZ US11576897 Kato, T; Shimizu, S Sumitomo Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=593002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=593002&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 158901654 479271178 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 1257698 CNCc1cc(OCc2cc(F)c(F)cc2F)n(CCC(C)C)n1 InChI=1S/C17H22F3N3O/c1-11(2)4-5-23-17(7-13(22-23)9-21-3)24-10-12-6-15(19)16(20)8-14(12)18/h6-8,11,21H,4-5,9-10H2,1-3H3 RUZMVEIDTULVHD-UHFFFAOYSA-N 322100 N-Methyl-1-{1-(3-methylbutyl)-5-[(2,4,5-trifluorobenzyl)-oxy]-1H-pyrazol-3-yl}methanamine hydrochloride::US10183913, Example 283::US11312688, Example 283::US11576897, Example 283 D(2) dopamine receptor Rattus norvegicus >1000 US Patent 10.7270/Q2J67MVZ US11576897 Kato, T; Shimizu, S Sumitomo Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=322100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=322100&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56601349 384225179 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 1257699 CC(C)(C)CCn1nc(CN)cc1OCc1cc(F)ccc1F InChI=1S/C17H23F2N3O/c1-17(2,3)6-7-22-16(9-14(10-20)21-22)23-11-12-8-13(18)4-5-15(12)19/h4-5,8-9H,6-7,10-11,20H2,1-3H3 ROHYQGMWNOOUHT-UHFFFAOYSA-N 593038 1-[5-{[(2,5-difluorophenyl)methyl]oxy}-1-(3,3-dimethylbutyl)-1H-pyrazol-3-yl]methanamine::US11576897, Example 485 D(2) dopamine receptor Rattus norvegicus >1000 US Patent 10.7270/Q2J67MVZ US11576897 Kato, T; Shimizu, S Sumitomo Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=593038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=593038&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 135230841 479271211 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 1257700 CNCc1cc(OCc2cc(F)ccc2F)n(CCC(C)(C)C)n1 InChI=1S/C18H25F2N3O/c1-18(2,3)7-8-23-17(10-15(22-23)11-21-4)24-12-13-9-14(19)5-6-16(13)20/h5-6,9-10,21H,7-8,11-12H2,1-4H3 CESJQKNECLKVHF-UHFFFAOYSA-N 322096 1-{5-[(2,5-difluorobenzyl)oxy]-1-(3,3-dimethylbutyl)-1H-pyrazol-3-yl}-N-methylmethanamine::US10183913, Example 266::US11312688, Example 266::US11576897, Example 500 D(2) dopamine receptor Rattus norvegicus >1000 US Patent 10.7270/Q2J67MVZ US11576897 Kato, T; Shimizu, S Sumitomo Pharma Co., Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=322096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=322096&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 56601150 384225175 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51463683 COc1ccccc1N1CCN(CCn2cc(COCC(COc3ccc(cc3)[Si]([18F])(C(C)(C)C)C(C)(C)C)OCc3cn(CCN4CCN(CC4)c4ccccc4OC)nn3)nn2)CC1 InChI=1S/C49H71FN10O5Si/c1-48(2,3)66(50,49(4,5)6)43-19-17-41(18-20-43)65-38-42(64-36-40-34-60(54-52-40)32-26-56-23-29-58(30-24-56)45-14-10-12-16-47(45)62-8)37-63-35-39-33-59(53-51-39)31-25-55-21-27-57(28-22-55)44-13-9-11-15-46(44)61-7/h9-20,33-34,42H,21-32,35-38H2,1-8H3/i50-1 GEERKEFZZKDAPM-RIIFNPPHSA-N 50590648 CHEMBL5202019 D(2) dopamine receptor Rattus norvegicus 2.2 ChEMBL 10.7270/Q26M3BS8 35939391 Fu, H; Rong, J; Chen, Z; Zhou, J; Collier, T; Liang, SH Beijing Normal University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50590648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50590648&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 86287590 482601500 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51463695 CN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O InChI=1S/C24H28FN3O2/c1-26-18-28(21-6-3-2-4-7-21)24(23(26)30)13-16-27(17-14-24)15-5-8-22(29)19-9-11-20(25)12-10-19/h2-4,6-7,9-12H,5,8,13-18H2,1H3 QHJLPOSPWKZACG-UHFFFAOYSA-N 50004813 8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one (N-methylspiperone,NMSP)::CHEMBL267932 D(2) dopamine receptor Rattus norvegicus 0.230000 ChEMBL 10.7270/Q26M3BS8 35939391 Fu, H; Rong, J; Chen, Z; Zhou, J; Collier, T; Liang, SH Beijing Normal University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004813&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 119146 103918360 CHEMBL267932 196 ZINC02572278 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51463701 CCN(CC)C(=O)[C@H]1CN(C)C2Cc3c(Br)n(C)c4cccc(C2=C1)c34 InChI=1S/C21H26BrN3O/c1-5-25(6-2)21(26)13-10-15-14-8-7-9-17-19(14)16(20(22)24(17)4)11-18(15)23(3)12-13/h7-10,13,18H,5-6,11-12H2,1-4H3/t13-,18?/m1/s1 KLMFUBCMJSPRPY-YJJYDOSJSA-N 50590651 CHEMBL5172469 D(2) dopamine receptor Rattus norvegicus 3.9 ChEMBL 10.7270/Q26M3BS8 35939391 Fu, H; Rong, J; Chen, Z; Zhou, J; Collier, T; Liang, SH Beijing Normal University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50590651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50590651&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 168270256 482601503 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51463720 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) FPCCSQOGAWCVBH-UHFFFAOYSA-N 21395 3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H,3H)-quinazolinedione::3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione::CHEMBL1628637::CHEMBL51::Ketanserin::R-41,468::R-41-468::R41,468::[3H]-Ketanserin D(2) dopamine receptor Rattus norvegicus 220 ChEMBL 10.7270/Q26M3BS8 35939391 Fu, H; Rong, J; Chen, Z; Zhou, J; Collier, T; Liang, SH Beijing Normal University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21395&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3822 49689467 6123 CHEMBL51CHEMBL1628637 197 C07464 ZINC00537877 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51463725 Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=S)[nH]c3ccccc3c2=O)CC1 InChI=1S/C22H22FN3O2S/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29) SMYALUSCZJXWHG-UHFFFAOYSA-N 50113332 3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one::3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-2-thioxo-2,3-dihydro-1H-quinazolin-4-one::CHEMBL62919::altanserin D(2) dopamine receptor Rattus norvegicus 62 ChEMBL 10.7270/Q26M3BS8 35939391 Fu, H; Rong, J; Chen, Z; Zhou, J; Collier, T; Liang, SH Beijing Normal University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113332 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113332&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3033677 104007681 CHEMBL62919 C11734 ZINC26174383 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51463727 Cc1nc2SCCn2c(=O)c1CCN1CCC(CC1)C(=O)c1ccc(F)cc1 InChI=1S/C21H24FN3O2S/c1-14-18(20(27)25-12-13-28-21(25)23-14)8-11-24-9-6-16(7-10-24)19(26)15-2-4-17(22)5-3-15/h2-5,16H,6-13H2,1H3 RBGAHDDQSRBDOG-UHFFFAOYSA-N 81814 5H-THIAZOLO[3,2A]PYRIMIDIN-5-ONE, 6-[2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL]-2,3-DIHYDRO-7-METHYL-::CAS_86487-64-1::SEPTOPERONE::SETOPERONE D(2) dopamine receptor Rattus norvegicus 24 ChEMBL 10.7270/Q26M3BS8 35939391 Fu, H; Rong, J; Chen, Z; Zhou, J; Collier, T; Liang, SH Beijing Normal University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=81814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=81814&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 68604 131342388 ZINC00538339 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51463732 CN1CCC(CC1)n1c(C)c(-c2ccc(F)cc2)c2cc(C)ccc12 InChI=1S/C22H25FN2/c1-15-4-9-21-20(14-15)22(17-5-7-18(23)8-6-17)16(2)25(21)19-10-12-24(3)13-11-19/h4-9,14,19H,10-13H2,1-3H3 JHXVZNYMJMMPEI-UHFFFAOYSA-N 50001809 3-(4-Fluoro-phenyl)-2,5-dimethyl-1-(1-methyl-piperidin-4-yl)-1H-indole::CHEMBL144362 D(2) dopamine receptor Rattus norvegicus 2600 ChEMBL 10.7270/Q26M3BS8 35939391 Fu, H; Rong, J; Chen, Z; Zhou, J; Collier, T; Liang, SH Beijing Normal University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50001809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50001809&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 10427137 103916182 CHEMBL144362 ZINC00015635 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51516334 CCCN(CCC)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-8-9-15-13(12-14)6-5-7-16(15)18/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1 MDBWEQVKJDMEMK-AWEZNQCLSA-N 50115277 (2R,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2R,3S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(2S,3R)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-(-)-5-hydroxy-2-(N,N-di-n-propylamino)tetralin::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::(S)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol.HCl::6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol::CHEMBL269004 D(2) dopamine receptor Rattus norvegicus 153 ChEMBL 10.7270/Q2NP28MJ 36571976 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50115277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50115277&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 11299620 104009254 CHEMBL269004 ZINC05833082 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51516335 CCCN(CCCCCCCCCCN(CCC)[C@@H]1CCc2c(O)cccc2C1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C36H56N2O2/c1-3-23-37(31-19-21-33-29(27-31)15-13-17-35(33)39)25-11-9-7-5-6-8-10-12-26-38(24-4-2)32-20-22-34-30(28-32)16-14-18-36(34)40/h13-18,31-32,39-40H,3-12,19-28H2,1-2H3/t31-,32+ SQYZBSPQNGOKJY-MEKGRNQZSA-N 50610247 CHEMBL5276671 D(2) dopamine receptor Rattus norvegicus 2.0 ChEMBL 10.7270/Q2NP28MJ 36571976 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610247&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 171352256 494499995 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51516336 CCCN(CCN1CCN(CCN(CCC)[C@H]2CCc3c(O)cccc3C2)CC1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C34H52N4O2/c1-3-15-37(29-11-13-31-27(25-29)7-5-9-33(31)39)23-21-35-17-19-36(20-18-35)22-24-38(16-4-2)30-12-14-32-28(26-30)8-6-10-34(32)40/h5-10,29-30,39-40H,3-4,11-26H2,1-2H3/t29-,30-/m0/s1 LRRBYETUNOFXFL-KYJUHHDHSA-N 50610248 CHEMBL5274131 D(2) dopamine receptor Rattus norvegicus 12 ChEMBL 10.7270/Q2NP28MJ 36571976 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610248&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 171357190 494499996 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51516337 CCCN(CCc1ccc(CCN(CCC)[C@H]2CCc3c(O)cccc3C2)cc1)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C36H48N2O2/c1-3-21-37(31-15-17-33-29(25-31)7-5-9-35(33)39)23-19-27-11-13-28(14-12-27)20-24-38(22-4-2)32-16-18-34-30(26-32)8-6-10-36(34)40/h5-14,31-32,39-40H,3-4,15-26H2,1-2H3/t31-,32-/m0/s1 FEACLLHVUMUKOS-ACHIHNKUSA-N 50610249 CHEMBL5282690 D(2) dopamine receptor Rattus norvegicus 3.9 ChEMBL 10.7270/Q2NP28MJ 36571976 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610249&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 171353860 494499997 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51516338 CCCN(CCc1ccc(CCN(CCC)[C@H]2CCc3c(O)cccc3C2)cc1)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C33H46N4OS/c1-3-18-36(27-12-14-29-26(22-27)6-5-7-31(29)38)20-16-24-8-10-25(11-9-24)17-21-37(19-4-2)28-13-15-30-32(23-28)39-33(34)35-30/h5-11,27-28,38H,3-4,12-23H2,1-2H3,(H2,34,35)/t27-,28-/m0/s1 SGWUMXOWOUGLMJ-NSOVKSMOSA-N 50610250 CHEMBL5267221 D(2) dopamine receptor Rattus norvegicus 4.9 ChEMBL 10.7270/Q2NP28MJ 36571976 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610250&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 171350456 494499998 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51516339 Br.Br.CCCN(CCc1cc(O)c(CCN(CCC)[C@H]2CCc3c(O)cccc3C2)cc1O)[C@H]1CCc2c(O)cccc2C1 InChI=1S/C36H48N2O4.2BrH/c1-3-17-37(29-11-13-31-25(21-29)7-5-9-33(31)39)19-15-27-23-36(42)28(24-35(27)41)16-20-38(18-4-2)30-12-14-32-26(22-30)8-6-10-34(32)40;;/h5-10,23-24,29-30,39-42H,3-4,11-22H2,1-2H3;2*1H/t29-,30-;;/m0../s1 JHMPBPUPTSSMTN-ARDORAJISA-N 50610251 CHEMBL5272529 D(2) dopamine receptor Rattus norvegicus 7.6 ChEMBL 10.7270/Q2NP28MJ 36571976 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610251&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 171345203 494499999 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51516340 CCCN(CCc1cc(O)c(CCN(CCC)[C@H]2CCc3nc(N)sc3C2)cc1O)[C@H]1CCc2nc(N)sc2C1 InChI=1S/C30H44N6O2S2/c1-3-11-35(21-5-7-23-27(17-21)39-29(31)33-23)13-9-19-15-26(38)20(16-25(19)37)10-14-36(12-4-2)22-6-8-24-28(18-22)40-30(32)34-24/h15-16,21-22,37-38H,3-14,17-18H2,1-2H3,(H2,31,33)(H2,32,34)/t21-,22-/m0/s1 WLQPRUMGPAOCRW-VXKWHMMOSA-N 50610252 CHEMBL5266134 D(2) dopamine receptor Rattus norvegicus 55 ChEMBL 10.7270/Q2NP28MJ 36571976 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610252&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 146442443 494500000 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51516341 CCCN(CCc1ccc(CCN(CCC)[C@H]2CCc3c(O)cccc3C2)cc1)[C@@H]1CCc2cc(O)c(O)cc2C1 InChI=1S/C36H48N2O3/c1-3-18-37(31-13-12-28-24-35(40)36(41)25-30(28)23-31)20-16-26-8-10-27(11-9-26)17-21-38(19-4-2)32-14-15-33-29(22-32)6-5-7-34(33)39/h5-11,24-25,31-32,39-41H,3-4,12-23H2,1-2H3/t31-,32+/m1/s1 FWACCHRUKMDWQL-ZWXJPIIXSA-N 50610253 CHEMBL5283620 D(2) dopamine receptor Rattus norvegicus 8.3 ChEMBL 10.7270/Q2NP28MJ 36571976 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50610253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50610253&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 171348578 494500001 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51575314 C\C(CO)=C\CC[C@]1(C)[C@H]2CC3[C@H](C2)[C@]13C InChI=1S/C15H24O/c1-10(9-16)5-4-6-14(2)11-7-12-13(8-11)15(12,14)3/h5,11-13,16H,4,6-9H2,1-3H3/b10-5-/t11-,12+,13?,14-,15-/m1/s1 PDEQKAVEYSOLJX-XGUMIZKCSA-N 50633730 CHEMBL5435489 D(2) dopamine receptor Rattus norvegicus 75000 ChEMBL 10.1021/acs.jnatprod.3c00282 10.7270/Q2PG1X6W 37450763 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50633730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50633730&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51540163 COc1ccccc1N1CCN(CCCCN2C(=O)C3C(C2=O)C2(C)C(=O)C3(C)C(=C2c2ccccc2)c2ccccc2)CC1 InChI=1S/C38H41N3O4/c1-37-30(26-14-6-4-7-15-26)31(27-16-8-5-9-17-27)38(2,36(37)44)33-32(37)34(42)41(35(33)43)21-13-12-20-39-22-24-40(25-23-39)28-18-10-11-19-29(28)45-3/h4-11,14-19,32-33H,12-13,20-25H2,1-3H3 UIUZCPPYQICTIK-UHFFFAOYSA-N 50619380 CHEMBL5422403 D(2) dopamine receptor Rattus norvegicus 11600 ChEMBL 10.1016/j.bmc.2023.117518 10.7270/Q27H1PZ5 37951135 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50619380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50619380&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51540164 CC12C3C(C(=O)N(CCCCN4CCN(CC4)c4ncccn4)C3=O)C(C)(C1=O)C(=C2c1ccccc1)c1ccccc1 InChI=1S/C35H37N5O3/c1-34-26(24-12-5-3-6-13-24)27(25-14-7-4-8-15-25)35(2,32(34)43)29-28(34)30(41)40(31(29)42)19-10-9-18-38-20-22-39(23-21-38)33-36-16-11-17-37-33/h3-8,11-17,28-29H,9-10,18-23H2,1-2H3 WKPOTXYGXPWOOG-UHFFFAOYSA-N 50619381 CHEMBL5403228 D(2) dopamine receptor Rattus norvegicus 22600 ChEMBL 10.1016/j.bmc.2023.117518 10.7270/Q27H1PZ5 37951135 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50619381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50619381&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51540165 CC12C3C(C(=O)N(CCCCN4CCN(CC4)c4ccccn4)C3=O)C(C)(C1=O)C(=C2c1ccccc1)c1ccccc1 InChI=1S/C36H38N4O3/c1-35-28(25-13-5-3-6-14-25)29(26-15-7-4-8-16-26)36(2,34(35)43)31-30(35)32(41)40(33(31)42)20-12-11-19-38-21-23-39(24-22-38)27-17-9-10-18-37-27/h3-10,13-18,30-31H,11-12,19-24H2,1-2H3 DLUWIXMSKRANKF-UHFFFAOYSA-N 50619382 CHEMBL5437394 D(2) dopamine receptor Rattus norvegicus 50300 ChEMBL 10.1016/j.bmc.2023.117518 10.7270/Q27H1PZ5 37951135 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50619382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50619382&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51540166 CC12C3C(C(=O)N(CCCCN4CCN(CC4)c4ccccc4Cl)C3=O)C(C)(C1=O)C(=C2c1ccccc1)c1ccccc1 InChI=1S/C37H38ClN3O3/c1-36-29(25-13-5-3-6-14-25)30(26-15-7-4-8-16-26)37(2,35(36)44)32-31(36)33(42)41(34(32)43)20-12-11-19-39-21-23-40(24-22-39)28-18-10-9-17-27(28)38/h3-10,13-18,31-32H,11-12,19-24H2,1-2H3 AHOOAVKYZNZARG-UHFFFAOYSA-N 50619383 CHEMBL5435378 D(2) dopamine receptor Rattus norvegicus 8400 ChEMBL 10.1016/j.bmc.2023.117518 10.7270/Q27H1PZ5 37951135 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50619383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50619383&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51540167 CC12C3C(C(=O)N(CCCCN4CCN(CC4)c4cccc(Cl)c4)C3=O)C(C)(C1=O)C(=C2c1ccccc1)c1ccccc1 InChI=1S/C37H38ClN3O3/c1-36-29(25-12-5-3-6-13-25)30(26-14-7-4-8-15-26)37(2,35(36)44)32-31(36)33(42)41(34(32)43)19-10-9-18-39-20-22-40(23-21-39)28-17-11-16-27(38)24-28/h3-8,11-17,24,31-32H,9-10,18-23H2,1-2H3 YDTHKQISEOGROC-UHFFFAOYSA-N 50619384 CHEMBL5409943 D(2) dopamine receptor Rattus norvegicus 24800 ChEMBL 10.1016/j.bmc.2023.117518 10.7270/Q27H1PZ5 37951135 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50619384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50619384&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51540168 CC12C3C(C(=O)N(CCCCN4CCN(CC4)c4ccccc4F)C3=O)C(C)(C1=O)C(=C2c1ccccc1)c1ccccc1 InChI=1S/C37H38FN3O3/c1-36-29(25-13-5-3-6-14-25)30(26-15-7-4-8-16-26)37(2,35(36)44)32-31(36)33(42)41(34(32)43)20-12-11-19-39-21-23-40(24-22-39)28-18-10-9-17-27(28)38/h3-10,13-18,31-32H,11-12,19-24H2,1-2H3 OJOGIPKODKYGNO-UHFFFAOYSA-N 50619385 CHEMBL5395179 D(2) dopamine receptor Rattus norvegicus 18300 ChEMBL 10.1016/j.bmc.2023.117518 10.7270/Q27H1PZ5 37951135 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50619385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50619385&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953 51540169 Clc1ccc2n(C3CCN(CCCn4c5ccccc5[nH]c4=O)CC3)c(=O)[nH]c2c1 InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) FGXWKSZFVQUSTL-UHFFFAOYSA-N 50241107 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one::5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol::5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)::5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one::5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)::CHEMBL219916::DOMPERIDONE::DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::US11147820, Compound Domperidone::US9132134, Domperidone D(2) dopamine receptor Rattus norvegicus 1.000000 ChEMBL 10.1016/j.bmc.2023.117518 10.7270/Q27H1PZ5 37951135 n/a n/a http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3630&target=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241107&enzyme=D%282%29+dopamine+receptor&column=ki&startPg=0&Increment=50&submit=Search 3151 104098608 31515 CHEMBL219916 DB01184 965 ZINC19632603 1 MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC 6VMS D(2) dopamine receptor DRD2_RAT P61169 P13953